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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2008 Volume 19 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Varied expression and localization of multiple galectins in different cancer cell lines

Arun Satelli, Prema S. Rao, Prem K. Gupta, Paul R. Lockman, Kalkunte S. Srivenugopal, U. Subrahmanyeswara Rao
Pages: 587-594
Published online on: 01 March 2008

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Article

A ginseng saponin metabolite suppresses tumor necrosis factor-α-promoted metastasis by suppressing nuclear factor-κB signaling in murine colon cancer cells

Min-Kyung Choo, Hiroaki Sakurai, Dong-Hyun Kim, Ikuo Saiki
Pages: 595-600
Published online on: 01 March 2008

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Article

Analysis of T-helper type 1 and 2 cells and T-cytotoxic type 1 and 2 cells of sentinel lymph nodes in breast cancer

Katsuhiko Ehi, Sumiya Ishigami, Izumi Masamoto, Yoshikazu Uenosono, Shoji Natsugoe, Takaaki Arigami, Hideo Arima, Yuko Kijima, Heiji Yoshinaka, Shigehiro Yanagita, Tsutomu Kozono, Yawara Funasako, Ikuro Maruyama, Takashi Aikou
Pages: 601-607
Published online on: 01 March 2008

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Article

Expression and cellular localization of TSC-22 in normal salivary glands and salivary gland tumors: Implications for tumor cell differentiation

Yutaka Doi, Hitoshi Kawamata, Yuko Ono, Takahiro Fujimori, Yutaka Imai
Pages: 609-616
Published online on: 01 March 2008

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Article

Breast carcinomas expressing basal markers have poor clinical outcome regardless of estrogen receptor status

Bong Kyung Shin, Youngseok Lee, Jung Bok Lee, Han Kyeom Kim, Jae Bok Lee, Su Jin Cho, Aeree Kim
Pages: 617-625
Published online on: 01 March 2008

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Article

Overexpression of connexin 26 in carcinoma of the pancreas

Naganori Kyo, Hirofumi Yamamoto, Yutaka Takeda, Koji Ezumi, Chew Yee Ngan, Motokazu Terayama, Masakazu Miyake, Ichiro Takemasa, Masataka Ikeda, Yuichiro Doki, Keizo Dono, Mitsugu Sekimoto, Hiroshi Nojima, Morito Monden
Pages: 627-631
Published online on: 01 March 2008

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Article

Up-regulation of the BTG2 gene in TPA- or RA-treated HL-60 cell lines

Byoung-Ok Cho, Yong-Wook Jeong, Seoung-Hoon Kim, Kun Park, Ji-Hye Lee, Gi Ryang Kweon, Jong-Chun Park
Pages: 633-637
Published online on: 01 March 2008

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Article

The progression of gliomas is associated with cancer stem cell phenotype

Doo-Sik Kong, Mi Hyun Kim, Woong-Yang Park, Yeon-Lim Suh, Jung-Il Lee, Kwan Park, Jong Hyun Kim, Do-Hyun Nam
Pages: 639-643
Published online on: 01 March 2008

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Article

Clinicopathological significance of cyclooxygenase-2 expression in hypopharyngeal squamous cell carcinoma

Rieko Goto, Hiroshi Hoshikawa, Takashi Fujii, Kanako Indo, Kunitoshi Yoshino, Katsumi Imaida, Nozomu Mori
Pages: 645-650
Published online on: 01 March 2008

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Article

Prognostic utility of fluorescence in situ hybridization for determining HER2 gene amplification in breast cancer

Makoto Kammori, Rie Kurabayashi, Mitsuhiko Kashio, Akiko Sakamoto, Masataka Yoshimoto, Sadao Amano, Michio Kaminishi, Tetsu Yamada, Kaiyo Takubo
Pages: 651-656
Published online on: 01 March 2008

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Article

Heparanase and vascular endothelial growth factor expression in the progression of oral mucosal melanoma

