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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-April 2010 Volume 3 Issue 2

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

Modulation of ryanodine receptor Ca2+ channels (Review)

Terutaka Ozawa
Pages: 199-204
Published online on: 01 March 2010

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Article

Genetic risk factors of chronic venous leg ulceration: Can molecular screening aid in the prevention of chronic venous insufficiency complications?

Tomasz Grzela, Agata Bialoszewska
Pages: 205-211
Published online on: 01 March 2010

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Article Open Access

Gene expression in the adrenal glands of three spontaneously hypertensive rat substrains

Mohammad S. Ashenagar, Masaki Tabuchi, Kosho Kinoshita, Kana Ooshima, Atsuko Niwa, Yuko Watanabe, Momoko Yoshida, Kazunori Shimada, Teruo Yasunaga, Hiromichi Yamanishi, Hideaki Higashino
Pages: 213-222
Published online on: 01 March 2010

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Article Open Access

Novel ETHE1 mutation in a carrier couple having prior offspring affected with ethylmalonic encephalopathy: Genetic analysis, clinical management and reproductive outcome

David J. Walsh, Eric S. Sills, Deborah M. Lambert, Nils Gregersen, Fergal D. Malone, Anthony P.H. Walsh
Pages: 223-226
Published online on: 01 March 2010

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Article

Anti-tumor activity of Sann-Joong-Kuey-Jian-Tang alone and in combination with 5-fluorouracil in a human colon cancer colo 205 cell xenograft model

Chun-Yuan Cheng, Yi-Hsiang Lin, Chin-Cheng Su
Pages: 227-231
Published online on: 01 March 2010

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Article

Expression of sphingosine-1 phosphate receptor in rat renal ischemia-reperfusion injury

Masahide Matsuyama, Kiyoaki Funao, Katsuyuki Kuratsukuri, Tomoaki Tanaka, Yutaka Kawahito, Hajime Sano, Jamel Chargui, Jean-Louis Touraine, Norio Yoshimura, Rikio Yoshimura
Pages: 233-236
Published online on: 01 March 2010

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Article

Evaluation of valid reference genes during stimulation with static magnetic fields in human myoblast cultures

Jens Stern-Straeter, Gabriel A. Bonaterra, Stefanie Zügel, Stefan S. Kassner, Karl Hörmann, Ralf Kinscherf, Ulrich R. Goessler
Pages: 237-243
Published online on: 01 March 2010

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Article

Cysteinyl-leukotriene1 receptor is a potent target for the prevention and treatment of human urological cancer

Masahide Matsuyama, Rikio Yoshimura
Pages: 245-251
Published online on: 01 March 2010

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Article

Optimization of molecular detection of GD2 synthase mRNA in retinoblastoma

Viviana E. Laurent, Laura L. Otero, Valeria Vazquez, Sandra Camarero, Mariano R. Gabri, María Labraga, María T.G. De Dávila, Guillermo L. Chantada, Daniel F. Alonso
Pages: 253-259
Published online on: 01 March 2010

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Article

The intrinsic apoptotic signaling pathway in gastric adenocarcinomas of Brazilian patients: Immunoexpression of the Bcl-2 family (Bcl-2, Bcl-x, Bak, Bax, Bad) determined by tissue microarray analysis

Luis F.M. Barrezueta, Celina T.F. Oshima, Flávio O. Lima, Henrique De Oliveira Costa, Thiago S. Gomes, Ricardo A. Neto, Marcello F. De Franco
Pages: 261-267
Published online on: 01 March 2010

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Article

Tissue factor-factor VIIa regulates interleukin-8, tissue factor and caspase-7 expression in SW620 cells through protease-activated receptor-2 activation

Hong Zhou, Wenxia Shi, Baocheng Zhou, Donglin Guo, Ting Wang
Pages: 269-274
Published online on: 01 March 2010

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Article

Carbamylated albumin stimulates microRNA-146, which is increased in human renal cell carcinoma

Eunyoung Ha, Ji-Hye Bang, Jung N. Son, Ho-Chan Cho, Kyo-Chul Mun
Pages: 275-279
Published online on: 01 March 2010

