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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July 2009 Volume 22 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Combination of p53 expression and p21 loss has an independent prognostic impact on sporadic colorectal cancer

Aurelia Noske, Sybille Lipka, Jan Budczies, Kathrin Müller, Christoph Loddenkemper, Heinz Johannes Buhr, Martin Kruschewski
Pages: 3-9
Published online on: 01 July 2009

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Article

Expression of 14-3-3σ in cervical squamous cell carcinomas: Relationship with clinical outcome

Ruth Holm, Tayeba Ali, Debbie H. Svendsrud, Jahn M. Nesland, Gunnar B. Kristensen, Heidi Lyng
Pages: 11-15
Published online on: 01 July 2009

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Article

Fluorescence diagnosis of lymph node metastasis of lung cancer in a mouse model

Hiromitsu Takizawa, Kazuya Kondo, Hiroaki Toba, Koichiro Kenzaki, Shoji Sakiyama, Akira Tangoku
Pages: 17-21
Published online on: 01 July 2009

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Article Open Access

Anti-tumor effect of cimetidine via inhibiting angiogenesis factors in N-butyl-N-(4-hydroxybutyl) nitrosamine-induced mouse and rat bladder carcinogenesis

Yoshitomo Chihara, Kiyohide Fujimoto, Makito Miyake, Yoshio Hiasa, Yoshihiko Hirao
Pages: 23-28
Published online on: 01 July 2009

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Article

It is possible that tumour-infiltrating granulocytes promote tumour progression

Huanran Liu, Hideyuki Ubukata, Takanobu Tabuchi, Akira Takemura, Gyou Motohashi, Motoi Nishimura, Tetsuro Satani, Jianwei Hong, Motonobu Katano, Ichiro Nakada, Abbi R. Saniabadi, Takafumi Tabuchi
Pages: 29-33
Published online on: 01 July 2009

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Article

p12CDK2-AP1 is associated with tumor progression and a poor prognosis in esophageal squamous cell carcinoma

Yukiharu Hiyoshi, Masayuki Watanabe, Koutaro Hirashima, Ryuichi Karashima, Nobutaka Sato, Yu Imamura, Youhei Nagai, Naoya Yoshida, Eiichiro Toyama, Naoko Hayashi, Hideo Baba
Pages: 35-39
Published online on: 01 July 2009

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Article

Enhanced S100A4 protein expression is clinicopathologically significant to metastatic potential and p53 dysfunction in colorectal cancer

Joo Heon Kim, Chang Nam Kim, Soo Young Kim, Jung Sam Lee, Daeho Cho, Jae Wha Kim, Sun Young Yoon
Pages: 41-47
Published online on: 01 July 2009

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Article

AFPep, a novel drug for the prevention and treatment of breast cancer, does not disrupt the estrous cycle or fertility in rats

Amanda M. Tower, Andrea Trinward, Katie Lee, Leroy Joseph, Herbert I. Jacobson, James A. Bennett, Thomas T. Andersen
Pages: 49-56
Published online on: 01 July 2009

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Article

Expression and localization of FOXO1 in non-small cell lung cancer

Takayo Maekawa, Yoshimasa Maniwa, Takefumi Doi, Wataru Nishio, Masahiro Yoshimura, Chiho Ohbayashi, Yoshitake Hayashi, Yutaka Okita
Pages: 57-64
Published online on: 01 July 2009

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Article

Establishment and biological analysis of the EC109/CDDP multidrug-resistant esophageal squamous cell carcinoma cell line

Jing Wen, Bin Zheng, Yi Hu, Xu Zhang, Hong Yang, Kong-Jia Luo, Xing Zhang, Yong-Feng Li, Jian-Hua Fu
Pages: 65-71
Published online on: 01 July 2009

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Article

The overexpression of multidrug resistance-associated proteins and gankyrin contribute to arsenic trioxide resistance in liver and gastric cancer cells

Xi Chen, Mu Zhang, Lian-Xin Liu
Pages: 73-80
Published online on: 01 July 2009

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Article

High incidence of chromosomal abnormalities at 1p36 and 9p21 in early-stage central type squamous cell carcinoma and squamous dysplasia of bronchus detected by autofluorescence bronchoscopy

Kiyoko Shibukawa, Naoyuki Miyokawa, Yoshihiko Tokusashi, Takaaki Sasaki, Shinobu Osanai, Yoshinobu Ohsaki
Pages: 81-87
Published online on: 01 July 2009

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Article

Overexpression of mitogen-activated protein kinase kinase 4 and nuclear factor-κB in laryngeal squamous cell carcinoma: A potential indicator for poor prognosis

Chuang Huang, Kun Huang, Chi Wang, Zhen-Dong Jiang, Xing-Xing Li, Hong-Peng Wang, Hong-Yan Chen
Pages: 89-95
Published online on: 01 July 2009

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Article

Curcumin induces apoptosis through FAS and FADD, in caspase-3-dependent and -independent pathways in the N18 mouse-rat hybrid retina ganglion cells

Hsu-Feng Lu, Kuang-Chi Lai, Shu-Chun Hsu, Hui-Ju Lin, Mei-Due Yang, Yuan-Liang Chen, Ming-Jen Fan, Jai-Sing Yang, Pi-Yun Cheng, Chao-Lin Kuo, Jing-Gung Chung
Pages: 97-104
Published online on: 01 July 2009

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Article Open Access

Antiangiogenic versus cytotoxic therapeutic approaches in a mouse model of pancreatic cancer: An experimental study with a multitarget tyrosine kinase inhibitor (sunitinib), gemcitabine and radiotherapy