Rosario S. Rivera, Hitoshi Nagatsuka, Chong Huat Siar, Mehmet Gunduz, Hidetsugu Tsujigiwa, Phuu Pwint Han, Naoki Katase, Ryo Tamamura, Kok Han Ng, Yoshio Naomoto, Motowo Nakajima, Noriyuki Nagai
Pages: 657-661
Published online on: 01 March 2008

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Article

Promoter hypomethylation of the N-acetyltransferase 1 gene in breast cancer

Sun Jung Kim, Han-Sung Kang, Hye Lim Chang, Yoon Chul Jung, Hyung-Bo Sim, Keun Seok Lee, Jungsil Ro, Eun Sook Lee
Pages: 663-668
Published online on: 01 March 2008

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Article

Inhibition of DLC-1 gene expression by RNA interference in the colon cancer LoVo cell line

Yueling Jin, Xiaoqiang Tian, Yanfang Shang, Peiling Huang
Pages: 669-674
Published online on: 01 March 2008

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Article

Novel biomarker candidates for gastric cancer

Sanghwa Yang, Hyun Cheol Chung
Pages: 675-680
Published online on: 01 March 2008

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Article

Hedgehog signalling in medulloblastoma, glioblastoma and neuroblastoma

Mehdi H. Shahi, Aiala Lorente, Javier S. Castresana
Pages: 681-688
Published online on: 01 March 2008

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Article

BAG-1 inhibits PPARγ-induced cell death, but not PPARγ-induced transcription, cell cycle arrest or differentiation in breast cancer cells

Simon J. Crabb, Angela Hague, Peter W.M. Johnson, Graham Packham
Pages: 689-696
Published online on: 01 March 2008

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Article

PDGFRα/β expression correlates with the metastatic behavior of human colorectal cancer: A possible rationale for a molecular targeting strategy

Thomas C. Wehler, Kirsten Frerichs, Claudine Graf, Daniel Drescher, Katrin Schimanski, Stefan Biesterfeld, Martin R. Berger, Stephan Kanzler, Theodor Junginger, Peter R. Galle, Markus Moehler, Ines Gockel, Carl C. Schimanski
Pages: 697-704
Published online on: 01 March 2008

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Article

Malignant transformation of mature cystic teratoma of the ovary including three cases occurring during follow-up period

Ken Yamaguchi, Masaki Mandai, Ken Fukuhara, Toshihiro Higuchi, Junzo Hamanishi, Kenji Takakura, Shingo Fujii
Pages: 705-711
Published online on: 01 March 2008

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Article

Decreased expression of RUNX3 is correlated with tumor progression and poor prognosis in patients with esophageal squamous cell carcinoma

Hironori Sugiura, Hideyuki Ishiguro, Yoshiyuki Kuwabara, Masahiro Kimura, Akira Mitsui, Yoichiro Mori, Ryo Ogawa, Takeyasu Katada, Koshiro Harata, Yoshitaka Fujii
Pages: 713-719
Published online on: 01 March 2008

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Article

Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression

Youichirou Matsuzaki, Makoto Koyama, Toshiaki Hitomi, Tomoya Yokota, Mayumi Kawanaka, Akiyoshi Nishikawa, Doris Germain, Toshiyuki Sakai
Pages: 721-727
Published online on: 01 March 2008

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Article

Prognostic value of 5-fluorouracil metabolic enzyme genes in Dukes' stage B and C colorectal cancer patients treated with oral 5-fluorouracil-based adjuvant chemotherapy

Hideki Yamada, Hisae Iinuma, Toshiaki Watanabe
Pages: 729-735
Published online on: 01 March 2008

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Article

AP-1 transcription factor decoy reduces the TGF-β1-induced cell growth in scleroderma fibroblasts through inhibition of cyclin E

Jae-We Cho, Young-Chang Cha, Kyu-Suk Lee
Pages: 737-741
Published online on: 01 March 2008

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Article

Cell surface N-glycosylation and sialylation regulate galectin-3-induced apoptosis in human diffuse large B cell lymphoma

