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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2025 Volume 32 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mechanisms and interventions in aneurysmal subarachnoid hemorrhage: Unraveling the role of inflammatory responses and cell death in early brain injury (Review)

Rijin Lin, Sheng Guan, Jian Wang, Mingyang Han, Mengyan Fan, Jiaxin Wan, Xiaowen Zhang, Nan Zhang, Jing Li
Article Number: 256
Published online on: 14 July 2025

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Roles of human SPATA3 in cell proliferation and expression pattern of Spata3 in mouse testis

Li Fu, Baixu Zhou, Xia Jiang, Jingliang Cheng, Qiang Wu, Junjiang Fu
Article Number: 255
Published online on: 10 July 2025

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MicroRNAs: Novel clinical biomarkers for cancer radiotherapy (Review)

Junseok Park, Mi Eun Kim, Jun Sik Lee
Article Number: 254
Published online on: 10 July 2025

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GPM6B inhibits tumor progression by targeting HPGD in lung adenocarcinoma

Yonghuai Li, Xufeng Yao, Qian Chai, Xueyi Feng, Yuhao Ma, Guomeng Li, Hongbin Zhu, Lei Zhao, Qian Dai
Article Number: 253
Published online on: 09 July 2025

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Emerging role of circular RNAs in gastric cancer: From basic biology to clinical applications (Review)

Linkun Wang, Peng Zhou, Huiheng Qu, Zhihui Yang, Yuyang Li, Nan Wang, Jiazeng Xia
Article Number: 252
Published online on: 08 July 2025

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Dexmedetomidine mitigates oxidative stress in H9C2 cardiac myoblasts under a high‑glucose environment via the PI3K/AKT signaling pathway

Yan Qu, Wei Xiong, Rui Zhou, Ning Song, Jinqiao Qian
Article Number: 251
Published online on: 08 July 2025

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Blocking the IL‑6 pathway to treat immune checkpoint inhibitor‑induced inflammatory arthritis (Review)

Liwen Zhao, Chuting Feng, Yong-Jing Gao, Tianzhen He
Article Number: 250
Published online on: 08 July 2025

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Identification and validation of epithelial‑mesenchymal transition‑related genes for diabetic nephropathy by WGCNA and machine learning

Huidi Tang, Kang Li, Xiaojie Wang
Article Number: 249
Published online on: 08 July 2025

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AZD1080, a specific inhibitor of GSK‑3β, inhibits stemness and malignancies in osteosarcoma cancer stem‑like cells

Peiyu Guo, Zhenkai Lou, Hongda Gong, Xiaodong Hou, Chunqiang Zhang, Bing Wang, Kaili Du
Article Number: 248
Published online on: 08 July 2025

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Antifungal resistance: Emerging mechanisms and implications (Review)

Ika N. Kadariswantiningsih, Maulana A. Empitu, Timotius Imanuel Santosa, Yikelamu Alimu
Article Number: 247
Published online on: 08 July 2025

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miR‑145 and miR‑23b co‑transfection decreases proliferation, migration, invasion and protein levels of c‑MYC, ZEB1 and ABCB1 in epithelial ovarian cancer cell lines

Allison Fredes‑Garrido, Álvaro Armijo Cruz, Gloria M. Calaf, Maritza P. Garrido, Carmen Romero
Article Number: 246
Published online on: 08 July 2025

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Retraction Open Access

[Retracted] PADI4‑mediated epithelial‑mesenchymal transition in lung cancer cells

Meiyan Liu, Yang Qu, Xue Teng, Ying Xing, Dandan Li, Chunhong Li, Li Cai
Article Number: 245
Published online on: 07 July 2025

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Centrosome‑, mitotic spindle‑ and cytokinetic bridge‑specific compartmentalization of AGO2 protein in human liver cells undergoing mitosis: Non‑canonical, RNAi‑dependent, control of local homeostasis

Eleni I. Theotoki, Panos Kakoulidis, Konstantinos-Stylianos Nikolakopoulos, Eleni N. Vlachou, Ourania E. Tsitsilonis, Gerassimos E. Voutsinas, Ema Anastasiadou, Dimitrios J. Stravopodis
Article Number: 244
Published online on: 07 July 2025

