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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2015 Volume 47 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

The collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review)

Maria C. Melander, Henrik J. Jürgensen, Daniel H. Madsen, Lars H. Engelholm, Niels Behrendt
Pages: 1177-1188
Published online on: 12 August 2015

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Review Open Access

Deficient mismatch repair: Read all about it (Review)

Susan Richman
Pages: 1189-1202
Published online on: 12 August 2015

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Review Open Access

Emerging roles of microRNAs in pancreatic cancer diagnosis, therapy and prognosis (Review)

Ramadevi Subramani, Laxman Gangwani, Sushmita Bose Nandy, Arunkumar Arumugam, Munmun Chattopadhyay, Rajkumar Lakshmanaswamy
Pages: 1203-1210
Published online on: 21 August 2015

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Review Open Access

The cnidarian origin of the proto-oncogenes NF-κB/STAT and WNT-like oncogenic pathway drives the ctenophores (Review)

Joseph G. Sinkovics
Pages: 1211-1229
Published online on: 23 July 2015

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Article Open Access

FOXM1 is overexpressed in B-acute lymphoblastic leukemia (B-ALL) and its inhibition sensitizes B-ALL cells to chemotherapeutic drugs

Francesca Consolaro, Giuseppe Basso, Sadaf Ghaem-Magami, Eric W.-F. Lam, Giampietro Viola
Pages: 1230-1240
Published online on: 28 August 2015

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Article Open Access

Zn(II)-curc targets p53 in thyroid cancer cells

Alessia Garufi, Valerio D'Orazi, Alessandra Crispini, Gabriella D'Orazi
Pages: 1241-1248
Published online on: 13 August 2015

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Article Open Access

MicroRNA expression profiles of cancer stem cells in head and neck squamous cell carcinoma

Kazuya Yata, Levent Bekir Beder, Shunji Tamagawa, Muneki Hotomi, Yoshihiko Hirohashi, Reidar Grenman, Noboru Yamanaka
Pages: 1249-1256
Published online on: 31 August 2015

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Article Open Access

Podophyllotoxin acetate triggers anticancer effects against non-small cell lung cancer cells by promoting cell death via cell cycle arrest, ER stress and autophagy

Jae Yeon Choi, Wan Gi Hong, Jeong Hyun Cho, Eun Mi Kim, Jongdoo Kim, Chan-Hun Jung, Sang-Gu Hwang, Hong-Duck Um, Jong Kuk Park
Pages: 1257-1265
Published online on: 13 August 2015

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Article Open Access

Novel therapy for locally advanced triple-negative breast cancer

Atsuko Yamada, Shinji Osada, Toshiyuki Tanahashi, Satoshi Matsui, Yoshiyuki Sasaki, Yoshihiro Tanaka, Naoki Okumura, Nobuhisa Matsuhashi, Takao Takahashi, Kazuya Yamaguchi, Kazuhiro Yoshida
Pages: 1266-1272
Published online on: 05 August 2015

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Article

Identification of Akt1 as a potent therapeutic target for oral squamous cell carcinoma Corrigendum in /10.3892/ijo.2025.5790

Koh-Ichi Nakashiro, Hiroshi Tanaka, Hiroyuki Goda, Kazuki Iwamoto, Norihiko Tokuzen, Shingo Hara, Jun Onodera, Ichiro Fujimoto, Satoshi Hino, Hiroyuki Hamakawa
Pages: 1273-1281
Published online on: 25 August 2015

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Article

Expression profile of parkin isoforms in human gliomas

Grazia Maugeri, Agata Grazia D'Amico, Gaetano Magro, Lucia Salvatorelli, Giuseppe M.V. Barbagallo, Salvatore Saccone, Filippo Drago, Sebastiano Cavallaro, Velia D'Agata
Pages: 1282-1292
Published online on: 24 July 2015

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Article

Mechanism of gemcitabine-induced suppression of human cholangiocellular carcinoma cell growth

