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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2004 Volume 12 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

CD40 expression in prostate cancer: A potential diagnostic and therapeutic molecule

D. H. Palmer, S. A. Hussain, R. Ganesan, P. W. Cooke, D. M.A. Wallace, L. S. Young, N. D. James
Pages: 679-682
Published online on: 01 October 2004

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Article

Anti-angiogenic mechanisms and efficacy of the low molecular weight heparin, tinzaparin: Anti-cancer efficacy

Shaker A. Mousa, Seema Mohamed
Pages: 683-688
Published online on: 01 October 2004

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Article

Inhibition of mammary gland tumors by short-term treatment of estradiol-3-benzoate associated with down-regulation of estrogen receptor ERα and ERβ

Jin Seok Kang, Seyl Kim, Jeong-Hwan Che, Ki Taek Nam, Dae Joong Kim, Dong Deuk Jang, Ki-Hwa Yang
Pages: 689-693
Published online on: 01 October 2004

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Article

Estrogen receptor α and β, progesterone receptor, pS2 and HER-2/neu expression delineate different subgroups in ductal carcinoma in situ of the breast

Achim Rody, Raihanatou Diallo, Christopher Poremba, Regina Speich, Pia Wuelfing, Stephen Kissler, Christine Solbach, Ludwig Kiesel, Christian Jackisch
Pages: 695-699
Published online on: 01 October 2004

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Article

Gene regulation by phorbol 12-myristate 13-acetate in MCF-7 and MDA-MB-231, two breast cancer cell lines exhibiting highly different phenotypes

M. Lacroix, B. Haibe-Kains, B. Hennuy, J. F. Laes, F. Lallemand, I. Gonze, F. Cardoso, M. Piccart, G. Leclercq, C. Sotiriou
Pages: 701-707
Published online on: 01 October 2004

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Article

Synergistic effects of androgen and estrogen on the mouse uterus and mammary gland

Jian Zhang, Yibin Sun, Yunhai Liu, Yi Sun, Dezhong Joshua Liao
Pages: 709-716
Published online on: 01 October 2004

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Article

Expression spectra of matrix metalloproteinases in metastatic non-small cell lung cancer

Torng-Sen Lin, Shiow-Her Chiou, Liang-Shun Wang, Hsuan-Hua Huang, Shu-Fen Chiang, Alex Y.H. Shih, Ya-Lin Chen, Chih-Yi Chen, Chung-Ping Hsu, Nan-Yung Hsu, Ming-Chih Chou, Shou-Jen Kuo, Kuan-Chih Chow
Pages: 717-723
Published online on: 01 October 2004

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Article

Recognition of Epstein-Barr virus-associated gastric carcinoma cells by cytotoxic T lymphocytes induced in vitro with autologous lymphoblastoid cell line and LMP2-derived, HLA-A24-restricted 9-mer peptide

Kaori Okugawa, Tsuyoshi Itoh, Ichiro Kawashima, Kazutoh Takesako, Osam Mazda, Ikuei Nukaya, Yutaro Yano, Yoshiki Yamamoto, Hisakazu Yamagishi, Yuji Ueda
Pages: 725-731
Published online on: 01 October 2004

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Article

Tissue distribution of Thorotrast and role of internal irradiation in carcinogenesis

Kyoko Yamasaki, Aiichi Yamasaki, Mitsuo Tosaki, Yasuto Isozumi, Hiroshi Hiai
Pages: 733-738
Published online on: 01 October 2004

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Article

Hyaluronan synthase expression in ovarian cancer

Hiromitsu Yabushita, Mari Noguchi, Tameko Kishida, Kanako Fusano, Yasuyuki Noguchi, Naoki Itano, Koji Kimata, Masayoshi Noguchi
Pages: 739-743
Published online on: 01 October 2004

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Article

Predicting the recurrence/metastasis of stage I and II breast cancer without lymph node metastasis

Masaya Mukai, Shinkichi Sato, Tomomi Kimura, Nobukazu Komatsu, Hiromi Ninomiya, Hisao Nakasaki, Kyouji Ogoshi, Hiroyasu Makuuchi
Pages: 745-748
Published online on: 01 October 2004

