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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-August 2003 Volume 10 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Evaluating prostate cancer cell culturing methods: A comparison of cell morphologies and metabolic activity

Jennifer J. Winkenwerder, Patricia L. Palechek, Julie S. Reece, Mark A. Saarinen, Mark A. Arnold, Michael B. Cohen, David W. Murhammer
Pages: 783-789
Published online on: 01 July 2003

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Article

Immunohistochemical analysis of estrone sulfatase and aromatase in human breast cancer tissues

Yutaka Yamamoto, Jun-Ichi Yamashita, Masakazu Toi, Mariko Muta, Shigenori Nagai, Nobuo Hanai, Akiko Furuya, Yoshio Osawa, Shigehira Saji, Michio Ogawa
Pages: 791-796
Published online on: 01 July 2003

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Article

Hypoxia-inducible factor-1α expression and angiogenesis in gastrointestinal stromal tumor of the stomach

Ryoji Takahashi, Shinji Tanaka, Toru Hiyama, Masanori Ito, Yasuhiko Kitadai, Masaharu Sumii, Ken Haruma, Kazuaki Chayama
Pages: 797-802
Published online on: 01 July 2003

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Article

Prognostic factors in the so-called malignant mesenchymoma: A clinicopathological and immunohistochemical analysis

Toshisada Adachi, Yoshinao Oda, Akio Sakamoto, Takahiro Terashi, Sadafumi Tamiya, Yoichi Hachitanda, Masazumi Tsuneyoshi
Pages: 803-811
Published online on: 01 July 2003

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Article

The elevated serum interleukin-6 correlates with the increased serum butyrate level in patients with nasopharyngeal carcinoma

Kuan-Chih Chow, Shiow-Her Chiou, Shu-Peng Ho, Ming-Hsui Tsai, Chi-Long Chen, Liang-Shun Wang, Kwan-Hwa Chi
Pages: 813-819
Published online on: 01 July 2003

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Article

Clinical experience of ureteroscopic treatment for ureteral transitional cell carcinoma using the Holmium: YAG laser

Yoshiaki Yamada, Nobuaki Honda, Kogenta Nakamura, Hatsuki Hibi, Hiroshi Nanaura, Eiji Nishikawa, Ayumi Kamijou, Kenji Mitsui, Tomohiro Taki, Shigeyuki Aoki, Hiroto Kokubo, Hidetoshi Fukatsu
Pages: 821-825
Published online on: 01 July 2003

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Article

Prognostic significance of p27/kip1 and apoptosis in patients with colorectal carcinoma

Tsuyoshi Noguchi, Ryuichi Kikuchi, Kiyoshi Ono, Shinsuke Takeno, Hatsuo Moriyama, Yuzo Uchida
Pages: 827-831
Published online on: 01 July 2003

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Article

Prognostic significance of scoring system based on histological heterogeneity of invasive ductal carcinoma for node-negative breast cancer patients

Masafumi Kurosumi, Toshio Tabei, Kenichi Inoue, Hiroyuki Takei, Jun Ninomiya, Rin Naganuma, Kimito Suemasu, Yasuhiro Higashi, Eiju Tsuchiya
Pages: 833-837
Published online on: 01 July 2003

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Article

Pentoxifylline inhibits leukocyte infiltration and splenocyte cytotoxicity against murine colon adenocarcinoma

Maciej Lazarczyk, Tomasz Grzela, Justyna Niderla, Jakub Golab, Grazyna Korczak-Kowalska, Monika Oldak, Piotr Skopinski
Pages: 839-843
Published online on: 01 July 2003

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Article

Kinetics of iodide uptake and efflux in various human thyroid cancer cells by expressing sodium iodide symporter gene via a recombinant adenovirus

Won Woo Lee, Boyoung Lee, Sung Jin Kim, Jungsun Jin, Dae Hyuk Moon, Heuiran Lee
Pages: 845-849
Published online on: 01 July 2003

