Journal Articles

Open Access

Regulatory B cells in infectious disease (Review)

You‑Chao Dai, Jixin Zhong, Jun‑Fa Xu

Pages: 3-10 Published online on: 18 May 2017
Open Access

Research and progress on ClC‑2 (Review)

Hongwei Wang, Minghui Xu, Qingjie Kong, Peng Sun, Fengyun Yan, Wenying Tian, Xin Wang

Pages: 11-22 Published online on: 18 May 2017

Proliferation‑inhibiting pathways in liver regeneration (Review)

Menggang Liu, Ping Chen

Pages: 23-35 Published online on: 19 May 2017
Open Access

Galectin‑9 ameliorates fulminant liver injury

Tomoko Tadokoro, Asahiro Morishita, Teppei Sakamoto, Shintaro Fujihara, Koji Fujita, Shima Mimura, Kyoko Oura, Takako Nomura, Joji Tani, Hirohito Yoneyama, Hisakazu Iwama, Takashi Himoto, Toshiro Niki, Mitsuomi Hirashima, Tsutomu Masaki

Pages: 36-42 Published online on: 18 May 2017
Open Access

DEC2 expression antagonizes cisplatin‑induced apoptosis in human esophageal squamous cell carcinoma

Hidenobu Sato, Yunyan Wu, Yukio Kato, Qiang Liu, Hideaki Hirai, Tadashi Yoshizawa, Satoko Morohashi, Jun Watanabe, Hiroshi Kijima

Pages: 43-48 Published online on: 11 May 2017
Open Access

PPAR-α improves the recovery of lung function following acute respiratory distress syndrome by suppressing the level of TGF-β1

Yang Liu, Liping Xie, Mingquan Yang, Xiaofei Tan, Yonghong Zeng, Gang Zheng, Youying Chen, Ping Chen

Pages: 49-56 Published online on: 10 May 2017
Open Access

Flow control effect of necrostatin-1 on cell death of the NRK-52E renal tubular epithelial cell line

Jialun Luo, Yiming Tao, Xinling Liang, Yuanhan Chen, Li Zhang, Fen Jiang, Shuangxin Liu, Zhiming Ye, Zhilian Li, Wei Shi

Pages: 57-62 Published online on: 09 May 2017
Open Access

Differential effects of p38 and Erk1/2 on the chondrogenic and osteogenic differentiation of dental pulp stem cells

Pengfei Ba, Xiaoyu Duan, Guo Fu, Shuyan Lv, Pishan Yang, Qinfeng Sun

Pages: 63-68 Published online on: 10 May 2017
Open Access

Long non‑coding RNA AB019562 promotes cell proliferation and metastasis in human hepatocellular carcinoma

Fan Wu, Jie Li, Xin Du, Weisan Zhang, Ping Lei, Qiang Zhang

Pages: 69-74 Published online on: 19 May 2017
Open Access

Analysis of the CDR3 length repertoire and the diversity of T cell receptor α and β chains in swine CD4+ and CD8+ T lymphocytes

Chun‑Yan Wang, Yong‑Xiang Fang, Guo‑Hua Chen, Huai‑Jie Jia, Shuang Zeng, Xiao‑Bing He, Yuan Feng, Shou‑Jie Li, Qi‑Wang Jin, Wen‑Yu Cheng, Zhi‑Zhong Jing

Pages: 75-86 Published online on: 18 May 2017
Open Access

Differentiation of nestin‑negative human hair follicle outer root sheath cells into neurons in vitro

Wei Wu, Xiao‑Li Wu, Yu‑Qing Ji, Zhen Gao

Pages: 95-100 Published online on: 16 May 2017
Open Access

Combination of bortezomib and daunorubicin in the induction of apoptosis in T-cell acute lymphoblastic leukemia

Xin Du, Jia Tong, Hongying Lu, Cong He, Shenghong Du, Peimin Jia, Weili Zhao, Hanzhang Xu, Junmin Li, Zhixiang Shen, Yingli Wu, Jianhua Tong, Li Zhou

Pages: 101-108 Published online on: 09 May 2017
Open Access

Effects of octreotide on hepatic glycogenesis in rats with high fat diet‑induced obesity

Xiao‑Xia Wang, Ting Ye, Mao Li, Xian Li, Ou Qiang, Cheng‑Wei Tang, Rui Liu

Pages: 109-118 Published online on: 16 May 2017
Open Access

Effect of fasudil on cognitive function following status convulsion in rats

Rong He, Wei Han, Xiaojie Song, Xiaoju Tang, Li Cheng, Li Jiang

Pages: 119-126 Published online on: 19 May 2017
Open Access

High‑throughput sequencing analyses of oral microbial diversity in healthy people and patients with dental caries and periodontal disease

Tingtao Chen, Yan Shi, Xiaolei Wang, Xin Wang, Fanjing Meng, Shaoguo Yang, Jian Yang, Hongbo Xin

Pages: 127-132 Published online on: 17 May 2017
Open Access

Pre‑treatment with Chrysanthemum indicum Linné extract protects pyramidal neurons from transient cerebral ischemia via increasing antioxidants in the gerbil hippocampal CA1 region

