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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2009 Volume 21 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Surfactant protein DNA methylation: A new entrant in the field of lung cancer diagnostics? (Review)

Mudit Vaid, Joanna Floros
Pages: 3-11
Published online on: 01 January 2009

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Article

Knockdown of Dicer in MCF-7 human breast carcinoma cells results in G1 arrest and increased sensitivity to cisplatin

Ye Bu, Chunhua Lu, Chunjing Bian, Jinghua Wang, Jing Li, Bin Zhang, Zhenya Li, Gary Brewer, Robert Chunhua Zhao
Pages: 13-17
Published online on: 01 January 2009

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Article

Cripto-1 overexpression is involved in the tumorigenesis of gastric-type and pancreatobiliary-type intraductal papillary mucinous neoplasms of the pancreas

Sung P. Hong, Eun K. Lee, Jeong Y. Park, Tae J. Jeon, Seungmin Bang, Seungwoo Park, Jae B. Chung, Woo J. Lee, Hoguen Kim, Si Y. Song
Pages: 19-24
Published online on: 01 January 2009

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Article

The pro-angiogenic factors stimulated by human papillomavirus type 16 E6 and E7 protein in C33A and human fibroblasts

Ling Xi, Shixuan Wang, Changyu Wang, Qian Xu, Pengcheng Li, Xun Tian, Peng Wu, Wei Wang, Dongrui Deng, Jianfeng Zhou, Ding Ma
Pages: 25-31
Published online on: 01 January 2009

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Article

Overexpression of orotate phosphoribosyl transferase in hormone-refractory prostate cancer

Tomoaki Tanaka, Hidenori Kawashima, Kentaro Matsumura, Tomoko Yamashita-Hosono, Rikio Yoshimura, Katsuyuki Kuratsukuri, Koji Harimoto, Tatsuya Nakatani
Pages: 33-37
Published online on: 01 January 2009

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Article

Quantitative molecular grading of bladder tumours: A tool for objective assessment of the biological potential of urothelial neoplasias

Daniel Bollmann, Magdolna Bollmann, Agnes Bankfalvi, Hildegard Heller, Reinhard Bollmann, Gabor Pajor, Ralf Hildenbrand
Pages: 39-47
Published online on: 01 January 2009

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Article

Prognostic value of MUC4 for mass-forming intrahepatic cholangiocarcinoma after hepatectomy

Chun-Nan Yeh, See-Tong Pang, Ren-Ching Wu, Tsung-Wen Chen, Yi-Yin Jan, Miin-Fu Chen
Pages: 49-56
Published online on: 01 January 2009

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Article

Serum response factor enhances liver metastasis of colorectal carcinoma via alteration of the E-cadherin/β-catenin complex

Ha Na Choi, Kyung Ryoul Kim, Ji Hyun Lee, Ho Sung Park, Kyu Yun Jang, Myoung Ja Chung, Si Eun Hwang, Hee Chul Yu, Woo Sung Moon
Pages: 57-63
Published online on: 01 January 2009

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Article

Expression of CXCL12 and its receptor CXCR4 in esophageal squamous cell carcinoma

Ken Sasaki, Shoji Natsugoe, Sumiya Ishigami, Masataka Matsumoto, Hiroshi Okumura, Tetsuro Setoyama, Yasuto Uchikado, Yoshiaki Kita, Kiyokazu Tamotsu, Koichi Hanazono, Tetsuhiro Owaki, Takashi Aikou
Pages: 65-71
Published online on: 01 January 2009

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Article

Protein profiling of post-prostatic massage urine specimens by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry to discriminate between prostate cancer and benign lesions

Akiko Okamoto, Hayato Yamamoto, Atsushi Imai, Shingo Hatakeyama, Ikuya Iwabuchi, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Noritaka Kamimura, Kazuyuki Mori, Kanemitsu Yamaya, Chikara Ohyama
Pages: 73-79
Published online on: 01 January 2009

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Article

Association between expression of human papillomavirus 16/18 E6 oncoprotein and survival in patients with stage I non-small cell lung cancer

Nan-Yung Hsu, Ya-Wen Cheng, I-Ping Chan, Heng-Chien Ho, Chih-Yi Chen, Chung-Ping Hsu, Meng-Hung Lin, Ming-Chih Chou
Pages: 81-87
Published online on: 01 January 2009

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Article

A new therapeutic modality involving acridine orange excitation by photon energy used during reduction surgery for rhabdomyosarcomas

