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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-2019 Volume 54 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

IL-21R functions as an oncogenic factor and is regulated by the lncRNA MALAT1/miR-125a-3p axis in gastric cancer Corrigendum in /10.3892/ijo.2025.5780

Lei Yan, Jing Zhang, Dong Guo, Ji Ma, Shao-Feng Shui, Xin-Wei Han
Pages: 7-16
Published online on: 31 October 2018

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Article Open Access

Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Pages: 17-28
Published online on: 19 October 2018

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Article Open Access

Ets-1 drives breast cancer cell angiogenic potential and interactions between breast cancer and endothelial cells

Alessandro Furlan, Chantal Vercamer, Laurent Heliot, Nicolas Wernert, Xavier Desbiens, Albin Pourtier
Pages: 29-40
Published online on: 24 October 2018

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Article Open Access

Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesenchymal transition mediated by the FAK/AKT/MMPs axis

Shi‑Quan Liu, Chun‑Yan Xu, Wen‑Hong Wu, Zhen‑Hua Fu, Si‑Wei He, Meng‑Bin Qin, Jie‑An Huang
Pages: 41-52
Published online on: 25 October 2018

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Article Open Access

Dexamethasone-induced inhibition of miR-132 via methylation promotes TGF-β-driven progression of pancreatic cancer Corrigendum in /10.3892/ijo.2023.5543

Alia Abukiwan, Clifford C. Nwaeburu, Nathalie Bauer, Zhefu Zhao, Li Liu, Jury Gladkich, Wolfgang Gross, Axel Benner, Oliver Strobel, Jörg Fellenberg, Ingrid Herr
Pages: 53-64
Published online on: 01 November 2018

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Article Open Access

The novel prognostic marker, EHMT2, is involved in cell proliferation via HSPD1 regulation in breast cancer

Seon‑Kyu Kim, Kwangho Kim, Jea‑Woon Ryu, Tae‑Young Ryu, Jung Hwa Lim, Jung‑Hwa Oh, Jeong‑Ki Min, Cho‑Rok Jung, Ryuji Hamamoto, Mi‑Young Son, Dae‑Soo Kim, Hyun‑Soo Cho
Pages: 65-76
Published online on: 26 October 2018

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Article Open Access

Long non-coding RNA HOTAIR mediates the switching of histone H3 lysine 27 acetylation to methylation to promote epithelial-to-mesenchymal transition in gastric cancer

Yue Song, Rui Wang, Li-Wei Li, Xi Liu, Yun-Fei Wang, Qi-Xue Wang, Qingyu Zhang
Pages: 77-86
Published online on: 05 November 2018

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Article Open Access

Identification of FOXM1 as a specific marker for triple‑negative breast cancer

Yanli Tan, Qixue Wang, Yingbin Xie, Xiaoxia Qiao, Shun Zhang, Yanan Wang, Yongbin Yang, Bo Zhang
Pages: 87-97
Published online on: 19 October 2018

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Article Open Access

Betulinic acid inhibits stemness and EMT of pancreatic cancer cells via activation of AMPK signaling

Liankang Sun, Junyu Cao, Ke Chen, Liang Cheng, Cancan Zhou, Bin Yan, Weikun Qian, Jie Li, Wanxing Duan, Jiguang Ma, Dan Qi, Erxi Wu, Zheng Wang, Qingguang Liu, Qingyong Ma, Qinhong Xu
Pages: 98-110
Published online on: 24 October 2018

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Article Open Access

Comments on the US National Toxicology Program technical reports on toxicology and carcinogenesis study in rats exposed to whole-body radiofrequency radiation at 900 MHz and in mice exposed to whole-body radiofrequency radiation at 1,900 MHz

Lennart Hardell, Michael Carlberg
Pages: 111-127
Published online on: 24 October 2018

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Article Open Access

MicroRNA-98-5p inhibits proliferation and metastasis in non-small cell lung cancer by targeting TGFBR1

Feng Jiang, Qiuhua Yu, Ying Chu, Xiaobo Zhu, Wenbin Lu, Qian Liu, Qiang Wang
Pages: 128-138
Published online on: 29 October 2018

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Article Open Access

HIF-1α contributes to tube malformation of human lymphatic endothelial cells by upregulating VEGFR-3 Corrigendum in /10.3892/ijo.2022.5403

Tao Han, Jun Yan, Haini Chen, Yi Ji, Jianbing Chen, Jie Cui, Weimin Shen, Jijun Zou
Pages: 139-151
Published online on: 05 November 2018

