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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2012 Volume 41 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Circulating microRNAs: New biomarkers in diagnosis, prognosis and treatment of cancer (Review)

Alessandro Allegra, Andrea Alonci, Salvatore Campo, Giuseppa Penna, Annamaria Petrungaro, Demetrio Gerace, Caterina Musolino
Pages: 1897-1912
Published online on: 01 October 2012

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Article Open Access

Function and cancer genomics of FAT family genes (Review)

Masaru Katoh
Pages: 1913-1918
Published online on: 17 October 2012

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Review

The insulin-like growth factor (IGF) signaling axis and hepatitis C virus-associated carcinogenesis (Review)

Aldona Kasprzak, Agnieszka Adamek
Pages: 1919-1931
Published online on: 16 October 2012

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Article Open Access

Established breast cancer stem cell markers do not correlate with in vivo tumorigenicity of tumor-initiating cells

Christian Lehmann, Gabriele Jobs, Markus Thomas, Helmut Burtscher, Manfred Kubbies
Pages: 1932-1942
Published online on: 05 October 2012

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Article Open Access

Ciprofloxacin is a potential topoisomerase II inhibitor for the treatment of NSCLC

Tomasz Kloskowski, Natalia Gurtowska, Joanna Olkowska, Jakub Marcin Nowak, Jan  Adamowicz, Jakub Tworkiewicz, Robert Dębski, Alina Grzanka, Tomasz Drewa
Pages: 1943-1949
Published online on: 04 October 2012

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Article Open Access

Topographic and quantitative relationship between prostate inflammation, proliferative inflammatory atrophy and low-grade prostate intraepithelial neoplasia: A biopsy study in chronic prostatitis patients

A. Vral, V. Magri, E. Montanari, G. Gazzano, V. Gourvas, E. Marras, G. Perletti
Pages: 1950-1958
Published online on: 01 October 2012

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Article Open Access

Cell type and context-specific function of PLAG1 for IGF2 P3 promoter activity

Monira Akhtar, Claes Holmgren, Anita Göndör, Mattias Vesterlund, Chandrasekhar Kanduri, Catharina Larsson, Tomas J. Ekström
Pages: 1959-1966
Published online on: 26 September 2012

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Article Open Access

Downregulation of protein kinase CK2 induces autophagic cell death through modulation of the mTOR and MAPK signaling pathways in human glioblastoma cells

Birgitte B. Olsen, Tina H. Svenstrup, Barbara Guerra
Pages: 1967-1976
Published online on: 21 September 2012

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Article Open Access

MUC1 glycopeptide epitopes predicted by computational glycomics

Wei Song, Elizabeth S. Delyria, Jieqing Chen, Wei Huang, Jun Soo Lee, Elizabeth A. Mittendorf, Nuhad Ibrahim, Laszlo G. Radvanyi, Yunsen Li, Hongzhou Lu, Huaxi Xu, Yinqiang Shi, Lai-Xi Wang, Jeremy A. Ross, Silas P. Rodrigues, Igor C. Almeida, Xifeng Yang, Jin Qu, Nathaniel S. Schocker, Katja Michael, Dapeng Zhou
Pages: 1977-1984
Published online on: 27 September 2012

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Article Open Access

T-box transcription factor Brachyury expression is correlated with epithelial-mesenchymal transition and lymph node metastasis in oral squamous cell carcinoma

Ikumi Imajyo, Tsuyoshi Sugiura, Yosuke Kobayashi, Miyuki Shimoda, Kotaro Ishii, Naonari Akimoto, Naoya Yoshihama, Ieyoshi Kobayashi, Yoshihide Mori
Pages: 1985-1995
Published online on: 17 October 2012

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Article Open Access

In vitro and in vivo inhibition of human Fanconi anemia-associated head and neck squamous cell carcinoma by a novel nutrient mixture

M. W. Roomi, T. Kalinovsky, N. W. Roomi, A. Niedzwiecki, M. Rath
Pages: 1996-2004
Published online on: 24 September 2012

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Article

Hypoxia downregulates the expression of cell surface MICA without increasing soluble MICA in osteosarcoma cells in a HIF-1α-dependent manner

