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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2008 Volume 19 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Varied expression and localization of multiple galectins in different cancer cell lines

Arun Satelli, Prema S. Rao, Prem K. Gupta, Paul R. Lockman, Kalkunte S. Srivenugopal, U. Subrahmanyeswara Rao
Pages: 587-594
Published online on: 01 March 2008

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Article

A ginseng saponin metabolite suppresses tumor necrosis factor-α-promoted metastasis by suppressing nuclear factor-κB signaling in murine colon cancer cells

Min-Kyung Choo, Hiroaki Sakurai, Dong-Hyun Kim, Ikuo Saiki
Pages: 595-600
Published online on: 01 March 2008

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Article

Analysis of T-helper type 1 and 2 cells and T-cytotoxic type 1 and 2 cells of sentinel lymph nodes in breast cancer

Katsuhiko Ehi, Sumiya Ishigami, Izumi Masamoto, Yoshikazu Uenosono, Shoji Natsugoe, Takaaki Arigami, Hideo Arima, Yuko Kijima, Heiji Yoshinaka, Shigehiro Yanagita, Tsutomu Kozono, Yawara Funasako, Ikuro Maruyama, Takashi Aikou
Pages: 601-607
Published online on: 01 March 2008

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Article

Expression and cellular localization of TSC-22 in normal salivary glands and salivary gland tumors: Implications for tumor cell differentiation

Yutaka Doi, Hitoshi Kawamata, Yuko Ono, Takahiro Fujimori, Yutaka Imai
Pages: 609-616
Published online on: 01 March 2008

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Article

Breast carcinomas expressing basal markers have poor clinical outcome regardless of estrogen receptor status

Bong Kyung Shin, Youngseok Lee, Jung Bok Lee, Han Kyeom Kim, Jae Bok Lee, Su Jin Cho, Aeree Kim
Pages: 617-625
Published online on: 01 March 2008

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Article

Overexpression of connexin 26 in carcinoma of the pancreas

Naganori Kyo, Hirofumi Yamamoto, Yutaka Takeda, Koji Ezumi, Chew Yee Ngan, Motokazu Terayama, Masakazu Miyake, Ichiro Takemasa, Masataka Ikeda, Yuichiro Doki, Keizo Dono, Mitsugu Sekimoto, Hiroshi Nojima, Morito Monden
Pages: 627-631
Published online on: 01 March 2008

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Article

Up-regulation of the BTG2 gene in TPA- or RA-treated HL-60 cell lines

Byoung-Ok Cho, Yong-Wook Jeong, Seoung-Hoon Kim, Kun Park, Ji-Hye Lee, Gi Ryang Kweon, Jong-Chun Park
Pages: 633-637
Published online on: 01 March 2008

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Article

The progression of gliomas is associated with cancer stem cell phenotype

Doo-Sik Kong, Mi Hyun Kim, Woong-Yang Park, Yeon-Lim Suh, Jung-Il Lee, Kwan Park, Jong Hyun Kim, Do-Hyun Nam
Pages: 639-643
Published online on: 01 March 2008

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Article

Clinicopathological significance of cyclooxygenase-2 expression in hypopharyngeal squamous cell carcinoma

Rieko Goto, Hiroshi Hoshikawa, Takashi Fujii, Kanako Indo, Kunitoshi Yoshino, Katsumi Imaida, Nozomu Mori
Pages: 645-650
Published online on: 01 March 2008

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Article

Prognostic utility of fluorescence in situ hybridization for determining HER2 gene amplification in breast cancer

Makoto Kammori, Rie Kurabayashi, Mitsuhiko Kashio, Akiko Sakamoto, Masataka Yoshimoto, Sadao Amano, Michio Kaminishi, Tetsu Yamada, Kaiyo Takubo
Pages: 651-656
Published online on: 01 March 2008

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Article

Heparanase and vascular endothelial growth factor expression in the progression of oral mucosal melanoma

Rosario S. Rivera, Hitoshi Nagatsuka, Chong Huat Siar, Mehmet Gunduz, Hidetsugu Tsujigiwa, Phuu Pwint Han, Naoki Katase, Ryo Tamamura, Kok Han Ng, Yoshio Naomoto, Motowo Nakajima, Noriyuki Nagai
Pages: 657-661
Published online on: 01 March 2008

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Article

Promoter hypomethylation of the N-acetyltransferase 1 gene in breast cancer

Sun Jung Kim, Han-Sung Kang, Hye Lim Chang, Yoon Chul Jung, Hyung-Bo Sim, Keun Seok Lee, Jungsil Ro, Eun Sook Lee
Pages: 663-668
Published online on: 01 March 2008

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Article

Inhibition of DLC-1 gene expression by RNA interference in the colon cancer LoVo cell line