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Article Open Access

Novel drug candidates for treating esophageal carcinoma: A study on differentially expressed genes, using connectivity mapping and molecular docking

Yu‑Ting Chen, Jia‑Yi Xie, Qi Sun, Wei‑Jia Mo
Pages: 152-166
Published online on: 02 November 2018

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Article

Tetramodal therapy using balloon-occluded arterial infusion of anticancer agents, the Azuma regimen, for lymph node-involved bladder cancer

Haruhito Azuma, Teruo Inamoto, Kiyoshi Takahara, Naokazu Ibuki, Hayahito Nomi, Kazumasa Komura, Hirofumi Uehara, Koichiro Minami, Kazuhiro Yamamoto, Yoshifumi Narumi
Pages: 167-176
Published online on: 02 November 2018

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Article

miR‑34a regulates the chemosensitivity of retinoblastoma cells via modulation of MAGE‑A/p53 signaling

Ge Yang, Yang Fu, Xiaoyan Lu, Menghua Wang, Hongtao Dong, Qiuming Li
Pages: 177-187
Published online on: 31 October 2018

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Article

Prolonged survival of renal cancer patients is concomitant with a higher regucalcin gene expression in tumor tissues: Overexpression of regucalcin suppresses the growth of human renal cell carcinoma cells in vitro

Masayoshi Yamaguchi, Satoru Osuka, Oliver Hankinson, Tomiyasu Murata
Pages: 188-198
Published online on: 30 October 2018

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Article

MicroRNA-296, a suppressor non-coding RNA, downregulates SGLT2 expression in lung cancer

Xiaotian Zhang, Xinju Zhang, Xiaomin Liu, Pengfei Qi, Huimin Wang, Zhongliang Ma, Yimin Chai
Pages: 199-208
Published online on: 19 October 2018

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Article

Re‑irradiation plus hyperthermia for recurrent pediatric sarcoma; a simulation study to investigate feasibility

H. Petra Kok, Irma W.E.M. Van Dijk, Koen F. Crama, Nicolaas A.P. Franken, Coen R.N. Rasch, Johannes H.M. Merks, Johannes Crezee, Brian V. Balgobind, Arjan Bel
Pages: 209-218
Published online on: 02 November 2018

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Article

Classification of tumor microenvironment immune types based on immune response-associated gene expression

Ryota Kondou, Akira Iizuka, Chizu Nonomura, Haruo Miyata, Tadashi Ashizawa, Takeshi Nagashima, Keiichi Ohshima, Kenichi Urakami, Masatoshi Kusuhara, Ken Yamaguchi, Yasuto Akiyama
Pages: 219-228
Published online on: 02 November 2018

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Article

Autocrine secretions enhance radioresistance in an exosome‑independent manner in NSCLC cells

Shuang Wang, Piaoyang Gao, Na Li, Ping Chen, Jinhan  Wang, Ningning He, Kaihua Ji, Liqing Du, Qiang Liu
Pages: 229-238
Published online on: 02 November 2018

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Article

LncRNA MALAT1 potentiates autophagy‑associated cisplatin resistance by regulating the microRNA‑30b/autophagy‑related gene 5 axis in gastric cancer

Zhiwen Xi, Jinchun Si, Jun Nan
Pages: 239-248
Published online on: 26 October 2018

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Article

ERp57‑small interfering RNA silencing can enhance the sensitivity of drug‑resistant human ovarian cancer cells to paclitaxel

Shuo Li, Xiaoyun Zhao, Shijie Chang, Yanqiu Li, Min Guo, Yifu Guan
Pages: 249-260
Published online on: 07 November 2018

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Article

AHIF promotes glioblastoma progression and radioresistance via exosomes

Xuejun Dai, Keman Liao, Zhijun Zhuang, Binghong Chen, Zhiyi Zhou, Sunhai Zhou, Guoshi Lin, Feifei Zhang, Yingying Lin, Yifeng Miao, Zhiqiang Li, Renhua Huang, Yongming Qiu, Ruisheng Lin
Pages: 261-270
Published online on: 02 November 2018

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Article

β‑glucan, a dectin‑1 ligand, promotes macrophage M1 polarization via NF‑κB/autophagy pathway

Xiuying Li, Hongli Luo, Yun Ye, Xuan Chen, Yuhong Zou, Jie Duan, Dong Xiang
Pages: 271-282
Published online on: 09 November 2018

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Article

Nicotine promotes lymph node metastasis and cetuximab resistance in head and neck squamous cell carcinoma

