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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2007 Volume 20 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Cultured rat calvarial osteoblast-like cells are provided with orexin type 1 receptors

Agnieszka Ziolkowska, Marcin Rucinski, Cinzia Tortorella, Marianna Tyczewska, Gastone G. Nussdorfer, Ludwik K. Malendowicz
Pages: 779-782
Published online on: 01 December 2007

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Evaluation of the peroxynitrite decomposition catalyst Fe(III) tetra-mesitylporphyrin octasulfonate on peripheral neuropathy in a mouse model of type 1 diabetes

Viktor R. Drel, Pal Pacher, Igor Vareniuk, Ivan A. Pavlov, Olga Ilnytska, Valeriy V. Lyzogubov, Seth R. Bell, John T. Groves, Irina G. Obrosova
Pages: 783-792
Published online on: 01 December 2007

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Article

Squamous cell carcinomas of the esophagus arise from a telomere-shortened epithelial field

Makoto Kammori, Steven S.S. Poon, Ken-Ichi Nakamura, Naotaka Izumiyama, Naoshi Ishikawa, Masahiko Kobayashi, Yoshio Naomoto, Kaiyo Takubo
Pages: 793-799
Published online on: 01 December 2007

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Article

Vitamin K2-induced cell growth inhibition via autophagy formation in cholangiocellular carcinoma cell lines

Masanobu Enomoto, Akihiko Tsuchida, Keisuke Miyazawa, Tomohisa Yokoyama, Hideaki Kawakita, Hiromi Tokita, Munekazu Naito, Masahiro Itoh, Kazuma Ohyashiki, Tatsuya Aoki
Pages: 801-808
Published online on: 01 December 2007

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Article

Six cases of citrin deficiency in Korea

Jung Min Ko, Gu-Hwan Kim, Ju-Hyun Kim, Jae Young Kim, Jin-Ho Choi, Miharu Ushikai, Takeyori Saheki, Keiko Kobayashi, Han-Wook Yoo
Pages: 809-815
Published online on: 01 December 2007

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Article

Effects of sivelestat sodium hydrate on the reduction of radiation pneumonitis

Taiju Shimbo, Taisuke Inomata, Masatsugu Takahashi, Toshiaki Tatsumi, Yasuo Uesugi, Isamu Narabayashi, Hiroshi Sonobe
Pages: 817-822
Published online on: 01 December 2007

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Article

Cathepsin B is involved in the apoptosis intrinsic pathway induced by Bacillus Calmette-Guérin in transitional cancer cell lines

Eduardo Sandes, Catalina Lodillinsky, Ruth Cwirenbaum, Claudia Argüelles, Alberto Casabé, Ana María Eiján
Pages: 823-828
Published online on: 01 December 2007

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Article

Microarray analysis of insulin-regulated gene expression in the liver: The use of transgenic mice co-expressing insulin-siRNA and human IDE as an animal model

Seungwan Jee, Daeyoun Hwang, Sujin Seo, Yongkyu Kim, Chuelkyu Kim, Byungguk Kim, Sunbo Shim, Suhae Lee, Jisoon Sin, Changjun Bae, Byoungchun Lee, Meekyung Jang, Minsun Kim, Suyoun Yim, Insurk Jang, Jungsik Cho, Kabryong Chae
Pages: 829-835
Published online on: 01 December 2007

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Review

Endogenous morphine synthetic pathway preceded and gave rise to catecholamine synthesis in evolution (Review)

George B. Stefano, Richard M. Kream
Pages: 837-841
Published online on: 01 December 2007

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Article

Radical scavenging activity of ‘Nikogori’ gelatin gel food made from head, bone, skin, tail and scales of fishes measured using the chemiluminescence method

Norie Nagatsuka, Kumi Sato, Kazuki Harada, Keiko Nagao
Pages: 843-847
Published online on: 01 December 2007

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Association between promoter polymorphisms of nuclear factor-erythroid 2-related factor 2 gene and peptic ulcer diseases

Tomiyasu Arisawa, Tomomitsu Tahara, Tomoyuki Shibata, Mitsuo Nagasaka, Masakatsu Nakamura, Yoshio Kamiya, Hiroshi Fujita, Daisuke Yoshioka, Yuko Arima, Masaaki Okubo, Ichiro Hirata, Hiroshi Nakano
Pages: 849-853
Published online on: 01 December 2007

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Article

Up-regulation of adrenomedullin receptor gene expression in activated local stem cells during rat adrenal regeneration

Piera Rebuffat, Carlo Macchi, Ludwik K. Malendowicz, Gastone G. Nussdorfer
Pages: 855-858
Published online on: 01 December 2007

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Article

Galanin stimulates cortisol secretion from human adrenocortical cells through the activation of galanin receptor subtype 1 coupled to the adenylate cyclase-dependent signaling cascade

Anna S. Belloni, Ludwik K. Malendowicz, Marcin Rucinski, Diego Guidolin, Gastone G. Nussdorfer
Pages: 859-864
Published online on: 01 December 2007

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Article

Heart protein expression related to age and sex in mice and humans

Madeleine Diedrich, Jadranka Tadic, Lei Mao, Maik A. Wacker, Grit Nebrich, Roland Hetzer, Vera Regitz-Zagrosek, Joachim Klose
Pages: 865-874
Published online on: 01 December 2007

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Article

Human drug metabolism genes in parathion-and estrogen-treated breast cells

G. M. Calaf, D. Roy
Pages: 875-881
Published online on: 01 December 2007

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Article

Increased cytokine secretion in head and neck cancer upon p38 mitogen-activated protein kinase activation

