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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
Jul-Aug 1999 Volume 6 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Polypoid dysplasias in ulcerative colitis and sporadic adenomas: genetic approach to the differential diagnosis (review).

F Fogt, N Alsaigh
Pages: 721-726
Published online on: 01 July 1999

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Article

Changes in the findings of dynamic MRI by preoperative CAF chemotherapy for patients with breast cancer of stage II and III: pathologic correlation.

N Tsuboi, Y Ogawa, T Inomata, D Yoshida, S Yoshida, T Moriki, M Kumon
Pages: 727-759
Published online on: 01 July 1999

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Article

Inhibition of peripheral blood lymphocyte apoptosis by soluble fas ligand in patients with hepatocellular carcinoma.

Y Nakamoto, S Kaneko, S W Buttner, E Matsushita, K Kobayashi
Pages: 733-742
Published online on: 01 July 1999

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Article

Heterozygous ras mutations are preserved in serially passaged human tumor xenografts and established cell lines.

K Masuda, H Kijima, H M Kim, S B Han, Y Ohnishi, N Sawa, Y Oshika, T Tokunaga, T Tsuchida, Y Abe, T Hamana, H Matsubayashi, H Yamazaki, N Tamaoki, Y Ueyama, M Nakamura
Pages: 741-746
Published online on: 01 July 1999

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Article

The NM23 gene and its expression in oral squamous cell carcinoma.

L Lo Muzio, M D Mignogna, G Pannone, S Staibano, M Procaccini, R Serpico, G De Rosa, C Scully
Pages: 747-798
Published online on: 01 July 1999

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Article

Kinetic patterns in advanced gastric cancer as related to histotype and tumor extension.

D Spina, C Vindigni, L Presenti, A V Lalinga, M Stumpo, F Roviello, E Pinto, P Tosi
Pages: 753-760
Published online on: 01 July 1999

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Article

Time until initiation of tumor growth is an effective measure of the anti-angiogenic effect of TNP-470 on human glioblastoma in nude mice.

M Kragh, M Spang-Thomsen, P E Kristjansen
Pages: 759-821
Published online on: 01 July 1999

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Article

Unilateral metachronous lung cancers in a patient with idiopathic pulmonary fibrosis.

K Kirishima, H Satoh, Y T Yamashita, M Ohtsuka, K Sekizawa
Pages: 763-768
Published online on: 01 July 1999

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Article

Highly aggressive behavior and poor prognosis of small cell carcinoma in the stomach: flow cytometric and immunohistochemical analysis.

H Kimura, K Konishi, M Kaji, K Maeda, K Yabushita, M Tsuji, A Miwa
Pages: 767-839
Published online on: 01 July 1999

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Article

Anti-telomerase therapy suppressed glioma proliferation.

F Yamaguchi, R S Morrison, H Takahashi, A Teramoto
Pages: 773-779
Published online on: 01 July 1999

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Article

Changes of host natural killer cell activity in F344 rats during gastric carcinogenesis induced by N-methylnitrosourea.

G Choe, Y Lee, W Hong, M Lee, J Jang
Pages: 777-857
Published online on: 01 July 1999

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Article

Atypical presentation of vertebral bone metastasis from lung cancer.

T Nishino, A Yoshida, H Satoh, M Hagiya, T Sakamoto, Y T Yamashita, M Ohtsuka
Pages: 781-784
Published online on: 01 July 1999

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Article

Allelic loss on the short arm of chromosome 8 in oral squamous cell carcinoma.

K Ono, A Miyakawa, M Fukuda, M Shiiba, K Uzawa, T Watanabe, T Miya, H Yokoe, Y Imai, H Tanzawa
Pages: 785-794
Published online on: 01 July 1999

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Article

Patient survival and microsatellite instability in gliomas by high-resolution fluorescent analysis.

M Mizoguchi, T Inamura, K Ikezaki, T Iwaki, S Oda, Y Maehara, E Oki, M Terasaki, M Fukui
Pages: 791-796
Published online on: 01 July 1999

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Article

Paclitaxel combined with cis-platin as second-line treatment in patients with advanced non-small cell lung cancers refractory to cis-platin.

G P Stathopoulos, S Rigatos, N A Malamos
Pages: 797-1597
Published online on: 01 July 1999

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Article

Conservation treatment intensified with tamoxifen and CAF chemotherapy without axillary dissection for early breast cancer patients with clinically-negative axillary nodes.

Y Ogawa, A Nishioka, T Inomata, N Yokota, T Sasaki, M Terashima, S Yoshida, Y Tanaka, N Tohchika
Pages: 801-806
Published online on: 01 July 1999

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Article

Prognostic significance of serum LDH in Ewing's sarcoma of bone.

G Bacci, S Ferrari, A Longhi, S Rimondini, M Versari, A Zanone, C Forni
Pages: 807-818
Published online on: 01 July 1999

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Article

Modulation of neoangiogenesis in bronchial preneoplastic lesions.

G Fontanini, A Calcinai, L Boldrini, M Lucchi, A Mussi, C A Angeletti, C Cagno, M A Tognetti, F Basolo
Pages: 813-820
Published online on: 01 July 1999

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Article

Prognostic significance of different biomarkers in non-small cell lung cancer.

A M Lavezzi, L Santambrogio, N Bellaviti, B Biondo, M Nosotti, F Radice, L Matturri
Pages: 819-844
Published online on: 01 July 1999

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Article

Activity of glycogen synthase kinase-3beta is down-regulated during transient differentiation of human colon cancer HT-29 cells.

