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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2008 Volume 19 Issue 6

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Highlighting the immunohistochemical profile of melanocytomas (Review)

Pascale Quatresooz, Claudine Piérard-Franchimont, Gérald E. Piérard
Pages: 1367-1372
Published online on: 01 June 2008

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Article

Tumor risk assessment by means of immunocytochemical detection of early pre-malignant changes in buccal smears

Marc M. Bloching, Hannah Soulsby, Andreas Naumann, Wolfram Aust, Daniel Merkel, Theresa Braun, Ramin Naim
Pages: 1373-1379
Published online on: 01 June 2008

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Article

ERAP140/Nbla10993 is a novel favorable prognostic indicator for neuroblastoma induced in response to retinoic acid

Hiroshi Arai, Toshinori Ozaki, Hidetaka Niizuma, Yohko Nakamura, Miki Ohira, Kunio Takano, Masahiko Matsumoto, Akira Nakagawara
Pages: 1381-1388
Published online on: 01 June 2008

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Article

New radiosensitization treatment (KORTUC I) using hydrogen peroxide solution-soaked gauze bolus for unresectable and superficially exposed neoplasms

Yasuhiro Ogawa, Hironobu Ue, Kazuhiro Tsuzuki, Michiko Tadokoro, Kana Miyatake, Toshikazu Sasaki, Norikazu Yokota, Norihiko Hamada, Shinji Kariya, Jiro Hitomi, Akihito Nishioka, Kimiko Nakajima, Mitsunori Ikeda, Shigetoshi Sano, Taisuke Inomata
Pages: 1389-1394
Published online on: 01 June 2008

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Article

Efficacy of oncolytic reovirus against human breast cancer cells

Yoko Hata, Tsuyoshi Etoh, Masafumi Inomata, Norio Shiraishi, Akira Nishizono, Seigo Kitano
Pages: 1395-1398
Published online on: 01 June 2008

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Article

A fraction of methylene chloride from Geum japonicum Thunberg inhibits tumor metastatic and angiogenic potential

Jin-Chul Heo, Minsik Son, Sang-Uk Woo, Mi-Ae Kweon, Eun Kyung Yoon, Hee Kyung Lee, Won-Sik Choi, Kang-Jin Cho, Sang-Han Lee
Pages: 1399-1403
Published online on: 01 June 2008

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Article

Decreased expression of the thyroid-stimulating hormone receptor in poorly-differentiated carcinoma of the thyroid

Hirofumi Matsumoto, Atsuhiko Sakamoto, Masachika Fujiwara, Yukiko Yano, Yukiko Shishido-Hara, Yasunori Fujioka, Hiroshi Kamma
Pages: 1405-1411
Published online on: 01 June 2008

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Article

Comparison of Epstein-Barr virus genotypes and clinicohistopathological features of nasopharyngeal carcinoma between Guilin, China and Fukuoka, Japan

Yingqiong Zhou, Kazuki Nabeshima, Kaori Koga, Mikiko Aoki, Hiroyuki Hayashi, Makoto Hamasaki, Hiroshi Iwasaki
Pages: 1413-1420
Published online on: 01 June 2008

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Article

Loss of CYLD might be associated with development of salivary gland tumors

Masakatsu Fukuda, Miki Hiroi, Seiji Suzuki, Yoshihiro Ohmori, Hideaki Sakashita
Pages: 1421-1427
Published online on: 01 June 2008

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Article

PTEN expression and methylation status in oral squamous cell carcinoma

Yoshinori Kurasawa, Masashi Shiiba, Megumi Nakamura, Kazuaki Fushimi, Takashi Ishigami, Hiroki Bukawa, Hidetaka Yokoe, Katsuhiro Uzawa, Hideki Tanzawa
Pages: 1429-1434
Published online on: 01 June 2008

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Article

Comparison of histologic subtype and growth pattern in intraductal papillary-mucinous carcinoma of the pancreas

Yuichi Sanada, Satoko Kunita, Kazuhiro Yoshida
Pages: 1435-1443
Published online on: 01 June 2008

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Article

HER-2 peptides p776 and F7, N-terminal-linked with Ii-Key tetramer (LRMK) help the proliferation of E75-TCR+ cells: The dependency of help on the side chains of LRMK-extended peptide pointed towards the T cell receptor

Yufeng Li, Satoshi Ishiyama, Satoko Matsueda, Naotake Tsuda, Constantin G. Ioannides
Pages: 1445-1452
Published online on: 01 June 2008

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Article

HLA-B gene participates in the NF-κB signal pathway partly by regulating S100A8 in the laryngeal carcinoma cell line Hep2