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Chimeric PD‑1 receptor redirects primary T cells against childhood solid tumors but not to PD‑1 ligand‑positive CD80‑coexpressing cells

Chansu Shin, Masaru Imamura, Yasushi Kasahara, Yuko Suzuki, Minori Baba, Nobuhiro Kubo, Ryosuke Hosokai, Haruko Iwabuchi, Yudai Murayama, Hiroyuki Kawashima, Akira Ogose, Keichiro Mihara, Akihiko Saitoh, Chihaya Imai
Article Number: 243
Published online on: 07 July 2025

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Direct effects of the small molecule PD‑L1 inhibitor BMS‑202 on A375 melanoma cells: Anti‑tumor activity accompanied by increased mitochondrial function

Nieng Zhang, Fenglan Feng, Ruonan Dang, Xiaoqing Zhao, Xingrong Wang, Yuqi  Yang, Jinjin Deng, Yujie Wang, Zhuofan  Wen, Wei  Meng, Xinglan Huang, Shunying  Zhang, Yuqiong Deng, Caifeng  Huang, Peng Yan, Zhongrong Liu, Xiping Cheng
Article Number: 242
Published online on: 07 July 2025

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Review Open Access

Progress in targeting the NLRP3 signaling pathway for inflammatory bowel disease (Review)

Yubo Gong, Zhenqi Han, Siyi Wang, Xuefeng Li, Xinhua Chen, Bo Yang
Article Number: 241
Published online on: 03 July 2025

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Correction Open Access

[Corrigendum] lncRNA TPTEP1 inhibits stemness and radioresistance of glioma through miR‑106a‑5p‑mediated P38 MAPK signaling

Ting Tang, Ling-Xing Wang, Mei-Li Yang, Rong-Mou Zhang
Article Number: 240
Published online on: 01 July 2025

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Combination of machine learning and protein‑protein interaction network established one ATM‑DPP4‑TXN ferroptotic diagnostic model with experimental validation

Mengze Wu, Zhao Zou, Yuce Peng, Suxin Luo
Article Number: 239
Published online on: 02 July 2025

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Retraction Open Access

[Retracted] SIRT1 activation by resveratrol reduces brain edema and neuronal apoptosis in an experimental rat subarachnoid hemorrhage model

Cong Qian, Jianxiang Jin, Jingyin Chen, Jianru Li, Xiaobo Yu, Hangbo Mo, Gao Chen
Article Number: 238
Published online on: 30 June 2025

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DDX3X/MAVS alleviates doxorubicin‑induced cardiotoxicity by regulating stress granules

Kaixiang Zhao, Shaochen Wang, Dandan Feng, Dongwei Wang, Guang Yang, Fangfang Lang
Article Number: 237
Published online on: 24 June 2025

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Retraction Open Access

[Retracted] Placenta‑derived mesenchymal stem cells improve airway hyperresponsiveness and inflammation in asthmatic rats by modulating the Th17/Treg balance

Yingying Li, Hongbo Li, Yinyin Cao, Fuling Wu, Wenbin Ma, Yuesi Wang, Shuzhen Sun
Article Number: 236
Published online on: 23 June 2025

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SLC7A1, SGK1 and HMGB2 are overexpressed in cervical cancer tissues and the miR‑23b‑3p/HMGB2 axis regulates cell migration and invasion

Gladys Wendy Valente‑Niño, Hilda Jiménez‑Wences, Manuel Joaquín Romero‑López, Judit Alarcón‑Millán, Miguel Ángel Mendoza‑Catalán, Oscar Peralta‑Zaragoza, Daniel Hernández‑Sotelo, Carlos Pérez‑Plasencia, Gloria Fernández‑Tilapa
Article Number: 235
Published online on: 20 June 2025

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Polygonatum sibiricum polysaccharide alleviates liver fibrosis through the TGF‑β/Smad signaling pathway and reduces collagen

Yin Yuan, Xiaojing Liu, Tian Zhou, Zhongguang Zhou, Minghai Gong, Yihang Li
Article Number: 234
Published online on: 17 June 2025

