Journal Articles

Open Access

Evaluation of urinary bladder fibrogenesis in a mouse model of long-term ketamine injection

Cheng‑Huang Shen, Shou‑Chieh Wang, Shou‑Tsung Wang, Shu‑Mei Lin, Jiann‑Der Wu, Chang‑Te Lin, Yi‑Wen Liu

Pages: 1880-1890 Published online on: 07 July 2016
Open Access

Disruption of kif3a results in defective osteoblastic differentiation in dental mesenchymal stem/precursor cells via the Wnt signaling pathway

Sicong Jiang, Guoqing Chen, Lian Feng, Zongting Jiang, Mei Yu, Jinku Bao, Weidong Tian

Pages: 1891-1900 Published online on: 12 July 2016
Open Access

Bufalin suppresses cancer stem-like cells in gemcitabine-resistant pancreatic cancer cells via Hedgehog signaling

Haiyong Wang, Zhouyu Ning, Yingyi Li, Xiaoyan Zhu, Zhiqiang Meng

Pages: 1907-1914 Published online on: 06 July 2016
Open Access

Caveolin-1 is critical in the proliferative effect of leptin on osteoblasts through the activation of Akt

Lin Zou, Guichun Zhang, Lifeng Liu, Chen Chen, Xuecheng Cao, Jinfang Cai

Pages: 1915-1922 Published online on: 01 July 2016
Open Access

The effect of LOXL2 in hepatocellular carcinoma

Linghong Wu, Yuan Zhang, Ying Zhu, Qingwei Cong, Yan Xiang, Linlin Fu

Pages: 1923-1932 Published online on: 06 July 2016
Open Access

Expression and clinical significance of Apollon in esophageal squamous cell carcinoma

Rong Li, Bo‑Lin Chen, Yan‑Wu Zhou, Ren‑Wei Guo, Meng‑Ting Shuai, Jun‑Xian Zeng, Ai‑Min Leng

Pages: 1933-1940 Published online on: 06 July 2016
Open Access

Molecular analysis of FGFR 2 and associated clinical observations in two Chinese families with Crouzon syndrome

Ying Lin, Hongbin Gao, Siming Ai, Jacob V.P. Eswarakumar, Tao Li, Bingqian Liu, Hongye Jiang, Yuhua Liu, Xialin Liu, Yonghao Li, Yao Ni, Jiangna Chen, Zhuoling Lin, Xiaoling Liang, Chenjin Jin, Xinhua Huang, Lin Lu, Yizhi Liu

Pages: 1941-1946 Published online on: 11 July 2016
Open Access

HIV‑1 downregulates the expression and phosphorylation of receptor tyrosine kinase by targeting the NF‑κB pathway

Tingting Feng, Jianhe Gan, Ailan Qin, Xiaoping Huang, Nanping Wu, Hua Hu, Hangping Yao

Pages: 1947-1952 Published online on: 08 July 2016
Open Access

mRNA expression of TLR4, TLR9 and NF-κB in a neonatal murine model of necrotizing enterocolitis

Yiyu Yin, Fengli Liu, Yiping Li, Ruze Tang, Jian Wang

Pages: 1953-1956 Published online on: 29 June 2016
Open Access

Aspirin inhibits osteoclastogenesis by suppressing the activation of NF-κB and MAPKs in RANKL-induced RAW264.7 cells

Yan‑Ping Zeng, Chao Yang, Yuan Li, Yong Fan, Hong‑Jun Yang, Bin Liu, Hong‑Xun Sang

Pages: 1957-1962 Published online on: 30 June 2016
Open Access

Antioxidant effect of angiotensin (1‑7) in the protection of pancreatic β cell function

Fen Zhang, Chang Liu, Lei Wang, Xi Cao, Ying Ying Wang, Jin Kui Yang

Pages: 1963-1969 Published online on: 13 July 2016
Open Access

A novel manganese complex selectively induces malignant glioma cell death by targeting mitochondria

Ji Geng, Jing Li, Tao Huang, Kaidi Zhao, Qiuyun Chen, Wenjie Guo, Jing Gao

Pages: 1970-1978 Published online on: 12 July 2016
Open Access

Endothelial lipase is upregulated by interleukin-6 partly via the p38 MAPK and p65 NF-κB signaling pathways

Xin Yue, Minghui Wu, Hong Jiang, Jing Hao, Qinghao Zhao, Qing Zhu, Gaowa Saren, Yun Zhang, Xiaoli Zhang

Pages: 1979-1985 Published online on: 30 June 2016
Open Access

Luteolin decreases the UVA‑induced autophagy of human skin fibroblasts by scavenging ROS

Miaomiao Yan, Zhongrong Liu, Huilan Yang, Cuihua Li, Hulin Chen, Yan Liu, Minling Zhao, Yingjie Zhu

Pages: 1986-1992 Published online on: 13 July 2016
Open Access

Directed differentiation of postnatal hippocampal neural stem cells generates nuclear receptor related‑1 protein‑ and tyrosine hydroxylase‑expressing cells

Yinxiu Ding, Zixin Zhang, Jiangbo Ma, Hechun Xia, Yin Wang, Yinming Liu, Quanrui Ma, Tao Sun, Juan Liu

