Journal Articles

Circulating microRNAs: New biomarkers in diagnosis, prognosis and treatment of cancer (Review)

Alessandro Allegra, Andrea Alonci, Salvatore Campo, Giuseppa Penna, Annamaria Petrungaro, Demetrio Gerace, Caterina Musolino

Pages: 1897-1912 Published online on: 01 October 2012
Open Access

Function and cancer genomics of FAT family genes (Review)

Masaru Katoh

Pages: 1913-1918 Published online on: 17 October 2012

The insulin-like growth factor (IGF) signaling axis and hepatitis C virus-associated carcinogenesis (Review)

Aldona Kasprzak, Agnieszka Adamek

Pages: 1919-1931 Published online on: 16 October 2012
Open Access

Established breast cancer stem cell markers do not correlate with in vivo tumorigenicity of tumor-initiating cells

Christian Lehmann, Gabriele Jobs, Markus Thomas, Helmut Burtscher, Manfred Kubbies

Pages: 1932-1942 Published online on: 05 October 2012
Open Access

Ciprofloxacin is a potential topoisomerase II inhibitor for the treatment of NSCLC

Tomasz Kloskowski, Natalia Gurtowska, Joanna Olkowska, Jakub Marcin Nowak, Jan  Adamowicz, Jakub Tworkiewicz, Robert Dębski, Alina Grzanka, Tomasz Drewa

Pages: 1943-1949 Published online on: 04 October 2012
Open Access

Cell type and context-specific function of PLAG1 for IGF2 P3 promoter activity

Monira Akhtar, Claes Holmgren, Anita Göndör, Mattias Vesterlund, Chandrasekhar Kanduri, Catharina Larsson, Tomas J. Ekström

Pages: 1959-1966 Published online on: 26 September 2012
Open Access

Downregulation of protein kinase CK2 induces autophagic cell death through modulation of the mTOR and MAPK signaling pathways in human glioblastoma cells

Birgitte B. Olsen, Tina H. Svenstrup, Barbara Guerra

Pages: 1967-1976 Published online on: 21 September 2012
Open Access

MUC1 glycopeptide epitopes predicted by computational glycomics

Wei Song, Elizabeth S. Delyria, Jieqing Chen, Wei Huang, Jun Soo Lee, Elizabeth A. Mittendorf, Nuhad Ibrahim, Laszlo G. Radvanyi, Yunsen Li, Hongzhou Lu, Huaxi Xu, Yinqiang Shi, Lai-Xi Wang, Jeremy A. Ross, Silas P. Rodrigues, Igor C. Almeida, Xifeng Yang, Jin Qu, Nathaniel S. Schocker, Katja Michael, Dapeng Zhou

Pages: 1977-1984 Published online on: 27 September 2012
Open Access

T-box transcription factor Brachyury expression is correlated with epithelial-mesenchymal transition and lymph node metastasis in oral squamous cell carcinoma

Ikumi Imajyo, Tsuyoshi Sugiura, Yosuke Kobayashi, Miyuki Shimoda, Kotaro Ishii, Naonari Akimoto, Naoya Yoshihama, Ieyoshi Kobayashi, Yoshihide Mori

Pages: 1985-1995 Published online on: 17 October 2012
Open Access

In vitro and in vivo inhibition of human Fanconi anemia-associated head and neck squamous cell carcinoma by a novel nutrient mixture

M. W. Roomi, T. Kalinovsky, N. W. Roomi, A. Niedzwiecki, M. Rath

Pages: 1996-2004 Published online on: 24 September 2012

Hypoxia downregulates the expression of cell surface MICA without increasing soluble MICA in osteosarcoma cells in a HIF-1α-dependent manner

Naoko Yamada, Koji Yamanegi, Hideki Ohyama, Masaki Hata, Keiji Nakasho, Hiroyuki Futani, Haruki Okamura, Nobuyuki Terada

Pages: 2005-2012 Published online on: 18 September 2012

Genomic copy number alterations associated with the early brain metastasis of non-small cell lung cancer

