Journal Articles

Open Access

Biological functions and role of CCN1/Cyr61 in embryogenesis and tumorigenesis in the female reproductive system (Review)

Rui Yang, Ying Chen, Daozhen Chen

Pages: 3-10 Published online on: 26 October 2017
Open Access

Mycoleptodonoides aitchisonii suppresses asthma via Th2 and Th1 cell regulation in an ovalbumin‑induced asthma mouse model

Soon‑Young Lee, Chun‑Sik Bae, Ji‑Hye Seo, Seung Sik Cho, Min‑Suk Bae, Deuk‑Sil Oh, Dae‑Hun Park

Pages: 11-20 Published online on: 26 October 2017
Open Access

Vitamin E (α‑tocopherol) ameliorates aristolochic acid‑induced renal tubular epithelial cell death by attenuating oxidative stress and caspase‑3 activation

Tsai‑Kun Wu, Ying‑Ru Pan, Hsueh‑Fang Wang, Chyou‑Wei Wei, Yung‑Luen Yu

Pages: 31-36 Published online on: 27 October 2017
Open Access

Genetic characteristics of polycistronic system‑mediated randomly‑inserted multi‑transgenes in miniature pigs and mice

Siyuan Kong, Li Li, Wenjuan Zhu, Leilei Xin, Jinxue Ruan, Yubo Zhang, Shulin Yang, Kui Li

Pages: 37-50 Published online on: 20 October 2017
Open Access

Salidroside could enhance the cytotoxic effect of L‑OHP on colorectal cancer cells

Xiaoming Shi, Wei Zhao, Yongbin Yang, Shengchun Wu, Bonan Lv

Pages: 51-58 Published online on: 20 October 2017
Open Access

Messenger RNA sequencing reveals similar mechanisms between neonatal and acute respiratory distress syndrome

Hua Mei, Yuheng Zhang, Chunzhi Liu, Yayu Zhang, Chunli Liu, Dan Song, Chun Xin, Jing Wang, Jonathan Josephs‑Spaulding, Yan Zhu, Feng Tang

Pages: 59-70 Published online on: 26 October 2017
Open Access

Human umbilical cord mesenchymal stem cells alleviate interstitial fibrosis and cardiac dysfunction in a dilated cardiomyopathy rat model by inhibiting TNF‑α and TGF‑β1/ERK1/2 signaling pathways

Changyi Zhang, Guichi Zhou, Yezeng Chen, Sizheng Liu, Fen Chen, Lichun Xie, Wei Wang, Yonggang Zhang, Tianyou Wang, Xiulan Lai, Lian Ma

Pages: 71-78 Published online on: 26 October 2017
Open Access

Antiangiogenic effects of recombinant human endostatin in lung cancers

Lang He, Chaofen Zhao, Yunxiang Li, Guocheng Du, Kang Liu, Dandan Cui, Lina Tang, Xun Wu, Shimin Wen, Hong Chen

Pages: 79-86 Published online on: 24 October 2017
Open Access

Cornin protects SH‑SY5Y cells against oxygen and glucose deprivation‑induced autophagy through the PI3K/Akt/mTOR pathway

Changling Ding, Jie Zhang, Baoyuan Li, Zhaoxing Ding, Wenna Cheng, Fei Gao, Ye Zhang, Yangyang Xu, Shuping Zhang

Pages: 87-92 Published online on: 25 October 2017
Open Access

Quantitative proteomic study of the plasma reveals acute phase response and LXR/RXR and FXR/RXR activation in the chronic unpredictable mild stress mouse model of depression

Chuangchuang Yang, Chanjuan Zhou, Jie Li, Zhi Chen, Haiyang Shi, Wensong Yang, Yinhua Qin, Lin Lü, Libo Zhao, Liang Fang, Haiyang Wang, Zicheng Hu, Peng Xie

Pages: 93-102 Published online on: 20 October 2017
Open Access

Curcumin alleviates liver oxidative stress in type 1 diabetic rats

Zhenglu Xie, Binbin Wu, Guozhi Shen, Xiaqing Li, Qianying Wu

Pages: 103-108 Published online on: 26 October 2017
Open Access

Identification of biomarkers for childhood obesity based on expressional correlation and functional similarity

Zheng‑Lun Zhu, Qiu‑Meng Yang, Chen Li, Jun Chen, Min Xiang, Ming‑Min Chen, Min Yan, Zheng‑Gang Zhu

Pages: 109-116 Published online on: 27 October 2017
Open Access

DNA methyltransferase 3a modulates chemosensitivity to gemcitabine and oxaliplatin via CHK1 and AKT in p53‑deficient pancreatic cancer cells

Wei Jing, Na Song, Yunpeng Liu, Xiujuan Qu, Kezuo Hou, Xianghong Yang, Xiaofang Che

Pages: 117-124 Published online on: 27 October 2017
Open Access

XIAP underlies apoptosis resistance of renal cell carcinoma cells

Wen Zheng Yang, Haijiang Zhou, Yong Yan

Pages: 125-130 Published online on: 27 October 2017
Open Access

Overexpression of miR‑185 inhibits autophagy and apoptosis of dopaminergic neurons by regulating the AMPK/mTOR signaling pathway in Parkinson's disease

Zhi Wen, Jie Zhang, Peng Tang, Ning Tu, Ke Wang, Guangyao Wu

Pages: 131-137 Published online on: 26 October 2017
Open Access

Ganoderma lucidum polysaccharide inhibits prostate cancer cell migration via the protein arginine methyltransferase 6 signaling pathway

Xiaohui Zhao, Dayu Zhou, Yunen Liu, Chun Li, Xiaoguang Zhao, Ying Li, Wei Li

Pages: 147-157 Published online on: 26 October 2017
Open Access

Effect of β‑ecdysterone on glucocorticoid‑induced apoptosis and autophagy in osteoblasts

Yang‑Hua Tang, Zhen‑Shuang Yue, Guo‑Song Li, Lin‑Ru Zeng, Da‑Wei Xin, Zhong‑Qing Hu, Can‑Da Xu

Pages: 158-164 Published online on: 20 October 2017
Open Access

Gene expression profiles and protein‑protein interaction networks during tongue carcinogenesis in the tumor microenvironment

Wei Sun, Zeting Qiu, Wenqi Huang, Minghui Cao

Pages: 165-171 Published online on: 20 October 2017
Open Access

Prenatal diagnosis and genetic counseling for Waardenburg syndrome type I and II in Chinese families

Li Wang, Litao Qin, Tao Li, Hongjian Liu, Lingcao Ma, Wan Li, Dong Wu, Hongdan Wang, Qiannan Guo, Liangjie Guo, Shixiu Liao

Pages: 172-178 Published online on: 25 October 2017
Open Access

n-butanol extract from Folium isatidis inhibits the lipopolysaccharide-induced downregulation of CXCR1 and CXCR2 on human neutrophils

Beibei Wu, Liyin Wang, Lili Jiang, Lili Dong, Fengli Xu, Yili Lu, Jiahui Jin, Zhanyue Wang, Guang Liang, Xiaoou Shan

Pages: 179-185 Published online on: 25 October 2017
Open Access

Predicting pathogenic genes for primary myelofibrosis based on a system‑network approach

Shu‑Cai Xu, Peng Ning

Pages: 186-192 Published online on: 20 October 2017
Open Access

Abnormal DNA methylation may contribute to the progression of osteosarcoma

Xiao‑Gang Chen, Liang Ma, Jia‑Xin Xu

Pages: 193-199 Published online on: 25 October 2017
Open Access

Wnt/β‑catenin pathway activation and silencing of the APC gene in HPV‑positive human cervical cancer‑derived cells

Erick Ayala‑Calvillo, Luis Humberto Mojica‑Vázquez, Alejandro García‑Carrancá, Leticia González‑Maya

Pages: 200-208 Published online on: 20 October 2017
Open Access

Adiponectin and its receptors are involved in hypertensive vascular injury

Ruimin Guo, Min Han, Juan Song, Jun Liu, Yanni Sun

Pages: 209-215 Published online on: 25 October 2017
Open Access

Construction of a prognostic prediction system for pancreatic ductal adenocarcinoma to investigate the key prognostic genes

Bingli Zheng, Jie Peng, Ablikim Mollayup, Ahmat Bakri, Lei Guo, Jianjiang Zheng, Hui Xu

Pages: 216-224 Published online on: 20 October 2017
Open Access

Genetic variations in Bestrophin‑1 and associated clinical findings in two Chinese patients with juvenile‑onset and adult‑onset best vitelliform macular dystrophy

Ying Lin, Tao Li, Chenghong Ma, Hongbin Gao, Chuan Chen, Yi Zhu, Bingqian Liu, Yu Lian, Ying Huang, Haichun Li, Qingxiu Wu, Xiaoling Liang, Chenjin Jin, Xinhua Huang, Jianhua Ye, Lin Lu

Pages: 225-233 Published online on: 27 October 2017
Open Access

Activation of corticotropin-releasing factor receptor 1 aggravates dextran sodium sulphate-induced colitis in mice by promoting M1 macrophage polarization

Hong Chen, Haitao Shi, Yaping Liu, Xiaoyang Ren, Shuixiang He, Xinming Chang, Yan Yin

Pages: 234-242 Published online on: 26 October 2017
Open Access

TALENs-mediated homozygous CCR5Δ32 mutations endow CD4+ U87 cells with resistance against HIV‑1 infection

Ai Qing Yu, Yan Ding, Zhi Yong Lu, Yan Zhe Hao, Zhi Ping Teng, Shi Rong Yan, Dong Sheng Li, Yi Zeng

Pages: 243-249 Published online on: 26 October 2017
Open Access

Three-dimensional hydrogel is suitable for targeted investigation of amoeboid migration of glioma cells

Yubao Huang, Luqing Tong, Li Yi, Chen Zhang, Long Hai, Tao Li, Shengping Yu, Wei Wang, Zhennan Tao, Haiwen Ma, Peidong Liu, Yang Xie, Xuejun Yang

Pages: 250-256 Published online on: 26 October 2017
Open Access

Salidroside slows the progression of EA.hy926 cell senescence by regulating the cell cycle in an atherosclerosis model

