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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2011 Volume 25 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

High-level expression of podoplanin in benign and malignant soft tissue tumors: Immunohistochemical and quantitative real-time RT-PCR analysis

Yongjun Xu, Akira Ogose, Hiroyuki Kawashima, Tetsuo Hotta, Takashi Ariizumi, Guidong Li, Hajime Umezu, Naoto Endo
Pages: 599-607
Published online on: 13 January 2011

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Expression of junB is markedly stimulated by glycyrrhizin in a human hepatoma cell line. Erratum in /or/31/2/1030

Katsuro Koike
Pages: 609-617
Published online on: 10 January 2011

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Article

Leukocyte adhesion-GPCR EMR2 is aberrantly expressed in human breast carcinomas and is associated with patient survival

John Q. Davies, Hsi-Hsien Lin, Martin Stacey, Simon Yona, Gin-Wen Chang, Siamon Gordon, Jörg Hamann, Leticia Campo, Cheng Han, Peter Chan, Stephen B. Fox
Pages: 619-627
Published online on: 21 December 2010

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Differential gene expression during colon-to-lung metastasis

Sung-Hyun Kim, So-Jung Choi, Yong Beom Cho, Min-Woong Kang, Jinseon Lee, Woo-Yong Lee, Ho Kyung Chun, Yong Soo Choi, Hong Kwan Kim, Jungho Han, Jhingook Kim
Pages: 629-636
Published online on: 13 January 2011

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Article

Upregulation of thioredoxin reductase 1 in human oral squamous cell carcinoma

Shunichiro Iwasawa, Yukio Yamano, Yuichi Takiguchi, Hideki Tanzawa, Koichiro Tatsumi, Katsuhiro Uzawa
Pages: 637-644
Published online on: 30 December 2010

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Proteasome inhibitor sensitizes oral squamous cell carcinoma cells to TRAIL-mediated apoptosis Retraction in /10.3892/or.2023.8519

Sayaka Yoshiba, Masayasu Iwase, Sayaka Kurihara, Makiko Uchida, Yuji Kurihara, Hitoshi Watanabe, Satoru Shintani
Pages: 645-652
Published online on: 28 December 2010

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Heme oxygenase-1 promotes angiogenesis in urothelial carcinoma of the urinary bladder

Makito Miyake, Kiyohide Fujimoto, Satoshi Anai, Sayuri Ohnishi, Masaomi Kuwada, Yasushi Nakai, Takeshi Inoue, Yoshiaki Matsumura, Atsushi Tomioka, Tomohiro Ikeda, Nobumichi Tanaka, Yoshihiko Hirao
Pages: 653-660
Published online on: 27 December 2010

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Article

ABT-263, a Bcl-2 inhibitor, enhances the susceptibility of lung adenocarcinoma cells treated with Src inhibitors to anoikis

Yuji Sakuma, Jun Tsunezumi, Yoshiyasu Nakamura, Mitsuyo Yoshihara, Shoichi Matsukuma, Shiro Koizume, Yohei Miyagi
Pages: 661-667
Published online on: 27 December 2010

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Molecular characterization of late stomal recurrence following total laryngectomy

Josena K. Stephen, Mausumi Symal, Kang Mei Chen, Tamer Ghanem, Robert Deeb, Veena Shah, Shaleta Havard, Maria J. Worsham
Pages: 669-676
Published online on: 10 January 2011

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Suppressor of cytokine signaling 1 interacts with oncogenic lymphocyte-specific protein tyrosine kinase

Srividya Venkitachalam, Fu-Yu Chueh, King-Fu Leong, Samantha Pabich, Chao-Lan Yu
Pages: 677-683
Published online on: 13 January 2011

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A haplotype of TGFBR1 is predominantly found in non-small cell lung cancer patients displaying TGFBR1 allelic-specific expression

Jinxia Sun, Zhe Lei, Reng-Yun Liu, Yufeng Lu, Zhixiang Zhuang, Xiefang Jiang, Qian Qian, Zeyi Liu, Jun Zhao, Hong-Tao Zhang
Pages: 685-691
Published online on: 10 January 2011