Osamu Suzuki, Masafumi Abe
Pages: 743-748
Published online on: 01 March 2008

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Article

K252a is highly effective in suppressing the growth of human endometrial cancer cells, but has little effect on normal human endometrial epithelial cells

Noriyuki Takai, Tami Ueda, Masakazu Nishida, Kaei Nasu, Hisashi Narahara
Pages: 749-753
Published online on: 01 March 2008

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Case Report

Alteration of the chemoresistant gene expression during chemotherapy for colon cancer: A molecular case report

Yuji Toiyama, Yasuhiro Inoue, Junichiro Hiro, Eiki Ojima, Hideki Watanabe, Chikao Miki, Masato Kusunoki
Pages: 755-759
Published online on: 01 March 2008

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Article

Neoadjuvant therapy of gastric cancer with the human monoclonal IgM antibody SC-1: Impact on the immune system

Ulrich Beutner, Udo Lorenz, Bertram Illert, Loretta Rott, Wolfgang Timmermann, H. Peter Vollmers, Hans Konrad Müller-Hermelink, Arnulf Thiede, Karin Ulrichs
Pages: 761-769
Published online on: 01 March 2008

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Article

Prognostic impact of p53 Pro72 homozygous genotype in non-small cell lung cancer patients

Laura Boldrini, Silvia Gisfredi, Silvia Ursino, Marco Lucchi, Giordana Greco, Alfredo Mussi, Gabriella Fontanini
Pages: 771-773
Published online on: 01 March 2008

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Article

Genetic classification of ovarian carcinoma based on microsatellite analysis: Relationship to clinicopathological features and patient survival

Zhang Huan, Kentaro Nakayama, Naomi Nakayama, Masako Ishibashi, Shamima Yeasmin, Atsuko Katagiri, Indri Nuryani Purwana, Kouji Iida, Riruke Maruyama, Manabu Fukumoto, Kohji Miyazaki
Pages: 775-781
Published online on: 01 March 2008

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Article

Disease family history and modification of breast cancer risk in common BRCA2 variants

Ian Jonathan Seymour, Silvia Casadei, Valentina Zampiga, Simonetta Rosato, Rita Danesi, Fabio Falcini, Miria Strada, Nori Morini, Carlo Naldoni, Angelo Paradiso, Stefania Tommasi, Francesco Schittulli, Dino Amadori, Daniele Calistri
Pages: 783-786
Published online on: 01 March 2008

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Article

Adiponectin effects on human breast cancer cells are dependent on 17-β estradiol

Georg H. Pfeiler, Christa Buechler, Markus Neumeier, Andreas Schäffler, Gerd Schmitz, Olaf Ortmann, Oliver Treeck
Pages: 787-793
Published online on: 01 March 2008

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Article

Overexpression of humbug promotes malignant progression in human gastric cancer cells

Jeong-Hyung Lee
Pages: 795-800
Published online on: 01 March 2008

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Article

Stilbene analogues affect cell cycle progression and apoptosis independently of each other in an MCF-7 array of clones with distinct genetic and chemoresistant backgrounds

Yvonne Bader, Sibylle Madlener, Stephan Strasser, Susanne Maier, Philipp Saiko, Nicole Stark, Ruxandra Popescu, Daniela Huber, Michaela Gollinger, Thomas Erker, Norbert Handler, Akos Szakmary, Walter Jäger, Brigitte Kopp, Ioannis Tentes, Monika Fritzer-Szekeres, Georg Krupitza, Thomas Szekeres
Pages: 801-810
Published online on: 01 March 2008

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Article

Detection of an elevated HER2 expression in MCF-7 breast cancer cells overexpressing estrogen receptor β1

Claus Lattrich, Ingolf Juhasz-Boess, Olaf Ortmann, Oliver Treeck
Pages: 811-817
Published online on: 01 March 2008

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Article

Rhabdoid tumors in children: Prognostic factors in 70 patients diagnosed in Germany

