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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
Feb 1998 Volume 12 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

The predictive role of flow cytometry-derived tumor potential doubling time (Tpot) in radiotherapy: open questions and future perspectives.

P Antognoni, NHA Terry NHA, A Richetti, R Luraghi, M Tordiglione, M Danova
Pages: 245-301
Published online on: 01 February 1998

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Article

Establishment and characterization of immortalized human cell lines from prostatic carcinoma and benign prostatic hyperplasia.

P T Iype, L E Iype, M Verma, M E Kaighn
Pages: 257-320
Published online on: 01 February 1998

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Article

Irradiation with ultraviolet light and gamma-rays increases the level of DNA topoisomerase II in nuclei of normal and xeroderma pigmentosum fibroblasts.

H W Thielmann, O Popanda
Pages: 265-336
Published online on: 01 February 1998

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Article

Mitogenic signaling by substance P and bombesin-like neuropeptide receptors in astrocytic/glial brain tumor-derived cell lines.

M Sharif
Pages: 273-359
Published online on: 01 February 1998

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Article

Multidrug resistance mediated by overexpression of P-glycoprotein in human osteosarcoma in vivo.

R Suto, Y Abe, M Nakamura, Y Ohnishi, M Yoshimura, Y H Lee, T Imanishi, H Yamazaki, H Kijima, T Tokunaga, Y Oshika, N Hiraoka, N Tamaoki, H Fukuda, Y Ueyama
Pages: 287-378
Published online on: 01 February 1998

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Article

Reduced expression of E-cadherin in oral squamous cell carcinoma: relationship with DNA methylation of 5' CpG island.

Y Saito, H Takazawa, K Uzawa, H Tanzawa, K Sato
Pages: 293-301
Published online on: 01 February 1998

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Article

Role of p53 and apoptosis in sensitization of cis-diamminedichloroplatinum antitumor activity by interleukin-1 in ovarian carcinoma cells.

K Song, P Fukushima, P Seth, B K Sinha
Pages: 299-603
Published online on: 01 February 1998

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Article

Evidence that breast cancer associated microcalcifications are mineralized malignant cells.

V Castronovo, A Bellahcene
Pages: 305-313
Published online on: 01 February 1998

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Article

Expression of human endogenous retrovirus ERV3 (HERV-R) mRNA in normal and neoplastic tissues.

A C Andersson, A C Svensson, C Rolny, G Andersson, E Larsson
Pages: 309-322
Published online on: 01 February 1998

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Article

Differential expression and activity of P-glycoprotein and multidrug resistance-associated protein in CD34-positive KG1a leukemic cells.

O Fardel, L Payen, A Courtois, B Drenou, R Fauchet, B Rault
Pages: 315-324
Published online on: 01 February 1998

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Article

Induction of antitumor effect on human esophageal carcinoma cells by the retroviral expression of granulocyte macrophage-colony stimulating factor gene.

M Sugaya, M Tagawa, H Matsubara, Y Gunji, K Takenaga, T Maeda, Y Koide, T Asano, T Ochiai, K Isono, S Sakiyama
Pages: 321-325
Published online on: 01 February 1998

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Article

p53-independent down-regulation of cyclin D1 and p21Waf1 in the process of immortalization of human esophageal epithelial cells.

H Wang, E A Spillare, Q S Wang, CLK Sabourin CLK, GD Stoner
Pages: 325-333
Published online on: 01 February 1998

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Article

Epidermal growth factor receptor and insulin-like growth factor-I receptor expression and function in human soft-tissue sarcoma cells.

D Beech, R E Pollock, R Tsan, R Radinsky
Pages: 329-365
Published online on: 01 February 1998

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Article

Surface plasmon resonance for real-time monitoring of molecular interactions between a triple helix forming oligonucleotide and the Sp1 binding sites of human Ha-ras promoter: effects of the DNA-binding drug chromomycin.