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Article

Fas ligand expression in human pancreatic cancer

Tetsuo Ohta, Ayman Elnemr, Hirohisa Kitagawa, Masato Kayahara, Hiroyuki Takamura, Takashi Fujimura, Gen-Ichi Nishimura, Koichi Shimizu, Shuang-Qin Yi, Koichi Miwa
Pages: 749-754
Published online on: 01 October 2004

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Article

Antioxidative response for nitric oxide production in breast carcinoma

Peeter Karihtala, Vuokko L. Kinnula, Ylermi Soini
Pages: 755-759
Published online on: 01 October 2004

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Article

Analysis of the production efficiency and titration of various recombinant adeno-associated viruses

Young Ran Nam, Sung Jin Kim, Boyoung Lee, Jin Woo Chang, Chul-Hyen Joo, Yoo Kyum Kim, Heuiran Lee
Pages: 761-766
Published online on: 01 October 2004

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Article

Hearing function in soft tissue sarcoma patients after treatment with carboplatin: A report from the Late Effects Surveillance System

W. Stöhr, T. Langer, A. Kremers, I. Brecht, J. Treuner, A. Dinnesen, J. D. Beck
Pages: 767-771
Published online on: 01 October 2004

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Article

Risk for K-ras gene mutations in smoking-induced lung cancer is associated with cytochrome P4501A1 and glutathione S-transferase μ1 polymorphisms

Naotaka Noda, Daisuke Matsuzoe, Toshikazu Konno, Katsunobu Kawahara, Yuichi Yamashita, Takayuki Shirakusa
Pages: 773-779
Published online on: 01 October 2004

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Article

Aberrant methylation of RASSF4/AD037 in nasopharyngeal carcinoma

Lillian Shuk-Nga Chow, Kwok-Wai Lo, Joseph Kwong, Albert Yue-Hang Wong, Dolly P. Huang
Pages: 781-787
Published online on: 01 October 2004

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Article

Loss of heterozygosity on chromosome 10q associated with malignancy and prognosis in astrocytic tumors, and discovery of novel loss regions

Shigeru Daido, Soichiro Takao, Takashi Tamiya, Yasuhiro Ono, Kinya Terada, Sachio Ito, Mamoru Ouchida, Isao Date, Takashi Ohmoto, Kenji Shimizu
Pages: 789-795
Published online on: 01 October 2004

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Article

1-hexylcarbamoyl-5-fluorouracil + cyclophosphamide + tamoxifen versus CMF + tamoxifen in women with lymph node-positive breast cancer after primary surgery: A randomized controlled trial

Takeshi Tominaga, Morihiko Kimura, Taro Asaga, Minoru Yoshida, Hiroharu Awane, Hiroki Koyama, Yuichi Takatsuka, Syosyu Mitsuyama, Tadashi Ikeda, Masami Ogita, Hideaki Aoyama, Muneaki Sano, Rikiya Abe, Tsunehiro Nishi, Tomio Wada, Makoto Danno, Masakazu Toi, Shigemitsu Takashima
Pages: 797-803
Published online on: 01 October 2004

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Article

Hypermethylation of the RASSF1A tumor suppressor gene in Japanese clear cell renal cell carcinoma

Kenji Tokinaga, Heiwa Okuda, Asuka Nomura, Shingo Ashida, Mutsuo Furihata, Taro Shuin
Pages: 805-810
Published online on: 01 October 2004

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Article

Decreased expression of the candidate tumor suppressor gene ING1 is associated with poor prognosis in advanced neuroblastomas

Masato Takahashi, Toshinori Ozaki, Satoru Todo, Akira Nakagawara
Pages: 811-816
Published online on: 01 October 2004

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Article

Vascular endothelial growth factor concentrations in the plasma-activated platelets rich (P-APR) of healthy controls and colorectal cancer patients

Girolamo Ranieri, Maria Coviello, Rosa Patruno, Paolo Valerio, Domenico Martino, Pietro Milella, Vittorio Catalano, Francesco Scotto, Antonella De Ceglie, Michele Quaranta, Domenico Ribatti, Antonio Pellecchia
Pages: 817-820
Published online on: 01 October 2004