In Hye Kim, Tae‑Kyeong Lee, Jeong Hwi Cho, Jae‑Chul Lee, Joon Ha Park, Ji Hyeon Ahn, Bich‑Na Shin, Bai Hui Chen, Hyun‑Jin Tae, Yang Hee Kim, Jong‑Dai Kim, Young‑Myeong Kim, Moo‑Ho Won, Il Jun Kang

Pages: 133-142 Published online on: 17 May 2017
Open Access

miRNA‑1271 inhibits cell proliferation in neuroglioma by targeting fibronectin 1

Jian Gong, Zhao‑Xia Wang, Zhen‑Ying Liu

Pages: 143-150 Published online on: 19 May 2017
Open Access

Overexpression of stromal interaction molecule 1 may promote epithelial‑mesenchymal transition and indicate poor prognosis in gastric cancer

Guobin Wu, Yong Li, Bibo Tan, Liqiao Fan, Qun Zhao, Yü Liu, Zhidong Zhang

Pages: 151-158 Published online on: 18 May 2017
Open Access

C-terminus of OX2R significantly affects downstream signaling pathways

Chunmei Wang, Chao Xu, Minghui Liu, Yanyou Pan, Bo Bai, Jing Chen

Pages: 159-166 Published online on: 09 May 2017
Open Access

MicroRNA‑141 inhibits the self‑renewal of glioblastoma stem cells via Jagged1

Xianfeng Gao, Xiaobo Zhu, Yang Sun, Jingwei Liu

Pages: 167-173 Published online on: 17 May 2017
Open Access

Mitochondrial activity and oxidative stress functions are influenced by the activation of AhR-induced CYP1A1 overexpression in cardiomyocytes

Bing Zhou, Xi Wang, Feng Li, Yingting Wang, Lei Yang, Xiaolong Zhen, Wuhong Tan

Pages: 174-180 Published online on: 12 May 2017
Open Access

Microarray analysis of differentially expressed genes in L929 mouse fibroblast cells exposed to leptin and hypoxia

Ping Ouyang, Sen Wang, He Zhang, Zhigang Huang, Pei Wei, Ye Zhang, Zhuguo Wu, Tao Li

Pages: 181-191 Published online on: 17 May 2017
Open Access

Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats

Xinwei Liu, Jingdong Zhang, Wenfeng Han, Yu Wang, Yunen Liu, Yubiao Zhang, Dapeng Zhou, Liangbi Xiang

Pages: 192-200 Published online on: 09 May 2017
Open Access

Hypospadias in a male infant with an unusual mosaic 45,X/46,X,psu idic(Y)(p11.32)/46,XY and haploinsufficiency of SHOX: A case report

Yan‑Mei Si, Yuan Dong, Wei Wang, Ke‑Yan Qi, Xin Wang

Pages: 201-207 Published online on: 10 May 2017
Open Access

Inhibitors of PARP-1 exert inhibitory effects on the biological characteristics of hepatocellular carcinoma cells in vitro

Xiaorong Mao, Senrong Du, Zhongxia Yang, Liting Zhang, Xuebin Peng, Ni Jiang, Haiyu Zhou

Pages: 208-214 Published online on: 10 May 2017
Open Access

Proteomic analysis of differentially expressed proteins in kidneys of brain dead rabbits

Ling Li, Ning Li, Chongxiang He, Wei Huang, Xiaoli Fan, Zibiao Zhong, Yanfeng Wang, Qifa Ye

Pages: 215-223 Published online on: 19 May 2017

High expression of PFTK1 in cancer cells predicts poor prognosis in colorectal cancer

Youjun Mao, Yuqing Jia, Huijun Zhu, Wei Wang, Qin Jin, Fang Huang, Shu Zhang, Xiaoqiang Li

Pages: 224-230 Published online on: 10 May 2017
Open Access

Expression of c-FLIP in a rat model of sepsis and its effects on endothelial apoptosis

Lei Shen, Zhengda Sun, Feng Zhao, Wei Wang, Wenhong Zhang, Hechen Zhu

Pages: 231-237 Published online on: 10 May 2017
Open Access

Identification of miR‑124a as a novel diagnostic and prognostic biomarker in non‑small cell lung cancer for chemotherapy

Pei Luo, Qing Yang, Le‑Le Cong, Xiao‑Feng Wang, Yu‑Sheng Li, Xiao‑Ming Zhong, Ru‑Ting Xie, Cheng‑You Jia, Hui‑Qiong Yang, Wen‑Ping Li, Xian‑Ling Cong, Qing Xia, Da Fu, Qing‑Hua Zeng, Yu‑Shui Ma

Pages: 238-246 Published online on: 17 May 2017
Open Access

miR-590 regulates WT1 during proliferation of G401 cells

Liyi Hong, Xu Zhao, Xuejun Shao, Hong Zhu

Pages: 247-253 Published online on: 10 May 2017
Open Access

High expression levels of the D686N Parkinson's disease mutation in VPS35 induces α-synuclein-dependent toxicity in yeast

Yi Huang, Xiang Chen, Xiaofei He, Caifeng Guo, Xicui Sun, Fengyin Liang, Simei Long, Xilin Lu, Luyang Feng, Wenyuan Guo, Yixuan Zeng, Zhong Pei

Pages: 254-262 Published online on: 09 May 2017
Open Access

Embryotoxicity estimation of commonly used compounds with embryonic stem cell test

