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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2004 Volume 12 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

CD40 expression in prostate cancer: A potential diagnostic and therapeutic molecule

D. H. Palmer, S. A. Hussain, R. Ganesan, P. W. Cooke, D. M.A. Wallace, L. S. Young, N. D. James
Pages: 679-682
Published online on: 01 October 2004

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Article

Anti-angiogenic mechanisms and efficacy of the low molecular weight heparin, tinzaparin: Anti-cancer efficacy

Shaker A. Mousa, Seema Mohamed
Pages: 683-688
Published online on: 01 October 2004

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Article

Inhibition of mammary gland tumors by short-term treatment of estradiol-3-benzoate associated with down-regulation of estrogen receptor ERα and ERβ

Jin Seok Kang, Seyl Kim, Jeong-Hwan Che, Ki Taek Nam, Dae Joong Kim, Dong Deuk Jang, Ki-Hwa Yang
Pages: 689-693
Published online on: 01 October 2004

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Article

Estrogen receptor α and β, progesterone receptor, pS2 and HER-2/neu expression delineate different subgroups in ductal carcinoma in situ of the breast

Achim Rody, Raihanatou Diallo, Christopher Poremba, Regina Speich, Pia Wuelfing, Stephen Kissler, Christine Solbach, Ludwig Kiesel, Christian Jackisch
Pages: 695-699
Published online on: 01 October 2004

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Article

Gene regulation by phorbol 12-myristate 13-acetate in MCF-7 and MDA-MB-231, two breast cancer cell lines exhibiting highly different phenotypes

M. Lacroix, B. Haibe-Kains, B. Hennuy, J. F. Laes, F. Lallemand, I. Gonze, F. Cardoso, M. Piccart, G. Leclercq, C. Sotiriou
Pages: 701-707
Published online on: 01 October 2004

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Article

Synergistic effects of androgen and estrogen on the mouse uterus and mammary gland

Jian Zhang, Yibin Sun, Yunhai Liu, Yi Sun, Dezhong Joshua Liao
Pages: 709-716
Published online on: 01 October 2004

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Article

Expression spectra of matrix metalloproteinases in metastatic non-small cell lung cancer

Torng-Sen Lin, Shiow-Her Chiou, Liang-Shun Wang, Hsuan-Hua Huang, Shu-Fen Chiang, Alex Y.H. Shih, Ya-Lin Chen, Chih-Yi Chen, Chung-Ping Hsu, Nan-Yung Hsu, Ming-Chih Chou, Shou-Jen Kuo, Kuan-Chih Chow
Pages: 717-723
Published online on: 01 October 2004

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Article

Recognition of Epstein-Barr virus-associated gastric carcinoma cells by cytotoxic T lymphocytes induced in vitro with autologous lymphoblastoid cell line and LMP2-derived, HLA-A24-restricted 9-mer peptide

Kaori Okugawa, Tsuyoshi Itoh, Ichiro Kawashima, Kazutoh Takesako, Osam Mazda, Ikuei Nukaya, Yutaro Yano, Yoshiki Yamamoto, Hisakazu Yamagishi, Yuji Ueda
Pages: 725-731
Published online on: 01 October 2004

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Article

Tissue distribution of Thorotrast and role of internal irradiation in carcinogenesis

Kyoko Yamasaki, Aiichi Yamasaki, Mitsuo Tosaki, Yasuto Isozumi, Hiroshi Hiai
Pages: 733-738
Published online on: 01 October 2004

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Article

Hyaluronan synthase expression in ovarian cancer

Hiromitsu Yabushita, Mari Noguchi, Tameko Kishida, Kanako Fusano, Yasuyuki Noguchi, Naoki Itano, Koji Kimata, Masayoshi Noguchi
Pages: 739-743
Published online on: 01 October 2004

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Article

Predicting the recurrence/metastasis of stage I and II breast cancer without lymph node metastasis

Masaya Mukai, Shinkichi Sato, Tomomi Kimura, Nobukazu Komatsu, Hiromi Ninomiya, Hisao Nakasaki, Kyouji Ogoshi, Hiroyasu Makuuchi
Pages: 745-748
Published online on: 01 October 2004

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Article

Fas ligand expression in human pancreatic cancer

Tetsuo Ohta, Ayman Elnemr, Hirohisa Kitagawa, Masato Kayahara, Hiroyuki Takamura, Takashi Fujimura, Gen-Ichi Nishimura, Koichi Shimizu, Shuang-Qin Yi, Koichi Miwa
Pages: 749-754
Published online on: 01 October 2004

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Article

Antioxidative response for nitric oxide production in breast carcinoma

Peeter Karihtala, Vuokko L. Kinnula, Ylermi Soini
Pages: 755-759
Published online on: 01 October 2004

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Article

Analysis of the production efficiency and titration of various recombinant adeno-associated viruses

Young Ran Nam, Sung Jin Kim, Boyoung Lee, Jin Woo Chang, Chul-Hyen Joo, Yoo Kyum Kim, Heuiran Lee
Pages: 761-766
Published online on: 01 October 2004

