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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
Feb 1998 Volume 12 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

The predictive role of flow cytometry-derived tumor potential doubling time (Tpot) in radiotherapy: open questions and future perspectives.

P Antognoni, NHA Terry NHA, A Richetti, R Luraghi, M Tordiglione, M Danova
Pages: 245-301
Published online on: 01 February 1998

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Article

Establishment and characterization of immortalized human cell lines from prostatic carcinoma and benign prostatic hyperplasia.

P T Iype, L E Iype, M Verma, M E Kaighn
Pages: 257-320
Published online on: 01 February 1998

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Article

Irradiation with ultraviolet light and gamma-rays increases the level of DNA topoisomerase II in nuclei of normal and xeroderma pigmentosum fibroblasts.

H W Thielmann, O Popanda
Pages: 265-336
Published online on: 01 February 1998

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Article

Mitogenic signaling by substance P and bombesin-like neuropeptide receptors in astrocytic/glial brain tumor-derived cell lines.

M Sharif
Pages: 273-359
Published online on: 01 February 1998

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Article

Multidrug resistance mediated by overexpression of P-glycoprotein in human osteosarcoma in vivo.

R Suto, Y Abe, M Nakamura, Y Ohnishi, M Yoshimura, Y H Lee, T Imanishi, H Yamazaki, H Kijima, T Tokunaga, Y Oshika, N Hiraoka, N Tamaoki, H Fukuda, Y Ueyama
Pages: 287-378
Published online on: 01 February 1998

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Article

Reduced expression of E-cadherin in oral squamous cell carcinoma: relationship with DNA methylation of 5' CpG island.

Y Saito, H Takazawa, K Uzawa, H Tanzawa, K Sato
Pages: 293-301
Published online on: 01 February 1998

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Article

Role of p53 and apoptosis in sensitization of cis-diamminedichloroplatinum antitumor activity by interleukin-1 in ovarian carcinoma cells.

K Song, P Fukushima, P Seth, B K Sinha
Pages: 299-603
Published online on: 01 February 1998

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Article

Evidence that breast cancer associated microcalcifications are mineralized malignant cells.

V Castronovo, A Bellahcene
Pages: 305-313
Published online on: 01 February 1998

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Article

Expression of human endogenous retrovirus ERV3 (HERV-R) mRNA in normal and neoplastic tissues.

A C Andersson, A C Svensson, C Rolny, G Andersson, E Larsson
Pages: 309-322
Published online on: 01 February 1998

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Article

Differential expression and activity of P-glycoprotein and multidrug resistance-associated protein in CD34-positive KG1a leukemic cells.

O Fardel, L Payen, A Courtois, B Drenou, R Fauchet, B Rault
Pages: 315-324
Published online on: 01 February 1998

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Article

Induction of antitumor effect on human esophageal carcinoma cells by the retroviral expression of granulocyte macrophage-colony stimulating factor gene.

M Sugaya, M Tagawa, H Matsubara, Y Gunji, K Takenaga, T Maeda, Y Koide, T Asano, T Ochiai, K Isono, S Sakiyama
Pages: 321-325
Published online on: 01 February 1998

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Article

p53-independent down-regulation of cyclin D1 and p21Waf1 in the process of immortalization of human esophageal epithelial cells.

H Wang, E A Spillare, Q S Wang, CLK Sabourin CLK, GD Stoner
Pages: 325-333
Published online on: 01 February 1998

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Article

Epidermal growth factor receptor and insulin-like growth factor-I receptor expression and function in human soft-tissue sarcoma cells.

D Beech, R E Pollock, R Tsan, R Radinsky
Pages: 329-365
Published online on: 01 February 1998

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Article

Surface plasmon resonance for real-time monitoring of molecular interactions between a triple helix forming oligonucleotide and the Sp1 binding sites of human Ha-ras promoter: effects of the DNA-binding drug chromomycin.

C Rutigliano, N Bianchi, M Tomassetti, L Pippo, C Mischiati, G Feriotto, R Gambari
Pages: 337-380
Published online on: 01 February 1998

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Article

Analysis of cell kinetics after gamma-ray irradiation using an anti-BrdU monoclonal antibody.

T Murata, K Akagi, R Nasu, H Kimura, Y Tanaka
Pages: 345-354
Published online on: 01 February 1998

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Article

Spontaneous apoptosis in ovarian cancer: an unfavorable prognostic factor.

J Mattern, G Stammler, R Koomagi, D Wallwiener, M Kaufmann, M Volm
Pages: 351-355
Published online on: 01 February 1998

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Article

Retinoic acid suppresses insulin-induced cell growth and cyclin D1 gene expression in human breast cancer cells.

S Bardon, L Razanamahefa
Pages: 355-364
Published online on: 01 February 1998

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Article

Expression of Tn antigen and N-acetyllactosamine residues in malignant and benign human breast tumors detected by lectins and monoclonal antibody 83D4.

G Konska, J Guillot, M De Latour, Y Fonck
Pages: 361-368
Published online on: 01 February 1998

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Article

Altered expression of c-erbB-2, DF3, b72.3, p53 and Ki-67 with progression and differentiation to two distinct histologic types of invasive carcinoma in the MCF10AT human xenograft model of proliferative breast disease.

S Iravani, L Mora, F R Miller, P J Dawson
Pages: 369-444
Published online on: 01 February 1998

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Article

DNA synthesis, mismatch repair and cancer.

J S Hoffmann, C Cazaux
Pages: 377-459
Published online on: 01 February 1998

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Article

Regulation of the MDR1 promoter by cyclic AMP-dependent protein kinase and transcription factor Sp1.