Hui Liu, Caiping Ren, Weidong Liu, Xingjun Jiang, Lei Wang, Bin Zhu, Wei Jia, Jianxing Lin, Jun Tan, Xiuying Liu

Pages: 263-271 Published online on: 09 May 2017
Open Access

A proteomic analysis identifies candidate early biomarkers to predict ovarian hyperstimulation syndrome in polycystic ovarian syndrome patients

Lan Wu, Yazhou Sun, Jun Wan, Ting Luan, Qing Cheng, Yong Tan

Pages: 272-280 Published online on: 18 May 2017
Open Access

Bioinformatic analysis of the effects and mechanisms of decitabine and cytarabine on acute myeloid leukemia

Shiyong Zhou, Pengfei Liu, Huilai Zhang

Pages: 281-287 Published online on: 12 May 2017
Open Access

Sanguinarine protects against ovariectomy‑induced osteoporosis in mice

Yan Ma, Junjie Chu, Jianjun Ma, Lei Ning, Ke Zhou, Xiangqian Fang

Pages: 288-294 Published online on: 11 May 2017

Neokestose suppresses the growth of human melanoma A2058 cells via inhibition of the nuclear factor‑κB signaling pathway

Jiann‑Shing Wu, Jan‑Yi Chang, C. Will Chen, Ming‑Tse Lin, Dey‑Chyi Sheu, Shun‑Mei Lee

Pages: 295-300 Published online on: 17 May 2017

Molecular analysis of the mouse brain exposed to chronic mild stress: The influence of hepatocyte nuclear factor 4α on physiological homeostasis

Kaoru Ikubo, Kyosuke Yamanishi, Nobutaka Doe, Takuya Hashimoto, Miho Sumida, Yuko Watanabe, Yosif El‑Darawish, Wen Li, Haruki Okamura, Hiromichi Yamanishi, Hisato Matsunaga

Pages: 301-309 Published online on: 11 May 2017

Low‑level mechanical vibration enhances osteoblastogenesis via a canonical Wnt signaling‑associated mechanism

Heqi Gao, Mingming Zhai, Pan Wang, Xuhui Zhang, Jing Cai, Xiaofei Chen, Guanghao Shen, Erping Luo, Da Jing

Pages: 317-324 Published online on: 19 May 2017

Role of X‑linked inhibitor of apoptosis‑associated factor‑1 in vasculogenic mimicry in ovarian cancer

Yunxia Wang, Peishu Liu, Xietong Wang, Hongluan Mao

Pages: 325-330 Published online on: 17 May 2017

RPN11 deubiquitinase promotes proliferation and migration of breast cancer cells

Guoqing Luo, Ningdong Hu, Xu Xia, Jingjing Zhou, Changsheng Ye

Pages: 331-338 Published online on: 16 May 2017

Spilanthes acmella inhibits inflammatory responses via inhibition of NF-κB and MAPK signaling pathways in RAW 264.7 macrophages

Young‑Chang Cho, Tran The Bach, Ba Reum Kim, Huong Lan Vuong, Sayeon Cho

Pages: 339-346 Published online on: 09 May 2017

Elevated SLC26A4 gene promoter methylation is associated with the risk of presbycusis in men

Jin Xu, Jiachen Zheng, Wanjing Shen, Lili Ma, Ming Zhao, Xubo Wang, Jiyuan Tang, Jihong Yan, Zhenhua Wu, Zuquan Zou, Shizhong Bu, Yang Xi

Pages: 347-352 Published online on: 10 May 2017

Mus musculus-microRNA-449a ameliorates neuropathic pain by decreasing the level of KCNMA1 and TRPA1, and increasing the level of TPTE

Shan Lu, Sichao Ma, Yunyun Wang, Tao Huang, Zhihua Zhu, Guoqing Zhao

Pages: 353-360 Published online on: 10 May 2017

Effects of unfractionated heparin and rivaroxaban on the expression of heparanase and fibroblast growth factor 2 in human osteoblasts

Jingjun Xia, Wei Sheng, Liubao Pei, Ning Li, Zhipeng Zhang, Jialiang Wang, Jianing Zu, Nanxiang Wang, Duanyang Wang

Pages: 361-366 Published online on: 10 May 2017

Reduced expression of follicle stimulating hormone receptor mRNA and protein in pregnancies complicated by pre‑eclampsia

Mo Li, Yifan Jia, Yan Ling, Yilu Chen, Lu Zhang, Dan Luo, Lidan Lai, Meijun Guo, Dalei Zhang, Min Ren, Hong Xu, Haibin Kuang

Pages: 367-372 Published online on: 18 May 2017

Demethylzeylasteral ameliorates inflammation in a rat model of unilateral ureteral obstruction through inhibiting activation of the NF‑κB pathway

Qiang Wang, Yanmei Xiao, Tongwei Liu, Haibo Yuan, Chunwu Li

Pages: 373-379 Published online on: 16 May 2017

Luteolin-induced apoptosis through activation of endoplasmic reticulum stress sensors in pheochromocytoma cells