C Rutigliano, N Bianchi, M Tomassetti, L Pippo, C Mischiati, G Feriotto, R Gambari
Pages: 337-380
Published online on: 01 February 1998

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Article

Analysis of cell kinetics after gamma-ray irradiation using an anti-BrdU monoclonal antibody.

T Murata, K Akagi, R Nasu, H Kimura, Y Tanaka
Pages: 345-354
Published online on: 01 February 1998

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Article

Spontaneous apoptosis in ovarian cancer: an unfavorable prognostic factor.

J Mattern, G Stammler, R Koomagi, D Wallwiener, M Kaufmann, M Volm
Pages: 351-355
Published online on: 01 February 1998

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Article

Retinoic acid suppresses insulin-induced cell growth and cyclin D1 gene expression in human breast cancer cells.

S Bardon, L Razanamahefa
Pages: 355-364
Published online on: 01 February 1998

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Article

Expression of Tn antigen and N-acetyllactosamine residues in malignant and benign human breast tumors detected by lectins and monoclonal antibody 83D4.

G Konska, J Guillot, M De Latour, Y Fonck
Pages: 361-368
Published online on: 01 February 1998

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Article

Altered expression of c-erbB-2, DF3, b72.3, p53 and Ki-67 with progression and differentiation to two distinct histologic types of invasive carcinoma in the MCF10AT human xenograft model of proliferative breast disease.

S Iravani, L Mora, F R Miller, P J Dawson
Pages: 369-444
Published online on: 01 February 1998

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Article

DNA synthesis, mismatch repair and cancer.

J S Hoffmann, C Cazaux
Pages: 377-459
Published online on: 01 February 1998

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Article

Regulation of the MDR1 promoter by cyclic AMP-dependent protein kinase and transcription factor Sp1.

C Rohlff, R I Glazer
Pages: 383-389
Published online on: 01 February 1998

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Article

Immunogenicity, immunosensitivity and cell surface adhesiveness of tumour vaccines carrying an inserted CD80 gene.

M Indrova, J Bubenik, P Rossner, J Zeuthen, T Jandlova, V Sobota
Pages: 387-477
Published online on: 01 February 1998

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Article

New active paclitaxel glucuronide derivative with improved water solubility.

R Paradis, M Page
Pages: 391-395
Published online on: 01 February 1998

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Article

Detection of numerical chromosomal changes in 20 malignant fibrous histiocytomas by FISH.

H Schmidt, S Korber, R Hinze, H Taubert, A Meye, P Wurl, M Bache, H J Holzhausen, H Dralle, F W Rath
Pages: 395-797
Published online on: 01 February 1998

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Article

Alterations in differentiation and apoptosis induced by bufalin in cJun overexpressing U-937 cells.

E Szabo, J Francis, M J Birrer
Pages: 403-412
Published online on: 01 February 1998

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Article

Characterization of CCK-B/gastrin-like receptors in human gastric carcinoma.

J P Smith, A H Shih, M G Wotring, P J McLaughlin, I S Zagon
Pages: 411-420
Published online on: 01 February 1998

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Article

Clinicopathologic study of multiple primary superficial carcinoma of the esophagus.

T Fujii, H Yamana, H Fujita, S Sueyoshi, A Nakashima, I Hayashi, M Nishi, S Kato, K Shirouzu, M Morimatsu
Pages: 421-426
Published online on: 01 February 1998

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Article

Suppression of uterine insulin-like growth factor binding protein 5 by estrogen is mediated in part by insulin-like growth factor I.

H Huynh
Pages: 427-459
Published online on: 01 February 1998

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Article

Tricyclic pyrone analogs: a new class of microtubule-disrupting anticancer drugs effective against murine leukemia cells in vitro.

S W Newell, E M Perchellet, J B Ladesich, J A Freeman, Y Chen, L Liu, D H Hua, S L Kraft, R J Basaraba, J P Perchellet
Pages: 433-475
Published online on: 01 February 1998

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Article

Immunoexpression of E-cadherin and beta-catenin correlates to survival of patients with hepatocellular carcinomas.