Pages: 1993-1999 Published online on: 08 July 2016
Open Access

Investigation of the anti‑asthmatic activity of Oridonin on a mouse model of asthma

Jing Wang, Fengsen Li, Jianbing Ding, Ge Tian, Min Jiang, Zhen Gao, Ehbal Tuyghun

Pages: 2000-2006 Published online on: 08 July 2016
Open Access

Protection of rat liver against hepatic ischemia-reperfusion injury by a novel selenocysteine-containing 7-mer peptide

Qianqian Jiang, Yu Pan, Yupeng Cheng, Huiling Li, Hui Li

Pages: 2007-2015 Published online on: 01 July 2016
Open Access

Inhibitor of DNA binding 1 regulates cell cycle progression of endothelial progenitor cells through induction of Wnt2 expression

Xi Xia, Yang Yu, Li Zhang, Yang Ma, Hong Wang

Pages: 2016-2024 Published online on: 08 July 2016
Open Access

Effects of imatinib and nilotinib on the whole transcriptome of cultured murine osteoblasts

Gyöngyi Kirschner, Bernadett Balla, Péter Horváth, Andrea Kövesdi, Gergely Lakatos, István Takács, Zsolt Nagy, Bálint Tóbiás, Kristóf Árvai, János Pál Kósa, Péter Lakatos

Pages: 2025-2037 Published online on: 30 June 2016
Open Access

The expression pattern of Adam10 in the central nervous system of adult mice: Detection by in situ hybridization combined with immunohistochemistry staining

Zhi‑Bao Guo, Ying‑Ying Su, Yi‑Hui Wang, Wei Wang, Da‑Zhi Guo

Pages: 2038-2044 Published online on: 11 July 2016
Open Access

Dynamic co-expression network analysis of lncRNAs and mRNAs associated with venous congestion

Jinshun Li, Yuqin Xu, Jia Xu, Jinhua Wang, Liying Wu

Pages: 2045-2051 Published online on: 07 July 2016
Open Access

Role of platelet function and platelet membrane glycoproteins in children with primary immune thrombocytopenia

Wen-Jun Liu, Jing Bai, Qu-Lian Guo, Zhe Huang, Hong Yang, Yong-Qi Bai

Pages: 2052-2060 Published online on: 11 July 2016

A novel in-frame deletion in MEN1 (p.Ala416del) causes familial multiple endocrine neoplasia type 1 with an aggressive phenotype and unexpected inheritance pattern

Anna Skalniak, Grzegorz Sokołowski, Agata Jabrocka‑Hybel, Jakub Piątkowski, Magdalena Białas, Aleksandra Gilis‑Januszewska, Dorota Pach, Alicja Hubalewska‑Dydejczyk

Pages: 2061-2066 Published online on: 01 July 2016

Differential long non‑coding RNA and mRNA expression in differentiated human glioblastoma stem cells

Hao Li, Haowen Li, Yajing Hao, Yuming Jiao, Zhicen Li, Haiyan Yue, Zhe Xu, Shuo Wang, Yong Cao, Jizong Zhao

Pages: 2067-2076 Published online on: 12 July 2016

miRNA-30a functions as a tumor suppressor by downregulating cyclin E2 expression in castration-resistant prostate cancer

Lei Zhang, Xiao‑Wen Zhang, Chun‑Hui Liu, Kai Lu, Ye‑Qing Huang, Yi‑Duo Wang, Li Xing, Li‑Jie Zhang, Ning Liu, Hua Jiang, Chao Sun, Yu Yang, Shu‑Qiu Chen, Ming Chen, Bin Xu

Pages: 2077-2084 Published online on: 06 July 2016

Effects of microRNA‑338‑3p on morphine‑induced apoptosis and its underlying mechanisms

Hong‑Liang Weng, Ming‑Jing Wang

Pages: 2085-2092 Published online on: 12 July 2016

Dynamic metabolic profiling of urine biomarkers in rats with alcohol‑induced liver damage following treatment with Zhi‑Zi‑Da‑Huang decoction

Li An, Qiaoling Lang, Wenbin Shen, Qingshui Shi, Fang Feng

Pages: 2093-2100 Published online on: 11 July 2016

Enhanced expression levels of aquaporin-1 and aquaporin-4 in A549 cells exposed to silicon dioxide

Xiaohui Hao, Hongli Wang, Wei Liu, Shupeng Liu, Zihe Peng, Yue Sun, Jinyuan Zhao, Qiujie Jiang, Heliang Liu

Pages: 2101-2106 Published online on: 07 July 2016

Targeted next-generation sequencing identification of a novel missense mutation of the SKIV2L gene in a patient with trichohepatoenteric syndrome

Bixia Zheng, Jian Pan, Yu Jin, Chunli Wang, Zhifeng Liu

Pages: 2107-2110 Published online on: 11 July 2016

Silencing of osterix expression by siRNA inhibits aldosterone‑induced calcification of vascular smooth muscle cells in mice