Kisang Kwon, Young‑Sook Kwon, Seung‑Whan Kim, Kweon Yu, Kyung‑Ho Lee, O‑Yu Kwon

Pages: 380-386 Published online on: 12 May 2017

Neuropeptide Y suppresses epileptiform discharges by regulating AMPA receptor GluR2 subunit in rat hippocampal neurons

Wei Bu, Wen‑Qing Zhao, Wen‑Ling Li, Chang‑Zheng Dong, Zhe Zhang, Qi‑Jun Li

Pages: 387-395 Published online on: 10 May 2017

Synergistic protective effect of FTY720 and vitamin E against simulated cerebral ischemia in vitro

Xin Pang, Xuening Hou

Pages: 396-402 Published online on: 11 May 2017

Contribution of methylglyoxal to delayed healing of bone injury in diabetes

Takao Aikawa, Hidenori Matsubara, Shuhei Ugaji, Junichi Shirakawa, Ryoji Nagai, Seiichi Munesue, Ai Harashima, Yasuhiko Yamamoto, Hiroyuki Tsuchiya

Pages: 403-409 Published online on: 16 May 2017

Whole‑exome sequencing identifies a novel mutation (R367G) in SCN5A to be associated with familial cardiac conduction disease

Rong Yu, Xue‑Feng Fan, Chan Chen, Zheng‑Hua Liu

Pages: 410-414 Published online on: 17 May 2017

Correlation of four potential biomarkers of liver fibrosis with liver function and grade of hepatic fibrosis in a neonatal cholestatic rat model

Ning Tang, Yaping Zhang, Zeyu Liu, Xuemei Ai, Qinghong Liang

Pages: 415-421 Published online on: 16 May 2017

PER2 is downregulated by the LPS-induced inflammatory response in synoviocytes in rheumatoid arthritis and is implicated in disease susceptibility

Hwayoung Lee, Seong‑Su Nah, Sung‑Hae Chang, Hyung‑Ki Kim, Jun‑Tack Kwon, Sanghyun Lee, Ik‑Hyun Cho, Sang Won Lee, Young Ock Kim, Seung‑Jae Hong, Hak‑Jae Kim

Pages: 422-428 Published online on: 11 May 2017

How much medium do you use for cell culture? Medium volume influences mineralization and osteoclastogenesis in vitro

Yoshitaka Yoshimura, Takashi Kikuiri, Tomokazu Hasegawa, Mino Matsuno, Hajime Minamikawa, Yoshiaki Deyama, Kuniaki Suzuki

Pages: 429-434 Published online on: 19 May 2017

Effects of exercise on mature or precursor brain‑derived neurotrophic factor pathways in ovariectomized rats

Joon‑Ki Park, Young‑Pyo Hong, Sam‑Jun Lee

Pages: 435-440 Published online on: 19 May 2017

hTERT C250T promoter mutation and telomere length as a molecular markers of cancer progression in patients with head and neck cancer

Wojciech Barczak, Wiktoria M. Suchorska, Agnieszka Sobecka, Karolina Bednarowicz, Piotr Machczynski, Pawel Golusinski, Blazej Rubis, Michal M. Masternak, Wojciech Golusinski

Pages: 441-446 Published online on: 17 May 2017

Increased production of human fibroblast growth factor 17 in Escherichia coli and proliferative activity in NIH3T3 cells

Meiyu Wu, Na Song, Jiliang Cheng, Yang Zhao, Nazi Chen, Jisheng Ma, Xiaokun Li, Chao Jiang, Haijun Wang

Pages: 447-452 Published online on: 11 May 2017

Dexamethasone reduces side population fraction through downregulation of ABCG2 transporter in MCF-7 breast cancer cells

Jong Bin Kim, Sung Eun Hwang, Sang‑Pil Yoon

Pages: 453-458 Published online on: 10 May 2017

Inhibition of prostate cancer RM1 cell growth in vitro by hydroxyapatite nanoparticle‑delivered short hairpin RNAs against Stat3

Zuowen Liang, Hongliang Wang, Baofeng Guo, Fubiao Li, Jinsha Liu, Zhewen Liu, Libo Xu, Wenjing Yun, Xuejian Zhao, Ling Zhang

Pages: 459-465 Published online on: 16 May 2017

MicroRNA‑296 targets AKT2 in pancreatic cancer and functions as a potential tumor suppressor

Hailing Li, Jilin Li, Baolin Shi, Feng Chen

Pages: 466-472 Published online on: 18 May 2017

Identification of a missense HOXD13 mutation in a Chinese family with syndactyly type I-c using exome sequencing

Hao Deng, Ting Tan, Quanyong He, Qiongfen Lin, Zhijian Yang, Anding Zhu, Liping Guan, Jingjing Xiao, Zhi Song, Yi Guo

Pages: 473-477 Published online on: 11 May 2017

Tamoxifen promotes apoptosis and inhibits invasion in estrogen‑positive breast cancer MCF‑7 cells

Wei Li, Xingpeng Shi, Yan Xu, Jianmei Wan, Shaohua Wei, Ran Zhu

Pages: 478-484 Published online on: 18 May 2017
Open Access

Effects of maternal acrolein exposure during pregnancy on testicular testosterone production in fetal rats

Yuzhuo Yang, Zhe Zhang, Hongliang Zhang, Kai Hong, Wenhao Tang, Lianming Zhao, Haocheng Lin, Defeng Liu, Jiaming Mao, Han Wu, Hui Jiang

