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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2026 Volume 34 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Chronic kidney disease‑associated encephalopathy: Clinical features, pathomechanisms and emerging therapeutic strategies (Review)

Nanling Zeng, Ling Jiang, Yang Zhang, Jian Liu, Qiong Zhang, Lishang Liao, Qiongdan Hu
Article Number: 259
Published online on: 21 July 2026

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Retraction Open Access

[Retracted] Emodin promotes the arrest of human lymphoma Raji cell proliferation through the UHRF1‑DNMT3A‑∆Np73 pathways

Yun Lin, Weiming Chen, Zhihong Wang, Pengwei Cai
Article Number: 258
Published online on: 20 July 2026

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Article Open Access

Sedanolide alleviates LPS‑induced depressive‑like behaviors by modulating the C3a/C3aR signaling axis and microglial glycolysis

Shaocong Lu, Fangla Luo, Niqi Chen, Gongde Shi, Yeru Chen
Article Number: 257
Published online on: 16 July 2026

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Expression of Concern Open Access

[Expression of Concern] Chrysophanol inhibits proliferation and induces apoptosis through NF‑κB/cyclin D1 and NF‑κB/Bcl‑2 signaling cascade in breast cancer cell lines

Li Ren, Zhouping Li, Chunmei Dai, Danyu Zhao, Yanjie Wang, Chunyu Ma, Chun Liu
Article Number: 256
Published online on: 15 July 2026

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Article Open Access

PCSK9 alleviates doxorubicin‑induced pyroptosis of cardiomyocytes

Chaochu Cui, Jinyu Zhao, Xiaoqian Li, Shengming Huang, Gang Liu, Xinhui Xu, Can Guo, Tiesuo Zhao, Jiang Du, Shipeng Li, Xianwei Wang, Jianbo Yang
Article Number: 255
Published online on: 14 July 2026

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Review Open Access

From cell to disease: Regulatory networks and mechanisms of super‑enhancers in aging (Review)

Xiaodan Wang, Weiqian Deng, Shuangxi Tu, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 254
Published online on: 14 July 2026

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Retraction Open Access

[Retracted] Matrine‑induced apoptosis in Hep3B cells via the inhibition of MDM2

Ning Zhou, Jiequn Li, Ting Li, Guangshun Chen, Zhongqiang Zhang, Zhongzhou Si
Article Number: 253
Published online on: 13 July 2026

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Review Open Access

Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review)

Lan Wang, Zhiyuan Ma, Bei Ji, Shuhui Liu, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 252
Published online on: 09 July 2026

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Article

Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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Correction Open Access

[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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Review Open Access

A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
Published online on: 07 July 2026

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Review Open Access

Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Article Open Access

Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Review Open Access

Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Review Open Access

Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Article Open Access

Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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Review Open Access

TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Article Open Access

Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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Retraction Open Access

[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Article Open Access

Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Article Open Access

Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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Journal Cover
October-2026 Volume 34 Issue 4

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Expression of Concern Open Access

[Expression of Concern] MicroRNA‑145‑5p suppresses fascin to inhibit the invasion and migration of cervical carcinoma cells

Shufang He, Guiyuan Yu, Ke Peng, Sisun Liu
Article Number: 277
Published online on: 12 August 2026

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Review

Research progress on drugs targeting mitochondria‑associated membranes for the treatment of atherosclerosis (Review)

Shaoying An, Wenhui Sun, Lizhou Shi, Hai Chen, Zhongcheng Mo
Article Number: 276
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] A study of Sirt1 regulation and the effect of resveratrol on synoviocyte invasion and associated joint destruction in rheumatoid arthritis

Liang Hao, Yuying Wan, Uhua Xiao, Qiang Tang, Huan Deng, Lu Chen
Article Number: 275
Published online on: 10 August 2026

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Article Open Access

Histone deacetylase 3‑mediated histone deacetylation combined with activating transcription factor 3 promotes renal fibrosis by inhibiting Klotho

Zhiying Yang, Xueling Wang, Wenhong Li, Hao Chen, Gang Liu
Article Number: 274
Published online on: 06 August 2026

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Review Open Access

Mitochondrial quality control in acute liver injury and its therapeutic implications (Review)

Ziqiang Chen, Yunhe Wang, Yijing Li, Gang Cong, Yunhang Chu, Yunhui Bai, Yishuo Zhang, Liya Zhou
Article Number: 273
Published online on: 05 August 2026

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Article Open Access

STC1 promotes osteogenic differentiation and represses inflammation via inhibition of NF‑κB signaling in mesenchymal stromal cells

Chen Yang, Xin Li, Peng Wang, Yitong Chen, Erli Wu, Qian Chen, Jing Hu, Fu Zheng, Lamu Gongsang, Jiayu Li, Mengyuan Zhang, Jing Zhou, Bing Han, Amr A. Badreldin, Yuka Miyamoto, Jin Koo Kim, Insoon Chang, Jia Chang, Paul H. Krebsbach, Liyuan Huang, Xiaoping Xu, Xiaoyan Chen, Peng Deng, Qianming Chen, Lijie Fan
Article Number: 272
Published online on: 05 August 2026