Lin Sun, Fangfang Dou, Jiulin Chen, Huiying Chi, Sanli Xing, Te Liu, Shenwei Sun, Chuan Chen

Pages: 257-263 Published online on: 25 October 2017
Open Access

Erythropoietin signaling increases neurogenesis and oligodendrogenesis of endogenous neural stem cells following spinal cord injury both in vivo and in vitro

Hui Zhang, Xiao Fang, Dake Huang, Qingli Luo, Meijuan Zheng, Kangkang Wang, Le Cao, Zongsheng Yin

Pages: 264-272 Published online on: 25 October 2017
Open Access

Transcriptome sequencing revealed candidate genes relevant to mesenchymal stem cells' role in aortic dissection patients

Junlin Yang, Sili Zou, Mingfang Liao, Lefeng Qu

Pages: 273-283 Published online on: 20 October 2017
Open Access

Aconitine induces apoptosis in H9c2 cardiac cells via mitochondria‑mediated pathway

Xiangting Gao, Xincai Zhang, Jun Hu, Xuehua Xu, Yuanyi Zuo, Yun Wang, Jingfeng Ding, Hongfei Xu, Shaohua Zhu

Pages: 284-292 Published online on: 26 October 2017
Open Access

Effects of long‑term scopolamine treatment on cognitive deficits and calcium binding proteins immunoreactivities in the mouse hippocampus

Ji Hyeon Ahn, Bai Hui Chen, Bing Chun Yan, Joon Ha Park, Il Jun Kang, Tae‑Kyeong Lee, Jeong Hwi Cho, Bich‑Na Shin, Jae‑Chul Lee, Yong Hwan Jeon, Seongkweon Hong, Young Joo Lee, Soo Young Choi, Moo‑Ho Won

Pages: 293-299 Published online on: 27 October 2017

Genetically engineered recombinant adenovirus expressing interleukin‑2 for hepatocellular carcinoma therapy

Yunpeng Sun, Huanhuan Wu, Gang Chen, Xiaming Huang, Yunfeng Shan, Hongqi Shi, Qiyu Zhang, Yihu Zheng

Pages: 300-306 Published online on: 27 October 2017

Multi‑target inhibition by four tandem shRNAs embedded in homo‑ or hetero‑miRNA backbones

Xiao Du, Yanhui Cai, Wenjin Xi, Rui Zhang, Lintao Jia, Angang Yang, Jing Zhao, Bo Yan

Pages: 307-314 Published online on: 20 October 2017

Recombinant truncated TGF‑β receptor II attenuates carbon tetrachloride‑induced epithelial‑mesenchymal transition and liver fibrosis in rats

Luxin Li, Hongzhi Li, Zhen Zhang, Junya Zheng, Yongping Shi, Jieting Liu, Yanan Cao, Xiaohuan Yuan, Yanhui Chu

Pages: 315-321 Published online on: 20 October 2017

Role of the microRNA 181 family in glioma development

Liu Yang, Yueyun Ma, Yijuan Xin, Ruobin Han, Rui Li , Xiaoke Hao

Pages: 322-329 Published online on: 26 October 2017

Overexpression of miR‑21 promotes neural stem cell proliferation and neural differentiation via the Wnt/β‑catenin signaling pathway in vitro

Wei‑Min Zhang, Zhi‑Ren Zhang, Xi‑Tao Yang, Yong‑Gang Zhang, Yan‑Sheng Gao

Pages: 330-335 Published online on: 24 October 2017

The HMGB1‑IL‑17A axis contributes to hypoxia/reoxygenation injury via regulation of cardiomyocyte apoptosis and autophagy

Xiaorong Hu, Kai Zhang, Zhiqiang Chen, Hong Jiang, Weipan Xu

Pages: 336-341 Published online on: 20 October 2017

SIRT5 promotes cell proliferation and invasion in hepatocellular carcinoma by targeting E2F1

Liang Chang, Liang Xi, Yubin Liu, Rui Liu, Zhongshi Wu, Zhixiang Jian

Pages: 342-349 Published online on: 25 October 2017

Studying hepcidin and related pathways in osteoblasts using a mouse model with insulin receptor substrate 1‑loss of function

Jia Liu, Ling Qian, Linna Guo, Yunzhi Feng

Pages: 350-357 Published online on: 25 October 2017

Hedyotis diffusa Willd inhibits proliferation and induces apoptosis of 5‑FU resistant colorectal cancer cells by regulating the PI3K/AKT signaling pathway

Qiongyu Li, Zijun Lai, Zhaokun Yan, Jun Peng, Yiyi Jin, Lihui Wei, Jiumao Lin

Pages: 358-365 Published online on: 26 October 2017

Torin2 enhances the radiosensitivity of MCF‑7 breast cancer cells by downregulating the mTOR signaling pathway and ATM phosphorylation

Jia Luo, Guocheng Pi, He Xiao, Yunfei Ye, Qing Li, Lianhua Zhao, Huan Huang, Hong Luo, Qin Zhang, Dong Wang, Ge Wang

Pages: 366-373 Published online on: 20 October 2017

Melatonin ameliorates myocardial apoptosis by suppressing endoplasmic reticulum stress in rats with long‑term diabetic cardiomyopathy

Fang‑Yuan Xiong, Song‑Tao Tang, Huan Su, Hai‑Qin Tang, Pin Jiang, Qing Zhou, Yuan Wang, Hua‑Qing Zhu

Pages: 374-381 Published online on: 20 October 2017

Genetic diagnosis and pathogenic analysis of an atypical hereditary spherocytosis combined with UGT1A1 partial deficiency: A case report

Yan Yi, Xiqiang Dang, Yonggui Li, Chenyu Zhao, Haiyan Tang, Xiaoliu Shi

Pages: 382-387 Published online on: 25 October 2017

The rational search for PDE10A inhibitors from Sophora flavescens roots using pharmacophore‑ and docking‑based virtual screening

Han‑Tian Fan, Jun‑Fang Guo, Yu‑Xin Zhang, Yu‑Xi Gu, Zhong‑Qi Ning, Yan‑Jiang Qiao, Xing Wang

Pages: 388-393 Published online on: 25 October 2017

Expression, purification and epitope analysis of Pla a 2 allergen from Platanus acerifolia pollen

De‑Wang Wang, Wei‑Wei Ni, Yan‑Jun Zhou, Wen Huang, Meng‑Da Cao, Ling Meng, Ji‑Fu Wei

Pages: 394-399 Published online on: 26 October 2017

Coenzyme Q10 promotes osteoblast proliferation and differentiation and protects against ovariectomy-induced osteoporosis

Delu Zheng, Chenli Cui, Meng Yu, Xiang Li, Lu Wang, Xinyan Chen, Yichen Lin

Pages: 400-407 Published online on: 26 October 2017

Evaluation of the accuracy and sensitivity of high‑throughput sequencing technology using known microbiota

Fanjing Meng, Tingtao Chen, Xin Wang, Xiaolei Wang, Hua Wei, Puyuan Tian, Huan Wang, Xiaoxiao Zhao, Liang Shen, Hongbo Xin

Pages: 408-413 Published online on: 20 October 2017

Effects of hypoxia‑inducible factor‑1α on endometrial receptivity of women with polycystic ovary syndrome

Dongmei Zhao, Qinglan Qu, Huangguan Dai, Yueyang Liu, Lei Jiang, Xin Huang, Cuifang Hao

Pages: 414-421 Published online on: 26 October 2017

Effects of Dermatopontin gene silencing on apoptosis and proliferation of osteosarcoma MG‑63 cells

Li‑Cheng Xi, Yun‑Xi Ji, Dong Yin, Zi‑Xing Zhao, Si‑Cheng Huang, Shao‑Lin Yu, Bo‑Yu Liu, Hong‑Yu Li

Pages: 422-427 Published online on: 25 October 2017

Adiponectin promotes preadipocyte differentiation via the PPARγ pathway

Wenkai Yang, Chunli Yang, Jun Luo, Yutao Wei, Wenying Wang, Yingmei Zhong

Pages: 428-435 Published online on: 26 October 2017

Preparation of chitosan‑silicon dioxide/BCSG1‑siRNA nanoparticles to enhance therapeutic efficacy in breast cancer cells

Lan Cui, Ruifeng Zheng, Wentao Liu, Peihong Shen, Youcai Tang, Junbo Luo, Wei Zhang, Guocong Jia, Yongfeng Wang, Shuaihua Zhao, Qiaoting Xie, Yanwei Li

Pages: 436-441 Published online on: 26 October 2017

miR‑126 is essential for endothelial phenotype expression during endothelial differentiation in adipose‑derived stem cells

Han Xie, Fang Wang, Xiao Chen, Hao Ying

Pages: 442-446 Published online on: 27 October 2017

Apelin‑13 promotes cell proliferation in the H9c2 cardiomyoblast cell line by triggering extracellular signal‑regulated kinase 1/2 and protein kinase B phosphorylation

Luhua Yin, Pu Zhang, Chao Li, Jiafeng Si, Yongmei Wang, Xuemei Zhang, Deqing Zhang, Huanyi Zhang, Cong Lin

Pages: 447-451 Published online on: 27 October 2017

In vivo monitoring of magnetically labeled mesenchymal stem cells homing to rabbit hepatic VX2 tumors using magnetic resonance imaging

Yong Qin, Lisha Zhuo, Jinhua Cai, Xiaoya He, Bo Liu, Chuan Feng, Lin Zhang

Pages: 452-458 Published online on: 26 October 2017

Rottlerin inhibits cell growth, induces apoptosis and cell cycle arrest, and inhibits cell invasion in human hepatocellular carcinoma

Jichan Shi, Hongye Ning, Guiqing He, Yitong Huang, Zhengxing Wu, Lingling Jin, Xiangao Jiang

Pages: 459-464 Published online on: 27 October 2017
Open Access

Overexpression of CCDC34 in colorectal cancer and its involvement in tumor growth, apoptosis and invasion

Wei Geng, Wei Liang, Yanan Fan, Zhibin Ye, Lixiao Zhang

Pages: 465-473 Published online on: 24 October 2017

GMZ-1 is a podophyllotoxin derivative that suppresses growth and induces apoptosis in adriamycin-resistant K562/A02 cells through modulation of MDR1 expression

