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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2013 Volume 43 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Hospicells promote upregulation of the ATP-binding cassette genes by insulin-like growth factor-I via the JAK2/STAT3 signaling pathway in an ovarian cancer cell line

Nadia Benabbou, Pezhman Mirshahi, Mélodie Cadillon, Jeannette Soria, Amu Therwath, Massoud Mirshahi
Pages: 685-694
Published online on: 15 July 2013

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Article Open Access

Anti-apoptotic role of the sonic hedgehog signaling pathway in the proliferation of ameloblastoma

Shiori Kanda, Takeshi Mitsuyasu, Yu Nakao, Shintaro Kawano, Yuichi Goto, Ryota Matsubara, Seiji Nakamura
Pages: 695-702
Published online on: 08 July 2013

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Article Open Access

‘Decoy’ and ‘non-decoy’ functions of DcR3 promote malignant potential in human malignant fibrous histiocytoma cells

Mitsunori Toda, Teruya Kawamoto, Takeshi Ueha, Kenta Kishimoto, Hitomi Hara, Naomasa Fukase, Yasuo Onishi, Risa Harada, Masaya Minoda, Masahiro Kurosaka, Toshihiro Akisue
Pages: 703-712
Published online on: 28 June 2013

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Article

Substitution of anti-androgens and tegafur-uracil combination therapy for castration-resistant prostate cancer: Results of a multi-center randomized phase II study

Masayuki Takahashi, Rumi Kawabata, Akira Kawano, Yoshihide Murakami, Yasushi Sutou, Tohru Inai, Seiji Akazawa, Takumi Hamao, Hideki Hayashi, Tomoya Fukawa, Masahiko Takemura, Yasuyo Yamamoto, Kunihisa Yamaguchi, Hirofumi Izaki, Tomoharu Fukumori, Hiroomi Kanayama
Pages: 713-720
Published online on: 28 June 2013

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Article

β-Elemene enhances susceptibility to cisplatin in resistant ovarian carcinoma cells via downregulation of ERCC-1 and XIAP and inactivation of JNK

Quentin Q. Li, Rebecca X. Lee, Huasheng Liang, Gangduo Wang, Jueli M. Li, Yuhua Zhong, Eddie Reed
Pages: 721-728
Published online on: 28 June 2013

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Article

Proteomic identification of keratin alterations with enhanced proliferation of oral carcinoma cells by loss of mucosa-associated lymphoid tissue 1 expression

Yukihiro Kawamoto, Yoshito Ohyama, Tadashige Chiba, Hisao Yagishita, Hideaki Sakashita, Kazushi Imai
Pages: 729-736
Published online on: 25 June 2013

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Article

Effect of a nitric oxide synthase inhibitor and a CXC chemokine receptor-4 antagonist on tumor growth and metastasis in a xenotransplanted mouse model of adenoid cystic carcinoma of the oral floor

Kazuki Takaoka, Sayaka Hidaka, Susumu Hashitani, Emi Segawa, Michiyo Yamamura, Noriaki Tanaka, Yusuke Zushi, Kazuma Noguchi, Hiromitsu Kishimoto, Masahiro Urade
Pages: 737-745
Published online on: 08 July 2013

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Article

VEGF expression is augmented by hypoxia‑induced PGIS in human fibroblasts

Jia Wang, Ryuji Ikeda, Xiao-Fang Che, Akio Ooyama, Masatatsu Yamamoto, Tatsuhiko Furukawa, Kazuhisa Hasui, Chun-Lei Zheng, Yusuke Tajitsu, Toshinori Oka, Sho Tabata, Yukihiko Nishizawa, Yoshito Eizuru, Shin-Ichi Akiyama
Pages: 746-754
Published online on: 27 June 2013

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Article

Whole-exome sequencing to identify novel somatic mutations in squamous cell lung cancers

Cui-Xia Zheng, Zhao-Hui Gu, Bing Han, Rong-Xin Zhang, Chun-Ming Pan, Yi Xiang, Xia-Jun Rong, Xia Chen, Qing-Yun Li, Huan-Ying Wan
Pages: 755-764
Published online on: 25 June 2013

