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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2007 Volume 17 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Role of the STK15 Phe31Ile polymorphism in renal cell carcinoma

Christine G. Hammerschmied, Robert Stoehr, Bernhard Walter, Wolf F. Wieland, Arndt Hartmann, Hagen Blaszyk, Stefan Denzinger
Pages: 3-7
Published online on: 01 January 2007

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Article

Mutational analysis of the BRAF gene in colorectal mucinous carcinoma in association with histological configuration

Naoto Yoshitake, Shigehiko Fujii, Kenichiroh Mukawa, Keiichi Tominaga, Hirokazu Fukui, Kazuhito Ichikawa, Shigeki Tomita, Yuko Ono, Yasuo Imai, Akira Terano, Hideyuki Hiraishi, Takahiro Fujimori
Pages: 9-15
Published online on: 01 January 2007

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Article

Constitutive phosphorylation of Janus kinase 2 in the GL15 glioblastoma derived human cell line

Miriam Sciaccaluga, Gian Luigi Gianfranceschi, Simone Rocco, Giovanni Germano, Giovanni Roti, Paolo Gorello, Roberta La Starza, Emilia Castigli
Pages: 17-23
Published online on: 01 January 2007

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Article

Cell proliferation and tumor formation induced by eserine, an acetylcholinesterase inhibitor, in rat mammary gland

G. M. Calaf, E. Parra, F. Garrido
Pages: 25-33
Published online on: 01 January 2007

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Article

Altered p-JAK1 expression is associated with estrogen receptor status in breast infiltrating ductal carcinoma

Y. T. Yeh, F. Ou-Yang, I. F. Chen, S. F. Yang, J. H. Su, M. F. Hou, S. S. Yuan
Pages: 35-39
Published online on: 01 January 2007

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Article

Relationship of aberrant DNA hypermethylation of CHFR with sensitivity to taxanes in endometrial cancer

Megumi Yanokura, Kouji Banno, Makiko Kawaguchi, Nobumaru Hirao, Akira Hirasawa, Nobuyuki Susumu, Katsumi Tsukazaki, Daisuke Aoki
Pages: 41-48
Published online on: 01 January 2007

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Article

Pinkus tumor may originate from intraepidermal eccrine ducts and proliferate in the dermis

Ichiro Kurokawa, Tomoya Yokoyama, Keisuke Nishimura, Arata Hakamada, Ken-ichi Isoda, Kei-ichi Yamanaka, Airo Tsubura, Hitoshi Mizutani
Pages: 49-54
Published online on: 01 January 2007

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Article

Low selection of preneoplastic hepatocytes after treatment with the 2-acetylaminofluorene diet-partial hepatectomy regimen in the liver of hepatocarcinogenesis-resistant DRH strain rats

Koji Imai, Masahiro Yamamoto, Hiroki Tanaka, Norikazu Hashimoto, Masaaki Miyakoshi, Satoshi Honmou, Masumi Yoshie, Susumu Tamakawa, Yuji Yaginuma, Shinichi Kasai, Katsuhiro Ogawa
Pages: 55-60
Published online on: 01 January 2007

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Article

Angiogenesis in gastric cancer: Importance of the thymidine phosphorylase expression of cancer cells as an angiogenic factor

Hye Seung Han, Tae Sook Hwang
Pages: 61-65
Published online on: 01 January 2007

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Article

Establishment of nude mouse transplantable model of a human adenoid cystic carcinoma of the oral floor showing metastasis to the lymph node and lung

Susumu Hashitani, Masahiro Urade, Yusuke Zushi, Emi Segawa, Shin Okui, Kazunari Sakurai
Pages: 67-72
Published online on: 01 January 2007

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Article

Frequent genetic alterations and reduced expression of the Axin1 gene in oral squamous cell carcinoma: Involvement in tumor progression and metastasis

Chuan-Xiang Zhou, Yan Gao
Pages: 73-79
Published online on: 01 January 2007

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Article

Clinical significance of metabotropic glutamate receptor 5 expression in oral squamous cell carcinoma

So-Yeon Park, Seoung-Ae Lee, In-Hee Han, Byong-Chul Yoo, Seung-Hoon Lee, Jo-Yong Park, In-Ho Cha, Jin Kim, Sung-Weon Choi
Pages: 81-87
Published online on: 01 January 2007

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Article

Geldanamycin destabilizes HER2 tyrosine kinase and suppresses Wnt/β-catenin signaling in HER2 overexpressing human breast cancer cells