Naoko Yamada, Koji Yamanegi, Hideki Ohyama, Masaki Hata, Keiji Nakasho, Hiroyuki Futani, Haruki Okamura, Nobuyuki Terada
Pages: 2005-2012
Published online on: 18 September 2012

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Article

Genomic copy number alterations associated with the early brain metastasis of non-small cell lung cancer

Hye Won Lee, Ho Jun Seol, Yoon-La Choi, Hyun Jung Ju, Kyeung Min Joo, Young-Hyeh Ko, Jung-Il Lee, Do-Hyun Nam
Pages: 2013-2020
Published online on: 15 October 2012

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Article Open Access

CD82 inhibits canonical Wnt signalling by controlling the cellular distribution of β-catenin in carcinoma cells

Satomi Chigita, Tsuyoshi Sugiura, Masakazu Abe, Yosuke Kobayashi, Miyuki Shimoda, Megumi Onoda, Kanemitsu Shirasuna
Pages: 2021-2028
Published online on: 17 October 2012

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Article

Diallyl trisulfide sensitizes human melanoma cells to TRAIL-induced cell death by promoting endoplasmic reticulum-mediated apoptosis

Mayumi Murai, Toshio Inoue, Miki Suzuki-Karasaki, Toyoko Ochiai, Chisei Ra, Sigeru Nishida, Yoshihiro Suzuki-Karasaki
Pages: 2029-2037
Published online on: 11 October 2012

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Article

Differential DNA copy number aberrations in the progression of cervical lesions to invasive cervical carcinoma

Eun Kyeong Oh, Yong-Wan Kim, In-Wook Kim, Hai-Bo Liu, Keun-Ho Lee, Heung Jae Chun, Dong Choon Park, Eun-Jee Oh, Ah Won Lee, Su Mi Bae, Woong Shick Ahn
Pages: 2038-2046
Published online on: 27 September 2012

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Article

Establishment of a bioluminescent imaging-based in vivo leukemia model by intra-bone marrow injection

Myoung Woo Lee, Hye Jin Kim, Keon Hee Yoo, Dae Seong Kim, Jin Mo Yang, Hye Ryung Kim, Yoo Hun Noh, Hyunjung Baek, Heechung Kwon, Meong Hi Son, Soo Hyun Lee, Hee Won Cheuh, Hye Lim Jung, Ki Woong Sung, Hong Hoe Koo
Pages: 2047-2056
Published online on: 20 September 2012

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Article

Novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, MHY-449, induces apoptosis and cell cycle arrest in HCT116 human colon cancer cells

Hye Jung Hwang, Yong Jung Kang, Mohammad Akbar Hossain, Dong Hwan Kim, Jung Yoon Jang, Sun Hwa Lee, Jeong-Hyun Yoon, Hyung Ryong Moon, Hyung Sik Kim, Hae Young Chung, Nam Deuk Kim
Pages: 2057-2064
Published online on: 11 October 2012

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Article

ERK-modulated intrinsic signaling and G2/M phase arrest contribute to the induction of apoptotic death by allyl isothiocyanate in MDA-MB-468 human breast adenocarcinoma cells

Shih-Chang Tsai, Wen-Wen Huang, Wei-Chien Huang, Chi-Cheng Lu, Jo-Hua Chiang, Shu-Fen Peng, Jing-Gung Chung, Yu-Hsin Lin, Yuan-Man Hsu, Sakae Amagaya, Jai-Sing Yang
Pages: 2065-2072
Published online on: 24 September 2012

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Article

Induced lymphatic sinus hyperplasia in sentinel lymph nodes by VEGF-C as the earliest premetastatic indicator

Ruediger Liersch, Satoshi Hirakawa, Wolfgang E. Berdel, Rolf M. Mesters, Michael Detmar
Pages: 2073-2078
Published online on: 16 October 2012

