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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2008 Volume 19 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Effect of combining anti-epidermal growth factor receptor antibody C225 and radiation on DU145 prostate cancer

Matthew Wagener, Xiaochun Zhang, Humberto G. Villarreal, Larry Levy, Pamela Allen, Shujun Shentu, Bingliang Fang, Sunil Krishnan, Joe Y. Chang, M. Rex Cheung
Pages: 1071-1077
Published online on: 01 May 2008

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Article

Involvement of EphA2 in head and neck squamous cell carcinoma: mRNA expression, loss of heterozygosity and immunohistochemical studies

Rosario S. Rivera, Mehmet Gunduz, Hitoshi Nagatsuka, Esra Gunduz, Beyhan Cengiz, Kunihiro Fukushima, Levent Bekir Beder, Davut Pehlivan, Noboru Yamanaka, Kenji Shimizu, Noriyuki Nagai
Pages: 1079-1084
Published online on: 01 May 2008

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Article

Secretory leukoprotease inhibitor inhibits cell growth through apoptotic pathway on ovarian cancer

Keiichiro Nakamura, Norio Takamoto, Atsushi Hongo, Junichi Kodama, Fernando Abrzua, Yasutomo Nasu, Hiromi Kumon, Yuji Hiramatsu
Pages: 1085-1091
Published online on: 01 May 2008

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Article

Expression of E1AF, an ets-oncogene transcription factor, highly correlates with malignant phenotype of malignant melanoma through up-regulation of the membrane-type-1 matrix metalloproteinase gene

Hironobu Hata, Tetsuya Kitamura, Fumihiro Higashino, Kyoko Hida, Koichi Yoshida, Yoichi Ohiro, Yasunori Totsuka, Yoshimasa Kitagawa, Masanobu Shindoh
Pages: 1093-1098
Published online on: 01 May 2008

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Article

The activation of Akt during preoperative chemotherapy for esophageal cancer correlates with poor prognosis

Akiko Yoshioka, Hiroshi Miyata, Yuichiro Doki, Takushi Yasuda, Makoto Yamasaki, Masaaki Motoori, Kazuyuki Okada, Jin Matsuyama, Youichi Makari, Itsuro Sohma, Shuji Takiguchi, Yoshiyuki Fujiwara, Morito Monden
Pages: 1099-1107
Published online on: 01 May 2008

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Article

Clodronate inhibits angiogenesis in vitro and in vivo

D. Ribatti, N. Maruotti, B. Nico, V. Longo, D. Mangieri, A. Vacca, F. P. Cantatore
Pages: 1109-1112
Published online on: 01 May 2008

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Article

Formoterol fumarate and roxithromycin effects on muscle mass in an animal model of cancer cachexia

Richard A. Kenley, Mikhail F. Denissenko, Robert J. Mullin, Jennifer Story, Jonas Ekblom
Pages: 1113-1121
Published online on: 01 May 2008

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Article

Irinotecan HCl, an anticancer topoisomerase I inhibitor, frequently induces ovarian failure in premenopausal and perimenopausal women

Tetsuji Tanaka, Tomoko Utsunomiya, Hirotoshi Utsunomiya, Naohiko Umesaki
Pages: 1123-1133
Published online on: 01 May 2008

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Article

Improved detection of hepatic metastases of adrenocortical cancer by contrast-enhanced ultrasound

Juergen Bauditz, Marcus Quinkler, Dirk Beyersdorff, Wolfram Wermke
Pages: 1135-1139
Published online on: 01 May 2008

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Article

PTEN and p27Kip1 are not downregulated in the majority of renal cell carcinomas - implications for Akt activation

Joerg Hennenlotter, Petra A. Ohneseit, Perikles Simon, Axel S. Merseburger, Juergen Serth, Ursula Kuehs, Mario Kramer, Joerg T. Hartmann, Arnulf Stenzl, Markus A. Kuczyk
Pages: 1141-1147
Published online on: 01 May 2008

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Article

Expression and promoter methylation of the RASSF1A gene in sporadic breast cancers in Chinese women

Yongmei Li, Qinjun Wei, Fang Cao, Xin Cao
Pages: 1149-1153
Published online on: 01 May 2008

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Article

1p31, 7q21 and 18q21 chromosomal aberrations and candidate genes in acquired vinblastine resistance of human cervical carcinoma KB cells

Jin Wang, Lai-Shan Tai, Chi-Hung Tzang, Wan Fong Fong, Xin-Yuan Guan, Mengsu Yang
Pages: 1155-1164
Published online on: 01 May 2008

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Article

Sodium salicylate switches glucose depletion-induced necrosis to autophagy and inhibits high mobility group box protein 1 release in A549 lung adenocarcinoma cells

Sung-Chul Lim, Sun Mi Kim, Jeong Eun Choi, Cho Hee Kim, Hong-Quan Duong, Song Iy Han, Ho Sung Kang
Pages: 1165-1171
Published online on: 01 May 2008

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Article

Interleukin 15 augments antitumor activity of cytokine gene-modified melanoma cell vaccines in a murine model

