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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2008 Volume 20 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Expression of adiponectin receptors, AdipoR1 and AdipoR2, in normal colon epithelium and colon cancer tissue

Kyoko Yoneda, Ayako Tomimoto, Hiroki Endo, Hiroshi Iida, Michiko Sugiyama, Hirokazu Takahashi, Hironori Mawatari, Yuichi Nozaki, Koji Fujita, Masato Yoneda, Masahiko Inamori, Noriko Nakajima, Koichiro Wada, Yoji Nagashima, Hitoshi Nakagama, Hitoshi Uozaki, Masashi Fukayama, Atsushi Nakajima
Pages: 479-483
Published online on: 01 September 2008

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Article

Sstr2A immunohistochemical expression in human meningiomas: Is there a correlation with the histological grade, proliferation or microvessel density?

V. Barresi, C. Alafaci, F. Salpietro, G. Tuccari
Pages: 485-492
Published online on: 01 September 2008

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Article

Aqueous and ethanolic extract fractions from the Brazilian propolis suppress azoxymethane-induced aberrant crypt foci in rats

Yumiko Yasui, Shingo Miyamoto, Mihye Kim, Hiroyuki Kohno, Shigeyuki Sugie, Takuji Tanaka
Pages: 493-499
Published online on: 01 September 2008

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Article

Characterization and gene expression analysis of novel matched primary and metastatic renal cell carcinoma cell lines

Yoshio Ohno, Miki Izumi, Masaaki Tachibana, Takeshi Kawamura, Kunihiko Yoshioka, Teiichiro Aoyagi, Makoto Ohori, Kazunori Namiki, Noboru Sakamoto, Yoshihiro Nakagami, Tadashi Hatano, Shingo Akimoto, Toshihide Nishimura
Pages: 501-509
Published online on: 01 September 2008

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Article

Prognostic significance of tenascin-C expression in clear cell renal cell carcinoma

Yoshio Ohno, Miki Izumi, Kunihiko Yoshioka, Makoto Ohori, Hiroyuki Yonou, Masaaki Tachibana
Pages: 511-516
Published online on: 01 September 2008

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Article Open Access

Efficacy of the combined use of bevacizumab and irinotecan as a postoperative adjuvant chemotherapy in colon carcinoma

Tomoaki Mizobe, Yutaka Ogata, Hidetsugu Murakami, Yoshito Akagi, Nobuya Ishibashi, Shinjirou Mori, Teruo Sasatomi, Kazuo Shirouzu
Pages: 517-523
Published online on: 01 September 2008

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Article

Prognostic value of the co-expression of carbonic anhydrase IX and vascular endothelial growth factor in patients with clear cell renal cell carcinoma

Nguyen Ba Phuoc, Hidetoshi Ehara, Takahiro Gotoh, Masahiro Nakano, Shingo Kamei, Takashi Deguchi, Yoshinobu Hirose
Pages: 525-530
Published online on: 01 September 2008

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Article

Patterns of recurrence and survival in breast cancer

Daniela Navarrete Montalvo, Nicolás González M, María T. Montalvo V, Andrea Jiménez A, Carlos Echiburú-Chau, Gloria M. Calaf
Pages: 531-535
Published online on: 01 September 2008

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Article

No relationship between 18F-fluorodeoxyglucose positron emission tomography and expression of Glut-1 and -3 and hexokinase I and II in high-grade glioma

N. Charnley, R. Airley, D. Du Plessis, C. West, C. Brock, C. Barnett, J. Matthews, K. Symonds, M. Bottomly, R. Swindell, P. Price
Pages: 537-542
Published online on: 01 September 2008

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Article

GFP image analysis in the mouse orthotopic bladder cancer model

Marco A. De Velasco, Motoyoshi Tanaka, Satoshi Anai, Atsushi Tomioka, Kazuto Nishio, Hirotsugu Uemura
Pages: 543-547
Published online on: 01 September 2008

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Article

Serum amyloid A mediates the inhibitory effect of Ganoderma lucidum polysaccharides on tumor cell adhesion to endothelial cells

Ying-Bo Li, Rui Wang, Hong-Li Wu, Yu-Hua Li, Li-Jun Zhong, He-Ming Yu, Xue-Jun Li
Pages: 549-556
Published online on: 01 September 2008

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Article

Long exposure of non-cytotoxic concentrations of methylselenol suppresses the invasive potential of B16F10 melanoma

Aeyung Kim, Ji-Yong Jung, Minsik Son, Sang-Han Lee, Jong-Seok Lim, An-Sik Chung
Pages: 557-565
Published online on: 01 September 2008