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Article

PARP6, a mono(ADP-ribosyl) transferase and a negative regulator of cell proliferation, is involved in colorectal cancer development

Handan Tuncel, Shinji Tanaka, Shiro Oka, Shiro Nakai, Ryuichiro Fukutomi, Mayumi Okamoto, Takahide Ota, Hiroshi Kaneko, Masaaki Tatsuka, Fumio Shimamoto
Pages: 2079-2086
Published online on: 04 October 2012

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Article

Prolonged androgen deprivation leads to downregulation of androgen receptor and prostate-specific membrane antigen in prostate cancer cells

Tiancheng Liu, Lisa Y. Wu, Melody D. Fulton, Jacqueline M. Johnson, Clifford E. Berkman
Pages: 2087-2092
Published online on: 04 October 2012

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Article

Pancreatic cancer cells surviving gemcitabine treatment express markers of stem cell differentiation and epithelial-mesenchymal transition

Karl Quint, Manuel Tonigold, Pietro Di Fazio, Roberta Montalbano, Susanne Lingelbach, Felix Rückert, Beate Alinger, Matthias Ocker, Daniel Neureiter
Pages: 2093-2102
Published online on: 01 October 2012

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Article

The relationship between tissue oxygenation and redox status using magnetic resonance imaging

Fuminori Hyodo, Ryan M. Davis, Emi Hyodo, Shingo Matsumoto, Murali C. Krishna, James B. Mitchell
Pages: 2103-2108
Published online on: 24 September 2012

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Article

Intracellular localization of mesothelin predicts patient prognosis of extrahepatic bile duct cancer

Futoshi Kawamata, Hirofumi Kamachi, Takahiro Einama, Shigenori Homma, Munenori Tahara, Masaya Miyazaki, Shinya Tanaka, Toshiya Kamiyama, Hiroshi Nishihara, Akinobu Taketomi, Satoru Todo
Pages: 2109-2118
Published online on: 15 October 2012

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Article

Peptide nucleic acids targeting miR-221 modulate p27Kip1 expression in breast cancer MDA-MB-231 cells

Eleonora Brognara, Enrica Fabbri, Fabio Aimi, Alex Manicardi, Nicoletta Bianchi, Alessia Finotti, Giulia Breveglieri , Monica Borgatti, Roberto Corradini, Rosangela Marchelli, Roberto Gambari
Pages: 2119-2127
Published online on: 19 September 2012

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Article

Involvement of the Src-cortactin pathway in migration induced by IGF-1 and EGF in human breast cancer cells

Silvia Mezi, Laura Todi, Errico Orsi, Antonio Angeloni, Patrizia Mancini
Pages: 2128-2138
Published online on: 26 September 2012

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Article

The effect of Aurora kinases on cell proliferation, cell cycle regulation and metastasis in renal cell carcinoma

Yan Li, Wanqi Zhou, Langli Wei, Jing Jin, Ke Tang, Chao Li, Bin Tean Teh, Xiaoguang Chen
Pages: 2139-2149
Published online on: 20 September 2012

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Article

Expression and role of epithelial cell adhesion molecule in dysplastic nodule and hepatocellular carcinoma

Jun Sang Bae, Sang Jae Noh, Kyu Yun Jang, Ho Sung Park, Myoung Ja Chung, Cheol Keun Park, Woo Sung Moon
Pages: 2150-2158
Published online on: 19 September 2012

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Article

A novel Ad5/11 chimeric oncolytic adenovirus for improved glioma therapy

Xing Li, Qinwen Mao, Dongyang Wang, Haibin Xia
Pages: 2159-2165
Published online on: 18 October 2012

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Article

Identification of recurrence-related genes by integrating microRNA and gene expression profiling of gastric cancer

Zhi Yan, Yimin Xiong, Weitian Xu, Min Li, Yi Cheng, Fang Chen, Shifang Ding, Hualin Xu, Guorong Zheng
Pages: 2166-2174
Published online on: 24 September 2012