Rieko Shimizu, Soichiro Ibaragi, Takanori Eguchi, Daisuke Kuwajima, Shinichi Kodama, Takashi Nishioka, Tatsuo Okui, Kyoichi Obata, Kiyofumi Takabatake, Hotaka Kawai, Kisho Ono, Kuniaki Okamoto, Hitoshi Nagatsuka, Akira Sasaki
Pages: 283-294
Published online on: 12 November 2018

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Article

Overexpression of lncRNA EGFR‑AS1 is associated with a poor prognosis and promotes chemotherapy resistance in non‑small cell lung cancer Corrigendum in /10.3892/ijo.2019.4686

Yu-Hua Xu, Jian-Ren Tu, Tian-Tian Zhao, Shi-Guang Xie, Sheng-Bo Tang
Pages: 295-305
Published online on: 09 November 2018

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Article

Overexpression of miR‑361‑5p plays an oncogenic role in human lung adenocarcinoma through the regulation of SMAD2

Norahayu Othman, Noor Hasima Nagoor
Pages: 306-314
Published online on: 23 October 2018

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Article

MicroRNA‑766 inhibits papillary thyroid cancer progression by directly targeting insulin receptor substrate 2 and regulating the PI3K/Akt pathway Retraction in /10.3892/ijo.2022.5376

Jianjie Zhao, Zhirong Li, Yi Chen, Shu Zhang, Lingji Guo, Bo Gao, Yan Jiang, Wuguo Tian, Shuai Hao, Xiaohua Zhang
Pages: 315-325
Published online on: 01 November 2018

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Article Open Access

Paclitaxel‑resistant gastric cancer MGC‑803 cells promote epithelial‑to‑mesenchymal transition and chemoresistance in paclitaxel‑sensitive cells via exosomal delivery of miR‑155‑5p

Mei Wang, Rong Qiu, Shaorong Yu, Xiaoyue Xu, Gang  Li, Rongmin Gu, Caihong Tan, Wei Zhu, Bo Shen
Pages: 326-338
Published online on: 22 October 2018

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Article

LncRNA BLACAT1 is involved in chemoresistance of non‑small cell lung cancer cells by regulating autophagy

Feng‑Xiang Huang, Hong‑Jie Chen, Fu‑Xia Zheng, Zeng‑Yan Gao, Pan‑Feng Sun, Qiang Peng, Ying Liu, Xiang Deng, Ya‑Hui Huang, Chang Zhao, Li‑Jun Miao
Pages: 339-347
Published online on: 31 October 2018

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Article Open Access

Expression and epigenetic regulatory mechanism of BNIP3 in clear cell renal cell carcinoma

Yanxiang Shao, Zhenhua Liu, Jianbang Liu, Haizhou Wang, Long Huang, Tianhai Lin, Jiyan Liu, Qiang Wei, Hao Zeng, Gu He, Xiang Li
Pages: 348-360
Published online on: 24 October 2018

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Article

miR‑494.3p expression in synovial sarcoma: Role of CXCR4 as a potential target gene

Laura Pazzaglia, Serena Pollino, Mattia Vitale, Elisa Bientinesi, Stefania Benini, Cristina Ferrari, Emanuela Palmerini, Marco Gambarotti, Piero Picci, Maria Serena Benassi
Pages: 361-369
Published online on: 06 November 2018

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Article

EGFR mutation decreases FDG uptake in non‑small cell lung cancer via the NOX4/ROS/GLUT1 axis

Long Chen, Yongchun Zhou, Xiaoxia Tang, Conghui Yang, Yadong Tian, Ran Xie, Ting Chen, Jiapeng Yang, Mingwei Jing, Fukun Chen, Chun Wang, Hua Sun, Yunchao Huang
Pages: 370-380
Published online on: 06 November 2018

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Article

DOK7V1 influences the malignant phenotype of lung cancer cells through PI3K/AKT/mTOR and FAK/paxillin signaling pathways

Huishan Zhao, Gang Chen, Lin Ye, Hefen Yu, Shenglan Li, Wen G. Jiang
Pages: 381-389
Published online on: 05 November 2018

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Article

VEGI174 protein and its functional domain peptides exert antitumour effects on renal cell carcinoma

Qiang Zhao, Baoan Hong, Tiezhu Liu, Yongpeng Ji, Xinxin Tang, Kan Gong, Lin Ye, Yong Yang, Ning Zhang
Pages: 390-398
Published online on: 12 November 2018

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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