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Protective effects of lipid mediators, obtained from docosahexaenoic acid via soybean lipoxygenase, on lipopolysaccharide‑induced acute lung injury through the NF‑κB and Nrf2/HO‑1 signaling pathways

Yan Su, Hack Sun Choi, Soon Kyu Kwon, Yunjon Han, Soon-Chang Cho, Jin Hyuk Shin, Yong-Suk Jang, Jong Hyun Choi, Jeong-Woo Seo
Article Number: 233
Published online on: 17 June 2025

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circRNA hsa_circ_0072107 aggravates myocardial hypertrophy via its function as a competitive endogenous RNA of miR‑516b‑5p

Rui Wang, Yongli He, Wuxia Ma, Jindong Xu, Qi Zhong, Cheng Huang
Article Number: 232
Published online on: 17 June 2025

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Recombinant chromosome 6 open reading frame 120 protein promotes angiogenesis and endothelial‑to‑mesenchymal transition in human umbilical vein endothelial cells via the PI3K/Akt signaling pathway

Yingying Lin, Xin Wang, Yanyan Li, Xinyu Cui, Na Zhu, Xin Li
Article Number: 231
Published online on: 17 June 2025

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Retraction Open Access

[Retracted] Isorhamnetin inhibits IL‑1β‑induced expression of inflammatory mediators in human chondrocytes

Jin Li, Ruishan Wu, Xiaoping Qin, Dongyang Liu, Fenjie Lin, Qinglu Feng
Article Number: 230
Published online on: 17 June 2025

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Journal Cover
September-2026 Volume 34 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Chronic kidney disease‑associated encephalopathy: Clinical features, pathomechanisms and emerging therapeutic strategies (Review)

Nanling Zeng, Ling Jiang, Yang Zhang, Jian Liu, Qiong Zhang, Lishang Liao, Qiongdan Hu
Article Number: 259
Published online on: 21 July 2026

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Retraction Open Access

[Retracted] Emodin promotes the arrest of human lymphoma Raji cell proliferation through the UHRF1‑DNMT3A‑∆Np73 pathways

Yun Lin, Weiming Chen, Zhihong Wang, Pengwei Cai
Article Number: 258
Published online on: 20 July 2026

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Sedanolide alleviates LPS‑induced depressive‑like behaviors by modulating the C3a/C3aR signaling axis and microglial glycolysis

Shaocong Lu, Fangla Luo, Niqi Chen, Gongde Shi, Yeru Chen
Article Number: 257
Published online on: 16 July 2026

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Expression of Concern Open Access

[Expression of Concern] Chrysophanol inhibits proliferation and induces apoptosis through NF‑κB/cyclin D1 and NF‑κB/Bcl‑2 signaling cascade in breast cancer cell lines

Li Ren, Zhouping Li, Chunmei Dai, Danyu Zhao, Yanjie Wang, Chunyu Ma, Chun Liu
Article Number: 256
Published online on: 15 July 2026

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Article Open Access

PCSK9 alleviates doxorubicin‑induced pyroptosis of cardiomyocytes

Chaochu Cui, Jinyu Zhao, Xiaoqian Li, Shengming Huang, Gang Liu, Xinhui Xu, Can Guo, Tiesuo Zhao, Jiang Du, Shipeng Li, Xianwei Wang, Jianbo Yang
Article Number: 255
Published online on: 14 July 2026

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Review Open Access

From cell to disease: Regulatory networks and mechanisms of super‑enhancers in aging (Review)

Xiaodan Wang, Weiqian Deng, Shuangxi Tu, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 254
Published online on: 14 July 2026

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Retraction Open Access

[Retracted] Matrine‑induced apoptosis in Hep3B cells via the inhibition of MDM2

Ning Zhou, Jiequn Li, Ting Li, Guangshun Chen, Zhongqiang Zhang, Zhongzhou Si
Article Number: 253
Published online on: 13 July 2026

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Review Open Access

Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review)

Lan Wang, Zhiyuan Ma, Bei Ji, Shuhui Liu, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 252
Published online on: 09 July 2026

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Article

Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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Correction Open Access

[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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Review Open Access

A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
Published online on: 07 July 2026