Bo Cao, Shuwang Yang, Wuwei Li, Hong Chen, Yaze Chen, Yongfeng Liu, Bin Liu

Pages: 474-478 Published online on: 25 October 2017

Aspirin ameliorates cerebral infarction through regulation of TLR4/NF‑κB‑mediated endoplasmic reticulum stress in mouse model

Xin Wang, Bin Shen, Dezhou Sun, Xiangyu Cui

Pages: 479-487 Published online on: 25 October 2017

Isolariciresinol-9'-O-α-L-arabinofuranoside protects against hydrogen peroxide‑induced apoptosis of human umbilical vein endothelial cells via a PI3K/Akt/Bad‑dependent pathway

Li‑Tao Liu, Lei Liang, Wei Wang, Cui‑Qi Yan, Jing Zhang, Yun‑Chuan Xiao, Liang Ye, Man‑Xi Zhao, Quan‑Shu Huang, Jun‑Jie Bian, Zhang‑Fei Shi, Xiao Ke, Zhi‑Rong Zhang

Pages: 488-494 Published online on: 25 October 2017

Protective effect of diltiazem on myocardial ischemic rats induced by isoproterenol

Yuejiao Wei, Tianyu Meng, Chaofeng Sun

Pages: 495-501 Published online on: 26 October 2017

Resveratrol-mediated apoptosis in renal cell carcinoma via the p53/AMP‑activated protein kinase/mammalian target of rapamycin autophagy signaling pathway

Qingjun Liu, Qiang Fang, Shiqi Ji, Zhixing Han, Wenlong Cheng, Haijian Zhang

Pages: 502-508 Published online on: 25 October 2017

Role of transcription factor FOXA1 in non‑small cell lung cancer

Jia Li, Shirong Zhang, Lucheng Zhu, Shenglin Ma

Pages: 509-521 Published online on: 26 October 2017

Anticancer effect of quinacrine on diffuse large B‑cell lymphoma via inhibition of MSI2‑NUMB signaling pathway

Shujun Yang, Lixia Sheng, Kaihong Xu, Yi Wang, Huiling Zhu, Ping Zhang, Qitian Mu, Guifang Ouyang

Pages: 522-530 Published online on: 26 October 2017

Metabolic alterations in the rat cerebellum following acute middle cerebral artery occlusion, as determined by 1H NMR spectroscopy

Zi‑Long Hu, Huan‑Huan Xia, Yun‑Jun Yang, Hong Zheng, Liang‑Cai Zhao, Yong‑Chun Chen, Qi‑Chuan Zhuge, Neng‑Zhi Xia, Hong‑Chang Gao, Wei‑Jian Chen

Pages: 531-541 Published online on: 27 October 2017

GOLPH3 expression promotes the resistance of HT29 cells to 5‑fluorouracil by activating multiple signaling pathways

Ming‑Zhen Wang, Cheng‑Zhi Qiu, Wai‑Shi Yu, Yan‑Ta Guo, Chun‑Xiao Wang, Zhi‑Xiong Chen

Pages: 542-548 Published online on: 25 October 2017

UNBS5162 inhibits the proliferation of esophageal cancer squamous cells via the PI3K/AKT signaling pathway

Dan He, Suolin Zhang

Pages: 549-555 Published online on: 26 October 2017

Schisandrin B protects against myocardial ischemia/reperfusion injury via the PI3K/Akt pathway in rats

Xuyong Zhao, Yijia Xiang, Changhong Cai, Aiming Zhou, Ning Zhu, Chunlai Zeng

Pages: 556-561 Published online on: 27 October 2017

MicroRNA‑27a promotes tumorigenesis via targeting AKT in triple negative breast cancer

Jing Wu, Zhihui Sun, Huijie Sun, Yanhua Li

Pages: 562-570 Published online on: 26 October 2017

PTEN promotes apoptosis of H2O2‑injured rat nasal epithelial cells through PI3K/Akt and other pathways

Minghui Jia, Xiaoyun Chen, Jili Liu, Jun Chen

Pages: 571-579 Published online on: 26 October 2017

MicroRNA‑512‑3p is upregulated, and promotes proliferation and cell cycle progression, in prostate cancer cells

Zhigang Rao, Ziqi He, Yi He, Zonghua Guo, Dongbo Kong, Jufang Liu

Pages: 586-593 Published online on: 20 October 2017

Histone deacetylase inhibition of cardiac autophagy in rats on a high‑fat diet with low‑dose streptozotocin-induced type 2 diabetes mellitus

Ting‑I Lee, Kuan‑Jen Bai, Yao‑Chang Chen, Ting‑Wei Lee, Cheng‑Chih Chung, Wen‑Chih Tsai, Shin‑Yi Tsao, Yu‑Hsun Kao

Pages: 594-601 Published online on: 26 October 2017

MicroRNA-197 inhibits gastric cancer progression by directly targeting metadherin

Zhiwei Liao, Yue Li, Yuanhang Zhou, Qi Huang, Jian Dong

Pages: 602-611 Published online on: 26 October 2017

MicroRNA‑20a promotes inflammation via the nuclear factor‑κB signaling pathway in pediatric pneumonia

Zhihong Liu, Haiying Yu, Qiuye Guo

Pages: 612-617 Published online on: 26 October 2017

miR-17-3P regulates the proliferation and survival of colon cancer cells by targeting Par4

Debao Lu, Liang Tang, Yan Zhuang, Peng Zhao

Pages: 618-623 Published online on: 25 October 2017

miR-93‑mediated collagen expression in stress urinary incontinence via calpain-2

Shi‑Jie Yang, Jian Wang, Jie Xu, Yun Bai, Zhao‑Jun Guo

Pages: 624-629 Published online on: 26 October 2017

MAPKs and NF‑κB pathway inhibitory effect of bisdemethoxycurcumin on phorbol‑12‑myristate‑13‑acetate and A23187‑induced inflammation in human mast cells

Ryong Kong, Ok‑Hwa Kang, Yun‑Soo Seo, Tian Zhou, Sang‑A Kim, Dong‑Won Shin, Dong‑Yeul Kwon

Pages: 630-635 Published online on: 20 October 2017

Astragaloside IV attenuates penicillin-induced epilepsy via inhibiting activation of the MAPK signaling pathway

Xingming Zhu, Yang Chen, Yuping Du, Qi Wan, Yan Xu, Jiayu Wu

Pages: 643-647 Published online on: 26 October 2017

Isorhamnetin prevents H2O2‑induced oxidative stress in human retinal pigment epithelial cells

Jing Wang, Hui‑Min Gong, Hui‑Hui Zou, Ling Liang, Xin‑Yi Wu

Pages: 648-652 Published online on: 27 October 2017

Application of oligonucleotides to construct a conditional targeting vector for porcine IκBα

Hegang Li, Xiaona Song, Feng Yang, Hanxun Bao, Xiaolong Lu, Flor M. Perez‑Campo, Jinshan Zhao

Pages: 653-659 Published online on: 27 October 2017

Galangin increases ERK1/2 phosphorylation to decrease ADAM9 expression and prevents invasion in A172 glioma cells

Deqiang Lei, Fangcheng Zhang, Dongxiao Yao, Nanxiang Xiong, Xiaobing Jiang, Hongyang Zhao

Pages: 667-673 Published online on: 27 October 2017

Dysifragilone A inhibits LPS‑induced RAW264.7 macrophage activation by blocking the p38 MAPK signaling pathway

Huixiang Li, Qian Zhang, Xin Jin, Xiaowen Zou, Yuexuan Wang, Dexiang Hao, Fenghua Fu, Weihua Jiao, Cuixia Zhang, Houwen Lin, Keiichi Matsuzaki, Feng Zhao

Pages: 674-682 Published online on: 26 October 2017

Clinical application of a novel diagnostic scheme including pancreatic β‑cell dysfunction for traumatic multiple organ dysfunction syndrome

Zhan‑Ke Wang, Rong‑Jian Chen, Shi‑Liang Wang, Guang‑Wei Li, Zhong‑Zhen Zhu, Qiang Huang, Zi‑Li Chen, Fan‑Chang Chen, Lei Deng, Xiao‑Peng Lan, Tian Hu

Pages: 683-693 Published online on: 26 October 2017

TGF‑β signaling: A complex role in tumorigenesis (Review)

Shuang Liu, Shuang Chen, Jun Zeng

Pages: 699-704 Published online on: 06 November 2017
Open Access

Characterization of cholesterol metabolism in Sertoli cells and spermatogenesis (Review)

Jin‑Feng Shi, Yu‑Kun Li, Kun Ren, Yuan‑Jie Xie, Wei‑Dong Yin, Zhong‑Cheng Mo

Pages: 705-713 Published online on: 07 November 2017

Advances in the T7 phage display system (Review)

Xiangying Deng, Li Wang, Xiaolong You, Pei Dai, Yanhua Zeng

Pages: 714-720 Published online on: 07 November 2017
Open Access

Two‑component histidine kinase DRK1 is required for pathogenesis in Sporothrix schenckii

Zhenying Zhang, Binbin Hou, Yong Zhuo Wu, Ying Wang, Xiaoming Liu, Shixin Han

Pages: 721-728 Published online on: 07 November 2017
Open Access

Upregulation of connexin43 by glucose deprivation in H9c2 cells via the extracellular signal‑regulated kinase/mitogen‑activated protein kinase signaling pathway

Guangyu Wang, Yaguang Bi, Xiangdong Liu, Meng Wei, Qingyong Zhang

Pages: 729-734 Published online on: 06 November 2017
Open Access

Differential expression of cyclin D1, Ki‑67, pRb, and p53 in psoriatic skin lesions and normal skin

Sung Ae Kim, Young Wook Ryu, Jun Il Kwon, Mi Sun Choe, Jin Woong Jung, Jae We Cho

Pages: 735-742 Published online on: 08 November 2017
Open Access

Hepatocellular toxicity of oxalicumone A via oxidative stress injury and mitochondrial dysfunction in healthy human liver cells