Harald Reinhard, Jennifer Reinert, Rita Beier, Rhoikos Furtwängler, Muhanat Alkasser, Stefan Rutkowski, Michael Frühwald, Ewa Koscielniak, Ivo Leuschner, Peter Kaatsch, Norbert Graf
Pages: 819-823
Published online on: 01 March 2008

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Article

Disruption of the MYC transcriptional function by a small-molecule antagonist of MYC/MAX dimerization

Xiaohong Lu, Peter K. Vogt, Dale L. Boger, John Lunec
Pages: 825-830
Published online on: 01 March 2008

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Article

Phase I trial of PC-Spes2 in advanced hormone refractory prostate cancer

Majid Shabbir, Julie Love, Bruce Montgomery
Pages: 831-835
Published online on: 01 March 2008

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

KDM5D expression is lost in cisplatin‑resistant neuroblastoma cells

Natalia Podhorska, Jan Hrabeta, Marie Belhajova, Tomas Eckschlager
Article Number: 79
Published online on: 25 February 2026

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Article Open Access

Role of iron and TfR1 in the application of high‑dose ascorbate against pancreatic cancer

Alban Piotrowsky, Christian Leischner, Hendrik Schmieder, Katja Detert, Kathrin Schneider, Johanna Schulte, Sabrina Hammerschmidt, Luigi Marongiu, Olga Renner, Markus Burkard, Sascha Venturelli
Article Number: 78
Published online on: 24 February 2026

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Review Open Access

Advances in immunotherapy and targeted therapy for nasopharyngeal carcinoma: Current progress and combined approaches (Review)

Zhen Yang, Huajun Liu, Meilin Chen, Liming Zhang, Meiling Gong, Ruilian Yu
Article Number: 77
Published online on: 24 February 2026

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Retraction Open Access

[Retracted] Overexpression of SHP2 tyrosine phosphatase promotes the tumorigenesis of breast carcinoma

Zhongqian Hu, Haoshu Fang, Xinyi Wang, Danlei Chen, Zhuo Chen, Siying Wang
Article Number: 76
Published online on: 24 February 2026

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Article Open Access

NR4A1 mediates chemotherapy‑induced senescence via the PI3K/AKT pathway in gastric cancer cells

Tingyu Zhang, Yue Wang, Jiuna Zhang, Xueshuai Ye, Yanfeng Shen, Zhiwei Zhang
Article Number: 75
Published online on: 18 February 2026

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Article

Hypoxia‑induced miR‑135b‑5p promotes neuroendocrine differentiation of prostate cancer cells through HIF1AN‑HIF1α axis

Pampana Sandhya Venkata Lakshmi, Jagrati Parashar, Biswajit Biswas, Ramesh Ummanni
Article Number: 74
Published online on: 16 February 2026

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Retraction Open Access

[Retracted] Knockdown of human antigen R reduces the growth and invasion of breast cancer cells in vitro and affects expression of cyclin D1 and MMP‑9

Zhu Yuan, Andrew J. Sanders, Lin Ye, Yu Wang, Wen G. Jiang
Article Number: 73
Published online on: 16 February 2026

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Review Open Access

Liquid biopsy in malignant primary bone tumors: Clinical applications of circulating tumor DNA and circulating tumor cells for diagnosis, prognosis and treatment monitoring (Review)

Bin Tian, Xuesong Chen, Jiang Zheng, Xin Kang
Article Number: 72
Published online on: 12 February 2026

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Article Open Access

Tumor visualization and evaluation of glioblastoma in mice using small animal 9.4T MRI and PET‑CT with high resolution

Shuangyi Li, Wenjiao Gu, Ying Jiang, Ting Liu, Limei Shuai, Yujie Wei, Youming Shi, Havyarimana Juvenal, Zhimin Wang, Yucai Wei, Bofan Wu, Xiaochun Zhou, Yumin Li, Futian Tang
Article Number: 71
Published online on: 12 February 2026

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Expression of Concern Open Access

