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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2008 Volume 20 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Glutathione peroxidase 3 is a candidate mechanism of anticancer drug resistance of ovarian clear cell adenocarcinoma

Yasushi Saga, Michitaka Ohwada, Mitsuaki Suzuki, Ryo Konno, Junzo Kigawa, Shuichi Ueno, Hiroyuki Mano
Pages: 1299-1303
Published online on: 01 December 2008

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Article

Clinical responses in patients with advanced colorectal cancer to a dendritic cell based vaccine

Stefan K. Burgdorf, Anders Fischer, Peter S. Myschetzky, Signe B. Munksgaard, Mai-Britt Zocca, Mogens H. Claesson, Jacob Rosenberg
Pages: 1305-1311
Published online on: 01 December 2008

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Article

Clinical significance of ApoE expression in human gastric cancer

Katsuya Sakashita, Fumiaki Tanaka, Xiang Zhang, Koshi Mimori, Yukio Kamohara, Hiroshi Inoue, Tetsuji Sawada, Kosei Hirakawa, Masaki Mori
Pages: 1313-1319
Published online on: 01 December 2008

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Article

Guggulsterone inhibits angiogenesis by blocking STAT3 and VEGF expression in colon cancer cells

Eun Soo Kim, Sung Yi Hong, Hye Kyung Lee, Seung Won Kim, Min Ji An, Tae Il Kim, Kyoung Ryul Lee, Won Ho Kim, Jae Hee Cheon
Pages: 1321-1327
Published online on: 01 December 2008

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Article

N-myc downstream regulated gene 1 (NDRG1)/Cap43 enhances portal vein invasion and intrahepatic metastasis in human hepatocellular carcinoma

Jun Akiba, Sachiko Ogasawara, Akihiko Kawahara, Naoyo Nishida, Sakiko Sanada, Fukuko Moriya, Michihiko Kuwano, Osamu Nakashima, Hirohisa Yano
Pages: 1329-1335
Published online on: 01 December 2008

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Article

ILK overexpression in human hepatocellular carcinoma and liver cirrhosis correlates with activation of Akt

Stavros Peroukides, Vasiliki Bravou, John Varakis, Alexandros Alexopoulos, Haralabos Kalofonos, Helen Papadaki
Pages: 1337-1344
Published online on: 01 December 2008

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Article

Targeting β1 integrin restores sensitivity to docetaxel of esophageal squamous cell carcinoma

Ryota Mori, Hideyuki Ishiguro, Yoshiyuki Kuwabara, Masahiro Kimura, Akira Mitsui, Keisuke Tomoda, Yoichiro Mori, Ryo Ogawa, Takeyasu Katada, Koshiro Harata, Yoshitaka Fujii
Pages: 1345-1351
Published online on: 01 December 2008

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Article

Inhibition of syndecan-1 expression and function in oral cancer cells

Takashi Muramatsu, Masato Saitoh, Yasufumi Ro, Tomoko Uekusa, Eri Iwamura, Kazumasa Ohta, Yohko Kohno, Yoshihiro Abiko, Masaki Shimono
Pages: 1353-1357
Published online on: 01 December 2008

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Article

Blazein of a new steroid isolated from Agaricus blazei Murrill (himematsutake) induces cell death and morphological change indicative of apoptotic chromatin condensation in human lung cancer LU99 and stomach cancer KATO III cells

Hiroko Itoh, Hitoshi Ito, Hiroshige Hibasami
Pages: 1359-1361
Published online on: 01 December 2008

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Article

Anti-tumor effects of telomelysin for head and neck squamous cell carcinoma

Kyoko Fujita, Machiko Kimura, Norio Kondo, Atsuko Sakakibara, Daisuke Sano, Yukari Ishiguro, Mamoru Tsukuda
Pages: 1363-1368
Published online on: 01 December 2008

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Article

Solid neuroendocrine breast carcinomas: Incidence, clinico-pathological features and immunohistochemical profiling

Eugeni López-Bonet, Miguel Alonso-Ruano, Graciela Barraza, Alejandro Vazquez-Martin, Luis Bernadó, Javier A. Menendez
Pages: 1369-1374
Published online on: 01 December 2008

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Article Open Access

Secretion of N-ERC/mesothelin and expression of C-ERC/mesothelin in human pancreatic ductal carcinoma

Koichi Inami, Kazunori Kajino, Masaaki Abe, Yoshiaki Hagiwara, Masahiro Maeda, Masafumi Suyama, Sumio Watanabe, Okio Hino
Pages: 1375-1380
Published online on: 01 December 2008

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Article

Expression of Glut-1 is a prognostic marker for oral squamous cell carcinoma patients

A. W. Eckert, M. H.W. Lautner, H. Taubert, J. Schubert, U. Bilkenroth
Pages: 1381-1385
Published online on: 01 December 2008