Si Shi, Limei Yao, Kunbin Guo, Xiangyu Wang, Qi Wang, Weirong Li

Pages: 743-752 Published online on: 06 November 2017
Open Access

Cytochrome P450 1A1 and 1B1 promoter CpG island methylation regulates rat liver injury induced by isoniazid

Yanhui Li, Yuhong Li, Guoying Zheng, Lingyan Zhu, Jishun Wang, Shasha Mu, Qi Ren, Fumin Feng

Pages: 753-762 Published online on: 31 October 2017
Open Access

Effects of Shield1 on the viral replication of varicella‑zoster virus containing FKBP‑tagged ORF4 and 48

Shuying Li, Zhanjun Liu, Ji Li, Aihua Liu, Lihua Zhu, Kui Yu, Ke Zhang

Pages: 763-770 Published online on: 06 November 2017
Open Access

Oligodendrocyte precursor cell transplantation promotes functional recovery following contusive spinal cord injury in rats and is associated with altered microRNA expression

Jin Yang, Liu‑Lin Xiong, You‑Cui Wang, Xiang He, Ling Jiang, Song‑Jun Fu, Xue‑Fei Han, Jia Liu, Ting‑Hua Wang

Pages: 771-782 Published online on: 03 November 2017
Open Access

MicroRNA‑103 regulates tumorigenesis in colorectal cancer by targeting ZO‑1

Jin Ke, Weiwei Shao, Yasu Jiang, Junfei Xu, Feng Li, Jun Qin

Pages: 783-788 Published online on: 07 November 2017
Open Access

Protective effects of silymarin on triptolide-induced acute hepatotoxicity in rats

Lan Wang, Qiong-Hui Huang, Yong-Xian Li, Yan-Feng Huang, Jian-Hui Xie, Lie-Qiang Xu, Yao-Xing Dou, Zi-Ren Su, Hui-Fang Zeng, Jian-Nan Chen

Pages: 789-800 Published online on: 03 November 2017
Open Access

Effects of Lycium barbarum (goji berry) on dry eye disease in rats

Kaung‑Jen Chien, Chi‑Ting Horng, Yu‑Syuan Huang, Yi‑Hsien Hsieh, Chau‑Jong Wang, Jai‑Sing Yang, Chi‑Cheng Lu, Fu‑An Chen

Pages: 809-818 Published online on: 03 November 2017
Open Access

Curcumin suppresses Notch‑1 signaling: Improvements in fatty liver and insulin resistance in rats

Neng‑Jiang Zhao, Ming‑Juan Liao, Jing‑Jing Wu, Ke‑Xin Chu

Pages: 819-826 Published online on: 06 November 2017
Open Access

Effect of Linguizhugan decoction on neuroinflammation and expression disorder of the amyloid β‑related transporters RAGE and LRP‑1 in a rat model of Alzheimer's disease

Qianfeng Hu, Beibei Yu, Qinlei Chen, Yi Wang, Yun Ling, Songxian Sun, Yinlong Shi, Chunxiang Zhou

Pages: 827-834 Published online on: 06 November 2017
Open Access

Downregulation of TRIM28 inhibits growth and increases apoptosis of nude mice with non‑small cell lung cancer xenografts

Lei Liu, Lei Zhang, Jianping Wang, Xuerong Zhao, Qian Xu, Yanjie Lu, Yanzhen Zuo, Long Chen, Jia Du, Yali Lian, Qin Zhang

Pages: 835-842 Published online on: 03 November 2017
Open Access

D‑Tagatose inhibits the growth and biofilm formation of Streptococcus mutans

Khaleque Hasibul, Haruyuki Nakayama‑Imaohji, Masahito Hashimoto, Hisashi Yamasaki, Takaaki Ogawa, Junpei Waki, Ayano Tada, Saori Yoneda, Masaaki Tokuda, Minoru Miyake, Tomomi Kuwahara

Pages: 843-851 Published online on: 08 November 2017
Open Access

Serum microRNA expression profiling in patients with multiple system atrophy

Kodai Kume, Hisakazu Iwama, Kazushi Deguchi, Kazuyo Ikeda, Tadayuki Takata, Yohei Kokudo, Masaki Kamada, Keiko Fujikawa, Kayo Hirose, Hisashi Masugata, Tetsuo Touge, Tsutomu Masaki

Pages: 852-860 Published online on: 07 November 2017
Open Access

A novel method to isolate mesenchymal stem cells from mouse umbilical cord

Bin Zhang, Jie Zhang, Hui Shi, Fei Mao, Juanjuan Wang, Yongmin Yan, Xu Zhang, Hui Qian, Wenrong Xu

Pages: 861-869 Published online on: 03 November 2017
Open Access

Application of F0F1‑ATPase immuno‑biosensors for detecting Escherichia coli O157:H7

Ling Wei, Bao‑Ming Li, Cheng‑Bin Wang, Zi‑Jia Kang, Jie Sun, Hui‑Juan Wu, Yong‑Zhi Lun

Pages: 870-876 Published online on: 07 November 2017
Open Access

Trichosanthes kirilowii extract enhances repair of UVB radiation‑induced DNA damage by regulating BMAL1 and miR‑142‑3p in human keratinocytes

Ji‑Hye Joo, In‑Kee Hong, Nam Kyoung Kim, Eunmi Choi

Pages: 877-883 Published online on: 31 October 2017

Effects of daphnetin combined with Bcl2‑siRNA on antiapoptotic genes in synovial fibroblasts of rats with collagen‑induced arthritis

Xiaoying Chen, Nanzhen Kuang, Xiaoping Zeng, Zhiqin Zhang, Yanyan Li, Wei Liu, Yingyuan Fu

Pages: 884-890 Published online on: 07 November 2017
Open Access

Identification of key genes, transcription factors and microRNAs involved in intracranial aneurysm

Liang Wei, Qi Wang, Yanfei Zhang, Cheng Yang, Hongxin Guan, Yiming Chen, Zhiyang Sun

Pages: 891-897 Published online on: 03 November 2017
Open Access

Roles and mechanisms of TRPC3 and the PLCγ/PKC/CPI-17 signaling pathway in regulating parturition

Jing Chen, Dongming Zheng, Hong Cui, Sishi Liu, Lijuan Zhang, Caixia Liu

Pages: 898-910 Published online on: 07 November 2017
Open Access

Effect of silencing TEM8 gene on proliferation, apoptosis, migration and invasion of XWLC‑05 lung cancer cells

Quan Gong, Chao Liu, Cunde Wang, Li Zhuang, Lijuan Zhang, Xicai Wang

Pages: 911-917 Published online on: 03 November 2017
Open Access

Resveratrol improves prostate fibrosis during progression of urinary dysfunction in chronic prostatitis by mast cell suppression

Huizhi Zeng, Yi He, Yang Yu, Jiashu Zhang, Xiaona Zeng, Fengtao Gong, Qi Liu, Bo Yang

Pages: 918-924 Published online on: 03 November 2017
Open Access

Different inhibitory effects on the proliferation and apoptosis of human and laboratory Borna disease virus‑infected human neuroblastoma SH‑SY5Y cells in vitro

Hua Huang, Hong Zhang, Dan Li, Shigang Chen, Chanjuan Zhou, Qi Li, Peng He, Liang Fang, Yong Zhang, Xiaomei Li, Jingjing Zhou, Lin Sun, Siwen Liu, Yujie Guo, Ying Huang, Peng Xie

Pages: 925-931 Published online on: 08 November 2017
Open Access

Identification of differentially expressed microRNAs in acute Kawasaki disease

Ye Chen, Yue‑Yue Ding, Yan Ren, Lei Cao, Qiu‑Qin Xu, Ling Sun, Ming‑Guo Xu, Hai‑Tao Lv

Pages: 932-938 Published online on: 08 November 2017
Open Access

Prognostic microRNAs and their potential molecular mechanism in pancreatic cancer: A study based on The Cancer Genome Atlas and bioinformatics investigation

Liang Liang, Dan‑Ming Wei, Jian‑Jun Li, Dian‑Zhong Luo, Gang Chen, Yi‑Wu Dang, Xiao‑Yong Cai

Pages: 939-951 Published online on: 03 November 2017
Open Access

TIPE2 governs macrophage polarization via negative regulation of mTORC1

Yuan Jiang, Qiang Li, Yuanyuan Zhang, Yuzhi Gao, Libing Jiang, Zhimin Chen

Pages: 952-960 Published online on: 06 November 2017
Open Access

Endothelial‑to‑mesenchymal transition in human idiopathic dilated cardiomyopathy

Yeqing Xie, Jianquan Liao, Yong Yu, Qi Guo, Yingzhen Yang, Junbo Ge, Haozhu Chen, Ruizhen Chen

Pages: 961-969 Published online on: 08 November 2017
Open Access

Polygonum multiflorm alleviates glucocorticoid‑induced osteoporosis and Wnt signaling pathway

Manru Zhou, Jingkai Wu, Yongjie Yu, Yajun Yang, Jin Li, Liao Cui, Weimin Yao, Yuyu Liu

Pages: 970-978 Published online on: 07 November 2017
Open Access

Liver dual arterial blood supply maintains liver regeneration: Analysis of signaling pathways in rats

Jian‑Liang Qiao, Juan Sun, Jun Li, Jun‑Jing Zhang, Xing‑Kai Meng

Pages: 979-987 Published online on: 03 November 2017
Open Access

Comparison of the osteogenic differentiation of orofacial bone marrow stromal cells prior to and following marsupialization in patients with odontogenic cyst

Yao Sun, Juan Zhang, Naiying Qian, Guoqi Sima, Jianming Zhang, Jiayong Zhong, Zhiqin Guo, Yawen Chen, Weijie Dong

Pages: 988-994 Published online on: 03 November 2017
Open Access

Alanine scanning mutagenesis of SP70 epitope in characterizing species‑specific antibodies induced by enterovirus 71‑based antigens

Meng Gao, Feng Zhang, Yun Zhu, Limei Gao, Yunshui Jiang, Yongneng Luo, Fangchang Zhuang, Zian Mao, Jiangsen Mao