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Article

Delayed methotrexate clearance in osteosarcoma patients treated with multiagent regimens of neoadjuvant chemotherapy

Gaetano Bacci, Stefano Ferrari, Alessandra Longhi, Cristiana Forni, Loretta Loro, Claudio Beghelli, Morena Tremosini, Michela Versari
Pages: 851-857
Published online on: 01 July 2003

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Article

Oncogenic pathway of sporadic colorectal cancer with novel germline missense mutations in the hMSH2 gene

Kanae Yamada, Xiaoling Zhong, Shinsaku Kanazawa, Junichi Koike, Kazunori Tsujita, Hiromichi Hemmi
Pages: 859-866
Published online on: 01 July 2003

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Article

The stability of dihydropyrimidine dehydrogenase activity in colorectal cancer tissue after resection

Sotaro Sadahiro, Toshiyuki Suzuki, Kenji Ishikawa, Tomoki Nakamura, Akemi Kamijo, Takeshi Saguchi, Seiei Yasuda, Tomoo Tajima, Hiroyasu Makuuchi, Chieko Murayama
Pages: 867-869
Published online on: 01 July 2003

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Article

Novel mutations of the cartilage oligomeric matrix protein (COMP) gene in two Japanese patients with pseudoachondroplasia

Hiroaki Nakayama, Yuichi Endo, Shigeo Aota, Masato Sato, Teizo Fujita, Shin-Ichi Kikuchi
Pages: 871-873
Published online on: 01 July 2003

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Article

Preventive effect of fermented brown rice and rice bran on diethylnitrosoamine and phenobarbital-induced hepatocarcinogenesis in male F344 rats

Masaki Katayama, Shigeyuki Sugie, Naoki Yoshimi, Yasuhiro Yamada, Keiko Sakata, Zheng Qiao, Teruaki Iwasaki, Hiroshi Kobayashi, Hideki Mori
Pages: 875-880
Published online on: 01 July 2003

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Article

Overexpression of the thrombospondin 2 (TSP2) gene modulated by the matrix metalloproteinase family expression and production in human colon carcinoma cell line

Junichiro Kamochi, Tetsuji Tokunaga, Yasushi Tomii, Yoshiyuki Abe, Hiroyuki Hatanaka, Hiroshi Kijima, Hitoshi Yamazaki, Norihito Watanabe, Shohei Matsuzaki, Yoshito Ueyama, Masato Nakamura
Pages: 881-884
Published online on: 01 July 2003

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Article

Phase II study of vinorelbine with low dose prednisone in the treatment of hormone-refractory metastatic prostate cancer

C. Robles, A. J. Furst, P. Sriratana, S. Lai, L. Chua, E. Donnelly, J. Solomon, M. Sundaram, L. Feun, N. Savaraj
Pages: 885-889
Published online on: 01 July 2003

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Article

Recovery of stromal stem cells in bone sarcoma patients after chemotherapy: Implication for cell-based therapy in bone defect reconstruction

Amira Beccheroni, Enrico Lucarelli, Davide Donati, Luca Sangiorgi, Silvia Capponcelli, Marco Gorini, Annarosa Zambon Bertoja, Roberto Giardino, Mario Mercuri, Stefano Ferrari, Gaetano Bacci, Piero Picci
Pages: 891-896
Published online on: 01 July 2003

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Article

Inactivation of the RASSF1A in osteosarcoma

Sungjig Lim, Moon Ho Yang, Jae Hoon Park, Takayuki Nojima, Hiroshi Hashimoto, K. Krishnan Unni, Yong-Koo Park
Pages: 897-901
Published online on: 01 July 2003

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Article

The site of injection of tumor cells in rats does not influence the subsequent distribution of metastases

Dolores C. García-Olmo, María García-Rivas, Damián García-Olmo, Jesús Ontañón
Pages: 903-907
Published online on: 01 July 2003

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Article

Expression of the Mig (CXCL9) gene in murine lung carcinoma cells generated angiogenesis-independent antitumor effects