Yueling Jin, Xiaoqiang Tian, Yanfang Shang, Peiling Huang
Pages: 669-674
Published online on: 01 March 2008

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Article

Novel biomarker candidates for gastric cancer

Sanghwa Yang, Hyun Cheol Chung
Pages: 675-680
Published online on: 01 March 2008

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Article

Hedgehog signalling in medulloblastoma, glioblastoma and neuroblastoma

Mehdi H. Shahi, Aiala Lorente, Javier S. Castresana
Pages: 681-688
Published online on: 01 March 2008

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Article

BAG-1 inhibits PPARγ-induced cell death, but not PPARγ-induced transcription, cell cycle arrest or differentiation in breast cancer cells

Simon J. Crabb, Angela Hague, Peter W.M. Johnson, Graham Packham
Pages: 689-696
Published online on: 01 March 2008

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Article

PDGFRα/β expression correlates with the metastatic behavior of human colorectal cancer: A possible rationale for a molecular targeting strategy

Thomas C. Wehler, Kirsten Frerichs, Claudine Graf, Daniel Drescher, Katrin Schimanski, Stefan Biesterfeld, Martin R. Berger, Stephan Kanzler, Theodor Junginger, Peter R. Galle, Markus Moehler, Ines Gockel, Carl C. Schimanski
Pages: 697-704
Published online on: 01 March 2008

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Article

Malignant transformation of mature cystic teratoma of the ovary including three cases occurring during follow-up period

Ken Yamaguchi, Masaki Mandai, Ken Fukuhara, Toshihiro Higuchi, Junzo Hamanishi, Kenji Takakura, Shingo Fujii
Pages: 705-711
Published online on: 01 March 2008

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Article

Decreased expression of RUNX3 is correlated with tumor progression and poor prognosis in patients with esophageal squamous cell carcinoma

Hironori Sugiura, Hideyuki Ishiguro, Yoshiyuki Kuwabara, Masahiro Kimura, Akira Mitsui, Yoichiro Mori, Ryo Ogawa, Takeyasu Katada, Koshiro Harata, Yoshitaka Fujii
Pages: 713-719
Published online on: 01 March 2008

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Article

Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression

Youichirou Matsuzaki, Makoto Koyama, Toshiaki Hitomi, Tomoya Yokota, Mayumi Kawanaka, Akiyoshi Nishikawa, Doris Germain, Toshiyuki Sakai
Pages: 721-727
Published online on: 01 March 2008

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Article

Prognostic value of 5-fluorouracil metabolic enzyme genes in Dukes' stage B and C colorectal cancer patients treated with oral 5-fluorouracil-based adjuvant chemotherapy

Hideki Yamada, Hisae Iinuma, Toshiaki Watanabe
Pages: 729-735
Published online on: 01 March 2008

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Article

AP-1 transcription factor decoy reduces the TGF-β1-induced cell growth in scleroderma fibroblasts through inhibition of cyclin E

Jae-We Cho, Young-Chang Cha, Kyu-Suk Lee
Pages: 737-741
Published online on: 01 March 2008

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Article

Cell surface N-glycosylation and sialylation regulate galectin-3-induced apoptosis in human diffuse large B cell lymphoma

Osamu Suzuki, Masafumi Abe
Pages: 743-748
Published online on: 01 March 2008

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Article

K252a is highly effective in suppressing the growth of human endometrial cancer cells, but has little effect on normal human endometrial epithelial cells

Noriyuki Takai, Tami Ueda, Masakazu Nishida, Kaei Nasu, Hisashi Narahara
Pages: 749-753
Published online on: 01 March 2008

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Case Report

Alteration of the chemoresistant gene expression during chemotherapy for colon cancer: A molecular case report

Yuji Toiyama, Yasuhiro Inoue, Junichiro Hiro, Eiki Ojima, Hideki Watanabe, Chikao Miki, Masato Kusunoki
Pages: 755-759
Published online on: 01 March 2008

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Article

Neoadjuvant therapy of gastric cancer with the human monoclonal IgM antibody SC-1: Impact on the immune system

Ulrich Beutner, Udo Lorenz, Bertram Illert, Loretta Rott, Wolfgang Timmermann, H. Peter Vollmers, Hans Konrad Müller-Hermelink, Arnulf Thiede, Karin Ulrichs
Pages: 761-769
Published online on: 01 March 2008

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Article

Prognostic impact of p53 Pro72 homozygous genotype in non-small cell lung cancer patients

Laura Boldrini, Silvia Gisfredi, Silvia Ursino, Marco Lucchi, Giordana Greco, Alfredo Mussi, Gabriella Fontanini
Pages: 771-773
Published online on: 01 March 2008

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Article

Genetic classification of ovarian carcinoma based on microsatellite analysis: Relationship to clinicopathological features and patient survival