Takao Matsubara, Katsuyuki Kusuzaki, Akihiko Matsumine, Hiroaki Murata, Haruhiko Satonaka, Ken Shintani, Tomoki Nakamura, Hajime Hosoi, Tomoko Iehara, Toru Sugimoto, Atsumasa Uchida
Pages: 89-94
Published online on: 01 January 2009

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Article

Immunohistochemical analysis of Reg IV in urogenital organs: Frequent expression of Reg IV in prostate cancer and potential utility as serum tumor marker

Tetsutaro Hayashi, Akio Matsubara, Shinya Ohara, Koji Mita, Yasuhisa Hasegawa, Tsuguru Usui, Koji Arihiro, Shinichi Norimura, Kazuhiro Sentani, Naohide Oue, Wataru Yasui
Pages: 95-100
Published online on: 01 January 2009

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Article

Clinical significance of chicken ovalbumin upstream promoter-transcription factor II expression in human colorectal cancer

Sung-Won Shin, Hyuk-Chan Kwon, Mee-Sook Rho, Hong-Jo Choi, Jong-Young Kwak, Joo-In Park
Pages: 101-106
Published online on: 01 January 2009

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Article Open Access

Gastric-and-intestinal mixed endocrine cell phenotypic expression of carcinoid tumors in the rectum

Yoshikazu Hirata, Tsutomu Mizoshita, Takashi Mizushima, Takaya Shimura, Yoshinori Mori, Eiji Kubota, Tsuneya Wada, Naotaka Ogasawara, Satoshi Tanida, Hiromi Kataoka, Makoto Sasaki, Takeshi Kamiya, Tetsuya Tsukamoto, Masae Tatematsu, Takashi Joh
Pages: 107-112
Published online on: 01 January 2009

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Article

Claudin expression in rectal well-differentiated endocrine neoplasms (carcinoid tumors)

Mitsuaki Ishida, Ryoji Kushima, Hidetoshi Okabe
Pages: 113-117
Published online on: 01 January 2009

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Article

Characterization of a GM7 glioblastoma cell line showing CD133 positivity and both cytoplasmic and nuclear localization of nestin

Tomas Loja, Petr Chlapek, Petr Kuglik, Martina Pesakova, Alexandra Oltova, Pavel Cejpek, Renata Veselska
Pages: 119-127
Published online on: 01 January 2009

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Article

Focal adhesion kinase: Important to prostaglandin E2-mediated adhesion, migration and invasion in hepatocellular carcinoma cells

Xiao-Ming Bai, Wei Zhang, Ning-Bo Liu, Hui Jiang, Ke-Xin Lou, Tao Peng, Juan Ma, Li Zhang, Hai Zhang, Jing Leng
Pages: 129-136
Published online on: 01 January 2009

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Article

Relationship of activated extracellular signal-regulated kinase 1/2 with lung metastasis in salivary adenoid cystic carcinoma

Kai Hu, Ye-Hua Gan, Sheng-Lin Li, Yan Gao, Deng-Cheng Wu, Cun-Yu Wang, Guang-Yan Yu
Pages: 137-143
Published online on: 01 January 2009

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Article

A low molecular weight polysaccharide isolated from Agaricus blazei suppresses tumor growth and angiogenesis in vivo

Y. C. Niu, J. C. Liu, X. M. Zhao, X. X. Wu
Pages: 145-152
Published online on: 01 January 2009

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Article

Decreased expression of the chemokine CCL21 in human colorectal adenocarcinomas

Melad Mumtaz, Dick Wågsäter, Sture Löfgren, Anders Hugander, Niklas Zar, Jan Dimberg
Pages: 153-158
Published online on: 01 January 2009

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Article

Decreased expression of KAI1/CD82 metastasis suppressor gene is associated with loss of heterozygosity in melanoma cell lines

Young Il Kim, Min-Kyung Shin, Jin-Woo Lee, Joo-Ho Chung, Mu-Hyoung Lee
Pages: 159-164
Published online on: 01 January 2009

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Article

Retargeting improves the efficacy of a telomerase-dependent oncolytic adenovirus for head and neck cancer

Raine Toivonen, Elina Suominen, Reidar Grenman, Mikko Savontaus
Pages: 165-171
Published online on: 01 January 2009

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Article Open Access

Impaired ζ chain expression and IFN-γ production in peripheral blood T and NK cells of patients with advanced lung cancer