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Article

Expression of poly(ADP-ribose) polymerase in human hepatocellular carcinoma and analysis of biopsy specimens obtained under sonographic guidance

Shirou Shimizu, Fumio Nomura, Takeshi Tomonaga, Masahiko Sunaga, Masatoshi Noda, Masaaki Ebara, Hiromitsu Saisho
Pages: 821-825
Published online on: 01 October 2004

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Article

Excision repair cross complementing 3 expression is involved in patient prognosis and tumor progression in esophageal cancer

Yukio Terashita, Hideyuki Ishiguro, Nobuhiro Haruki, Hironori Sugiura, Tadashi Tanaka, Masahiro Kimura, Noriyuki Shinoda, Yoshiyuki Kuwabara, Yoshitaka Fujii
Pages: 827-831
Published online on: 01 October 2004

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Article

Expression of endothelial nitric oxide synthase is induced by estrogen with glycogen synthase 3β phosphorylation in MCF-7 cells

Kaname Nakatani, Junichi Horinouchi, Yasuyoshi Yabu, Hideo Wada, Tsutomu Nobori
Pages: 833-836
Published online on: 01 October 2004

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Article

Differential expression of integrin subunits in DU-145/AR prostate cancer cells

Osamu Nagakawa, Takuya Akashi, Yoshihiro Hayakawa, Akira Junicho, Keiichi Koizumi, Yasuyoshi Fujiuchi, Yuzo Furuya, Tadashi Matsuda, Hideki Fuse, Ikuo Saiki
Pages: 837-841
Published online on: 01 October 2004

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Article

Synergistic induction of in vivo angiogenesis by the combination of insulin-like growth factor-II and epidermal growth factor

You Mie Lee, Myung-Ho Bae, Ok-Hee Lee, Eun-Joung Moon, Chang-Kiu Moon, Woo-Ho Kim, Kyu-Won Kim
Pages: 843-848
Published online on: 01 October 2004

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Article

Overexpression of Ang-2 mRNA in non-small cell lung cancer: Association with angiogenesis and poor prognosis

Iwao Takanami
Pages: 849-853
Published online on: 01 October 2004

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Article

Low doses of subcutaneous interleukin-2 plus interferon-α do not induce thyroid function alterations in advanced renal cell carcinoma patients

Andrea Sartore-Bianchi, Alessandra Soriani, Raffaella Mattioni, Augusto Vaglio, Carlo Buzio, Camillo Porta
Pages: 855-859
Published online on: 01 October 2004

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Article

Molecular analysis of PinX1 in human hepatocellular carcinoma

Bong-Kyeong Oh, Kwang Jo Chae, Chanil Park, Young Nyun Park
Pages: 861-866
Published online on: 01 October 2004

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Article

Health-related quality of life in patients with testicular cancer: A comparative analysis according to therapeutic modalities

Hideaki Miyake, Mototsugu Muramaki, Hiroshi Eto, Sadao Kamidono, Isao Hara
Pages: 867-870
Published online on: 01 October 2004

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Article

Cytotoxic T-cell immunity against telomerase reverse transcriptase in colorectal cancer patients

Liviu V. Titu, Ruth L. Loveday, Leigh A. Madden, Lynn Cawkwell, John R. Monson, John Greenman
Pages: 871-876
Published online on: 01 October 2004

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Article

Chemotherapy and immunotherapy of tumours induced by gene-modified HPV16-transformed cells

Eva Sobotková, Martina Dusková, Michal Smahel, Vladimir Holán, Olga Janousková, Vladimir Vonka
Pages: 877-883
Published online on: 01 October 2004

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Article

Plasma from pregnant rats has anti-tumoural activity

Neus Carbó, Francisco J. López-Soriano, Josep M. Argilés
Pages: 885-887
Published online on: 01 October 2004

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Article

Radiosensitization of a human soft tissue sarcoma cell line US8-93 (mt-p53) with the oxidizer sodium peroxodisulfate

Matthias Bache, Jürgen Dunst, Frank Matschiner, Sybille Matschiner, Matthias Kappler, Frank Bartel, Hannelore Schmidt, Alexander Berghaus, Helge Taubert
Pages: 889-893
Published online on: 01 October 2004

