Journal Articles

Open Access

Notch signaling in cerebrovascular diseases (Review)

Zhiyou Cai, Bin Zhao, Yanqing Deng, Shouqin Shangguan, Faming Zhou, Wenqing Zhou, Xiaoli Li, Yanfeng Li, Guanghui Chen

Pages: 2883-2898 Published online on: 19 August 2016
Open Access

Endocannabinoid system: Role in depression, reward and pain control (Review)

Wen‑Juan Huang, Wei‑Wei Chen, Xia Zhang

Pages: 2899-2903 Published online on: 01 August 2016
Open Access

Silencing of TBX20 gene expression in rat myocardial and human embryonic kidney cells leads to cell cycle arrest in G2 phase

Peiyan Liu, Yueling Sun, Guangbin Qiu, Hongkun Jiang, Guangrong Qiu

Pages: 2904-2914 Published online on: 19 August 2016
Open Access

A novel variant of androgen receptor is associated with idiopathic azoospermia

Lisha Mou, Yaoting Gui

Pages: 2915-2920 Published online on: 04 August 2016
Open Access

Inhibitory effect of metformin combined with gemcitabine on pancreatic cancer cells in vitro and in vivo

Yuqi Shi, Zhilong He, Zhenyu Jia, Chunfang Xu

Pages: 2921-2928 Published online on: 04 August 2016
Open Access

Sonic hedgehog protein regulates fibroblast growth factor 8 expression in metanephric explant culture from BALB/c mice: Possible mechanisms associated with renal morphogenesis

Xing Chen, Xiao‑Ming Hou, You‑Fei Fan, Yu‑Ting Jin, Yu‑Lin Wang

Pages: 2929-2936 Published online on: 09 August 2016
Open Access

Anti-wrinkle effects of Sargassum muticum ethyl acetate fraction on ultraviolet B-irradiated hairless mouse skin and mechanistic evaluation in the human HaCaT keratinocyte cell line

Jae Hyoung Song, Mei Jing Piao, Xia Han, Kyoung Ah Kang, Hee Kyoung Kang, Weon Jong Yoon, Mi Hee Ko, Nam Ho Lee, Mi Young Lee, Sungwook Chae, Jin Won Hyun

Pages: 2937-2944 Published online on: 19 August 2016
Open Access

Rspo2 suppresses CD36-mediated apoptosis in oxidized low density lipoprotein-induced macrophages

Hui Yan, Shuai Wang, Zhenwei Li, Zewei Sun, Jie Zan, Wenting Zhao, Yanyun Pan, Zhen Wang, Mingjie Wu, Jianhua Zhu

Pages: 2945-2952 Published online on: 19 August 2016
Open Access

Lycopene inhibits the cell proliferation and invasion of human head and neck squamous cell carcinoma

Min Ye, Qundan Wu, Min Zhang, Jinbei Huang

Pages: 2953-2958 Published online on: 08 August 2016
Open Access

A technical application of quantitative next generation sequencing for chimerism evaluation

Michelangelo Aloisio, Danilo Licastro, Luciana Caenazzo, Valentina Torboli, Angela D'Eustacchio, Giovanni Maria Severini, Emmanouil Athanasakis

Pages: 2967-2974 Published online on: 04 August 2016
Open Access

miRNA-411 acts as a potential tumor suppressor miRNA via the downregulation of specificity protein 1 in breast cancer

Liangfeng Guo, Jianhui Yuan, Ni Xie, Huisheng Wu, Weicai Chen, Shufen Song, Xianming Wang

Pages: 2975-2982 Published online on: 19 August 2016
Open Access

Toll‑like receptor 4 contributes to acute kidney injury after cardiopulmonary resuscitation in mice

Qingsong Zhang, Gang Li, Li Xu, Qian Li, Qianyan Wang, Yue Zhang, Qing Zhang, Peng Sun

Pages: 2983-2990 Published online on: 08 August 2016
Open Access

Investigation of the association between miR‑181b, Bcl‑2 and LRIG1 in oral verrucous carcinoma

Zhi‑Yuan Deng, Yue‑Hong Wang, Hong‑Zhi Quan, Ou‑Sheng Liu, Yi‑Ping Li, Yuan Li, Wu Zhu, Krishna Munnee, Zhan‑Gui Tang

Pages: 2991-2996 Published online on: 09 August 2016
Open Access

FSH aggravates bone loss in ovariectomised rats with experimental periapical periodontitis

Hua Qian, Xiaoyue Guan, Zhuan Bian

Pages: 2997-3006 Published online on: 09 August 2016
Open Access

Quantum dot-based molecular imaging of cancer cell growth using a clone formation assay

Xia‑Fei Geng, Min Fang, Shao‑Ping Liu, Yan Li

Pages: 3007-3012 Published online on: 18 August 2016
Open Access

Cabazitaxel-induced autophagy via the PI3K/Akt/mTOR pathway contributes to A549 cell death

Ruichao Huo, Lili Wang, Peijuan Liu, Yong Zhao, Caiqin Zhang, Bing Bai, Xueying Liu, Changhong Shi, Sanhua Wei, Hai Zhang

Pages: 3013-3020 Published online on: 19 August 2016
Open Access

MicroRNA-588 suppresses tumor cell migration and invasion by targeting GRN in lung squamous cell carcinoma

Li Qian, Longlong Lin, Yufeng Du, Xiaoyan Hao, Yuze Zhao, Xuejun Liu

Pages: 3021-3028 Published online on: 19 August 2016
Open Access

Dehydrocorydaline promotes myogenic differentiation via p38 MAPK activation

Miran Yoo, Sang‑Jin Lee, Yong Kee Kim, Dong‑Wan Seo, Nam‑In Baek, Jae‑Ha Ryu, Jong‑Sun Kang, Gyu‑Un Bae