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Article

Saponified sunflower and safflower oils inhibit melanogenesis in B16 melanoma cells

Jeung-Hyun Koo, Ikjae Lee, Seok-Kweon Yun, Han-Uk Kim, Byung-Hyun Park, Jin-Woo Park
Pages: 281-285
Published online on: 01 March 2010

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Article

Inhibitory effects of cytoplasmic-domain substituted epidermal growth factor receptor on growth, invasion and angiogenesis in human gastric cancer cells

Gang Liao, Ziwei Wang, Lin Zhao, Neng Zhang, Pujiang Dong
Pages: 287-294
Published online on: 01 March 2010

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Article

Lentiviral-mediated Smad4 RNAi promotes SMMC-7721 cell migration by regulation of MMP-2, VEGF and MAPK signaling

Xiaodan Huang, Shu Huang, Faming Zhang, Xiang Han, Lin Miao, Zheng Liu, Zhining Fan, Guozhong Ji
Pages: 295-299
Published online on: 01 March 2010

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Article

Different threshold levels for 2-amino-3,8 dimethylimidazo[4,5-f]quinoxaline (MelQx) initiation of lung and colon carcinogenesis and the effects of an additional initiation by 4 (methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A/J mice

Satoshi Suzuki, Masanao Yokohira, Nozomi Hashimoto, Kousuke Saoo, Yoko Matsuda, Keiko Yamakawa, Yoko Nakano, Toshiya Kuno, Katsumi Imaida
Pages: 301-307
Published online on: 01 March 2010

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Article

Potentiation of the activity of cisplatin in a human colon tumour xenograft model by auristatin PYE, a structural modification of dolastatin 10

Ekatherine M. Prokopiou, Patricia A. Cooper, George R. Pettit, Michael C. Bibby, Steven D. Shnyder
Pages: 309-313
Published online on: 01 March 2010

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Article

Selective anticancer activity of β-lactams derived from polyaromatic compound

Bimal K. Banik, Frederick F. Becker
Pages: 315-316
Published online on: 01 March 2010

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Article

Chemoenzymatic preparation of intermediates for the taxol side chain and analogs

Bimal K. Banik, Mahima Negi, Maghar S. Manhas, Ajay K. Bose
Pages: 317-318
Published online on: 01 March 2010

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Article

Asymmetric synthesis of anticancer β-lactams via Staudinger reaction

Bimal K. Banik, Susanta Samajdar, Frederick F. Becker
Pages: 319-321
Published online on: 01 March 2010

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Article

Adiponectin suppresses inflammatory responses at the early phase of atherosclerosis in hyperglycemic rats

Jin-Bo Liu, Lin Jia, Bing-Rong Li, Li-Zhen Lan, Qian Ge, Hong-Ting Zhen, Hua-Cong Deng
Pages: 323-328
Published online on: 01 March 2010

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Article

Cysteinyl-leukotriene1 receptor antagonist prevents urological cancer cell growth through early apoptosis

Masahide Matsuyama, Kiyoaki Funao, Katsuyuki Kuratukuri, Tomoaki Tanaka, Yutaka Kawahito, Hajime Sano, Norio Yoshimura, Tatsuya Nakatani, Rikio Yoshimura
Pages: 329-332
Published online on: 01 March 2010

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Article

Combined effects of the proteasome inhibitor bortezomib and Hsp70 inhibitors on the B16F10 melanoma cell line

Azmi Yerlikaya, Emrah Okur, Semih Şeker, Nuray Erin
Pages: 333-339
Published online on: 01 March 2010

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Article

A novel putative interactor for the low density lipoprotein receptor cytoplasmic domain

Salvatore Costa, Aldo Nicosia, Maria A. Ragusa, Angelo B. Cefalù, Daniela Pollaccia, Davide Noto, Maurizio Averna, Fabrizio Gianguzza
Pages: 341-345
Published online on: 01 March 2010

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Article

Evaluation of insulin binding and signaling activity of newly synthesized chromium(III) complexes in vitro