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Article

PJ34, an inhibitor of PARP-1, suppresses cell growth and enhances the suppressive effects of cisplatin in liver cancer cells

Sheng-Hui Huang, Min Xiong, Xiao-Ping Chen, Zhen-Yu Xiao, Yin-Feng Zhao, Zhi-Yong Huang
Pages: 567-572
Published online on: 01 September 2008

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Article

Reduced expression of PDCD5 is associated with high-grade astrocytic gliomas

Haiyan Li, Qun Wang, Fei Gao, Faliang Zhu, Xiaoyan Wang, Chengjun Zhou, Chunmei Liu, Yingyu Chen, Chunhong Ma, Wensheng Sun, Lining Zhang
Pages: 573-579
Published online on: 01 September 2008

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Article

Synergistic inhibitory activity of zoledronate and paclitaxel on bone metastasis in nude mice

Shun Lu, Jie Zhang, Zhen Zhou, Mei-Lin Liao, Wei-Zhong He, Xiao-Yan Zhou, Zi-Ming Li, Jia-Qing Xiang, Jie-Jun Wang, Hai-Quan Chen
Pages: 581-587
Published online on: 01 September 2008

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Article Open Access

Skp2, p27kip1 and EGFR assessment in head and neck squamous cell carcinoma: Prognostic implications

Dario G. Carracedo, Aurora Astudillo, Juan P. Rodrigo, Carlos Suarez, Maria Victoria Gonzalez
Pages: 589-595
Published online on: 01 September 2008

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Article

Significance of p-STAT3 expression in human colorectal adenocarcinoma

Jae-Kyoung Park, Ran Hong, Kyung-Jong Kim, Tae-Bum Lee, Sung-Chul Lim
Pages: 597-604
Published online on: 01 September 2008

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Article

Induction of apoptosis and cell cycle arrest by NS398 in oral squamous cell carcinoma cells via downregulation of E2 promoter-binding factor-1

Yifei Du, Shuangyue Zhang, Zilu Wang, Weina Zhou, Mingliang Luan, Xiaohan Yang, Ning Chen
Pages: 605-611
Published online on: 01 September 2008

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Article

Overexpression of telomerase-associated chaperone proteins in prostatic intraepithelial neoplasia and carcinomas

Lynne W. Elmore, Robert Forsythe, Heidi Forsythe, A. Taylor Bright, Suhail Nasim, Kanendori Endo, Shawn E. Holt
Pages: 613-617
Published online on: 01 September 2008

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Article

Frequent down-regulation of pim-1 mRNA expression in non-small cell lung cancer is associated with lymph node metastases

Ute Warnecke-Eberz, Elfriede Bollschweiler, Uta Drebber, Alexandra Pohl, Stephan E. Baldus, Arnulf H. Hoelscher, Ralf Metzger
Pages: 619-624
Published online on: 01 September 2008

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Article

Linalool, a plant-derived monoterpene alcohol, reverses doxorubicin resistance in human breast adenocarcinoma cells

Raffaella Ravizza, Marzia B. Gariboldi, Roberta Molteni, Elena Monti
Pages: 625-630
Published online on: 01 September 2008

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Article

Integrin αvβ3 is not significantly implicated in the anti-migratory effect of anti-angiogenic urokinase kringle domain

Eunju O, Hyun-Kyung Kim, Sung Hee Hong, Chung Kwon Kim, Yong-Kil Hong, Young Ae Joe
Pages: 631-636
Published online on: 01 September 2008

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Article

Role of p38 MAPK and JNK in enhanced cervical cancer cell killing by the combination of arsenic trioxide and ionizing radiation

Young-Hee Kang, Su-Jae Lee
Pages: 637-643
Published online on: 01 September 2008

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Article

In vitro susceptibility to anticancer agents of the human KB carcinoma cell line transfected with COX-2 cDNA

Kazuki Takaoka, Hiromitsu Kishimoto, Emi Segawa, Nao Otsu, Yusuke Zushi, Susumu Hashitani, Kazuma Noguchi, Masahiro Urade
Pages: 645-649
Published online on: 01 September 2008

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Article

Long-term effects of multimodal treatment for patients with resectable carcinoma of the pancreas

Takehiro Okabayashi, Isao Nishimori, Akihito Nishioka, Koichi Yamashita, Takeki Sugimoto, Ken Dabanaka, Hiromichi Maeda, Takuhiro Kohsaki, Yasuhiro Ogawa, Michiya Kobayashi, Saburo Onishi, Kazuhiro Hanazaki
Pages: 651-656
Published online on: 01 September 2008