Pages: 3029-3036 Published online on: 19 August 2016
Open Access

Effect of autophagy induced by dexamethasone on senescence in chondrocytes

Enxing Xue, Yu Zhang, Bing Song, Jun Xiao, Zhanjun Shi

Pages: 3037-3044 Published online on: 22 August 2016
Open Access

Human tonsil‑derived mesenchymal stromal cells enhanced myelopoiesis in a mouse model of allogeneic bone marrow transplantation

Jung‑Hwa Ryu, Minhwa Park, Bo‑Kyung Kim, Yu‑Hee Kim, So‑Youn Woo, Kyung‑Ha Ryu

Pages: 3045-3051 Published online on: 08 August 2016
Open Access

Analysis of gene expression profile identifies potential biomarkers for atherosclerosis

Luran Liu, Yan Liu, Chang Liu, Zhuobo Zhang, Yaojun Du, Hao Zhao

Pages: 3052-3058 Published online on: 19 August 2016
Open Access

Overexpression of gelsolin reduces the proliferation and invasion of colon carcinoma cells

Wen‑Xiang Li, Meng‑Xuan Yang, Xin‑Qiang Hong, Tian‑Geng Dong, Tuo Yi, Sheng‑Li Lin, Xin‑Yu Qin, Wei‑Xin Niu

Pages: 3059-3065 Published online on: 19 August 2016
Open Access

Possible role of the Ec peptide of IGF‑1Ec in cartilage repair

Nikolaos Armakolas, Andreas Dimakakos, Athanasios Armakolas, Athanasios Antonopoulos, Michael Koutsilieris

Pages: 3066-3072 Published online on: 12 August 2016
Open Access

Impact of quercetin‑induced changes in drug‑metabolizing enzyme and transporter expression on the pharmacokinetics of cyclosporine in rats

Yani Liu, Xiaomei Luo, Chunxiao Yang, Tingyu Yang, Jiali Zhou, Shaojun Shi

Pages: 3073-3085 Published online on: 09 August 2016
Open Access

Allicin protects traumatic spinal cord injury through regulating the HSP70/Akt/iNOS pathway in mice

Shunyi Wang, Dongliang Ren

Pages: 3086-3092 Published online on: 19 August 2016
Open Access

Solanum tuberosum L. cv Hongyoung extract inhibits 2,4‑dinitrochlorobenzene‑induced atopic dermatitis in NC/Nga mice

Myung Ah Kang, Se‑Young Choung

Pages: 3093-3103 Published online on: 08 August 2016
Open Access

Mesenchymal stem cells in corneal neovascularization: Comparison of different application routes

Emma Ghazaryan, Yan Zhang, Yuxi He, Xin Liu, Ying Li, Jianan Xie, Guanfang Su

Pages: 3104-3112 Published online on: 11 August 2016
Open Access

The study on mechanism of the modified Chinese herbal compound, jianpijiedu, on a mouse model of hepatic carcinoma cachexia

Baoguo Sun, Haoxuan Luo, Liuxiang Deng, Shijun Zhang, Zexiong Chen

Pages: 3113-3121 Published online on: 08 August 2016
Open Access

Atorvastatin attenuates p‑cresyl sulfate‑induced atherogenesis and plaque instability in ApoE knockout mice

Hui Han, Yanjia Chen, Jinzhou Zhu, Jingwei Ni, Jiateng Sun, Ruiyan Zhang

Pages: 3122-3128 Published online on: 12 August 2016
Open Access

A novel missense mutation of the GRK1 gene in Oguchi disease

Mehmet Yasin Teke, Mehmet Citirik, Serkan Kabacam, Suleyman Demircan, Mehmet Alikasifoglu

Pages: 3129-3133 Published online on: 09 August 2016
Open Access

Reprogramming A375 cells to induced‑resembled neuronal cells by structured overexpression of specific transcription genes

Hengzhu Zhang, Min Wei, Yangyang Jiang, Xiaodong Wang, Lei She, Zhengcun Yan, Lun Dong, Lujun Pang, Xingdong Wang

Pages: 3134-3144 Published online on: 08 August 2016
Open Access

KIF21A mutation in two Chinese families with congenital fibrosis of the extraocular muscles type 1 and 3

Jingchang Chen, Qingqing Ye, Daming Deng, Jianhua Yan, Houbian Lin, Tao Shen, Ying Lin

Pages: 3145-3151 Published online on: 11 August 2016
Open Access

Hypolipidemic effects of HVC1 in a high cholesterol diet‑induced rat model of hyperlipidemia

Chae‑Yun Kim, Kyung‑Sook Chung, Se‑Yun Cheon, Kyungjin Lee, Inhye Ham, Ho‑Young Choi, Yong Baik Cho, Byoung‑Heon Cho, So Youn Mok, Hyo‑Jin An

Pages: 3152-3158 Published online on: 09 August 2016
Open Access

Overexpression of CD44 is associated with the occurrence and migration of non-small cell lung cancer

Guanghu Li, Yufei Gao, Yongsheng Cui, Tao Zhang, Rui Cui, Yang Jiang, Jingwei Shi

Pages: 3159-3167 Published online on: 18 August 2016
Open Access

Identification of distinct genes associated with seawater aspiration‑induced acute lung injury by gene expression profile analysis

Wei Liu, Lei Pan, Minlong Zhang, Liyan Bo, Congcong Li, Qingqing Liu, Li Wang, Faguang Jin

Pages: 3168-3178 Published online on: 09 August 2016
Open Access

Natural compound oblongifolin C inhibits autophagic flux, and induces apoptosis and mitochondrial dysfunction in human cholangiocarcinoma QBC939 cells

Aiqing Zhang, Wei He, Huimin Shi, Xiaodan Huang, Guozhong Ji

Pages: 3179-3183 Published online on: 04 August 2016
Open Access

Potential fluid biomarkers for pathological brain changes in Alzheimer's disease: Implication for the screening of cognitive frailty