Yan‑Chun Gong, Yue He, Hao Wang, Wen‑Quan Niu, Kai‑Da Ji, Hua Li

Pages: 2111-2118 Published online on: 08 July 2016

Sevoflurane inhibits the self-renewal of mouse embryonic stem cells via the GABAAR-ERK signaling pathway

Liuqing Yang, Yali Ge, Shunyan Lin, Xiangzhi Fang, Loujing Zhou, Ju Gao

Pages: 2119-2126 Published online on: 04 July 2016

microRNA-7 regulates cell growth, migration and invasion via direct targeting of PAK1 in thyroid cancer

Kai Yue, Xudong Wang, Yansheng Wu, Xuan Zhou, Qinghua He, Yuansheng Duan

Pages: 2127-2134 Published online on: 07 July 2016

B7-H4 expression in human infiltrating ductal carcinoma‑associated macrophages

Lei Liu, Dalin Li, Shuang Chen, Ran Zhao, Da Pang, Dianjun Li, Zhenkun Fu

Pages: 2135-2142 Published online on: 13 July 2016

Identification of a novel frameshift heterozygous deletion in exon 8 of the PAX6 gene in a pedigree with aniridia

Ozlem Giray Bozkaya, Esra Ataman, Ozge Aksel Kilicarslan, Tufan Cankaya, Ayfer Ulgenalp

Pages: 2150-2154 Published online on: 05 July 2016

The anti‑dengue virus properties of statins may be associated with alterations in the cellular antiviral profile expression

Owen Lloyd Bryan‑Marrugo, Daniel Arellanos-Soto, Augusto Rojas‑Martinez, Hugo Barrera‑Saldaña, Javier Ramos‑Jimenez, Roman Vidaltamayo, Ana María Rivas‑Estilla

Pages: 2155-2163 Published online on: 13 July 2016

Upregulation of kallikrein‑related peptidase 5 is associated with the malignant behavior of colorectal cancer

Yanhua Wu, Yingjian Chen, Qing Li, Yanwen Gong, Xiaohong Liu, Liquan Bi, Chengjin Hu

Pages: 2164-2170 Published online on: 13 July 2016

Suppression of tumor cell proliferation by quinine via the inhibition of the tumor necrosis factor receptor‑associated factor 6‑AKT interaction

Wenjuan Liu, Yonghao Qi, Lingyu Liu, Yu Tang, Jing Wei, Lijun Zhou

Pages: 2171-2179 Published online on: 11 July 2016

Identification of two novel mutations in the COMP gene in six families with pseudoachondroplasia

Wei‑Jia Yu, Zeng Zhang, Jin‑Wei He, Wen‑Zhen Fu, Chun Wang, Zhen‑Lin Zhang

Pages: 2180-2186 Published online on: 08 July 2016

Effects of irreversible electroporation on cervical cancer cell lines in vitro

Qin Qin, Zheng‑Ai Xiong, Ying Liu, Chen‑Guo Yao, Wei Zhou, Yuan‑Yuan Hua, Zhi‑Liang Wang

Pages: 2187-2193 Published online on: 05 July 2016

Anti‑migratory effect of rapamycin impairs allograft imaging by 18F‑fluorodeoxyglucose‑labeled splenocytes

Hukui Sun, Dayan Cheng, Yuanyuan Ma, Hong Liu, Ning Yang, Cong Zhang, Kai Wang, Guihua Hou, Huaiquan Wang

Pages: 2194-2198 Published online on: 12 July 2016

Quantitative PCR marker genes for endometrial adenocarcinoma

Alexandra C. Kölbl, Lisa‑Marie Victor, Amelie E. Birk, Udo Jeschke, Ulrich Andergassen

Pages: 2199-2205 Published online on: 07 July 2016

Alteration of the immune status of umbilical cord mesenchymal stem cells stimulated by TLR1/2 agonist, Pam3Csk

Pingxi Wang, Fanwei Zeng, Lina He, Jin Wang, Tingjiu Zhang, Dong Zhang

Pages: 2206-2212 Published online on: 13 July 2016

Confirming an integrated pathology of diabetes and its complications by molecular biomarker-target network analysis

Zide Zhao, Yingying Zhang, Fengchun Gai, Ying Wang

Pages: 2213-2221 Published online on: 07 July 2016

Inhibition of multiple myeloma cell proliferation by ginsenoside Rg3 via reduction in the secretion of IGF-1

Yan Li, Tao Yang, Jing Li, Hong‑Ling Hao, Su‑Yun Wang, Jie Yang, Jian‑Min Luo

Pages: 2222-2230 Published online on: 07 July 2016

Increased protein expression levels of pCREB, BDNF and SDF-1/CXCR4 in the hippocampus may be associated with enhanced neurogenesis induced by environmental enrichment

Xiao Qian Zhang, Jing Wei Mu, Hui Bin Wang, Jukka Jolkkonen, Ting Ting Liu, Ting Xiao, Mei Zhao, Chao Dong Zhang, Chuan Sheng Zhao

Pages: 2231-2237 Published online on: 06 July 2016

Aberrant expression of anaplastic lymphoma kinase in lung adenocarcinoma: Analysis of circulating free tumor RNA using one-step reverse transcription-polymerase chain reaction