S Garcia, F Martini, C De Micco, L Andrac, J Hardwigsen, P Sappa, M N Lavaut, Y P Le Treut, C Charpin
Pages: 443-450
Published online on: 01 February 1998

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Article

Genetic alterations in the development of mammary and prostate cancer in the C3(1)/Tag transgenic mouse model.

K Yoshidome, M A Shibata, I G Maroulakou, M L Liu, C L Jorcyk, L G Gold, V N Welch, J E Green
Pages: 449-502
Published online on: 01 February 1998

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Article

p53 overexpression in small hepatocellular carcinomas containing two different histologic grades.

Y Nakashima, C C Hsia, H Yuwen, M Minemura, O Nakashima, M Kojiro, E Tabor
Pages: 455-464
Published online on: 01 February 1998

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Article

In vivo single voxel 1H MRS of glial brain tumors: correlation with tissue histology and in vitro MRS.

G Barbarella, R Ricci, G Pirini, V Tugnoli, M R Tosi, A Bertoluzza, F Calbucci, M Leonardi, C Trevisan, V Eusebi
Pages: 461-469
Published online on: 01 February 1998

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Article

p53 modulation of Fas/Apo-1 mediated apoptosis in a human renal cell carcinoma cell line.

H Miyake, I Hara, K Gohji, S Arakawa, S Kamidono
Pages: 469-542
Published online on: 01 February 1998

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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Review Open Access

IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Review

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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Article Open Access

lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Review Open Access

Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Review Open Access

Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Review Open Access

Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Review Open Access

Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Review Open Access

Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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Journal Cover
May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Smoking promotes colorectal cancer via the CKAP2L/AREG axis

Shasha Wu, Feixiang Wu, Xiaoqing Li, Zhihang Jiang, Fuqiang Liu, Zheng Jiang
Article Number: 59
Published online on: 13 March 2026

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Article Open Access

Diverse roles of SERPINE1 in regulating cellular proliferation and invasion

Wei Wang, Pengfei Zhao, Tian Wang, Weijing Wu, Jing Li, Qiang Huang, Jing Momo
Article Number: 58
Published online on: 13 March 2026

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Article Open Access

Therapeutic implications of targeting cancer testis antigen MAGEA1 in cervical cancer

Ayoung Kim, Jina Kim, Woori Kwak, Kyumin Mo, Soohyun Choe, Minyeong Jeon, Jisun Lee, Jun-Won Yun, Hyunho Yoon
Article Number: 57
Published online on: 12 March 2026

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Review Open Access

Enolase 1: A paradigm of metabolic enzyme moonlighting in tumorigenesis (Review)

Xiaochen Ni, Mingsi Zhang, Kaiyuan Zhang, Chuhang Wang, Jianing Guo, Wei Fan, Linfeng Zheng, Tao Jiang, Guangji Zhang
Article Number: 56
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Article Number: 55
Published online on: 09 March 2026

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Review Open Access

Pancreatic cancer EMT‑targeted therapy: Molecular mechanisms and clinical translation (Review)

Guirui Zhang, Yongmo Wu, Mingzhen Wei, Shupeng Huang, Qinghao Wang, Zhengyi Xie, Sisi Liu, Jin Wang
Article Number: 54
Published online on: 06 March 2026

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Retraction Open Access

[Retracted] Design, synthesis and preclinical evaluation of NRC‑AN‑019

Kompella Amala, A.K.S. Bhujanga Rao, Bharathi Gorantla, Christopher S.  Gondi, Jasti S. Rao
Article Number: 53
Published online on: 04 March 2026

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Article Open Access

FOXM1 inhibitor, RCM‑1, enhances venetoclax mediated apoptosis through downregulation of ATP2B4 in rhabdomyosarcoma

Nawal Merjaneh, Ying-Wei Lan, Zicheng Deng, Johnny Donovan, Guolun Wang, Jonathan Do, Tiffany Juan, Xiaomei Xia, Vladimir V. Kalinichenko, Tanya V. Kalin
Article Number: 52
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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Article Open Access

RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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