Ke Wang, Qingyong Ma, Yu Ren, Jianjun He, Yong Zhang, Yunfeng Zhang, Wuke Chen
Pages: 89-96
Published online on: 01 January 2007

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Article

Expression of the inhibin/activin subunits (-α, -βA and -βB) in normal and carcinogenic endometrial tissue: Possible immunohistochemical differentiation markers

Silvia Worbs, Naim Shabani, Doris Mayr, Andrea Gingelmaier, Antonios Makrigiannakis, Christina Kuhn, Udo Jeschke, Markus S. Kupka, Klaus Friese, Ioannis Mylonas
Pages: 97-104
Published online on: 01 January 2007

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Article

Malignant transformation of the cultured human normal biliary tract epithelial cells induced by hepatitis C virus core protein

Ru-Fu Chen, Zhi-Hua Li, Ran-Yi Liu, Xian-He Kong, Qi-Bin Tang, Jie Wang
Pages: 105-110
Published online on: 01 January 2007

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Article

The identification of a novel alternatively spliced form of the MBD4 DNA glycosylase

Rhiannon M. Owen, Rachael D. Baker, Scott Bader, Malcolm G. Dunlop, Iain D. Nicholl
Pages: 111-116
Published online on: 01 January 2007

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Article

Knock-down of P-glycoprotein reverses taxol resistance in ovarian cancer multicellular spheroids

Hui Xing, Shixuan Wang, Danhui Weng, Gang Chen, Xiaokui Yang, Jianfeng Zhou, Gang Xu, Yunpin Lu, Ding Ma
Pages: 117-122
Published online on: 01 January 2007

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Article

Frequent loss of PDCD4 expression in human glioma: Possible role in the tumorigenesis of glioma

Fei Gao, Pin Zhang, Chuixian Zhou, Jianfeng Li, Qun Wang, Faliang Zhu, Chunhong Ma, Wensheng Sun, Lining Zhang
Pages: 123-128
Published online on: 01 January 2007

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Article

Induction of anti-tumor immunity by lyophilized myeloma cells secreting GM-CSF

Sheng Wu, Dawen Yuan, Jian-Ning Liu, Xiang-Yang Tan
Pages: 129-133
Published online on: 01 January 2007

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Article

Mutational analysis of Chk1, Chk2, Apaf1 and Rb1 in human malignant melanoma cell lines

Thilo Papp, Annett Niemetz, Nils Dosdahl, Krishan Kumar, Dietmar Schiffmann
Pages: 135-140
Published online on: 01 January 2007

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Article

Functional advantage of NPC-related V-val subtype of Epstein-Barr virus nuclear antigen 1 compared with prototype in epithelial cell line

Shi-Juan Mai, Tadamasa Ooka, Da-Jiang Li, Mu-Sheng Zeng, Ri-Cheng Jiang, Xing-Juan Yu, Ru-Hua Zhang, Shi-Ping Chen, Yi-Xin Zeng
Pages: 141-146
Published online on: 01 January 2007

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Article

Expression of angiogenic factors in childhood B-cell precursor acute lymphoblastic leukemia

Daniel Stachel, Michael Albert, Rita Meilbeck, Marios Paulides, Irene Schmid
Pages: 147-152
Published online on: 01 January 2007

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Article

Cyclophosphamide augments the anti-tumor efficacy of uracil and tegafur by inhibiting dihydropyrimidine dehydrogenase

Yoshinori Nio, Chikage Iguchi, Hiroshi Kodama, Masayuki Itakura, Koji Hashimoto, Makoto Koike, Tomoko Toga, Riruke Maruyama, Masakazu Fukushima
Pages: 153-159
Published online on: 01 January 2007

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Article

Neutrophil elastase induces cell proliferation and migration by the release of TGF-α, PDGF and VEGF in esophageal cell lines

Yoshiyuki Wada, Kazuhiro Yoshida, Yasuhiro Tsutani, Hideaki Shigematsu, Mamoru Oeda, Yuichi Sanada, Takahisa Suzuki, Hirozumi Mizuiri, Yoichi Hamai, Kazuaki Tanabe, Kei Ukon, Jun Hihara
Pages: 161-167
Published online on: 01 January 2007

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Article

Etodolac, a selective cyclooxygenase-2 inhibitor, induces apoptosis by activating caspases in human malignant rhabdoid tumor cells (FRTK-1)