[Expression of Concern] Interference of STAT 5b expression enhances the chemo‑sensitivity of gastric cancer cells to gefitinib by promoting mitochondrial pathway‑mediated cell apoptosis

Tao Sun, Yanfei Jia, Dongjie Xiao
Article Number: 70
Published online on: 11 February 2026

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Article Open Access

Regorafenib and Nifuroxazide exert enhanced suppression of hepatocellular carcinoma by inhibiting STAT3 and immune remodeling

Kun Li, Jinwei Chen, Zhi Zheng, Yichun Gao, Jiayu Zhang, Wenya Ding, Tongguo Yang, Yuyang Gu, Xuhua Duan, Tiesuo Zhao, Huijie Jia, Pengfei Chen, Jianzhuang Ren
Article Number: 69
Published online on: 11 February 2026

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Article Open Access

Suppressive role of SCN4B in the epithelial‑mesenchymal transition of lung adenocarcinoma

Mengnan Guo, He Li, Zhifang Zhao, Yuanyuan Wang, Jiaqi Tang, Binghan Zhong, Yunxia Zhao
Article Number: 68
Published online on: 10 February 2026

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Retraction Open Access

[Retracted] miR‑218 suppresses cardiac myxoma proliferation by targeting myocyte enhancer factor 2D

Quanxing Cao, Pingshuan Dong, Yanyu Wang, Junwei Zhang, Xinge Shi, Yongsheng Wang
Article Number: 67
Published online on: 09 February 2026

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Review

Impact of the intratumoral resident microbiome on the immune microenvironment of malignant tumors (Review)

Han Na Oh, Hoon Hur
Article Number: 66
Published online on: 06 February 2026

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Correction Open Access

[Corrigendum] Hypoxia and macrophages promote glioblastoma invasion by the CCL4‑CCR5 axis

Ying Wang, Tao Liu, Ning Yang, Shuo Xu, Xingang Li, Donghai Wang
Article Number: 65
Published online on: 04 February 2026

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Review Open Access

Origin dictates function: The dual roles of exosomes derived from diverse origins in the onset and progression of colorectal cancer (Review)

Zhao Guo, Haoyan Zhuang, Qingfeng Liu
Article Number: 64
Published online on: 03 February 2026

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Article Open Access

Quercetin reduces expression of ATP‑binding cassette transporters by regulating the PTEN/PI3K/AKT signaling pathway in breast cancer cells

Wentao Fu, Leying Lin, Jie Li, Fei Qin, Chuan Chen, Yinglian Cai, Yilun Cai, Yiling Huang, Wang Yang, Shanshan Zhu
Article Number: 63
Published online on: 02 February 2026

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Article Open Access

POSTN+ fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling

Chenyang Zhang, Si Chen, Chenghui Qian, Wanqi Lv, Qian Zhang, Yanjin Wang, Yuqiong Wu, Xue Liu
Article Number: 62
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] EGFR/HER2 inhibitors effectively reduce the malignant potential of MDR breast cancer evoked by P‑gp substrates in vitro and in vivo

Yiting Jin, Wei Zhang, Hongying Wang, Zijing Zhang, Chengyu Chu, Xiuping Liu, Qiang Zou
Article Number: 61
Published online on: 02 February 2026

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Article

Tumor‑associated glucocorticoid inhibition by mifepristone reduces polymorphonuclear myeloid‑derived suppressor cells and promotes antitumor immunity in triple‑negative breast cancer‑bearing mice

Masato Kobayashi, Chisana Konno, Ayato Shimizu, Masanori Kobayashi, Tatsuya Hori
Article Number: 60
Published online on: 30 January 2026

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Review Open Access

Mitochondria in T‑cell tumor immunity and tumor therapies targeting mitochondria (Review)

Minjie Zhou, Yijie Xie, Zhipeng Liu, Yi He, Yibing Yin, Keyu Chen, Zhengyu Zhao, Chengshun Zhang, Dingjun Cai
Article Number: 59
Published online on: 29 January 2026

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Article Open Access

TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Review Open Access

Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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Article Open Access