Qingwei Ruan, Grazia D'Onofrio, Daniele Sancarlo, Antonio Greco, Zhuowei Yu

Pages: 3184-3198 Published online on: 09 August 2016
Open Access

Paris saponin VII suppresses osteosarcoma cell migration and invasion by inhibiting MMP‑2/9 production via the p38 MAPK signaling pathway

Gong Cheng, Fengguang Gao, Xiujiang Sun, Haiyong Bi, Yonglin Zhu

Pages: 3199-3205 Published online on: 22 August 2016
Open Access

Ameliorative effects of Artemisia argyi Folium extract on 2,4‑dinitrochlorobenzene‑induced atopic dermatitis‑like lesions in BALB/c mice

Hyoung‑Min Han, Seung‑Ju Kim, Jong‑Sik Kim, Bum Hoi Kim, Hai Woong Lee, Yong Tae Lee, Kyung‑Hwa Kang

Pages: 3206-3214 Published online on: 19 August 2016
Open Access

Age‑dependent increase in the expression of antioxidant‑like protein‑1 in the gerbil hippocampus

Jin‑A Park, Joon Ha Park, Ji Hyeon Ahn, Jong‑Dai Kim, Moo‑Ho Won, Choong‑Hyun Lee

Pages: 3215-3219 Published online on: 09 August 2016
Open Access

Epidermal growth factor receptor kinase substrate 8 promotes the metastasis of cervical cancer via the epithelial-mesenchymal transition

Qian Li, Wei Bao, Qiong Fan, Wen‑Jing Shi, Zhu‑Nan Li, Ying Xu, Dan Wu

Pages: 3220-3228 Published online on: 18 August 2016

Curcumin attenuates cyclosporine A‑induced renal fibrosis by inhibiting hypermethylation of the klotho promoter

Ying Hu, Lijun Mou, Fuye Yang, Haiyan Tu, Wanbing Lin

Pages: 3229-3236 Published online on: 08 August 2016

Dose response of dexmedetomidine‑induced resistance to hypoxia in mice

Wanying Pan, Xiaoxiao Hua, Yueting Wang, Ruixian Guo, Jingfu Chen, Liqiu Mo

Pages: 3237-3242 Published online on: 04 August 2016

Traditional Chinese medicine: Pivotal role of the spleen in the metabolism of aristolochic acid I in rats is dependent on oatp2a1

Ting Xiang, Zhangbin Yang, Baoguo Sun, Haoxuan Luo, Shijun Zhang, Bin Ren, Xiaoling Chen, Xin Zhou, Zexiong Chen

Pages: 3243-3250 Published online on: 09 August 2016

Molecular genetic analysis and phenotypic characteristics of a consanguineous family with glycogen storage disease type Ia

Yili Lu, Liyin Wang, Jun Li, Beibei Wu, Huiping Wu, Yue Luo, Zi‑Bing Jin, Xiaoou Shan

Pages: 3251-3254 Published online on: 09 August 2016

HOXC6 promotes gastric cancer cell invasion by upregulating the expression of MMP9

Shi‑Wei Chen, Qing Zhang, Zhi‑Feng Xu, Hai‑Ping Wang, Yi Shi, Feng Xu, Wen‑Jian Zhang, Ping Wang, Yong Li

Pages: 3261-3268 Published online on: 19 August 2016

Characterization of multidrug‑resistant osteosarcoma sublines and the molecular mechanisms of resistance

Jian‑Zeng Yang, Shu‑Rong Ma, Xiao‑Li Rong, Mei‑Ju Zhu, Qiu‑Ye Ji, Ling‑Jie Meng, Yi‑Yao Gao, Yu‑Dan Yang, Yan Wang

Pages: 3269-3276 Published online on: 04 August 2016

Jatrorrhizine hydrochloride attenuates hyperlipidemia in a high-fat diet-induced obesity mouse model

Weiwei Yang, Liping She, Kun Yu, Shan Yan, Xuefeng Zhang, Xiaoyi Tian, Shuren Ma, Xiwen Zhang

Pages: 3277-3284 Published online on: 18 August 2016

Let‑7 miRNAs sensitize breast cancer stem cells to radiation‑induced repression through inhibition of the cyclin D1/Akt1/Wnt1 signaling pathway

Huifang Sun, Changmao Ding, Huiyu Zhang, Jianbo Gao

Pages: 3285-3292 Published online on: 19 August 2016

Angiopoietin-like protein 4 improves glucose tolerance and insulin resistance but induces liver steatosis in high-fat-diet mice

Yi Wang, Li‑Ming Liu, Li Wei, Wei‑Wei Ye, Xiang‑Ying Meng, Feng Chen, Qian Xiao, Jian‑Yang Chen, Yong Zhou

Pages: 3293-3300 Published online on: 18 August 2016

Sphingomyelin synthase 2 affects CD14‑associated induction of NF‑κB by lipopolysaccharides in acute lung injury in mice

Shidong Hu, Yi Ding, Jie Gong, Nianlong Yan

Pages: 3301-3306 Published online on: 09 August 2016

A novel TBX20 loss‑of‑function mutation contributes to adult‑onset dilated cardiomyopathy or congenital atrial septal defect

Yi‑Meng Zhou, Xiao‑Yong Dai, Ri‑Tai Huang, Song Xue, Ying‑Jia Xu, Xing‑Biao Qiu, Yi‑Qing Yang

Pages: 3307-3314 Published online on: 09 August 2016

Correlation between low tapasin expression and impaired CD8+ T‑cell function in patients with chronic hepatitis B

Yuyan Tang, Jieling Wang, Yi Zhang, Meng Zhuo, Linlin Song, Zhenghao Tang, Guoqing Zang, Xiaohua Chen, Yongsheng Yu