Veerle F. Casneuf, Pieter Demetter, Tom Boterberg, Louke Delrue, Marc Peeters, Nancy Van Damme
Pages: 105-113
Published online on: 01 July 2009

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Article

Dual functional molecular imaging probe targeting CD20 with PET and optical imaging

Pramila Paudyal, Bishnuhari Paudyal, Yasuhiko Iida, Noboru Oriuchi, Hirofumi Hanaoka, Hideyuki Tominaga, Tomohiro Ishikita, Hiroki Yoshioka, Tetsuya Higuchi, Keigo Endo
Pages: 115-119
Published online on: 01 July 2009

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Article

Inhibition of cell proliferation, migration and invasion by DNAzyme targeting MMP-9 in A549 cells

Lifang Yang, Weizhong Zeng, Dan Li, Rui Zhou
Pages: 121-126
Published online on: 01 July 2009

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Article

Comprehensive analysis of excision repair complementation group 1, glutathione S-transferase, thymidylate synthase and uridine diphosphate glucuronosyl transferase 1A1 polymorphisms predictive for treatment outcome in patients with advanced gastric cancer treated with FOLFOX or FOLFIRI

Bong-Gun Seo, Hyuk-Chan Kwon, Sung Yong Oh, Suee Lee, Sung-Gun Kim, Sung-Hyun Kim, Hoon Han, Hyo-Jin Kim
Pages: 127-136
Published online on: 01 July 2009

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Article

Impact of chromosome 13 deletion and plasma cell load on long-term survival of patients with multiple myeloma undergoing autologous transplantation

Esbjörn Paul, Tolga Sutlu, Stefan Deneberg, Evren Alici, Bo Björkstrand, Monika Jansson, Richard Lerner, Ann Wallblom, Gösta Gahrton, Hareth Nahi
Pages: 137-142
Published online on: 01 July 2009

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Article

Trichostatin A with adenovirus-mediated p53 gene transfer synergistically induces apoptosis in breast cancer cell line MDA-MB-231

Sei-Ichiro Nakajima, Hiroto Niizeki, Mitsuo Tada, Koji Nakagawa, Satoshi Kondo, Futoshi Okada, Masanobu Kobayashi
Pages: 143-148
Published online on: 01 July 2009

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Article

Detection of glypican-3-specific CTLs in chronic hepatitis and liver cirrhosis

Emiko Hayashi, Yutaka Motomura, Hirofumi Shirakawa, Toshiaki Yoshikawa, Nobuyuki Oba, Shuta Nishinakagawa, Yasuhiro Mizuguchi, Tatsuya Kojima, Kazuhiro Nomura, Tetsuya Nakatsura
Pages: 149-154
Published online on: 01 July 2009

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Article

Susceptibility of the human LNCaP prostate cancer cells to the apoptotic effect of marina crystal minerals (MCM) in vitro

Mamdooh Ghoneum, Sastry Gollapudi
Pages: 155-159
Published online on: 01 July 2009

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Article

β-Elemene, a novel plant-derived antineoplastic agent, increases cisplatin chemosensitivity of lung tumor cells by triggering apoptosis

Qingdi Q. Li, Gangduo Wang, Manchao Zhang, Christopher F. Cuff, Lan Huang, Eddie Reed
Pages: 161-170
Published online on: 01 July 2009

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Article

Does dexamethasone inhibit anticancer activity of cetuximab in squamous cell carcinoma cell lines of the head and neck?

Jens Wagenblast, Mehran Baghi, Susanne Mörtel, Daniel Hirth, Laura Thron, Christoph Arnoldner, Wolfgang Gstöttner, Angelika May, Markus Hambek
Pages: 171-176
Published online on: 01 July 2009

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Article

Expression of Jun and Fos proteins in ovarian tumors of different malignant potential and in ovarian cancer cell lines

Sibyll Hein, Sven Mahner, Christine Kanowski, Thomas Löning, Fritz Jänicke, Karin Milde-Langosch
Pages: 177-183
Published online on: 01 July 2009

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Article

Characterization of cytomegalovirus pp65-HLA-A24 peptide-specific CTL lines from metastatic melanoma patients

Yasuto Akiyama, Sachiko Tai, Masaru Komiyama, Masako Takikawa, Chie Ohshita, Akifumi Yamamoto, Naoya Yamazaki, Yoshio Kiyohara
Pages: 185-191
Published online on: 01 July 2009

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Article

Apogossypolone inhibits cell growth by inducing cell cycle arrest in U937 cells

Jian Sun, Zhi-Ming Li, Zhe-Yu Hu, Zhao-Lei Zeng, Da-Jun Yang, Wen-Qi Jiang
Pages: 193-198
Published online on: 01 July 2009

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Article

Correlation of promoter hypermethylation in hTERT, DAPK and MGMT genes with cervical oncogenesis progression

Dimitrios Iliopoulos, Pagona Oikonomou, Ioannis Messinis, Aspasia Tsezou
Pages: 199-204
Published online on: 01 July 2009

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Article

Serum protein profiling for diagnosis of breast cancer using SELDI-TOF MS

Marie-Christine W. Gast, Carla H. Van Gils, Lodewijk F.A. Wessels, Nathan Harris, Johannes M.G. Bonfrer, Emiel J.TH. Rutgers, Jan H.M. Schellens, Jos H. Beijnen
Pages: 205-213
Published online on: 01 July 2009

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Article

The effect of MG132, a proteasome inhibitor on HeLa cells in relation to cell growth, reactive oxygen species and GSH

Yong Hwan Han, Hwa Jin Moon, Bo Ra You, Woo Hyun Park
Pages: 215-221
Published online on: 01 July 2009

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

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[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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