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Article

Conditionally replicating adenovirus SG500-expressed mutant Dm-dNK gene for breast cancer therapy

Wenzhi Qu, Zhi Zhu, Lei Zhao, Anning He, Xinyu Zheng
Pages: 2175-2183
Published online on: 11 October 2012

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Article

Combination treatment with photodynamic therapy and curcumin induces mitochondria-dependent apoptosis in AMC-HN3 cells

Jin-Chul Ahn, Jung-Wook Kang, Jang-In Shin, Phil-Sang Chung
Pages: 2184-2190
Published online on: 15 October 2012

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Article

Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt

Sivalokanathan Sarveswaran, Subhash C. Gautam, Jagadananda Ghosh
Pages: 2191-2199
Published online on: 16 October 2012

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Article

Serum protein levels following surgery in breast cancer patients: A protein microarray approach

Luis G. Perez-Rivas, Jose M. Jerez, Cristina E. Fernandez-De Sousa, Vanessa de Luque, Cristina Quero, Bella Pajares, Leonardo  Franco, Alfonso Sanchez-Muñoz, Nuria Ribelles, Emilio Alba
Pages: 2200-2206
Published online on: 16 October 2012

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Article

Dietary resveratrol does not delay engraftment, sensitize to vincristine or inhibit growth of high-risk acute lymphoblastic leukemia cells in NOD/SCID mice

Susan J. Zunino, David H. Storms, John W. Newman, Theresa L. Pedersen, Carl L. Keen, Jonathan M. Ducore
Pages: 2207-2212
Published online on: 04 October 2012

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Article

Pathway analysis of cancer-associated microRNA targets

Hao Yang, Haiyang Zhang, Lin Zhu, Jin Wang, Chenyu Zhang, Donghai Li
Pages: 2213-2226
Published online on: 11 October 2012

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Article

BML-275, an AMPK inhibitor, induces DNA damage, G2/M arrest and apoptosis in human pancreatic cancer cells

Hong-Quan Duong, Jae Seok Hwang, Hee Jeong Kim, Yeon-Sun Seong, Insoo Bae
Pages: 2227-2236
Published online on: 17 October 2012

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Article

microRNAs and zinc metabolism-related gene expression in prostate cancer cell lines treated with zinc(II) ions

Marian Hlavna, Martina Raudenska, Kristyna Hudcova, Jaromir Gumulec, Marketa Sztalmachova, Veronika Tanhäuserova, Petr Babula, Vojtech Adam, Tomas Eckschlager, Rene Kizek, Michal Masarik
Pages: 2237-2244
Published online on: 09 October 2012

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Article

Action of bleomycin is affected by bleomycin hydrolase but not by caveolin-1

Jianguo Chen, Yang Chen, Qiyang He
Pages: 2245-2252
Published online on: 16 October 2012

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Article

Regulation of CXCR4 gene expression in breast cancer cells under diverse stress conditions

Kleopatra Andreou, Ramkumar Rajendran, Marija Krstic-Demonacos, Constantinos Demonacos
Pages: 2253-2259
Published online on: 27 September 2012

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Article

Chemoprevention of pancreatic cancer using solid-lipid nanoparticulate delivery of a novel aspirin, curcumin and sulforaphane drug combination regimen

Dhruvitkumar Sutaria, Balagangadhar Karthik Grandhi, Arvind Thakkar, Jeffrey Wang, Sunil Prabhu
Pages: 2260-2268
Published online on: 21 September 2012

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Article

Effects of 12-O-tetradecanoylphorbol-13-acetate in combination with gemcitabine on Panc-1 pancreatic cancer cells cultured in vitro or Panc-1 tumors grown in immunodeficient mice

Xi Zheng, Xiao-Xing Cui, Zhi Gao, Michael Verano, Mou‑Tuan  Huang, Yue Liu, Arnold B. Rabson, Allan H. Conney
Pages: 2269-2275
Published online on: 04 October 2012

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Article

The selective Hsp90 inhibitor BJ-B11 exhibits potent antitumor activity via induction of cell cycle arrest, apoptosis and autophagy in Eca-109 human esophageal squamous carcinoma cells