Yuka Toyota, Hisakazu Iwama, Kiyohito Kato, Joji Tani, Akiko Katsura, Miwa Miyata, Shintaro Fujiwara, Koji Fujita, Teppei Sakamoto, Takayuki Fujimori, Ryoichi Okura, Kiyoyuki Kobayashi, Tomoko Tadokoro, Shima Mimura, Takako Nomura, Hisaaki Miyoshi, Asahiro Morishita, Hideki Kamada, Hirohito Yoneyama, Keiichi Okano, Yasuyuki Suzuki, Tsutomu Masaki
Pages: 1293-1302
Published online on: 07 August 2015

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Article

Cyanidin induces apoptosis and differentiation in prostate cancer cells

Valeria Sorrenti, Luca Vanella, Rosaria Acquaviva, Venera Cardile, Salvatore Giofrè, Claudia Di Giacomo
Pages: 1303-1310
Published online on: 24 August 2015

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Article

HER4 tumor expression in breast cancer patients randomized to treatment with or without tamoxifen

Anna Göthlin Eremo, Elisabet Tina, Pia Wegman, Olle Stål, Karin Fransén, Tommy Fornander, Sten Wingren
Pages: 1311-1320
Published online on: 28 July 2015

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Article

Atg5 siRNA inhibits autophagy and enhances norcantharidin-induced apoptosis in hepatocellular carcinoma

Xuanxuan Xiong, Mingbo Wu, Haiyan Zhang, Jin Li, Bo Lu, Yonggao Guo, Tian Zhou, Hao Guo, Rui Peng, Xiangcheng Li, Qingzhong Tian, Yun Wang
Pages: 1321-1328
Published online on: 24 July 2015

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Article

Increased urothelial cancer associated 1 is associated with tumor proliferation and metastasis and predicts poor prognosis in colorectal cancer

Beibei Ni, Xihu Yu, Xiaoyan Guo, Xinjuan Fan, Zihuan Yang, Peihuang Wu, Zixu Yuan, Yanhong Deng, Jianping Wang, Dianke Chen, Lei Wang
Pages: 1329-1338
Published online on: 29 July 2015

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Article

MicroRNA-34a regulates epithelial-mesenchymal transition and cancer stem cell phenotype of head and neck squamous cell carcinoma in vitro

Zhifeng Sun, Weiming Hu, Jinfeng Xu, Andreas M. Kaufmann, Andreas E. Albers
Pages: 1339-1350
Published online on: 31 August 2015

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Article

MicroRNA-24 upregulation inhibits proliferation, metastasis and induces apoptosis in bladder cancer cells by targeting CARMA3 Retraction in /10.3892/ijo.2023.5515

Shufang Zhang, Chong Zhang, Wei Liu, Wenwen Zheng, Yingai Zhang, Shunlan Wang, Denggao Huang, Xi Liu, Zhiming Bai
Pages: 1351-1360
Published online on: 07 August 2015

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Article

Vasoactive intestinal peptide represses activation of tumor-associated macrophages in gastric cancer via regulation of TNFα, IL-6, IL-12 and iNOS

Lu Chen, Weijie Yuan, Zhikang Chen, Shaobin Wu, Jie Ge, Jinxiang Chen, Zihua Chen
Pages: 1361-1370
Published online on: 19 August 2015

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Article

Characterization of PI (breast cancer cell special peptide) in MDA-MB-231 breast cancer cells and its potential therapeutic applications

Change Gao, Min Hong, Jiwei Geng, Huahua Zhou, Jian Dong
Pages: 1371-1378
Published online on: 31 August 2015

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Article

MicroRNA-181a regulates epithelial-mesenchymal transition by targeting PTEN in drug-resistant lung adenocarcinoma cells Retraction in /10.3892/ijo.2025.5784

Haihui Li, Pei Zhang, Xiaojin Sun, Yiming Sun, Chao Shi, Hao Liu, Xuegang Liu
Pages: 1379-1392
Published online on: 31 August 2015