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ERCC1 protein, mRNA expression and T19007C polymorphism as prognostic markers in head and neck squamous cell carcinoma patients treated with surgery and adjuvant cisplatin-based chemoradiation

Gilberto De Castro , Fatima Solange Pasini, Sheila Aparecida Coelho Siqueira, Alberto Rossetti Ferraz, Rosangela Correa Villar, Igor Moysés Longo Snitcovsky, Miriam Hatsue Honda Federico
Pages: 693-699
Published online on: 03 January 2011

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CD133 is a temporary marker of cancer stem cells in small cell lung cancer, but not in non-small cell lung cancer

Fei Cui, Jian Wang, Duan Chen, Yi-Jiang Chen
Pages: 701-708
Published online on: 20 December 2010

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Periostin, a matrix specific protein, is associated with proliferation and invasion of pancreatic cancer

Qi-Wen Ben, Xiao-Long Jin, Jun Liu, Xia Cai, Fei Yuan, Yao-Zong Yuan
Pages: 709-716
Published online on: 11 January 2011

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Genome-wide molecular characterization of mucinous colorectal adenocarcinoma using cDNA microarray analysis

Han Sang Kim, Seung Hui Kang, Chan Hee Park, Woo Ick Yang, Hei Cheul Jeung, Hyun Cheol Chung, Jae Kyung Roh, Joong Bae Ahn, Nam Kyu Kim, Byung Soh Min, Sun Young Rha
Pages: 717-727
Published online on: 27 December 2010

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CCL19-induced chemokine receptor 7 activates the phosphoinositide-3 kinase-mediated invasive pathway through Cdc42 in metastatic squamous cell carcinoma of the head and neck

Zhen-Jin Zhao, Fa-Yu Liu, Peng Li, Xue Ding, Zhi-Hong Zong, Chang-Fu Sun
Pages: 729-737
Published online on: 14 December 2010

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MicroRNA expression profiles in human colorectal cancers with liver metastases

Maosong Lin, Weichang Chen, Junxing Huang, Hengjun Gao, Yulan Ye, Zhenyun Song, Xiaoying Shen
Pages: 739-747
Published online on: 20 December 2010

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Exosomes in the ascites of ovarian cancer patients: origin and effects on anti-tumor immunity

Peng Peng, You Yan, Shen Keng
Pages: 749-762
Published online on: 22 December 2010

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Article

mTOR inhibitors show promising in vitro activity in bladder cancer and head and neck squamous cell carcinoma

Fiona Schedel, Ralph Pries, Beate Thode, Brigitte Wollmann, Sandra Wulff, Dieter Jocham, Barbara Wollenberg, Ingo Kausch
Pages: 763-768
Published online on: 14 January 2011

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Diverse sensitivity of cells representing various stages of colon carcinogenesis to increased extracellular zinc: Implications for zinc chemoprevention

Stanislav John, Tomás Briatka, Emil Rudolf
Pages: 769-780
Published online on: 27 December 2010

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Tanshinone IIA acts via p38 MAPK to induce apoptosis and the down-regulation of ERCC1 and lung-resistance protein in cisplatin-resistant ovarian cancer cells

Jin-Wen Jiao, Fang Wen
Pages: 781-788
Published online on: 13 December 2010

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Effect of classification based on combination of mutation and methylation in colorectal cancer prognosis

Haruhiko Aoyagi, Satoru Iida, Hiroyuki Uetake, Toshiaki Ishikawa, Yoko Takagi, Hirotoshi Kobayashi, Tetsuro Higuchi, Masamichi Yasuno, Masayuki Enomoto, Kenichi Sugihara
Pages: 789-794
Published online on: 21 December 2010

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Gene therapy for oral squamous cell carcinoma with IAI.3B promoter-driven oncolytic adenovirus-infected carrier cells

Ting Zhang, Katsuyuki Hamada, Masamitsu Hyodo, Hiroshi Itoh, Kenzaburo Tani, Hiroyuki Goda, Koh-Ichi Nakashiro, Hiroyuki Hamakawa
Pages: 795-802
Published online on: 30 December 2010

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Down-regulation of osteopontin inhibits metastasis of hepatocellular carcinoma cells via a mechanism involving MMP-2 and uPA

