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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2013 Volume 43 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Network-based approaches for anticancer therapy (Review)

Hyunjeong Seo, Wanyeon Kim, Jihyung Lee, Buhyun Youn
Pages: 1737-1744
Published online on: 30 September 2013

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Review

Preoperative treatment of locally advanced esophageal carcinoma (Review)

Michele Orditura, Gennaro Galizia, Alessio Fabozzi, Eva Lieto, Valentina Gambardella, Floriana Morgillo, Gian Mattia Del Genio, Landino Fei, Natale Di Martino, Andrea Renda, Fortunato Ciardiello, Ferdinando De Vita
Pages: 1745-1753
Published online on: 02 October 2013

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Review

Relevance of infection with human papillomavirus: The role of the p53 tumor suppressor protein and E6/E7 zinc finger proteins (Review)

Branislav Ruttkay-Nedecky, Ana Maria Jimenez Jimenez, Lukas Nejdl, Dagmar Chudobova, Jaromir Gumulec, Michal Masarik, Vojtech Adam, Rene Kizek
Pages: 1754-1762
Published online on: 17 September 2013

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Article Open Access

Simvastatin reduces melanoma progression in a murine model

Mario Zanfardino, Carmine Spampanato, Rosanna De Cicco, Elisabetta Buommino, Anna De Filippis, Salvatore Baiano, Adriano Barra, Franco Morelli
Pages: 1763-1770
Published online on: 04 October 2013

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Article Open Access

Oligodendroglioma cells synthesize the differentiation-specific linker histone H1˚ and release it into the extracellular environment through shed vesicles

Gabriella Schiera, Carlo Maria Di Liegro, Patrizia Saladino, Rosario Pitti, Giovanni Savettieri, Patrizia Proia, Italia Di Liegro
Pages: 1771-1776
Published online on: 01 October 2013

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Article Open Access

Suppression of the death gene BIK is a critical factor for resistance to tamoxifen in MCF-7 breast cancer cells Retraction in /10.3892/ijo.2025.5842

Rubí Viedma-Rodriguez, Luis Arturo Baiza-Gutman, Alejandro García-Carrancá, Leticia Moreno-Fierros, Fabio Salamanca-Gómez, Diego Arenas-Aranda
Pages: 1777-1786
Published online on: 04 October 2013

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Article Open Access

In vitro modulation of MMP-2 and MMP-9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors

M. W. Roomi, T. Kalinovsky, J. Monterrey, M. Rath, A. Niedzwiecki
Pages: 1787-1798
Published online on: 30 September 2013

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Article Open Access

Involvement of ER stress in apoptosis induced by sialic acid-binding lectin (leczyme) from bullfrog eggs

Takeo Tatsuta, Masahiro Hosono, Yuki Miura, Shigeki Sugawara, Yukiko Kariya, Senitiroh Hakomori, Kazuo Nitta
Pages: 1799-1808
Published online on: 04 October 2013

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Article Open Access

Hypoxia reduces CD138 expression and induces an immature and stem cell-like transcriptional program in myeloma cells

Yawara Kawano, Yoshitaka Kikukawa, Shiho Fujiwara, Naoko Wada, Yutaka Okuno, Hiroaki Mitsuya, Hiroyuki Hata
Pages: 1809-1816
Published online on: 10 October 2013

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Article Open Access

P53 regulates the migration of mesenchymal stromal cells in response to the tumor microenvironment through both CXCL12-dependent and -independent mechanisms

Siang-Yo Lin, Sonia C. Dolfi, Sohrab Amiri, Jaidong Li, Tulin Budak-Alpdogan, Kuo-Chieh Lee, Christopher Derenzo, Debabrata Banerjee, John Glod
Pages: 1817-1823
Published online on: 23 September 2013

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Article Open Access

Potent antitumor activity of the novel HSP90 inhibitors AUY922 and HSP990 in neuroendocrine carcinoid cells

Kathrin Zitzmann, Galina Ailer, George Vlotides, Gerald Spoettl, Julian Maurer, Burkhard Göke, Felix Beuschlein, Christoph J. Auernhammer
Pages: 1824-1832
Published online on: 04 October 2013

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Article Open Access

Case-control study of the association between malignant brain tumours diagnosed between 2007 and 2009 and mobile and cordless phone use

Lennart Hardell, Michael Carlberg, Fredrik Söderqvist, Kjell Hansson Mild
Pages: 1833-1845
Published online on: 24 September 2013

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Article Open Access

Effect of metformin on residual cells after chemotherapy in a human lung adenocarcinoma cell line

Satoru Kitazono, Yuichi Takiguchi, Hironori Ashinuma, Miyako Saito-Kitazono, Atsushi Kitamura, Tetsuhiro Chiba, Emiko Sakaida, Ikuo Sekine, Yuji Tada, Katsushi Kurosu, Seiichiro Sakao, Nobuhiro Tanabe, Atsushi Iwama, Osamu Yokosuka, Koichiro Tatsumi
Pages: 1846-1854
Published online on: 03 October 2013