Pages: 3315-3322 Published online on: 09 August 2016

Inflammation has a role in urethane‑induced lung cancer in C57BL/6J mice

Cai Xu, Lingyu Zhou, Lei Lu, Ting Chen, Siyu Wei, Xiaojing Lin, Xuemei Lian

Pages: 3323-3328 Published online on: 19 August 2016

TRIF is a regulator of TLR2-induced foam cell formation

Bin Huang, Dae‑Weon Park, Suk‑Hwan Baek

Pages: 3329-3335 Published online on: 19 August 2016

Distribution of fibroblast growth factors and their roles in skin fibroblast cell migration

Yong Huan Song, Yu Ting Zhu, Jian Ding, Fei Ya Zhou, Ji Xin Xue, Jin Hee Jung, Zhi Jie Li, Wei Yang Gao

Pages: 3336-3342 Published online on: 19 August 2016

miR‑205 suppresses cell proliferation, invasion, and metastasis via regulation of the PTEN/AKT pathway in renal cell carcinoma

Huiqiang Wang, Bin Chen, Bo Duan, Jiaxin Zheng, Xinyi Wu

Pages: 3343-3349 Published online on: 04 August 2016

Identification of microRNA profiles associated with refractory primary biliary cirrhosis

Teppei Sakamoto, Asahiro Morishita, Takako Nomura, Joji Tani, Hisaaki Miyoshi, Hirohiro Yoneyama, Hisakazu Iwama, Takashi Himoto, Tsutomu Masaki

Pages: 3350-3356 Published online on: 09 August 2016

PRDM16 is associated with evasion of apoptosis by prostatic cancer cells according to RNA interference screening

Shaoxing Zhu, Yipeng Xu, Mei Song, Guiping Chen, Hua Wang, Yang Zhao, Zongping Wang, Fangyin Li

Pages: 3357-3361 Published online on: 08 August 2016

Distal hereditary motor neuropathy type 7B with Dynactin 1 mutation

Sun Hee Hwang, Eun Ja Kim, Young Bin Hong, Jaesoon Joo, Sung Min Kim, Soo Hyun Nam, Hyun Dae Hong, Seung Hyun Kim, Kiwook Oh, Jeong‑Geun Lim, Jeong Hee Cho, Ki Wha Chung, Byung‑Ok Choi

Pages: 3362-3368 Published online on: 22 August 2016

S1PR1 mediates anti‑apoptotic/pro‑proliferative processes in human acute myeloid leukemia cells

Xiao‑Qian Xu, Chong‑Mei Huang, Yi‑Fan Zhang, Li Chen, Hui Cheng, Jian‑Min Wang

Pages: 3369-3375 Published online on: 12 August 2016

The protective role of p72 in doxorubicin‑induced cardiomyocytes injury in vitro

Bin Lin, Feng Wang, Jiaxiang Wang, Chengyang Xu, Hui Zhao, Zhaoyun Cheng, Deguang Feng

Pages: 3376-3380 Published online on: 08 August 2016

Lycorine protects cartilage through suppressing the expression of matrix metalloprotenases in rat chondrocytes and in a mouse osteoarthritis model

Shuai Chen, Xiang‑Qian Fang, Jian‑Feng Zhang, Yan Ma, Xiao‑Zhen Tang, Zhi‑Jie Zhou, Ji‑Ying Wang, An Qin, Shun‑Wu Fan

Pages: 3389-3396 Published online on: 08 August 2016

Renoprotective effects of ursolic acid on ischemia/reperfusion‑induced acute kidney injury through oxidative stress, inflammation and the inhibition of STAT3 and NF‑κB activities

Jun Peng, Xingfeng Ren, Tianbiao Lan, Yan Chen, Ziyun Shao, Cheng Yang

Pages: 3397-3402 Published online on: 19 August 2016

Dexmedetomidine pretreatment attenuates propofol‑induced neurotoxicity in neuronal cultures from the rat hippocampus

Yi Wei, Junhua Hu, Yubing Liang, Yuling Zhong, Dan He, Yi Qin, Li Li, Jing Chen, Qiang Xiao, Yubo Xie

Pages: 3413-3420 Published online on: 12 August 2016

miR‑483‑5p promotes growth, invasion and self‑renewal of gastric cancer stem cells by Wnt/β‑catenin signaling

Kai Wu, Longan Ma, Jinxiang Zhu

Pages: 3421-3428 Published online on: 08 August 2016

Collagen regulates transforming growth factor-β receptors of HL-1 cardiomyocytes through activation of stretch and integrin signaling

Yen‑Yu Lu, Yung‑Kuo Lin, Yu‑Hsun Kao, Cheng‑Chih Chung, Yung‑Hsin Yeh, Shih‑Ann Chen, Yi‑Jen Chen

Pages: 3429-3436 Published online on: 18 August 2016

Knockdown of TACC3 inhibits trophoblast cell migration and invasion through the PI3K/Akt signaling pathway

Xiaojun Zhu, Qianqian Cao, Xia Li, Zhengping Wang

Pages: 3437-3442 Published online on: 19 August 2016

Genetic variants in FGFR2 and TNRC9 genes are associated with breast cancer risk in Pakistani women

Ayesha Mazhar, Farrukh Jamil, Qamar Bashir, Munawar Saleem Ahmad, Misbah Masood, Imrana Tanvir, Naeem Rashid, Abdul Waheed, Muhammad Naveed Afzal, Muhammad Akram Tariq

Pages: 3443-3451 Published online on: 18 August 2016

Exosomes derived from human mesenchymal stem cells promote gastric cancer cell growth and migration via the activation of the Akt pathway

Hongbing Gu, Runbi Ji, Xu Zhang, Mei Wang, Wei Zhu, Hui Qian, Yongchang Chen, Pengcheng Jiang, Wenrong Xu

Pages: 3452-3458 Published online on: 11 August 2016

Plasma heme oxygenase-1 is decreased in peripheral artery disease patients

Salvatore Santo Signorelli, Guido Li Volsi, Valerio Fiore, Marco Mangiafico, Ignazio Barbagallo, Rosalba Parenti, Manfredi Rizzo, Giovanni Li Volti