Rossella Bruno, Mirella Giordano, Riccardo Giannini, Greta Alì, Gianfranco Puppo, Alessandro Ribechini, Antonio Chella, Gabriella Fontanini

Pages: 2238-2242 Published online on: 07 July 2016

Differential proteomics of the synovial membrane between bilateral and unilateral knee osteoarthritis in surgery‑induced rabbit models

Weilin Liu, Jian He, Ruhui Lin, Jie Liang, Qinglu Luo

Pages: 2243-2249 Published online on: 13 July 2016

Berberine enhances the anti‑tumor activity of tamoxifen in drug‑sensitive MCF‑7 and drug‑resistant MCF‑7/TAM cells

Chunjie Wen, Lanxiang Wu, Lijuan Fu, Xue Zhang, Honghao Zhou

Pages: 2250-2256 Published online on: 08 July 2016

Functional expression of human α7 nicotinic acetylcholine receptor in human embryonic kidney 293 cells

Yuan Gong, Ji‑Hong Jiang, Shi‑Tong Li

Pages: 2257-2263 Published online on: 11 July 2016

Increased levels of circulating adrenomedullin following treatment with TU‑100 in patients with Crohn's disease

Ken Kominato, Hiroshi Yamasaki, Keiichi Mitsuyama, Hidetoshi Takedatsu, Shinichiro Yoshioka, Kotaro Kuwaki, Teppei Kobayashi, Ryosuke Yamauchi, Shuhei Fukunaga, Osamu Tsuruta, Takuji Torimura

Pages: 2264-2268 Published online on: 08 July 2016

Platelet‑rich plasma promotes the migration and invasion of synovial fibroblasts in patients with rheumatoid arthritis

Shanshan Yan, Binzhou Yang, Chen Shang, Zhongshuang Ma, Zizheng Tang, Guiping Liu, Weigan Shen, Yu Zhang

Pages: 2269-2275 Published online on: 11 July 2016

Association between methylenetetrahydrofolate reductase (MTHFR) polymorphisms and susceptibility to Graves' ophthalmopathy

Jae Yeun Lee, Nam Keun Kim, Yong Wook Cho, Helen Lew

Pages: 2276-2282 Published online on: 30 June 2016

Dickkopf 2 promotes proliferation and invasion via Wnt signaling in prostate cancer

Wei Xu, Kuan Pang, Ze‑Guang Zhou, Yi‑Feng Chen, Ting Mo, Ming Li, Cheng‑Bei Liu

Pages: 2283-2288 Published online on: 11 July 2016

Pioglitazone affects the OPG/RANKL/RANK system and increase osteoclastogenesis

Fei Xu, Yonghui Dong, Xin Huang, Peng Chen, Fengjing Guo, Anmin Chen, Shilong Huang

Pages: 2289-2296 Published online on: 13 July 2016

microRNA-199a-3p functions as tumor suppressor by regulating glucose metabolism in testicular germ cell tumors

Xiaowen Liu, Hongyan Duan, Shihua Zhou, Zhiyong Liu, Daobing Wu, Ting Zhao, Shan Xu, Lifang Yang, Dan Li

Pages: 2311-2320 Published online on: 06 July 2016

Protective effect of cannabidiol on hydrogen peroxide‑induced apoptosis, inflammation and oxidative stress in nucleus pulposus cells

Jie Chen, Chen Hou, Xin Chen, Dong Wang, Pinglin Yang, Xijing He, Jinsong Zhou, Haopeng Li

Pages: 2321-2327 Published online on: 13 July 2016

miRNA polymorphisms (miR‑146a, miR‑149, miR‑196a2 and miR‑499) are associated with the risk of coronary artery disease

Jung‑Hoon Sung, Sang‑Hoon Kim, Woo‑In Yang, Won‑Jang Kim, Jae‑Youn Moon, In Jai Kim, Dong‑Hun Cha, Seung‑Yun Cho, Jung Oh Kim, Kyeong Ah Kim, Ok‑Joon Kim, Sang‑Wook Lim, Nam‑Keun Kim

Pages: 2328-2342 Published online on: 11 July 2016

Endostatin and irradiation modifies the activity of ADAM10 and neprilysin in breast cancer cells

Esra Arslan Aydemir, Ece Şimşek, Aylin Fidan Korcum, Kayahan Fişkin

Pages: 2343-2351 Published online on: 01 July 2016

Apigenin inhibits glioma cell growth through promoting microRNA-16 and suppression of BCL-2 and nuclear factor-κB/MMP‑9

Xin‑Jun Chen, Mian‑Yun Wu, Deng‑Hui Li, Jin You

Pages: 2352-2358 Published online on: 30 June 2016

Cytotoxic effects of NF‑κB inhibitors in combination with anti‑herpes agents on Epstein‑Barr virus‑positive gastric carcinoma in vitro

Paula Ordonez, Athira Nandakumar, Chihaya Koriyama, Megumi Yamomoto, Suminori Akiba

Pages: 2359-2367 Published online on: 11 July 2016
Open Access

Application of network construction to estimate functional changes to insulin receptor substrates 1 and 2 in Huh7 cells following infection with the hepatitis C virus