Rong-Xin Chen, Yun-Hong Xia, Tong-Chun Xue, Hong Zhang, Sheng-Long Ye
Pages: 803-808
Published online on: 21 December 2010

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Article

Functional effects of the MLH1-93G>A polymorphism on MLH1/EPM2AIP1 promoter activity

Sheron Perera, Miralem Mrkonjic, James B. Rawson, Bharati Bapat
Pages: 809-815
Published online on: 30 December 2010

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Article

Altered expression of imprinted genes in Wilms tumors

Jochen Hubertus, Martin Lacher, Marietta Rottenkolber, Josef Müller-Höcker, Michael Berger, Maximilian Stehr, Dietrich von Schweinitz, Roland Kappler
Pages: 817-823
Published online on: 20 December 2010

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Na+/K+-ATPase α3 mediates sensitivity of hepatocellular carcinoma cells to bufalin

Huaxing Li, Peng Wang, Yang Gao, Xiaoyan Zhu, Luming Liu, Lorenzo Cohen, Zhiqiang Meng, Peiying Yang
Pages: 825-830
Published online on: 22 December 2010

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Optimization of activation requirements of immature mouse dendritic JAWSII cells for in vivo application

Lukasz Zapala, Nadzieja Drela, Jacek Bil, Dominika Nowis, Grzegorz W. Basak, Witold Lasek
Pages: 831-840
Published online on: 28 December 2010

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Overexpression of Tiam1 predicts poor prognosis in patients with esophageal squamous cell carcinoma

Huaimin Liu, Guirong Shi, Xiaoli Liu, Hui Wu, Qinxia Fan, Xin Wang
Pages: 841-848
Published online on: 24 December 2010

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Article

RC-RNase-induced cell death in estrogen receptor positive breast tumors through down-regulation of Bcl-2 and estrogen receptor

Hsu-Hung Tseng, Yung-Luen Yu, Yi-Lin Sophia Chen, Jia-Hui Chen, Chu-Lin Chou, Tsun-Yung Kuo, Jaang-Jiun Wang, Ming-Chieh Lee, Ting-Han Huang, Mark Hung-Chih Chen, Giou-Teng Yiang
Pages: 849-853
Published online on: 20 December 2010

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Article

Effects of bevacizumab in mouse model of endometrial cancer: Defining the molecular basis for resistance

Suzy Davies, Donghai Dai, Gavin Pickett, Kristina W. Thiel, Victoria P. Korovkina, Kimberly K. Leslie
Pages: 855-862
Published online on: 14 January 2011

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Article

Penetration of paclitaxel and 5-fluorouracil in multicellular layers of human colorectal cancer cells

Mi-Sun Choi, Soo-Hyun Kim, Hyo-Jeong Kuh
Pages: 863-870
Published online on: 10 January 2011

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Article

The enhancement of propyl gallate-induced apoptosis in HeLa cells by a proteasome inhibitor MG132

Bo Ra You, Woo Hyun Park
Pages: 871-877
Published online on: 24 December 2010

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Article

Retrovirus-mediated transduction of a short hairpin RNA gene for GRP78 fails to downregulate GRP78 expression but leads to cisplatin sensitization in HeLa cells

Toshikazu Suzuki, Jun Lu, Gaofeng Hu, Kazuko Kita, Nobuo Suzuki
Pages: 879-885
Published online on: 10 January 2011

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Article

The microtubule inhibiting agent epothilone B antagonizes glioma cell motility associated with reorganization of the actin-binding protein α-actinin 4

Whitney I. Henry, Juwen Dubois, Quincy A. Quick
Pages: 887-893
Published online on: 13 January 2011

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Genomic instability, postoperative recurrence and therapeutic vulnerabilities in resectable non‑small cell lung cancer (Review)

Linlin Wang, Yong Feng, Qiang Liu
Article Number: 182
Published online on: 28 August 2026

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Review Open Access

Research progress on lactate metabolism in lung cancer: Tumorigenesis, drug resistance and clinical translation (Review)

Yuantao Zhang, Yiyang Shang, Hai Zeng, Ruiling Ning, Xinran Zhang, Dongxu Ao, Jun Cai, Qingqing Ye
Article Number: 181
Published online on: 28 August 2026