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Article

Hypoxic antiblastic stop-flow limb perfusion: Clinical outcome and pharmacokinetic findings of a novel treatment for in transit melanoma metastases

Pierluigi Pilati, Simone Mocellin, Diego Miotto, Claudio Fittà, Dario Casara, Carlo Ori, Romano Scalerta, Donato Nitti, Mario Lise, Carlo Riccardo Rossi
Pages: 895-901
Published online on: 01 October 2004

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Article

The HER2/Grb2/Akt pathway regulates the DNA binding activity of AP-1 in breast cancer cells

Edgar Mendoza-Gamboa, Doris R. Siwak, Ana M. Tari
Pages: 903-908
Published online on: 01 October 2004

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Article

In situ gene expression of urokinase-type plasminogen activator and its receptor in transitional cell carcinoma of the human bladder

Venugopal Bhuvarahamurthy, Joerg Schroeder, Carsten Denkert, Glen Kristiansen, Dietmar Schnorr, Stefan A. Loening, Klaus Jung, Andrea Staack
Pages: 909-913
Published online on: 01 October 2004

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Article

Prognostic value of Topoisomerase II in female breast cancer

Rumelia Koren, Lea Rath-Wolfson, Edward Ram, Ofer Ben Itzhac, Benny Schachter, Baruch Klein, Rivka Gal, Zeev Dreznik
Pages: 915-919
Published online on: 01 October 2004

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Article

GST-pi expression correlates with oxidative stress and apoptosis in breast cancer

Jingxiang Huang, Puay Hoon Tan, Benny Kwong Huat Tan, Boon Huat Bay
Pages: 921-925
Published online on: 01 October 2004

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Article

Leucovorin and fluorouracil vs levamisole and fluorouracil as adjuvant chemotherapy in rectal cancer

N. Tsavaris, K. Gennatas, C. Kosmas, H. M. Skopelitis, P. Gouveris, A. Dimitrakopoulos, M. Zacharakis, G. Kouraklis, J. Vasiliou, E. Felekouras, D. Voros, G. Zografos, M. Balafouta, M. Paraskevaidis, M. Safioleas, K. Fotiadis, G. Papastratis, G. Karatzas, E. Papalambros
Pages: 927-932
Published online on: 01 October 2004

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Article

Characterization of RUSC1 and RUSC2 genes in silico

Masuko Katoh, Masaru Katoh
Pages: 933-938
Published online on: 01 October 2004

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Article

Identification and characterization of CDC50A, CDC50B and CDC50C genes in silico

Yuriko Katoh, Masaru Katoh
Pages: 939-943
Published online on: 01 October 2004

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Article

Outcome of patients with lung cancer detected incidentally

Maki Kanashiki, Hiroaki Satoh, Hiroichi Ishikawa, Morio Ohtsuka, Kiyohisa Sekizawa
Pages: 945-948
Published online on: 01 October 2004

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Research progress on plant polysaccharides in the prevention and treatment of tumors (Review)

Jikun Wang, Yihan Wang, Xiwu Zhang
Article Number: 152
Published online on: 26 June 2026

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Article Open Access

PIN1 inhibits ferroptosis in gastric cancer cells by regulating the CPEB1‑GPX4 pathway

Aoran Zeng, Tao Wang, Jie Song, Lili Zhu, Ling Chen, Qi Yuan, Ying Jiang, Ping Zhang, Shengzhong Rong, Jing Wang
Article Number: 151
Published online on: 24 June 2026

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Review Open Access

Tanshinone IIA in breast cancer: Molecular mechanisms, structural optimization and translational challenges (Review)

Xiuxia Li, Linlin Feng
Article Number: 150
Published online on: 23 June 2026

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Retraction Open Access

[Retracted] Kevetrin induces apoptosis in TP53 wild‑type and mutant acute myeloid leukemia cells

Roberta Napolitano, Serena De Matteis, Silvia Carloni, Samantha Bruno, Giulia Abbati, Laura Capelli, Martina Ghetti, Maria Teresa Bochicchio, Chiara Liverani, Laura Mercatali, Daniele Calistri, Antonio Cuneo, Krishna Menon, Gerardo Musuraca, Giovanni Martinelli, Giorgia Simonetti
Article Number: 149
Published online on: 22 June 2026