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Article

Hearing function in soft tissue sarcoma patients after treatment with carboplatin: A report from the Late Effects Surveillance System

W. Stöhr, T. Langer, A. Kremers, I. Brecht, J. Treuner, A. Dinnesen, J. D. Beck
Pages: 767-771
Published online on: 01 October 2004

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Article

Risk for K-ras gene mutations in smoking-induced lung cancer is associated with cytochrome P4501A1 and glutathione S-transferase μ1 polymorphisms

Naotaka Noda, Daisuke Matsuzoe, Toshikazu Konno, Katsunobu Kawahara, Yuichi Yamashita, Takayuki Shirakusa
Pages: 773-779
Published online on: 01 October 2004

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Article

Aberrant methylation of RASSF4/AD037 in nasopharyngeal carcinoma

Lillian Shuk-Nga Chow, Kwok-Wai Lo, Joseph Kwong, Albert Yue-Hang Wong, Dolly P. Huang
Pages: 781-787
Published online on: 01 October 2004

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Article

Loss of heterozygosity on chromosome 10q associated with malignancy and prognosis in astrocytic tumors, and discovery of novel loss regions

Shigeru Daido, Soichiro Takao, Takashi Tamiya, Yasuhiro Ono, Kinya Terada, Sachio Ito, Mamoru Ouchida, Isao Date, Takashi Ohmoto, Kenji Shimizu
Pages: 789-795
Published online on: 01 October 2004

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Article

1-hexylcarbamoyl-5-fluorouracil + cyclophosphamide + tamoxifen versus CMF + tamoxifen in women with lymph node-positive breast cancer after primary surgery: A randomized controlled trial

Takeshi Tominaga, Morihiko Kimura, Taro Asaga, Minoru Yoshida, Hiroharu Awane, Hiroki Koyama, Yuichi Takatsuka, Syosyu Mitsuyama, Tadashi Ikeda, Masami Ogita, Hideaki Aoyama, Muneaki Sano, Rikiya Abe, Tsunehiro Nishi, Tomio Wada, Makoto Danno, Masakazu Toi, Shigemitsu Takashima
Pages: 797-803
Published online on: 01 October 2004

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Article

Hypermethylation of the RASSF1A tumor suppressor gene in Japanese clear cell renal cell carcinoma

Kenji Tokinaga, Heiwa Okuda, Asuka Nomura, Shingo Ashida, Mutsuo Furihata, Taro Shuin
Pages: 805-810
Published online on: 01 October 2004

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Article

Decreased expression of the candidate tumor suppressor gene ING1 is associated with poor prognosis in advanced neuroblastomas

Masato Takahashi, Toshinori Ozaki, Satoru Todo, Akira Nakagawara
Pages: 811-816
Published online on: 01 October 2004

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Article

Vascular endothelial growth factor concentrations in the plasma-activated platelets rich (P-APR) of healthy controls and colorectal cancer patients

Girolamo Ranieri, Maria Coviello, Rosa Patruno, Paolo Valerio, Domenico Martino, Pietro Milella, Vittorio Catalano, Francesco Scotto, Antonella De Ceglie, Michele Quaranta, Domenico Ribatti, Antonio Pellecchia
Pages: 817-820
Published online on: 01 October 2004

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Article

Expression of poly(ADP-ribose) polymerase in human hepatocellular carcinoma and analysis of biopsy specimens obtained under sonographic guidance

Shirou Shimizu, Fumio Nomura, Takeshi Tomonaga, Masahiko Sunaga, Masatoshi Noda, Masaaki Ebara, Hiromitsu Saisho
Pages: 821-825
Published online on: 01 October 2004

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Article

Excision repair cross complementing 3 expression is involved in patient prognosis and tumor progression in esophageal cancer

Yukio Terashita, Hideyuki Ishiguro, Nobuhiro Haruki, Hironori Sugiura, Tadashi Tanaka, Masahiro Kimura, Noriyuki Shinoda, Yoshiyuki Kuwabara, Yoshitaka Fujii
Pages: 827-831
Published online on: 01 October 2004

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Article

Expression of endothelial nitric oxide synthase is induced by estrogen with glycogen synthase 3β phosphorylation in MCF-7 cells

Kaname Nakatani, Junichi Horinouchi, Yasuyoshi Yabu, Hideo Wada, Tsutomu Nobori
Pages: 833-836
Published online on: 01 October 2004

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Article

Differential expression of integrin subunits in DU-145/AR prostate cancer cells

Osamu Nagakawa, Takuya Akashi, Yoshihiro Hayakawa, Akira Junicho, Keiichi Koizumi, Yasuyoshi Fujiuchi, Yuzo Furuya, Tadashi Matsuda, Hideki Fuse, Ikuo Saiki
Pages: 837-841
Published online on: 01 October 2004

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Article

Synergistic induction of in vivo angiogenesis by the combination of insulin-like growth factor-II and epidermal growth factor

You Mie Lee, Myung-Ho Bae, Ok-Hee Lee, Eun-Joung Moon, Chang-Kiu Moon, Woo-Ho Kim, Kyu-Won Kim
Pages: 843-848
Published online on: 01 October 2004