Hye Won Lee, Ho Jun Seol, Yoon-La Choi, Hyun Jung Ju, Kyeung Min Joo, Young-Hyeh Ko, Jung-Il Lee, Do-Hyun Nam

Pages: 2013-2020 Published online on: 15 October 2012
Open Access

CD82 inhibits canonical Wnt signalling by controlling the cellular distribution of β-catenin in carcinoma cells

Satomi Chigita, Tsuyoshi Sugiura, Masakazu Abe, Yosuke Kobayashi, Miyuki Shimoda, Megumi Onoda, Kanemitsu Shirasuna

Pages: 2021-2028 Published online on: 17 October 2012

Diallyl trisulfide sensitizes human melanoma cells to TRAIL-induced cell death by promoting endoplasmic reticulum-mediated apoptosis

Mayumi Murai, Toshio Inoue, Miki Suzuki-Karasaki, Toyoko Ochiai, Chisei Ra, Sigeru Nishida, Yoshihiro Suzuki-Karasaki

Pages: 2029-2037 Published online on: 11 October 2012

Differential DNA copy number aberrations in the progression of cervical lesions to invasive cervical carcinoma

Eun Kyeong Oh, Yong-Wan Kim, In-Wook Kim, Hai-Bo Liu, Keun-Ho Lee, Heung Jae Chun, Dong Choon Park, Eun-Jee Oh, Ah Won Lee, Su Mi Bae, Woong Shick Ahn

Pages: 2038-2046 Published online on: 27 September 2012

Establishment of a bioluminescent imaging-based in vivo leukemia model by intra-bone marrow injection

Myoung Woo Lee, Hye Jin Kim, Keon Hee Yoo, Dae Seong Kim, Jin Mo Yang, Hye Ryung Kim, Yoo Hun Noh, Hyunjung Baek, Heechung Kwon, Meong Hi Son, Soo Hyun Lee, Hee Won Cheuh, Hye Lim Jung, Ki Woong Sung, Hong Hoe Koo

Pages: 2047-2056 Published online on: 20 September 2012

Novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, MHY-449, induces apoptosis and cell cycle arrest in HCT116 human colon cancer cells

Hye Jung Hwang, Yong Jung Kang, Mohammad Akbar Hossain, Dong Hwan Kim, Jung Yoon Jang, Sun Hwa Lee, Jeong-Hyun Yoon, Hyung Ryong Moon, Hyung Sik Kim, Hae Young Chung, Nam Deuk Kim

Pages: 2057-2064 Published online on: 11 October 2012

ERK-modulated intrinsic signaling and G2/M phase arrest contribute to the induction of apoptotic death by allyl isothiocyanate in MDA-MB-468 human breast adenocarcinoma cells

Shih-Chang Tsai, Wen-Wen Huang, Wei-Chien Huang, Chi-Cheng Lu, Jo-Hua Chiang, Shu-Fen Peng, Jing-Gung Chung, Yu-Hsin Lin, Yuan-Man Hsu, Sakae Amagaya, Jai-Sing Yang

Pages: 2065-2072 Published online on: 24 September 2012

Induced lymphatic sinus hyperplasia in sentinel lymph nodes by VEGF-C as the earliest premetastatic indicator

Ruediger Liersch, Satoshi Hirakawa, Wolfgang E. Berdel, Rolf M. Mesters, Michael Detmar

Pages: 2073-2078 Published online on: 16 October 2012

PARP6, a mono(ADP-ribosyl) transferase and a negative regulator of cell proliferation, is involved in colorectal cancer development

Handan Tuncel, Shinji Tanaka, Shiro Oka, Shiro Nakai, Ryuichiro Fukutomi, Mayumi Okamoto, Takahide Ota, Hiroshi Kaneko, Masaaki Tatsuka, Fumio Shimamoto

Pages: 2079-2086 Published online on: 04 October 2012

Prolonged androgen deprivation leads to downregulation of androgen receptor and prostate-specific membrane antigen in prostate cancer cells