Christine Riebe, Ralph Pries, Andrea Kemkers, Barbara Wollenberg
Pages: 883-887
Published online on: 01 December 2007

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Article

Stimulation of collagen biosynthesis by flavonoid glycosides in skin fibroblasts of osteogenesis imperfecta type I and the potential mechanism of their action

Anna Galicka, Jolanta Nazaruk
Pages: 889-895
Published online on: 01 December 2007

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Article

Perturbation and age-related changes in the fatty acid pattern of soleus muscle phospholipids and triglycerides in rats depleted in long-chain polyunsaturated ω3 fatty acids

Willy J. Malaisse, Laurence Portois, Abdullah Sener, Yvon A. Carpentier
Pages: 897-904
Published online on: 01 December 2007

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Article

Entropy-based analysis of the non-linear relationship between gene expression profiles of amplified and non-amplified RNA

Ji Hye Shin, Chan Ho Park, Yeon Ju Yang, Sang Chul Kim, Min Young Seo, Sang Hwa Yang, Sung Bae Cho, Hyun Cheol Chung, Sun Young Rha
Pages: 905-912
Published online on: 01 December 2007

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Article

Phospholipase A as a potent virulence factor of Vibrio vulnificus

Bon-Sun Koo, Ji-Hyun Lee, Soon-Cheol Kim, Ha-Yong Yoon, Kyung-Ah Kim, Kang-Beom Kwon, Hyung-Rho Kim, Jin-Woo Park, Byung-Hyun Park
Pages: 913-918
Published online on: 01 December 2007

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Article

Evaluation of copper-dependent proteasome-inhibitory and apoptosis-inducing activities of novel pyrrolidine dithiocarbamate analogues

Zhiyong Yu, Fei Wang, Vesna Milacic, Xiaofeng Li, Qiuzhi Cindy Cui, Bin Zhang, Bing Yan, Q. Ping Dou
Pages: 919-925
Published online on: 01 December 2007

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

miR‑205: A dual regulator of angiogenesis in health and disease (Review)

Maria Oltra, Miriam Martínez‑Santos, Maria Ybarra, Maria Pires, Chiara Ceresoni, Clara Gomis‑Coloma, Cristina Medina‑Trillo, Javier Sancho, Jorge Barcia
Article Number: 51
Published online on: 29 December 2025

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Astragaloside IV: A multipotent phytochemical for treating fibrotic diseases (Review)

Mingyu Wu, Ke Li, Jiabin Wu, Qiuyu Zhang, Xiaotong Ma, Wei Dai, Haoyang Gao, Xianyi Ding, Wenhong Wang, Weihua Xiao
Article Number: 50
Published online on: 24 December 2025

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Activating transcription factors: Orchestrators of macrophage biology in pathological settings (Review)

Yue-Chen Liu, Jia-Wei Zhao, Xiong-Tao Yue, Qi-Jie Chen, Shan-Jie Rong, Shi-Wei Liu, Fei Sun, Chun-Liang Yang, Cong-Yi Wang
Article Number: 49
Published online on: 24 December 2025

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Role of SIRT3 in digestive system diseases and therapeutic prospects (Review)

Jiajia Li, Qian Liu, Shun Yao, Xin Li, Li Zhang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 48
Published online on: 22 December 2025

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Recombinant ADAMTS‑1 promotes muscle regeneration accompanied by downregulation of Notch signaling

Jin-Hwa Kim, Sang-Hyup Lee, Sang-Yoon Kim, Jeong-Won Kim, Ji-Soo Jeong, Eun-Hye Chung, Su-Ha Lee, Chang-Yeop Kim, Bong-Keun Choi, Je-Won Ko, Tae-Won Kim
Article Number: 47
Published online on: 22 December 2025

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A comprehensive review on pain: Model, target, therapy, and prospect (Review)

Chenyu Chang, Xutao Wu, Kejia Liu, Lei Wang, Mozili Adu, Qingyuan Lin, Huilian Huang, Qinge Ma, Rongrui Wei, Xiaoyun Wang, Wenmin Liu
Article Number: 46
Published online on: 17 December 2025

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[Retracted] Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore

Yanbing Zhao, Yuxuan Guo, Yuqiong Chen, Shuang Liu, Nan Wu, Dalin Jia
Article Number: 45
Published online on: 15 December 2025

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Nanomaterials and exercise interventions: A synergistic approach for atherosclerosis therapy (Review)

Quanquan Zhou, Ge‑Lin Zhang, Weitong Sun, Jiayi Cai, Li-Hua Yu
Article Number: 44
Published online on: 10 December 2025

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Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease

Yiyang Pan, Feng Yang, Liucan Wang, Tianshu Yang, Guangsheng Du, Cong Xu, Hua Yang, Min Yu, Weidong Xiao
Article Number: 43
Published online on: 10 December 2025

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Lactylation‑mediated ferroptosis: A novel mechanism and therapeutic prospects in human diseases (Review)

Zhengjun Lin, Yugang Zou, Songzhu Zou, Kunming Wen
Article Number: 42
Published online on: 08 December 2025

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Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)

Qian Yu, Yu Kuang, Jie He, Li Yang, Xinjie Li, Hao Yu
Article Number: 41
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑493‑5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP2

Guannan Wang, Xiaosan Fang, Meng Han, Xiaoming Wang, Qiang Huang
Article Number: 40
Published online on: 08 December 2025

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Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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