Pages: 3459-3463 Published online on: 19 August 2016

Inhibitory effects of B‑cell translocation gene 2 on skin cancer cells via the Wnt/β‑catenin signaling pathway

Shou‑Song Gao, Xiao‑Hong Yang, Meng Wang

Pages: 3464-3468 Published online on: 08 August 2016

Decitabine enhances bortezomib treatment in RPMI 8226 multiple myeloma cells

Yang Cao, Guo‑Qiang Qiu, Hao‑Qing Wu, Zhi‑Lin Wang, Yan Lin, Wei Wu, Xiao‑Bao Xie, Wei‑Ying Gu

Pages: 3469-3475 Published online on: 19 August 2016

Endogenously synthesized n-3 fatty acids in fat-1 transgenic mice prevent melanoma progression by increasing E-cadherin expression and inhibiting β-catenin signaling

Xuan Yin, Xiong‑Wei Yu, Pan Zhu, Yuan‑Ming Zhang, Xiao‑Hong Zhang, Feng Wang, Jin‑Jie Zhang, Wang Yan, Yang Xi, Jian‑Bo Wan, Jing‑Xuan Kang, Zu‑Quan Zou, Shi‑Zhong Bu

Pages: 3476-3484 Published online on: 18 August 2016

Expression of early and late cellular damage markers by ARPE-19 cells following prolonged treatment with UV-A radiation

Giuseppe Tringali, Beatrice Sampaolese, Maria Elisabetta Clementi

Pages: 3485-3489 Published online on: 19 August 2016
Open Access

Differential activation of c‑Fos in the paraventricular nuclei of the hypothalamus and thalamus following myocardial infarction in rats

Hyun‑Jin Tae, Seung Min Park, Jeong Hwi Cho, In Hye Kim, Ji Hyeon Ahn, Joon Ha Park, Moo‑Ho Won, Bai Hui Chen, Bich‑Na Shin, Myoung Cheol Shin, Choong Hyun Lee, Seongkweon Hong, Jae‑Chul Lee, Jun Hwi Cho

Pages: 3503-3508 Published online on: 07 September 2016
Open Access

Histone deacetylase enzyme silencing using shRNAs enhances radiosensitivity of SW579 thyroid cancer cells

Ye Wang, Tao Jin, Xueming Dai, Dongwang Yan, Zhihai Peng

Pages: 3509-3516 Published online on: 05 September 2016
Open Access

Notch 2 signaling contributes to cell growth, anti-apoptosis and metastasis in laryngeal squamous cell carcinoma

You Zou, Fang Fang, Yong‑Jun Ding, Meng‑Yuan Dai, Xing Yi, Chen Chen, Ze‑Zhang Tao, Shi‑Ming Chen

Pages: 3517-3524 Published online on: 29 August 2016
Open Access

Severity of pancreatitis‑associated intestinal mucosal barrier injury is reduced following treatment with the NADPH oxidase inhibitor apocynin

Wenhong Deng, Ablikim Abliz, Sheng Xu, Rongze Sun, Wenyi Guo, Qiao Shi, Jia Yu, Weixing Wang

Pages: 3525-3534 Published online on: 26 August 2016
Open Access

Apoptosis repressor with caspase recruitment domain enhances survival and promotes osteogenic differentiation of human osteoblast cells under Zoledronate treatment

Longwei Hu, Jing Han, Xi Yang, Yang Wang, Hongya Pan, Liqun Xu

Pages: 3535-3542 Published online on: 24 August 2016
Open Access

ZFAT gene variant association with multiple sclerosis in the Arabian Gulf population: A genetic basis for gender-associated susceptibility

Sonia Bourguiba‑Hachemi, Tebah K. Ashkanani, Fatema J. Kadhem, Wassim Y. Almawi, Raed Alroughani, M. Dahmani Fathallah

Pages: 3543-3550 Published online on: 30 August 2016
Open Access

Frequently rearranged in advanced T‑cell lymphomas‑1 demonstrates oncogenic properties in prostate cancer

Wei Zhang, Hua Xiong, Yanmei Zou, Sanpeng Xu, Lanping Quan, Xianglin Yuan, Ningzhi Xu, Yihua Wang

Pages: 3551-3558 Published online on: 05 September 2016
Open Access

Tormentic acid inhibits H2O2-induced oxidative stress and inflammation in rat vascular smooth muscle cells via inhibition of the NF-κB signaling pathway

Yu‑Lun Wang, Gen‑Yi Sun, Ying Zhang, Jia‑Jun He, Shen Zheng, Jing‑Na Lin

Pages: 3559-3564 Published online on: 30 August 2016
Open Access

Pro‑neurogenic effects of andrographolide on RSC96 Schwann cells in vitro

Fuben Xu, Huayu Wu, Kun Zhang, Peizhen Lv, Li Zheng, Jinmin Zhao

Pages: 3573-3580 Published online on: 06 September 2016
Open Access

Protective effect of active perfusion in porcine models of acute myocardial ischemia

Zanxiang Feng, Zhifu Mao, Shengjun Dong, Baohui Liu

Pages: 3581-3587 Published online on: 24 August 2016
Open Access

Curcumin ameliorates high‑fat diet‑induced spermatogenesis dysfunction

Yang Mu, Wen‑Jie Yan, Tai‑Lang Yin, Jing Yang

Pages: 3588-3594 Published online on: 05 September 2016
Open Access

Impact of siRNA targeting of β-catenin on differentiation of rat neural stem cells and gene expression of Ngn1 and BMP4 following in vitro hypoxic-ischemic brain damage

Xiaoying Zhang, Cuicui Zhu, Qiong Luo, Jv Dong, Lv Liu, Min Li, Hongtao Zhu, Xiangping Ma, Jun Wang

Pages: 3595-3601 Published online on: 24 August 2016
Open Access

Upregulation of retinoic acid receptor-β reverses drug resistance in cholangiocarcinoma cells by enhancing susceptibility to apoptosis