Pages: 1006-1014 Published online on: 06 November 2017
Open Access

The shortening telomere length of T lymphocytes maybe associated with hyper‑function in servere aplastic anemia

Chaomeng Wang, Tian Zhang, Yihao Wang, Yang Li, Chunyan Liu, Hui Liu, Lijuan Li, Kai Ding, Ting Wang, Honglei Wang, Zonghong Shao, Rong Fu

Pages: 1015-1021 Published online on: 08 November 2017

Elemene inhibits osteosarcoma growth by suppressing the renin‑angiotensin system signaling pathway

Lixiang Ding, Genai Zhang, Yu Hou, Jiao Chen, Yukun Yin

Pages: 1022-1030 Published online on: 06 November 2017

HGF induces the serine‑phosphorylation and cell surface translocation of ROMK (Kir 1.1) channels in rat kidney cells

Takashi Kato, Kiyomasa Oka, Toshikazu Nakamura

Pages: 1031-1034 Published online on: 06 November 2017

HuR induces inflammatory responses in HUVECs and murine sepsis via binding to HMGB1

Jian Wang, Ling Zhao, Yong Li, Shunyi Feng, Guangxin Lv

Pages: 1049-1056 Published online on: 08 November 2017

Influence of androgen on myocardial apoptosis and expression of myocardial IR and IRS‑1 in chronic heart failure rat models

Yu Wang, Yang Hu, Zhaoping Zeng, Yinghua Li, Huipeng Su, Yiwei Li, Ruiping Wang, Mingqian Zhang, Yongli Yang, Jie Deng

Pages: 1057-1064 Published online on: 08 November 2017

Epithelial‑mesenchymal transition in colorectal carcinoma cells is mediated by DEK/IMP3

Shuping You, Yun Guan, Weihong Li

Pages: 1065-1070 Published online on: 03 November 2017

Oxymatrine induces A549 human non‑small lung cancer cell apoptosis via extrinsic and intrinsic pathways

Guang‑Zhou Zhou, Yan‑Yan Shi, Liu‑Su Cui, A‑Fang Li, Qing‑Qing Wang, Min Liu

Pages: 1071-1076 Published online on: 06 November 2017

Bryostatin 1 causes attenuation of TPA‑mediated tumor promotion in mouse skin

Ning Zeng, Yi Xu, Yiping Wu, Tang Hongbo, Min Wu

Pages: 1077-1082 Published online on: 06 November 2017
Open Access

Repeated inhalation of sevoflurane inhibits the information transmission of Purkinje cells and delays motor development via the GABAA receptor ε subunit in neonatal mice

Hong Fang, Ze‑Hua Wang, Ying‑Jiang Bu, Zhi‑Jun Yuan, Guo‑Qiang Wang, Yan Guo, Xiao‑Yun Cheng, Wen‑Jie Qiu

Pages: 1083-1092 Published online on: 03 November 2017

PirB inhibits axonal outgrowth via the PI3K/Akt/mTOR signaling pathway

Yong‑Yan Bi, Yong Quan

Pages: 1093-1098 Published online on: 31 October 2017

Effects of calcium-dependent molecular chaperones and endoplasmic reticulum in the amygdala in rats under single‑prolonged stress

Bing Xiao, Jian‑Gang Wang, Fang Han, Yu‑Xiu Shi

Pages: 1099-1104 Published online on: 06 November 2017

LncRNA PVT1 regulate expression of HIF1α via functioning as ceRNA for miR‑199a‑5p in non‑small cell lung cancer under hypoxia

Chunhong Wang, Chunfang Han, Yibo Zhang, Fengqin Liu

Pages: 1105-1110 Published online on: 03 November 2017

Downregulation of NKD1 in human osteosarcoma and its clinical significance

Xiang Chen, Ping Xu, Jianwei Zhu, Fan Liu

Pages: 1111-1117 Published online on: 06 November 2017

Lipoic acid alleviates L‑DOPA‑induced dyskinesia in 6‑OHDA parkinsonian rats via anti‑oxidative stress

Su‑Fang Zhang, Cheng‑Long Xie, Jing‑Ya Lin, Mei‑Hua Wang, Xi‑Jin Wang, Zhen‑Guo Liu

Pages: 1118-1124 Published online on: 06 November 2017

Isopsoralen regulates PPAR‑γ/WNT to inhibit oxidative stress in osteoporosis

Jian Wang, Gang Wang, Li Gong, Guanwen Sun, Bin Shi, Huhe Bao, Yan Duan

Pages: 1125-1131 Published online on: 03 November 2017

Jujuboside A attenuates norepinephrine-induced apoptosis of H9c2 cardiomyocytes by modulating MAPK and AKT signaling pathways

Chang‑Rong Wan, Dan‑Dan Han, Jian‑Qin Xu, Peng Yin, Xiao‑Long Xu, Chen Mei, Feng‑Hua Liu, Zhao‑Fei Xia

Pages: 1132-1140 Published online on: 02 November 2017

High expression of long non‑coding HOTAIR correlated with hepatocarcinogenesis and metastasis

Da‑Ni Zhong, Yi‑Huan Luo, Wei‑Jia Mo, Xin Zhang, Zhong Tan, Na Zhao, Si‑Min Pang, Gang Chen, Min‑Hua Rong, Wei Tang

Pages: 1148-1156 Published online on: 07 November 2017

Angiotensin II induces monocyte chemoattractant protein‑1 expression by increasing reactive oxygen species‑mediated activation of the nuclear factor‑κB signaling pathway in osteoblasts

Changyao Wang, Cailong Zhang, Feng Zhou, Lei Gao, Yingzhen Wang, Chunsheng Wang, Yongtao Zhang

Pages: 1166-1172 Published online on: 06 November 2017

Effect of willed movement training on neurorehabilitation after focal cerebral ischemia and on the neural plasticity-associated signaling pathway

Zhi‑Wen Zhou, Qi‑Dong Yang, Qing‑Ping Tang, Jie Yang, Rong‑Jing Guo, Wen Jiang

Pages: 1173-1181 Published online on: 03 November 2017

LncRNA PlncRNA‑1 regulates proliferation and differentiation of hair follicle stem cells through TGF‑β1‑mediated Wnt/β‑catenin signal pathway

Yuan Si, Jingzhu Bai, Jiang Wu, Qun Li, You Mo, Ruihua Fang, Wei Lai

Pages: 1191-1197 Published online on: 03 November 2017

Reactive astrocytes increase the expression of P‑gp and Mrp1 via TNF‑α and NF‑κB signaling

Xueying Wang, Shaoping Huang, Yongsheng Jiang, Yu Liu, Tingting Song, Dan Li, Lin Yang

Pages: 1198-1204 Published online on: 02 November 2017

DJ‑1 alleviates high glucose‑induced endothelial cells injury via PI3K/Akt‑eNOS signaling pathway

Hongan Tian, Shunzhen Li, Kaihu Yu

Pages: 1205-1211 Published online on: 06 November 2017

Recombinant TsP53 modulates intestinal epithelial barrier integrity via upregulation of ZO‑1 in LPS‑induced septic mice

Jia Xu, Zhihao Liu, Wei Zhan, Ren Jiang, Chunhua Yang, Hong Zhan, Yan Xiong

Pages: 1212-1218 Published online on: 03 November 2017
Open Access

Role of epigenetics in the pathogenesis of chronic rhinosinusitis with nasal polyps

Jong‑Yeup Kim, Dong‑Kyu Kim, Myeong Sang Yu, Min‑Ji Cha, Seong‑Lan Yu, Jaeku Kang

Pages: 1219-1227 Published online on: 07 November 2017

High‑cholesterol diet results in elevated amyloid‑β and oxysterols in rats

Quanri Liu, Yu An, Weiwei Ma, Lingli Feng, Chao Wang, Yanhui Lu, Rong Xiao

Pages: 1235-1240 Published online on: 07 November 2017

Association between genotype and phenotype of virulence gene in Van der Woude syndrome families

Shouxia Li, Xueqiang Zhang, Dingli Chen, Wei Zhao, Xiaofang Zhang, Jianjun Jiao, Lili Guo, Lei Yin, Xuedong Song, Chun Liang, Caixia Sun

Pages: 1241-1246 Published online on: 06 November 2017

Sparstolonin B selectively suppresses toll‑like receptor‑2 and ‑4 to alleviate neuropathic pain

Guanghui Jin, Xing Jin, Shuang Zhou

Pages: 1247-1252 Published online on: 03 November 2017

Cardioprotective effects of anisodamine against myocardial ischemia/reperfusion injury through the inhibition of oxidative stress, inflammation and apoptosis

Bao‑Ju Yao, Xiao‑Qing He, Yu‑Hui Lin, Wen‑Jun Dai

Pages: 1253-1260 Published online on: 08 November 2017

Preventive effect of hesperidin modulates inflammatory responses and antioxidant status following acute myocardial infarction through the expression of PPAR‑γ and Bcl‑2 in model mice

Chunying Meng, Zeheng Guo, Dagang Li, Hanwei Li, Jianbin He, Dingguo Wen, Bin Luo

Pages: 1261-1268 Published online on: 06 November 2017

Anti-inflammatory activity of resveratrol prevents inflammation by inhibiting NF‑κB in animal models of acute pharyngitis

Zhong‑Xin Zhou, Shao‑Feng Mou, Xiao‑Qin Chen, Li‑Li Gong, Wen‑Sheng Ge

Pages: 1269-1274 Published online on: 02 November 2017

microRNA‑211 suppresses the growth and metastasis of cervical cancer by directly targeting ZEB1

Guangyuan Chen, Ping Huang, Jiabin Xie, Rihong Li

Pages: 1275-1282 Published online on: 07 November 2017

Attenuated SUMOylation of sirtuin 1 in premature neonates with bronchopulmonary dysplasia

Fengmei Tan, Wenbin Dong, Xiaoping Lei, Xingling Liu, Qingping Li, Lan Kang, Shuai Zhao, Chan Zhang

Pages: 1283-1288 Published online on: 08 November 2017

Protective effects of probucol on Ox-LDL-induced epithelial-mesenchymal transition in human renal proximal tubular epithelial cells via LOX‑1/ROS/MAPK signaling

