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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2008 Volume 20 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Glutathione peroxidase 3 is a candidate mechanism of anticancer drug resistance of ovarian clear cell adenocarcinoma

Yasushi Saga, Michitaka Ohwada, Mitsuaki Suzuki, Ryo Konno, Junzo Kigawa, Shuichi Ueno, Hiroyuki Mano
Pages: 1299-1303
Published online on: 01 December 2008

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Article

Clinical responses in patients with advanced colorectal cancer to a dendritic cell based vaccine

Stefan K. Burgdorf, Anders Fischer, Peter S. Myschetzky, Signe B. Munksgaard, Mai-Britt Zocca, Mogens H. Claesson, Jacob Rosenberg
Pages: 1305-1311
Published online on: 01 December 2008

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Article

Clinical significance of ApoE expression in human gastric cancer

Katsuya Sakashita, Fumiaki Tanaka, Xiang Zhang, Koshi Mimori, Yukio Kamohara, Hiroshi Inoue, Tetsuji Sawada, Kosei Hirakawa, Masaki Mori
Pages: 1313-1319
Published online on: 01 December 2008

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Article

Guggulsterone inhibits angiogenesis by blocking STAT3 and VEGF expression in colon cancer cells

Eun Soo Kim, Sung Yi Hong, Hye Kyung Lee, Seung Won Kim, Min Ji An, Tae Il Kim, Kyoung Ryul Lee, Won Ho Kim, Jae Hee Cheon
Pages: 1321-1327
Published online on: 01 December 2008

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Article

N-myc downstream regulated gene 1 (NDRG1)/Cap43 enhances portal vein invasion and intrahepatic metastasis in human hepatocellular carcinoma

Jun Akiba, Sachiko Ogasawara, Akihiko Kawahara, Naoyo Nishida, Sakiko Sanada, Fukuko Moriya, Michihiko Kuwano, Osamu Nakashima, Hirohisa Yano
Pages: 1329-1335
Published online on: 01 December 2008

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Article

ILK overexpression in human hepatocellular carcinoma and liver cirrhosis correlates with activation of Akt

Stavros Peroukides, Vasiliki Bravou, John Varakis, Alexandros Alexopoulos, Haralabos Kalofonos, Helen Papadaki
Pages: 1337-1344
Published online on: 01 December 2008

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Article

Targeting β1 integrin restores sensitivity to docetaxel of esophageal squamous cell carcinoma

Ryota Mori, Hideyuki Ishiguro, Yoshiyuki Kuwabara, Masahiro Kimura, Akira Mitsui, Keisuke Tomoda, Yoichiro Mori, Ryo Ogawa, Takeyasu Katada, Koshiro Harata, Yoshitaka Fujii
Pages: 1345-1351
Published online on: 01 December 2008

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Article

Inhibition of syndecan-1 expression and function in oral cancer cells

Takashi Muramatsu, Masato Saitoh, Yasufumi Ro, Tomoko Uekusa, Eri Iwamura, Kazumasa Ohta, Yohko Kohno, Yoshihiro Abiko, Masaki Shimono
Pages: 1353-1357
Published online on: 01 December 2008

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Article

Blazein of a new steroid isolated from Agaricus blazei Murrill (himematsutake) induces cell death and morphological change indicative of apoptotic chromatin condensation in human lung cancer LU99 and stomach cancer KATO III cells

Hiroko Itoh, Hitoshi Ito, Hiroshige Hibasami
Pages: 1359-1361
Published online on: 01 December 2008

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Article

Anti-tumor effects of telomelysin for head and neck squamous cell carcinoma

Kyoko Fujita, Machiko Kimura, Norio Kondo, Atsuko Sakakibara, Daisuke Sano, Yukari Ishiguro, Mamoru Tsukuda
Pages: 1363-1368
Published online on: 01 December 2008

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Article

Solid neuroendocrine breast carcinomas: Incidence, clinico-pathological features and immunohistochemical profiling

Eugeni López-Bonet, Miguel Alonso-Ruano, Graciela Barraza, Alejandro Vazquez-Martin, Luis Bernadó, Javier A. Menendez
Pages: 1369-1374
Published online on: 01 December 2008

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Article Open Access

Secretion of N-ERC/mesothelin and expression of C-ERC/mesothelin in human pancreatic ductal carcinoma

Koichi Inami, Kazunori Kajino, Masaaki Abe, Yoshiaki Hagiwara, Masahiro Maeda, Masafumi Suyama, Sumio Watanabe, Okio Hino
Pages: 1375-1380
Published online on: 01 December 2008

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Article

Expression of Glut-1 is a prognostic marker for oral squamous cell carcinoma patients

A. W. Eckert, M. H.W. Lautner, H. Taubert, J. Schubert, U. Bilkenroth
Pages: 1381-1385
Published online on: 01 December 2008

