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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2025 Volume 31 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Heat shock protein 22: A new direction for cardiovascular disease (Review) Corrigendum in /10.3892/mmr.2025.13535

Yi Chen, Meng Li, Yanqing Wu
Article Number: 82
Published online on: 27 January 2025

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RMRP variants inhibit the cell cycle checkpoints pathway in cartilage‑hair hypoplasia

Jian Gao, Junge Zheng, Shiguo Chen, Sheng Lin, Shan Duan
Article Number: 81
Published online on: 27 January 2025

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Pin1 as a central node in oncogenic signaling: Mechanistic insights and clinical prospects (Review)

Shuning Lei, Min Luo, Yuxue Wang
Article Number: 80
Published online on: 27 January 2025

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Establishment and verification of a prognostic signature associated with fatty acid metabolism in endometrial cancer

Lu Peng, Rui Sun, Tingting Hao, Yulong Mu, Qing Zhang, Jie Jiang, Helgi B. Schiöth, Ruifen Dong
Article Number: 79
Published online on: 27 January 2025

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Mitochondrial DNA copy number alterations: Key players in the complexity of glioblastoma (Review)

Abdul Aziz Mohamed Yusoff, Siti Zulaikha Nashwa Mohd Khair, Siti Muslihah Abd Radzak
Article Number: 78
Published online on: 24 January 2025

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Preconditioning with acteoside ameliorates myocardial ischemia‑reperfusion injury by targeting HSP90AA1 and the PI3K/Akt signaling pathway

Jing Li, Yuxin Guo, Yang Yang, Qing Xue, Hong Cao, Guangyuan Yang, Linlin Jia, Haibo Yu
Article Number: 77
Published online on: 24 January 2025

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Ameliorative effects of Asiasarum root and rhizome extract on high fat diet‑induced obesity in mice through regulation of the SIRT1/PGC1α/AMPK pathways in muscle and liver tissues

Chenzi Lyu, Seok Yong Kang, Haifeng Shao, Dongeun Kim, Hyo Won Jung
Article Number: 76
Published online on: 24 January 2025

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Multifaceted roles of insulin‑like growth factor 2 mRNA binding protein 2 in human cancer (Review)

Jianan Shen, Youxiang Ding
Article Number: 75
Published online on: 24 January 2025

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Article Open Access

Triptolide reverses cis‑diamminedichloroplatinum resistance in esophageal squamous cell carcinoma by suppressing glycolysis and causing mitochondrial malfunction

Kuiyuan Liu, Jia Liu, Tiebao Meng, Nan Wu, Juntao Liu, Mingxu Qiao, Liangyi Dong, Jingeng Liu
Article Number: 74
Published online on: 24 January 2025

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Article Open Access

Exosomal SphK1 from colorectal cancer cells promotes cancer cell migration and activates hepatic stellate cells

Wenlu Zhang, Chunyan Xu
Article Number: 73
Published online on: 23 January 2025

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Review Open Access

Insulin receptor tyrosine kinase substrate in health and disease (Review)

Xueyan Zhang, Zhewen Zhang
Article Number: 72
Published online on: 23 January 2025

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Article Open Access

Calycosin‑7‑O‑β‑D‑glucoside downregulates mitophagy by mitigating mitochondrial fission to protect HT22 cells from oxygen‑glucose deprivation/reperfusion‑induced injury

Xiangli Yan, Siqi Quan, Roujia Guo, Zibo Li, Ming Bai, Baoying Wang, Pan Su, Erping Xu, Yucheng Li
Article Number: 71
Published online on: 13 January 2025

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Retraction Open Access

[Retracted] Tan IIA inhibits H1299 cell viability through the MDM4‑IAP3 signaling pathway

Yukun Zu, Jianning Wang, Wei Ping, Wei Sun
Article Number: 70
Published online on: 13 January 2025

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Expression of the IGF‑1Ea isoform in human placentas from third trimester normal and idiopathic intrauterine growth restriction singleton pregnancies: Correlations with clinical and histopathological parameters

Apostolos Fasoulopoulos, Michail Varras, Fani-Niki Varra, Anastasios Philippou, Despina Myoteri, Viktoria-Konstantina Varra, Evgenia Kouroglou, Alexandros Gryparis, Argyro Papadopetraki, Iakovos Vlachos, Konstantinos Papadopoulos, Michael Koutsilieris, Anastasia Evangelia Konstantinidou
Article Number: 69
Published online on: 09 January 2025

