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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2007 Volume 17 Issue 1

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Role of the STK15 Phe31Ile polymorphism in renal cell carcinoma

Christine G. Hammerschmied, Robert Stoehr, Bernhard Walter, Wolf F. Wieland, Arndt Hartmann, Hagen Blaszyk, Stefan Denzinger
Pages: 3-7
Published online on: 01 January 2007

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Article

Mutational analysis of the BRAF gene in colorectal mucinous carcinoma in association with histological configuration

Naoto Yoshitake, Shigehiko Fujii, Kenichiroh Mukawa, Keiichi Tominaga, Hirokazu Fukui, Kazuhito Ichikawa, Shigeki Tomita, Yuko Ono, Yasuo Imai, Akira Terano, Hideyuki Hiraishi, Takahiro Fujimori
Pages: 9-15
Published online on: 01 January 2007

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Article

Constitutive phosphorylation of Janus kinase 2 in the GL15 glioblastoma derived human cell line

Miriam Sciaccaluga, Gian Luigi Gianfranceschi, Simone Rocco, Giovanni Germano, Giovanni Roti, Paolo Gorello, Roberta La Starza, Emilia Castigli
Pages: 17-23
Published online on: 01 January 2007

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Article

Cell proliferation and tumor formation induced by eserine, an acetylcholinesterase inhibitor, in rat mammary gland

G. M. Calaf, E. Parra, F. Garrido
Pages: 25-33
Published online on: 01 January 2007

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Article

Altered p-JAK1 expression is associated with estrogen receptor status in breast infiltrating ductal carcinoma

Y. T. Yeh, F. Ou-Yang, I. F. Chen, S. F. Yang, J. H. Su, M. F. Hou, S. S. Yuan
Pages: 35-39
Published online on: 01 January 2007

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Article

Relationship of aberrant DNA hypermethylation of CHFR with sensitivity to taxanes in endometrial cancer

Megumi Yanokura, Kouji Banno, Makiko Kawaguchi, Nobumaru Hirao, Akira Hirasawa, Nobuyuki Susumu, Katsumi Tsukazaki, Daisuke Aoki
Pages: 41-48
Published online on: 01 January 2007

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Article

Pinkus tumor may originate from intraepidermal eccrine ducts and proliferate in the dermis

Ichiro Kurokawa, Tomoya Yokoyama, Keisuke Nishimura, Arata Hakamada, Ken-ichi Isoda, Kei-ichi Yamanaka, Airo Tsubura, Hitoshi Mizutani
Pages: 49-54
Published online on: 01 January 2007

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Article

Low selection of preneoplastic hepatocytes after treatment with the 2-acetylaminofluorene diet-partial hepatectomy regimen in the liver of hepatocarcinogenesis-resistant DRH strain rats

Koji Imai, Masahiro Yamamoto, Hiroki Tanaka, Norikazu Hashimoto, Masaaki Miyakoshi, Satoshi Honmou, Masumi Yoshie, Susumu Tamakawa, Yuji Yaginuma, Shinichi Kasai, Katsuhiro Ogawa
Pages: 55-60
Published online on: 01 January 2007

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Article

Angiogenesis in gastric cancer: Importance of the thymidine phosphorylase expression of cancer cells as an angiogenic factor

Hye Seung Han, Tae Sook Hwang
Pages: 61-65
Published online on: 01 January 2007

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Article

Establishment of nude mouse transplantable model of a human adenoid cystic carcinoma of the oral floor showing metastasis to the lymph node and lung

Susumu Hashitani, Masahiro Urade, Yusuke Zushi, Emi Segawa, Shin Okui, Kazunari Sakurai
Pages: 67-72
Published online on: 01 January 2007

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Article

Frequent genetic alterations and reduced expression of the Axin1 gene in oral squamous cell carcinoma: Involvement in tumor progression and metastasis

Chuan-Xiang Zhou, Yan Gao
Pages: 73-79
Published online on: 01 January 2007

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Article

Clinical significance of metabotropic glutamate receptor 5 expression in oral squamous cell carcinoma

So-Yeon Park, Seoung-Ae Lee, In-Hee Han, Byong-Chul Yoo, Seung-Hoon Lee, Jo-Yong Park, In-Ho Cha, Jin Kim, Sung-Weon Choi
Pages: 81-87
Published online on: 01 January 2007