C Rohlff, R I Glazer
Pages: 383-389
Published online on: 01 February 1998

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Article

Immunogenicity, immunosensitivity and cell surface adhesiveness of tumour vaccines carrying an inserted CD80 gene.

M Indrova, J Bubenik, P Rossner, J Zeuthen, T Jandlova, V Sobota
Pages: 387-477
Published online on: 01 February 1998

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Article

New active paclitaxel glucuronide derivative with improved water solubility.

R Paradis, M Page
Pages: 391-395
Published online on: 01 February 1998

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Article

Detection of numerical chromosomal changes in 20 malignant fibrous histiocytomas by FISH.

H Schmidt, S Korber, R Hinze, H Taubert, A Meye, P Wurl, M Bache, H J Holzhausen, H Dralle, F W Rath
Pages: 395-797
Published online on: 01 February 1998

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Article

Alterations in differentiation and apoptosis induced by bufalin in cJun overexpressing U-937 cells.

E Szabo, J Francis, M J Birrer
Pages: 403-412
Published online on: 01 February 1998

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Article

Characterization of CCK-B/gastrin-like receptors in human gastric carcinoma.

J P Smith, A H Shih, M G Wotring, P J McLaughlin, I S Zagon
Pages: 411-420
Published online on: 01 February 1998

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Article

Clinicopathologic study of multiple primary superficial carcinoma of the esophagus.

T Fujii, H Yamana, H Fujita, S Sueyoshi, A Nakashima, I Hayashi, M Nishi, S Kato, K Shirouzu, M Morimatsu
Pages: 421-426
Published online on: 01 February 1998

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Article

Suppression of uterine insulin-like growth factor binding protein 5 by estrogen is mediated in part by insulin-like growth factor I.

H Huynh
Pages: 427-459
Published online on: 01 February 1998

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Article

Tricyclic pyrone analogs: a new class of microtubule-disrupting anticancer drugs effective against murine leukemia cells in vitro.

S W Newell, E M Perchellet, J B Ladesich, J A Freeman, Y Chen, L Liu, D H Hua, S L Kraft, R J Basaraba, J P Perchellet
Pages: 433-475
Published online on: 01 February 1998

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Article

Immunoexpression of E-cadherin and beta-catenin correlates to survival of patients with hepatocellular carcinomas.

S Garcia, F Martini, C De Micco, L Andrac, J Hardwigsen, P Sappa, M N Lavaut, Y P Le Treut, C Charpin
Pages: 443-450
Published online on: 01 February 1998

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Article

Genetic alterations in the development of mammary and prostate cancer in the C3(1)/Tag transgenic mouse model.

K Yoshidome, M A Shibata, I G Maroulakou, M L Liu, C L Jorcyk, L G Gold, V N Welch, J E Green
Pages: 449-502
Published online on: 01 February 1998

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Article

p53 overexpression in small hepatocellular carcinomas containing two different histologic grades.

Y Nakashima, C C Hsia, H Yuwen, M Minemura, O Nakashima, M Kojiro, E Tabor
Pages: 455-464
Published online on: 01 February 1998

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Article

In vivo single voxel 1H MRS of glial brain tumors: correlation with tissue histology and in vitro MRS.

G Barbarella, R Ricci, G Pirini, V Tugnoli, M R Tosi, A Bertoluzza, F Calbucci, M Leonardi, C Trevisan, V Eusebi
Pages: 461-469
Published online on: 01 February 1998

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Article

p53 modulation of Fas/Apo-1 mediated apoptosis in a human renal cell carcinoma cell line.

H Miyake, I Hara, K Gohji, S Arakawa, S Kamidono
Pages: 469-542
Published online on: 01 February 1998

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Expression of Concern Open Access

[Expression of Concern] Establishment and evaluation of a new highly metastatic tumor cell line 5a‑D‑Luc‑ZsGreen expressing both luciferase and green fluorescent protein

Hitomi Sudo, Atsushi B. Tsuji, Aya Sugyo, Hiroyuki Takuwa, Kazuto Masamoto, Yutaka Tomita, Norihiro Suzuki, Takeshi Imamura, Mitsuru Koizumi, Tsuneo Saga
Article Number: 27
Published online on: 17 December 2025

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Review Open Access

Exosomal circRNAs in hepatocellular carcinoma: Implications for the development and therapeutic resistance of hepatocellular carcinoma (Review)

Zhiyao Liu, Yuqiao Wang, Yali Wang, Yucheng Zhang
Article Number: 26
Published online on: 16 December 2025

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Review Open Access

Advancements on the synergistic application of oncolytic viruses and molecularly targeted therapies for the treatment of solid tumors (Review)

Shiwen Bi, Tiyan Shan, Yong Tang, Qi Wang
Article Number: 25
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] Epigenetic high regulation of ATAD2 regulates the Hh pathway in human hepatocellular carcinoma

Gang Wu, Xiaojun Lu, Yawei Wang, Hui He, Xiangyu Meng, Shuguan Xia, Kunming Zhen, Yongfeng Liu
Article Number: 24
Published online on: 16 December 2025

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Review

CCDC137: A key hub for RNA and epigenetic regulation in cancer research (Review)

Xiaoying Zhao, Wenjing Zhang, Xiang Yu, Xiaohan Zhao, Xu Dai, Sirui Chen, Yan Wang, Jiang Cheng, Weiwei Zheng
Article Number: 23
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] Characterization of side population cells isolated from the colon cancer cell line SW480

Binghong Xiong, Li Ma, Xiang Hu, Caiquan Zhang, Yong Cheng
Article Number: 22
Published online on: 10 December 2025

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Review Open Access

mTOR in radiotherapy of lung cancer: Mechanisms of radiation resistance and therapeutic implications (Review)

Xiao Pang, Huai Liu, Ying Long, Hui Wang
Article Number: 21
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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