Jingkun Liu, Linbang Wang, Wenjun Wang, Yaping Li, Xiaoli Jia, Song Zhai, Juan Shi, Shuangsuo Dang

Pages: 2379-2388 Published online on: 18 July 2016
Open Access

The protective role of vitamin D3 in a murine model of asthma via the suppression of TGF-β/Smad signaling and activation of the Nrf2/HO-1 pathway

Zhihui Wang, Haitao Zhang, Xiaohan Sun, Lihong Ren

Pages: 2389-2396 Published online on: 27 July 2016
Open Access

Therapeutic effects of paeonol on methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid-induced Parkinson's disease in mice

Xiaojin Shi, Yu‑Hua Chen, Hao Liu, Hong‑Dang Qu

Pages: 2397-2404 Published online on: 28 July 2016

Proteomic analysis of the effects of CSF-1 and IL-1α on dental follicle cells

Chanchan Chen, Nan Xie, Junqi Ling, Yu Du, Haijing Gu

Pages: 2405-2414 Published online on: 28 July 2016
Open Access

Telocytes as potential targets in a cyclophosphamide-induced animal model of premature ovarian failure

Te Liu, Suwei Wang, Qiong Li, Yongyi Huang, Chuan Chen, Jin Zheng

Pages: 2415-2422 Published online on: 22 July 2016
Open Access

Trichostatin A increases the TIMP-1/MMP ratio to protect against osteoarthritis in an animal model of the disease

Hao Qu, Jin Li, Li‑Dong Wu, Wei‑Ping Chen

Pages: 2423-2430 Published online on: 18 July 2016
Open Access

Co-expression of ING4 and P53 enhances hypopharyngeal cancer chemosensitivity to cisplatin in vivo

Xin Ren, Hao Liu, Mingjie Zhang, Mengjun Wang, Shiyin Ma

Pages: 2431-2438 Published online on: 27 July 2016
Open Access

Molecular analysis of myocilin and optineurin genes in Korean primary glaucoma patients

Joonhong Park, Myungshin Kim, Chan Kee Park, Hyojin Chae, Seungok Lee, Yonggoo Kim, Woori Jang, Hyun Young Chi, Hae‑Young Lopilly Park, Shin Hae Park

Pages: 2439-2448 Published online on: 27 July 2016
Open Access

Semaphorin 3A-modified adipose-derived stem cell sheet may improve osseointegration in a type 2 diabetes mellitus rat model

Kaixiu Fang, Wen Song, Lifeng Wang, Xiaoru Xu, Naiwen Tan, Sijia Zhang, Hongbo Wei, Yingliang Song

Pages: 2449-2456 Published online on: 28 July 2016
Open Access

LncRNA HOTAIR controls the expression of Rab22a by sponging miR-373 in ovarian cancer

Zhongbao Zhang, Jiajing Cheng, Yi Wu, Jin Qiu, Yi Sun, Xiaowen Tong

Pages: 2465-2472 Published online on: 28 July 2016
Open Access

Wnt3a is critical for endothelial progenitor cell-mediated neural stem cell proliferation and differentiation

Yibin Du, Shuo Zhang, Tao Yu, Gongwen Du, Hui Zhang, Zongsheng Yin

Pages: 2473-2482 Published online on: 01 August 2016
Open Access

Resistant mechanisms and molecular epidemiology of imipenem-resistant Acinetobacter baumannii

Shu‑Zhen Xiao, Hai‑Qing Chu, Li‑Zhong Han, Zhe‑Min Zhang, Bing Li, Lan Zhao, Liyun Xu

Pages: 2483-2488 Published online on: 22 July 2016
Open Access

Downregulation of thrombospondin-1 by DNA hypermethylation is associated with tumor progression in laryngeal squamous cell carcinoma

Chuang Huang, Xiaohong Zhou, Zhenhua Li, Hong Liu, Yun He, Guo Ye, Kun Huang

Pages: 2489-2496 Published online on: 01 August 2016
Open Access

Cerebral vasoconstriction reactions and plasma levels of ETBR, ET-1, and eNOS in patients with chronic high altitude disease

Shizheng Wu, Guisheng Hao, Shukun Zhang, Dongmei Jiang, Tana Wuren, Junming Luo

Pages: 2497-2502 Published online on: 27 July 2016
Open Access

MicroRNA-363 and GATA-1 are regulated by HIF-1α in K562 cells under hypoxia

Youbang Xie, Wenqian Li, Jianming Feng, Tianyi Wu, Jianping Li

Pages: 2503-2510 Published online on: 29 July 2016
Open Access

Effects of cisplatin on the LSD1-mediated invasion and metastasis of prostate cancer cells

Zhi‑Yuan Chen, Hui Chen, Tao Qiu, Xiao‑Dong Weng, Jia Guo, Lei Wang, Xiu‑Heng Liu

Pages: 2511-2517 Published online on: 28 July 2016
Open Access

Low-dose testosterone alleviates vascular damage caused by castration in male rats in puberty via modulation of the PI3K/AKT signaling pathway