Zhang Huan, Kentaro Nakayama, Naomi Nakayama, Masako Ishibashi, Shamima Yeasmin, Atsuko Katagiri, Indri Nuryani Purwana, Kouji Iida, Riruke Maruyama, Manabu Fukumoto, Kohji Miyazaki
Pages: 775-781
Published online on: 01 March 2008

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Article

Disease family history and modification of breast cancer risk in common BRCA2 variants

Ian Jonathan Seymour, Silvia Casadei, Valentina Zampiga, Simonetta Rosato, Rita Danesi, Fabio Falcini, Miria Strada, Nori Morini, Carlo Naldoni, Angelo Paradiso, Stefania Tommasi, Francesco Schittulli, Dino Amadori, Daniele Calistri
Pages: 783-786
Published online on: 01 March 2008

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Article

Adiponectin effects on human breast cancer cells are dependent on 17-β estradiol

Georg H. Pfeiler, Christa Buechler, Markus Neumeier, Andreas Schäffler, Gerd Schmitz, Olaf Ortmann, Oliver Treeck
Pages: 787-793
Published online on: 01 March 2008

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Article

Overexpression of humbug promotes malignant progression in human gastric cancer cells

Jeong-Hyung Lee
Pages: 795-800
Published online on: 01 March 2008

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Article

Stilbene analogues affect cell cycle progression and apoptosis independently of each other in an MCF-7 array of clones with distinct genetic and chemoresistant backgrounds

Yvonne Bader, Sibylle Madlener, Stephan Strasser, Susanne Maier, Philipp Saiko, Nicole Stark, Ruxandra Popescu, Daniela Huber, Michaela Gollinger, Thomas Erker, Norbert Handler, Akos Szakmary, Walter Jäger, Brigitte Kopp, Ioannis Tentes, Monika Fritzer-Szekeres, Georg Krupitza, Thomas Szekeres
Pages: 801-810
Published online on: 01 March 2008

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Article

Detection of an elevated HER2 expression in MCF-7 breast cancer cells overexpressing estrogen receptor β1

Claus Lattrich, Ingolf Juhasz-Boess, Olaf Ortmann, Oliver Treeck
Pages: 811-817
Published online on: 01 March 2008

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Article

Rhabdoid tumors in children: Prognostic factors in 70 patients diagnosed in Germany

Harald Reinhard, Jennifer Reinert, Rita Beier, Rhoikos Furtwängler, Muhanat Alkasser, Stefan Rutkowski, Michael Frühwald, Ewa Koscielniak, Ivo Leuschner, Peter Kaatsch, Norbert Graf
Pages: 819-823
Published online on: 01 March 2008

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Article

Disruption of the MYC transcriptional function by a small-molecule antagonist of MYC/MAX dimerization

Xiaohong Lu, Peter K. Vogt, Dale L. Boger, John Lunec
Pages: 825-830
Published online on: 01 March 2008

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Article

Phase I trial of PC-Spes2 in advanced hormone refractory prostate cancer

Majid Shabbir, Julie Love, Bruce Montgomery
Pages: 831-835
Published online on: 01 March 2008

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Journal Cover
June-2026 Volume 55 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

E3 ubiquitin ligase RNF40: Structure, function and its context‑dependent roles in tumorigenesis (Review)

Zikun Wu, Hang Yang, Guanglong Chen, Weijie Zhao, Banghe Bao, Chai Luv, Wenpu Zhu, Faqiang Liu, Huihan Ai, Zhi Li
Article Number: 121
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 120
Published online on: 27 April 2026

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Article Open Access

Hypermethylation‑induced silencing of ITGA4 promotes oral squamous cell carcinoma progression through SNX5 upregulation

Nguyen Ngoc Thuy Tien, Han-Cheol Choe, Sang-Gun Ahn
Article Number: 119
Published online on: 24 April 2026

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Expression of Concern Open Access

[Expression of Concern] Pifithrin‑μ is efficacious against non‑small cell lung cancer via inhibition of heat shock protein 70

Yang Zhou, Jingping Ma, Jiahong Zhang, Li He, Jianhua Gong, Cong Long
Article Number: 118
Published online on: 22 April 2026

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Article Open Access

Inhibitory role of angiopoietin‑like 4 for cancer progression in oropharyngeal squamous cell carcinoma

Takuya Mikoshiba, Mariko Sekimizu, Nana Nakahara, Shin Saito, Keisuke Yoshihama, Ryoto Nagai, Takeyuki Kono, Hiroyuki Ozawa
Article Number: 117
Published online on: 20 April 2026

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Expression of Concern Open Access

[Expression of Concern] Adenovirus‑mediated truncated Bid overexpression induced by the Cre/LoxP system promotes the cell apoptosis of CD133+ ovarian cancer stem cells