Pawel Mackowiak, Zbigniew Krejpcio, Maciej Sassek, Przemyslaw Kaczmarek, Iwona Hertig, Joanna Chmielewska, Tatiana Wojciechowicz, Dawid Szczepankiewicz, Daria Wieczorek, Henryk Szymusiak, Krzysztof W. Nowak
Pages: 347-353
Published online on: 01 March 2010

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Article

CpG islands around exon 1 in the succinyl-CoA:3-ketoacid CoA transferase (SCOT) gene are hypomethylated even in human and mouse hepatic tissues where SCOT gene expression is completely suppressed

Toshiyuki Fukao, Gaixiu Zhang, Naoki Matsuo, Naomi Kondo
Pages: 355-359
Published online on: 01 March 2010

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Article

Type II cGMP-dependent protein kinase inhibits proliferation of the gastric cancer cell line BGC-823

Yong-Chang Chen, Feng Ren, Jian-Rong Sang, Yan Tao, Wen-Rong Xu
Pages: 361-366
Published online on: 01 March 2010

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Journal Cover
November-2026 Volume 34 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Research on the role and mechanism of SLC7A5 in idiopathic pulmonary fibrosis

Menghan Wang, Yao Yu, Zhaoyu Liu, Dandan Xu, Yupeng Li, Xing Zou, Ning Shan, Xining Liu, Ce Shi, Hong Chen
Article Number: 323
Published online on: 01 October 2026

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Review Open Access

Electroencephalography research in neuropathic pain (Review)

Lanling Zhou, Nianshun Liao, Hongmei Wang, Jiaxi Zhao, Haijun Jiang, Shihua Dang, Sixun Yu, Haifeng Shu, Xin Chen
Article Number: 322
Published online on: 25 September 2026

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BMAL1 in cardiovascular diseases: Molecular mechanisms, circadian regulation and translational perspectives (Review)

Yu Liang, Tingjin Chen, Xuemei Wen, Dan Liu, Zhongjian Zhang, Weiqing Li, Hengdi Zhang
Article Number: 321
Published online on: 24 September 2026

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Progress on quinoline‑based antitumour agents: Mechanistic insights and optimization strategies (Review)

Yuwen Zeng, Yutong Yan, Shiye Wu, Wanshan Wu, Ke Chen, Youyi Lai, Qing Ye, Nan Zhang, Yuanyuan Zhou
Article Number: 320
Published online on: 23 September 2026

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Review Open Access

Lactylation in gastric cancer: From mechanisms to clinical applications (Review)

Yuliang Fang, Peng Chen, Yuhong Gao, Yanpiao Li, Xue Li
Article Number: 319
Published online on: 23 September 2026

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Article Open Access

Sleep deprivation exacerbates lens‑induced myopia in association with ERK/NF‑κB pathway activation

Xueli Yang, Zhou Zhang, Chengbai Zhu, Jianbo Li, Wenting Gong, Ruirui Yang, Lipeng Guan
Article Number: 318
Published online on: 22 September 2026

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Review Open Access

Advances in biomarkers of benzene exposure and toxicity: From mechanistic insights to occupational health applications (Review)

Yuanshe Huang, Zhenjun Xi, Jingxin Mao, Xiaobing Li
Article Number: 317
Published online on: 21 September 2026

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Retraction Open Access

[Retracted] CALB1 enhances the interaction between p53 and MDM2, and inhibits the senescence of ovarian cancer cells

Long-Qiao Cao, Ya-Nan Wang, Ming Liang, Mei-Zhou Pan
Article Number: 316
Published online on: 21 September 2026

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Review Open Access

Artemisinin and its derivatives for metabolic syndrome: From multi‑target mechanisms to translational opportunities (Review)

Shuo Cao, Mo Yang, Siyu Qu, Jinsong Wu, Jiaheng Li, Ying Zhao
Article Number: 315
Published online on: 17 September 2026

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Article Open Access

Demethylase FTO attenuates atherosclerotic plaque via upregulating ABCA1 and ABCG1 expression by targeting ATG5

Fengxia Guo, Mei He, Yaonan Li, Kangning Zhu, Bing Hu
Article Number: 314
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Bcl11b regulates enamel matrix protein expression and dental epithelial cell differentiation during rat tooth development