Yan Guo, Jia Liu, Zhenming Xu, Kailai Sun, Weineng Fu
Pages: 1453-1459
Published online on: 01 June 2008

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Article

Association between the expression of chemokine receptors CCR7 and CXCR3, and lymph node metastatic potential in lung adenocarcinoma

Shinichi Maekawa, Akinori Iwasaki, Takayuki Shirakusa, Takehito Kawakami, Jun Yanagisawa, Toshihiro Tanaka, Hirotomo Shibaguchi, Testushi Kinugasa, Motomu Kuroki, Masahide Kuroki
Pages: 1461-1468
Published online on: 01 June 2008

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Article

Evidence of chromosomal alterations in pure usual ductal hyperplasia as a breast carcinoma precursor

Shu Xu, Bing Wei, Hongying Zhang, Mingxia Qing, Hong Bu
Pages: 1469-1475
Published online on: 01 June 2008

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Article

The overexpression of c-met as a prognostic indicator for gastric carcinoma compared to p53 and p21 nuclear accumulation

Uta Drebber, Stephan E. Baldus, Britt Nolden, Guido Grass, Elfriede Bollschweiler, Hans P. Dienes, Arnulf H. Hölscher, Stefan P. Mönig
Pages: 1477-1483
Published online on: 01 June 2008

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Article

The cellular localization of autotaxin impacts on its biological functions in human thyroid carcinoma cells

Anja Seifert, Thomas Klonisch, Jens Wulfaenger, Friedrich Haag, Henning Dralle, Jürgen Langner, Cuong Hoang-Vu, Astrid Kehlen
Pages: 1485-1491
Published online on: 01 June 2008

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Article

Anticancer effect of SN-38 on colon cancer cell lines with different metastatic potential

Åsa Wallin, Joar Svanvik, Birgitta Holmlund, Lillianne Ferreud, Xiao-Feng Sun
Pages: 1493-1498
Published online on: 01 June 2008

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Article

Down-regulation of Mcl-1 with antisense technology alters the effect of various cytotoxic agents used in treatment of squamous cell carcinoma of the head and neck

Christiane Skoda, Boban M. Erovic, Volker Wachek, Laurenz Vormittag, Fritz Wrba, Helga Martinek, Gregor Heiduschka, Philipp Kloimstein, Edgar Selzer, Dietmar Thurnher
Pages: 1499-1503
Published online on: 01 June 2008

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Article

Contribution of mutations in ATM to breast cancer development in the Czech population

Jana Soukupova, Pavel Dundr, Zdenek Kleibl, Petr Pohlreich
Pages: 1505-1510
Published online on: 01 June 2008

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Article

Pharmacological separation of hEAG and hERG K+ channel function in the human mammary carcinoma cell line MCF-7

Jeremy Roy, Brenna Vantol, Elizabeth A. Cowley, Jonathan Blay, Paul Linsdell
Pages: 1511-1516
Published online on: 01 June 2008

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Article

CI-994 (N-acetyl-dinaline) in combination with conventional anti-cancer agents is effective against acute myeloid leukemia in vitro and in vivo

I. Hubeek, E. M. Comijn, C. L. Van der Wilt, R. L. Merriman, J. M. Padron, G. J.L. Kaspers, G. J. Peters
Pages: 1517-1523
Published online on: 01 June 2008

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Article

A single institutional experience of surgically resected thymic epithelial tumors over 10 years - Clinical outcomes and clinicopathologic features

Beom Kyung Kim, Byoung Chul Cho, Hye Jin Choi, Joo Hyuk Sohn, Moo Suk Park, Joon Chang, Se Kyu Kim, Dae Joon Kim, Kyung Young Chung, Chang Geol Lee, Joo Hang Kim, Nae Choon Yoo
Pages: 1525-1531
Published online on: 01 June 2008

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Article

Decorin suppresses lung metastases of murine osteosarcoma

Ken Shintani, Akihiko Matsumine, Katsuyuki Kusuzaki, Joji Morikawa, Takao Matsubara, Toru Wakabayashi, Kentaro Araki, Haruhiko Satonaka, Hiroki Wakabayashi, Takahiro Iino, Atsumasa Uchida
Pages: 1533-1539
Published online on: 01 June 2008

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Article

Mutations of epidermal growth factor receptor in colon cancer indicate susceptibility or resistance to gefitinib

Xiang Zhang, Hisashi Nagahara, Koshi Mimori, Hiroshi Inoue, Tetsuji Sawada, Masaichi Ohira, Kosei Hirakawa, Masaki Mori
Pages: 1541-1544
Published online on: 01 June 2008