Grzegorz W. Basak, Lukasz Zapala, Piotr J. Wysocki, Andrzej Mackiewicz, Marek Jakóbisiak, Witold Lasek
Pages: 1173-1179
Published online on: 01 May 2008

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Article

A dual colour dual fusion fluorescence in situ hybridisation study on the genesis of complex variant translocations in chronic myelogenous leukaemia

Chi-Chiu So, Thomas Shek-Kong Wan, Sze-Fai Yip, Li-Chong Chan
Pages: 1181-1184
Published online on: 01 May 2008

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Article

Expression of Sonic hedgehog signaling pathway correlates with the tumorigenesis of intraductal papillary mucinous neoplasm of the pancreas

Kennichi Satoh, Atsushi Kanno, Shin Hamada, Morihisa Hirota, Jun Umino, Atsushi Masamune, Shinichi Egawa, Fuyuhiko Motoi, Michiaki Unno, Tooru Shimosegawa
Pages: 1185-1190
Published online on: 01 May 2008

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Article

New insight into the key proteins and pathways involved in the metastasis of colorectal carcinoma

Guan-Zhen Yu, Ying Chen, Ya-Qiu Long, Dong Dong, Xiao-Lan Mu, Jie-Jun Wang
Pages: 1191-1204
Published online on: 01 May 2008

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Article

Lovastatin enhances the antitumoral and apoptotic activity of doxorubicin in murine tumor models

Viviana R. Rozados, Lucila I. Hinrichsen, M. Mercedes Binda, Silvia I. Gervasoni, Pablo Matar, R. Daniel Bonfil, O. Graciela Scharovsky
Pages: 1205-1211
Published online on: 01 May 2008

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Article

First genetic analysis in Tunisian familial adenomatous polyposis probands

Karim Bougatef, Raja Marrakchi, Amel Moussa, Yannick Blondeau-Lahely, Tawfik Najjar, Florence Coulet, Chrystelle Colas, Farhat Ben Ayed, Amel Ben Ammar Elgaaied, Florent Soubrier
Pages: 1213-1218
Published online on: 01 May 2008

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Article

Intracavitary chemotherapy (Gliadel®) and oral low-dose etoposide for recurrent anaplastic ependymoma

Iacopo Sardi, Massimiliano Sanzo, Flavio Giordano, Alessandro Sandri, Federico Mussa, Pier A. Donati, Lorenzo Genitori
Pages: 1219-1223
Published online on: 01 May 2008

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Article

Inhibition of NADPH oxidase activity promotes differentiation of B16 melanoma cells

Yunfeng Zhao, Jianfeng Liu, Kenneth E. McMartin
Pages: 1225-1230
Published online on: 01 May 2008

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Article

Genistein differentially modulates androgen-responsive gene expression and activates JNK in LNCaP cells

Bato Lazarevic, Steinar Johan Karlsen, Fahri Saatcioglu
Pages: 1231-1235
Published online on: 01 May 2008

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Article

2-DE analysis of breast cancer cell lines 1833 and 4175 with distinct metastatic organ-specific potentials: Comparison with parental cell line MDA-MB-231

Irena Selicharova, Miloslav Sanda, Jana Mladkova, Sujata Saraswat Ohri, Aruna Vashishta, Martin Fusek, Jiri Jiracek, Vaclav Vetvicka
Pages: 1237-1244
Published online on: 01 May 2008

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Article

Role of serum-derived hyaluronan-associated protein-hyaluronan complex in ovarian cancer

Yukihiko Obayashi, Hiromitsu Yabushita, Kouhei Kanyama, Mari Noguchi, Lisheng Zhuo, Koji Kimata, Akihiko Wakatsuki
Pages: 1245-1251
Published online on: 01 May 2008

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Article

Suppression of the proliferation of cancer cell lines, KB-3-1 and K562 cells preceded by a decrease in intracellular pH caused by phenoxazine derivatives

Xiao-Fang Che, Shin-Ichi Akiyama, Akio Tomoda
Pages: 1253-1258
Published online on: 01 May 2008

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Article

Survival analysis of ovarian clear cell carcinoma confined to the ovary with or without comprehensive surgical staging

Masashi Takano, Naoki Sasaki, Tsunekazu Kita, Kazuya Kudoh, Kazuyuki Fujii, Tomoyuki Yoshikawa, Masafumi Kato, Junko Hirata, Kenichi Furuya, Hitoshi Tsuda, Yoshihiro Kikuchi
Pages: 1259-1264
Published online on: 01 May 2008

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Article

Combinations of tumor-specific CD8+ CTLs and anti-CD25 mAb provide improved immunotherapy

Yukinobu Ohmura, Kazuhiro Yoshikawa, Shinsuke Saga, Ryuzo Ueda, Yoshiaki Kazaoka, Shiro Yamada
Pages: 1265-1270
Published online on: 01 May 2008

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Article

Fluorescent in situ hybridization as a screening test for HER2 amplification in G2 and G3 breast cancers of lobular and ductal histotype and metastases