Bing Bing Zhu, Hao Wang, Yang Feng Chi, Yun Man Wang, Xing Mei Yao, Shuang Liu, Huiling Qiu, Ji Fang, Pei Hao Yin, Xue Mei Zhang, Wen Peng

Pages: 1289-1296 Published online on: 02 November 2017

Preconditioning with carbon monoxide inhalation promotes retinal ganglion cell survival against optic nerve crush via inhibition of the apoptotic pathway

Ruobing Wang, Zeli Chen, Jiangchun Wu, Fangzhou Xia, Qinglei Sun, Aijun Sun, Lin Liu

Pages: 1297-1304 Published online on: 06 November 2017

microRNA-222 promotes tumor growth and confers radioresistance in nasopharyngeal carcinoma by targeting PTEN

Wei Wu, Xi Chen, Shilong Yu, Rui Wang, Ruikun Zhao, Chao Du

Pages: 1305-1310 Published online on: 31 October 2017

Phosphorylation of signal transducer and activator of transcription 3 induced by hyperglycemia is different with that induced by lipopolysaccharide or erythropoietin via receptor‑coupled signaling in cardiac cells

Yu‑Hsin Chiu, Po‑Ming Ku, Yung‑Ze Cheng, Yingxiao Li, Juei‑Tang Cheng, Ho‑Shan Niu

Pages: 1311-1320 Published online on: 06 November 2017

Paeoniflorin influences breast cancer cell proliferation and invasion via inhibition of the Notch‑1 signaling pathway

Jing Zhang, Kun Yu, Xuedong Han, Linlin Zhen, Minmin Liu, Xiwen Zhang, Yi Ren, Jianhua Shi

Pages: 1321-1325 Published online on: 07 November 2017

Decreased expression of interleukin‑37 and its anti‑inflammatory effect in allergic rhinitis

Yang Shen, Xia Ke, Liu Yun, Guo‑Hua Hu, Hou‑Yong Kang, Su‑Ling Hong

Pages: 1333-1339 Published online on: 06 November 2017

Administration of chlorogenic acid alleviates spinal cord injury via TLR4/NF‑κB and p38 signaling pathway anti‑inflammatory activity

Dayong Chen, Dan Pan, Shaolong Tang, Zhihong Tan, Yanan Zhang, Yunfeng Fu, Guohua Lü, Qinghua Huang

Pages: 1340-1346 Published online on: 06 November 2017

Sparstolonin B prevents lumbar intervertebral disc degeneration through toll like receptor 4, NADPH oxidase activation and the protein kinase B signaling pathway

Jianhua Ge, Long Chen, Yunkang Yang, Xiaobo Lu, Zhou Xiang

Pages: 1347-1353 Published online on: 06 November 2017

Cardioprotective effects of ulinastatin against isoproterenol-induced chronic heart failure through the PI3K‑Akt, p38 MAPK and NF-κB pathways

Lin Li, Jianhua Hao, Xian Jiang, Ping Li, Hu Sen

Pages: 1354-1360 Published online on: 02 November 2017

MicroRNA‑212 inhibits the proliferation and invasion of human renal cell carcinoma by targeting FOXA1

Zhigang Tong, Xianfeng Meng, Jinsong Wang, Lixin Wang

Pages: 1361-1367 Published online on: 03 November 2017

Dimethylation of Histone 3 Lysine 9 is sensitive to the epileptic activity, and affects the transcriptional regulation of the potassium channel Kcnj10 gene in epileptic rats

Shao‑Ping Zhang, Man Zhang, Hong Tao, Yan Luo, Tao He, Chun‑Hui Wang, Xiao‑Cheng Li, Ling Chen, Lin‑Na Zhang, Tao Sun, Qi‑Kuan Hu

Pages: 1368-1374 Published online on: 03 November 2017

Downregulation of microRNA‑155 by preoperative administration of valproic acid prevents postoperative seizures by upregulating SCN1A

Zhijie Zhang, Zhenzhong Wang, Bo Zhang, Yan Liu

Pages: 1375-1381 Published online on: 07 November 2017

Off‑target effect of imatinib and nilotinib on human vitamin D3 metabolism

Lysann Kroschwald, Meinolf Suttorp, Josephine Tabea Tauer, Nick Zimmermann, Claudia Günther, Andrea Bauer

Pages: 1382-1388 Published online on: 03 November 2017

MiR-4505 aggravates lipopolysaccharide-induced vascular endothelial injury by targeting heat shock protein A12B

Xu Zhang, Yi Chen, Lei Wang, Qiuxiang Kang, Guifang Yu, Xiaojian Wan, Jiafeng Wang, Keming Zhu

Pages: 1389-1395 Published online on: 02 November 2017
Open Access

Role of innate lymphoid cells in obesity and metabolic disease (Review)

Jirakrit Saetang, Surasak Sangkhathat

Pages: 1403-1412 Published online on: 13 November 2017

Nanoparticles for death‑induced gene therapy in cancer (Review)

Jorge A. Roacho‑Perez, Hugo L. Gallardo‑Blanco, Margarita Sanchez‑Dominguez, Perla E. Garcia‑Casillas, Christian Chapa‑Gonzalez, Celia N. Sanchez‑Dominguez

Pages: 1413-1420 Published online on: 15 November 2017
Open Access

Role of the CRISPR system in controlling gene transcription and monitoring cell fate (Review)

Stella Baliou, Maria Adamaki, Anthony M. Kyriakopoulos, Demetrios A. Spandidos, Michalis Panayiotidis, Ioannis Christodoulou, Vassilis Zoumpourlis

Pages: 1421-1427 Published online on: 16 November 2017
Open Access

Fucoidan inhibits Ca2+ responses induced by a wide spectrum of agonists for G‑protein‑coupled receptors

Hong Wu, Shuibo Gao, Min Fu, Takashi Sakurai, Susumu Terakawa

Pages: 1428-1436 Published online on: 13 November 2017
Open Access

Mesenchymal stem cells overexpressing adrenomedullin improve heart function through antifibrotic action in rats experiencing heart failure

Li Li Li, Cheng Peng, Meiling Zhang, Yumei Liu, Hefei Li, Huibo Chen, Yu Sun, Chunjun Zhu, Yao Zhang

Pages: 1437-1444 Published online on: 14 November 2017
Open Access

HDAC inhibitor LMK‑235 promotes the odontoblast differentiation of dental pulp cells

Zhao Liu, Ting Chen, Qianqian Han, Ming Chen, Jie You, Fuchun Fang, Ling Peng, Buling Wu

Pages: 1445-1452 Published online on: 14 November 2017
Open Access

Therapeutic effects of fibroblast growth factor‑21 against atherosclerosis via the NF‑κB pathway

Yiming Zhang, Zhao Liu, Min Zhou, Changjian Liu

Pages: 1453-1460 Published online on: 16 November 2017
Open Access

Human induced pluripotent stem cell‑derived mesenchymal stem cells alleviate atherosclerosis by modulating inflammatory responses

Hui Shi, Meiling Liang, Weiyan Chen, Xiuting Sun, Xiang Wang, Chenghsun Li, Yiying Yang, Zhisheng Yang, Wutao Zeng

Pages: 1461-1468 Published online on: 15 November 2017
Open Access

Utility of miR‑133a‑3p as a diagnostic indicator for hepatocellular carcinoma: An investigation combined with GEO, TCGA, meta‑analysis and bioinformatics

Hai‑Wei Liang, Xia Yang, Dong‑Yue Wen, Li Gao, Xiang‑Yu Zhang, Zhi‑Hua Ye, Jie Luo, Zu‑Yun Li, Yun He, Yu‑Yan Pang, Gang Chen

Pages: 1469-1484 Published online on: 14 November 2017
Open Access

GATA4 protects against hyperglycemia‑induced endothelial dysfunction by regulating NOX4 transcription

Hongfei Xu, Zhen Wang, Zewei Sun, Yiming Ni, Liangrong Zheng

Pages: 1485-1492 Published online on: 14 November 2017
Open Access

Resveratrol ameliorates inflammatory damage and protects against osteoarthritis in a rat model of osteoarthritis

Yulong Wei, Jie Jia, Xin Jin, Wei Tong, Hongtao Tian

Pages: 1493-1498 Published online on: 13 November 2017
Open Access

CDCA4, a downstream gene of the Nrf2 signaling pathway, regulates cell proliferation and apoptosis in the MCF‑7/ADM human breast cancer cell line

Yuju Xu, Xianghua Wu, Fengxi Li, Daolai Huang, Wenxiang Zhu

Pages: 1507-1512 Published online on: 15 November 2017
Open Access

Genetic mutational testing of Chinese children with familial hematuria with biopsy‑proven FSGS

Yongzhen Li, Ying Wang, Qingnan He, Xiqiang Dang, Yan Cao, Xiaochuan Wu, Shuanghong Mo, Xiaoxie He, Zhuwen Yi

Pages: 1513-1526 Published online on: 10 November 2017
Open Access

Molecular mechanisms of Ellis‑van Creveld gene variations in ventricular septal defect

Fadi Liu, Xiao Liu, Zhenyan Xu, Ping Yuan, Qiongqiong Zhou, Jiejing Jin, Xia Yan, Zixuan Xu, Qing Cao, Jianhua Yu, Yingzhang Cheng, Rong Wan, Kui Hong

Pages: 1527-1536 Published online on: 15 November 2017
Open Access

Effects of oral implants with miR‑122‑modified cell sheets on rat bone marrow mesenchymal stem cells

Dan Shao, Chunfang Wang, Yaping Sun, Lei Cui

Pages: 1537-1544 Published online on: 15 November 2017

Reduced triglyceride accumulation due to overactivation of farnesoid X receptor signaling contributes to impaired liver regeneration following 50% hepatectomy in extra‑cholestatic liver tissue

Wen‑Jun Jia, Shi‑Quan Sun, Luo‑Shun Huang, Qiao‑Li Tang, Yu‑Dong Qiu, Liang Mao

Pages: 1545-1554 Published online on: 10 November 2017
Open Access

Investigation of candidate genes and mechanisms underlying postmenopausal osteoporosis using bioinformatics analysis