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Article

Impact of mitochondrial DNA on hypoxic radiation sensitivity in human fibroblast cells and osteosarcoma cell lines

Hideya Yamazaki, Ken Yoshida, Yasuo Yoshioka, Fumiaki Isohashi, Shuji Ozeki, Masahiko Koizumi, Makoto Yoneda, Takehiro Inoue
Pages: 1545-1549
Published online on: 01 June 2008

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Article

A phase II multicenter trial of concurrent chemoradiotherapy with weekly nedaplatin in advanced uterine cervical carcinoma: Tohoku Gynecologic Cancer Unit Study

Yoshihito Yokoyama, Tadao Takano, Kenji Nakahara, Tadahiro Shoji, Hirokazu Sato, Hidekazu Yamada, Nobuo Yaegashi, Kunihiro Okamura, Hirohisa Kurachi, Toru Sugiyama, Toshinobu Tanaka, Akira Sato, Toru Tase, Hideki Mizunuma
Pages: 1551-1556
Published online on: 01 June 2008

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Article

Expression of epiregulin, a novel epidermal growth factor ligand associated with prognosis in human oral squamous cell carcinomas

Hideo Shigeishi, Koichiro Higashikawa, Misato Hiraoka, Shinichi Fujimoto, Yoshitsugu Mitani, Kouji Ohta, Masaaki Takechi, Nobuyuki Kamata
Pages: 1557-1564
Published online on: 01 June 2008

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Article

Effect of cranberry juice concentrate on chemically-induced urinary bladder cancers

Jeevan K. Prasain, Kenneth Jones, Ray Moore, Stephen Barnes, Marge Leahy, Robin Roderick, M. Margaret Juliana, Clinton J. Grubbs
Pages: 1565-1570
Published online on: 01 June 2008

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Article

Expression of the hMLH1 gene is a possible predictor for the clinical response to 5-fluorouracil after a surgical resection in colorectal cancer

Takao Ide, Yoshihiko Kitajima, Kazuma Ohtaka, Mayumi Mitsuno, Yuji Nakafusa, Kohji Miyazaki
Pages: 1571-1576
Published online on: 01 June 2008

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Article

Specific proteolysis of the A-kinase-anchoring protein 149 at the Asp582 residue by caspases during apoptosis

Hoesook Yoo, Hwa Jun Cha, Joonyoung Lee, Eun-Ok Yu, Seunghee Bae, Jin Hyuk Jung, Insook Sohn, Su-Jae Lee, Kwang-Hee Yang, Sang-Hyeok Woo, Sung-Keum Seo, In-Chul Park, Chong Soon Kim, Young-Woo Jin, Sung K. Ahn
Pages: 1577-1582
Published online on: 01 June 2008

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Article

Inhibitory effect of voluntary running wheel exercise on the growth of human pancreatic Panc-1 and prostate PC-3 xenograft tumors in immunodeficient mice

Xi Zheng, Xiao-Xing Cui, Mou-Tuan Huang, Yue Liu, Weichung Joe Shih, Yong Lin, Yao Ping Lu, George C. Wagner, Allan H. Conney
Pages: 1583-1588
Published online on: 01 June 2008

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Article

A study on anti-tumor immunity induced by gene-modified melanoma B16 cells

Lijuan Fang, Kemin Wang, Xia Liu, Leilei Zhang, Xingqian Zhang, Li Qian, Jian Lu, Guanxiang Qian, Shengfang Ge
Pages: 1589-1595
Published online on: 01 June 2008

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Article

A cyclic peptide derived from α-fetoprotein inhibits the proliferative effects of the epidermal growth factor and estradiol in MCF7 cells

Cristian Torres, Elmer Antileo, Maráa José Epuñán, Ana María Pino, Luis Emilio Valladares, Walter Daniel Sierralta
Pages: 1597-1603
Published online on: 01 June 2008

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Article

Telomere length and radiosensitivity in human fibroblast clones immortalized by ectopic telomerase expression

Samantha Zongaro, Annalisa Verri, Elena Giulotto, Chiara Mondello
Pages: 1605-1609
Published online on: 01 June 2008

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Article

Apoptosis in B-CLL: The relationship between higher ex vivo spontaneous apoptosis before treatment in III-IV Rai stage patients and poor outcome

Malgorzata Sieklucka, Piotr Pozarowski, Agnieszka Bojarska-Junak, Iwona Hus, Anna Dmoszynska, Jacek Rolinski
Pages: 1611-1620
Published online on: 01 June 2008

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Article

Novel resveratrol analogs induce apoptosis and cause cell cycle arrest in HT29 human colon cancer cells: Inhibition of ribonucleotide reductase activity

