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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2017 Volume 38 Issue 6

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Dabrafenib in patients with recurrent, BRAF V600E mutated malignant glioma and leptomeningeal disease

Michael C. Burger, Michael W. Ronellenfitsch, Nadja I. Lorenz, Marlies Wagner, Martin Voss, David Capper, Theophilos Tzaridis, Ulrich Herrlinger, Joachim P. Steinbach, Gabriele Stoffels, Karl-Josef Langen, Christian Brandts, Christian Senft, Patrick N. Harter, Oliver Bähr
Pages: 3291-3296
Published online on: 02 October 2017

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Article Open Access

Formyl peptide receptor 2 expression predicts poor prognosis and promotes invasion and metastasis in epithelial ovarian cancer Retraction in /10.3892/or.2025.8922

Xiaohui Xie, Mengyuan Yang, Yiling Ding, Ling Yu, Jianlin Chen
Pages: 3297-3308
Published online on: 13 October 2017

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Article Open Access

Blockade of α7 nicotinic acetylcholine receptors inhibit nicotine-induced tumor growth and vimentin expression in non-small cell lung cancer through MEK/ERK signaling way

Chun Zhang, Ping Yu, Liang Zhu, Qingnan Zhao, Xiaotong Lu, Shuhong Bo
Pages: 3309-3318
Published online on: 02 October 2017

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Article Open Access

Quercetrin from Toona sinensis leaves induces cell cycle arrest and apoptosis via enhancement of oxidative stress in human colorectal cancer SW620 cells

Yali Zhang, Yucheng Guo, Mimi Wang, Huanhuan Dong, Jingfang Zhang, Liyu Zhang
Pages: 3319-3326
Published online on: 17 October 2017

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Article Open Access

BAF53a is a potential prognostic biomarker and promotes invasion and epithelial-mesenchymal transition of glioma cells

Li Meng, Xiaoyi Wang, Weihua Liao, Jianling Liu, Yiwei Liao, Qiongqiong He
Pages: 3327-3334
Published online on: 10 October 2017

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Article Open Access

Establishment of a human primary pancreatic cancer mouse model to examine and investigate gemcitabine resistance

Ya-Jing Zhang, Chen-Lei Wen, Yu-Xin Qin, Xiao-Mei Tang, Min-Min Shi, Bai-Yong Shen, Yuan Fang
Pages: 3335-3346
Published online on: 12 October 2017

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Article Open Access

Knockdown of lncRNA-XIST enhances the chemosensitivity of NSCLC cells via suppression of autophagy

Wei Sun, Yukun Zu, Xiangning Fu, Yu Deng
Pages: 3347-3354
Published online on: 24 October 2017

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Article Open Access

c-Fos mediates α1, 2-fucosyltransferase 1 and Lewis y expression in response to TGF-β1 in ovarian cancer

Yingying Hao, Liancheng Zhu, Limei Yan, Juanjuan Liu, Dawo Liu, Na Gao, Mingzi Tan, Song Gao, Bei Lin
Pages: 3355-3366
Published online on: 23 October 2017

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Article Open Access

The FOXM1/BUB1B signaling pathway is essential for the tumorigenicity and radioresistance of glioblastoma

Qing Ma, Yanmei Liu, Liang Shang, Jiao Yu, Qiumin Qu
Pages: 3367-3375
Published online on: 12 October 2017

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Article Open Access

Downregulation of miR-874-3p promotes chemotherapeutic resistance in colorectal cancer via inactivation of the Hippo signaling pathway

Kaiqian Que, Yuanhe Tong, Ganbo Que, Li Li, Hongcheng Lin, Shuai Huang, Ruoyu Wang, Langlang Tang
Pages: 3376-3386
Published online on: 17 October 2017

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Article Open Access

Knockdown of HIP1 expression promotes ligand‑induced endocytosis of EGFR in HeLa cells

Dan Li, Fenglin Chen, Jian Ding, Na Lin, Zonghai Li, Xiaozhong Wang
Pages: 3387-3391
Published online on: 12 October 2017

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Article Open Access

Genome-wide analysis of the three-way interplay among gene expression, estrogen receptor expression and chemotherapeutic sensitivity in breast cancer

Dong-Xu He, Xiao-Li Wu, Chun-Xiao Lu, Xiao-Ting Gu, Guang-Yuan Zhang, Xin Ma, De-Quan Liu
Pages: 3392-3402
Published online on: 12 October 2017

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Article Open Access

A seven-gene prognostic signature for rapid determination of head and neck squamous cell carcinoma survival

