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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-2019 Volume 54 Issue 1

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

IL-21R functions as an oncogenic factor and is regulated by the lncRNA MALAT1/miR-125a-3p axis in gastric cancer Corrigendum in /10.3892/ijo.2025.5780

Lei Yan, Jing Zhang, Dong Guo, Ji Ma, Shao-Feng Shui, Xin-Wei Han
Pages: 7-16
Published online on: 31 October 2018

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Article Open Access

Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis Retraction in /10.3892/ijo.2026.5862

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Pages: 17-28
Published online on: 19 October 2018

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Article Open Access

Ets-1 drives breast cancer cell angiogenic potential and interactions between breast cancer and endothelial cells

Alessandro Furlan, Chantal Vercamer, Laurent Heliot, Nicolas Wernert, Xavier Desbiens, Albin Pourtier
Pages: 29-40
Published online on: 24 October 2018

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Article Open Access

Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesenchymal transition mediated by the FAK/AKT/MMPs axis

Shi‑Quan Liu, Chun‑Yan Xu, Wen‑Hong Wu, Zhen‑Hua Fu, Si‑Wei He, Meng‑Bin Qin, Jie‑An Huang
Pages: 41-52
Published online on: 25 October 2018

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Article Open Access

Dexamethasone-induced inhibition of miR-132 via methylation promotes TGF-β-driven progression of pancreatic cancer Corrigendum in /10.3892/ijo.2023.5543

Alia Abukiwan, Clifford C. Nwaeburu, Nathalie Bauer, Zhefu Zhao, Li Liu, Jury Gladkich, Wolfgang Gross, Axel Benner, Oliver Strobel, Jörg Fellenberg, Ingrid Herr
Pages: 53-64
Published online on: 01 November 2018

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Article Open Access

The novel prognostic marker, EHMT2, is involved in cell proliferation via HSPD1 regulation in breast cancer

Seon‑Kyu Kim, Kwangho Kim, Jea‑Woon Ryu, Tae‑Young Ryu, Jung Hwa Lim, Jung‑Hwa Oh, Jeong‑Ki Min, Cho‑Rok Jung, Ryuji Hamamoto, Mi‑Young Son, Dae‑Soo Kim, Hyun‑Soo Cho
Pages: 65-76
Published online on: 26 October 2018

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Article Open Access

Long non-coding RNA HOTAIR mediates the switching of histone H3 lysine 27 acetylation to methylation to promote epithelial-to-mesenchymal transition in gastric cancer

Yue Song, Rui Wang, Li-Wei Li, Xi Liu, Yun-Fei Wang, Qi-Xue Wang, Qingyu Zhang
Pages: 77-86
Published online on: 05 November 2018

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Article Open Access

Identification of FOXM1 as a specific marker for triple‑negative breast cancer

Yanli Tan, Qixue Wang, Yingbin Xie, Xiaoxia Qiao, Shun Zhang, Yanan Wang, Yongbin Yang, Bo Zhang
Pages: 87-97
Published online on: 19 October 2018

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Article Open Access

Betulinic acid inhibits stemness and EMT of pancreatic cancer cells via activation of AMPK signaling

Liankang Sun, Junyu Cao, Ke Chen, Liang Cheng, Cancan Zhou, Bin Yan, Weikun Qian, Jie Li, Wanxing Duan, Jiguang Ma, Dan Qi, Erxi Wu, Zheng Wang, Qingguang Liu, Qingyong Ma, Qinhong Xu
Pages: 98-110
Published online on: 24 October 2018

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Article Open Access

Comments on the US National Toxicology Program technical reports on toxicology and carcinogenesis study in rats exposed to whole-body radiofrequency radiation at 900 MHz and in mice exposed to whole-body radiofrequency radiation at 1,900 MHz

Lennart Hardell, Michael Carlberg
Pages: 111-127
Published online on: 24 October 2018

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Article Open Access

MicroRNA-98-5p inhibits proliferation and metastasis in non-small cell lung cancer by targeting TGFBR1

Feng Jiang, Qiuhua Yu, Ying Chu, Xiaobo Zhu, Wenbin Lu, Qian Liu, Qiang Wang
Pages: 128-138
Published online on: 29 October 2018