Jing Zhao, Ge‑Li Liu, Ying Wei, Li‑Hong Jiang, Peng‑Li Bao, Qing‑Yan Yang

Pages: 2518-2526 Published online on: 27 July 2016
Open Access

Generation of porcine fetal fibroblasts expressing the tetracycline-inducible Cas9 gene by somatic cell nuclear transfer

Guoqian Liu, Kai Liu, Hengxi Wei, Li Li, Shouquan Zhang

Pages: 2527-2533 Published online on: 19 July 2016
Open Access

α-TEA inhibits the growth and motility of human colon cancer cells via targeting RhoA/ROCK signaling

Jialin Yao, Peng Gao, Yang Xu, Zhaozhu Li

Pages: 2534-2540 Published online on: 18 July 2016
Open Access

Loss of coxsackie and adenovirus receptor expression in human colorectal cancer: A potential impact on the efficacy of adenovirus-mediated gene therapy in Chinese Han population

Ying‑Yu Ma, Xiao‑Jun Wang, Yong Han, Gang Li, Hui‑Ju Wang, Shi‑Bing Wang, Xiao‑Yi Chen, Fan‑Long Liu, Xiang‑Lei He, Xiang‑Min Tong, Xiao‑Zhou Mou

Pages: 2541-2547 Published online on: 21 July 2016
Open Access

Co-expression of autophagic markers following photodynamic therapy in SW620 human colon adenocarcinoma cells

Barbara Ziółkowska, Marta Woźniak, Piotr Ziółkowski

Pages: 2548-2554 Published online on: 25 July 2016
Open Access

Analysis of different components in the peritumoral tissue microenvironment of colorectal cancer: A potential prospect in tumorigenesis

Chao Huang, Hong Liu, Xiuli Gong, Bin Wen, Dan Chen, Jinyuan Liu, Fengliang Hu

Pages: 2555-2565 Published online on: 01 August 2016
Open Access

Dysregulated function of normal human epidermal keratinocytes in the absence of filaggrin

Ningning Dang, Xiaoli Ma, Xianguang Meng, Liguo An, Shuguang Pang

Pages: 2566-2572 Published online on: 22 July 2016
Open Access

Rescued expression of WIF-1 in gallbladder cancer inhibits tumor growth and induces tumor cell apoptosis with altered expression of proteins

Yan Huang, Qiang Du, Weibao Wu, Feifei She, Yanling Chen

Pages: 2573-2581 Published online on: 19 July 2016
Open Access

Neuroprotection induced by post-conditioning following ischemia/reperfusion in mice is associated with altered microRNA expression

Wei Miao, Tian‑Hao Bao, Jian‑Hong Han, Mei Yin, Jie Zhang, Yong Yan, Yu‑Hong Zhu

Pages: 2582-2588 Published online on: 29 July 2016
Open Access

Zisheng Shenqi decoction ameliorates monosodium urate crystal-induced gouty arthritis in rats through anti-inflammatory and anti-oxidative effects

Jieru Han, Ying Xie, Fangyu Sui, Chunhong Liu, Xiaowei Du, Chenggang Liu, Xiaoling Feng, Deyou Jiang

Pages: 2589-2597 Published online on: 18 July 2016
Open Access

Tumorigenic lung tumorospheres exhibit stem-like features with significantly increased expression of CD133 and ABCG2

Wensi Zhao, Yi Luo, Boyi Li, Tao Zhang

Pages: 2598-2606 Published online on: 18 July 2016
Open Access

Angiopoietin-like protein 2 expression is suppressed by angiotensin II via the angiotensin II type 1 receptor in rat cardiomyocytes

Shuya Wang, Ying Li, Wei Miao, Hong Zhao, Feng Zhang, Nan Liu, Guohai Su, Xiaojun Cai

Pages: 2607-2613 Published online on: 25 July 2016
Open Access

Neuregulin-1 (Nrg1) signaling has a preventive role and is altered in the frontal cortex under the pathological conditions of Alzheimer's disease

Qiong Jiang, Shuangxi Chen, Chengliang Hu, Peizhi Huang, Huifan Shen, Weijiang Zhao

Pages: 2614-2624 Published online on: 25 July 2016
Open Access

The clinical significance of forkhead box protein A1 and its role in colorectal cancer

Wenqi Ma, Jue Jiang, Miao Li, Hua Wang, Hongli Zhang, Xin He, Lili Huang, Qi Zhou

Pages: 2625-2631 Published online on: 01 August 2016

Peripheral KATP activation inhibits pain sensitization induced by skin/muscle incision and retraction via the nuclear factor-κB/c-Jun N-terminal kinase signaling pathway

Li‑Ping Qian, Shi‑Ren Shen, Jun‑Jie Chen, Lu‑Lu Ji, Su Cao

Pages: 2632-2638 Published online on: 27 July 2016

Identification of a PTPN11 hot spot mutation in a child with atypical LEOPARD syndrome

Jia Zhang, Jinwen Shen, Ruhong Cheng, Cheng Ni, Jianying Liang, Ming Li, Zhirong Yao