Tiancheng Liu, Lisa Y. Wu, Melody D. Fulton, Jacqueline M. Johnson, Clifford E. Berkman

Pages: 2087-2092 Published online on: 04 October 2012

Pancreatic cancer cells surviving gemcitabine treatment express markers of stem cell differentiation and epithelial-mesenchymal transition

Karl Quint, Manuel Tonigold, Pietro Di Fazio, Roberta Montalbano, Susanne Lingelbach, Felix Rückert, Beate Alinger, Matthias Ocker, Daniel Neureiter

Pages: 2093-2102 Published online on: 01 October 2012

The relationship between tissue oxygenation and redox status using magnetic resonance imaging

Fuminori Hyodo, Ryan M. Davis, Emi Hyodo, Shingo Matsumoto, Murali C. Krishna, James B. Mitchell

Pages: 2103-2108 Published online on: 24 September 2012

Intracellular localization of mesothelin predicts patient prognosis of extrahepatic bile duct cancer

Futoshi Kawamata, Hirofumi Kamachi, Takahiro Einama, Shigenori Homma, Munenori Tahara, Masaya Miyazaki, Shinya Tanaka, Toshiya Kamiyama, Hiroshi Nishihara, Akinobu Taketomi, Satoru Todo

Pages: 2109-2118 Published online on: 15 October 2012

Peptide nucleic acids targeting miR-221 modulate p27Kip1 expression in breast cancer MDA-MB-231 cells

Eleonora Brognara, Enrica Fabbri, Fabio Aimi, Alex Manicardi, Nicoletta Bianchi, Alessia Finotti, Giulia Breveglieri , Monica Borgatti, Roberto Corradini, Rosangela Marchelli, Roberto Gambari

Pages: 2119-2127 Published online on: 19 September 2012

Involvement of the Src-cortactin pathway in migration induced by IGF-1 and EGF in human breast cancer cells

Silvia Mezi, Laura Todi, Errico Orsi, Antonio Angeloni, Patrizia Mancini

Pages: 2128-2138 Published online on: 26 September 2012

The effect of Aurora kinases on cell proliferation, cell cycle regulation and metastasis in renal cell carcinoma

Yan Li, Wanqi Zhou, Langli Wei, Jing Jin, Ke Tang, Chao Li, Bin Tean Teh, Xiaoguang Chen

Pages: 2139-2149 Published online on: 20 September 2012

Expression and role of epithelial cell adhesion molecule in dysplastic nodule and hepatocellular carcinoma

Jun Sang Bae, Sang Jae Noh, Kyu Yun Jang, Ho Sung Park, Myoung Ja Chung, Cheol Keun Park, Woo Sung Moon

Pages: 2150-2158 Published online on: 19 September 2012

A novel Ad5/11 chimeric oncolytic adenovirus for improved glioma therapy

Xing Li, Qinwen Mao, Dongyang Wang, Haibin Xia

Pages: 2159-2165 Published online on: 18 October 2012

Identification of recurrence-related genes by integrating microRNA and gene expression profiling of gastric cancer

Zhi Yan, Yimin Xiong, Weitian Xu, Min Li, Yi Cheng, Fang Chen, Shifang Ding, Hualin Xu, Guorong Zheng

Pages: 2166-2174 Published online on: 24 September 2012

Conditionally replicating adenovirus SG500-expressed mutant Dm-dNK gene for breast cancer therapy

Wenzhi Qu, Zhi Zhu, Lei Zhao, Anning He, Xinyu Zheng

Pages: 2175-2183 Published online on: 11 October 2012

Combination treatment with photodynamic therapy and curcumin induces mitochondria-dependent apoptosis in AMC-HN3 cells

Jin-Chul Ahn, Jung-Wook Kang, Jang-In Shin, Phil-Sang Chung

Pages: 2184-2190 Published online on: 15 October 2012

Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt

Sivalokanathan Sarveswaran, Subhash C. Gautam, Jagadananda Ghosh

Pages: 2191-2199 Published online on: 16 October 2012

Serum protein levels following surgery in breast cancer patients: A protein microarray approach