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New insights into the role of complement system in colorectal cancer (Review)

Yuwen Xu, Jiaqi Zhou, Yuanyuan Wu, Jie Shen, Xiaoyan Fu, Meifang Liu, Shujuan Liang
Article Number: 68
Published online on: 09 January 2025

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NGR1 reduces neuronal apoptosis through regulation of ITGA11 following subarachnoid hemorrhage

Yu Hou, Lihan Zhang, Wenzhe Ma, Yong Jiang
Article Number: 67
Published online on: 08 January 2025

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Integrated transcriptomics and proteomics analysis of the impact of iodine‑125 in hepatocellular carcinoma

Yang Yang, Wei Yang, Jie Shen, Enci Ding
Article Number: 66
Published online on: 06 January 2025

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Article Open Access

Application of integrated omics in aseptic loosening of prostheses after hip replacement

Yun-Ke Liu, Yong-Hui Dong, Xia-Ming Liang, Shuo Qiang, Meng-En Li, Zhuang Sun, Xin Zhao, Zhi-Hua Yan, Jia Zheng
Article Number: 65
Published online on: 03 January 2025

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Adiponectin targets the AMPK/mTOR signaling pathway to alleviate cognitive impairment in epilepsy

Yaoyuan Zhang, Zhenzhen Qu, Zhuofeng Mao, Hu Liu, Weiping Wang, Lijing Jia
Article Number: 64
Published online on: 03 January 2025

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Retraction Open Access

[Retracted] Tanshinone IIA improves hypoxic ischemic encephalopathy through TLR‑4‑mediated NF‑κB signal pathway

Chengzhi Fang, Lili Xie, Chunmei Liu, Chunhua Fu, Wei Ye, Hong Liu, Binghong Zhang
Article Number: 63
Published online on: 03 January 2025

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Review Open Access

Annexin A1: The dawn of ischemic stroke (Review)

Chen Tang, Rui Lan, Dong-Rui Ma, Min Zhao, Yong Zhang, Hong-Yu Li, Shuang Liu, Bo-Yang Li, Jie-Li Yang, Hui-Jie Yang, Zhen-Qiang Zhang
Article Number: 62
Published online on: 31 December 2024

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Viruses and psychiatric disorders: We have not crossed the borderline from hypothesis to proof yet (Review)

Nikolaos Siafakas, Cleo Anastassopoulou, Spyridon Pournaras, Athanasios Tsakris, Evangelos Alevizakis, Stylianos Kympouropoulos, Demetrios A. Spandidos, Emmanouil Rizos
Article Number: 61
Published online on: 31 December 2024

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Quercetin attenuates the symptoms of osteoarthritis in vitro and in vivo by suppressing ferroptosis via activation of AMPK/Nrf2/Gpx4 signaling

Shiyu Dong, Xiaoliang Li, Genrong Xu, Liming Chen, Jiyang Zhao
Article Number: 60
Published online on: 24 December 2024

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Insights into renal damage in hyperuricemia: Focus on renal protection (Review)

Hang Yang, Jie Ying, Tong Zu, Xiao-Ming Meng, Juan Jin
Article Number: 59
Published online on: 24 December 2024

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Retraction Open Access

[Retracted] NG25, an inhibitor of transforming growth factor‑β‑activated kinase 1, ameliorates neuronal apoptosis in neonatal hypoxic‑ischemic rats

Hua Wang, Zhong Chen, Yu Li, Qiaoyun Ji
Article Number: 58
Published online on: 23 December 2024

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Prospects for potential therapy targeting immune‑associated factors in endometriosis (Review)

Wenwen Zhang, Kang Li, Aiwen Jian, Guanran Zhang, Xiaoli Zhang
Article Number: 57
Published online on: 23 December 2024

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Article Open Access

Epigenetic downregulation of the proapoptotic gene HOXA5 in oral squamous cell carcinoma

Ying-Ju Chen, Shin-Wei Liao, Yen-Ling Lai, Yu-Fen Li, Yin-Che Lu, Chien-Kuo Tai
Article Number: 56
Published online on: 19 December 2024

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NEDD4 enhances bone‑tendon healing in rotator cuff tears by reducing fatty infiltration