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Article

Let-7g and miR-21 expression in non-small cell lung cancer: Correlation with clinicopathological and molecular features

Alessandra Capodanno, Laura Boldrini, Agnese Proietti, Greta Alì, Serena Pelliccioni, Cristina Niccoli, Armida D'Incecco, Federico Cappuzzo, Antonio Chella, Marco Lucchi, Alfredo Mussi, Gabriella Fontanini
Pages: 765-774
Published online on: 02 July 2013

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Article

Mucin-like peptides from Echinococcus granulosus induce antitumor activity

Verónica Noya, Sylvie Bay, María Florencia Festari, Enrique P. García, Ernesto Rodriguez, Carolina Chiale, Christelle Ganneau, Françoise Baleux, Soledad Astrada, Mariela Bollati-Fogolín, Eduardo Osinaga, Teresa Freire
Pages: 775-784
Published online on: 28 June 2013

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Article

Raloxifene reduces triple-negative breast cancer tumor growth and decreases EGFR expression

Sebastien Taurin, Kirstie M. Allen, Marissa J. Scandlyn, Rhonda J. Rosengren
Pages: 785-792
Published online on: 10 July 2013

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Article

Overexpression of Bmi-1 contributes to the invasion and metastasis of hepatocellular carcinoma by increasing the expression of matrix metalloproteinase (MMP)‑2, MMP-9 and vascular endothelial growth factor via the PTEN/PI3K/Akt pathway

Xiaolei Li, Zhaoxu Yang, Wenjie Song, Liang Zhou, Qingjun Li, Kaishan Tao, Jingshi Zhou, Xing Wang, Zhigang Zheng, Nan You, Kefeng Dou, Haimin Li
Pages: 793-802
Published online on: 26 June 2013

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Article

The dual inhibitory effect of thiostrepton on FoxM1 and EWS/FLI1 provides a novel therapeutic option for Ewing's sarcoma

Aniruddha Sengupta, Mahbubur Rahman, Silvia Mateo-Lozano, Oscar M. Tirado, Vicente Notario
Pages: 803-812
Published online on: 12 July 2013

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Article

Reactive oxygen species spermine metabolites generated from amine oxidases and radiation represent a therapeutic gain in cancer treatments

Roberto Amendola, Manuela Cervelli, Emiliano Fratini, Davide E. Sallustio, Giampiero Tempera, Taichi Ueshima, Paolo Mariottini, Enzo Agostinelli
Pages: 813-820
Published online on: 12 July 2013

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Article

PDCD5 expression predicts a favorable outcome in patients with hepatocellular carcinoma

Da-Zhi Fu, Ying Cheng, Hui He, Hai-Yang Liu, Yong-Feng Liu
Pages: 821-830
Published online on: 26 June 2013

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Article

Neuroblastoma cells injected into experimental mature teratoma reveal a tropism for embryonic loose mesenchyme

S. Jamil, J. Cedervall, I. Hultman, R. Ali, N. V. Margaryan, A. Rasmuson, J. I. Johnsen, B. Sveinbjörnsson, T. Dalianis, L. Kanter, A. Orrego, L. Strizzi, M. J.C. Hendrix, B. Sandstedt, P. Kogner, L. Ährlund-Richter
Pages: 831-838
Published online on: 12 July 2013

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Article

miRNA expression pattern associated with prognosis in elderly patients with advanced OPSC and OCC

Henan Zhao, Yanfang Ding, Bi Tie, Zhen-Feng Sun, Ji-Yong Jiang, Jinyao Zhao, Xingchi Lin, Shiying Cui
Pages: 839-849
Published online on: 20 June 2013

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Article

CD59 is overexpressed in human lung cancer and regulates apoptosis of human lung cancer cells

Baijun Li, Hui Lin, Jian Fan, Jiao Lan, Yonglong Zhong, Yong Yang, Hui Li, Zhiwei Wang
Pages: 850-858
Published online on: 05 July 2013

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Article

Trop2 regulates the proliferation and differentiation of murine compact-bone derived MSCs

Jianye Yang, Zhaohui Zhu, Hongfei Wang, Feifei Li, Xinling Du, Runlin Z. Ma
Pages: 859-867
Published online on: 19 June 2013