High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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May-2026 Volume 55 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

ZBTB7A promotes malignant phenotypes in ovarian cancer through transcriptional activation of CRLF1

Xiaobai Hao, Yu Chen
Article Number: 102
Published online on: 24 March 2026

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Article Open Access

MS4322 is a selective protein arginine methyltransferase 5 degrader with antitumor effects in cervical cancer cells

Rui Luo, Jingping Chen, Zhaojie Chen, Surong Wang, Tianfeng Liu, Yang Xu
Article Number: 101
Published online on: 24 March 2026

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Retraction Open Access

[Retracted] Roles of the SNHG7/microRNA‑9‑5p/DPP4 ceRNA network in the growth and 131I resistance of thyroid carcinoma cells through PI3K/Akt activation

Wanzhi Chen, Jichun Yu, Rong Xie, Tao Zhou, Chengfeng Xiong, Shuyong Zhang, Meijun Zhong
Article Number: 100
Published online on: 23 March 2026

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Article Open Access

Andrographis exerts antitumor effects and enhances 5‑FU efficacy via the alteration of ferroptosis‑related genes in esophageal squamous cell carcinoma

Kosuke Yoshimura, Tadanobu Shimura, Ruiya Ma, Yaxuan Huang, Takahito Kitajima, Shinji Yamashita, Yuki Sato, Koki Higashi, Mikio Kawamura, Hiromi Yasuda, Yuhki Koike, Yoshiki Okita, Shigeyuki Yoshiyama, Minako Kobayashi, Masaki Ohi, Hiroki Ohge, Shinya Takahashi, Ajay Goel, Yoshinaga Okugawa, Yuji Toiyama
Article Number: 99
Published online on: 20 March 2026

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Article Open Access

Sphingosine‑1‑phosphate receptor 1 enhances olfactory receptor 51E1‑mediated inhibition of proliferation via Src/JNK signaling in prostate cancer cells

Kiheon Kim, Jinwoo Lee, Chulwon Choi, Jungnam Bae, Hee-Jung Choi, Won-Ki Huh
Article Number: 98
Published online on: 19 March 2026

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Review Open Access

Mechanistic insights into the roles of astragalosides and Astragalus polysaccharides in gynecological and breast cancers (Review)

Ruixin Liu, Zhanyu Lin, Yuelin Li, Yuetong Ci, Zhengqi Guo, Zhenguo Xu
Article Number: 97
Published online on: 19 March 2026

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Retraction Open Access

[Retracted] Inhibition of tankyrase 1 in human gastric cancer cells enhances telomere shortening by telomerase inhibitors 

Hao Zhang, Meng-Hua Yang, Jing-Jing Zhao, Ling Chen, Song-Tao Yu, Xu-Dong Tang, Dian-Chun Fang, Shi-Ming Yang
Article Number: 96
Published online on: 16 March 2026

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Article Open Access

Silencing of SIVA‑1 promotes cisplatin resistance in gastric cancer via the Bcl‑2/BAX‑mediated mitochondria‑dependent apoptosis pathway

Zheng-Yi Shi, Zheng-Rong Ding, Yu-Liang Huang, Yuan-Rui Lei, Hai-Bin Huang, Yan Qing, Miao-Ren Deng, Xu-Man Lu, Xu-Dong Dong, Long-Jie Xia, Sheng Xu, Xiao-Gang Zhong, Lei Li, Fan-Biao Kong, Xiao-Tong Wang
Article Number: 95
Published online on: 13 March 2026

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Article Open Access

Depleting HIF‑1α attenuates the progression of osteosarcoma, but tumorigenicity is sustained through HIF‑independent pathways

Ayaka Kunishima, Takatsune Shimizu, Tetsuya Takimoto, Atsunobu Sagara, Hiroyuki Nobusue, Hidetoshi Hasuwa, Shinya Hasegawa, Yuka Tamaoki, Hitomi Miyake, Yumi Fukuchi, Hideyuki Saya, Akihiro Muto
Article Number: 94
Published online on: 12 March 2026

