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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2006 Volume 15 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

S100P calcium-binding protein expression is associated with high-risk proliferative lesions of the breast

Ana Paula Torres Schor, Filomena Marino Carvalho, Cláudio Kemp, Ismael D.C.G. Silva, Jose Russo
Pages: 3-6
Published online on: 01 January 2006

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Article

Combination celecoxib and temozolomide in C6 rat glioma orthotopic model

Seok-Gu Kang, Jong Soo Kim, Kwan Park, Morris D. Groves, Do-Hyun Nam
Pages: 7-13
Published online on: 01 January 2006

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Article

Microcirculation patterns in different stages of melanoma growth

Shiwu Zhang, Hua Guo, Danfang Zhang, Wenzhi Zhang, Xiulan Zhao, Zhiyong Ren, Baocun Sun
Pages: 15-20
Published online on: 01 January 2006

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Article

Clinical implications of expression of cyclooxygenase-2 related to angiogenesis in ovarian cancer

Jiro Fujimoto, Hiroshi Toyoki, Hideki Sakaguchi, Israt Jahan, Syed Mahfuzul Alam, Teruhiko Tamaya
Pages: 21-25
Published online on: 01 January 2006

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Article

Epigenetic silencing of the sulfotransferase 1A1 gene by hypermethylation in breast tissue

Min Sook Kwon, Sun Jung Kim, Su-Young Lee, Jeong Hae Jeong, Eun Sook Lee, Han-Sung Kang
Pages: 27-32
Published online on: 01 January 2006

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Article

Temporal cDNA microarray analysis of gene expression in human hepatocellular carcinoma upon radiation exposure

Jaemin Jeong, Su-Jin Hong, Yeun-Jin Ju, Bu-Yeo Kim, Myung-Jin Park, Tae-Hwan Kim, Chul-In Park, Kang-Yell Choi, Myung-Haeng Cho, Sang-Hoon Kim, Hansoo Lee, Kee-Ho Lee
Pages: 33-48
Published online on: 01 January 2006

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Article

Plasma membrane Ca2+ ATPase isoform 1 down-regulated in human oral cancer

Kengo Saito, Katsuhiro Uzawa, Yosuke Endo, Yoshikuni Kato, Dai Nakashima, Katsunori Ogawara, Masashi Shiba, Hiroki Bukawa, Hidetaka Yokoe, Hideki Tanzawa
Pages: 49-55
Published online on: 01 January 2006

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Article

Identification of differential gene expression between intestinal and diffuse gastric cancer using cDNA microarray

Chi-Ming Wu, Yun-Shien Lee, Tzu-Hao Wang, Li-Yu Lee, Wei-Hsiang Kong, En-Shih Chen, Min-Li Wei, Ying Liang, Tsann-Long Hwang
Pages: 57-64
Published online on: 01 January 2006

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Article

Comparison of HER2 gene amplification assessed by fluorescence in situ hybridization and HER2 protein expression assessed by immunohistochemistry in gastric cancer

Tomonori Yano, Toshihiko Doi, Atsushi Ohtsu, Narikazu Boku, Kaoru Hashizume, Mamoru Nakanishi, Atsushi Ochiai
Pages: 65-71
Published online on: 01 January 2006

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Article

Effect of Vinorelbine on cell growth and apoptosis induction in human osteosarcoma in vitro

Laura Roncuzzi, Gianpiero Marti, Daniela Baiocchi, Rosalba Del Coco, Stefania Cocchi, Anna Gasperi-Campani
Pages: 73-77
Published online on: 01 January 2006

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Article

Antiangiogenic agent SU6668 suppresses the tumor growth of xenografted A-431 cells

Takeshi Nakamura, Soji Ozawa, Yuko Kitagawa, Masakazu Ueda, Tetsuro Kubota, Masaki Kitajima
Pages: 79-83
Published online on: 01 January 2006

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Article

nm23 is expressed in reactive mesothelium and is not useful for detection of malignant cells in serous effusions

Robert L. Zimmerman, Franz Fogt
Pages: 85-88
Published online on: 01 January 2006

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Article

Rb-loss is associated with high malignancy in chondrosarcoma

M. Röpke, C. Boltze, B. Meyer, H. W. Neumann, A. Roessner, R. Schneider-Stock
Pages: 89-95
Published online on: 01 January 2006

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Article

Combined modality therapy of gemcitabine and irradiation on human glioma spheroids derived from cell lines and biopsy tissue

Fabian Fehlauer, Martina Muench, Ernst J. Smid, Ben Slotman, Eckhard Richter, Paul Van der Valk, Peter Sminia
Pages: 97-105
Published online on: 01 January 2006

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Article

Phenothiazines induce apoptosis in a B16 mouse melanoma cell line and attenuate in vivo melanoma tumor growth

