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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-April 2010 Volume 3 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

Modulation of ryanodine receptor Ca2+ channels (Review)

Terutaka Ozawa
Pages: 199-204
Published online on: 01 March 2010

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Article

Genetic risk factors of chronic venous leg ulceration: Can molecular screening aid in the prevention of chronic venous insufficiency complications?

Tomasz Grzela, Agata Bialoszewska
Pages: 205-211
Published online on: 01 March 2010

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Gene expression in the adrenal glands of three spontaneously hypertensive rat substrains

Mohammad S. Ashenagar, Masaki Tabuchi, Kosho Kinoshita, Kana Ooshima, Atsuko Niwa, Yuko Watanabe, Momoko Yoshida, Kazunori Shimada, Teruo Yasunaga, Hiromichi Yamanishi, Hideaki Higashino
Pages: 213-222
Published online on: 01 March 2010

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Article Open Access

Novel ETHE1 mutation in a carrier couple having prior offspring affected with ethylmalonic encephalopathy: Genetic analysis, clinical management and reproductive outcome

David J. Walsh, Eric S. Sills, Deborah M. Lambert, Nils Gregersen, Fergal D. Malone, Anthony P.H. Walsh
Pages: 223-226
Published online on: 01 March 2010

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Article

Anti-tumor activity of Sann-Joong-Kuey-Jian-Tang alone and in combination with 5-fluorouracil in a human colon cancer colo 205 cell xenograft model

Chun-Yuan Cheng, Yi-Hsiang Lin, Chin-Cheng Su
Pages: 227-231
Published online on: 01 March 2010

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Article

Expression of sphingosine-1 phosphate receptor in rat renal ischemia-reperfusion injury

Masahide Matsuyama, Kiyoaki Funao, Katsuyuki Kuratsukuri, Tomoaki Tanaka, Yutaka Kawahito, Hajime Sano, Jamel Chargui, Jean-Louis Touraine, Norio Yoshimura, Rikio Yoshimura
Pages: 233-236
Published online on: 01 March 2010

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Article

Evaluation of valid reference genes during stimulation with static magnetic fields in human myoblast cultures

Jens Stern-Straeter, Gabriel A. Bonaterra, Stefanie Zügel, Stefan S. Kassner, Karl Hörmann, Ralf Kinscherf, Ulrich R. Goessler
Pages: 237-243
Published online on: 01 March 2010

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Article

Cysteinyl-leukotriene1 receptor is a potent target for the prevention and treatment of human urological cancer

Masahide Matsuyama, Rikio Yoshimura
Pages: 245-251
Published online on: 01 March 2010

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Article

Optimization of molecular detection of GD2 synthase mRNA in retinoblastoma

Viviana E. Laurent, Laura L. Otero, Valeria Vazquez, Sandra Camarero, Mariano R. Gabri, María Labraga, María T.G. De Dávila, Guillermo L. Chantada, Daniel F. Alonso
Pages: 253-259
Published online on: 01 March 2010

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Article

The intrinsic apoptotic signaling pathway in gastric adenocarcinomas of Brazilian patients: Immunoexpression of the Bcl-2 family (Bcl-2, Bcl-x, Bak, Bax, Bad) determined by tissue microarray analysis

Luis F.M. Barrezueta, Celina T.F. Oshima, Flávio O. Lima, Henrique De Oliveira Costa, Thiago S. Gomes, Ricardo A. Neto, Marcello F. De Franco
Pages: 261-267
Published online on: 01 March 2010

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Article

Tissue factor-factor VIIa regulates interleukin-8, tissue factor and caspase-7 expression in SW620 cells through protease-activated receptor-2 activation

Hong Zhou, Wenxia Shi, Baocheng Zhou, Donglin Guo, Ting Wang
Pages: 269-274
Published online on: 01 March 2010

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Article

Carbamylated albumin stimulates microRNA-146, which is increased in human renal cell carcinoma