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Review Open Access

Research progress on the protective effect and oxidative stress mechanism of rutin against liver injury (Review)

Teng Sun, Lei Ye
Article Number: 271
Published online on: 04 August 2026

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Review Open Access

Role of microbial metabolites in the pathogenesis of hypertensive disorders of pregnancy: From short‑chain fatty acids to tryptophan metabolites (Review)

Fengyun Gao, Lili Wang, Guiyun Teng, Liqiong Shang
Article Number: 270
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Tumor promoter role of miR‑647 in gastric cancer via repression of TP73

Xiangqian Zhang, Min Zhang, Guifeng Wang, Ye Tian, Xiaolong He
Article Number: 269
Published online on: 03 August 2026

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Review Open Access

Gut microbiota‑immune crosstalk in recurrent pregnancy loss: Mechanisms and therapeutic perspectives (Review)

Nanjian Luo, Han Hu, Xiaoting Zeng, Yi Huan Zhang, Qi Deng, En Ni Tang, Yu Hu
Article Number: 268
Published online on: 31 July 2026

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Review Open Access

Integrating gut‑brain axis insights into bundled nutrition care for critically ill patients: From mechanisms to implementation (Review)

Liqi Zhang, Shuxia Yang, Huiyan Wu, Hong Zhou
Article Number: 267
Published online on: 30 July 2026

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Review Open Access

Role of CMTM6 in disease pathogenesis and clinical translation potential (Review)

Rongtou Huang, Danning Mo, Huitian Huang, Minmin Zhang, Wenhong Yu, Buqing Cao
Article Number: 266
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Identification of key differentially expressed genes associated with non‑small cell lung cancer by bioinformatics analyses

Yubo Xiao, Min Feng, Haiying Ran, Xiao Han, Xuegang Li
Article Number: 265
Published online on: 29 July 2026

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Review Open Access

Advances in miR‑200c regulation of apoptosis, pyroptosis and autophagy in disease (Review)

Xiaona Wang, Hua Du, Yingxu Shi
Article Number: 264
Published online on: 28 July 2026

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Review Open Access

Association between periodontitis and heart failure: Mechanisms and clinical implications (Review)

Xinyue Zhang, Xiaoli An
Article Number: 263
Published online on: 28 July 2026

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Article Open Access

Ginsenosides alleviate the progression of hepatic fibrosis by targeting the liver circadian clock gene CLOCK

Jiawen Yu, Chunmei Qian, Renye Que, Yi Zhou
Article Number: 262
Published online on: 28 July 2026

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Retraction Open Access

[Retracted] PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin, Yuezhong Shen, Jingyang Su
Article Number: 261
Published online on: 27 July 2026

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Article Open Access

UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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Article

Ivermectin as an inhibitor of cancer stem‑like cells

Guadalupe Dominguez‑Gomez, Alma Chavez‑Blanco, Jose Luis Medina‑Franco, Fernanda Saldivar‑Gonzalez, Ytzel Flores‑Torrontegui, Mandy Juarez, José Díaz‑Chávez, Aurora Gonzalez‑Fierro, Alfonso Dueñas‑González

Pages: 3397-3403
Published online on: 08 December 2017
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Review

Chamomile: A herbal medicine of the past with a bright future (Review)

Janmejai K. Srivastava, Eswar Shankar, Sanjay Gupta

Pages: 895-901
Published online on: 27 September 2010
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Article

Low‑molecular weight fucoidan inhibits the differentiation of osteoclasts and reduces osteoporosis in ovariectomized rats

Xin Jin, Liguo Zhu, Xiulan Li, Jian Jia, Yang Zhang, Xiaolei Sun, Jianxiong Ma, Zhaojie Liu, Xinlong Ma

Pages: 890-898
Published online on: 20 December 2016
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Article Open Access

Antiadipogenic effects of subthermal electric stimulation at 448 kHz on differentiating human mesenchymal stem cells

María Luisa Hernández‑Bule, Javier Martínez‑Botas, María Ángeles Trillo, Carlos L Paíno, Alejandro Úbeda

Pages: 3895-3903
Published online on: 21 March 2016
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Review Open Access

Molecular insights into the benefits of nicotine on memory and cognition (Review)

Ahmad Alhowail

Article Number: 398
Published online on: 25 March 2021
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Article Open Access

Polydeoxyribonucleotide exerts opposing effects on ERK activity in human skin keratinocytes and fibroblasts

Sun Mee Shin, Eun Joo Baek, Kwang Ho Kim, Kwang Joong Kim, Eun Joo Park

Article Number: 148
Published online on: 20 June 2023
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Article Open Access