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Article

Geldanamycin destabilizes HER2 tyrosine kinase and suppresses Wnt/β-catenin signaling in HER2 overexpressing human breast cancer cells

Ke Wang, Qingyong Ma, Yu Ren, Jianjun He, Yong Zhang, Yunfeng Zhang, Wuke Chen
Pages: 89-96
Published online on: 01 January 2007

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Article

Expression of the inhibin/activin subunits (-α, -βA and -βB) in normal and carcinogenic endometrial tissue: Possible immunohistochemical differentiation markers

Silvia Worbs, Naim Shabani, Doris Mayr, Andrea Gingelmaier, Antonios Makrigiannakis, Christina Kuhn, Udo Jeschke, Markus S. Kupka, Klaus Friese, Ioannis Mylonas
Pages: 97-104
Published online on: 01 January 2007

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Article

Malignant transformation of the cultured human normal biliary tract epithelial cells induced by hepatitis C virus core protein

Ru-Fu Chen, Zhi-Hua Li, Ran-Yi Liu, Xian-He Kong, Qi-Bin Tang, Jie Wang
Pages: 105-110
Published online on: 01 January 2007

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Article

The identification of a novel alternatively spliced form of the MBD4 DNA glycosylase

Rhiannon M. Owen, Rachael D. Baker, Scott Bader, Malcolm G. Dunlop, Iain D. Nicholl
Pages: 111-116
Published online on: 01 January 2007

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Article

Knock-down of P-glycoprotein reverses taxol resistance in ovarian cancer multicellular spheroids

Hui Xing, Shixuan Wang, Danhui Weng, Gang Chen, Xiaokui Yang, Jianfeng Zhou, Gang Xu, Yunpin Lu, Ding Ma
Pages: 117-122
Published online on: 01 January 2007

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Article

Frequent loss of PDCD4 expression in human glioma: Possible role in the tumorigenesis of glioma

Fei Gao, Pin Zhang, Chuixian Zhou, Jianfeng Li, Qun Wang, Faliang Zhu, Chunhong Ma, Wensheng Sun, Lining Zhang
Pages: 123-128
Published online on: 01 January 2007

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Article

Induction of anti-tumor immunity by lyophilized myeloma cells secreting GM-CSF

Sheng Wu, Dawen Yuan, Jian-Ning Liu, Xiang-Yang Tan
Pages: 129-133
Published online on: 01 January 2007

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Article

Mutational analysis of Chk1, Chk2, Apaf1 and Rb1 in human malignant melanoma cell lines

Thilo Papp, Annett Niemetz, Nils Dosdahl, Krishan Kumar, Dietmar Schiffmann
Pages: 135-140
Published online on: 01 January 2007

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Article

Functional advantage of NPC-related V-val subtype of Epstein-Barr virus nuclear antigen 1 compared with prototype in epithelial cell line

Shi-Juan Mai, Tadamasa Ooka, Da-Jiang Li, Mu-Sheng Zeng, Ri-Cheng Jiang, Xing-Juan Yu, Ru-Hua Zhang, Shi-Ping Chen, Yi-Xin Zeng
Pages: 141-146
Published online on: 01 January 2007

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Article

Expression of angiogenic factors in childhood B-cell precursor acute lymphoblastic leukemia

Daniel Stachel, Michael Albert, Rita Meilbeck, Marios Paulides, Irene Schmid
Pages: 147-152
Published online on: 01 January 2007

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Article

Cyclophosphamide augments the anti-tumor efficacy of uracil and tegafur by inhibiting dihydropyrimidine dehydrogenase

Yoshinori Nio, Chikage Iguchi, Hiroshi Kodama, Masayuki Itakura, Koji Hashimoto, Makoto Koike, Tomoko Toga, Riruke Maruyama, Masakazu Fukushima
Pages: 153-159
Published online on: 01 January 2007

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Article

Neutrophil elastase induces cell proliferation and migration by the release of TGF-α, PDGF and VEGF in esophageal cell lines