Michiyuki Hakozaki, Hiroshi Hojo, Shinichi Kikuchi, Masafumi Abe
Pages: 169-173
Published online on: 01 January 2007

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Article

Phytosphingosine in combination with TRAIL sensitizes cancer cells to TRAIL through synergistic up-regulation of DR4 and DR5

Soon-Young Choi, Min-Jung Kim, Hee Yong Chung, Su-Jae Lee, Young-Ju Jang
Pages: 175-184
Published online on: 01 January 2007

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Article

The synergistic apoptotic effects of thiophenfurin, an inosine monophosphate dehydrogenase inhibitor, in combination with retinoids in HL60 cells

Maria Meli, Manlio Tolomeo, Mario Grifantini, Palmarisa Franchetti, Loredana Cappellacci, Daniele Simoni, Francesco P. Invidiata, Stefania Aiello, Luisa Dusonchet
Pages: 185-192
Published online on: 01 January 2007

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Article

Triplet repeat instability correlates with dinucleotide instability in primary breast cancer

Claudia Pizzi, Massimo Di Maio, Santa Daniele, Paolo Mastranzo, Ilaria Spagnoletti, Gennaro Limite, Guido Pettinato, Antonella Monticelli, Sergio Cocozza, Alma Contegiacomo
Pages: 193-199
Published online on: 01 January 2007

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Article

Phenoxazine derivatives induce caspase-independent cell death in human glioblastoma cell lines, A-172 and U-251 MG

Ken Shirato, Kazuhiko Imaizumi, Akihisa Abe, Akio Tomoda
Pages: 201-208
Published online on: 01 January 2007

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Article

Enhanced lung cancer cell killing by the combination of selenium and ionizing radiation

Sun Hye Shin, Mi Jin Yoon, Mira Kim, Jong-Il Kim, Su-Jae Lee, Yun-Sil Lee, Sangwoo Bae
Pages: 209-216
Published online on: 01 January 2007

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Article

Biological and clinical significance of MMP-2, MMP-9, TIMP-1 and TIMP-2 in non-small cell lung cancer

Pilar Iniesta, Alberto Morán, Carmen De Juan, Ana Gómez, Florentino Hernando, Cristina García-Aranda, Cristina Frías, Antonio Díaz-López, Francisco-Javier Rodríguez-Jiménez, Jose-Luis Balibrea, Manuel Benito
Pages: 217-223
Published online on: 01 January 2007

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Article

Induction of apoptosis in an estrogen-responsive mouse Leydig tumor cell by leukotriene

H. G. Goto, Y. Nishizawa, H. Katayama, T. Murashima, M. Yamasaki, Y. Tanigaki, S. Kimura, S. Fushiki
Pages: 225-232
Published online on: 01 January 2007

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Article

Effects of 6-(methylsulfinyl)hexyl isothiocyanate on cyclooxygenase-2 expression induced by lipopolysaccharide, interferon-γ and 12-O-tetradecanoylphorbol-13-acetate

Takuhiro Uto, Makoto Fujii, De-Xing Hou
Pages: 233-238
Published online on: 01 January 2007

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Article

Role of the tumor microenvironment in the activity and expression of the p-glycoprotein in human colon carcinoma cells

Christopher Lotz, Debra K. Kelleher, Birgit Gassner, Michael Gekle, Peter Vaupel, Oliver Thews
Pages: 239-244
Published online on: 01 January 2007

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Review

Protective autoimmunity in cancer (Review)

E. Toubi, Y. Shoenfeld
Pages: 245-251
Published online on: 01 January 2007

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Article

Neoadjuvant 5-fluorouracil, epirubicin and cyclophosphamide chemotherapy followed by docetaxel in refractory patients with locally advanced breast cancer

W. Heller, D. Mazhar, R. Ward, H. D. Sinnett, C. Lowdell, R. Phillips, S. Shousha, A. Fayaz, C. Palmieri, R. C. Coombes
Pages: 253-259
Published online on: 01 January 2007

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Article

Chromosomal aberrations detected by comparative genomic hybridization predict outcome in patients with colorectal carcinoma

Xiu-Ping Liu, Shigeto Kawauchi, Atsunori Oga, Toshihiko Sato, Kenzou Ikemoto, Eiichi Ikeda, Kohsuke Sasaki
Pages: 261-267
Published online on: 01 January 2007

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
Article Number: 145
Published online on: 10 June 2026

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Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
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Review Open Access

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Expression of Concern Open Access

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Article Open Access

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