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Article

Glycyrrhizin induces apoptosis in prostate cancer cell lines DU-145 and LNCaP

Sivasakthivel Thirugnanam, Lipeng Xu, Kalyanasundaram Ramaswamy, Munirathinam Gnanasekar
Pages: 1387-1392
Published online on: 01 December 2008

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Article

Specific rearrangement of the microtubular network during the cell cycle phases and correlation with micronucleation and death induced by anticancer drugs in NIH/3T3 subcultures

Alessandra Spano, Gianni Monaco, Sergio Barni, Luigi Sciola
Pages: 1393-1402
Published online on: 01 December 2008

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Article

Decreased expression of galectin-3 predicts tumour recurrence in pTa bladder cancer

Mario Wolfgang Kramer, Markus Antonius Kuczyk, Jörg Hennenlotter, Jürgen Serth, David Schilling, Arnulf Stenzl, Axel Stuart Merseburger
Pages: 1403-1408
Published online on: 01 December 2008

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Article

Activation of mTOR in a subgroup of ovarian carcinomas: Correlation with p-eIF-4E and prognosis

Aurelia Noske, Juliane Lena Lindenberg, Silvia Darb-Esfahani, Wilko Weichert, Ann-Christin Buckendahl, Annika Röske, Jalid Sehouli, Manfred Dietel, Carsten Denkert
Pages: 1409-1417
Published online on: 01 December 2008

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Article

Evaluation of cytotoxic effects induced by bcl-2 and bcl-xL antisense-oligodeoxynucleotides in normal urothelium and transitional cell carcinoma

Ute Gabriel, Christian Bolenz, Andreas Becker, Axel Schaaf, Annette Steidler, Lutz Trojan, Christel Weiss, Maurice Stephan Michel
Pages: 1419-1423
Published online on: 01 December 2008

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Article

Stable suppression of HER-2 gene expression using siRNA increases the lysis of human ovarian carcinoma cells mediated by NK-92 cell line

Ying Zhou, Zhixiang Cheng, Huaiping Zhu, Dingqing Feng, Weidong Zhao, Bin Ling, Haiming Wei, Zhigang Tian
Pages: 1425-1431
Published online on: 01 December 2008

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Article

Specific reversal of MDR1/P-gp-dependent multidrug resistance by RNA interference in colon cancer cells

Zhongsheng Xia, Zhaohua Zhu, Liyong Zhang, Crista Royal, Zhongmin Liu, Qikui Chen, Bao-Ling Adam
Pages: 1433-1439
Published online on: 01 December 2008

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Article

Overexpression of insulin-like growth factor binding protein 3 in oral squamous cell carcinoma

Lai-Ping Zhong, Xiao Yang, Lei Zhang, Kui-Jie Wei, Hong-Ya Pan, Xiao-Jian Zhou, Jiang Li, Wan-Tao Chen, Zhi-Yuan Zhang
Pages: 1441-1447
Published online on: 01 December 2008

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Article

Soluble transforming growth factor β type II receptor attenuates TGF-β1 activity in human colorectal cancer LoVo cells

Rui Zhou, Bin Xiong, Haibin Song, Shiquan Liu, Xinbo Wang
Pages: 1449-1456
Published online on: 01 December 2008

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Article

Glioma cells enhance endothelial progenitor cell angiogenesis via VEGFR-2, not VEGFR-1

Junxia Zhang, Peng Zhao, Zhen Fu, Xiaolei Chen, Ning Liu, Ailin Lu, Rui Li, Lei Shi, Peiyu Pu, Chunsheng Kang, Yongping You
Pages: 1457-1463
Published online on: 01 December 2008

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Article

Survival advantages of multicellular spheroids vs. monolayers of HepG2 cells in vitro

Chun-Li Li, Tao Tian, Ke-Jun Nan, Na Zhao, Ya-Huan Guo, Jie Cui, Jin Wang, Wang-Gang Zhang
Pages: 1465-1471
Published online on: 01 December 2008

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Article

TAE226, a dual inhibitor for FAK and IGF-IR, has inhibitory effects on mTOR signaling in esophageal cancer cells

Zhi Gang Wang, Takuya Fukazawa, Toshio Nishikawa, Nobuyuki Watanabe, Kazufumi Sakurama, Takayuki Motoki, Munenori Takaoka, Shinji Hatakeyama, Osamu Omori, Toshiaki Ohara, Shunsuke Tanabe, Yasuhiro Fujiwara, Yasuhiro Shirakawa, Tomoki Yamatsuji, Noriaki Tanaka, Yoshio Naomoto
Pages: 1473-1477
Published online on: 01 December 2008

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Article

Inhibitory effect of green tea extract and (−)-epigallocatechin-3-gallate on mammalian thioredoxin reductase and HeLa cell viability

