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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July 2007 Volume 18 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Potential for molecular-targeted therapy targeting human epidermal growth factor receptor-2 for invasive bladder cancer

Yoshiaki Yamada, Katsuya Naruse, Kogenta Nakamura, Shigeyuki Aoki, Tomohiro Taki, Motoi Tobiume, Kenji Zennami, Remi Katsuda, Yasusuke Inoue, Hiroshi Noguchi, Nobuaki Honda
Pages: 3-7
Published online on: 01 July 2007

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Article

Epithelioid gastric stromal tumours of the antrum in young females with the Carney triad: A report of three new cases with mutational analysis and comparative genomic hybridization

Abbas Agaimy, Antje-Friederike Pelz, Christopher L. Corless, Peter H. Wünsch, Michael C. Heinrich, Ferdinand Hofstaedter, Wolfgang Dietmaier, Charles D. Blanke, Peter Wieacker, Albert Roessner, Arndt Hartmann, Regine Schneider-Stock
Pages: 9-15
Published online on: 01 July 2007

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Article

Detection of activated K-ras in non-small cell lung cancer by membrane array: A comparison with direct sequencing

Inn-Wen Chong, Mei-Yin Chang, Chau-Chyun Sheu, Cheng-Yuan Wang, Jhi-Jhu Hwang, Ming-Shyan Huang, Shiu-Ru Lin
Pages: 17-24
Published online on: 01 July 2007

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Article

Analysis of the expression of estrogen receptor, progesterone receptor and chicken ovalbumin upstream promoter-transcription factor I in ovarian epithelial cancers and normal ovaries

Robério De Sousa Damião, Celina Tizuko Fujiyama Oshima, João Norberto Stávale, Wagner José Gonçalves
Pages: 25-32
Published online on: 01 July 2007

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Article

Sensitivity to CPT-11 and platinum derivatives of stage I/II node-negative breast, lung, and gastric cancer with occult neoplastic cells in lymph node sinuses

Masaya Mukai, Shinkichi Sato, Hiromi Ninomiya, Kanako Wakui, Nobukazu Komatsu, Naruaki Matsui, Masato Nakamura, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 33-39
Published online on: 01 July 2007

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Article

Expression of Epstein-Barr virus in renal cell carcinoma

Misuzu Shimakage, Kunimitsu Kawahara, Shizuko Harada, Toshiyuki Sasagawa, Toshiaki Shinka, Toshitsugu Oka
Pages: 41-46
Published online on: 01 July 2007

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Article

Anti-tumor effects of bevacizumab in combination with paclitaxel on head and neck squamous cell carcinoma

Kyoko Fujita, Daisuke Sano, Machiko Kimura, Yukiko Yamashita, Mariko Kawakami, Yukari Ishiguro, Goshi Nishimura, Hideki Matsuda, Mamoru Tsukuda
Pages: 47-51
Published online on: 01 July 2007

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Article

CYP2A6 overexpression in human lung cancers correlates with a high malignant status

Yoko Matsuda, Keiko Yamakawa, Kousuke Saoo, Kyoko Hosokawa, Masanao Yokohira, Toshiya Kuno, Junko Iwai, Takatoshi Shirai, Kaoru Obika, Tetsuya Kamataki, Katsumi Imaida
Pages: 53-57
Published online on: 01 July 2007

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Article

Expression of orotate phosphoribosyl transferase in human pancreatic cancer: Implication for the efficacy of uracil and tegafur-based adjuvant chemotherapy

Yoshinori Nio, Tomoko Toga, Riruke Maruyama, Masakazu Fukushima
Pages: 59-64
Published online on: 01 July 2007

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Article

X-linked inhibitor of apoptosis (XIAP) and XIAP-associated factor-1 expressions and their relationship to apoptosis in human hepatocellular carcinoma and non-cancerous liver tissues