Ziyue Li, Guoqing Chen, Yaling Yang, Weihua Guo, Weidong Tian
Article Number: 313
Published online on: 16 September 2026

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Review Open Access

Integrin αVβ3 as a context‑dependent regulator of bone homeostasis: Insights into osteoporosis pathogenesis and therapeutic targeting (Review)

Changshun Chen, Xingxi Hu, Sixing Wei, Yongcheng Deng, Qinggang Zhao, Ge Chen, Zhong Cheng, Jianhua Ji, Jinyi Gu
Article Number: 312
Published online on: 15 September 2026

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Article Open Access

Therapeutic effects of exosome‑based hyperin delivery in a cyclophosphamide‑induced mouse model of diminished ovarian reserve

Yi Ying, Yue Wu, Ji Zhou, Yaming Wang, Hongtao Yin, Gang Lu, Ruolang Pan, Liangzhong Lv
Article Number: 311
Published online on: 15 September 2026

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Arginine metabolism, polyamine homeostasis and ferroptosis in cancer: Molecular links and therapeutic opportunities (Review)

Xin Dong, Yongkun Hou, Jingjing Shao, Haixia Zhu, Jibin Liu
Article Number: 310
Published online on: 15 September 2026

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Review Open Access

Mitochondria‑associated endoplasmic reticulum membranes in degenerative musculoskeletal disorders: Mechanistic evidence and therapeutic perspectives (Review)

Shilong Meng, Xinlei Fu, Yawei Xu, Zhiliang Peng, Xu Zhang, Yanguang Cao, Binbin Tang, Xiaolin Shi, Kang Liu
Article Number: 309
Published online on: 15 September 2026

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Article Open Access

High‑fat diet exacerbates hepatic and adipose insulin signaling impairment and ovarian lesions in a rat model of letrozole‑induced polycystic ovary syndrome

Sunju So, Sujin Kwon, La Yoon Choi, Dae Yong Kim, Mi Hye Kim
Article Number: 308
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] RNAi‑mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non‑small lung cancer in vitro and in vivo

Liang Chang, Fangchao Gong, Youbin Cui
Article Number: 307
Published online on: 14 September 2026

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Article Open Access

A four‑gene signature identifies TKI‑induced persister cells and uncovers a ZLN005‑induced pyroptotic vulnerability via the GSDME pathway in EGFR‑mutant lung cancer

Wenwen Chang, Jiaxin Yuan, Huilin Zhang, Ying Yu, Yan Ma, Mingyue Li, Wenjing Li, Hongxia Yan, Chongran Sun, Peng Zhang, Yang Tian, Feng Guo, Pan Li, Yang Sun
Article Number: 306
Published online on: 11 September 2026

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Review Open Access

Research advances in the microbiota‑gut‑brain axis and Parkinson's disease (Review)

Yangping Meng, Qian Liu, Hao Zou, Xingyu Zhu, Xinxin Mi, Sitong Li, Yutian Xia, Yucheng Ma, Qianyu Yang, Jiaxin Peng, Junrui Li, Xingliang Liu, Junli Chen
Article Number: 305
Published online on: 10 September 2026

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Article Open Access

Ameliorative effects of Paulownia tomentosa flower absolute on atopic dermatitis‑related responses in mast cells and keratinocytes and its chemical composition

Da Yeon Yoo, Kyung Jong Won, Do Yoon Kim, Yoon Yi Kim, Ji Hye Bae, Ji Seong Yun, Hwan Myung Lee
Article Number: 304
Published online on: 10 September 2026

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Retraction Open Access

[Retracted] PYGB siRNA inhibits the cell proliferation of human osteosarcoma cell lines

Shuwei Zhang, Yichi Zhou, Yuanyu Zha, Yang Yang, Linlong Wang, Jingfeng Li, Wei Jin
Article Number: 303
Published online on: 10 September 2026

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Article Open Access

KIF4A drives esophageal squamous cell carcinoma via Wnt/β‑catenin signaling and predicts poor prognosis