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Article Open Access

Tumor-suppressive microRNA-29a inhibits cancer cell migration and invasion via targeting HSP47 in cervical squamous cell carcinoma

Noriko Yamamoto, Takashi Kinoshita, Nijiro Nohata, Hirofumi Yoshino, Toshihiko Itesako, Lisa Fujimura, Akira Mitsuhashi, Hirokazu Usui, Hideki Enokida, Masayuki Nakagawa, Makio Shozu, Naohiko Seki
Pages: 1855-1863
Published online on: 18 October 2013

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Article

Protein O-fucosyltransferase 1: A potential diagnostic marker and therapeutic target for human oral cancer

Satoshi Yokota, Katsunori Ogawara, Ryota Kimura, Fumie Shimizu, Takao Baba, Yasuyuki Minakawa, Morihiro Higo, Atsushi Kasamatsu, Yosuke Endo-Sakamoto, Masashi Shiiba, Hideki Tanzawa, Katsuhiro Uzawa
Pages: 1864-1870
Published online on: 23 September 2013

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Article

Investigating a pathogenic role for TXNDC5 in tumors

Xiaotian Chang, Bing Xu, Lin Wang, Yao Wang, Yuejian Wang, Suhua Yan
Pages: 1871-1884
Published online on: 03 October 2013

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Article

Downregulation of CD147 expression by RNA interference inhibits HT29 cell proliferation, invasion and tumorigenicity in vitro and in vivo

Rui Li, Yuqin Pan, Bangshun He, Yeqiong Xu, Tianyi Gao, Guoqi Song, Huiling Sun, Qiwen Deng, Shukui Wang
Pages: 1885-1894
Published online on: 23 September 2013

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Article

Parthenolide induces superoxide anion production by stimulating EGF receptor in MDA-MB-231 breast cancer cells

A. D'Anneo, D. Carlisi, S. Emanuele, G. Buttitta, R. Di Fiore, R. Vento, G. Tesoriere, M. Lauricella
Pages: 1895-1900
Published online on: 14 October 2013

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Article

Procyanidin C1 from Cinnamomi Cortex inhibits TGF-β-induced epithelial-to-mesenchymal transition in the A549 lung cancer cell line

Ryoei Kin, Shinichiro Kato, Naoki Kaneto, Hiroaki Sakurai, Yoshihiro Hayakawa, Feng Li, Ken Tanaka, Ikuo Saiki, Satoru Yokoyama
Pages: 1901-1906
Published online on: 16 October 2013

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Article

Compound K, a metabolite of ginseng saponin, inhibits colorectal cancer cell growth and induces apoptosis through inhibition of histone deacetylase activity

Kyoung Ah Kang, Mei Jing Piao, Ki Cheon Kim, Jian Zheng, Cheng Wen Yao, Ji Won Cha, Hye Sun Kim, Dong Hyun Kim, Suk Chul Bae, Jin Won Hyun
Pages: 1907-1914
Published online on: 04 October 2013

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Article

A novel resveratrol analogue, HS-1793, inhibits hypoxia-induced HIF-1α and VEGF expression, and migration in human prostate cancer cells

Dong Hwan Kim, Mohammad Akbar Hossain, Min Young Kim, Jin-Ah Kim, Jeong-Hyun Yoon, Hong Suk Suh, Gi-Young Kim, Yung Hyun Choi, Hae Young Chung, Nam Deuk Kim
Pages: 1915-1924
Published online on: 02 October 2013

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Article

Differential BCCIP gene expression in primary human ovarian cancer, renal cell carcinoma and colorectal cancer tissues

Xiaoxia Liu, Lingling Cao, Jinsong Ni, Ning Liu, Xiaoming Zhao, Yanfang Wang, Lin Zhu, Lingyao Wang, Jin Wang, Ying Yue, Yong Cai, Jingji Jin
Pages: 1925-1934
Published online on: 03 October 2013

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Article

Induction of p53 expression and apoptosis by a recombinant dual-target MDM2/MDMX inhibitory protein in wild‑type p53 breast cancer cells

Qian-Qian Geng, Dan-Feng Dong, Nan-Zheng Chen, Yin-Ying Wu, En-Xiao Li, Jie Wang, Shao-Meng Wang
Pages: 1935-1942
Published online on: 14 October 2013

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Article

Oleifolioside B-mediated autophagy promotes apoptosis in A549 human non-small cell lung cancer cells