Isabella Castellano, Anna Sapino, Riccardo Arisio, Giuseppe Viale, Gianni Bussolati, Roberto Bandelloni, Gaetano Barresi, Alessandra Bersiga, Cesare Bordi, Gerardo Botti, Fabia Cosimi, Emanuele D'Amore, Claudio Doglioni, Antonio Marchetti, Oscar Nappi, Francesco Romeo, Massimo Roncalli, Rosa Russo, Alfredo Santinelli, Luigi Giusto Spagnoli, Francesco Tanda, Paolo Tricomi, Gianpaolo Trentini, Fabrizio Zanconati, Monica Iurlaro
Pages: 1271-1275
Published online on: 01 May 2008

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Article

Identification of EphB6 variant-derived epitope peptides recognized by cytotoxic T-lymphocytes from HLA-A24+ malignant glioma patients

Mingyue Jin, Yoshihiro Komohara, Shigeki Shichijo, Mamoru Harada, Ryuya Yamanaka, Shigeaki Miyamoto, Junichi Nikawa, Kyogo Itoh, Akira Yamada
Pages: 1277-1283
Published online on: 01 May 2008

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Article

Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from colorectal cancer

Takashi Oshima, Chikara Kunisaki, Kazue Yoshihara, Roppei Yamada, Naoto Yamamoto, Tsutomu Sato, Hirochika Makino, Shigeru Yamagishi, Yasuhiko Nagano, Shoich Fujii, Manabu Shiozawa, Makoto Akaike, Nobuyuki Wada, Yasushi Rino, Munetaka Masuda, Katsuaki Tanaka, Toshio Imada
Pages: 1285-1291
Published online on: 01 May 2008

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Article

Alterations of the K-ras and p53 genes in Tamoxifen-associated endometrial carcinoma

Kazuko Fujiwara, Takayuki Enomoto, Masami Fujita, Takayoshi Kanda, Shingo Fujii, Kimihiko Ito, Kenichi Wakasa, Osamu Ishiko, Masatsugu Ueda, Satoshi Yamaguchi, Tadashi Kimura, Naohiko Umesaki
Pages: 1293-1298
Published online on: 01 May 2008

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Article

Perforating branches of the internal thoracic artery in women with breast cancer: An anatomical study for breast-conservation surgery

Kimiko Nakatani, Hironori Maeda, Yousuke Tanaka, Norihiko Hamada, Akihito Nishioka, Shiro Sasaguri, Yasuhiro Ogawa
Pages: 1299-1303
Published online on: 01 May 2008

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Article

Dual anti-cancer effects of weekly intraperitoneal docetaxel in treatment of advanced gastric cancer patients with peritoneal carcinomatosis: A feasibility and pharmacokinetic study

Sachio Fushida, Jun Kinoshita, Yasumichi Yagi, Hiroshi Funaki, Shinichi Kinami, Itasu Ninomiya, Takashi Fujimura, Genichi Nishimura, Masato Kayahara, Tetsuo Ohta
Pages: 1305-1310
Published online on: 01 May 2008

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Article

Polymorphisms in CYP1B1, GSTM1, GSTT1 and GSTP1, and susceptibility to breast cancer

Beth O. Van Emburgh, Jennifer J. Hu, Edward A. Levine, Libyadda J. Mosley, Nancy D. Perrier, Rita I. Freimanis, Glenn O. Allen, Peter Rubin, Gary B. Sherrill, Cindy S. Shaw, Lisa A. Carey, Lynda R. Sawyer, Mark Steven Miller
Pages: 1311-1321
Published online on: 01 May 2008

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Article

Transient suppression of nuclear Cdc2 activity in response to ionizing radiation

Min-Jung Kim, Jeong-Yim Lee, Su-Jae Lee
Pages: 1323-1329
Published online on: 01 May 2008

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Article

The role of nitric oxide on DNA damage induced by benzene metabolites

Assieh A. Melikian, Kun-Ming Chen, Heyi Li, Rama Sodum, Emerich Fiala, Karam El-Bayoumy
Pages: 1331-1337
Published online on: 01 May 2008

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Article

Promoter methylation of death-associated protein kinase and its role in irradiation response in cervical cancer Expression of Concern in /10.3892/or.2025.9028

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Pages: 1339-1345
Published online on: 01 May 2008

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Article

Her-2/neu amplification and breast cancer survival: Results from the Shanghai breast cancer study

Alicia Beeghly-Fadiel, Nobuhiko Kataoka, Xiao-Ou Shu, Qiuyin Cai, Sandra L. Deming, Yu-Tang Gao, Wei Zheng
Pages: 1347-1354
Published online on: 01 May 2008

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Article

Adjuvant chemotherapy with tegafur/uracil administration after transcatheter arterial chemoembolization for advanced hepatocellular carcinoma

Hiroki Ueda, Hiroto Tanaka, Yohei Kida, Hiroko Fukuchi, Masakazu Ichinose
Pages: 1355-1361
Published online on: 01 May 2008

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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April-2026 Volume 55 Issue 4

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Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

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