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Decoding the metabolic‑immune crosstalk: The role of glutamine and ammonium reprogramming in prostate cancer immune evasion (Review)

Peilong Wang, Xiaoran Li, Teng Ma, Jun Mi
Article Number: 180
Published online on: 27 August 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells

Jing Guo, Li Chen, Ning Luo, Weihong Yang, Xiaoyan Qu, Zhongping Cheng
Article Number: 179
Published online on: 24 August 2026

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Article Open Access

Combination of lonidamine with devimistat induces synergistic antitumor effects in lung cancer via multifaceted disruption of cellular energy metabolism

Xinhe Bai, Yongfeng Yang, Yuling Luo, Pei Jing, Xia Hong, Yaqin Zou, Yan Dai, Xuping Yang, Meiling Zhou, Han Xiao, Yilan Huang, Shiwei Guo, Qingze Fan
Article Number: 178
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Targeting ribonucleotide reductase M2 subunit by small interfering RNA exerts anti‑oncogenic effects in gastric adenocarcinoma 

Wei Kang, Joanna H.M. Tong, Anthony W.H. Chan, Junhong Zhao, Shiyan Wang, Yujuan Dong, Frankie M.C. Sin, Saifung Yeung, Alfred S.L. Cheng, Jun Yu, Kafai To
Article Number: 177
Published online on: 20 August 2026

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Article Open Access

Cancer‑associated fibroblast‑derived extracellular vesicles promote pancreatic cancer progression via the RAP1B/ANLN axis

Daigo Yoshimori, Mitsuhiro Kudo, Kousuke Ishino, Junji Ueda, Yukako Shintani-Domoto, Akira Matsushita, Youichi Kawano, Takashi Ono, Takahiro Haruna, Kazuhiko Endo, Akira Hamaguchi, Takenori Fujii, Yoko Kawamoto, Kiyoshi Teduka, Taeko Kitamura, Atsushi Masamune, Akihisa Matsuda, Hiroshi Yoshida, Ryuji Ohashi
Article Number: 176
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Restoration of the tumor‑suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells

Dan Jiang, Lingyao Wang, Tong Zhao, Zhaoyu Zhang, Renxia Zhang, Jingji Jin, Yong Cai, Fei Wang
Article Number: 175
Published online on: 17 August 2026

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Review Open Access

Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review)

Shujing Xia, Xiumei Zhang, Lizhong Tang, Anqi Li, Jianhai Chen, Zhang Tao
Article Number: 174
Published online on: 14 August 2026

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Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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Journal Cover
November-2026 Volume 56 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Correction Open Access

[Corrigendum] High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer

Yahua Chen, Jun Liu, Wei Wang, Li Xiang, Jide Wang, Side Liu, Hongyan Zhou, Zheng Guo
Article Number: 192
Published online on: 21 September 2026

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Review Open Access

Overcoming melanoma drug resistance: Mechanisms and clinical progress of oncolytic viruses combined with immune checkpoint inhibitors (Review)

Yuan He, Wenxuan Lin, Haofang Chen, Yongqi Guan, Congcong Guan, Yanxiang Zhang, Dongsheng Pan
Article Number: 191
Published online on: 17 September 2026

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Validation of next‑generation sequencing‑derived circulating mRNA variants as potential diagnostic tools in hepatocellular carcinoma and cholangiocarcinoma

Daniel Zezulinski, Maarouf A. Hoteit, David E. Kaplan, Tingting Zhan, Cataldo Doria, Timothy M. Block, Aejaz Sayeed
Article Number: 190
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] The interaction between miR‑148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer

Le Hong, Gen Sun, Long Peng, Yi Tu, Zhen Wan, Haiwei Xiong, Yong Li, Weidong Xiao
Article Number: 189
Published online on: 16 September 2026

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Expression of Concern Open Access

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Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo activities of an antitumor peptide HM‑3: A special dose‑efficacy relationship on an HCT‑116 xenograft model in nude mice

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Published online on: 08 September 2026

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Correction Open Access

[Corrigendum] TGF‑β1 mediates epithelial to mesenchymal transition via the TGF‑β/Smad pathway in squamous cell carcinoma of the head and neck

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