Pages: 491-498 Published online on: 25 May 2017
Open Access

Clinical significance and prognostic value of SOX7 expression in liver and pancreatic carcinoma

Jian Wang, Shengmin Zhang, Jiamian Wu, Zhuocai Lu, Jianrong Yang, Hongsheng Wu, Hao Chen, Bo Lin, Tiansheng Cao

Pages: 499-506 Published online on: 31 May 2017
Open Access

A comparative study of the influence of two types of PHEMA stents on the differentiation of ASCs to myocardial cells

Shen Lao, Jing Xu, Yunqi Liu, Songwang Cai, Lin Lin, Junhang Zhang, Dongmei Cai, Shengli Yin

Pages: 507-514 Published online on: 01 June 2017
Open Access

Remote ischemic postconditioning confers neuroprotective effects via inhibition of the BID-mediated mitochondrial apoptotic pathway

Xiaoying Gao, Yun Liu, Yuying Xie, Ying Wang, Sihua Qi

Pages: 515-522 Published online on: 30 May 2017
Open Access

Schisandrin B attenuates the inflammatory response, oxidative stress and apoptosis induced by traumatic spinal cord injury via inhibition of p53 signaling in adult rats

D. Q. Xin, Z. M. Hu, H. J. Huo, X. J. Yang, D. Han, W. H. Xing, Y. Zhao, Q. H. Qiu

Pages: 533-538 Published online on: 25 May 2017
Open Access

Effects of demethoxycurcumin on the viability and apoptosis of skin cancer cells

Yaoqun Wu, Pei Zhang, Hongyun Yang, Yong Ge, Yong Xin

Pages: 539-546 Published online on: 31 May 2017
Open Access

Effects of cryopreservation on excretory function, cellular adhesion molecules and vessel lumen formation in human umbilical vein endothelial cells

Guoping Cai, Binbin Lai, Huaxing Hong, Peng Lin, Weifu Chen, Zhong Zhu, Haixiao Chen

Pages: 547-552 Published online on: 31 May 2017
Open Access

Identification of critical genes in nucleus pulposus cells isolated from degenerated intervertebral discs using bioinformatics analysis

Zhuangchen Zhu, Guang Chen, Wei Jiao, Defeng Wang, Yan Cao, Qingfu Zhang, Junqin Wang

Pages: 553-564 Published online on: 31 May 2017
Open Access

Enhanced effect of nuclear localization signal peptide during ultrasound‑targeted microbubble destruction‑mediated gene transfection

Sheng Cao, Qing Zhou, Jin‑Ling Chen, Nan Jiang, Yi‑Jia Wang, Qing Deng, Bo Hu, Rui‑Qiang Guo

Pages: 565-572 Published online on: 31 May 2017
Open Access

Investigation of the major cytochrome P450 1A2 genetic variant in a healthy Tibetan population in China

Yongchao Ren, Fang Liu, Xugang Shi, Tingting Geng, Dongya Yuan, Li Wang, Longli Kang, Tianbo Jin, Chao Chen

Pages: 573-580 Published online on: 29 May 2017
Open Access

MicroRNA expression analysis during FK506-induced osteogenic differentiation in rat bone marrow stromal cells

Jing Zhang, Xiaoping Yu, Youcheng Yu, Yiming Gong

Pages: 581-590 Published online on: 31 May 2017
Open Access

The expression of DNA methyltransferases3A is specifically downregulated in chorionic villi of early embryo growth arrest cases

Huating Gu, Jing Gao, Weiwei Guo, Yu Zhou, Qingnuan Kong

Pages: 591-596 Published online on: 30 May 2017
Open Access

Nrf2 mediates the protective effects of homocysteine by increasing the levels of GSH content in HepG2 cells

Bing Zhang, Jing‑Lin Dong, Ying‑Li Chen, Yang Liu, Shi‑Shun Huang, Xiu‑Li Zhong, Yu‑Hong Cheng, Zhi‑Gang Wang

Pages: 597-602 Published online on: 25 May 2017
Open Access

Microglia activation triggers oligodendrocyte precursor cells apoptosis via HSP60

Yunhong Li, Rui Zhang, Xiaolin Hou, Yumei Zhang, Feijia Ding, Fan Li, Yao Yao, Yin Wang

Pages: 603-608 Published online on: 01 June 2017
Open Access

Bioinformatics analyses of the differences between lung adenocarcinoma and squamous cell carcinoma using The Cancer Genome Atlas expression data

Fenghao Sun, Xiaodong Yang, Yulin Jin, Li Chen, Lin Wang, Mengkun Shi, Cheng Zhan, Yu Shi, Qun Wang

Pages: 609-616 Published online on: 25 May 2017
Open Access

σ-1 receptor stimulation protects against pressure-induced damage through InsR-MAPK signaling in human trabecular meshwork cells

Bo Meng, Hongyi Li, Xian Sun, Wei Qu, Binbin Yang, Fang Cheng, Liping Shi, Huiping Yuan

Pages: 617-624 Published online on: 30 May 2017
Open Access

A nanobody targeting carcinoembryonic antigen as a promising molecular probe for non-small cell lung cancer