Yan-Qing Wang, Akihiko Wada, Shin-Ichi Ugai, Masatoshi Tagawa
Pages: 909-913
Published online on: 01 July 2003

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Article

Phase I study of liposomal daunorubicin in relapsed and refractory acute myeloid leukemia

Ralf Bieker, Christian Lerchenmüller, Jürgen Wehmeyer, Hubert L. Serve, Rolf M. Mesters, Thomas Büchner, Wolfgang E. Berdel
Pages: 915-920
Published online on: 01 July 2003

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Article

Endobronchial brachytherapy in combination with external beam irradiation in obstructing malignant bronchial tumors

Alain Prévost, Gérard Berthiot, Bruno Picavet, Dominique Froissart, Michel Loirette, Brigitte Costa, Adéla Cauchois, Tan Dat Nguyen
Pages: 921-925
Published online on: 01 July 2003

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Article

Improvement of 10-year survival by Japanese radical lymph node dissection in patients with Dukes' B and C colorectal cancer: A 17-year retrospective study

Masaya Mukai, Isao Ito, Sayuri Mukoyama, Takayuki Tajima, Yuuki Saito, Hisao Nakasaki, Shinkichi Sato, Hiroyasu Makuuchi
Pages: 927-934
Published online on: 01 July 2003

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Article

Hypermethylation of the CDKN2A gene in colorectal cancer is associated with shorter survival

Kazuya Maeda, Kazuyuki Kawakami, Yoshinori Ishida, Kaname Ishiguro, Kenji Omura, Go Watanabe
Pages: 935-938
Published online on: 01 July 2003

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Article

Lymphagenesis correlates with expression of vascular endothelial growth factor-C in colorectal cancer

Masakazu Ohno, Takeshi Nakamura, Yukihiro Kunimoto, Koji Nishimura, Cheng Chung-Kang, Yoshikazu Kuroda
Pages: 939-943
Published online on: 01 July 2003

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Article

Differentiation of benign and malignant breast tumors using Doppler spectral parameters including acceleration time index

Kazunari Mesaki, Naofumi Hisa, Kei Kubota, Nobuaki Hisa, Yasuhiro Ogawa, Shoji Yoshida
Pages: 945-950
Published online on: 01 July 2003

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Article

A feasibility study of paclitaxel and carboplatin therapy in Japanese patients with epithelial ovarian cancer

Yuji Takei, Mitsuaki Suzuki, Michitaka Ohwada, Yasushi Saga, Takahiro Kohno, Shizuo Machida, Ikuo Sato
Pages: 951-955
Published online on: 01 July 2003

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Article

Extracellular matrix remodeling may predominate over hepatocyte injury in hepatocellular carcinoma development

Hitoshi Yoshiji, Shigeki Kuriyama, Junichi Yoshii, Yasuhide Ikenaka, Ryuichi Noguchi, Koji Yanase, Tadashi Namisaki, Masaharu Yamazaki, Hirohisa Tsujinoue, Hiroo Imazu, Hiroshi Fukui
Pages: 957-962
Published online on: 01 July 2003

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Article

Genetic detection for hematogenous micrometastasis in patients with various types of malignant tumors using Uroplakin II derived primers in polymerase chain reaction

Hiroyuki Hirata, Hisashi Hisatomi, Mutsushi Kawakita, Kumi Nagao, Shigeki Yamamoto, Kazumasa Hikiji, Takaaki Nakamoto, Hiroshi Harasawa, Noboru Kaneko, Tadashi Matsuda, Masahiro Yamamoto, Taichi Kanamaru
Pages: 963-966
Published online on: 01 July 2003

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Article

Influence of platelet-derived endothelial cell growth factor/thymidine phosphorylase on the cell cycle in head and neck squamous cell carcinoma in vitro