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Article

(-)-Epigallocatechin-3-gallate blocks nicotine-induced matrix metalloproteinase-9 expression and invasiveness via suppression of NF-κB and AP-1 in endothelial cells

Pham Ngoc Khoi, Jung Sun Park, Jin Hee Kim, Yong Xia, Nam Ho Kim, Kyung Keun Kim, Young Do Jung
Pages: 868-876
Published online on: 05 July 2013

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Article

CEACAM6 induces epithelial-mesenchymal transition and mediates invasion and metastasis in pancreatic cancer

Jianmin Chen, Qiang Li, Yong An, Nan Lv, Xiaofeng Xue, Jishu Wei, Kuirong Jiang, Junli Wu, Wentao Gao, Zhuyin Qian, Cuncai Dai, Zekuan Xu, Yi Miao
Pages: 877-885
Published online on: 12 July 2013

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Article

Skeletal muscle mitochondrial uncoupling in a murine cancer cachexia model

A. Aria Tzika, Cibely Cristine Fontes-Oliveira, Alexander A. Shestov, Caterina Constantinou, Nikolaos Psychogios, Valeria Righi, Dionyssios Mintzopoulos, Silvia Busquets, Francisco J. Lopez-Soriano, Sylvain Milot, Francois Lepine, Michael N. Mindrinos, Laurence G. Rahme, Josep M. Argiles
Pages: 886-894
Published online on: 28 June 2013

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Article

Curcumin enhances the lung cancer chemopreventive efficacy of phospho-sulindac by improving its pharmacokinetics

Ka-Wing Cheng, Chi C. Wong, George Mattheolabakis, Gang Xie, Liqun Huang, Basil Rigas
Pages: 895-902
Published online on: 27 June 2013

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Article

A new model to evaluate Raf signaling in hematopoietic cells

Keiko Okuda
Pages: 903-910
Published online on: 02 July 2013

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Article

Effects of combined phytochemicals on skin tumorigenesis in SENCAR mice

Magdalena C. Kowalczyk, Jacob J. Junco, Piotr Kowalczyk, Olga Tolstykh, Margaret Hanausek, Thomas J. Slaga, Zbigniew Walaszek
Pages: 911-918
Published online on: 05 July 2013

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Article

Sequential use of protein kinase inhibitors potentiates their toxicity to melanoma cells: A rationale to combine targeted drugs based on protein expression inhibition profiles Retraction in /10.3892/ijo.2024.5707

Philippe G. Aftimos, Murielle Wiedig, Mireille Langouo Fontsa, Ahmad Awada, Ghanem Ghanem, Fabrice Journe
Pages: 919-926
Published online on: 08 July 2013

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Article

Inhibition of late-stage autophagy synergistically enhances pyrrolo-1,5-benzoxazepine-6-induced apoptotic cell death in human colon cancer cells

Lisa M. Greene, Derek P. Nolan, Daniel Regan-Komito, Giuseppe Campiani, D. Clive Williams, Daniela M. Zisterer
Pages: 927-935
Published online on: 25 June 2013

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Article

Anti-apoptotic proteins and catalase-dependent apoptosis resistance in nickel chloride-transformed human lung epithelial cells

Yu-Xiu Yang, Xiu-Ling Li, Lei Wang, Shuang-Yin Han, Yan-Rui Zhang, Poyil Pratheeshkumar, Xin Wang, Jian Lu, Yuan-Qin Yin, Li-Juan Sun, Amit Budhraja, Andrew J. Hitron, Song-Ze Ding
Pages: 936-946
Published online on: 03 July 2013

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Article

Polyphenols with indirect proprotein convertase inhibitory activity

Jingjing Zhu, Wim Van de Ven, Alphons Vermorken
Pages: 947-955
Published online on: 08 July 2013

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Article

Antioxidant extracts of African medicinal plants induce cell cycle arrest and differentiation in B16F10 melanoma cells

Angelo Gismondi, Lorena Canuti, Stefania Impei, Gabriele Di Marco, Maurice Kenzo, Vittorio Colizzi, Antonella Canini
Pages: 956-964
Published online on: 01 July 2013

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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