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Article

Multifaceted roles of 5'-regulatory region of the cancer associated gene B4GALT1 and its comparison with the gene family

Mohammed A. Ibrahim Al-Obaide, Hytham Alobydi, Abdelsalam G. Abdelsalam, Ruiwen Zhang, Kalkunte S. Srivenugopal
Pages: 1393-1404
Published online on: 27 August 2015

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Article

Prognostic value and characterization of the ovarian cancer-specific antigen CA166-9

Fangxing Ji, Xiaohong Chang, Caiyun Liu, Lin Meng, Like Qu, Jian Wu, Chanzhen Liu, Heng Cui, Chengchao Shou
Pages: 1405-1415
Published online on: 06 August 2015

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Article

Impact of Helicobacter pylori on the growth of hepatic orthotopic graft tumors in mice

Junwei Wang, Xiaoqian Wang, Nanhong Tang, Yanling Chen, Feifei She
Pages: 1416-1428
Published online on: 28 July 2015

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Article

Metastasis suppressor 1 expression in human ovarian cancer: The impact on cellular migration and metastasis Corrigendum in /10.3892/ijo.2025.5770

Rong Liu, Tracey A. Martin, Nicola J. Jordan, Fiona Ruge, Lin Ye, Wen G. Jiang
Pages: 1429-1439
Published online on: 13 August 2015

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Article

Mechanisms for SU5416 as a radiosensitizer of endothelial cells

Eun Ho Kim, Mi-Sook Kim, Youn Kyoung Jeong, Ilsung Cho, Seung Hoon You, Sung Ho Cho, Hanna Lee, Won-Gyun Jung, Hag Dong Kim, Joon Kim
Pages: 1440-1450
Published online on: 21 August 2015

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Article

Interleukin-6 expression by interactions between gynecologic cancer cells and human mesenchymal stem cells promotes epithelial-mesenchymal transition

Kyeong A So, Kyung Jin Min, Jin Hwa Hong, Jae-Kwan Lee
Pages: 1451-1459
Published online on: 13 August 2015

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Article

Resveratrol enhanced anticancer effects of cisplatin on non-small cell lung cancer cell lines by inducing mitochondrial dysfunction and cell apoptosis

Lijie Ma, Wangping Li, Ruixuan Wang, Yandong Nan, Qingwei Wang, Wei Liu, Faguang Jin
Pages: 1460-1468
Published online on: 13 August 2015

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Article

DNA-hypomethylating agent, 5'-azacytidine, induces cyclooxygenase-2 expression via the PI3-kinase/Akt and extracellular signal-regulated kinase-1/2 pathways in human HT1080 fibrosarcoma cells

Seon-Mi Yu, Song-Ja Kim
Pages: 1469-1475
Published online on: 31 July 2015

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Article

Inhibition of CD147 expression by RNA interference reduces proliferation, invasion and increases chemosensitivity in cancer stem cell-like HT-29 cells

Jie Chen, Yuqin Pan, Bangshun He, Houqun Ying, Feng Wang, Huiling Sun, Qiwen Deng, Xian Liu, Kang Lin, Hongxin Peng, William C. Cho, Shukui Wang
Pages: 1476-1484
Published online on: 27 August 2015

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Article

A homogeneous time-resolved fluorescence-based high-throughput screening for discovery of inhibitors of Nef-sdAb19 interaction

Xiaoqin Fan, Jinmei Wei, Haiting Xiong, Xiaohui Liu, Serge Benichou, Xuejuan Gao, Langxia Liu
Pages: 1485-1493
Published online on: 25 August 2015

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Article

Myricetin inhibits proliferation of cisplatin-resistant cancer cells through a p53-dependent apoptotic pathway

Haizhi Huang, Allen Y. Chen, Xingqian Ye, Bingyun Li, Yon Rojanasakul, Gary O. Rankin, Yi Charlie Chen
Pages: 1494-1502
Published online on: 25 August 2015

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Article

HMGN5 blockade by siRNA enhances apoptosis, suppresses invasion and increases chemosensitivity to temozolomide in meningiomas