Hideki Igawa, Shigeharu Fujieda, Yuichi Kimura, Chizuru Sugimoto, Nobuyuki Tanaka, Toshio Ohtsubo, Yasushi Kato, Hitoshi Saito
Pages: 967-971
Published online on: 01 July 2003

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Article

Induction of apoptosis by fenretinide in tumor cell lines correlates with DLX2, DLX3 and DLX4 gene expression

Nicoletta Ferrari, Laura Paleari, Giulio L. Palmisano, Paolo Tammaro, Giovanni Levi, Adriana Albini, Claudio Brigati
Pages: 973-977
Published online on: 01 July 2003

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Article

Down-regulation of nitric oxide production by droloxifene and toremifene in human breast cancer cells

J. H.J. Martin, A. Symonds, S. Chohan
Pages: 979-984
Published online on: 01 July 2003

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Article

Thin-section CT evaluation and pathologic correlation of therapeutic effect of neoadjuvant chemotherapy for axillary lymph nodes of clinically node-positive breast cancer patients

Yasuhiro Ogawa, Akihito Nishioka, Tohru Nishigawa, Kei Kubota, Shinji Kariya, Shoji Yoshida, Yosuke Tanaka, Toshiaki Moriki, Naoshige Tochika
Pages: 985-989
Published online on: 01 July 2003

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Article

High serum soluble E-selectin levels are associated with postoperative haematogenic recurrence in esophageal squamous cell carcinoma patients

Yutaka Shimada, Masato Maeda, Go Watanabe, Masayuki Imamura
Pages: 991-995
Published online on: 01 July 2003

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Article

Negative hMSH2 protein expression in pancreatic carcinoma may predict a better prognosis of patients

Bunzo Nakata, Yan Qing Wang, Masakazu Yashiro, Masaichi Ohira, Tetsuro Ishikawa, Hiroji Nishino, Shuichi Seki, Kosei Hirakawa
Pages: 997-1000
Published online on: 01 July 2003

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Article

Effect of hepatocyte growth factor on invasion of prostate cancer cell lines

Yasuyoshi Fujiuchi, Osamu Nagakawa, Koji Murakami, Hideki Fuse, Ikuo Saiki
Pages: 1001-1006
Published online on: 01 July 2003

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Article

Membranous lipodystrophy (Nasu-Hakola disease) presenting an unusually benign clinical course

Kumiko Haruta, Shunji Matsunaga, Hiroshi Ito, Kyoji Hayashi, Masahiro Yokouchi, Toshiyuki Onishi, Setsuro Komiya
Pages: 1007-1010
Published online on: 01 July 2003

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Article

In vitro demonstration of breast cancer tumor cell sub-populations based on interleukin-1/tumor necrosis factor induction of interleukin-8 expression

Alexander G. Pantschenko, Irina Pushkar, Lauri J. Miller, Yan Ping Wang, Kathleen Anderson, Ziv Peled, Scott H. Kurtzman, Donald L. Kreutzer
Pages: 1011-1017
Published online on: 01 July 2003

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Article

Human mast cells induce caspase-independent DNA fragmentation in leukemic T cells

Sandra J. Gallagher, Jean S. Marshall, David W. Hoskin
Pages: 1019-1023
Published online on: 01 July 2003

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Article

The mouse mammary tumor virus-like env gene sequence is not detectable in breast cancer tissue of Austrian patients

Armin Witt, Beda Hartmann, Erika Marton, Robert Zeillinger, Martin Schreiber, Ernst Kubista
Pages: 1025-1029
Published online on: 01 July 2003

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Article

Frequent death-associated protein-kinase promoter hypermethylation in brain metastases of solid tumors

Pilar Gonzalez-Gomez, M. Josefa Bello, M. Eva Alonso, Jesus Lomas, Dolores Arjona, Cinthia Amiñoso, Jose M. De Campos, Alberto Isla, Manuel Gutierrez, Juan A. Rey
Pages: 1031-1033
Published online on: 01 July 2003