Hao Wang, Ai‑Min Meng, Sheng‑Hua Li, Xiao‑Liang Zhou

Pages: 625-630 Published online on: 01 June 2017
Open Access

Toxic proteins from Croton tiglium L. exert a proinflammatory effect by inducing release of proinflammatory cytokines and activating the p38-MAPK signaling pathway

Liping Liu, Hongli Yu, Hao Wu, Xiaolin Yang, Yaozong Pan, Yeqing Chen, Kuilong Wang, Wei Wang, Wenying Zhang, Yangping Jin, Chengchao Zhang, Ai Jiang, Chunyan Xia

Pages: 631-638 Published online on: 24 May 2017
Open Access

Prostaglandin E2 promotes human CD34+ cells homing through EP2 and EP4 in vitro

Yaqun Wang, Shuping Lai, Jing Tang, Chun Feng, Fangjie Liu, Chang Su, Waiyi Zou, Huizhen Chen, Duorong Xu

Pages: 639-646 Published online on: 30 May 2017
Open Access

Modified citrus pectin inhibits galectin-3 function to reduce atherosclerotic lesions in apoE-deficient mice

Yonggang Lu, Mingming Zhang, Pei Zhao, Min Jia, Bing Liu, Qian Jia, Jun Guo, Lin Dou, Jian Li

Pages: 647-653 Published online on: 29 May 2017
Open Access

Transient cerebral ischemia induces albumin expression in microglia only in the CA1 region of the gerbil hippocampus

Joon Ha Park, Jin‑A Park, Ji Hyeon Ahn, Yang Hee Kim, Il Jun Kang, Moo‑Ho Won, Choong‑Hyun Lee

Pages: 661-665 Published online on: 31 May 2017
Open Access

Tensile strength suppresses the osteogenesis of periodontal ligament cells in inflammatory microenvironments

Chaofan Sun, Fen Liu, Shendan Cen, Lijiao Chen, Yi Wang, Hao Sun, Hui Deng, Rongdang Hu

Pages: 666-672 Published online on: 29 May 2017
Open Access

Farnesoid X receptor deletion improves cardiac function, structure and remodeling following myocardial infarction in mice

Jianshu Gao, Xiaoqiang Liu, Bingjian Wang, Haiyan Xu, Qiang Xia, Tianfei Lu, Fang Wang

Pages: 673-679 Published online on: 29 May 2017
Open Access

Metformin ameliorates hepatic steatosis and improves the induction of autophagy in HFD‑induced obese mice

Min Li, Antara Sharma, Chunyan Yin, Xinrui Tan, Yanfeng Xiao

Pages: 680-686 Published online on: 26 May 2017
Open Access

Differential expression of miRNAs in Osborne's ligament of cubital tunnel syndrome

Xian‑Hu Zhou, Yi‑Ming Ren, Zhi‑Jian Wei, Wei Lin, Bao‑You Fan, Shen Liu, Yan Hao, Gui‑Dong Shi, Shi‑Qing Feng

Pages: 687-695 Published online on: 31 May 2017
Open Access

Revealing radiotherapy- and chemoradiation-induced pathway dynamics in glioblastoma by analyzing multiple differential networks

Jia Zhou, Chao Chen, Hua‑Feng Li, Yu‑Jie Hu, Hong‑Ling Xie

Pages: 696-702 Published online on: 29 May 2017
Open Access

Effects of the Tangningtongluo formula as an alternative strategy for diabetics via upregulation of insulin receptor substrate-1

Long Cheng, Junmei Song, Geng Li, Yue Liu, Yuming Wang, Xiangbao Meng, Guibo Sun, Xiaobo Sun

Pages: 703-709 Published online on: 01 June 2017
Open Access

A novel missense mutation in the ALPL gene causes dysfunction of the protein

Bin Chen, Lili Li, Weitong Ren, Long Yi, Yaping Wang, Fuhua Yan

Pages: 710-718 Published online on: 31 May 2017
Open Access

Multiple Nav1.5 isoforms are functionally expressed in the brain and present distinct expression patterns compared with cardiac Nav1.5

Jun Wang, Shao‑Wu Ou, Yun‑Fei Bai, Yun‑Jie Wang, Zhi‑Qing David Xu, Guo‑Ming Luan

Pages: 719-729 Published online on: 30 May 2017
Open Access

The inhibition of NOTCH2 reduces UVB-induced damage in retinal pigment epithelium cells

Lanying Liu, Xin Zhou, Xielan Kuang, Chongde Long, Weiwei Liu, Yan Tang, Huijun Liu, Jia He, Zixin Huang, Yuting Fan, Qingjiong Zhang, Huangxuan Shen

Pages: 730-736 Published online on: 25 May 2017
Open Access

Anti‑fibrotic effect of Sedum sarmentosum Bunge extract in kidneys via the hedgehog signaling pathway

Yongheng Bai, Cunzao Wu, Weilong Hong, Xing Zhang, Leping Liu, Bicheng Chen

Pages: 737-745 Published online on: 25 May 2017
Open Access

MicroRNA-146a promotes gastric cancer cell apoptosis by targeting transforming growth factor β-activated kinase 1