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Article Open Access

HIF-1α contributes to tube malformation of human lymphatic endothelial cells by upregulating VEGFR-3 Corrigendum in /10.3892/ijo.2022.5403

Tao Han, Jun Yan, Haini Chen, Yi Ji, Jianbing Chen, Jie Cui, Weimin Shen, Jijun Zou
Pages: 139-151
Published online on: 05 November 2018

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Article Open Access

Novel drug candidates for treating esophageal carcinoma: A study on differentially expressed genes, using connectivity mapping and molecular docking

Yu‑Ting Chen, Jia‑Yi Xie, Qi Sun, Wei‑Jia Mo
Pages: 152-166
Published online on: 02 November 2018

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Article

Tetramodal therapy using balloon-occluded arterial infusion of anticancer agents, the Azuma regimen, for lymph node-involved bladder cancer

Haruhito Azuma, Teruo Inamoto, Kiyoshi Takahara, Naokazu Ibuki, Hayahito Nomi, Kazumasa Komura, Hirofumi Uehara, Koichiro Minami, Kazuhiro Yamamoto, Yoshifumi Narumi
Pages: 167-176
Published online on: 02 November 2018

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Article

miR‑34a regulates the chemosensitivity of retinoblastoma cells via modulation of MAGE‑A/p53 signaling

Ge Yang, Yang Fu, Xiaoyan Lu, Menghua Wang, Hongtao Dong, Qiuming Li
Pages: 177-187
Published online on: 31 October 2018

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Article

Prolonged survival of renal cancer patients is concomitant with a higher regucalcin gene expression in tumor tissues: Overexpression of regucalcin suppresses the growth of human renal cell carcinoma cells in vitro

Masayoshi Yamaguchi, Satoru Osuka, Oliver Hankinson, Tomiyasu Murata
Pages: 188-198
Published online on: 30 October 2018

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Article

MicroRNA-296, a suppressor non-coding RNA, downregulates SGLT2 expression in lung cancer

Xiaotian Zhang, Xinju Zhang, Xiaomin Liu, Pengfei Qi, Huimin Wang, Zhongliang Ma, Yimin Chai
Pages: 199-208
Published online on: 19 October 2018

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Article

Re‑irradiation plus hyperthermia for recurrent pediatric sarcoma; a simulation study to investigate feasibility

H. Petra Kok, Irma W.E.M. Van Dijk, Koen F. Crama, Nicolaas A.P. Franken, Coen R.N. Rasch, Johannes H.M. Merks, Johannes Crezee, Brian V. Balgobind, Arjan Bel
Pages: 209-218
Published online on: 02 November 2018

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Article

Classification of tumor microenvironment immune types based on immune response-associated gene expression

Ryota Kondou, Akira Iizuka, Chizu Nonomura, Haruo Miyata, Tadashi Ashizawa, Takeshi Nagashima, Keiichi Ohshima, Kenichi Urakami, Masatoshi Kusuhara, Ken Yamaguchi, Yasuto Akiyama
Pages: 219-228
Published online on: 02 November 2018

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Article

Autocrine secretions enhance radioresistance in an exosome‑independent manner in NSCLC cells

Shuang Wang, Piaoyang Gao, Na Li, Ping Chen, Jinhan  Wang, Ningning He, Kaihua Ji, Liqing Du, Qiang Liu
Pages: 229-238
Published online on: 02 November 2018

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Article

LncRNA MALAT1 potentiates autophagy‑associated cisplatin resistance by regulating the microRNA‑30b/autophagy‑related gene 5 axis in gastric cancer

Zhiwen Xi, Jinchun Si, Jun Nan
Pages: 239-248
Published online on: 26 October 2018

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Article

ERp57‑small interfering RNA silencing can enhance the sensitivity of drug‑resistant human ovarian cancer cells to paclitaxel

Shuo Li, Xiaoyun Zhao, Shijie Chang, Yanqiu Li, Min Guo, Yifu Guan
Pages: 249-260
Published online on: 07 November 2018

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Article

AHIF promotes glioblastoma progression and radioresistance via exosomes Expression of Concern in /10.3892/ijo.2026.5883 Corrigendum in /10.3892/ijo.2026.5920

