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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2008 Volume 19 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Fungal metabolites modulating NF-κB activity: An approach to cancer therapy and chemoprevention (Review)

Roumyana D. Petrova, Abraham Z. Reznick, Solomon P. Wasser, Cvetomir M. Denchev, Eviatar Nevo, Jamal Mahajna
Pages: 299-308
Published online on: 01 February 2008

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Article

Microvessel density and VEGF/VEGF receptor status and their role in sarcomas of the pulmonary artery

Andreas K.A. Gaumann, Gero Schermutzki, Thomas Mentzel, C. James Kirkpatrick, Joerg B. Kriegsmann, Moritz A. Konerding
Pages: 309-318
Published online on: 01 February 2008

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Article

Overexpression of phospho-Akt correlates with phosphorylation of EGF receptor, FKHR and BAD in nasopharyngeal carcinoma

Wai Kien Yip, Vincent Ching Shian Leong, Maizaton Atmadini Abdullah, Suryati Yusoff, Heng Fong Seow
Pages: 319-328
Published online on: 01 February 2008

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Article

Differentiation of human follicular thyroid adenomas from carcinomas by gene expression profiling

Jianming Zhao, Christa Leonard, Ernst Gemsenjäger, Philipp U. Heitz, Holger Moch, Bernhard Odermatt
Pages: 329-337
Published online on: 01 February 2008

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Article

Down-regulation of cobalt-induced HIF-1α expression correlates with cell proliferation and apoptosis in human gastric carcinoma cells

Tonang Dwi Ardyanto, Mitsuhiko Osaki, Yumi Nagahama, Kensaku Yamaga, Noritaka Maeta, Takayuki Tamura, Hisao Ito
Pages: 339-343
Published online on: 01 February 2008

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Article

Increased numbers of endothelial progenitor cells in peripheral blood and tumor specimens in non-small cell lung cancer: A methodological challenge and an ongoing debate on the clinical relevance

Andreas Pircher, Christian Matthias Kähler, Sergej Skvortsov, Margit Dlaska, Gerold Kawaguchi, Thomas Schmid, Eberhard Gunsilius, Wolfgang Hilbe
Pages: 345-352
Published online on: 01 February 2008

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Article

In vitro antiproliferative and antimigratory activity of dasatinib in neuroblastoma and Ewing sarcoma cell lines

Fabio Timeus, Nicoletta Crescenzio, Abderrahim Fandi, Alessandra Doria, Luiselda Foglia, Luca Cordero Di Montezemolo
Pages: 353-359
Published online on: 01 February 2008

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Article

Anti-tumor effects of cimetidine on hepatocellular carcinomas in diethylnitrosamine-treated rats

Koichiro Furuta, Shuichi Sato, Tatsuya Miyake, Eisuke Okamoto, Junichi Ishine, Shunji Ishihara, Yuji Amano, Kyoichi Adachi, Yoshikazu Kinoshita
Pages: 361-368
Published online on: 01 February 2008

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Article

Asynchronous DNA replication detected by fluorescence in situ hybridisation as a possible indicator of genetic damage in human lymphocytes

A. Brás, C. Z. Cotrim, I. Vasconcelos, J. Mexia, A. Léonard, I. Sanzhar, N. Akhmatullina, J. Rueff
Pages: 369-375
Published online on: 01 February 2008

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Article

E-cadherin expression and epidermal growth factor receptor mutation status predict outcome in non-small cell lung cancer patients treated with gefitinib

Akihiko Miyanaga, Akihiko Gemma, Masahiro Ando, Seiji Kosaihira, Rintaro Noro, Yuji Minegishi, Kiyoko Kataoka, Michiya Nara, Tetsuya Okano, Hitoshi Miyazawa, Tomoaki Tanaka, Akinobu Yoshimura, Kunihiko Kobayashi, Hiroshi Iwanami, Koichi Hagiwara, Eitaka Tsuboi, Shoji Kudoh
Pages: 377-383
Published online on: 01 February 2008

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Article Open Access

Expression analysis of VEGFA, FGF2, TGFβ1, EGF and IGF1 in human nasal polyposis

Apostolos Zaravinos, Giannoula Soufla, John Bizakis, Demetrios A. Spandidos
Pages: 385-391
Published online on: 01 February 2008

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Article

Inhibitory effects of the cyclooxygenase-2 inhibitor, etodolac, on colitis-associated tumorigenesis in p53-deficient mice treated with dextran sulfate sodium