Pages: 2639-2643 Published online on: 27 July 2016

Vitamin D induces autophagy of pancreatic β-cells and enhances insulin secretion

Yubin Wang, Dawei He, Chengpei Ni, Huiying Zhou, Shuyan Wu, Zhimou Xue, Zhengyu Zhou

Pages: 2644-2650 Published online on: 19 July 2016

MicroRNA-101 inhibits the proliferation and invasion of bladder cancer cells via targeting c-FOS

Yongqi Long, Zhiping Wu, Xinhua Yang, Lei Chen, Zhijun Han, Yulong Zhang, Jinge Liu, Wenjin Liu, Xinyi Liu

Pages: 2651-2656 Published online on: 20 July 2016

MicroRNA-610 is downregulated in glioma cells, and inhibits proliferation and motility by directly targeting MDM2

Yu Yan, Yong Peng, Yangzhu Ou, Yugang Jiang

Pages: 2657-2664 Published online on: 27 July 2016
Open Access

Wtip is required for proepicardial organ specification and cardiac left/right asymmetry in zebrafish

Rebecca Powell, Ekaterina Bubenshchikova, Yayoi Fukuyo, Chaonan Hsu, Olga Lakiza, Hiroki Nomura, Erin Renfrew, Deborah Garrity, Tomoko Obara

Pages: 2665-2678 Published online on: 27 July 2016

Combined therapeutic effects of bortezomib and anacardic acid on multiple myeloma cells via activation of the endoplasmic reticulum stress response

Xiaoxian Dong, Yuning Liao, Ningning Liu, Xianliang Hua, Jianyu Cai, Jinbao Liu, Hongbiao Huang

Pages: 2679-2684 Published online on: 19 July 2016

Resveratrol inhibits phosphorylation within the signal transduction and activator of transcription 3 signaling pathway by activating sirtuin 1 in SW1353 chondrosarcoma cells

Haidong Jin, Hui Chen, Kehe Yu, Jingdong Zhang, Bin Li, Ningyu Cai, Jun Pan

Pages: 2685-2690 Published online on: 27 July 2016

In vitro and in vivo anti-Vibrio vulnificus activity of psammaplin A, a natural marine compound

Byung Cheol Lee, Arim Lee, Jee Hyung Jung, Sang Ho Choi, Tae Sung Kim

Pages: 2691-2696 Published online on: 18 July 2016

Astaxanthin blocks preeclampsia progression by suppressing oxidative stress and inflammation

Rong‑Rong Xuan, Ting‑Ting Niu, Hai‑Min Chen

Pages: 2697-2704 Published online on: 28 July 2016

CIP2A regulates proliferation and apoptosis of multiple myeloma cells

Zhuanzhen Zheng, Zhenhua Qiao, Wenliang Chen, Rong Gong, Yalin Wang, Lianrong Xu, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong

Pages: 2705-2709 Published online on: 27 July 2016

Mild Camurati‑Engelamann disease presenting with exophthalmos as the first and only manifestation: A case report

Ruizhi Jiajue, Bo Wu, Yan Jiang, Ou Wang, Mei Li, Xiaoping Xing, Weibo Xia

Pages: 2710-2716 Published online on: 27 July 2016

Umbilical cord-derived mesenchymal stem cells inhibit growth and promote apoptosis of HepG2 cells

Ying‑Mei Tang, Wei‑Min Bao, Jin‑Hui Yang, Lin‑Kun Ma, Jing Yang, Ying Xu, Li‑Hong Yang, Feng Sha, Zhi‑Yuan Xu, Hua‑Mei Wu, Wei Zhou, Yan Li, Yu‑Hua Li

Pages: 2717-2724 Published online on: 21 July 2016

Functional study of the upregulation of miRNA-27a and miRNA-27b in 3T3-L1 cells in response to berberine

Yue‑Yue Wu, Xin‑Mei Huang, Jun Liu, Ying Cha, Zao‑Ping Chen, Fang Wang, Jiong Xu, Li Sheng, He‑Yuang Ding

Pages: 2725-2731 Published online on: 25 July 2016

Elevated DRD4 promoter methylation increases the risk of Alzheimer's disease in males

Huihui Ji, Yunliang Wang, Danjie Jiang, Guili Liu, Xuting Xu, Dongjun Dai, Xiaohui Zhou, Wei Cui, Jinfeng Li, Zhongming Chen, Ying Li, Dongsheng Zhou, Qin Zha, Renjie Zhuo, Liting Jiang, Yu Liu, Lili Shen, Beibei Zhang, Lei Xu, Haochang Hu, Yuzheng Zhang, Honglei Yin, Shiwei Duan, Qinwen Wang

Pages: 2732-2738 Published online on: 27 July 2016

Hypermethylation of CDH13, DKK3 and FOXL2 promoters and the expression of EZH2 in ovary granulosa cell tumors

Yanmei Xu, Xia Li, Hongtao Wang, Pengmu Xie, Xun Yan, Yu Bai, Tingguo Zhang

Pages: 2739-2745 Published online on: 18 July 2016

Immunomodulatory effects of Longdan Xiegan Tang on CD4+/CD8+ T cells and associated inflammatory cytokines in rats with experimental autoimmune uveitis