Xuejun Dai, Keman Liao, Zhijun Zhuang, Binghong Chen, Zhiyi Zhou, Sunhai Zhou, Guoshi Lin, Feifei Zhang, Yingying Lin, Yifeng Miao, Zhiqiang Li, Renhua Huang, Yongming Qiu, Ruisheng Lin
Pages: 261-270
Published online on: 02 November 2018

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Article

β‑glucan, a dectin‑1 ligand, promotes macrophage M1 polarization via NF‑κB/autophagy pathway

Xiuying Li, Hongli Luo, Yun Ye, Xuan Chen, Yuhong Zou, Jie Duan, Dong Xiang
Pages: 271-282
Published online on: 09 November 2018

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Article

Nicotine promotes lymph node metastasis and cetuximab resistance in head and neck squamous cell carcinoma

Rieko Shimizu, Soichiro Ibaragi, Takanori Eguchi, Daisuke Kuwajima, Shinichi Kodama, Takashi Nishioka, Tatsuo Okui, Kyoichi Obata, Kiyofumi Takabatake, Hotaka Kawai, Kisho Ono, Kuniaki Okamoto, Hitoshi Nagatsuka, Akira Sasaki
Pages: 283-294
Published online on: 12 November 2018

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Article

Overexpression of lncRNA EGFR‑AS1 is associated with a poor prognosis and promotes chemotherapy resistance in non‑small cell lung cancer Corrigendum in /10.3892/ijo.2019.4686

Yu-Hua Xu, Jian-Ren Tu, Tian-Tian Zhao, Shi-Guang Xie, Sheng-Bo Tang
Pages: 295-305
Published online on: 09 November 2018

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Article

Overexpression of miR‑361‑5p plays an oncogenic role in human lung adenocarcinoma through the regulation of SMAD2

Norahayu Othman, Noor Hasima Nagoor
Pages: 306-314
Published online on: 23 October 2018

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Article

MicroRNA‑766 inhibits papillary thyroid cancer progression by directly targeting insulin receptor substrate 2 and regulating the PI3K/Akt pathway Retraction in /10.3892/ijo.2022.5376

Jianjie Zhao, Zhirong Li, Yi Chen, Shu Zhang, Lingji Guo, Bo Gao, Yan Jiang, Wuguo Tian, Shuai Hao, Xiaohua Zhang
Pages: 315-325
Published online on: 01 November 2018

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Article Open Access

Paclitaxel‑resistant gastric cancer MGC‑803 cells promote epithelial‑to‑mesenchymal transition and chemoresistance in paclitaxel‑sensitive cells via exosomal delivery of miR‑155‑5p

Mei Wang, Rong Qiu, Shaorong Yu, Xiaoyue Xu, Gang  Li, Rongmin Gu, Caihong Tan, Wei Zhu, Bo Shen
Pages: 326-338
Published online on: 22 October 2018

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Article

LncRNA BLACAT1 is involved in chemoresistance of non‑small cell lung cancer cells by regulating autophagy

Feng‑Xiang Huang, Hong‑Jie Chen, Fu‑Xia Zheng, Zeng‑Yan Gao, Pan‑Feng Sun, Qiang Peng, Ying Liu, Xiang Deng, Ya‑Hui Huang, Chang Zhao, Li‑Jun Miao
Pages: 339-347
Published online on: 31 October 2018

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Article Open Access

Expression and epigenetic regulatory mechanism of BNIP3 in clear cell renal cell carcinoma

Yanxiang Shao, Zhenhua Liu, Jianbang Liu, Haizhou Wang, Long Huang, Tianhai Lin, Jiyan Liu, Qiang Wei, Hao Zeng, Gu He, Xiang Li
Pages: 348-360
Published online on: 24 October 2018

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Article

miR‑494.3p expression in synovial sarcoma: Role of CXCR4 as a potential target gene

Laura Pazzaglia, Serena Pollino, Mattia Vitale, Elisa Bientinesi, Stefania Benini, Cristina Ferrari, Emanuela Palmerini, Marco Gambarotti, Piero Picci, Maria Serena Benassi
Pages: 361-369
Published online on: 06 November 2018

