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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2008 Volume 20 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Expression of adiponectin receptors, AdipoR1 and AdipoR2, in normal colon epithelium and colon cancer tissue

Kyoko Yoneda, Ayako Tomimoto, Hiroki Endo, Hiroshi Iida, Michiko Sugiyama, Hirokazu Takahashi, Hironori Mawatari, Yuichi Nozaki, Koji Fujita, Masato Yoneda, Masahiko Inamori, Noriko Nakajima, Koichiro Wada, Yoji Nagashima, Hitoshi Nakagama, Hitoshi Uozaki, Masashi Fukayama, Atsushi Nakajima
Pages: 479-483
Published online on: 01 September 2008

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Article

Sstr2A immunohistochemical expression in human meningiomas: Is there a correlation with the histological grade, proliferation or microvessel density?

V. Barresi, C. Alafaci, F. Salpietro, G. Tuccari
Pages: 485-492
Published online on: 01 September 2008

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Article

Aqueous and ethanolic extract fractions from the Brazilian propolis suppress azoxymethane-induced aberrant crypt foci in rats

Yumiko Yasui, Shingo Miyamoto, Mihye Kim, Hiroyuki Kohno, Shigeyuki Sugie, Takuji Tanaka
Pages: 493-499
Published online on: 01 September 2008

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Article

Characterization and gene expression analysis of novel matched primary and metastatic renal cell carcinoma cell lines

Yoshio Ohno, Miki Izumi, Masaaki Tachibana, Takeshi Kawamura, Kunihiko Yoshioka, Teiichiro Aoyagi, Makoto Ohori, Kazunori Namiki, Noboru Sakamoto, Yoshihiro Nakagami, Tadashi Hatano, Shingo Akimoto, Toshihide Nishimura
Pages: 501-509
Published online on: 01 September 2008

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Article

Prognostic significance of tenascin-C expression in clear cell renal cell carcinoma

Yoshio Ohno, Miki Izumi, Kunihiko Yoshioka, Makoto Ohori, Hiroyuki Yonou, Masaaki Tachibana
Pages: 511-516
Published online on: 01 September 2008

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Article Open Access

Efficacy of the combined use of bevacizumab and irinotecan as a postoperative adjuvant chemotherapy in colon carcinoma

Tomoaki Mizobe, Yutaka Ogata, Hidetsugu Murakami, Yoshito Akagi, Nobuya Ishibashi, Shinjirou Mori, Teruo Sasatomi, Kazuo Shirouzu
Pages: 517-523
Published online on: 01 September 2008

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Article

Prognostic value of the co-expression of carbonic anhydrase IX and vascular endothelial growth factor in patients with clear cell renal cell carcinoma

Nguyen Ba Phuoc, Hidetoshi Ehara, Takahiro Gotoh, Masahiro Nakano, Shingo Kamei, Takashi Deguchi, Yoshinobu Hirose
Pages: 525-530
Published online on: 01 September 2008

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Article

Patterns of recurrence and survival in breast cancer

Daniela Navarrete Montalvo, Nicolás González M, María T. Montalvo V, Andrea Jiménez A, Carlos Echiburú-Chau, Gloria M. Calaf
Pages: 531-535
Published online on: 01 September 2008

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Article

No relationship between 18F-fluorodeoxyglucose positron emission tomography and expression of Glut-1 and -3 and hexokinase I and II in high-grade glioma

N. Charnley, R. Airley, D. Du Plessis, C. West, C. Brock, C. Barnett, J. Matthews, K. Symonds, M. Bottomly, R. Swindell, P. Price
Pages: 537-542
Published online on: 01 September 2008

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Article

GFP image analysis in the mouse orthotopic bladder cancer model

Marco A. De Velasco, Motoyoshi Tanaka, Satoshi Anai, Atsushi Tomioka, Kazuto Nishio, Hirotsugu Uemura
Pages: 543-547
Published online on: 01 September 2008

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Article

Serum amyloid A mediates the inhibitory effect of Ganoderma lucidum polysaccharides on tumor cell adhesion to endothelial cells

Ying-Bo Li, Rui Wang, Hong-Li Wu, Yu-Hua Li, Li-Jun Zhong, He-Ming Yu, Xue-Jun Li
Pages: 549-556
Published online on: 01 September 2008

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Article

Long exposure of non-cytotoxic concentrations of methylselenol suppresses the invasive potential of B16F10 melanoma

Aeyung Kim, Ji-Yong Jung, Minsik Son, Sang-Han Lee, Jong-Seok Lim, An-Sik Chung
Pages: 557-565
Published online on: 01 September 2008

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Article

PJ34, an inhibitor of PARP-1, suppresses cell growth and enhances the suppressive effects of cisplatin in liver cancer cells

Sheng-Hui Huang, Min Xiong, Xiao-Ping Chen, Zhen-Yu Xiao, Yin-Feng Zhao, Zhi-Yong Huang
Pages: 567-572
Published online on: 01 September 2008

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Article

Reduced expression of PDCD5 is associated with high-grade astrocytic gliomas

Haiyan Li, Qun Wang, Fei Gao, Faliang Zhu, Xiaoyan Wang, Chengjun Zhou, Chunmei Liu, Yingyu Chen, Chunhong Ma, Wensheng Sun, Lining Zhang
Pages: 573-579
Published online on: 01 September 2008

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Article

Synergistic inhibitory activity of zoledronate and paclitaxel on bone metastasis in nude mice