Xiaozhong Zhu, Zhiyuan Wang, Yanxun Zhao, Chao Jiang

Pages: 1561-1572 Published online on: 14 November 2017
Open Access

Low dosage of arsenic trioxide inhibits vasculogenic mimicry in hepatoblastoma without cell apoptosis

Feng Zhang, Chun‑Mei Zhang, Shu Li, Kun‑Kun Wang, Bin‑Bin Guo, Yao Fu, Lu‑Yang Liu, Yu Zhang, Hai‑Yu Jiang, Chang‑Jun Wu

Pages: 1573-1582 Published online on: 14 November 2017
Open Access

MicroRNA‑376a inhibits cell proliferation and invasion in glioblastoma multiforme by directly targeting specificity protein 1

Yuefeng Li, Yunxia Wu, Zhigang Sun, Ruiyu Wang, Deliang Ma

Pages: 1583-1590 Published online on: 15 November 2017
Open Access

β‑Ecdysterone promotes autophagy and inhibits apoptosis in osteoporotic rats

Yang‑Hua Tang, Zhen‑Shuang Yue, Da‑Wei Xin, Lin‑Ru Zeng, Zhen‑Fei Xiong, Zhong‑Qing Hu, Can‑Da Xu

Pages: 1591-1598 Published online on: 14 November 2017
Open Access

H89 dihydrochloride hydrate and calphostin C lower the body temperature through TRPV1

Dongyan Bao, Wenqing Zhao, Congcong Dai, Hongmei Wan, Yu Cao

Pages: 1599-1608 Published online on: 15 November 2017
Open Access

17β-estradiol attenuates ovariectomy‑induced bone deterioration through the suppression of the ephA2/ephrinA2 signaling pathway

Lianyong Liu, Lin Zhou, Xiaorong Yang, Qi Liu, Ling Yang, Chao Zheng, Yongling Zhao, Zhenlin Zhang, Xiaohong Luo

Pages: 1609-1616 Published online on: 14 November 2017
Open Access

Effects of chronic scopolamine treatment on cognitive impairment and neurofilament expression in the mouse hippocampus

Jae‑Chul Lee, Joon Ha Park, Ji Hyeon Ahn, Jinseu Park, In Hye Kim, Jeong Hwi Cho, Bich Na Shin, Tae‑Kyeong Lee, Hyunjung Kim, Minah Song, Geum‑Sil Cho, Dae Won Kim, Il Jun Kang, Young‑Myeong Kim, Moo‑Ho Won, Soo Young Choi

Pages: 1625-1632 Published online on: 15 November 2017
Open Access

Effects of Tianxiangdan Granule treatment on atherosclerosis via NF‑κB and p38 MAPK signaling pathways

Long‑Fei Sun, Dong‑Qing An, Gu‑Lijiamali Niyazi, Wen‑Hui Ma, Zheng‑Wei Xu, Yang Xie

Pages: 1642-1650 Published online on: 15 November 2017
Open Access

Protective effects of atorvastatin on cerebral vessel autoregulation in an experimental rabbit model of subarachnoid hemorrhage

Jun‑Hui Chen, Ting Wu, Li‑Kun Yang, Lei Chen, Jie Zhu, Pei‑Pei Li, Xu Hu, Yu‑Hai Wang

Pages: 1651-1659 Published online on: 15 November 2017
Open Access

Anti‑IL‑39 (IL‑23p19/Ebi3) polyclonal antibodies ameliorate autoimmune symptoms in lupus‑like mice

Xiaoqian Wang, Yu Zhang, Zhiding Wang, Xiaoling Liu, Gaizhi Zhu, Gencheng Han, Guojiang Chen, Chunmei Hou, Tianxiao Wang, Beifen Shen, Yan Li, He Xiao, Ning Ma, Renxi Wang

Pages: 1660-1666 Published online on: 14 November 2017
Open Access

VEGF secreted by mesenchymal stem cells mediates the differentiation of endothelial progenitor cells into endothelial cells via paracrine mechanisms

Quanhu Ge, Hongwei Zhang, Jixue Hou, Longfei Wan, Wenzhe Cheng, Xiaoyi Wang, Dan Dong, Congzhe Chen, Jie Xia, Jun Guo, Xueling Chen, Xiangwei Wu

Pages: 1667-1675 Published online on: 14 November 2017
Open Access

Paeoniflorin blocks the proliferation of vascular smooth muscle cells induced by platelet‑derived growth factor‑BB through ROS mediated ERK1/2 and p38 signaling pathways

Xianwei Fan, Jintao Wu, Haitao Yang, Lijie Yan, Shanling Wang

Pages: 1676-1682 Published online on: 15 November 2017
Open Access

Local honokiol application inhibits intimal thickening in rabbits following carotid artery balloon injury

Yu Wang, Danyang Zhao, Jing Sheng, Ping Lu

Pages: 1683-1689 Published online on: 15 November 2017
Open Access

SUMO1/UBC9‑decreased Nox1 activity inhibits reactive oxygen species generation and apoptosis in diabetic retinopathy

Jiaoli Hu, Pengcheng Xue, Xinbang Mao, Lin Xie, Guodong Li, Zhipeng You

Pages: 1690-1698 Published online on: 13 November 2017
Open Access

INSIG2 rs7566605 single nucleotide variant and global DNA methylation index levels are associated with weight loss in a personalized weight reduction program

Francesca Pirini, Sebastian Rodriguez‑Torres, Bola Grace Ayandibu, María Orera‑Clemente, Alberto Gonzalez‑de la Vega, Fahcina Lawson, Roland J. Thorpe, David Sidransky, Rafael Guerrero‑Preston

Pages: 1699-1709 Published online on: 14 November 2017
Open Access

NG25, an inhibitor of transforming growth factor‑β‑activated kinase 1, ameliorates neuronal apoptosis in neonatal hypoxic‑ischemic rats

Hua Wang, Zhong Chen, Yu Li, Qiaoyun Ji

Pages: 1710-1716 Published online on: 10 November 2017
Open Access

Therapeutic effect of ulinastatin on pulmonary fibrosis via downregulation of TGF‑β1, TNF‑α and NF‑κB

Dejun Li, Hongsheng Ji, Bao Zhao, Chunyang Xu, Wenjun Xia, Lihui Han, Dongqing Yu, Yuanrong Ju, Changjun Jin

Pages: 1717-1723 Published online on: 14 November 2017
Open Access

Effect of cigarette smoke extract and nicotine on the expression of thrombomodulin and endothelial protein C receptor in cultured human umbilical vein endothelial cells

Yujie Wei, Bin Lai, Huiliang Liu, Yi Li, Wang Zhen, Ling Fu

Pages: 1724-1730 Published online on: 15 November 2017
Open Access

Therapeutic effects of mesenchymal stem cells combined with short hairpin RNA on liver injury induced by hepatitis B virus infection

Di Liu, Lin Liu, Lizheng Wang, Sizhu Duan, Yanan Song, Meng Qu, Nan Gao, Jiaxin Wu, Haihong Zhang, Hui Wu, Wei Kong, Bin Yu, Xianghui Yu

Pages: 1731-1741 Published online on: 15 November 2017
Open Access

miR‑185 inhibits non‑small cell lung cancer cell proliferation and invasion through targeting of SOX9 and regulation of Wnt signaling

Zhengwen Lei, Hongcan Shi, Wei Li, Duonan Yu, Feiyang Shen, Xi Yu, Dan Lu, Chao Sun, Kai Liao

Pages: 1742-1752 Published online on: 14 November 2017
Open Access

Effect of prehypertensive losartan therapy on AT1R and ATRAP methylation of adipose tissue in the later life of high‑fat‑fed spontaneously hypertensive rats

Tingjun Wang, Guili Lian, Xiaoqi Cai, Zhihong Lin, Liangdi Xie

Pages: 1753-1761 Published online on: 15 November 2017
Open Access

SK channels participate in the formation of after burst hyperpolarization and partly inhibit the burst strength of epileptic ictal discharges

Yian Huang, Xu Liu, Guoxiang Wang, Yun Wang

Pages: 1762-1774 Published online on: 15 November 2017
Open Access

Matrine suppresses cardiac fibrosis by inhibiting the TGF‑β/Smad pathway in experimental diabetic cardiomyopathy

Yong Zhang, Lei Cui, Gongchang Guan, Junkui Wang, Chuan Qiu, Tielin Yang, Yan Guo, Zhongwei Liu

Pages: 1775-1781 Published online on: 14 November 2017
Open Access

Application of next‑generation sequencing to identify mitochondrial mutations: Study on m.7511T>C in patients with hearing loss

Urszula Lechowicz, Agnieszka Pollak, Agnieszka Frączak, Małgorzata Rydzanicz, Piotr Stawiński, Artur Lorens, Piotr H. Skarżyński, Henryk Skarżyński, Rafał Płoski, Monika Ołdak

Pages: 1782-1790 Published online on: 15 November 2017

Elevated serum levels of lipoprotein‑associated phospholipase A2 predict mortality rates in patients with sepsis

Zhongwei Huang, Haiyan Jiang, Xiaohui Cui, Guiwen Liang, Yu Chen, Ting Wang, Zhichao Sun, Lei Qi

Pages: 1791-1798 Published online on: 13 November 2017

Grape seed proanthocyanidin extract attenuates varicocele‑induced testicular oxidative injury in rats by activating the Nrf2‑antioxidant system

Yong Wang, Fan Chen, Ming Liang, Shouzhen Chen, Yaofeng Zhu, Zhichuan Zou, Benkang Shi

Pages: 1799-1806 Published online on: 10 November 2017

Homology modeling and prediction of B‑cell and T‑cell epitopes of the house dust mite allergen Der f 20

Feixiang Teng, Lili Yu, Jinxia Sun, Nan Wang, Yubao Cui

Pages: 1807-1812 Published online on: 15 November 2017

Protective effects of fucoidan against hyperoxic lung injury via the ERK signaling pathway

Minghao Nie, Yan Wang, Yanhong Lu, Ying Yuan, Yingying Liu, Xiurong Li

Pages: 1813-1818 Published online on: 10 November 2017

P2Y1 receptor antagonists mitigate oxygen and glucose deprivation‑induced astrocyte injury