Hong‑Yue Ren, Bo Chen, Gui‑Li Huang, Yu Liu, Dong‑Yan Shen

Pages: 3602-3608 Published online on: 02 September 2016
Open Access

Curcumin inhibits osteoclastogenic potential in PBMCs from rheumatoid arthritis patients via the suppression of MAPK/RANK/c-Fos/NFATc1 signaling pathways

Wei Shang, Ling‑Jie Zhao, Xiao‑Lei Dong, Zhi‑Ming Zhao, Jing Li, Bei‑Bei Zhang, Hui Cai

Pages: 3620-3626 Published online on: 25 August 2016
Open Access

Activated leukocyte cell adhesion molecule regulates the interaction between pancreatic cancer cells and stellate cells

Wei‑Wei Zhang, Shu‑Hui Zhan, Chang‑Xin Geng, Xin Sun, Mert Erkan, Jörg Kleeff, Xiang‑Jun Xie

Pages: 3627-3633 Published online on: 26 August 2016
Open Access

In vitro antitumor activity of the ethyl acetate extract of Potentilla chinensis in osteosarcoma cancer cells

Guang Wan, Jin‑Gang Tao, Guo‑Dong Wang, Shen‑Peng Liu, Hong‑Xing Zhao, Qiu‑Dong Liang

Pages: 3634-3640 Published online on: 26 August 2016
Open Access

A novel KMT2D mutation resulting in Kabuki syndrome: A case report

Jun Lu, Guiling Mo, Yaojun Ling, Lijuan Ji

Pages: 3641-3645 Published online on: 26 August 2016
Open Access

Cytoplasmic translocation of high-mobility group box-1 protein is induced by diabetes and high glucose in retinal pericytes

Junghyun Kim, Chan‑Sik Kim, Eunjin Sohn, Jin Sook Kim

Pages: 3655-3661 Published online on: 02 September 2016
Open Access

Liraglutide attenuates the osteoblastic differentiation of MC3T3‑E1 cells by modulating AMPK/mTOR signaling

Xiong‑Ke Hu, Xin‑Hua Yin, Hong‑Qi Zhang, Chao‑Feng Guo, Ming‑Xing Tang

Pages: 3662-3668 Published online on: 06 September 2016
Open Access

Fibronectin expression is critical for liver fibrogenesis in vivo and in vitro

Xiao‑Ya Liu, Rui‑Xia Liu, Fei Hou, Li‑Jian Cui, Chun-Yun Li, Cheng Chi, Entong Yi, Yan Wen, Cheng‑Hong Yin

Pages: 3669-3675 Published online on: 25 August 2016
Open Access

Expressing human SHOX in Shox2SHOX KI/KI mice leads to congenital osteoarthritis‑like disease of the temporomandibular joint in postnatal mice

Wenna Liang, Xihai Li, Houhuang Chen, Xiang Shao, Xuejuan Lin, Jianying Shen, Shanshan Ding, Jie Kang, Candong Li

Pages: 3676-3682 Published online on: 05 September 2016
Open Access

Resveratrol attenuates acute kidney injury by inhibiting death receptor‑mediated apoptotic pathways in a cisplatin‑induced rat model

Qiufa Hao, Xiaoyan Xiao, Junhui Zhen, Jinbo Feng, Chun Song, Bei Jiang, Zhao Hu

Pages: 3683-3689 Published online on: 05 September 2016
Open Access

Hydroxysafflor yellow A exerts antioxidant effects in a rat model of traumatic brain injury

Yang Wang, Chunhu Zhang, Weijun Peng, Zian Xia, Pingping Gan, Wei Huang, Yafei Shi, Rong Fan

Pages: 3690-3696 Published online on: 06 September 2016
Open Access

Expression of claudins, occludin, junction adhesion molecule A and zona occludens 1 in canine organs

Changhwan Ahn, Da‑Hye Shin, Dongoh Lee, Su‑Myung Kang, Ju‑Hyung Seok, Hee Young Kang, Eui‑Bae Jeung

Pages: 3697-3703 Published online on: 06 September 2016
Open Access

Antiviral activities of atractylon from Atractylodis Rhizoma

Yang Cheng, Jing‑Yin Mai, Tian‑Lu Hou, Jian Ping, Jian‑Jie Chen

Pages: 3704-3710 Published online on: 05 September 2016

Beneficial effects of grape seed proanthocyanidin extract on arterial remodeling in spontaneously hypertensive rats via protecting against oxidative stress

Ying Liang, Jian Wang, Haiqing Gao, Quanzhen Wang, Jun Zhang, Jie Qiu

Pages: 3711-3718 Published online on: 01 September 2016

Effects of sphingosylphosphorylcholine on cryopreserved fat tissue graft survival

Yong Chan Bae, Chi Won Choi, Kyeong Wook Nam, Ji Sun Song, Jae Woo Lee

Pages: 3719-3724 Published online on: 26 August 2016

shRNA‑mediated silencing of TARBP2 inhibits NCI‑H1299 non‑small cell lung cancer cell invasion and migration via the JNK/STAT3/AKT pathway

Yue Shi, Duo Zuo, Xia Wang, Meng Han, Yan Wu

Pages: 3725-3730 Published online on: 06 September 2016

Clinical features and genetic diagnosis of hereditary spinocerebellar ataxia 3

Yaoguang Wang, Xiaokai Yang, Weide Ma, Jinxin Li, Qingyuan Zhang, Shuqi Xia, Hai Wang, Chenghui Zhang, Xiaomin Xu, Jiayong Zheng

Pages: 3731-3734 Published online on: 05 September 2016

Haptoglobin protein and mRNA expression in psoriasis and its clinical significance

Fu-Jun Tian, Ying-Ying Zhang, Li-Qian Liu, Ying Xiong, Zong-Shan Wang, Shou-Zhong Wang