Ryosuke Sakemi, Hirohisa Yano, Sachiko Ogasawara, Jun Akiba, Osamu Nakashima, Suguru Fukahori, Michio Sata, Masamichi Kojiro
Pages: 65-70
Published online on: 01 July 2007

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Article

Reactive oxygen species regulate Bax translocation and mitochondrial transmembrane potential, a possible mechanism for enhanced TRAIL-induced apoptosis by CCCP

Atul A. Chaudhari, Jae-Won Seol, Shang-Jin Kim, You-Jin Lee, Hyung-sub Kang, In-shik Kim, Nam-Soo Kim, Sang-Youel Park
Pages: 71-76
Published online on: 01 July 2007

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Article

γ-Secretase inhibitors suppress the growth of leukemia and lymphoma cells

Hanae Kogoshi, Taku Sato, Takatoshi Koyama, Nobuo Nara, Shuji Tohda
Pages: 77-80
Published online on: 01 July 2007

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Article

Prognostic significance of expression of nm23-H1 and focal adhesion kinase in non-small cell lung cancer

Nan-Yung Hsu, Chih-Yi Chen, Chung-Ping Hsu, Tze-Yi Lin, Ming-Chih Chou, Shiow-Her Chiou, Kuan-Chih Chow
Pages: 81-85
Published online on: 01 July 2007

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Article

CDX2 as a useful marker of colorectal adenocarcinoma metastases to lung in pre-operative biopsy specimens

Shigebumi Tanaka, Kana Saito, Tomokazu Ito, Kohei Tajima, Akira Mogi, Yoshinori Shitara, Takaaki Sano, Hiroyuki Kuwano
Pages: 87-92
Published online on: 01 July 2007

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Article

Elevated N-myristoyltransferase activity and expression in oral squamous cell carcinoma

Anuraag Shrivastav, Anil R. Sharma, Gagan Bajaj, Chandrashekhar Charavaryamath, Wendelin Ezzat, Peter Spafford, Rick Gore-Hickman, Baljit Singh, Maria A. Copete, Rajendra K. Sharma
Pages: 93-97
Published online on: 01 July 2007

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Article

Overexpression of cysteinyl LT1 receptor in prostate cancer and CysLT1R antagonist inhibits prostate cancer cell growth through apoptosis

Masahide Matsuyama, Takuma Hayama, Kiyoaki Funao, Yutaka Kawahito, Hajime Sano, Yoshiaki Takemoto, Tatsuya Nakatani, Rikio Yoshimura
Pages: 99-104
Published online on: 01 July 2007

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Article

RARβ2 suppression in head and neck squamous cell carcinoma correlates with site, histology and age

Judit Olasz, Alíz Juhász, Éva Remenár, Helga Engi, Mihály Bak, Orsolya Csuka, Miklós Kásler
Pages: 105-112
Published online on: 01 July 2007

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Article

The effect of chemotherapy on Ki-67, Bcl-2 and Bak expression in primary tumors and lymph node metastases of breast cancer

Mariusz Koda, Mariola Sulkowska, Luiza Kanczuga-Koda, Jakub Tomaszewski, Waldemar Kucharczuk, Tomasz Lesniewicz, Slawomir Cymek, Stanislaw Sulkowski
Pages: 113-119
Published online on: 01 July 2007

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Article

C-erbB-2 expression is a better predictor for survival than galectin-3 or p53 in early-stage breast cancer

Angela F. Logullo, Andreia B.G. Lopes, Suely Nonogaki, Fernando A. Soares, Mario Mourão Netto, Inês N. Nishimoto, M. Mitzi Brentani
Pages: 121-126
Published online on: 01 July 2007

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Article

Differential methylation of the OCT3/4 upstream region in primary human testicular germ cell tumors

Jeroen De Jong, Sannah Weeda, Ad J.M. Gillis, J. Wolter Oosterhuis, Leendert H.J. Looijenga
Pages: 127-132
Published online on: 01 July 2007

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Article

The role of the endothelin axis and microvessel density in bladder cancer - correlation with tumor angiogenesis and clinical prognosis