Kenichiroh Mukawa, Shigehiko Fujii, Keiichi Tominaga, Naoto Yoshitake, Akihito Abe, Tokuyuki Kono, Akira Sekikawa, Hirokazu Fukui, Kazuhito Ichikawa, Shigeki Tomita, Johji Imura, Yuko Ono, Motoo Shinoda, Hideyuki Hiraishi, Takahiro Fujimori
Pages: 393-399
Published online on: 01 February 2008

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Article

Overexpression of hMSH2 and hMLH1 protein in certain gastric cancers and their surrounding mucosae

Mei Li, Lina Liu, Zhaohui Wang, Lihong Wang, Zhimin Liu, Guowang Xu, Shen Lu
Pages: 401-406
Published online on: 01 February 2008

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Article

DNA methylation and sensitivity to antimetabolites in cancer cell lines

Shin Sasaki, Takashi Kobunai, Joji Kitayama, Hirokazu Nagawa
Pages: 407-412
Published online on: 01 February 2008

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Article

Protective effects of resveratrol on UVB-irradiated HaCaT cells through attenuation of the caspase pathway

Kun Park, Ji-Hye Lee
Pages: 413-417
Published online on: 01 February 2008

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Article

Overexpression of Id-1 protein is a marker in colorectal cancer progression

Zeng-Ren Zhao, Zhi-Yong Zhang, Hong Zhang, Li Jiang, Ming-Wei Wang, Xiao-Feng Sun
Pages: 419-424
Published online on: 01 February 2008

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Article

Differential effects of selective cyclooxygenase-2 inhibitors in inhibiting proliferation and induction of apoptosis in oral squamous cell carcinoma

Seong-Hee Ko, Geun Jun Choi, Ji Hye Lee, Yoon A Han, Soo-Jeong Lim, So Hee Kim
Pages: 425-433
Published online on: 01 February 2008

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Article

Epidermal growth factor receptor and human epidermal growth receptor 2 expression in parotid mucoepidermoid carcinoma: Possible implications for targeted therapy

Jinbiao Shang, Yongjie Shui, Liming Sheng, Kejing Wang, Qiongge Hu, Qichun Wei
Pages: 435-440
Published online on: 01 February 2008

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Article

The proteasome subunit PSMA7 located on the 20q13 amplicon is overexpressed and associated with liver metastasis in colorectal cancer

Xiao-Tong Hu, Wei Chen, Da Wang, Qing-Lan Shi, Fu-Biao Zhang, Yong-Qiang Liao, Mei Jin, Chao He
Pages: 441-446
Published online on: 01 February 2008

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Article

Phase I study of weekly topotecan combined to concurrent external cranial irradiation in adults with glioblastoma multiforme of the brain

H. Varveris, E. Petinelli, J. Stratakis, M. Mazonakis
Pages: 447-455
Published online on: 01 February 2008

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Article

Predictive testing of early cervical pre-cancer by detecting human papillomavirus E6/E7 mRNA in cervical cytologies up to high-grade squamous intraepithelial lesions: Diagnostic and prognostic implications

Alinda D. Varnai, Magdolna Bollmann, Agnes Bankfalvi, Norbert Speich, Christoph Schmitt, Harald Griefingholt, Krisztina Kovács, Christiane Klozoris, Reinhard Bollmann
Pages: 457-465
Published online on: 01 February 2008

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Article

Prognostic implication of SYT-SSX fusion type in synovial sarcoma: A multi-institutional retrospective analysis in Japan

Satoshi Takenaka, Takafumi Ueda, Norifumi Naka, Nobuhito Araki, Nobuyuki Hashimoto, Akira Myoui, Toshifumi Ozaki, Tomitaka Nakayama, Junya Toguchida, Kazuhiro Tanaka, Yukihide Iwamoto, Akihiko Matsumine, Atsumasa Uchida, Makoto Ieguchi, Mitsunori Kaya, Takuro Wada, Ichiro Baba, Ikuo Kudawara, Yasuaki Aoki, Hideki Yoshikawa
Pages: 467-476
Published online on: 01 February 2008

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Article

Metastatic renal cancer and patient survival as a criterion of treatment response

George P. Stathopoulos, John Koutantos, Sotiris K. Rigatos, John Stathopoulos, Spiros Batzios, Christina Batziou
Pages: 477-481
Published online on: 01 February 2008

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Article

Tissue inhibitor of metalloproteinase 2 (TIMP-2) expression in adenocarcinoma pleural effusions

Enrico Giarnieri, Mauro Alderisio, Rita Mancini, Carlo Falasca, Alberto Ricci, Salvatore Mariotta, Maria Rosaria Giovagnoli
Pages: 483-487
Published online on: 01 February 2008