Lidia Ciszak, Agata Kosmaczewska, Bozena Werynska, Aleksandra Szteblich, Renata Jankowska, Irena Frydecka
Pages: 173-184
Published online on: 01 January 2009

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Article

Isothiocyanates repress estrogen receptor α expression in breast cancer cells

Lianguo Kang, Ling Ding, Zhao-Yi Wang
Pages: 185-192
Published online on: 01 January 2009

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Article

Medium adsorbance fraction of reticulocyte and myeloperoxidase index may individuate a patient subset with a low risk of chemotherapy-related neutropenia

Giulio Giordano, Pier Francesco Ferrucci, Chiara Nicci, Tiziana Grafone, Rosa Tambaro, Stefano Papini, Giuliana Farina, Silvia Piano, Bruno Zappacosta, Sergio Storti
Pages: 193-198
Published online on: 01 January 2009

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Article

Mitochondrial ultrastructure-associated chemotherapy response in ovarian cancer

Motoaki Saitou, Seiji Isonishi, Tomomi Hamada, Takako Kiyokawa, Toshiaki Tachibana, Hiroshi Ishikawa, Makoto Yasuda
Pages: 199-204
Published online on: 01 January 2009

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Article

Inhibition of TGF-β1 suppresses motility and invasiveness of oral squamous cell carcinoma cell lines via modulation of integrins and down-regulation of matrix-metalloproteinases

Sayaka Takayama, Masashi Hatori, Yuji Kurihara, Yuriko Kinugasa, Tatsuo Shirota, Satoru Shintani
Pages: 205-210
Published online on: 01 January 2009

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Article

Overexpression of the fibroblast growth factor receptor-1 gene correlates with liver metastasis in colorectal cancer

Tsutomu Sato, Takashi Oshima, Kazue Yoshihara, Naoto Yamamoto, Roppei Yamada, Yasuhiko Nagano, Shoichi Fujii, Chikara Kunisaki, Manabu Shiozawa, Makoto Akaike, Yasushi Rino, Katsuaki Tanaka, Munetaka Masuda, Toshio Imada
Pages: 211-216
Published online on: 01 January 2009

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Article

Progression of breast tumors is accompanied by a decrease in expression of the Rho guanine exchange factor Tiam1

A. Stebel, C. Brachetti, M. Kunkel, M. Schmidt, G. Fritz
Pages: 217-222
Published online on: 01 January 2009

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Article

Long-term trends of the incidence of hepatocellular carcinoma in the Nagasaki prefecture, Japan

Naota Taura, Hiroshi Yatsuhashi, Kazuhiko Nakao, Tatsuki Ichikawa, Hiromi Ishibashi
Pages: 223-227
Published online on: 01 January 2009

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Article

The expression of CRM1 is associated with prognosis in human osteosarcoma

Yang Yao, Yang Dong, Feng Lin, Hui Zhao, Zan Shen, Ping Chen, Yuan-Jue Sun, Li-Na Tang, Shui-Er Zheng
Pages: 229-235
Published online on: 01 January 2009

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Article

Oxygen-dependent regulation of NDRG1 in human glioblastoma cells in vitro and in vivo

Harun M. Said, Susanne Stein, Carsten Hagemann, Buelent Polat, Adrian Staab, Jelena Anacker, Beate Schoemig, Matthias Theobald, Michael Flentje, Dirk Vordermark
Pages: 237-246
Published online on: 01 January 2009

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Article

DNA cytometry and kinetics of rat urothelial lesions during chemical carcinogenesis

C. Palmeira, P. A. Oliveira, R. Arantes-Rodrigues, A. Colaço, P. L.F. De la Cruz, C. Lopes, L. Santos
Pages: 247-252
Published online on: 01 January 2009

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Article

Tiron, a ROS scavenger, protects human lung cancer Calu-6 cells against antimycin A-induced cell death

Yong Hwan Han, Woo Hyun Park
Pages: 253-261
Published online on: 01 January 2009

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Article

ABCC10/MRP7 is associated with vinorelbine resistance in non-small cell lung cancer

Yuji Bessho, Tetsuya Oguri, Hiroaki Ozasa, Takehiro Uemura, Hideo Sakamoto, Mikinori Miyazaki, Ken Maeno, Shigeki Sato, Ryuzo Ueda
Pages: 263-268
Published online on: 01 January 2009

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

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