Edwin Herrmann, Martin Bögemann, Stefan Bierer, Elke Eltze, Marieta I. Toma, Thomas Köpke, Lothar Hertle, Christian Wülfing
Pages: 133-138
Published online on: 01 July 2007

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Article

Activated Akt signaling pathway in invasive ductal carcinoma of the breast: Correlation with HER2 overexpression

Sung-Shin Park, Sung-Won Kim
Pages: 139-143
Published online on: 01 July 2007

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Article

Plasma levels and expression of vascular endothelial growth factor-A in human localized prostate cancer

Michaël Peyromaure, Cécile Badoual, Philippe Camparo, Sophie Grabar, Claire Goulvestre, Yvonne Fulla, Annick Vieillefond, Kaili Mao, Anh-Tuan Dinh-Xuan
Pages: 145-149
Published online on: 01 July 2007

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Article

Coexpression of EGFR and HER-2 in pancreatic ductal adenocarcinoma: A comparative study using immunohistochemistry correlated with gene amplification by fluorescencent in situ hybridization

Jane Dancer, Hidehiro Takei, Jae Y. Ro, Mary Lowery-Nordberg
Pages: 151-155
Published online on: 01 July 2007

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Article

A comparison of liquid-based cytology and Pap smear as a screening method for cervical cancer

Jie Zhu, Ingrid Norman, Kristina Elfgren, Vera Gaberi, Bjorn Hagmar, Anders Hjerpe, Sonia Andersson
Pages: 157-160
Published online on: 01 July 2007

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Article

Increased levels of IgG antibodies against peptides of the prostate stem cell antigen in the plasma of pancreatic cancer patients

Masahiro Tanaka, Nobukazu Komatsu, Naoyoshi Terakawa, Yasuaki Yanagimoto, Masao Oka, Tetsuro Sasada, Takashi Mine, Shojiro Gouhara, Shigeki Shichijo, Seiya Okuda, Kyogo Itoh
Pages: 161-166
Published online on: 01 July 2007

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Article

Anti-progestins suppress the growth of established tumors induced by 7,12-dimethylbenz(a)anthracene: Comparison between RU486 and a new 21-substituted-19-nor-progestin

Ronald D. Wiehle, Konstantin Christov, Rajendra Mehta
Pages: 167-174
Published online on: 01 July 2007

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Article

E-cadherin increases squamous cell carcinoma antigen expression through phosphatidylinositol-3 kinase-Akt pathway in squamous cell carcinoma cell lines

Tatsushi Nakagawa, Akihiro Murakami, Mayumi Torii, Shugo Nawata, Osamu Takeda, Norihiro Sugino
Pages: 175-179
Published online on: 01 July 2007

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Article

Induction of apoptosis by isothiocyanate sulforaphane in human cervical carcinoma HeLa and hepatocarcinoma HepG2 cells through activation of caspase-3

Soung Young Park, Gi Young Kim, Song-Ja Bae, Young Hyun Yoo, Yung Hyun Choi
Pages: 181-187
Published online on: 01 July 2007

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Article

Repeat reduction surgery after an initial hepatectomy for patients with colorectal cancer

Kenji Matsuda, Tsukasa Hotta, Kazuhisa Uchiyama, Masaji Tani, Katsunari Takifuji, Shozo Yokoyama, Takashi Higashiguchi, Toshiji Tominaga, Yoshimasa Oku, Toru Nasu, Hiroki Yamaue
Pages: 189-194
Published online on: 01 July 2007

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Article

Differential regulation of the cytotoxicity activity of paclitaxel by orobol and platelet derived growth factor in human ovarian carcinoma cells

Seiji Isonishi, Motoaki Saitou, Misato Saitou, Makoto Yasuda, Tadao Tanaka
Pages: 195-201
Published online on: 01 July 2007

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Article

Do thymidylate synthase gene promoter polymorphism and the C/G single nucleotide polymorphism predict effectiveness of adjuvant 5-fluorouracil-based chemotherapy in stage III colonic adenocarcinoma?