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Article Open Access

Unveiling the role of ANGPT2 in esophageal cancer: A prognostic factor and potential oncogene

Zhigang Zhai, Zhenyu Xue, Yuan Fang, Yixu Fan, Shijiao Li, Yunpeng Yu, Chuansheng Chen, Kaijun Zhang, Deyu Chen, Xiang Tang, Rui Ling
Article Number: 93
Published online on: 12 March 2026

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Article Open Access

POLQ promotes tumor progression and immunosuppression via ATM‑P53 signaling in endometrial cancer

Ningning Zhu, Juanjuan Wang, Xiaoli Zhang, Kai Tang, Lei Gong, Yi Hu
Article Number: 92
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate and sodium citrate target glycolysis, suppress survivin, and induce mitochondrial‑mediated apoptosis in gastric cancer cells and inhibit gastric orthotopic transplantation tumor growth

Ting-An Wang, Xiao-Dong Zhang, Xing-Yu Guo, Shu-Lin Xian, Yun-Fei Lu
Article Number: 91
Published online on: 11 March 2026

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Review Open Access

Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review)

Zidong Xia, Huishan Zhai, Lei Zheng, Cheng Wang
Article Number: 90
Published online on: 09 March 2026

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Retraction Open Access

[Retracted] Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine‑γ‑lyase function

Liangyu Chen, Xinxing Li, Libo Liu, Bo Yu, Yixue Xue, Yunhui Liu
Article Number: 89
Published online on: 09 March 2026

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Review Open Access

Advances in the application of frailty scoring in the diagnosis and management of elderly patients with multiple myeloma (Review)

Junlun Liu, Danyu Li, Chao Li, Zhuoren Chen
Article Number: 88
Published online on: 06 March 2026

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Expression of Concern Open Access

[Expression of Concern] c‑Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma 

Lei You, Xiaoxia Ren, Yongxing Du, Wenjing Zhao, Ming Cui, Ge Chen, Yupei Zhao
Article Number: 87
Published online on: 05 March 2026

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Review Open Access

CXCL1 in triple‑negative breast cancer: Mechanisms, challenges, and therapeutic opportunities (Review)

Hiba Al Sayegh, Zahraa Assi, Amjad Kanaan, Mirvat El Sibai
Article Number: 86
Published online on: 03 March 2026

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Article Open Access

Cellular and inflammatory characteristics of patient‑derived glioblastoma organoids during in vitro cultivation

Jessica Nojszewski, Nils Oliver Schröder, Jacqueline Clüver, Jonna Holler, Hajrullah Ahmeti, Michael Synowitz, Janka Held-Feindt
Article Number: 85
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Growth and differentiation factor‑9 promotes adhesive and motile capacity of prostate cancer cells by up‑regulating FAK and Paxillin via Smad dependent pathway 

Sivan M. Bokobza, Lin Ye, Howard G. Kynaston, Wen G. Jiang
Article Number: 84
Published online on: 02 March 2026

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Article Open Access

Platycodin D sensitizes head and neck squamous cell carcinoma to cisplatin by inducing autophagy arrest

Minji Bae, Min Kyeong Lee, Mi Gyeong Jeong, Yeonseo Lee, Harim Joo, Young Chan Lee, Jung Woo Lee, Su Il Kim, Seong-Gyu Ko, Young-Gyu Eun
Article Number: 83
Published online on: 27 February 2026

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Article Open Access

ACSBG1‑driven lipid reprogramming unveiled: A fatty acid metabolism‑associated prognostic model for lung adenocarcinoma

Panxin Hu, Anan Li
Article Number: 82
Published online on: 27 February 2026

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Article Open Access

Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation

Chao Li, Lei Yang, Yudong Zhang, Baocheng Zhao, Hao Qu
Article Number: 81
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways

Hongxia Zhang, Ruifeng Dong, Ping Zhang, Yankui Wang
Article Number: 80
Published online on: 25 February 2026

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