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Article

Analysis of caspase activities in rat mammary tumours induced by N-methyl-nitrosourea

M. A. Puertollano, M. P. Carrera, E. Puertollano, G. Álvarez de Cienfuegos, M. J. Ramirez-Expósito, M. A. De Pablo, J. M. Martinez-Martos
Pages: 657-662
Published online on: 01 September 2008

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Article

Oral squamous cell carcinomas stimulate osteoclast differentiation

Yoshiaki Deyama, Kanchu Tei, Yoshitaka Yoshimura, Yuri Izumiyama, Sadaaki Takeyama, Mitsutoki Hatta, Yasunori Totsuka, Kuniaki Suzuki
Pages: 663-668
Published online on: 01 September 2008

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Article

Screening cellular proteins involved in the anti-proliferative effect of the ADAM15 disintegrin domain in murine melanoma cells

Jing Wu, Lianfen Zhang, Xiaofeng Ma, Xiaoping Zhang, Jian Jin
Pages: 669-675
Published online on: 01 September 2008

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Article

Characterization of regulatory T cells in patients with B-cell chronic lymphocytic leukemia

Krzysztof Giannopoulos, Michael Schmitt, Malgorzata Kowal, Paulina Wlasiuk, Agnieszka Bojarska-Junak, Jinfei Chen, Jacek Rolinski, Anna Dmoszynska
Pages: 677-682
Published online on: 01 September 2008

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Article

The prevalence of mtDNA4977 deletion in primary human endometrial carcinomas and matched control samples

Konrad Futyma, Lechoslaw Putowski, Marek Cybulski, Pawel Miotla, Tomasz Rechberger, Andrzej Semczuk
Pages: 683-688
Published online on: 01 September 2008

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Article

Antimycin A as a mitochondrial electron transport inhibitor prevents the growth of human lung cancer A549 cells

Yong Hwan Han, Suhn Hee Kim, Sung Zoo Kim, Woo Hyun Park
Pages: 689-693
Published online on: 01 September 2008

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Impact of the intratumoral resident microbiome on the immune microenvironment of malignant tumors (Review)

Han Na Oh, Hoon Hur
Article Number: 66
Published online on: 06 February 2026

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Correction Open Access

[Corrigendum] Hypoxia and macrophages promote glioblastoma invasion by the CCL4‑CCR5 axis

Ying Wang, Tao Liu, Ning Yang, Shuo Xu, Xingang Li, Donghai Wang
Article Number: 65
Published online on: 04 February 2026

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Review Open Access

Origin dictates function: The dual roles of exosomes derived from diverse origins in the onset and progression of colorectal cancer (Review)

Zhao Guo, Haoyan Zhuang, Qingfeng Liu
Article Number: 64
Published online on: 03 February 2026

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Article Open Access

Quercetin reduces expression of ATP‑binding cassette transporters by regulating the PTEN/PI3K/AKT signaling pathway in breast cancer cells

Wentao Fu, Leying Lin, Jie Li, Fei Qin, Chuan Chen, Yinglian Cai, Yilun Cai, Yiling Huang, Wang Yang, Shanshan Zhu
Article Number: 63
Published online on: 02 February 2026

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Article Open Access

POSTN+ fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling

Chenyang Zhang, Si Chen, Chenghui Qian, Wanqi Lv, Qian Zhang, Yanjin Wang, Yuqiong Wu, Xue Liu
Article Number: 62
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] EGFR/HER2 inhibitors effectively reduce the malignant potential of MDR breast cancer evoked by P‑gp substrates in vitro and in vivo

Yiting Jin, Wei Zhang, Hongying Wang, Zijing Zhang, Chengyu Chu, Xiuping Liu, Qiang Zou
Article Number: 61
Published online on: 02 February 2026

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Article

Tumor‑associated glucocorticoid inhibition by mifepristone reduces polymorphonuclear myeloid‑derived suppressor cells and promotes antitumor immunity in triple‑negative breast cancer‑bearing mice

Masato Kobayashi, Chisana Konno, Ayato Shimizu, Masanori Kobayashi, Tatsuya Hori
Article Number: 60
Published online on: 30 January 2026

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Review Open Access

Mitochondria in T‑cell tumor immunity and tumor therapies targeting mitochondria (Review)

Minjie Zhou, Yijie Xie, Zhipeng Liu, Yi He, Yibing Yin, Keyu Chen, Zhengyu Zhao, Chengshun Zhang, Dingjun Cai
Article Number: 59
Published online on: 29 January 2026

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Article Open Access

TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Review Open Access

Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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