Kai-Sheng Liu, Yi Zhang, Wei-Chao Ding, Shao-Xiang Wang, Yang-Fei Xiang, Pan Yang, Zhen-Ping Chen, Kai Zheng, Zhong Liu, Min Xia, Yi-Fei Wang
Pages: 2276-2284
Published online on: 17 October 2012

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Article

The prolactin receptor mediates HOXA1-stimulated oncogenicity in mammary carcinoma cells

Lin Hou, Bing Xu, Kumarasamypet M. Mohankumar, Vincent Goffin, Jo K. Perry, Peter E. Lobie, Dong-Xu Liu
Pages: 2285-2295
Published online on: 15 October 2012

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Journal Cover
March-2026 Volume 68 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Circ72309 modulates gemcitabine metabolism and gemcitabine sensitivity in pancreatic cancer: Serum Circ72309 levels as a potential predictor of treatment response

Naoko Sekiguchi, Hidenori Takahashi, Shogo Kobayashi, Kazuki Sasaki, Shinichiro Hasegawa, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Hirofumi Akita, Tadafumi Asaoka, Takehiro Noda, Junzo Shimizu, Koji Tanaka, Ryota Chijimatsu, Yuichiro Doki, Hidetoshi Eguchi
Article Number: 36
Published online on: 16 January 2026

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Review Open Access

Unveiling sex differences in pancreatic ductal adenocarcinoma: Current evidence and future directions (Review)

Sophie Rauschenberg, Elisabeth Orgler‑Gasche, Didem Karakas Zeybek, Ivonne Regel, J.-Matthias Löhr, Daniel Öhlund, Michael Günther, Lina Aguilera Munoz
Article Number: 35
Published online on: 15 January 2026

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Retraction Open Access

[Retracted] LTBP2 promotes the migration and invasion of gastric cancer cells and predicts poor outcome of patients with gastric cancer

Jun Wang, Wen-Jia Liang, Guang-Tao Min, Hong-Peng Wang, Wei Chen, Nan Yao
Article Number: 34
Published online on: 13 January 2026

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Article Open Access

KMO downregulation promotes hepatocellular carcinoma growth via 3‑HAA‑mediated mitochondrial mass and function imbalances

Ming Liu, Xintong Zhang, Yanfen Hu, Li Niu, Linzhi Guo, Guoqing Zhao, Fan Lu, Fengfeng Jia, Li Li, Hao Wu, Jianjun Zhu
Article Number: 33
Published online on: 13 January 2026

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Review Open Access

Regulatory networks of HIFs in tumor‑infiltrating immune cells: From molecular mechanisms to therapeutic implications (Review)

Chaoqun Li, Chenge Qin, Xingchen Li, Jinzhu Wang, Yang Li, Qin Sun
Article Number: 32
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] uPAR and cathepsin B knockdown inhibits radiation‑induced PKC integrated integrin signaling to the cytoskeleton of glioma‑initiating cells

Kiranmai Alapati, Sreelatha Gopinath, Rama Rao Malla, Venkata Ramesh Dasari, Jasti S. Rao
Article Number: 31
Published online on: 05 January 2026

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Article Open Access

PTPN18 functions as a tumor suppressor in breast cancer by negatively regulating cyclin E

Na Zhang, Tao Wang, Bin Bai, Xiaonan Zhang, Wenying Xu, Weilu Chen, Yang Yu, Bing Wang
Article Number: 30
Published online on: 30 December 2025

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Retraction Open Access

[Retracted] Suppression of the death gene BIK is a critical factor for resistance to tamoxifen in MCF‑7 breast cancer cells

Rubí Viedma-Rodriguez, Luis Arturo Baiza-Gutman, Alejandro García-Carrancá, Leticia Moreno-Fierros, Fabio Salamanca-Gómez, Diego Arenas-Aranda
Article Number: 29
Published online on: 23 December 2025

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Review Open Access

Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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