Yoshiyuki Wada, Kazuhiro Yoshida, Yasuhiro Tsutani, Hideaki Shigematsu, Mamoru Oeda, Yuichi Sanada, Takahisa Suzuki, Hirozumi Mizuiri, Yoichi Hamai, Kazuaki Tanabe, Kei Ukon, Jun Hihara
Pages: 161-167
Published online on: 01 January 2007

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Article

Etodolac, a selective cyclooxygenase-2 inhibitor, induces apoptosis by activating caspases in human malignant rhabdoid tumor cells (FRTK-1)

Michiyuki Hakozaki, Hiroshi Hojo, Shinichi Kikuchi, Masafumi Abe
Pages: 169-173
Published online on: 01 January 2007

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Article

Phytosphingosine in combination with TRAIL sensitizes cancer cells to TRAIL through synergistic up-regulation of DR4 and DR5

Soon-Young Choi, Min-Jung Kim, Hee Yong Chung, Su-Jae Lee, Young-Ju Jang
Pages: 175-184
Published online on: 01 January 2007

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Article

The synergistic apoptotic effects of thiophenfurin, an inosine monophosphate dehydrogenase inhibitor, in combination with retinoids in HL60 cells

Maria Meli, Manlio Tolomeo, Mario Grifantini, Palmarisa Franchetti, Loredana Cappellacci, Daniele Simoni, Francesco P. Invidiata, Stefania Aiello, Luisa Dusonchet
Pages: 185-192
Published online on: 01 January 2007

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Article

Triplet repeat instability correlates with dinucleotide instability in primary breast cancer

Claudia Pizzi, Massimo Di Maio, Santa Daniele, Paolo Mastranzo, Ilaria Spagnoletti, Gennaro Limite, Guido Pettinato, Antonella Monticelli, Sergio Cocozza, Alma Contegiacomo
Pages: 193-199
Published online on: 01 January 2007

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Article

Phenoxazine derivatives induce caspase-independent cell death in human glioblastoma cell lines, A-172 and U-251 MG

Ken Shirato, Kazuhiko Imaizumi, Akihisa Abe, Akio Tomoda
Pages: 201-208
Published online on: 01 January 2007

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Article

Enhanced lung cancer cell killing by the combination of selenium and ionizing radiation

Sun Hye Shin, Mi Jin Yoon, Mira Kim, Jong-Il Kim, Su-Jae Lee, Yun-Sil Lee, Sangwoo Bae
Pages: 209-216
Published online on: 01 January 2007

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Article

Biological and clinical significance of MMP-2, MMP-9, TIMP-1 and TIMP-2 in non-small cell lung cancer

Pilar Iniesta, Alberto Morán, Carmen De Juan, Ana Gómez, Florentino Hernando, Cristina García-Aranda, Cristina Frías, Antonio Díaz-López, Francisco-Javier Rodríguez-Jiménez, Jose-Luis Balibrea, Manuel Benito
Pages: 217-223
Published online on: 01 January 2007

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Article

Induction of apoptosis in an estrogen-responsive mouse Leydig tumor cell by leukotriene

H. G. Goto, Y. Nishizawa, H. Katayama, T. Murashima, M. Yamasaki, Y. Tanigaki, S. Kimura, S. Fushiki
Pages: 225-232
Published online on: 01 January 2007

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Article

Effects of 6-(methylsulfinyl)hexyl isothiocyanate on cyclooxygenase-2 expression induced by lipopolysaccharide, interferon-γ and 12-O-tetradecanoylphorbol-13-acetate

Takuhiro Uto, Makoto Fujii, De-Xing Hou
Pages: 233-238
Published online on: 01 January 2007

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Article

Role of the tumor microenvironment in the activity and expression of the p-glycoprotein in human colon carcinoma cells

Christopher Lotz, Debra K. Kelleher, Birgit Gassner, Michael Gekle, Peter Vaupel, Oliver Thews
Pages: 239-244
Published online on: 01 January 2007

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Review

Protective autoimmunity in cancer (Review)

E. Toubi, Y. Shoenfeld
Pages: 245-251
Published online on: 01 January 2007

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Article

Neoadjuvant 5-fluorouracil, epirubicin and cyclophosphamide chemotherapy followed by docetaxel in refractory patients with locally advanced breast cancer

W. Heller, D. Mazhar, R. Ward, H. D. Sinnett, C. Lowdell, R. Phillips, S. Shousha, A. Fayaz, C. Palmieri, R. C. Coombes
Pages: 253-259
Published online on: 01 January 2007