Pages: 3735-3742 Published online on: 25 August 2016

Anti‑inflammatory effects of Ciwujianoside C3, extracted from the leaves of Acanthopanax henryi (Oliv.) Harms, on LPS‑stimulated RAW 264.7 cells

Da‑Hye Kang, Ok‑Hwa Kang, Zhi Li, Su‑Hyun Mun, Yun‑Soo Seo, Ryong Kong, Zhou Tian, Xiangqian Liu, Dong‑Yeul Kwon

Pages: 3749-3758 Published online on: 05 September 2016

Expression of far upstream element binding protein 1 in B‑cell non‑Hodgkin lymphoma is correlated with tumor growth and cell‑adhesion mediated drug resistance

Yuejiao Huang, Xiaohong Xu, Lili Ji, Yuchan Wang, Shitao Wang, Jie Tang, Xianting Huang, Xiaojing Yang, Yunhua He, Song He, Chun Cheng

Pages: 3759-3768 Published online on: 06 September 2016

Osteoprotective effects of osthole in a mouse model of 5/6 nephrectomy through inhibiting osteoclast formation

Xiaofeng Li, Chunchun Xue, Libo Wang, Dezhi Tang, Jian Huang, Yongjian Zhao, Yan Chen, Dongfeng Zhao, Qi Shi, Yongjun Wang, Bing Shu

Pages: 3769-3776 Published online on: 29 August 2016
Open Access

Antioxidant effects of Cirsium setidens extract on oxidative stress in human mesenchymal stem cells

Jun Hee Lee, Ho Kyung Jung, Yong‑Seok Han, Yeo Min Yoon, Chul Won Yun, Hwa Yeon Sun, Hyun Woo Cho, Sang Hun Lee

Pages: 3777-3784 Published online on: 05 September 2016

Bioinformatics analysis of gene expression profiles of dermatomyositis

Liang‑Yuan Chen, Zhao‑Lei Cui, Fan‑Cui Hua, Weng‑Jing Yang, Ye Bai, Feng‑Hua Lan

Pages: 3785-3790 Published online on: 02 September 2016

Low mutation percentage of KRAS and BRAF genes in Brazilian anal tumors

Lucas Tadeu Bidinotto, Carlos A R Véo, Edgar Aleman Loaiza, Alessandra Paulino Santos De França, Adriana Tarla Lorenzi, Luciana Albina Reis Rosa, Cristina Mendes De Oliveira, José Eduardo Levi, Cristovam Scapulatempo‑Neto, Adhemar Longatto‑Filho, Rui Manuel Reis

Pages: 3791-3797 Published online on: 26 August 2016

Glucocorticoid treatment inhibits intracerebral hemorrhage‑induced inflammation by targeting the microRNA‑155/SOCS‑1 signaling pathway

Hong‑Fei Xu, Xiao‑Yun Fang, Shao‑Hua Zhu, Xue‑Hua Xu, Zhi‑Xiang Zhang, Zu‑Feng Wang, Zi‑Qin Zhao, Yu‑Jie Ding, Lu‑Yang Tao

Pages: 3798-3804 Published online on: 06 September 2016

Possible tumor suppressive role of the miR-144/451 cluster in esophageal carcinoma as determined by principal component regression analysis

Zhikui Gao, Ran Liu, Juan Liao, Miao Yang, Enchun Pan, Lihong Yin, Yuepu Pu

Pages: 3805-3813 Published online on: 30 August 2016

Proteomic analysis of selective cytotoxic anticancer properties of flavonoids isolated from Citrus platymamma on A549 human lung cancer cells

Arulkumar Nagappan, Venu Venkatarame Gowda Saralamma, Gyeong Eun Hong, Ho Jeong Lee, Sung Chul Shin, Eun Hee Kim, Won Sup Lee, Gon Sup Kim

Pages: 3814-3822 Published online on: 24 August 2016

Identification of differentially expressed genes affecting hair and cashmere growth in the Laiwu black goat by microarray

Jinshan Zhao, Hegang Li, Kaidong Liu, Baoxun Zhang, Peipei Li, Jianning He, Ming Cheng, Wei De, Jifeng Liu, Yaofeng Zhao, Lihua Yang, Nan Liu

Pages: 3823-3831 Published online on: 06 September 2016

Effects of tongxinluo on angiogenesis in the carotid adventitia of hyperlipidemic rabbits

Jianhua Zhou, Bingfeng Cao, Weiping Ju, Sen Liu, Jianguang Song, Lixia Liu

Pages: 3832-3840 Published online on: 25 August 2016

Matrine induces the hepatic differentiation of WB-F344 rat hepatic progenitor cells and inhibits Jagged 1/HES1 signaling

Zhiyun Yang, Li Wang, Xianbo Wang

Pages: 3841-3847 Published online on: 24 August 2016

Nkx2.5/CARP signaling pathway contributes to the regulation of ion channel remodeling induced by rapid pacing in rat atrial myocytes

Wei Wang, Yun Zhu, Jianguang Yi, Wei Cheng

Pages: 3848-3854 Published online on: 06 September 2016

p53, Bcl-2 and cox-2 are involved in berberine hydrochloride-induced apoptosis of HeLa229 cells

Hai‑Yan Wang, Hai‑Zhong Yu, Sheng‑Mou Huang, Yu‑Lan Zheng

Pages: 3855-3861 Published online on: 31 August 2016

Comparison of bone marrow tissue- and adipose tissue-derived mesenchymal stem cells in the treatment of sepsis in a murine model of lipopolysaccharide-induced sepsis

Hao Ou, Shangping Zhao, Yue Peng, Xuefei Xiao, Qianlu Wang, Huaizeng Liu, Xianzhong Xiao, Mingshi Yang

Pages: 3862-3870 Published online on: 30 August 2016

S100B suppresses the differentiation of C3H/10T1/2 murine embryonic mesenchymal cells into osteoblasts