Philipp Saiko, Michael Pemberger, Zsuzsanna Horvath, Ivo Savinc, Michael Grusch, Norbert Handler, Thomas Erker, Walter Jaeger, Monika Fritzer-Szekeres, Thomas Szekeres
Pages: 1621-1626
Published online on: 01 June 2008

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Article

Progestins regulate genes that can elicit both proliferative and antiproliferative effects in breast cancer cells

Sami Purmonen, Tommi Manninen, Pasi Pennanen, Timo Ylikomi
Pages: 1627-1634
Published online on: 01 June 2008

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Journal Cover
September-2026 Volume 56 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Polyphyllin II inhibits thyroid cancer progression by targeting HRH1 and suppressing Wnt/β‑catenin signaling

Jianwei Sun, Haifeng Liang, Yan Zhang, Ding Ding, Qian Xiang, Mengyang Zheng, Pengyue Zhang
Article Number: 163
Published online on: 23 July 2026

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Review Open Access

Multidimensional molecular mechanisms of drug resistance in breast cancer: Implications for clinical decision‑making and treatment strategies (Review)

Wenya Xu, Shiyao Kang, Shaochen Xin, Yanbin Wu, Yuan Zhao, Miaomiao Sheng
Article Number: 162
Published online on: 22 July 2026

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Review Open Access

XPO1: From basic research to clinical treatment (Review)

Changyan Yang, Jing Zhu, Xiang Zheng, Xiaochen Hou, Jiumei Zhao, Youfu Pan, Yu Tang
Article Number: 161
Published online on: 22 July 2026

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Retraction Open Access

[Retracted] Methylation and intratumoural heterogeneity of 14‑3‑3 σ in oral cancer

Ujjal Kumar Bhawal, Keiichi Tsukinoki, Tomonori Sasahira, Fuyuki Sato, Yusuke Mori, Noriko Muto, Masaru Sugiyama, Hiroki Kuniyasu
Article Number: 160
Published online on: 20 July 2026

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Article Open Access

M2‑TAM‑derived exosomal miR‑491‑3p modulates UBE2D3 and promotes the proliferation, migration and invasion of lung cancer cells

Qiang Zhang, Yungang Sun, Yu Zhuang, Shiwei Xu, Mengxu Yao, Siyang Jiao, Qi Wang, Feng Shao, Xiaoying Zhang
Article Number: 159
Published online on: 17 July 2026

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Correction Open Access

[Corrigendum] Emodin attenuated severe acute pancreatitis via the P2X ligand‑gated ion channel 7/NOD‑like receptor protein 3 signaling pathway

Qingkai Zhang, Xufeng Tao, Shilin Xia, Jialin Qu, Huiyi Song, Jianjun Liu, Hailong Li, Dong Shang
Article Number: 158
Published online on: 15 July 2026

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Article Open Access

TM6SF2 overexpression suppresses the proliferation and promotes apoptosis of human hepatocellular carcinoma cells

Ziyou Huai, Wanying Xue, Xinxiao Jin, Shiyu Peng, Wenqiang Xu, Shujing Li, Huanfeng Hao, Yuanyuan Wang
Article Number: 157
Published online on: 14 July 2026

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Correction Open Access

[Corrigendum] VDAC upregulation and αTAT1‑mediated α‑tubulin acetylation contribute to tanespimycin‑induced apoptosis in Calu‑1 cells

Qilin Wang, Xiangguo Liu
Article Number: 156
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells

Annamaria Spina, Luca Sorvillo, Emilio Chiosi, Antonietta Esposito, Francesca Di Maiolo, Luigi Sapio, Michele Caraglia, Silvio Naviglio
Article Number: 155
Published online on: 06 July 2026

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Article Open Access

Identification of RRM2 as a key regulator of malignant epithelial cells in gastric cancer through single‑cell transcriptomics

Xinzhen Cai, Yun He, Lili Kang, Dongli Zhou, Mengmeng Wang, Tianyu Ma
Article Number: 154
Published online on: 03 July 2026

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Article

Impact of WFDC2 on the biological functions of cervical cancer cells and the regulation of the ERK/NF‑κB signaling pathway

Yanping Zhang, Hongling Zou, Shufeng Deng, Lvling Zou, Mingzhu Xia, Limin Tao
Article Number: 153
Published online on: 01 July 2026

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review)

Shujing Xia, Xiumei Zhang, Lizhong Tang, Anqi Li, Jianhai Chen, Zhang Tao
Article Number: 174
Published online on: 14 August 2026

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Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

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Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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