Luis G. Perez-Rivas, Jose M. Jerez, Cristina E. Fernandez-De Sousa, Vanessa de Luque, Cristina Quero, Bella Pajares, Leonardo  Franco, Alfonso Sanchez-Muñoz, Nuria Ribelles, Emilio Alba

Pages: 2200-2206 Published online on: 16 October 2012

Dietary resveratrol does not delay engraftment, sensitize to vincristine or inhibit growth of high-risk acute lymphoblastic leukemia cells in NOD/SCID mice

Susan J. Zunino, David H. Storms, John W. Newman, Theresa L. Pedersen, Carl L. Keen, Jonathan M. Ducore

Pages: 2207-2212 Published online on: 04 October 2012

Pathway analysis of cancer-associated microRNA targets

Hao Yang, Haiyang Zhang, Lin Zhu, Jin Wang, Chenyu Zhang, Donghai Li

Pages: 2213-2226 Published online on: 11 October 2012

BML-275, an AMPK inhibitor, induces DNA damage, G2/M arrest and apoptosis in human pancreatic cancer cells

Hong-Quan Duong, Jae Seok Hwang, Hee Jeong Kim, Yeon-Sun Seong, Insoo Bae

Pages: 2227-2236 Published online on: 17 October 2012

microRNAs and zinc metabolism-related gene expression in prostate cancer cell lines treated with zinc(II) ions

Marian Hlavna, Martina Raudenska, Kristyna Hudcova, Jaromir Gumulec, Marketa Sztalmachova, Veronika Tanhäuserova, Petr Babula, Vojtech Adam, Tomas Eckschlager, Rene Kizek, Michal Masarik

Pages: 2237-2244 Published online on: 09 October 2012

Action of bleomycin is affected by bleomycin hydrolase but not by caveolin-1

Jianguo Chen, Yang Chen, Qiyang He

Pages: 2245-2252 Published online on: 16 October 2012

Regulation of CXCR4 gene expression in breast cancer cells under diverse stress conditions

Kleopatra Andreou, Ramkumar Rajendran, Marija Krstic-Demonacos, Constantinos Demonacos

Pages: 2253-2259 Published online on: 27 September 2012

Chemoprevention of pancreatic cancer using solid-lipid nanoparticulate delivery of a novel aspirin, curcumin and sulforaphane drug combination regimen

Dhruvitkumar Sutaria, Balagangadhar Karthik Grandhi, Arvind Thakkar, Jeffrey Wang, Sunil Prabhu

Pages: 2260-2268 Published online on: 21 September 2012

Effects of 12-O-tetradecanoylphorbol-13-acetate in combination with gemcitabine on Panc-1 pancreatic cancer cells cultured in vitro or Panc-1 tumors grown in immunodeficient mice

Xi Zheng, Xiao-Xing Cui, Zhi Gao, Michael Verano, Mou‑Tuan  Huang, Yue Liu, Arnold B. Rabson, Allan H. Conney

Pages: 2269-2275 Published online on: 04 October 2012

The selective Hsp90 inhibitor BJ-B11 exhibits potent antitumor activity via induction of cell cycle arrest, apoptosis and autophagy in Eca-109 human esophageal squamous carcinoma cells

Kai-Sheng Liu, Yi Zhang, Wei-Chao Ding, Shao-Xiang Wang, Yang-Fei Xiang, Pan Yang, Zhen-Ping Chen, Kai Zheng, Zhong Liu, Min Xia, Yi-Fei Wang

Pages: 2276-2284 Published online on: 17 October 2012

The prolactin receptor mediates HOXA1-stimulated oncogenicity in mammary carcinoma cells

Lin Hou, Bing Xu, Kumarasamypet M. Mohankumar, Vincent Goffin, Jo K. Perry, Peter E. Lobie, Dong-Xu Liu

Pages: 2285-2295 Published online on: 15 October 2012
Journal Cover

Cover Legend PDF

December 2012
Volume 41 Issue 6

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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