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Article

EGFR mutation decreases FDG uptake in non‑small cell lung cancer via the NOX4/ROS/GLUT1 axis

Long Chen, Yongchun Zhou, Xiaoxia Tang, Conghui Yang, Yadong Tian, Ran Xie, Ting Chen, Jiapeng Yang, Mingwei Jing, Fukun Chen, Chun Wang, Hua Sun, Yunchao Huang
Pages: 370-380
Published online on: 06 November 2018

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Article

DOK7V1 influences the malignant phenotype of lung cancer cells through PI3K/AKT/mTOR and FAK/paxillin signaling pathways

Huishan Zhao, Gang Chen, Lin Ye, Hefen Yu, Shenglan Li, Wen G. Jiang
Pages: 381-389
Published online on: 05 November 2018

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Article

VEGI174 protein and its functional domain peptides exert antitumour effects on renal cell carcinoma

Qiang Zhao, Baoan Hong, Tiezhu Liu, Yongpeng Ji, Xinxin Tang, Kan Gong, Lin Ye, Yong Yang, Ning Zhang
Pages: 390-398
Published online on: 12 November 2018

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Journal Cover
October-2026 Volume 69 Issue 4

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

MicroRNA regulation of macrophage polarization in lung cancer: Regulatory networks and therapeutic potential (Review)

Zhao Yiming, Li Jie
Article Number: 121
Published online on: 02 September 2026

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Article Open Access

Effect of xeroderma pigmentosum group C on the characteristics and regulatory mechanisms of lung cancer stem cells

Ben Yang, Yang Yang, Weiyu Wang, Yubing Wang, Huaijie Wang, Liya Qin, Yongming Wang, Sipeng Sun, Shubo Wang, Meihua Qu
Article Number: 120
Published online on: 01 September 2026

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Review Open Access

Post‑translational modification‑governed immune states in cancer immunity: Biomarker implications for checkpoint competence, tumor visibility and immunotherapy resistance (Review)

Jinghao Pan, Boyang Li, Ruonan Lin, Chenlu Fang, Lucy Yue Lau, Zehao Hong, Yi Chen
Article Number: 119
Published online on: 21 August 2026

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Correction Open Access

[Corrigendum] Sulforaphane reduces molecular response to hypoxia in ovarian tumor cells independently of their resistance to chemotherapy

Michal Pastorek, Veronika Simko, Martina Takacova, Monika Barathova, Maria Bartosova, Luba Hunakova, Olga Sedlakova, Sona Hudecova, Olga Krizanova, Franck Dequiedt, Silvia Pastorekova, Jan Sedlak
Article Number: 118
Published online on: 20 August 2026

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Article Open Access

Single in situ intratumoral low‑dose shikonin hydrogel plus mild photothermal therapy elicits systemic antitumor immunity in immune‑cold triple‑negative breast cancer

Tao Pan, Zujian Feng, Ting Shang, Jun Jiang, Fang Zhang
Article Number: 117
Published online on: 19 August 2026

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Article Open Access

KIAA1429 knockdown alleviates osteosarcoma  progression by destabilizing SLC7A11 mRNA via m6A methylation to promote ferroptosis

Hui Zeng, Yunyan Zhong, Dingbiao Zeng, Shiliang Xiao, Song Zou
Article Number: 116
Published online on: 17 August 2026

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Correction Open Access

[Corrigendum] Tanshinone I effectively induces apoptosis in estrogen receptor‑positive (MCF‑7) and estrogen receptor‑negative (MDA‑MB‑231) breast cancer cells

Irina Tsoy Nizamutdinova, Gyeong Won Lee, Kun Ho Son, Su Jin Jeon, Sam Sik Kang, Yeong Shik Kim, Jae Heun Lee, Han Geuk Seo, Ki Churl Chang, Hye Jung Kim
Article Number: 115
Published online on: 12 August 2026

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Review Open Access

Signaling pathways and targeted therapy in high‑risk refractory thyroid cancer: From bench to bedside (Review)