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Article

Glycyrrhizin induces apoptosis in prostate cancer cell lines DU-145 and LNCaP

Sivasakthivel Thirugnanam, Lipeng Xu, Kalyanasundaram Ramaswamy, Munirathinam Gnanasekar
Pages: 1387-1392
Published online on: 01 December 2008

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Article

Specific rearrangement of the microtubular network during the cell cycle phases and correlation with micronucleation and death induced by anticancer drugs in NIH/3T3 subcultures

Alessandra Spano, Gianni Monaco, Sergio Barni, Luigi Sciola
Pages: 1393-1402
Published online on: 01 December 2008

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Article

Decreased expression of galectin-3 predicts tumour recurrence in pTa bladder cancer

Mario Wolfgang Kramer, Markus Antonius Kuczyk, Jörg Hennenlotter, Jürgen Serth, David Schilling, Arnulf Stenzl, Axel Stuart Merseburger
Pages: 1403-1408
Published online on: 01 December 2008

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Article

Activation of mTOR in a subgroup of ovarian carcinomas: Correlation with p-eIF-4E and prognosis

Aurelia Noske, Juliane Lena Lindenberg, Silvia Darb-Esfahani, Wilko Weichert, Ann-Christin Buckendahl, Annika Röske, Jalid Sehouli, Manfred Dietel, Carsten Denkert
Pages: 1409-1417
Published online on: 01 December 2008

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Article

Evaluation of cytotoxic effects induced by bcl-2 and bcl-xL antisense-oligodeoxynucleotides in normal urothelium and transitional cell carcinoma

Ute Gabriel, Christian Bolenz, Andreas Becker, Axel Schaaf, Annette Steidler, Lutz Trojan, Christel Weiss, Maurice Stephan Michel
Pages: 1419-1423
Published online on: 01 December 2008

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Article

Stable suppression of HER-2 gene expression using siRNA increases the lysis of human ovarian carcinoma cells mediated by NK-92 cell line

Ying Zhou, Zhixiang Cheng, Huaiping Zhu, Dingqing Feng, Weidong Zhao, Bin Ling, Haiming Wei, Zhigang Tian
Pages: 1425-1431
Published online on: 01 December 2008

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Article

Specific reversal of MDR1/P-gp-dependent multidrug resistance by RNA interference in colon cancer cells

Zhongsheng Xia, Zhaohua Zhu, Liyong Zhang, Crista Royal, Zhongmin Liu, Qikui Chen, Bao-Ling Adam
Pages: 1433-1439
Published online on: 01 December 2008

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Article

Overexpression of insulin-like growth factor binding protein 3 in oral squamous cell carcinoma

Lai-Ping Zhong, Xiao Yang, Lei Zhang, Kui-Jie Wei, Hong-Ya Pan, Xiao-Jian Zhou, Jiang Li, Wan-Tao Chen, Zhi-Yuan Zhang
Pages: 1441-1447
Published online on: 01 December 2008

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Article

Soluble transforming growth factor β type II receptor attenuates TGF-β1 activity in human colorectal cancer LoVo cells

Rui Zhou, Bin Xiong, Haibin Song, Shiquan Liu, Xinbo Wang
Pages: 1449-1456
Published online on: 01 December 2008

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Article

Glioma cells enhance endothelial progenitor cell angiogenesis via VEGFR-2, not VEGFR-1

Junxia Zhang, Peng Zhao, Zhen Fu, Xiaolei Chen, Ning Liu, Ailin Lu, Rui Li, Lei Shi, Peiyu Pu, Chunsheng Kang, Yongping You
Pages: 1457-1463
Published online on: 01 December 2008

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Article

Survival advantages of multicellular spheroids vs. monolayers of HepG2 cells in vitro

Chun-Li Li, Tao Tian, Ke-Jun Nan, Na Zhao, Ya-Huan Guo, Jie Cui, Jin Wang, Wang-Gang Zhang
Pages: 1465-1471
Published online on: 01 December 2008

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Article

TAE226, a dual inhibitor for FAK and IGF-IR, has inhibitory effects on mTOR signaling in esophageal cancer cells

Zhi Gang Wang, Takuya Fukazawa, Toshio Nishikawa, Nobuyuki Watanabe, Kazufumi Sakurama, Takayuki Motoki, Munenori Takaoka, Shinji Hatakeyama, Osamu Omori, Toshiaki Ohara, Shunsuke Tanabe, Yasuhiro Fujiwara, Yasuhiro Shirakawa, Tomoki Yamatsuji, Noriaki Tanaka, Yoshio Naomoto
Pages: 1473-1477
Published online on: 01 December 2008

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Article

Inhibitory effect of green tea extract and (−)-epigallocatechin-3-gallate on mammalian thioredoxin reductase and HeLa cell viability