Z Tuhackova, E Sloncova, J Hlavacek, V Sovova, J Velek
Pages: 827-859
Published online on: 01 July 1999

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Article

Diagnosis of malignant pleural mesothelioma by supraclavicular lymph node biopsy.

M Huncharek, D Adcock
Pages: 833-837
Published online on: 01 July 1999

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Article

Flow cytometric analysis of Ki-67 in invasive ductal carcinoma of the breast: correlation with tumor and patient characteristics.

K Steck, K Hunt, S Tucker, S Singletary, A K El-Naggar
Pages: 835-843
Published online on: 01 July 1999

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Article

Prognostic relevance of microvessel density in colorectal tumours.

S A Abdalla, F Behzad, S Bsharah, S Kumar, S K Amini, S T O'Dwyer, N Y Haboubi
Pages: 839-881
Published online on: 01 July 1999

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Article

Effect of transforming growth factor-beta1 on oestrogen metabolism in MCF-7 and MDA-MB-231 breast cancer cell lines.

Y S Ee, L C Lai, K Reimann, P K Lim
Pages: 843-849
Published online on: 01 July 1999

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Article

Plant tannins as inhibitors of hydroperoxide production and tumor promotion induced by ultraviolet B radiation in mouse skin in vivo.

H U Gali-Muhtasib, S Z Yamout, M M Sidani
Pages: 847-900
Published online on: 01 July 1999

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Article

Early occurrence of an adenocarcinoma after allogeneic bone marrow transplantation in a patient with AML.

U Germing, G Kobbe, D Sohngen, H Motherby, S Braunstein, A Heyll, C Aul
Pages: 855-862
Published online on: 01 July 1999

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Article

High resolution mapping of chromosome 6 deletions in cervical cancer.

N Mazurenko, M Attaleb, T Gritsko, L Semjonova, L Pavlova, O Sakharova, F Kisseljov
Pages: 859-922
Published online on: 01 July 1999

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Article

The rising incidence of breast cancer in women and prostate cancer in men. Dietary influences: a possible preventive role for nature's sex hormone modifiers - the phytoestrogens (review).

F O Stephens
Pages: 865-935
Published online on: 01 July 1999

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Article

Metallothionein expression and zinc levels in invasive ductal breast carcinoma.

R Jin, B Bay, P Tan, B K Tan
Pages: 871-876
Published online on: 01 July 1999

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Article

Analysis of Ki-67, p53 and Bcl-2 expression in the dysplasia-carcinoma sequence of Barrett's esophagus.

N Rioux-Leclercq, B Turlin, F Sutherland, N Heresbach, B Launois, J P Campion, M P Ramee
Pages: 877-959
Published online on: 01 July 1999

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Article

Tissue-specific expression of the p53 tumor-suppressor gene in the intestine of transgenic mice exposed to DMH and p53 antibodies.

Y Tendler, P Guervich, B Sandler, E Diamond, S Lischinsky, T Shkolnik, O Zinder, I Zusman
Pages: 883-889
Published online on: 01 July 1999

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Article

Individual variations of total and percent free serum prostatic specific antigen: could they change the indication of prostatic biopsy?

J Morote, G Encabo, M Lopez, I M De Torres
Pages: 887-977
Published online on: 01 July 1999

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Article

Clinical relevance of molecular markers in neuroblastoma: results from a single institution.

S Gallego, A Parareda, F Munell, J Sanchez de Toledo, J Reventos
Pages: 891-897
Published online on: 01 July 1999

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Article

Transplacental tumor-preventive effects of polyclonal antibodies generated against the soluble 53 kDa antigen on mammary tumorigenesis in offspring.

B Sandler, P Smirnoff, P Gurevich, I Zusman
Pages: 897-1797
Published online on: 01 July 1999

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Article

Microsatellite alterations in superficial and locally advanced transitional cell carcinoma of the bladder.

I Sardi, R Bartoletti, I Occhini, M Piazzini, F Travaglini, R Guazzelli, E Montali
Pages: 901-906
Published online on: 01 July 1999

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Article

Soluble factors from the target organ enhance tumor cell angiogenesis: role of laminin SIKVAV sequence.

L E Davel, L I Puricelli, M Del Carmen C Vidal, M S De Lorenzo, E Sacerdote de Lustig, E D Bal de Kier Joffe
Pages: 907-918
Published online on: 01 July 1999

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Article

Adriamycin-ifosfamide induction chemotherapy for extremity soft tissue sarcoma: comparison of two non-randomized protocols.

O Merimsky, I Meller, J Issakov, Y Kollender, D Oron, G Flusser, M Gutman, D Lev-Chelouche, M Inbar
Pages: 913-933
Published online on: 01 July 1999

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Article

Loss of DNA-mismatch repair gene expression in oral melanomas.

M Korabiowska, U Brinck, I Ruschenburg, J F Honig, J Stachura, M Droese
Pages: 921-924
Published online on: 01 July 1999

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Article

Epigenetic events during the process of cell transformation induced by carcinogens (review).

G Nguyen-Ba, P Vasseur
Pages: 925-957
Published online on: 01 July 1999

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Retraction Open Access

[Retracted] Platelet‑derived growth factor BB mediates the glioma‑induced migration of bone marrow‑derived mesenchymal stem cells by promoting the expression of vascular cell adhesion molecule‑1 through the PI3K, P38 MAPK and NF‑κB pathways

Yi Hu, Peng Cheng, Jiang-Chun Ma, Yi-Xue Xue, Yun-Hui Liu
Article Number: 32
Published online on: 08 December 2025

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Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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