Eunyoung Ha, Ji-Hye Bang, Jung N. Son, Ho-Chan Cho, Kyo-Chul Mun
Pages: 275-279
Published online on: 01 March 2010

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Article

Saponified sunflower and safflower oils inhibit melanogenesis in B16 melanoma cells

Jeung-Hyun Koo, Ikjae Lee, Seok-Kweon Yun, Han-Uk Kim, Byung-Hyun Park, Jin-Woo Park
Pages: 281-285
Published online on: 01 March 2010

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Article

Inhibitory effects of cytoplasmic-domain substituted epidermal growth factor receptor on growth, invasion and angiogenesis in human gastric cancer cells

Gang Liao, Ziwei Wang, Lin Zhao, Neng Zhang, Pujiang Dong
Pages: 287-294
Published online on: 01 March 2010

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Article

Lentiviral-mediated Smad4 RNAi promotes SMMC-7721 cell migration by regulation of MMP-2, VEGF and MAPK signaling

Xiaodan Huang, Shu Huang, Faming Zhang, Xiang Han, Lin Miao, Zheng Liu, Zhining Fan, Guozhong Ji
Pages: 295-299
Published online on: 01 March 2010

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Article

Different threshold levels for 2-amino-3,8 dimethylimidazo[4,5-f]quinoxaline (MelQx) initiation of lung and colon carcinogenesis and the effects of an additional initiation by 4 (methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A/J mice

Satoshi Suzuki, Masanao Yokohira, Nozomi Hashimoto, Kousuke Saoo, Yoko Matsuda, Keiko Yamakawa, Yoko Nakano, Toshiya Kuno, Katsumi Imaida
Pages: 301-307
Published online on: 01 March 2010

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Article

Potentiation of the activity of cisplatin in a human colon tumour xenograft model by auristatin PYE, a structural modification of dolastatin 10

Ekatherine M. Prokopiou, Patricia A. Cooper, George R. Pettit, Michael C. Bibby, Steven D. Shnyder
Pages: 309-313
Published online on: 01 March 2010

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Article

Selective anticancer activity of β-lactams derived from polyaromatic compound

Bimal K. Banik, Frederick F. Becker
Pages: 315-316
Published online on: 01 March 2010

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Article

Chemoenzymatic preparation of intermediates for the taxol side chain and analogs

Bimal K. Banik, Mahima Negi, Maghar S. Manhas, Ajay K. Bose
Pages: 317-318
Published online on: 01 March 2010

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Article

Asymmetric synthesis of anticancer β-lactams via Staudinger reaction

Bimal K. Banik, Susanta Samajdar, Frederick F. Becker
Pages: 319-321
Published online on: 01 March 2010

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Article

Adiponectin suppresses inflammatory responses at the early phase of atherosclerosis in hyperglycemic rats

Jin-Bo Liu, Lin Jia, Bing-Rong Li, Li-Zhen Lan, Qian Ge, Hong-Ting Zhen, Hua-Cong Deng
Pages: 323-328
Published online on: 01 March 2010

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Article

Cysteinyl-leukotriene1 receptor antagonist prevents urological cancer cell growth through early apoptosis

Masahide Matsuyama, Kiyoaki Funao, Katsuyuki Kuratukuri, Tomoaki Tanaka, Yutaka Kawahito, Hajime Sano, Norio Yoshimura, Tatsuya Nakatani, Rikio Yoshimura
Pages: 329-332
Published online on: 01 March 2010

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Article

Combined effects of the proteasome inhibitor bortezomib and Hsp70 inhibitors on the B16F10 melanoma cell line

Azmi Yerlikaya, Emrah Okur, Semih Şeker, Nuray Erin
Pages: 333-339
Published online on: 01 March 2010

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Article

A novel putative interactor for the low density lipoprotein receptor cytoplasmic domain