Yan Wang, Huihui Zhang, Arne Holmgren, Weixi Tian, Liangwei Zhong
Pages: 1479-1487
Published online on: 01 December 2008

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Article

Quantitative detection of TIMP-3 promoter hypermethylation and its prognostic significance in esophageal squamous cell carcinoma

Itasu Ninomiya, Kazuyuki Kawakami, Sachio Fushida, Takashi Fujimura, Hiroshi Funaki, Hiroyuki Takamura, Hirohisa Kitagawa, Hisatoshi Nakagawara, Hidehiro Tajima, Masato Kayahara, Tetsuo Ohta
Pages: 1489-1495
Published online on: 01 December 2008

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Article

Matrix metalloproteinase-1 is a crucial bone metastasis factor in a human breast cancer-derived highly invasive cell line

Noritaka Okuyama, Akihiko Matsumine, Rieko Kosugi, Hiroki Wakabayashi, Atsumasa Uchida
Pages: 1497-1504
Published online on: 01 December 2008

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Article

Fermented Noni Exudate (fNE): A mediator between immune system and anti-tumor activity

Jinhua Li, Sara L. Stickel, Hilary Bouton-Verville, Kelly E. Burgin, Xianzhong Yu, Desmond K.W. Wong, Thomas E. Wagner, Yanzhang Wei
Pages: 1505-1509
Published online on: 01 December 2008

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Article

Immunological stress in kidney cancer patients undergoing either open nephrectomy or nephron-sparing surgery: An immunophenotypic study of lymphocyte subpopulations and circulating dendritic cells

Camillo Porta, Lucia Bonomi, Beatrice Lillaz, Catherine Klersy, Ilaria Imarisio, Chiara Paglino, Bianca Rovati, Marco Danova, Elisa Ferraris, Mario Mensi, Bruno Rovereto
Pages: 1511-1519
Published online on: 01 December 2008

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Article

Comparison between intravenous and oral postoperative adjuvant immunochemotherapy in patients with stage III colorectal cancer

Isao Ito, Masaya Mukai, Hiromi Ninomiya, Kyoko Kishima, Kazutoshi Tsuchiya, Takayuki Tajima, Masato Nakamura, Hiroyasu Makuuchi
Pages: 1521-1526
Published online on: 01 December 2008

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Article

Increased growth factor expression after hepatic and pancreatic resection

Christoph Justinger, Christian Schlüter, Vilma Oliviera-Frick, Berit Kopp, Claudia Rubie, Martin K. Schilling
Pages: 1527-1531
Published online on: 01 December 2008

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Article

Concurrent chemobiotherapy with cisplatin, dacarbazine, decrescendo interleukin-2 and interferon α2b in patients with metastatic melanoma

Jair Bar, Rinat Yerushalmi, Roni Shapira-Frummer, Irena Kutchuk, Aaron Sulkes, Haim Gutman, Raphael Catane, Jacob Schachter
Pages: 1533-1538
Published online on: 01 December 2008

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Article

Circulating 25-hydroxyvitamin D concentration in German cancer patients

Uwe Reinhold, Barbara Schmitz, Christian Kurbacher, Wolfgang Nagel, Matthias Schmidt, Willy J. Malaisse
Pages: 1539-1543
Published online on: 01 December 2008

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Article

Decreased orotate phosphoribosyltransferase activity produces 5-fluorouracil resistance in a human gastric cancer cell line

Yasuhiro Tsutani, Kazuhiro Yoshida, Yuichi Sanada, Yoshiyuki Wada, Kazuo Konishi, Masakazu Fukushima, Morihito Okada
Pages: 1545-1551
Published online on: 01 December 2008

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Article

AMPK mediates curcumin-induced cell death in CaOV3 ovarian cancer cells

Wei Pan, Hui Yang, Cong Cao, Xiuzu Song, Brittany Wallin, Rebecca Kivlin, Shan Lu, Gang Hu, Wen Di, Yinsheng Wan
Pages: 1553-1559
Published online on: 01 December 2008

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Article

Analysis of hypoxia-associated gene expression in prostate cancer: lysyl oxidase and glucose transporter-1 expression correlate with Gleason score

Grant D. Stewart, Kelly Gray, Caroline J. Pennington, Dylan R. Edwards, Antony C.P. Riddick, James A. Ross, Fouad K. Habib
Pages: 1561-1567
Published online on: 01 December 2008

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Article

EGF stimulates uPAR expression and cell invasiveness through ERK, AP-1, and NF-κB signaling in human gastric carcinoma cells

Min K. Baek, Mi H. Kim, Hee J. Jang, Jung S. Park, Ik J. Chung, Boo A. Shin, Bong W. Ahn, Young D. Jung
Pages: 1569-1575
Published online on: 01 December 2008

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Recommend to Library

Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

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