Friedrich Prall, Christiane Ostwald, Leif Schiffmann, Malte Barten
Pages: 203-209
Published online on: 01 July 2007

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Article

A polymorphism C3435T of the MDR-1 gene associated with smoking or high body mass index increases the risk of sporadic breast cancer in women

Pavol Zubor, Zora Lasabova, Jozef Hatok, Andrea Stanclova, Jan Danko
Pages: 211-217
Published online on: 01 July 2007

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Article

Effect of 41°C and 43°C on cisplatin radiosensitization in two human carcinoma cell lines with different sensitivities for cisplatin

Judith W.J. Bergs, Jaap Haveman, Rosemarie Ten Cate, Jan Paul Medema, Nicolaas A.P. Franken, Chris van Bree
Pages: 219-226
Published online on: 01 July 2007

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Article

Anti-proliferative and antioxidant activities of Saposhnikovia divaricata

Joseph Tai, Susan Cheung
Pages: 227-234
Published online on: 01 July 2007

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Article

Association of polymorphisms in myeloperoxidase and catalase genes with precancerous changes in the gastric mucosa of patients at inner-city hospitals in New York

M. Steenport, H. Eom, M. Uezu, J. Schneller, R. Gupta, Y. Mustafa, R. Villanueva, E. W. Straus, R. D. Raffaniello
Pages: 235-240
Published online on: 01 July 2007

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Article

VEGF-C, VEGFR-3, and COX-2 enhances growth and metastasis of human cervical carcinoma cell lines in vitro

Xiaoyan Shi, Gang Chen, Hui Xing, Danhui Weng, Xiangyang Bai, Ding Ma
Pages: 241-247
Published online on: 01 July 2007

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Article

Expression study of the target receptor tyrosine kinase of Imatinib mesylate in skull base chordomas

Francesca Orzan, Maria Rosa Terreni, Mauro Longoni, Nicola Boari, Pietro Mortini, Claudio Doglioni, Paola Riva
Pages: 249-252
Published online on: 01 July 2007

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Article

Analysis of PIK3CA and Akt/protein kinase B in head and neck squamous cell carcinoma

Irina Fenic, Klaus Steger, Christin Gruber, Christoph Arens, Joachim Woenckhaus
Pages: 253-259
Published online on: 01 July 2007

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Article

Expression of erbB-1 and erbB-2 genes in normal and pathological human endometrium

Magdalena Brys, Andrzej Semczuk, Tomasz Rechberger, Wanda M. Krajewska
Pages: 261-265
Published online on: 01 July 2007

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Article

Abrogation of the p16-retinoblastoma-cyclin D1 pathway in head and neck squamous cell carcinomas

Hun-Woong Park, Si-Youn Song, Tae-Jin Lee, Daewon Jeong, Tae-Yoon Lee
Pages: 267-272
Published online on: 01 July 2007

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Article

GP7 induces internucleosomal DNA fragmentation independent of caspase activation and DNA fragmentation factor in NB4 cells

She-Ning Qi, Yuan-Xue Jing, Gen-Xi Dong, Yan Chen, Akira Yoshida, Takanori Ueda
Pages: 273-277
Published online on: 01 July 2007

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Article

Anti-tumor effects of immunotherapeutic peptide on the treatment of hepatocellular carcinoma with HBc carrier

Jing Kong, Zhenyu Diao, Xiaozhao Deng, Hui Zhong, Wenjuan Yao, Xuefang Hu
Pages: 279-285
Published online on: 01 July 2007

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Article

Mechanisms of action of FdUMP[10]: Metabolite activation and thymidylate synthase inhibition

I. V. Bijnsdorp, E. M. Comijn, J. M. Padron, W. H. Gmeiner, G. J. Peters
Pages: 287-291
Published online on: 01 July 2007

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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