Jialong Chen, Tong Wang, Da Wang, Weiguo Liu, Chunlai Liu, Yang Yang, Xiangfu Sun, Lei Zhou
Article Number: 302
Published online on: 08 September 2026

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Review Open Access

Research progress of aptamers in the diagnosis and treatment of colorectal cancer (Review)

Yiwen Li, Penghui Yan, Ji Zhang, Binghui Wu, Min Li, Baoliang Bao
Article Number: 301
Published online on: 08 September 2026

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Review Open Access

Role of the circadian rhythm in squamous cell carcinoma: From molecular mechanism to therapy (Review)

Mary-Lyn Eichhorn, Anna M. Dmitrieva, Lydia Meder
Article Number: 300
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ganoderma lucidum polysaccharide inhibits prostate cancer cell migration via the protein arginine methyltransferase 6 signaling pathway

Xiaohui Zhao, Dayu Zhou, Yunen Liu, Chun Li, Xiaoguang Zhao, Ying Li, Wei Li
Article Number: 299
Published online on: 07 September 2026

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Review Open Access

Multi‑omics approaches to decipher the molecular mechanisms of exercise‑mediated bone protection: From mechanistic insights to personalized exercise prescription (Review)

Bin Tian, Xuesong Chen, Xin Kang
Article Number: 298
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] MicroRNA‑27a promotes tumorigenesis via targeting AKT in triple negative breast cancer

Jing Wu, Zhihui Sun, Huijie Sun, Yanhua Li
Article Number: 297
Published online on: 03 September 2026

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Journal Cover
December-2026 Volume 34 Issue 6

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Piezo1 knockdown alleviates high‑altitude cerebral edema by improving brain microvascular endothelial cell tight junctions via blocking the calcium influx‑mediated Calpain‑1 activity

Taijian Cao, Zhicheng Xiang, Yangyang Zhao, Drolma Gomchok, Haifeng Ma, Shiwang Li, Dahai Cao, Chunqing Yang, Qiang Zhang
Article Number: 331
Published online on: 13 October 2026

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Navigating the landscape of targeted therapies for renal cell carcinoma in the era of precision medicine (Review)

Hongguo Cui, Jingheng Song, Peisen Yang, Zhengchao Zhang, Yuanyuan Liu, Gang Zhang, Aimin Tian, Jizhong Che, Yangyang Liu, Hui Sun, Yankai Xu
Article Number: 330
Published online on: 13 October 2026

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ΔNp63α‑mediated regulation of tumor‑associated genes and pathways in hepatocellular carcinoma progression

Xiaowen Lin, Anghui Peng, Min Zhang, Xinyang Yu
Article Number: 329
Published online on: 13 October 2026

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Article Open Access

 Leptin promotes obesity‑related osteoarthritis progression via CD44/JAK2/STAT3 axis‑mediated chondrocyte apoptosis

Hao Qiu, Chao Zeng, Cheng Chen, Xin Zhou, Yongjun Zhu, Zhongliang Deng
Article Number: 328
Published online on: 09 October 2026

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Review Open Access

Mechanical‑immune feedback regulation in distraction osteogenesis: From mechanotransduction to immune microenvironment remodeling (Review)

Xian Wang, Yuetong Wang, Shixi He, Cheng Ma, Zhengzhong He, Xuanping Huang
Article Number: 327
Published online on: 08 October 2026

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Review Open Access

Research progress in synergistic multimechanism of nanomaterial-mediated neuroinflammatory therapy (Review)

Heng Wang, Pei Yang, Wantao Liu
Article Number: 326
Published online on: 07 October 2026

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Retraction Open Access

[Retracted] (‑)‑Epicatechin protects against myocardial ischemia‑induced cardiac injury via activation of the PTEN/PI3K/AKT pathway

Jia-Wen Li, Xiao-Yun Wang, Xin Zhang, Lei Gao, Li-Feng Wang, Xin-Hua Yin
Article Number: 325
Published online on: 05 October 2026

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Review Open Access

Lactylation and exercise: A molecular link to disease alleviation (Review)

Jian Wang, Lei Wu
Article Number: 324
Published online on: 02 October 2026

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