Salvatore Costa, Aldo Nicosia, Maria A. Ragusa, Angelo B. Cefalù, Daniela Pollaccia, Davide Noto, Maurizio Averna, Fabrizio Gianguzza
Pages: 341-345
Published online on: 01 March 2010

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Article

Evaluation of insulin binding and signaling activity of newly synthesized chromium(III) complexes in vitro

Pawel Mackowiak, Zbigniew Krejpcio, Maciej Sassek, Przemyslaw Kaczmarek, Iwona Hertig, Joanna Chmielewska, Tatiana Wojciechowicz, Dawid Szczepankiewicz, Daria Wieczorek, Henryk Szymusiak, Krzysztof W. Nowak
Pages: 347-353
Published online on: 01 March 2010

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Article

CpG islands around exon 1 in the succinyl-CoA:3-ketoacid CoA transferase (SCOT) gene are hypomethylated even in human and mouse hepatic tissues where SCOT gene expression is completely suppressed

Toshiyuki Fukao, Gaixiu Zhang, Naoki Matsuo, Naomi Kondo
Pages: 355-359
Published online on: 01 March 2010

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Article

Type II cGMP-dependent protein kinase inhibits proliferation of the gastric cancer cell line BGC-823

Yong-Chang Chen, Feng Ren, Jian-Rong Sang, Yan Tao, Wen-Rong Xu
Pages: 361-366
Published online on: 01 March 2010

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

CTRP4 ameliorates dexamethasone‑induced insulin resistance through the IRS‑1/PI3K/AKT pathway in 3T3‑L1 adipocytes

Maireyanmu Rouzi, Xi Sun, Luguang Sheng, Bilin Xu, Tao Lei, Jun Lu, Jie Gao
Article Number: 101
Published online on: 27 January 2026

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PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity

Hevna Dhulkifle, Lubna Therachiyil, Maram H. Hasan, Shahd M. Younis, Nizar A. Al‑Shar'i, Huseyin C. Yalcin, Zaid H. Maayah
Article Number: 100
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression

Jianwen Long, Jing Luo, Xuwen Yin
Article Number: 99
Published online on: 26 January 2026

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Review Open Access

Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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Article Open Access

HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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Review

PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Review Open Access

Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Review Open Access

Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Article Open Access

Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Review Open Access

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Circular RNAs in intervertebral disc degeneration: Current insights into mechanisms and therapeutic potentials (Review)

Luyan Wang, Ke Yang, Houjun Zhu, Dachuan Wang, Feng Wang, Xianfa Du
Article Number: 111
Published online on: 05 February 2026

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Review Open Access

T‑cadherin and its impact on human diseases (Review)

Yan Song, Xinyi Wang, Yunfei Bian
Article Number: 110
Published online on: 05 February 2026

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Review

CD20 monoclonal antibody‑rituximab for the treatment of diffuse alveolar hemorrhage in children (Review)

Xiaobo Zhang, Xiao Wu, Yan Li, Guangmin Nong
Article Number: 109
Published online on: 05 February 2026

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N6‑methyladenosine reader insulin‑like growth factor 2 mRNA‑binding protein 2 promotes abnormal proliferation of colonic epithelial cells in type 2 diabetes mellitus by regulating midkine

Jieyao Li, Qingsheng Xie, Jihao Xu
Article Number: 108
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin‑induced VEGF expression

Goutam Chakraborty, Shalini Jain, Smita Kale, Remya Raja, Santosh Kumar, Rosalin Mishra, Gopal C. Kundu
Article Number: 107
Published online on: 04 February 2026

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Review Open Access

Research status and molecular mechanisms of disulfidptosis in cardiovascular diseases (Review)

Xiao Jin, Zelin Cheng, Xinyue Ding, Zongjun Liu
Article Number: 106
Published online on: 03 February 2026

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Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats

Caifen Guo, Jian Li
Article Number: 105
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 104
Published online on: 02 February 2026

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Article Open Access

Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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