Yiming Chen, Bin Zhou, Lubai Xu, Hengwei Fan, Junqin Xie, Dan Wang

Pages: 755-763 Published online on: 29 May 2017
Open Access

HSVtk/GCV system on hepatoma carcinoma cells: Construction of the plasmid pcDNA3.1‑pAFP-TK and targeted killing effect

Yong‑Fang Li, Yang‑Yang Yuan, Ying‑Min Zhang, Na Zhao, Qi Zhang, Fan‑Xiu Meng, Ran‑Peng Gao, Bao‑Feng Yu, Yue‑Hong Zhang, Rui Guo, Hai‑Long Wang, Jun Xie, Jun Xu, Qin Qin, Xiu‑Shan Dong

Pages: 764-772 Published online on: 31 May 2017
Open Access

A novel approach to select differential pathways associated with hypertrophic cardiomyopathy based on gene co‑expression analysis

Xiao‑Min Chen, Ming‑Jun Feng, Cai‑Jie Shen, Bin He, Xian‑Feng Du, Yi‑Bo Yu, Jing Liu, Hui‑Min Chu

Pages: 773-777 Published online on: 31 May 2017
Open Access

Upregulation of SOCS3 in lung CD4+ T cells in a mouse model of chronic PA lung infection and suppression of Th17‑mediated neutrophil recruitment in exogenous SOCS3 transfer in vitro

Feng‑Ming Ding, Ruo‑Min Liao, Yu‑Qing Chen, Guo‑Gang Xie, Peng‑Yu Zhang, Ping Shao, Min Zhang

Pages: 778-786 Published online on: 25 May 2017
Open Access

Inhibition of IGF-1 receptor kinase blocks the differentiation into cardiomyocyte-like cells of BMSCs induced by IGF-1

Haibin Gong, Xiuli Wang, Lei Wang, Ying Liu, Jie Wang, Qian Lv, Hui Pang, Qinglin Zhang, Zhenquan Wang

Pages: 787-793 Published online on: 26 May 2017
Open Access

Elemene inhibits the migration and invasion of 4T1 murine breast cancer cells via heparanase

Yi Zhang, Xu Sun, Nan Nan, Ke‑Xin Cao, Cong Ma, Guo‑Wang Yang, Ming‑Wei Yu, Lin Yang, Jin‑Ping Li, Xiao‑Min Wang, Gan‑Lin Zhang

Pages: 794-800 Published online on: 26 May 2017
Open Access

Differences in molecular regulation between osteochondroma and bizarre parosteal osteochondromatous proliferation

Xinrong Zhou, Lihui Deng, Xinsheng Han, Yi Chen, Jiao Wang, Shengnan Du

Pages: 801-805 Published online on: 25 May 2017
Open Access

Prognostic value of PAX9 in patients with esophageal squamous cell carcinoma and its prediction value to radiation sensitivity

Bingxu Tan, Jianbo Wang, Qingxu Song, Nana Wang, Yibin Jia, Cong Wang, Bin Yao, Zhulong Liu, Xiaomei Zhang, Yufeng Cheng

Pages: 806-816 Published online on: 25 May 2017
Open Access

Atheroprotective effects of statins in patients with unstable angina by regulating the blood-borne microRNA network

Sufang Li, Chengfu Cao, Hong Chen, Junxian Song, Chongyou Lee, Jing Zhang, Feng Zhang, Qiang Geng, Zheng Li, Jingjin Li

Pages: 817-827 Published online on: 24 May 2017

Altered expression of epithelial mesenchymal transition and pluripotent associated markers by sex steroid hormones in human embryonic stem cells

So‑Ye Jeon, Kyung‑A Hwang, Cho‑Won Kim, Eui‑Bae Jeung, Kyung‑Chul Choi

Pages: 828-836 Published online on: 31 May 2017

MicroRNA-526a targets p21-activated kinase 7 to inhibit tumorigenesis in hepatocellular carcinoma

Lei Zhan, Yaozhen Pan, Ling Chen, Zili Chen, Hong Zhang, Chengyi Sun

Pages: 837-844 Published online on: 31 May 2017

Underlying mechanism of Sirt1 on apoptosis and extracellular matrix degradation of osteoarthritis chondrocytes

Dong‑Sheng He, Xiao‑Jian Hu, Yi‑Qi Yan, Hui Liu

Pages: 845-850 Published online on: 31 May 2017

Immunogenicity and immunoreactivity of Tp0821 recombinant protein from Treponema pallidum

Ning Wu, Ni Li, Liping Hu, Jun He, Junhong Li, Feijun Zhao, Yimou Wu

Pages: 851-856 Published online on: 01 June 2017

Araliasaponin II isolated from leaves of Acanthopanax henryi (Oliv.) Harms inhibits inflammation by modulating the expression of inflammatory markers in murine macrophages

Yun‑Soo Seo, Seok‑Jeon Lee, Zhi Li, Ok‑Hwa Kang, Ryong Kong, Sang‑A Kim, Tian Zhou, Yung‑Sun Song, Xiangqian Liu, Dong‑Yeul Kwon

Pages: 857-864 Published online on: 31 May 2017

Effects of interleukin-17 on human retinal vascular endothelial cell capillary tube formation in vitro

Gaoqin Liu, Hongya Wu, Lei Chen, Jing Xu, Mengjiao Wang, Dan Li, Peirong Lu

Pages: 865-872 Published online on: 25 May 2017

Genistein and menaquinone-4 treatment-induced alterations in the expression of mRNAs and their products are beneficial to osteoblastic MC3T3-E1 cell functions