Jing He, Chaoyang Liu, Bin Wang, Na Li, Guoqin Zuo, Dewei Gao
Pages: 1503-1511
Published online on: 25 August 2015

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Article

Should a standard lymphadenectomy during pancreatoduodenectomy exclude para-aortic lymph nodes for all cases of resectable pancreatic head cancer? A consensus statement by the Chinese Study Group for Pancreatic Cancer (CSPAC)

Chen Liu, Rufu Chen, Yingtai Chen, Deliang Fu, Defei Hong, Jihui Hao, Dawei Liu, Jiangtao Li, Shengping Li, Yixiong Li, Gang Mai, Yiping Mou, Quanxing Ni, Li Peng, Honggang Qian, Renyi Qin, Bei Sun, Chenghao Shao, Yongwei Sun, Bole Tian, Jian Wang, Wei Wang, Weilin Wang, Gang Zhao, Xianjun Yu
Pages: 1512-1516
Published online on: 21 August 2015

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Article

E-cadherin knockdown increases β-catenin reducing colorectal cancer chemosensitivity only in three-dimensional cultures

Xi Liang, Xueqing Xu, Fengchao Wang, Xuedan Chen, Ni Li, Cancan Wang, Jianming He
Pages: 1517-1527
Published online on: 27 August 2015

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Article

miRNA-99b-3p functions as a potential tumor suppressor by targeting glycogen synthase kinase-3β in oral squamous cell carcinoma Tca-8113 cells

Kang He, Dongdong Tong, Si Zhang, Donghui Cai, Lumin Wang, Yang Yang, Ling Gao, Su'e Chang, Bo Guo, Tusheng Song, Ang Li, Chen Huang
Pages: 1528-1536
Published online on: 27 August 2015

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Article

Prospective evaluation of C-reactive protein, smoking and lung cancer death in the Third National Health and Nutrition Examination Survey

Marisa A. Bittoni, Brian C. Focht, Steven K. Clinton, Janet Buckworth, Randall E. Harris
Pages: 1537-1544
Published online on: 31 August 2015

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Article

MicroRNA-146a inhibits epithelial mesenchymal transition in non-small cell lung cancer by targeting insulin receptor substrate 2

Dong Ho Park, Hyo Sung Jeon, Soo Young Lee, Yi Young Choi, Hae Woo Lee, Seongkyu Yoon, Jae Chel Lee, Yoo Sang Yoon, Dae Sung Kim, Moon Jun Na, Sun Jung Kwon, Dong Sun Kim, Jaeku Kang, Jae Yong Park, Ji Woong Son
Pages: 1545-1553
Published online on: 04 August 2015

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Article

Identification of a non-coding KLF4 transcript generated from intron retention and downregulated in human hepatocellular carcinoma

Junwei Zhou, Paul Bo-San Lai, Stephen Kwok-Wing Tsui
Pages: 1554-1562
Published online on: 24 July 2015

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Article

The flavonoid p-hydroxycinnamic acid mediates anticancer effects on MDA-MB-231 human breast cancer cells in vitro: Implications for suppression of bone metastases

Masayoshi Yamaguchi, Tomiyasu Murata, Mamoru Shoji, M. Neale Weitzmann
Pages: 1563-1571
Published online on: 28 July 2015

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Article

Downregulation of BCRP and anti-apoptotic proteins by proadifen (SKF-525A) is responsible for the enhanced mitoxantrone accumulation and toxicity in mitoxantrone-resistant human promyelocytic leukemia cells

Lucia Hiľovská, Rastislav Jendželovský, Zuzana Jendželovská, Ján Kovaľ, Peter Fedoročko
Pages: 1572-1584
Published online on: 06 August 2015

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Article

miR-132 inhibits cell proliferation, invasion and migration of hepatocellular carcinoma by targeting PIK3R3 Retraction in /10.3892/ijo.2021.5238