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Article

A three-gene predictor for early intrahepatic recurrence of hepatocellular carcinoma after curative hepatectomy

Hideaki Somura, Norio Iizuka, Takao Tamesa, Kazuhiko Sakamoto, Takashi Hamaguchi, Ryouichi Tsunedomi, Hisafumi Yamada-Okabe, Mikiko Sawamura, Masaya Eramoto, Takanobu Miyamoto, Yoshihiko Hamamoto, Masaaki Oka
Pages: 489-495
Published online on: 01 February 2008

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Article

Analysis of the clinicopathological prognosis of stage IVb cervical carcinoma

Shin Nishio, Noriyuki Katsumata, Koji Matsumoto, Hiroshi Tanabe, Kan Yonemori, Tsutomu Kohno, Chikako Shimizu, Masashi Ando, Takahiro Kasamatsu, Yasuhiro Fujiwara
Pages: 497-503
Published online on: 01 February 2008

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Article

Immunostimulatory effect of Fms-like tyrosine kinase 3 ligand on peripheral monocyte-derived dendritic cells and natural killer cells: Utilization for ovarian cancer treatment

Noriomi Matsumura, Masaki Mandai, Junzo Hamanishi, Ken Yamaguchi, Ken Fukuhara, Haruhiko Yagi, Toshihiro Higuchi, Kenji Takakura, Shingo Fujii
Pages: 505-515
Published online on: 01 February 2008

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Article

Induction of apoptosis by pectenotoxin-2 is mediated with the induction of DR4/DR5, Egr-1 and NAG-1, activation of caspases and modulation of the Bcl-2 family in p53-deficient Hep3B hepatocellular carcinoma cells

Dong Yeok Shin, Gi Young Kim, Nam Deuk Kim, Jee Hyung Jung, Se-Kwon Kim, Ho Sung Kang, Yung Hyun Choi
Pages: 517-526
Published online on: 01 February 2008

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Article

Cytotoxicity of p-tyrosol and its derivatives may correlate with the inhibition of DNA replication initiation

Eun-Young Ahn, Yahong Jiang, Yanjun Zhang, Eun Mi Son, Song You, Shin-Won Kang, Jang-Su Park, Jee H. Jung, Burm-Jong Lee, Dong-Kyoo Kim
Pages: 527-534
Published online on: 01 February 2008

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Article

The possible roles for polyamines in the initiation process of SV40 DNA replication in vitro

Dong-Gil Kim, Juan Du, Chunhui Miao, Jee H. Jung, Sang Chul Park, Dong-Kyoo Kim
Pages: 535-539
Published online on: 01 February 2008

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Article

Prognostic role of cell apoptotic rate in prostate cancer: Outcome of a long-time follow-up study

Giuseppe Dachille, Tommaso Cai, Giuseppe Mario Ludovico, Giovanni Vestita, Giovanni Pagliarulo, Gabriella Nesi, Sandra Mazzoli, Francesca Meacci, Nicola Mondaini, Beatrice Detti, Riccardo Bartoletti
Pages: 541-545
Published online on: 01 February 2008

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Article

Antiproliferative and proapoptotic effects of rapamycin and celecoxib in malignant melanoma cell lines

Annika Bundscherer, Christian Hafner, Tim Maisch, Bernd Becker, Michael Landthaler, Thomas Vogt
Pages: 547-553
Published online on: 01 February 2008

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Article

Expression of the cell to cell adhesion molecule, ALCAM, in breast cancer patients and the potential link with skeletal metastasis

Simon R. Davies, Colin Dent, Gareth Watkins, Judy A. King, Kefah Mokbel, Wen G. Jiang
Pages: 555-561
Published online on: 01 February 2008

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Article

Corn-derived carbohydrate inositol hexaphosphate inhibits Barrett's adenocarcinoma growth by pro-apoptotic mechanisms

David W. McFadden, Dale R. Riggs, Barbara J. Jackson, Cynthia Cunningham
Pages: 563-566
Published online on: 01 February 2008

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Article

Response of normal and colon cancer epithelial cells to TNF-family apoptotic inducers

Jirina Hofmanová, Alena Vaculová, Martina Hyzd'Alová, Alois Kozubík
Pages: 567-573
Published online on: 01 February 2008

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Article

Long-term effects of short hairpin RNA-targeted human telomerase reverse transcriptase on suppression of SGC-7901 cell proliferation by inhibition of telomerase activity

Xiaobin Qian, Jing Cheng, Aiping Chen, Ying Wang, Yan Tao, Jianping Cao, Zhenqing Feng
Pages: 575-581
Published online on: 01 February 2008

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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