Cheng-Yun Jin, Hai Yang Yu, Cheol Park, Min Ho Han, Su Hyun Hong, Kyoung-Sook Kim, Young-Choon Lee, Young-Chae Chang, Jaehun Cheong, Sung-Kwon Moon, Gi-Young Kim, Hyung-In Moon, Wun-Jae Kim, Jai-Heon Lee, Yung Hyun Choi
Pages: 1943-1950
Published online on: 17 October 2013

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Article

Curcumin suppresses proliferation and induces apoptosis of human hepatocellular carcinoma cells via the wnt signaling pathway

Marvin Xuejun Xu, Linlin Zhao, Chaoyang Deng, Lu Yang, Yang Wang, Tao Guo, Lifang Li, Jianping Lin, Lirong Zhang
Pages: 1951-1959
Published online on: 23 September 2013

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Article

Aberrant expression of the PRAC gene in prostate cancer

Govinda Lenka, Wen-Hui Weng, Cheng-Keng Chuang, Kwai-Fong Ng, See-Tong Pang
Pages: 1960-1966
Published online on: 02 October 2013

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Article

Notch1-dependent regulation of p27 determines cell fate in colorectal cancer

Nevyana R. Hristova, Katrin E. Tagscherer, Anne Fassl, Juergen Kopitz, Wilfried Roth
Pages: 1967-1975
Published online on: 17 October 2013

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Article

Cytotoxicity of Vitex agnus-castus fruit extract and its major component, casticin, correlates with differentiation status in leukemia cell lines

Hidetomo Kikuchi, Bo Yuan, Yoshio Nishimura, Masahiko Imai, Ryota Furutani, Saki Kamoi, Misako Seno, Shin Fukushima, Shingo Hazama, Chieko Hirobe, Kunio Ohyama, Xiao-Mei Hu, Norio Takagi, Toshihiko Hirano, Hiroo Toyoda
Pages: 1976-1984
Published online on: 09 October 2013

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Article

Establishment of a 5-fluorouracil-resistant triple-negative breast cancer cell line

Katsuyuki Takahashi, Masako Tanaka, Azusa Inagaki, Hideki Wanibuchi, Yasukatsu Izumi, Katsuyuki Miura, Katsuya Nagayama, Masayuki Shiota, Hiroshi Iwao
Pages: 1985-1991
Published online on: 10 October 2013

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Article

Regulation of YAP through an Akt-dependent process by 3, 3'-diindolylmethane in human colon cancer cells

Xiu Juan Li, Sun-Hee Leem, Man Hee Park, Soo Mi Kim
Pages: 1992-1998
Published online on: 03 October 2013

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Article

Resveratrol enhances ionizing radiation-induced premature senescence in lung cancer cells

Hongmei Luo, Lu Wang, Bradley A. Schulte, Aimin Yang, Shengsong Tang, Gavin Y. Wang
Pages: 1999-2006
Published online on: 17 October 2013

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Article

Lentivirus-mediated shRNA targeting of cyclin D1 enhances the chemosensitivity of human gastric cancer to 5-fluorouracil

Jin-Hee Seo, Eui-Suk Jeong, Kyoung-Sun Lee, Seung-Ho Heo, Dong-Gu Jeong, Yang-Kyu Choi
Pages: 2007-2014
Published online on: 03 October 2013

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Article Open Access

Functional impact of colorectal cancer-associated mutations in the transcription factor E2F4

Marie-Christine Paquin, Caroline Leblanc, Etienne Lemieux, Benjamin Bian, Nathalie Rivard
Pages: 2015-2022
Published online on: 08 October 2013

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Article

Intradermal immunization with combined baculovirus and tumor cell lysate induces effective antitumor immunity in mice

Mamoru Kawahara, Hiroshi Takaku
Pages: 2023-2030
Published online on: 04 October 2013

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Article

Autophagy sensitivity of neuroendocrine lung tumor cells

Seung-Keun Hong, Jin-Hwan Kim, Dmytro Starenki, Jong-In Park
Pages: 2031-2038
Published online on: 11 October 2013

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Article

Regulation of estrogen receptor β1 expression in breast cancer by epigenetic modification of the 5' regulatory region

Hakeemah Al-Nakhle, Laura Smith, Sandra M. Bell, Philip A. Burns, Michele Cummings, Andrew M. Hanby, Sally Lane, Marie D. Parker, Thomas A. Hughes, Valerie Speirs
Pages: 2039-2045
Published online on: 25 September 2013

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Article

Involvement of histone H3 phosphorylation through p38 MAPK pathway activation in casticin-induced cytocidal effects against the human promyelocytic cell line HL-60

Hidetomo Kikuchi, Bo Yuan, Eisuke Yuhara, Norio Takagi, Hiroo Toyoda
Pages: 2046-2056
Published online on: 20 September 2013

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Article

Phase II trial of dose-dense chemotherapy followed by dose-intense erlotinib for patients with newly diagnosed metastatic non-small cell lung cancer