Jian Li, Ying Peng, Dong Zhen, Caifen Guo, Wuxun Peng
Article Number: 55
Published online on: 17 December 2024

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Retraction Open Access

[Retracted] Limb remote ischemic post‑conditioning reduces injury and improves long‑term behavioral recovery in rats following subarachnoid hemorrhage: Possible involvement of the autophagic process

Xiang Hu, Tao Lv, Shao-Feng Yang, Xiao-Hua Zhang, Yi-Feng Miao
Article Number: 54
Published online on: 17 December 2024

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Journal Cover
September-2026 Volume 34 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Chronic kidney disease‑associated encephalopathy: Clinical features, pathomechanisms and emerging therapeutic strategies (Review)

Nanling Zeng, Ling Jiang, Yang Zhang, Jian Liu, Qiong Zhang, Lishang Liao, Qiongdan Hu
Article Number: 259
Published online on: 21 July 2026

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Retraction Open Access

[Retracted] Emodin promotes the arrest of human lymphoma Raji cell proliferation through the UHRF1‑DNMT3A‑∆Np73 pathways

Yun Lin, Weiming Chen, Zhihong Wang, Pengwei Cai
Article Number: 258
Published online on: 20 July 2026

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Article Open Access

Sedanolide alleviates LPS‑induced depressive‑like behaviors by modulating the C3a/C3aR signaling axis and microglial glycolysis

Shaocong Lu, Fangla Luo, Niqi Chen, Gongde Shi, Yeru Chen
Article Number: 257
Published online on: 16 July 2026

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Expression of Concern Open Access

[Expression of Concern] Chrysophanol inhibits proliferation and induces apoptosis through NF‑κB/cyclin D1 and NF‑κB/Bcl‑2 signaling cascade in breast cancer cell lines

Li Ren, Zhouping Li, Chunmei Dai, Danyu Zhao, Yanjie Wang, Chunyu Ma, Chun Liu
Article Number: 256
Published online on: 15 July 2026

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Article Open Access

PCSK9 alleviates doxorubicin‑induced pyroptosis of cardiomyocytes

Chaochu Cui, Jinyu Zhao, Xiaoqian Li, Shengming Huang, Gang Liu, Xinhui Xu, Can Guo, Tiesuo Zhao, Jiang Du, Shipeng Li, Xianwei Wang, Jianbo Yang
Article Number: 255
Published online on: 14 July 2026

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Review Open Access

From cell to disease: Regulatory networks and mechanisms of super‑enhancers in aging (Review)

Xiaodan Wang, Weiqian Deng, Shuangxi Tu, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 254
Published online on: 14 July 2026

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Retraction Open Access

[Retracted] Matrine‑induced apoptosis in Hep3B cells via the inhibition of MDM2

Ning Zhou, Jiequn Li, Ting Li, Guangshun Chen, Zhongqiang Zhang, Zhongzhou Si
Article Number: 253
Published online on: 13 July 2026

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Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review)

Lan Wang, Zhiyuan Ma, Bei Ji, Shuhui Liu, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 252
Published online on: 09 July 2026

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Article

Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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Correction Open Access

[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
Published online on: 07 July 2026

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Review Open Access

Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Article Open Access

Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Review Open Access

Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Review Open Access

Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Article Open Access

Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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Review Open Access

TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Article Open Access

Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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Retraction Open Access

[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Article Open Access

Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Article Open Access

Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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Journal Cover
October-2026 Volume 34 Issue 4

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Advances in miR‑200c regulation of apoptosis, pyroptosis and autophagy in disease (Review)

Xiaona Wang, Hua Du, Yingxu Shi
Article Number: 264
Published online on: 28 July 2026

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Review Open Access

Association between periodontitis and heart failure: Mechanisms and clinical implications (Review)

Xinyue Zhang, Xiaoli An
Article Number: 263
Published online on: 28 July 2026

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Article Open Access

Ginsenosides alleviate the progression of hepatic fibrosis by targeting the liver circadian clock gene CLOCK

Jiawen Yu, Chunmei Qian, Renye Que, Yi Zhou
Article Number: 262
Published online on: 28 July 2026

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Retraction Open Access

[Retracted] PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin, Yuezhong Shen, Jingyang Su
Article Number: 261
Published online on: 27 July 2026

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Article Open Access

UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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