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Article

Overexpression of Ang-2 mRNA in non-small cell lung cancer: Association with angiogenesis and poor prognosis

Iwao Takanami
Pages: 849-853
Published online on: 01 October 2004

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Article

Low doses of subcutaneous interleukin-2 plus interferon-α do not induce thyroid function alterations in advanced renal cell carcinoma patients

Andrea Sartore-Bianchi, Alessandra Soriani, Raffaella Mattioni, Augusto Vaglio, Carlo Buzio, Camillo Porta
Pages: 855-859
Published online on: 01 October 2004

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Article

Molecular analysis of PinX1 in human hepatocellular carcinoma

Bong-Kyeong Oh, Kwang Jo Chae, Chanil Park, Young Nyun Park
Pages: 861-866
Published online on: 01 October 2004

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Article

Health-related quality of life in patients with testicular cancer: A comparative analysis according to therapeutic modalities

Hideaki Miyake, Mototsugu Muramaki, Hiroshi Eto, Sadao Kamidono, Isao Hara
Pages: 867-870
Published online on: 01 October 2004

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Article

Cytotoxic T-cell immunity against telomerase reverse transcriptase in colorectal cancer patients

Liviu V. Titu, Ruth L. Loveday, Leigh A. Madden, Lynn Cawkwell, John R. Monson, John Greenman
Pages: 871-876
Published online on: 01 October 2004

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Article

Chemotherapy and immunotherapy of tumours induced by gene-modified HPV16-transformed cells

Eva Sobotková, Martina Dusková, Michal Smahel, Vladimir Holán, Olga Janousková, Vladimir Vonka
Pages: 877-883
Published online on: 01 October 2004

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Article

Plasma from pregnant rats has anti-tumoural activity

Neus Carbó, Francisco J. López-Soriano, Josep M. Argilés
Pages: 885-887
Published online on: 01 October 2004

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Article

Radiosensitization of a human soft tissue sarcoma cell line US8-93 (mt-p53) with the oxidizer sodium peroxodisulfate

Matthias Bache, Jürgen Dunst, Frank Matschiner, Sybille Matschiner, Matthias Kappler, Frank Bartel, Hannelore Schmidt, Alexander Berghaus, Helge Taubert
Pages: 889-893
Published online on: 01 October 2004

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Article

Hypoxic antiblastic stop-flow limb perfusion: Clinical outcome and pharmacokinetic findings of a novel treatment for in transit melanoma metastases

Pierluigi Pilati, Simone Mocellin, Diego Miotto, Claudio Fittà, Dario Casara, Carlo Ori, Romano Scalerta, Donato Nitti, Mario Lise, Carlo Riccardo Rossi
Pages: 895-901
Published online on: 01 October 2004

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Article

The HER2/Grb2/Akt pathway regulates the DNA binding activity of AP-1 in breast cancer cells

Edgar Mendoza-Gamboa, Doris R. Siwak, Ana M. Tari
Pages: 903-908
Published online on: 01 October 2004

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Article

In situ gene expression of urokinase-type plasminogen activator and its receptor in transitional cell carcinoma of the human bladder

Venugopal Bhuvarahamurthy, Joerg Schroeder, Carsten Denkert, Glen Kristiansen, Dietmar Schnorr, Stefan A. Loening, Klaus Jung, Andrea Staack
Pages: 909-913
Published online on: 01 October 2004

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Article

Prognostic value of Topoisomerase II in female breast cancer

Rumelia Koren, Lea Rath-Wolfson, Edward Ram, Ofer Ben Itzhac, Benny Schachter, Baruch Klein, Rivka Gal, Zeev Dreznik
Pages: 915-919
Published online on: 01 October 2004

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Article

GST-pi expression correlates with oxidative stress and apoptosis in breast cancer

Jingxiang Huang, Puay Hoon Tan, Benny Kwong Huat Tan, Boon Huat Bay
Pages: 921-925
Published online on: 01 October 2004

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Article

Leucovorin and fluorouracil vs levamisole and fluorouracil as adjuvant chemotherapy in rectal cancer

N. Tsavaris, K. Gennatas, C. Kosmas, H. M. Skopelitis, P. Gouveris, A. Dimitrakopoulos, M. Zacharakis, G. Kouraklis, J. Vasiliou, E. Felekouras, D. Voros, G. Zografos, M. Balafouta, M. Paraskevaidis, M. Safioleas, K. Fotiadis, G. Papastratis, G. Karatzas, E. Papalambros
Pages: 927-932
Published online on: 01 October 2004

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Article

Characterization of RUSC1 and RUSC2 genes in silico

Masuko Katoh, Masaru Katoh
Pages: 933-938
Published online on: 01 October 2004

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Article

Identification and characterization of CDC50A, CDC50B and CDC50C genes in silico

Yuriko Katoh, Masaru Katoh
Pages: 939-943
Published online on: 01 October 2004

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Article

Outcome of patients with lung cancer detected incidentally

Maki Kanashiki, Hiroaki Satoh, Hiroichi Ishikawa, Morio Ohtsuka, Kiyohisa Sekizawa
Pages: 945-948
Published online on: 01 October 2004

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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