Midori Katsuyama, Masashi Demura, Hironobu Katsuyama, Hideji Tanii, Kiyofumi Saijoh

Pages: 873-880 Published online on: 25 May 2017

Altered gene expression of hepatic cytochrome P450 in a rat model of intermittent hypoxia with emphysema

Hongzhi Yu, Hongxia Shao, Qi Wu, Xin Sun, Li Li, Kuan Li, Xue Li, Yu Li, Qiuyang Zhang, Junping Wu, Huaiyong Chen

Pages: 881-886 Published online on: 29 May 2017

Increased SLC7A8 expression mediates L-DOPA uptake by renal tubular epithelial cells

Yihao Wu, Qiqi Yin, Su Lin, Xiaoyan Huang, Quan Xia, Zhe Chen, Xingwei Zhang, Deye Yang

Pages: 887-893 Published online on: 25 May 2017

An FGF8b-mimicking peptide with potent antiangiogenic activity

Xiaomian Lin, Li Song, Dan He, Xiangfeng Zeng, Jianzhang Wu, Wu Luo, Qi Yang, Jizhong Wang, Tianxiang Wang, Jialong Cai, Yanling Lin, Fubin Lai, Wentao Peng, Xiaoping Wu

Pages: 894-900 Published online on: 30 May 2017

CpG methylation patterns are associated with gene expression variation in osteosarcoma

Qiang Wang

Pages: 901-907 Published online on: 26 May 2017

VPA and MEL induce apoptosis by inhibiting the Nrf2-ARE signaling pathway in TMZ-resistant U251 cells

Hao Pan, Handong Wang, Yue Jia, Qiang Wang, Liwen Li, Qi Wu, Longbang Chen

Pages: 908-914 Published online on: 25 May 2017

Noninvasive detection of acute renal allograft rejection by measurement of soluble Tim-3 in urine

Dajin Chen, Wenhan Peng, Hong Jiang, Hao Yang, Jianyong Wu, Huiping Wang, Jianghua Chen

Pages: 915-921 Published online on: 31 May 2017

Rutaecarpine alleviates renal ischemia reperfusion injury in rats by suppressing the JNK/p38 MAPK signaling pathway and interfering with the oxidative stress response

Chunhua Wang, Zongyao Hao, Jun Zhou, Li Zhang, Yexiang Sun, Chaozhao Liang

Pages: 922-928 Published online on: 25 May 2017

Overexpression of GLP-1 receptors suppresses proliferation and cytokine release by airway smooth muscle cells of patients with chronic obstructive pulmonary disease via activation of ABCA1

Yan‑Hong Sun, Lan He, Ming‑Yu Yan, Rui‑Qian Zhao, Bin Li, Feng Wang, Ying Yang, Hua‑Peng Yu

Pages: 929-936 Published online on: 25 May 2017

Lymphotoxin β receptor activation promotes mRNA expression of RelA and pro-inflammatory cytokines TNFα and IL-1β in bladder cancer cells

Mo Shen, Lianlian Zhou, Ping Zhou, Wu Zhou, Xiangyang Lin

Pages: 937-942 Published online on: 01 June 2017

Inhibitory capacity of Rhus coriaria L. extract and its major component methyl gallate on Streptococcus mutans biofilm formation by optical profilometry: Potential applications for oral health

Tomas Kacergius, Saleh Abu‑Lafi, Agne Kirkliauskiene, Vika Gabe, Azmi Adawi, Mahmoud Rayan, Mutaz Qutob, Rimantas Stukas, Algirdas Utkus, Mouhammad Zeidan, Anwar Rayan

Pages: 949-956 Published online on: 01 June 2017

The restraining effect of baicalein and U0126 on human cervical cancer cell line HeLa

Haiqiong Ye, Yujiao Zhang, Yongzhou Wang, Jiyi Xia, Xiguang Mao, Xiaolan Yu

Pages: 957-963 Published online on: 30 May 2017

Hypomethylation of the Toll-like receptor-2 gene increases the risk of essential hypertension

Shuqi Mao, Tianlun Gu, Fade Zhong, Rui Fan, Fubao Zhu, Peipei Ren, Fengying Yin, Lina Zhang

Pages: 964-970 Published online on: 30 May 2017

Hydrogen sulfide inhibits mitochondrial fission in neuroblastoma N2a cells through the Drp1/ERK1/2 signaling pathway

Peifeng Qiao, Fengli Zhao, Mengjie Liu, Dan Gao, Hua Zhang, Yong Yan

Pages: 971-977 Published online on: 25 May 2017

Apoptosis is induced by docosahexaenoic acid in breast cancer cells via death receptor and mitochondria-mediated pathways

Meilan Xue, Yinlin Ge, Chundong Yu, Zheng Zheng, Xinjia He, Jinglan Zhao

Pages: 978-982 Published online on: 01 June 2017
Journal Cover

July 2017
Volume 16 Issue 1

Print ISSN: 1791-2997
Online ISSN: 1791-3004

2016 Impact Factor: 1.692
Ranked #19/128 Medicine Research and Experimental
(total number of cites)

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