Hui Guo, Zhong‑Qiang Liu, Hui Zhou, Zhi‑Ling Wang, Yu‑Hong Tao, Yu Tong

Pages: 1819-1824 Published online on: 15 November 2017

miR‑455‑5p promotes cell invasion and migration in breast cancer

Tuerxunjiang Aili, Xuelaiti Paizula, Aisikeer Ayoufu

Pages: 1825-1832 Published online on: 16 November 2017

Integrated bioinformatics analysis of the osteoarthritis‑associated microRNA expression signature

Xi Wang, Yujie Ning, Bing Zhou, Lei Yang, Yingting Wang, Xiong Guo

Pages: 1833-1838 Published online on: 14 November 2017

Effects of SCN9A gene modification on Na+ channel and the expression of nerve growth factor in a rat model of diarrhea‑predominant irritable bowel syndrome

Yong‑Yan Cai, Chen Li, Zhi‑Xin Yan, Na Ma, Fang‑Fang Li

Pages: 1839-1846 Published online on: 14 November 2017

Mechanical strain promotes osteogenic differentiation of bone mesenchymal stem cells from ovariectomized rats via the phosphoinositide 3‑kinase/Akt signaling pathway

Ningjuan Ouyang, Peng Zhang, Runqing Fu, Guofang Shen, Lingyong Jiang, Bing Fang

Pages: 1855-1862 Published online on: 13 November 2017

Beneficial effect of resveratrol on α‑naphthyl isothiocyanate‑induced cholestasis via regulation of the FXR pathway

Lili Ding, Binfeng Zhang, Jinmei Li, Li Yang, Zhengtao Wang

Pages: 1863-1872 Published online on: 14 November 2017

The ‑α3.7 deletion in α‑globin genes increases the concentration of fetal hemoglobin and hemoglobin A2 in a Saudi Arabian population

J. Francis Borgio, Sayed Abdulazeez, Noor B. Almandil, Zaki A. Naserullah, Sana Al‑Jarrash, Ahmed M. Al‑Suliman, Huda Ismail Elfakharay, Fuad S. Qaw, Fatimah I. Alabdrabalnabi, Mohammed A. Alkhalifah, Mohammed Shakil Akhtar, Hatem Qutub, Amein K. Al‑Ali

Pages: 1879-1884 Published online on: 13 November 2017

Modulation of TGF‑β activity by latent TGF‑β‑binding protein 1 in human osteoarthritis fibroblast‑like synoviocytes

Xinli Wang, Chuan Dong, Nan Li, Qiong Ma, Zhe Yun, Chengkui Cai, Ming An, Baoan Ma

Pages: 1893-1900 Published online on: 15 November 2017

Anti‑inflammatory effect of Migri‑Heal® in an in vitro inflammatory model of primary mixed glial cells

Mahmoud Hassani, Farzaneh Sabouni, Mohammad Ansari, Solaleh Emamgholipour, Mohammad‑Sadegh Fallah, Shah‑Sanam Abbasi, Saeed Ansari Majd

Pages: 1901-1906 Published online on: 13 November 2017

Overexpression of microRNA-146 protects against oxygen-glucose deprivation/recovery-induced cardiomyocyte apoptosis by inhibiting the NF-κB/TNF-α signaling pathway

Wenwu Zhang, Mengmeng Shao, Xiaojie He, Benji Wang, Yuechun Li, Xianyang Guo

Pages: 1913-1918 Published online on: 15 November 2017

Reduced miRNA‑214 expression in oral mucosa contributes to the pathogenesis of oral lichen planus by targeting CD44

Haiyan Zheng, Shaohui Li

Pages: 1919-1925 Published online on: 10 November 2017

miR‑218 inhibits the proliferation of human glioma cells through downregulation of Yin Yang 1

Yong Gao, Laisheng Sun, Zicheng Wu, Chengmin Xuan, Junxia Zhang, Yongping You, Xincheng Chen

Pages: 1926-1932 Published online on: 15 November 2017

Effect of moesin phosphorylation on high‑dose sphingosine‑1‑phosphate‑induced endothelial responses

Yan Xiao, Jie Wu, Yongjun Yuan, Xiaohua Guo, Bo Chen, Qiaobing Huang

Pages: 1933-1939 Published online on: 13 November 2017

Long noncoding RNA‑ATB promotes cell proliferation, migration and invasion in gastric cancer

Ying Chen, Guoqing Wei, Hongwei Xia, Qiulin Tang, Feng Bi

Pages: 1940-1946 Published online on: 15 November 2017

The long noncoding RNA cancer susceptibility candidate 2 inhibits tumor progression in osteosarcoma

Lingyun Lu, Zhehao Dai, Qing Luo, Guohua Lv

Pages: 1947-1953 Published online on: 15 November 2017

An RNA‑sequencing study identifies candidate genes for angiotensin II‑induced cardiac remodeling

Jin Shu, Zhanwen Liu, Li Jin, Haiya Wang

Pages: 1954-1962 Published online on: 14 November 2017

Curcumin improves diabetes mellitus‑associated cerebral infarction by increasing the expression of GLUT1 and GLUT3

Mingyu Xia, Zankai Ye, Yanfeng Shi, Libo Zhou, Yang Hua

Pages: 1963-1969 Published online on: 15 November 2017

iASPP, a microRNA‑124 target, is aberrantly expressed in astrocytoma and regulates malignant glioma cell migration and viability

Xiangrong Liu, Jun Kang, Si Sun, Yumin Luo, Xunming Ji, Xianwei Zeng, Shangfeng Zhao

Pages: 1970-1978 Published online on: 15 November 2017

The regulatory role of Fos related antigen‑1 in inflammatory bowel disease

Xianren Wang, Renle Guo, Yanfeng Lv, Rongzhan Fu

Pages: 1979-1985 Published online on: 15 November 2017

Fli‑1 promotes metastasis by regulating MMP2 signaling in hepatocellular carcinoma

Huiling Wang, Yingliang Ou, Jinrui Ou, Zhixiang Jian

Pages: 1986-1992 Published online on: 14 November 2017

Cytochrome c is important in apoptosis of labial glands in primary Sjogren's syndrome

Yuanyuan Kang, Yan Sun, Ying Zhang, Zhe Wang

Pages: 1993-1997 Published online on: 15 November 2017

TWEAK/Fn14 promotes oxidative stress through AMPK/PGC‑1α/MnSOD signaling pathway in endothelial cells

Hengdao Liu, Hui Peng, Hong Xiang, Lingli Guo, Ruifang Chen, Shaoli Zhao, Wei Chen, Pan Chen, Hongwei Lu, Shuhua Chen

Pages: 1998-2004 Published online on: 15 November 2017

microRNA‑625 targets Yes‑associated protein 1 to suppress cell proliferation and invasion of osteosarcoma

Zheng Luo, Gang Wu, Daiyang Zhang, Jun Liu, Renguo Ran

Pages: 2005-2011 Published online on: 15 November 2017

Neuroprotective effect of tanshinone IIA weakens spastic cerebral palsy through inflammation, p38MAPK and VEGF in neonatal rats

Wen‑Luo Zhang, Yue‑An Cao, Jing Xia, Li Tian, Lu Yang, Chao‑Sheng Peng

Pages: 2012-2018 Published online on: 15 November 2017

Curcumin reverses tobacco smoke‑induced epithelial‑mesenchymal transition by suppressing the MAPK pathway in the lungs of mice

Zhaofeng Liang, Rui Wu, Wei Xie, Mingming Zhu, Chunfeng Xie, Xiaoting Li, Jianyun Zhu, Weiwei Zhu, Jieshu Wu, Shanshan Geng, Wenrong Xu, Caiyun Zhong, Hongyu Han

Pages: 2019-2025 Published online on: 13 November 2017

Gambogic acid inhibits spinal cord injury and inflammation through suppressing the p38 and Akt signaling pathways

Qiao Fu, Chaojian Li, Lehua Yu

Pages: 2026-2032 Published online on: 10 November 2017

The role of dual‑specificity phosphatase 1 and protein phosphatase 1 in β2‑adrenergic receptor‑mediated inhibition of extracellular signal regulated kinase 1/2 in triple negative breast cancer cell lines

Matilda Merve Tuglu, Saber Yari Bostanabad, Gozde Ozyon, Başak Dalkiliç, Hakan Gurdal

Pages: 2033-2043 Published online on: 15 November 2017

Cellular properties of the fermented microalgae Pavlova lutheri and its isolated active peptide in osteoblastic differentiation of MG‑63 cells

Zhong‑Ji Qian, Bomi Ryu, Kyong‑Hwa Kang, Soo‑Jin Heo, Do‑Hyung Kang, Sung Yong Bae, Sun‑Joo Park, Jae‑Il Kim, Young‑Mog Kim, Yong‑Tae Kim, Won‑Kyo Jung

Pages: 2044-2050 Published online on: 15 November 2017

miR‑660‑5p is associated with cell migration, invasion, proliferation and apoptosis in renal cell carcinoma

Tao He, Peijie Chen, Lu Jin, Jia Hu, Yifan Li, Liang Zhou, Shangqi Yang, Xiangming Mao, Yaoting Gui, Yun Chen, Yongqing Lai

Pages: 2051-2060 Published online on: 14 November 2017

Mechanism of free radical generation in platelets and primary hepatocytes: A novel electron spin resonance study

Chiun‑Lang Wang, Po‑Sheng Yang, Jeng‑Ting Tsao, Thanasekaran Jayakumar, Meng‑Jiy Wang, Joen‑Rong Sheu, Duen‑Suey Chou

Pages: 2061-2069 Published online on: 14 November 2017

SRPK1‑siRNA suppresses K562 cell growth and induces apoptosis via the PARP‑caspase3 pathway

Hailian Wang, Wei Ge, Wen Jiang, Dong Li, Xiuli Ju

Pages: 2070-2076 Published online on: 13 November 2017
Journal Cover

January 2018
Volume 17 Issue 1

Print ISSN: 1791-2997
Online ISSN: 1791-3004

2016 Impact Factor: 1.692
Ranked #19/128 Medicine Research and Experimental
(total number of cites)

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