Shun Lu, Jie Zhang, Zhen Zhou, Mei-Lin Liao, Wei-Zhong He, Xiao-Yan Zhou, Zi-Ming Li, Jia-Qing Xiang, Jie-Jun Wang, Hai-Quan Chen
Pages: 581-587
Published online on: 01 September 2008

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Article Open Access

Skp2, p27kip1 and EGFR assessment in head and neck squamous cell carcinoma: Prognostic implications

Dario G. Carracedo, Aurora Astudillo, Juan P. Rodrigo, Carlos Suarez, Maria Victoria Gonzalez
Pages: 589-595
Published online on: 01 September 2008

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Article

Significance of p-STAT3 expression in human colorectal adenocarcinoma

Jae-Kyoung Park, Ran Hong, Kyung-Jong Kim, Tae-Bum Lee, Sung-Chul Lim
Pages: 597-604
Published online on: 01 September 2008

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Article

Induction of apoptosis and cell cycle arrest by NS398 in oral squamous cell carcinoma cells via downregulation of E2 promoter-binding factor-1

Yifei Du, Shuangyue Zhang, Zilu Wang, Weina Zhou, Mingliang Luan, Xiaohan Yang, Ning Chen
Pages: 605-611
Published online on: 01 September 2008

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Article

Overexpression of telomerase-associated chaperone proteins in prostatic intraepithelial neoplasia and carcinomas

Lynne W. Elmore, Robert Forsythe, Heidi Forsythe, A. Taylor Bright, Suhail Nasim, Kanendori Endo, Shawn E. Holt
Pages: 613-617
Published online on: 01 September 2008

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Article

Frequent down-regulation of pim-1 mRNA expression in non-small cell lung cancer is associated with lymph node metastases

Ute Warnecke-Eberz, Elfriede Bollschweiler, Uta Drebber, Alexandra Pohl, Stephan E. Baldus, Arnulf H. Hoelscher, Ralf Metzger
Pages: 619-624
Published online on: 01 September 2008

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Article

Linalool, a plant-derived monoterpene alcohol, reverses doxorubicin resistance in human breast adenocarcinoma cells

Raffaella Ravizza, Marzia B. Gariboldi, Roberta Molteni, Elena Monti
Pages: 625-630
Published online on: 01 September 2008

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Article

Integrin αvβ3 is not significantly implicated in the anti-migratory effect of anti-angiogenic urokinase kringle domain

Eunju O, Hyun-Kyung Kim, Sung Hee Hong, Chung Kwon Kim, Yong-Kil Hong, Young Ae Joe
Pages: 631-636
Published online on: 01 September 2008

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Article

Role of p38 MAPK and JNK in enhanced cervical cancer cell killing by the combination of arsenic trioxide and ionizing radiation

Young-Hee Kang, Su-Jae Lee
Pages: 637-643
Published online on: 01 September 2008

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Article

In vitro susceptibility to anticancer agents of the human KB carcinoma cell line transfected with COX-2 cDNA

Kazuki Takaoka, Hiromitsu Kishimoto, Emi Segawa, Nao Otsu, Yusuke Zushi, Susumu Hashitani, Kazuma Noguchi, Masahiro Urade
Pages: 645-649
Published online on: 01 September 2008

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Article

Long-term effects of multimodal treatment for patients with resectable carcinoma of the pancreas

Takehiro Okabayashi, Isao Nishimori, Akihito Nishioka, Koichi Yamashita, Takeki Sugimoto, Ken Dabanaka, Hiromichi Maeda, Takuhiro Kohsaki, Yasuhiro Ogawa, Michiya Kobayashi, Saburo Onishi, Kazuhiro Hanazaki
Pages: 651-656
Published online on: 01 September 2008

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Article

Analysis of caspase activities in rat mammary tumours induced by N-methyl-nitrosourea

M. A. Puertollano, M. P. Carrera, E. Puertollano, G. Álvarez de Cienfuegos, M. J. Ramirez-Expósito, M. A. De Pablo, J. M. Martinez-Martos
Pages: 657-662
Published online on: 01 September 2008

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Article

Oral squamous cell carcinomas stimulate osteoclast differentiation

Yoshiaki Deyama, Kanchu Tei, Yoshitaka Yoshimura, Yuri Izumiyama, Sadaaki Takeyama, Mitsutoki Hatta, Yasunori Totsuka, Kuniaki Suzuki
Pages: 663-668
Published online on: 01 September 2008

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Article

Screening cellular proteins involved in the anti-proliferative effect of the ADAM15 disintegrin domain in murine melanoma cells

Jing Wu, Lianfen Zhang, Xiaofeng Ma, Xiaoping Zhang, Jian Jin
Pages: 669-675
Published online on: 01 September 2008

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Article

Characterization of regulatory T cells in patients with B-cell chronic lymphocytic leukemia

Krzysztof Giannopoulos, Michael Schmitt, Malgorzata Kowal, Paulina Wlasiuk, Agnieszka Bojarska-Junak, Jinfei Chen, Jacek Rolinski, Anna Dmoszynska
Pages: 677-682
Published online on: 01 September 2008

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Article

The prevalence of mtDNA4977 deletion in primary human endometrial carcinomas and matched control samples

Konrad Futyma, Lechoslaw Putowski, Marek Cybulski, Pawel Miotla, Tomasz Rechberger, Andrzej Semczuk
Pages: 683-688
Published online on: 01 September 2008

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Article

Antimycin A as a mitochondrial electron transport inhibitor prevents the growth of human lung cancer A549 cells

Yong Hwan Han, Suhn Hee Kim, Sung Zoo Kim, Woo Hyun Park
Pages: 689-693
Published online on: 01 September 2008

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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