Irit Gil-Ad, Biana Shtaif, Yechiel Levkovitz, Jardena Nordenberg, Michal Taler, Inna Korov, Abraham Weizman
Pages: 107-112
Published online on: 01 January 2006

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Article

Inhibition of proliferative and invasive capacities of breast cancer cells by arginine-glycine-aspartic acid peptide in vitro

Wanhua Yang, Li Meng, Hui Wang, Rui Chen, Rui Wang, Xiangyi Ma, Gang Xu, Jianfeng Zhou, Shixuan Wang, Yunping Lu, Ding Ma
Pages: 113-117
Published online on: 01 January 2006

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Article

L-carnitine inhibits apoptotic DNA fragmentation induced by a new spin-labeled derivative of podophyllotoxin via caspase-3 in Raji cells

She-Ning Qi, Zhi-Feng Zhang, Zhen-Yun Wang, Akira Yoshida, Takanori Ueda
Pages: 119-122
Published online on: 01 January 2006

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Article

A phase I trial of docetaxel and vinorelbine in patients with advanced non-small cell lung cancer

Ramaswamy Govindan, Wan-Teck Lim, Matthew A. Arquette, Sherry A. Goodner, Carole L. Fears, Joanne E. Mortimer, Paula M. Fracasso
Pages: 123-127
Published online on: 01 January 2006

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Article

Epigenetic inactivation of the RUNX3 gene in lung cancer

Koji Sato, Yoshio Tomizawa, Hironobu Iijima, Ryusei Saito, Tamotsu Ishizuka, Takashi Nakajima, Masatomo Mori
Pages: 129-135
Published online on: 01 January 2006

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Article

Expression and adhesive activity of SC1, an Ig superfamily cell adhesion molecule, in sporadic nephroblastomas of chicken

Yasuhiro Tsukamoto, Takashi Namikawa, Ryouta Tatesaki, Takao Kotani, Hideaki Tanaka
Pages: 137-141
Published online on: 01 January 2006

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Article

Single or multiple HPV types in cervical cancer and associated metastases

Marco Ciotti, Pierpaolo Paba, Daniela Bonifacio, Luigi Di Bonito, Arrigo Benedetto, Cartesio Favalli
Pages: 143-148
Published online on: 01 January 2006

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Article

p53 enhances the Δ-24 conditionally replicative adenovirus anti-glioma effect

P. G. Mitlianga, C. Sioka, G. Vartholomatos, A. Goussia, K. Polyzoidis, J. S. Rao, A. P. Kyritsis
Pages: 149-153
Published online on: 01 January 2006

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Article

Amelioration of carcinogenesis and tumor growth in the rat liver by combination of vitamin K2 and angiotensin-converting enzyme inhibitor via anti-angiogenic activities

Hitoshi Yoshiji, Shigeki Kuriyama, Ryuichi Noguchi, Junichi Yoshii, Yasuhide Ikenaka, Koji Yanase, Tadashi Namisaki, Mitsuteru Kitade, Masaharu Yamazaki, Takemi Akahane, Kiyoshi Asada, Tatsuhito Tsujimoto, Masahito Uemura, Hiroshi Fukui
Pages: 155-159
Published online on: 01 January 2006

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Article

The relationship between 5-fluorouracil sensitivity and single nucleotide polymorphisms of the orotate phosphoribosyl transferase gene in colorectal cancer

Masayuki Kitajima, Naohito Takita, Masaki Hata, Tsutomu Maeda, Kazuhiro Sakamoto, Toshiki Kamano, Takumi Ochiai
Pages: 161-165
Published online on: 01 January 2006

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Article

Aberrant promoter methylation of EDNRB in lung cancer in Taiwan

Shu-Chen Chen, Chia-Yu Lin, Ya-Hui Chen, Hsin-Yuan Fang, Ching-Yuan Cheng, Chih-Wen Chang, Ruei-A Chen, Hui-Lung Tai, Chien-Hsing Lee, Ming-Chih Chou, Torng-Sen Lin, Li-Sung Hsu
Pages: 167-172
Published online on: 01 January 2006

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Article

Molecular cloning of rHAUSP encoding a deubiquitinating enzyme in rat testis

Kwang-Hyun Baek, Hye-Jin Lee, Myung-Sun Kim, Yong-Soo Kim, Minu Seong, Eung-Ji Lee, Min-Young Lee
Pages: 173-177
Published online on: 01 January 2006

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Review

Potential prognostic and therapeutic roles for cytokines in breast cancer (Review)

V. S.R. Rao, C. E. Dyer, J. K.A. Jameel, P. J. Drew, J. Greenman
Pages: 179-185
Published online on: 01 January 2006

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Article

SAHA, a HDAC inhibitor, has profound anti-growth activity against non-small cell lung cancer cells

Naoki Komatsu, Norihiko Kawamata, Seisho Takeuchi, Dong Yin, Wenwen Chien, Carl W. Miller, H. Phillip Koeffler
Pages: 187-191
Published online on: 01 January 2006