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Article

Chromosomal aberrations detected by comparative genomic hybridization predict outcome in patients with colorectal carcinoma

Xiu-Ping Liu, Shigeto Kawauchi, Atsunori Oga, Toshihiko Sato, Kenzou Ikemoto, Eiichi Ikeda, Kohsuke Sasaki
Pages: 261-267
Published online on: 01 January 2007

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Journal Cover
September-2026 Volume 56 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Polyphyllin II inhibits thyroid cancer progression by targeting HRH1 and suppressing Wnt/β‑catenin signaling

Jianwei Sun, Haifeng Liang, Yan Zhang, Ding Ding, Qian Xiang, Mengyang Zheng, Pengyue Zhang
Article Number: 163
Published online on: 23 July 2026

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Review Open Access

Multidimensional molecular mechanisms of drug resistance in breast cancer: Implications for clinical decision‑making and treatment strategies (Review)

Wenya Xu, Shiyao Kang, Shaochen Xin, Yanbin Wu, Yuan Zhao, Miaomiao Sheng
Article Number: 162
Published online on: 22 July 2026

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Review Open Access

XPO1: From basic research to clinical treatment (Review)

Changyan Yang, Jing Zhu, Xiang Zheng, Xiaochen Hou, Jiumei Zhao, Youfu Pan, Yu Tang
Article Number: 161
Published online on: 22 July 2026

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Retraction Open Access

[Retracted] Methylation and intratumoural heterogeneity of 14‑3‑3 σ in oral cancer

Ujjal Kumar Bhawal, Keiichi Tsukinoki, Tomonori Sasahira, Fuyuki Sato, Yusuke Mori, Noriko Muto, Masaru Sugiyama, Hiroki Kuniyasu
Article Number: 160
Published online on: 20 July 2026

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Article Open Access

M2‑TAM‑derived exosomal miR‑491‑3p modulates UBE2D3 and promotes the proliferation, migration and invasion of lung cancer cells

Qiang Zhang, Yungang Sun, Yu Zhuang, Shiwei Xu, Mengxu Yao, Siyang Jiao, Qi Wang, Feng Shao, Xiaoying Zhang
Article Number: 159
Published online on: 17 July 2026

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Correction Open Access

[Corrigendum] Emodin attenuated severe acute pancreatitis via the P2X ligand‑gated ion channel 7/NOD‑like receptor protein 3 signaling pathway

Qingkai Zhang, Xufeng Tao, Shilin Xia, Jialin Qu, Huiyi Song, Jianjun Liu, Hailong Li, Dong Shang
Article Number: 158
Published online on: 15 July 2026

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Article Open Access

TM6SF2 overexpression suppresses the proliferation and promotes apoptosis of human hepatocellular carcinoma cells

Ziyou Huai, Wanying Xue, Xinxiao Jin, Shiyu Peng, Wenqiang Xu, Shujing Li, Huanfeng Hao, Yuanyuan Wang
Article Number: 157
Published online on: 14 July 2026

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Correction Open Access

[Corrigendum] VDAC upregulation and αTAT1‑mediated α‑tubulin acetylation contribute to tanespimycin‑induced apoptosis in Calu‑1 cells

Qilin Wang, Xiangguo Liu
Article Number: 156
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells

Annamaria Spina, Luca Sorvillo, Emilio Chiosi, Antonietta Esposito, Francesca Di Maiolo, Luigi Sapio, Michele Caraglia, Silvio Naviglio
Article Number: 155
Published online on: 06 July 2026

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Article Open Access

Identification of RRM2 as a key regulator of malignant epithelial cells in gastric cancer through single‑cell transcriptomics

Xinzhen Cai, Yun He, Lili Kang, Dongli Zhou, Mengmeng Wang, Tianyu Ma
Article Number: 154
Published online on: 03 July 2026

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Article

Impact of WFDC2 on the biological functions of cervical cancer cells and the regulation of the ERK/NF‑κB signaling pathway

Yanping Zhang, Hongling Zou, Shufeng Deng, Lvling Zou, Mingzhu Xia, Limin Tao
Article Number: 153
Published online on: 01 July 2026

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyv Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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