Kai Tang, Dadong Guo, Lian Zhang, Junguo Guo, Fengming Zheng, Junkang Si, Hongsheng Bi

Pages: 2746-2754 Published online on: 27 July 2016

Modulatory effects of levamisole and garlic oil on the immune response of Wistar rats: Biochemical, immunohistochemical, molecular and immunological study

Essam Hassan Mohamed, Ahmed Abdel‑Aziz Baiomy, Zein Shaban Ibrahim, Mohamed Mohamed Soliman

Pages: 2755-2763 Published online on: 27 July 2016

The pro-oxidant gene p66shc increases nicotine exposure-induced lipotoxic oxidative stress in renal proximal tubule cells

Istvan Arany, Samuel Hall, Dustin K. Reed, Mehul Dixit

Pages: 2771-2777 Published online on: 25 July 2016

Neuroprotective effect of ginsenoside Rg1 prevents cognitive impairment induced by isoflurane anesthesia in aged rats via antioxidant, anti-inflammatory and anti-apoptotic effects mediated by the PI3K/AKT/GSK-3β pathway

Yini Zhang, Zhao Zhang, Haitang Wang, Nan Cai, Shuang Zhou, Yaoping Zhao, Xue Chen, Shaoqiang Zheng, Qi Si, Wei Zhang

Pages: 2778-2784 Published online on: 27 July 2016

Synergy between von Hippel-Lindau and P53 contributes to chemosensitivity of clear cell renal cell carcinoma

Ziyi Zhao, Changjin Chen, Junzhi Lin, Wentong Zeng, Juan Zhao, Yindan Liang, Qinrui Tan, Chao Yang, Hui Li

Pages: 2785-2790 Published online on: 27 July 2016

Atorvastatin ameliorates endothelium-specific insulin resistance induced by high glucose combined with high insulin

Ou Yang, Jinliang Li, Haiyan Chen, Jie Li, Jian Kong

Pages: 2791-2798 Published online on: 27 July 2016

Celastrol inhibits IL-1β-induced inflammation in orbital fibroblasts through the suppression of NF-κB activity

Hong Li, Yifei Yuan, Yali Zhang, Qianwen He, Rongjuan Xu, Fangfang Ge, Chen Wu

Pages: 2799-2806 Published online on: 28 July 2016

Prenatal valproate treatment produces autistic-like behavior and increases metabotropic glutamate receptor 1A-immunoreactivity in the hippocampus of juvenile rats

Francisco Peralta, Constanza Fuentealba, Jenny Fiedler, Esteban Aliaga

Pages: 2807-2814 Published online on: 18 July 2016

Expression of interferon regulatory factor 5 is regulated by the Sp1 transcription factor

Jin Shu, Xiao‑Hua Wang, Lan‑Bo Zhou, Chun‑Ming Jiang, Wei‑Xia Yang, Rui Jin, Lu‑Lu Wang, Guo‑Ping Zhou

Pages: 2815-2822 Published online on: 27 July 2016

Identifying the role of Wilms tumor 1 associated protein in cancer prediction using integrative genomic analyses

Li‑Sheng Wu, Jia‑Yi Qian, Minghai Wang, Haiwei Yang

Pages: 2823-2831 Published online on: 18 July 2016

Effect of evodiamine on the proliferation and apoptosis of A549 human lung cancer cells

Li Lin, Li Ren, Liujing Wen, Yu Wang, Jin Qi

Pages: 2832-2838 Published online on: 29 July 2016

Downregulation of AATK mediates microRNA-558-induced resistance of A549 cells to radiotherapy

Rui‑Xia Zhu, Chun‑Hui Song, Jin‑Shan Yang, Qing‑Ting Yi, Bao‑Jian Li, Si‑Hai Liu

Pages: 2846-2852 Published online on: 01 August 2016

Nitidine chloride inhibits proliferation, induces apoptosis via the Akt pathway and exhibits a synergistic effect with doxorubicin in ovarian cancer cells

Feng Ding, Tianfeng Liu, Nina Yu, Shihong Li, Xiaofei Zhang, Guanghong Zheng, Chunming Lv, Kai Mou, Jia Xu, Bo Li, Surong Wang, Haibo Song

Pages: 2853-2859 Published online on: 29 July 2016

MicroRNA-26a protects against cardiac hypertrophy via inhibiting GATA4 in rat model and cultured cardiomyocytes

Yan Liu, Zhiqian Wang, Wenliang Xiao

Pages: 2860-2866 Published online on: 28 July 2016

miR-22-5p revealed as a potential biomarker involved in the acute phase of myocardial infarction via profiling of circulating microRNAs

Agata Maciejak, Marek Kiliszek, Grzegorz Opolski, Agnieszka Segiet, Krzysztof Matlak, Slawomir Dobrzycki, Dorota Tulacz, Grazyna Sygitowicz, Beata Burzynska, Monika Gora

Pages: 2867-2875 Published online on: 27 July 2016
Journal Cover

September 2016
Volume 14 Issue 3

Print ISSN: 1791-2997
Online ISSN: 1791-3004

2015 Impact Factor: 1.559
Ranked #48/123 Medicine Research and Experimental
(total number of cites)

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