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Article

Real-time RT-PCR analysis of human histidine decarboxylase, a new marker for several types of leukemia and cancer

Esther Melgarejo, Miguel Ángel Medina, José Carlos Paz, Francisca Sánchez-Jiménez, José Luis Urdiales
Pages: 193-197
Published online on: 01 January 2006

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Article

The influence of CD44v3-v10 on adhesion, invasion and MMP-14 expression in prostate cancer cells

G. M. Harrison, G. Davies, T. A. Martin, M. D. Mason, W. G. Jiang
Pages: 199-206
Published online on: 01 January 2006

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Article

Down-regulation of MLL-AF9, MLL and MYC expression is not obligatory for monocyte-macrophage maturation in AML-M5 cell lines carrying t(9;11)(p22;q23)

Vincenzo Martino, Roberto Tonelli, Luca Montemurro, Monica Franzoni, Flora Marino, Raffaella Fazzina, Andrea Pession
Pages: 207-211
Published online on: 01 January 2006

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Article

Prognostic value of static cytometry in transitional cell carcinoma of the bladder: Recurrence rate and survival in a group of patients at 10 years follow-up

Tommaso Cai, Edoardo Margallo, Gabriella Nesi, Gianluca Giubilei, Michelangelo Rizzo, Riccardo Bartoletti
Pages: 213-219
Published online on: 01 January 2006

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Article

Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in human breast cancer

Shao Ying Li, Minna Rong, Barry Iacopetta
Pages: 221-225
Published online on: 01 January 2006

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Article

Histone deacetylase inhibition by valproic acid down-regulates c-FLIP/CASH and sensitizes hepatoma cells towards CD95- and TRAIL receptor-mediated apoptosis and chemotherapy

M. Schuchmann, H. Schulze-Bergkamen, B. Fleischer, J. M. Schattenberg, J. Siebler, A. Weinmann, A. Teufel, M. Wörns, T. Fischer, S. Strand, A. W. Lohse, P. R. Galle
Pages: 227-230
Published online on: 01 January 2006

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Article

Antiestrogens modulate MT1 melatonin receptor expression in breast and ovarian cancer cell lines

Oliver Treeck, Chandana Haldar, Olaf Ortmann
Pages: 231-235
Published online on: 01 January 2006

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Article

Phase II study of melphalan as a single-agent infused over a 24-hour period with individual adapted dosing in patients with recurrent epithelial ovarian cancer

Philippe Mougenot, Michel Fabbro, Françoise Bressolle, Damien Pouessel, Stephane Culine, Frederic Pinguet
Pages: 237-241
Published online on: 01 January 2006

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Article

Correlation between DNA ploidy by flow cytometry and chromosome 3 aberration in oral squamous cell carcinoma

Joerg Hemmer, Klaus Kraft, Willie F.P. Van Heerden
Pages: 243-246
Published online on: 01 January 2006

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Article

Polymorphisms of ADPRT Val762Ala and XRCC1 Arg399Glu and risk of breast cancer in Chinese women: A case control analysis

Xiangjun Zhai, Jiyong Liu, Zhibin Hu, Shui Wang, Jianwei Qing, Xuechen Wang, Guangfu Jin, Jun Gao, Xinru Wang, Hongbing Shen
Pages: 247-252
Published online on: 01 January 2006

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Article

Clinical utility of serum macrophage migration inhibitory factor in men with prostate cancer as a novel biomarker of detection and disease progression

Mototsugu Muramaki, Hideaki Miyake, Yuji Yamada, Isao Hara
Pages: 253-257
Published online on: 01 January 2006

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Article

Genomic instability analysis of urine sediment versus tumor tissue in transitional cell carcinoma of the urinary bladder

Jacek Turyn, Marcin Matuszewski, Beata Schlichtholz
Pages: 259-265
Published online on: 01 January 2006

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Article

High energy shock waves enhance the cytotoxic effect of doxorubicin and methotrexate to human osteosarcoma cell lines

Alessandra Palmero, Massimo Berger, Claudio Venturi, Ivana Ferrero, Deborah Rustichelli, Laura Berta, Roberto Frairia, Enrico Madon, Franca Fagioli
Pages: 267-273
Published online on: 01 January 2006

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Article

Anti-proliferative effect of horehound leaf and wild cherry bark extracts on human colorectal cancer cells

Kiyoshi Yamaguchi, Jason L. Liggett, Nam-Cheol Kim, Seung Joon Baek
Pages: 275-281
Published online on: 01 January 2006

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Article

Hsp27 may allow prediction of the response to single-agent vinorelbine chemotherapy in non-small cell lung cancer

Helen K. Berrieman, Lynn Cawkwell, Sara L. O'Kane, Laura Smith, Michael J. Lind
Pages: 283-286
Published online on: 01 January 2006

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
Article Number: 145
Published online on: 10 June 2026

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Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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