Hair growth is promoted by BeauTop via expression of EGF and FGF‑7

Chien‑Ying Lee, Chi‑Yu Yang, Ching‑Che Lin, Min‑Chien Yu, Shuenn‑Jyi Sheu, Yu‑Hsiang Kuan

Pages: 8047-8052
Published online on: 23 April 2018
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Article

Composition and antioxidant activity of water-soluble oligosaccharides from Hericium erinaceus

Yiling Hou, Xiang Ding, Wanru Hou

Pages: 3794-3799
Published online on: 19 December 2014
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Article

Effects of exercise therapy on knee joint function and synovial fluid cytokine levels in patients with knee osteoarthritis

Shao-Lan Zhang, Hong-Qi Liu, Xiao-Zu Xu, Juan Zhi, Jiao-Jiao Geng, Jin Chen

Pages: 183-186
Published online on: 07 November 2012
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Review Open Access

Perspectives of small molecule inhibitors of activin receptor‑like kinase in anti‑tumor treatment and stem cell differentiation (Review)

Xueling Cui, Shumi Shang, Xinran Lv, Jing Zhao, Yan Qi, Zhonghui Liu

Pages: 5053-5062
Published online on: 30 April 2019
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Article

D-limonene exhibits anti-inflammatory and antioxidant properties in an ulcerative colitis rat model via regulation of iNOS, COX-2, PGE2 and ERK signaling pathways

Lihua Yu, Jing Yan, Zhiguang Sun

Pages: 2339-2346
Published online on: 22 February 2017
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Review Open Access

Acute spinal cord injury: Pathophysiology and pharmacological intervention (Review)

Yi Zhang, Abdullah Al Mamun, Yuan Yuan, Qi Lu, Jun Xiong, Shulin Yang, Chengbiao Wu, Yanqing Wu, Jian Wang

Article Number: 417
Published online on: 31 March 2021
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Article Open Access

Small molecular compounds efficiently convert human fibroblasts directly into neurons

Jijuan Yang, Huimei Cao, Shengnan Guo, Hong Zhu, Hong Tao, Linna Zhang, Zhangping Chen, Tao Sun, Shuhong Chi, Qikuan Hu

Pages: 4763-4771
Published online on: 02 October 2020
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Article

Development of neutralization antibodies against highly pathogenic H5N1 avian influenza virus using ostrich (Struthio camelus) yolk

Kazuhide Adachi, Ekowati Handharyani, Dwi Kesuma Sari, Kentaro Takama, Keiko Fukuda, Isako Endo, Ryohei Yamamoto, Masaki Sawa, Masaru Tanaka, Itsuro Konishi, Yasuhiro Tsukamoto

Pages: 203-209
Published online on: 01 March 2008
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Upregulation of ADAMTS‑7 and downregulation of COMP are associated with aortic aneurysm

Wei Qin, Yide Cao, Liangpeng Li, Wen Chen, Xin Chen

Pages: 5459-5463
Published online on: 21 August 2017
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Article

Taraxacum mongolicum extract exhibits a protective effect on hepatocytes and an antiviral effect against hepatitis B virus in animal and human cells

Yuan-Yuan Jia, Rong-Fa Guan, Yi-Hang Wu, Xiao-Ping Yu, Wen-Yan Lin, Yong-Yong Zhang, Tao Liu, Jun Zhao, Shu-Yun Shi, Yu Zhao

Pages: 1381-1387
Published online on: 29 January 2014
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Article Open Access

Placental expression of PAPPA, PAPPA-2 and PLAC-1 in pregnacies is associated with FGR

Stavros Sifakis, Vasilis P. Androutsopoulos, Artemis Pontikaki, Alexis Velegrakis, George I. Papaioannou, Ourania Koukoura, Demetrios A. Spandidos, Nikos Papantoniou

Pages: 6435-6440
Published online on: 09 March 2018
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Article Open Access

COL1A1 promotes metastasis in colorectal cancer by regulating the WNT/PCP pathway

Zheying Zhang, Yongxia Wang, Jinghang Zhang, Jiateng Zhong, Rui Yang

Pages: 5037-5042
Published online on: 01 February 2018
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Article Open Access

Mesenchymal stem cell‑derived exosomes loaded with 5‑Fu against cholangiocarcinoma <em>in vitro</em>

Mingzheng Chen, Yangyang Li, Ningfu Ma, Jinfeng Zang

Article Number: 213
Published online on: 09 May 2022
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Article Open Access

Chimeric PD‑1 receptor redirects primary T cells against childhood solid tumors but not to PD‑1 ligand‑positive CD80‑coexpressing cells

Chansu Shin, Masaru Imamura, Yasushi Kasahara, Yuko Suzuki, Minori Baba, Nobuhiro Kubo, Ryosuke Hosokai, Haruko Iwabuchi, Yudai Murayama, Hiroyuki Kawashima, Akira Ogose, Keichiro Mihara, Akihiko Saitoh, Chihaya Imai

Article Number: 243
Published online on: 07 July 2025
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