Kai Liu, Xingliang Li, Yuchen Cao, Yuanyuan Ge, Jianmeng Wang, Bo Shi
Pages: 1585-1593
Published online on: 04 August 2015

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Article

MicroRNA-338-3p functions as tumor suppressor in breast cancer by targeting SOX4 Retraction in /10.3892/ijo.2024.5609

Ying Jin, Min Zhao, Qian Xie, Hongyan Zhang, Qing Wang, Qingjie Ma
Pages: 1594-1602
Published online on: 06 August 2015

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Article

miR-873 acts as a novel sensitizer of glioma cells to cisplatin by targeting Bcl-2

Xiong Chen, Yingying Zhang, Yingying Shi, Haiwei Lian, Huilin Tu, Song Han, Biwen Peng, Wanhong Liu, Xiaohua He
Pages: 1603-1611
Published online on: 31 August 2015

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Journal Cover
March-2026 Volume 68 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Circ72309 modulates gemcitabine metabolism and gemcitabine sensitivity in pancreatic cancer: Serum Circ72309 levels as a potential predictor of treatment response

Naoko Sekiguchi, Hidenori Takahashi, Shogo Kobayashi, Kazuki Sasaki, Shinichiro Hasegawa, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Hirofumi Akita, Tadafumi Asaoka, Takehiro Noda, Junzo Shimizu, Koji Tanaka, Ryota Chijimatsu, Yuichiro Doki, Hidetoshi Eguchi
Article Number: 36
Published online on: 16 January 2026

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Review Open Access

Unveiling sex differences in pancreatic ductal adenocarcinoma: Current evidence and future directions (Review)

Sophie Rauschenberg, Elisabeth Orgler‑Gasche, Didem Karakas Zeybek, Ivonne Regel, J.-Matthias Löhr, Daniel Öhlund, Michael Günther, Lina Aguilera Munoz
Article Number: 35
Published online on: 15 January 2026

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Retraction Open Access

[Retracted] LTBP2 promotes the migration and invasion of gastric cancer cells and predicts poor outcome of patients with gastric cancer

Jun Wang, Wen-Jia Liang, Guang-Tao Min, Hong-Peng Wang, Wei Chen, Nan Yao
Article Number: 34
Published online on: 13 January 2026

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Article Open Access

KMO downregulation promotes hepatocellular carcinoma growth via 3‑HAA‑mediated mitochondrial mass and function imbalances

Ming Liu, Xintong Zhang, Yanfen Hu, Li Niu, Linzhi Guo, Guoqing Zhao, Fan Lu, Fengfeng Jia, Li Li, Hao Wu, Jianjun Zhu
Article Number: 33
Published online on: 13 January 2026

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Review Open Access

Regulatory networks of HIFs in tumor‑infiltrating immune cells: From molecular mechanisms to therapeutic implications (Review)

Chaoqun Li, Chenge Qin, Xingchen Li, Jinzhu Wang, Yang Li, Qin Sun
Article Number: 32
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] uPAR and cathepsin B knockdown inhibits radiation‑induced PKC integrated integrin signaling to the cytoskeleton of glioma‑initiating cells

Kiranmai Alapati, Sreelatha Gopinath, Rama Rao Malla, Venkata Ramesh Dasari, Jasti S. Rao
Article Number: 31
Published online on: 05 January 2026

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Article Open Access

PTPN18 functions as a tumor suppressor in breast cancer by negatively regulating cyclin E

Na Zhang, Tao Wang, Bin Bai, Xiaonan Zhang, Wenying Xu, Weilu Chen, Yang Yu, Bing Wang
Article Number: 30
Published online on: 30 December 2025

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Retraction Open Access

[Retracted] Suppression of the death gene BIK is a critical factor for resistance to tamoxifen in MCF‑7 breast cancer cells

Rubí Viedma-Rodriguez, Luis Arturo Baiza-Gutman, Alejandro García-Carrancá, Leticia Moreno-Fierros, Fabio Salamanca-Gómez, Diego Arenas-Aranda
Article Number: 29
Published online on: 23 December 2025

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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