Dong Li, Kaihua Li, Gang Chen, Jianlong Xia, Ting Yang, Ping Cai, Chen Yao, Yongjiang Yang, Shichang Yan, Rihua Zhang, Hui Chen

Pages: 3878-3886 Published online on: 01 September 2016

Effect of high-fat diet-induced obesity on the Akt/FoxO/Smad signaling pathway and the follicular development of the mouse ovary

Yanqing Wu, Zhenghong Zhang, Xinghui Liao, Lingbin Qi, Yiping Liu, Zhengchao Wang

Pages: 3894-3900 Published online on: 25 August 2016

Mild hypothermia protects against early brain injury in rats following subarachnoid hemorrhage via the TrkB/ERK/CREB signaling pathway

Ou Lv, Fenggang Zhou, Yongri Zheng, Qingsong Li, Jianjiao Wang, Yulan Zhu

Pages: 3901-3907 Published online on: 05 September 2016

Regulation of the pacemaker activities in cultured interstitial cells of Cajal by Citrus unshiu peel extracts

Ji Hwan Shim, Soo Jin Lee, Huijin Gim, Hyun Jung Kim, Taewon Han, Jae Goo Kim, Eun Yeong Lim, Yun Tai Kim, Byung Joo Kim

Pages: 3908-3916 Published online on: 30 August 2016

Inhibiting the role of Skp2 suppresses cell proliferation and tumorigenesis of human gastric cancer cells via the upregulation of p27kip1

Yanguang Wen, Kuansong Wang, Kaiyan Yang

Pages: 3917-3924 Published online on: 25 August 2016

Activation of mTOR signaling leads to orthopedic surgery-induced cognitive decline in mice through β-amyloid accumulation and tau phosphorylation

Wenzhen Shen, Keliang Lu, Jiawan Wang, Anshi Wu, Yun Yue

Pages: 3925-3934 Published online on: 01 September 2016

Myeloid-derived suppressor cells are elevated in patients with psoriasis and produce various molecules

Dan Ilkovitch, Laura K. Ferris

Pages: 3935-3940 Published online on: 26 August 2016

Iodine regulates G2/M progression induced by CCL21/CCR7 interaction in primary cultures of papillary thyroid cancer cells with RET/PTC expression

You‑Yuan Zhang, Ze‑Bing Liu, Xuan‑Guang Ye, Wei‑Min Ren

Pages: 3941-3946 Published online on: 29 August 2016

Structure and antioxidant activity of a novel polysaccharide derived from Amanita caesarea

Yuanxiu Zhu, Xiang Ding, Mei Wang, Yiling Hou, Wanru Hou, Changwu Yue

Pages: 3947-3954 Published online on: 30 August 2016

SH003 selectively induces p73‑dependent apoptosis in triple‑negative breast cancer cells

Eun Kyoung Choi, Seung‑Mi Kim, Seung‑Woo Hong, Jai‑Hee Moon, Jae‑Sik Shin, Jeong Hee Kim, Ih‑Yeon Hwang, Soo‑A Jung, Dae‑Hee Lee, Eun Young Lee, Seul Lee, Hyunwoo Kim, Daejin Kim, Yeong Seok Kim, Youn Kyung Choi, Hyo In Kim, Hyeong Sim Choi, Sung‑Gook Cho, Jeong Eun Kim, Kyu Pyo Kim, Yong Sang Hong, Won Keun Lee, Jung Shin Lee, Tae Won Kim, Seong‑Gyu Ko, Dong‑Hoon Jin

Pages: 3955-3960 Published online on: 06 September 2016

Sp1 downregulates proinflammatory cytokine‑induced catabolic gene expression in nucleus pulposus cells

Kang Xu, Xiaofei Wang, Qianshi Zhang, Anjing Liang, Haipeng Zhu, Dongsheng Huang, Chunhai Li, Wei Ye

Pages: 3961-3968 Published online on: 06 September 2016

Influence of the availability of iron during hypoxia on the genes associated with apoptotic activity and local iron metabolism in rat H9C2 cardiomyocytes and L6G8C5 skeletal myocytes

Magdalena Dziegala, Monika Kasztura, Kamil Kobak, Jacek Bania, Waldemar Banasiak, Piotr Ponikowski, Ewa A. Jankowska

Pages: 3969-3977 Published online on: 05 September 2016

Role of histone modification in 12‑lipoxygenase‑associated p21 gene regulation

Yingchun Cui, Nian Liu, Fuzhe Ma, Weixia Sun, Hao Wu, Zhonggao Xu, Hang Yuan

Pages: 3978-3984 Published online on: 06 September 2016

Effects of endomorphin-1 postconditioning on myocardial ischemia/reperfusion injury and myocardial cell apoptosis in a rat model

Wei‑Ping Zhang, Qiao‑Feng Zong, Qin Gao, Ying Yu, Xiao‑Yu Gu, Ya Wang, Zheng‑Hong Li, Min Ge

Pages: 3992-3998 Published online on: 31 August 2016

Inhibiting autophagy promotes endoplasmic reticulum stress and the ROS‑induced nod‑like receptor 3‑dependent proinflammatory response in HepG2 cells

Jia‑Jing Yin, Guangying Xie, Ning Zhang, Yanbo Li

Pages: 3999-4007 Published online on: 05 September 2016
Open Access

[Retracted] Production of interleukin‑4 in CD133+ cervical cancer stem cells promotes resistance to apoptosis and initiates tumor growth

Chun‑Tao Liu, Ying Xin, Chun‑Yan Tong, Bing Li, Hong‑Li Bao, Cai‑Yun Zhang, Xue‑Hui Wang

Pages: 4008-4008 Published online on: 07 September 2016
Journal Cover

October 2016
Volume 14 Issue 4

Print ISSN: 1791-2997
Online ISSN: 1791-3004

2015 Impact Factor: 1.559
Ranked #48/123 Medicine Research and Experimental
(total number of cites)

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