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Article Open Access

PI3Kδ inhibitor YY‑20394 is effective alone or in combination with Bcl‑2 inhibitor ABT199 in acute myeloid leukemia cells

Yinghua Geng, Lili Zhou, Yan Lou, Jiaqi Chen, Qi Liu, Ji Shen, Yanli Yang, Wenjuan Wu
Article Number: 148
Published online on: 17 June 2026

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Article Open Access

Schisandrin B exhibits anti‑proliferative effects by inducing ferroptosis in pancreatic cancer

Fengjin Li, Jiacai Fu, Xiaowei Lin, Yanting Liu, Lu Yang, Yuxin Li, Tieli Peng, Ling Qi
Article Number: 147
Published online on: 16 June 2026

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Review

Research advances on DKK1 in head and neck squamous cell carcinoma: Linking molecular mechanisms to clinical applications (Review)

Xiaoqian Zhu, Liwei Hong, Weihan Chen, Junjuan Tan, Juju Zhou, Lingya Yang, Yonglin Liu, Tiantian Zhai, Kai Chen
Article Number: 146
Published online on: 16 June 2026

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Article Open Access

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
Article Number: 145
Published online on: 10 June 2026

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Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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Journal Cover
September-2026 Volume 56 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Retraction Open Access

[Retracted] Methylation and intratumoural heterogeneity of 14‑3‑3 σ in oral cancer

Ujjal Kumar Bhawal, Keiichi Tsukinoki, Tomonori Sasahira, Fuyuki Sato, Yusuke Mori, Noriko Muto, Masaru Sugiyama, Hiroki Kuniyasu
Article Number: 160
Published online on: 20 July 2026

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M2‑TAM‑derived exosomal miR‑491‑3p modulates UBE2D3 and promotes the proliferation, migration and invasion of lung cancer cells

Qiang Zhang, Yungang Sun, Yu Zhuang, Shiwei Xu, Mengxu Yao, Siyang Jiao, Qi Wang, Feng Shao, Xiaoying Zhang
Article Number: 159
Published online on: 17 July 2026

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Correction Open Access

[Corrigendum] Emodin attenuated severe acute pancreatitis via the P2X ligand‑gated ion channel 7/NOD‑like receptor protein 3 signaling pathway

Qingkai Zhang, Xufeng Tao, Shilin Xia, Jialin Qu, Huiyi Song, Jianjun Liu, Hailong Li, Dong Shang
Article Number: 158
Published online on: 15 July 2026

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TM6SF2 overexpression suppresses the proliferation and promotes apoptosis of human hepatocellular carcinoma cells

Ziyou Huai, Wanying Xue, Xinxiao Jin, Shiyu Peng, Wenqiang Xu, Shujing Li, Huanfeng Hao, Yuanyuan Wang
Article Number: 157
Published online on: 14 July 2026

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Correction Open Access

[Corrigendum] VDAC upregulation and αTAT1‑mediated α‑tubulin acetylation contribute to tanespimycin‑induced apoptosis in Calu‑1 cells

Qilin Wang, Xiangguo Liu
Article Number: 156
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells

Annamaria Spina, Luca Sorvillo, Emilio Chiosi, Antonietta Esposito, Francesca Di Maiolo, Luigi Sapio, Michele Caraglia, Silvio Naviglio
Article Number: 155
Published online on: 06 July 2026

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Identification of RRM2 as a key regulator of malignant epithelial cells in gastric cancer through single‑cell transcriptomics

Xinzhen Cai, Yun He, Lili Kang, Dongli Zhou, Mengmeng Wang, Tianyu Ma
Article Number: 154
Published online on: 03 July 2026

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Impact of WFDC2 on the biological functions of cervical cancer cells and the regulation of the ERK/NF‑κB signaling pathway

Yanping Zhang, Hongling Zou, Shufeng Deng, Lvling Zou, Mingzhu Xia, Limin Tao
Article Number: 153
Published online on: 01 July 2026

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