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Article

Genetic characterization of lung metastases in renal cell carcinoma

Kerstin Junker, Jörg Sänger, Andreas Schmidt, Winfried Hindermann, Norbert Presselt, Herry Helfritzsch, Joerg Schubert
Pages: 1035-1038
Published online on: 01 July 2003

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Article

BAT-26 microsatellite instability does not correlate with the loss of hMLH1 and hMSH2 protein expression in sporadic endometrial cancers

Roman Miturski, Michal Bogusiewicz, Rafal Tarkowski, Carmella Ciotta, Margherita Bignami, Dominique Burnouf, Jerzy A. Jakowicki
Pages: 1039-1043
Published online on: 01 July 2003

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Article

Expression status of Pin1 and cyclins in oral squamous cell carcinoma: Pin1 correlates with Cyclin D1 mRNA expression and clinical significance of cyclins

Hitoshi Miyashita, Takafumi Uchida, Shiro Mori, Seishi Echigo, Katutoshi Motegi
Pages: 1045-1048
Published online on: 01 July 2003

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Article

Specific cytoskeleton changes during apoptosis accompanying induced differentiation of HL-60 myeloid leukemia cells

Renata Veselská, Karel Zitterbart, Sarka Jelínková, Jakub Neradil, Augustin Svoboda
Pages: 1049-1058
Published online on: 01 July 2003

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Article

Epstein-Barr virus-associated gastric carcinoma in Cali, Colombia

Edwin Carrascal, Chihaya Koriyama, Suminori Akiba, Oscar Tamayo, Tetsuhiko Itoh, Yoshito Eizuru, Felipe Garcia, Mauricio Sera, Gabriel Carrasquilla, Maria B. Piazuelo, Luisa Florez, Juan C. Bravo
Pages: 1059-1062
Published online on: 01 July 2003

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Exploring the role of disulfidptosis‑related signatures in immune microenvironment, prognosis and therapeutic strategies of cholangiocarcinoma

Yue Chen, Jun Wu, Danxia Zhu, Lu Jiang, Jian Wang, Dachuan Zhang, Wenting He
Article Number: 37
Published online on: 02 January 2026

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Correction Open Access

[Corrigendum] Isolinderalactone enhances the inhibition of SOCS3 on STAT3 activity by decreasing miR‑30c in breast cancer

Meng-Chi Yen, Ying-Chu Shih, Ya-Ling Hsu, En-Shyh Lin, Yi-Shiuan Lin, Eing-Mei Tsai, Ya-Wen Ho, Ming-Feng Hou, Po-Lin Kuo
Article Number: 36
Published online on: 22 December 2025

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Article Open Access

Hypoxia‑mediated Krebs von den Lungen‑6 expression in breast cancer: Implications for tumor invasion and metastasis

Taisei Ichihara, Yoshihiro Hayashi, Takuya Sato, Mitsuko Iguchi, Makoto Toi, Hironaga Satake, Ichiro Murakami
Article Number: 35
Published online on: 19 December 2025

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Retraction Open Access

[Retracted] β‑elemene decreases cell invasion by upregulating E‑cadherin expression in MCF‑7 human breast cancer cells

Xian Zhang, Yang Zhang, Yinghua Li
Article Number: 34
Published online on: 18 December 2025

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Review Open Access

Research progress on the regulation of ferroptosis in NPC (Review)

Shuai Bai, Yanjie Guo, Jingling Qiang, Qiangfang Dai, Yanling Yang
Article Number: 33
Published online on: 18 December 2025

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Retraction Open Access

[Retracted] Platelet‑derived growth factor BB mediates the glioma‑induced migration of bone marrow‑derived mesenchymal stem cells by promoting the expression of vascular cell adhesion molecule‑1 through the PI3K, P38 MAPK and NF‑κB pathways

Yi Hu, Peng Cheng, Jiang-Chun Ma, Yi-Xue Xue, Yun-Hui Liu
Article Number: 32
Published online on: 08 December 2025

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Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício De Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑De‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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