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Review Open Access

Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Article Open Access

Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Review Open Access

Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Review Open Access

Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Article Open Access

Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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Review Open Access

TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Article Open Access

Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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Retraction Open Access

[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Article Open Access

Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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Journal Cover
October-2026 Volume 34 Issue 4

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Histone deacetylase 3‑mediated histone deacetylation combined with activating transcription factor 3 promotes renal fibrosis by inhibiting Klotho

Zhiying Yang, Xueling Wang, Wenhong Li, Hao Chen, Gang Liu
Article Number: 274
Published online on: 06 August 2026

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Mitochondrial quality control in acute liver injury and its therapeutic implications (Review)

Ziqiang Chen, Yunhe Wang, Yijing Li, Gang Cong, Yunhang Chu, Yunhui Bai, Yishuo Zhang, Liya Zhou
Article Number: 273
Published online on: 05 August 2026

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STC1 promotes osteogenic differentiation and represses inflammation via inhibition of NF‑κB signaling in mesenchymal stromal cells

Chen Yang, Xin Li, Peng Wang, Yitong Chen, Erli Wu, Qian Chen, Jing Hu, Fu Zheng, Lamu Gongsang, Jiayu Li, Mengyuan Zhang, Jing Zhou, Bing Han, Amr A. Badreldin, Yuka Miyamoto, Jin Koo Kim, Insoon Chang, Jia Chang, Paul H. Krebsbach, Liyuan Huang, Xiaoping Xu, Xiaoyan Chen, Peng Deng, Qianming Chen, Lijie Fan
Article Number: 272
Published online on: 05 August 2026

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Research progress on the protective effect and oxidative stress mechanism of rutin against liver injury (Review)

Teng Sun, Lei Ye
Article Number: 271
Published online on: 04 August 2026

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Role of microbial metabolites in the pathogenesis of hypertensive disorders of pregnancy: From short‑chain fatty acids to tryptophan metabolites (Review)

Fengyun Gao, Lili Wang, Guiyun Teng, Liqiong Shang
Article Number: 270
Published online on: 03 August 2026

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[Retracted] Tumor promoter role of miR‑647 in gastric cancer via repression of TP73

Xiangqian Zhang, Min Zhang, Guifeng Wang, Ye Tian, Xiaolong He
Article Number: 269
Published online on: 03 August 2026

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Gut microbiota‑immune crosstalk in recurrent pregnancy loss: Mechanisms and therapeutic perspectives (Review)

Nanjian Luo, Han Hu, Xiaoting Zeng, Yi Huan Zhang, Qi Deng, En Ni Tang, Yu Hu
Article Number: 268
Published online on: 31 July 2026

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Integrating gut‑brain axis insights into bundled nutrition care for critically ill patients: From mechanisms to implementation (Review)

Liqi Zhang, Shuxia Yang, Huiyan Wu, Hong Zhou
Article Number: 267
Published online on: 30 July 2026

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Role of CMTM6 in disease pathogenesis and clinical translation potential (Review)

Rongtou Huang, Danning Mo, Huitian Huang, Minmin Zhang, Wenhong Yu, Buqing Cao
Article Number: 266
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Identification of key differentially expressed genes associated with non‑small cell lung cancer by bioinformatics analyses

Yubo Xiao, Min Feng, Haiying Ran, Xiao Han, Xuegang Li
Article Number: 265
Published online on: 29 July 2026

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Advances in miR‑200c regulation of apoptosis, pyroptosis and autophagy in disease (Review)

Xiaona Wang, Hua Du, Yingxu Shi
Article Number: 264
Published online on: 28 July 2026

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Review Open Access

Association between periodontitis and heart failure: Mechanisms and clinical implications (Review)

Xinyue Zhang, Xiaoli An
Article Number: 263
Published online on: 28 July 2026

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Article Open Access

Ginsenosides alleviate the progression of hepatic fibrosis by targeting the liver circadian clock gene CLOCK

Jiawen Yu, Chunmei Qian, Renye Que, Yi Zhou
Article Number: 262
Published online on: 28 July 2026

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Retraction Open Access

[Retracted] PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin, Yuezhong Shen, Jingyang Su
Article Number: 261
Published online on: 27 July 2026

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Article Open Access

UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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