W. Jeffrey Petty, Jennifer Laudadio, Lynsay Brautnick, James Lovato, Travis Dotson, Nathan P. Streer, Kathryn E. Weaver, Antonius A. Miller
Pages: 2057-2063
Published online on: 03 October 2013

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Article

Increased killing of SCCVII squamous cell carcinoma cells after the combination of Pc 4 photodynamic therapy and dasatinib is associated with enhanced caspase-3 activity and ceramide synthase 1 upregulation

Duska Separovic, Paul Breen, Nithin B. Boppana, Eric Van Buren, Nicholas Joseph, Jacqueline M. Kraveka, Mehrdad Rahmaniyan, Li Li, Tatyana I. Gudz, Alicja Bielawska, Aiping Bai, Jacek Bielawski, Jason S. Pierce, Mladen Korbelik
Pages: 2064-2072
Published online on: 09 October 2013

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Article

Establishment and characterization of seven human breast cancer cell lines including two triple-negative cell lines

Ja-Lok Ku, Sung-Chan Park, Kyung-Hee Kim, You-Kyung Jeon, Sung-Hee Kim, Young-Kyoung Shin, Dong-Young Noh, Seock-Ah Im, Yung-Jue Bang, Wonshik Han, Woo Ho Kim, Jae-Gahb Park
Pages: 2073-2081
Published online on: 18 October 2013

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Article

CDCA7L promotes hepatocellular carcinoma progression by regulating the cell cycle

Yuan Tian, Changjun Huang, Hai Zhang, Qingfeng Ni, Sheng Han, Dong Wang, Zeguang Han, Xiangcheng Li
Pages: 2082-2090
Published online on: 17 October 2013

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Journal Cover
March-2026 Volume 68 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Circ72309 modulates gemcitabine metabolism and gemcitabine sensitivity in pancreatic cancer: Serum Circ72309 levels as a potential predictor of treatment response

Naoko Sekiguchi, Hidenori Takahashi, Shogo Kobayashi, Kazuki Sasaki, Shinichiro Hasegawa, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Hirofumi Akita, Tadafumi Asaoka, Takehiro Noda, Junzo Shimizu, Koji Tanaka, Ryota Chijimatsu, Yuichiro Doki, Hidetoshi Eguchi
Article Number: 36
Published online on: 16 January 2026

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Review Open Access

Unveiling sex differences in pancreatic ductal adenocarcinoma: Current evidence and future directions (Review)

Sophie Rauschenberg, Elisabeth Orgler‑Gasche, Didem Karakas Zeybek, Ivonne Regel, J.-Matthias Löhr, Daniel Öhlund, Michael Günther, Lina Aguilera Munoz
Article Number: 35
Published online on: 15 January 2026

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Retraction Open Access

[Retracted] LTBP2 promotes the migration and invasion of gastric cancer cells and predicts poor outcome of patients with gastric cancer

Jun Wang, Wen-Jia Liang, Guang-Tao Min, Hong-Peng Wang, Wei Chen, Nan Yao
Article Number: 34
Published online on: 13 January 2026

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Article Open Access

KMO downregulation promotes hepatocellular carcinoma growth via 3‑HAA‑mediated mitochondrial mass and function imbalances

Ming Liu, Xintong Zhang, Yanfen Hu, Li Niu, Linzhi Guo, Guoqing Zhao, Fan Lu, Fengfeng Jia, Li Li, Hao Wu, Jianjun Zhu
Article Number: 33
Published online on: 13 January 2026

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Review Open Access

Regulatory networks of HIFs in tumor‑infiltrating immune cells: From molecular mechanisms to therapeutic implications (Review)

Chaoqun Li, Chenge Qin, Xingchen Li, Jinzhu Wang, Yang Li, Qin Sun
Article Number: 32
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] uPAR and cathepsin B knockdown inhibits radiation‑induced PKC integrated integrin signaling to the cytoskeleton of glioma‑initiating cells

Kiranmai Alapati, Sreelatha Gopinath, Rama Rao Malla, Venkata Ramesh Dasari, Jasti S. Rao
Article Number: 31
Published online on: 05 January 2026

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Article Open Access

PTPN18 functions as a tumor suppressor in breast cancer by negatively regulating cyclin E

Na Zhang, Tao Wang, Bin Bai, Xiaonan Zhang, Wenying Xu, Weilu Chen, Yang Yu, Bing Wang
Article Number: 30
Published online on: 30 December 2025

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Retraction Open Access

[Retracted] Suppression of the death gene BIK is a critical factor for resistance to tamoxifen in MCF‑7 breast cancer cells

Rubí Viedma-Rodriguez, Luis Arturo Baiza-Gutman, Alejandro García-Carrancá, Leticia Moreno-Fierros, Fabio Salamanca-Gómez, Diego Arenas-Aranda
Article Number: 29
Published online on: 23 December 2025

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Review Open Access

Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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