Jian Wang, Zhi Liu, Qing Zhang, Wei Sun
Article Number: 114
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Downmodulation of dimethyl transferase activity enhances tumor necrosis factor‑related apoptosis‑inducing ligand‑ induced apoptosis in prostate cancer cells

Claudio Festuccia, Giovanni Luca Gravina, Anna Maria D'Alessandro, Danilo Millimaggi, Cristiana Di Rocco, Vincenza Dolo, Enrico Ricevuto, Carlo Vicentini, Mauro Bologna
Article Number: 113
Published online on: 10 August 2026

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Review Open Access

The pivotal role of SCD1 in digestive cancers: Bridging lipid metabolic reprogramming and programmed cell death (Review)

Yangxi Fu, Zheng Wang, Lin Liu, Xudong Tang
Article Number: 112
Published online on: 07 August 2026

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Article Open Access

piR‑164552 promotes malignant progression in head and neck squamous cell carcinoma via the RBM4/EIF4E2 signaling axis: Insights from multi‑omics and functional analyses

Shan Yang, Zhen Shang, Shunxian Xia, Hongbo Liu, Yanhan Dong, Xiaomin Wang, Wenhua Xu, Haijun Lu
Article Number: 111
Published online on: 07 August 2026

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Correction Open Access

[Corrigendum] Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines

Nesstor Pilco‑Ferreto, Gloria   M. Calaf
Article Number: 110
Published online on: 20 July 2026

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Article Open Access

Evaluation of Punicalagin as a multi‑targeted therapeutic agent against endometrial cancer

Zeeshan Ahmad Bhutta, Dohee Ahn, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 109
Published online on: 17 July 2026

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Journal Cover
November-2026 Volume 69 Issue 5

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] In vitro modulation of MMP‑2 and MMP‑9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors

M.W. Roomi, T. Kalinovsky, J.  Monterrey, M. Rath, A. Niedzwiecki
Article Number: 129
Published online on: 21 September 2026

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Review Open Access

Eomesodermin in renal cell carcinoma: Epigenetic and immune crosstalk driving tumor progression (Review)

Zhifei Che, Dongwen Huang, Jiaming Lin, Xincen Wang, Rongjin Feng, Xianping Che, Yubin Wang
Article Number: 128
Published online on: 18 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ultraviolet exposure of melanoma cells induces fibroblast activation protein‑α in fibroblasts: Implications for melanoma invasion

Petra Wäster, Inger Rosdahl, Brendan F.  Gilmore, Oliver Seifert
Article Number: 127
Published online on: 16 September 2026

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Article Open Access

E3 ubiquitin ligase MAGI3‑mediated TAZ ubiquitination suppresses the non‑small cell lung cancer occurrence and development by targeting the Wnt pathway

Ye Liang, Jie Zhuang
Article Number: 126
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] TIP60 governs the auto‑ubiquitination of UHRF1 through USP7 dissociation from the UHRF1/USP7 complex

Tanveer Ahmad, Waseem Ashraf, Abdulkhaleg Ibrahim, Liliyana Zaayter, Christian D. Muller, Ali Hamiche, Yves Mély, Christian Bronner, Marc Mousli
Article Number: 125
Published online on: 14 September 2026

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Correction Open Access

[Corrigendum] miR‑221/222 promote malignant progression of glioma through activation of the Akt pathway

Junxia Zhang, Lei Han, Youlin Ge, Xuan Zhou, Anling Zhang, Chunzhi Zhang, Yue Zhong, Yongping You, Peiyu Pu, Chunsheng Kang
Article Number: 124
Published online on: 03 September 2026

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Review Open Access

Dendritic cell‑based vaccines for colorectal cancer: Mechanisms, clinical progress and future directions (Review)

Lian Yih Pong, Siti Ayuni Hassanudin, Seng Kong Tham, Ravichandran Manickam, Chee Yin Wong, Keat Seong Poh, Chit Laa Poh
Article Number: 123
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Pro‑metastatic intracellular signaling of the elaidic trans fatty acid

Kiyomu Fujii, Yi Luo, Rina Fujiwara-tani, Shingo Kishi, Song He, Shuyun Yang, Takamitsu Sasaki, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 122
Published online on: 02 September 2026

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