Yan Wang, Huihui Zhang, Arne Holmgren, Weixi Tian, Liangwei Zhong
Pages: 1479-1487
Published online on: 01 December 2008

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Article

Quantitative detection of TIMP-3 promoter hypermethylation and its prognostic significance in esophageal squamous cell carcinoma

Itasu Ninomiya, Kazuyuki Kawakami, Sachio Fushida, Takashi Fujimura, Hiroshi Funaki, Hiroyuki Takamura, Hirohisa Kitagawa, Hisatoshi Nakagawara, Hidehiro Tajima, Masato Kayahara, Tetsuo Ohta
Pages: 1489-1495
Published online on: 01 December 2008

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Article

Matrix metalloproteinase-1 is a crucial bone metastasis factor in a human breast cancer-derived highly invasive cell line

Noritaka Okuyama, Akihiko Matsumine, Rieko Kosugi, Hiroki Wakabayashi, Atsumasa Uchida
Pages: 1497-1504
Published online on: 01 December 2008

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Article

Fermented Noni Exudate (fNE): A mediator between immune system and anti-tumor activity

Jinhua Li, Sara L. Stickel, Hilary Bouton-Verville, Kelly E. Burgin, Xianzhong Yu, Desmond K.W. Wong, Thomas E. Wagner, Yanzhang Wei
Pages: 1505-1509
Published online on: 01 December 2008

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Article

Immunological stress in kidney cancer patients undergoing either open nephrectomy or nephron-sparing surgery: An immunophenotypic study of lymphocyte subpopulations and circulating dendritic cells

Camillo Porta, Lucia Bonomi, Beatrice Lillaz, Catherine Klersy, Ilaria Imarisio, Chiara Paglino, Bianca Rovati, Marco Danova, Elisa Ferraris, Mario Mensi, Bruno Rovereto
Pages: 1511-1519
Published online on: 01 December 2008

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Article

Comparison between intravenous and oral postoperative adjuvant immunochemotherapy in patients with stage III colorectal cancer

Isao Ito, Masaya Mukai, Hiromi Ninomiya, Kyoko Kishima, Kazutoshi Tsuchiya, Takayuki Tajima, Masato Nakamura, Hiroyasu Makuuchi
Pages: 1521-1526
Published online on: 01 December 2008

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Article

Increased growth factor expression after hepatic and pancreatic resection

Christoph Justinger, Christian Schlüter, Vilma Oliviera-Frick, Berit Kopp, Claudia Rubie, Martin K. Schilling
Pages: 1527-1531
Published online on: 01 December 2008

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Article

Concurrent chemobiotherapy with cisplatin, dacarbazine, decrescendo interleukin-2 and interferon α2b in patients with metastatic melanoma

Jair Bar, Rinat Yerushalmi, Roni Shapira-Frummer, Irena Kutchuk, Aaron Sulkes, Haim Gutman, Raphael Catane, Jacob Schachter
Pages: 1533-1538
Published online on: 01 December 2008

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Article

Circulating 25-hydroxyvitamin D concentration in German cancer patients

Uwe Reinhold, Barbara Schmitz, Christian Kurbacher, Wolfgang Nagel, Matthias Schmidt, Willy J. Malaisse
Pages: 1539-1543
Published online on: 01 December 2008

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Article

Decreased orotate phosphoribosyltransferase activity produces 5-fluorouracil resistance in a human gastric cancer cell line

Yasuhiro Tsutani, Kazuhiro Yoshida, Yuichi Sanada, Yoshiyuki Wada, Kazuo Konishi, Masakazu Fukushima, Morihito Okada
Pages: 1545-1551
Published online on: 01 December 2008

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Article

AMPK mediates curcumin-induced cell death in CaOV3 ovarian cancer cells

Wei Pan, Hui Yang, Cong Cao, Xiuzu Song, Brittany Wallin, Rebecca Kivlin, Shan Lu, Gang Hu, Wen Di, Yinsheng Wan
Pages: 1553-1559
Published online on: 01 December 2008

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Article

Analysis of hypoxia-associated gene expression in prostate cancer: lysyl oxidase and glucose transporter-1 expression correlate with Gleason score

Grant D. Stewart, Kelly Gray, Caroline J. Pennington, Dylan R. Edwards, Antony C.P. Riddick, James A. Ross, Fouad K. Habib
Pages: 1561-1567
Published online on: 01 December 2008

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Article

EGF stimulates uPAR expression and cell invasiveness through ERK, AP-1, and NF-κB signaling in human gastric carcinoma cells

Min K. Baek, Mi H. Kim, Hee J. Jang, Jung S. Park, Ik J. Chung, Boo A. Shin, Bong W. Ahn, Young D. Jung
Pages: 1569-1575
Published online on: 01 December 2008

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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