Qifang Long, Ru Yang, Weixian Lu, Weipei Zhu, Jundong Zhou, Cui Zheng, Dongmei Zhou, Ling Yu, Jinchang Wu
Article Number: 116
Published online on: 15 April 2026

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Review Open Access

Incorporating artificial intelligence into morphological diagnosis of acute leukemias: Current landscape, challenges and prospects (Review)

Hui Cheng, Guodong Zheng, Yuanyuan Yang, Chun Xu, Gusheng Tang, Chongmei Huang
Article Number: 115
Published online on: 15 April 2026

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Article Open Access

Mechanistic study of MUC3A in promoting progression of clear cell renal cell carcinoma via the JAK‑STAT pathway

Yongyang Yun, Xing Ji, Shuai Hu, Tianyu Wu, Yixiao Liu, Zheng Li, Zhoujie Sun, Peimin Zhou, Lei Yang, Wei Yu
Article Number: 114
Published online on: 14 April 2026

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Article Open Access

Perturbation of BRD4 and p300 activity suppresses super enhancer‑driven KLF6 expression in renal carcinoma

Nurul Nadia Mohamad Zamberi, Asmaa Y. Abuhamad, Siti Nur Hasanah Mohd Yusuf, Nur Qurratu Athirah A. Rahman, Mohamad Aimanuddin Mohtar, Saiful Effendi Syafruddin
Article Number: 113
Published online on: 14 April 2026

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Article Open Access

PINK1‑mediated mitophagy enhances breast cancer proliferation through metabolic reprogramming

Zong Jin Guo, Qian Yu, Rui Sha, Wei Li, Hui Juan Dai
Article Number: 112
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Metformin inhibits growth and sensitizes osteosarcoma cell lines to cisplatin through cell cycle modulation

Irene Quattrini, Amalia Conti, Laura Pazzaglia, Chiara Novello, Stefano Ferrari, Piero Picci, Maria Serena Benassi
Article Number: 111
Published online on: 08 April 2026

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Article Open Access

NF‑κB‑driven LUZP1 promotes metastasis and chemoresistance in head and neck squamous cell carcinoma

Chen-Yuan Lin, Ching-Yun Hsieh, Hsin-Chi Lan, Ching-Chan Lin, Tzu-Ting Chen, Wei-Chi Tseng, Yung-An Tsou, Wei-Chao Chang
Article Number: 110
Published online on: 07 April 2026

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Article Open Access

Hypoxic CAF studies unveil PTHrP‑vitamin D‑RAS axis as pivotal in the CAF

Shoichiro Nakajo, Mamoru Uemura, Hiroshi Kusafuka, Mao Osaki, Chikako Kusunoki, Nobuo Takiguchi, Mitsunobu Takeda, Yuki Sekido, Tsuyoshi Hata, Atsushi Hamabe, Takayuki Ogino, Norikatsu Miyoshi, Mitsuyoshi Tei, Yoshinori Kagawa, Hirofumi Yamamoto, Yuichiro Doki, Hidetoshi Eguchi
Article Number: 109
Published online on: 07 April 2026

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Retraction Open Access

[Retracted] miR‑24‑3p regulates bladder cancer cell proliferation, migration, invasion and autophagy by targeting DEDD

Guoqiang Yu, Zhaohui Jia, Zhongling Dou
Article Number: 108
Published online on: 06 April 2026

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Review Open Access

Role of CHD4 in tumor progression, DNA damage response and treatment resistance (Review)

Shuo Li, Quan Ma, Keying Lian, Zhisheng Jiang, Yun Ma
Article Number: 107
Published online on: 02 April 2026

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Review Open Access

T cell fate regulation in EBV‑associated nasopharyngeal carcinoma (Review)

Liuyang Zhang, Shun Ding, Dongzhui Chen, Benchi Cai, Zhonglin Mu
Article Number: 106
Published online on: 02 April 2026

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Retraction Open Access

[Retracted] Ultrasound‑targeted microbubble destruction‑mediated overexpression of Sirtuin 3 inhibits the progression of ovarian cancer

Li Cheng, Dongmei Zhang, Wei Yan
Article Number: 105
Published online on: 02 April 2026

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Review Open Access

HMGB3: A pivotal orchestrator of therapy resistance and cancer stemness in human malignancies (Review)

Ju Zhang, Yifan Sun, Lanyu Wang, Jiayu Gu, Ye Hua, Jianfeng Shao, Ninghan Feng
Article Number: 104
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] 5‑Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene

Xiaorong Wang, E. Chen, Xue Yang, Yin Wang, Zhen Quan, Xiaohou Wu, Chunli Luo
Article Number: 103
Published online on: 30 March 2026

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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