Sipeng Shen, Jianling Bai, Yongyue Wei, Guanrong Wang, Qingya Li, Ruyang Zhang, Weiwei Duan, Sheng Yang, Mulong Du, Yang Zhao, David C. Christiani, Feng Chen
Pages: 3403-3411
Published online on: 24 October 2017

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Article Open Access

Antiproliferative effects of TSA, PXD‑101 and MS‑275 in A2780 and MCF7 cells: Acetylated histone H4 and acetylated tubulin as markers for HDACi potency and selectivity

Vasilis P. Androutsopoulos, Demetrios A. Spandidos
Pages: 3412-3418
Published online on: 06 October 2017

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Article Open Access

Tumor molecular profiling of NSCLC patients using next generation sequencing

Nikolaos Tsoulos, Eirini Papadopoulou, Vasiliki Metaxa-Mariatou, Georgios Tsaousis, Chrisoula Efstathiadou, Georgia Tounta, Aikaterini Scapeti, Eugenia Bourkoula, Pavlos Zarogoulidis, George Pentheroudakis, Stylianos Kakolyris, Ioannis Boukovinas, Pavlos Papakotoulas, Elias Athanasiadis, Theofanis Floros, Anna Koumarianou, Vasileios Barbounis, Anca Dinischiotu, George Nasioulas
Pages: 3419-3429
Published online on: 23 October 2017

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Article

Hovenia dulcis Thunb. and its active compound ampelopsin inhibit angiogenesis through suppression of VEGFR2 signaling and HIF-1α expression

Jang Mi Han, Haet Nim Lim, Hye Jin Jung
Pages: 3430-3438
Published online on: 11 October 2017

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Article

Synergism between α-mangostin and TRAIL induces apoptosis in squamous cell carcinoma of the oral cavity through the mitochondrial pathway

Masakatsu Fukuda, Hide Sakashita, Hiroyasu Hayashi, Junya Shiono, Genki Miyake, Yusuke Komine, Fuyoko Taira, Hideaki Sakashita
Pages: 3439-3446
Published online on: 12 October 2017

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Article

Suppressive role of miR-592 in breast cancer by repressing TGF-β2

Wenli Hou, Haipeng Zhang, Xiaoxue Bai, Xiaofeng Liu, Yunhe Yu, Lelian Song, Ye Du
Pages: 3447-3454
Published online on: 12 October 2017

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Article

Huaier extract enhances the treatment efficacy of paclitaxel in breast cancer cells via the NF-κB/IκBα pathway

Liu Yang, Zhenchuan Song, Xinle Wang, Wei Yang, Meiqi Wang, Huan Liu
Pages: 3455-3464
Published online on: 12 October 2017

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Article

lncRNA-MIAT regulates cell biological behaviors in gastric cancer through a mechanism involving the miR-29a-3p/HDAC4 axis Retraction in /10.3892/or.2025.8902

Yanfeng Li, Kuan Wang, Yuzhe Wei, Qiang Yao, Qifan Zhang, Hongyan Qu, Guanyu Zhu
Pages: 3465-3472
Published online on: 10 October 2017

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Article

Shikonin induces apoptosis and G0/G1 phase arrest of gallbladder cancer cells via the JNK signaling pathway

Tianyu Zhai, Zhenyu Hei, Qiang Ma, Haibin Liang, Yi Xu, Yichi Zhang, Longyang Jin, Chao Han, Jiandong Wang
Pages: 3473-3480
Published online on: 17 October 2017

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Article Open Access

Long non-coding RNA, steroid receptor RNA activator (SRA), induces tumor proliferation and invasion through the NOTCH pathway in cervical cancer cell lines

Kyung Jin Eoh, Jiheum Paek, Sang Wun Kim, Hee Jung Kim, Hye Yeon Lee, Sang Kil Lee, Young Tae Kim
Pages: 3481-3488
Published online on: 11 October 2017

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Article

Immature colon carcinoma transcript-1 promotes cell growth of hepatocellular carcinoma via facilitating cell cycle progression and apoptosis resistance

Weiping Chang, Zhaoxiang Yu, Ming Tian, Xiaobo Lin
Pages: 3489-3496
Published online on: 19 October 2017

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Article

Expression of fatty acid synthase is regulated by PGC‑1α and contributes to increased cell proliferation

Seong-Hoon Yun, Sung-Won Shin, Joo-In Park
Pages: 3497-3506
Published online on: 18 October 2017

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Article

The recombinant EGFR/CD13 bi-targeted fusion protein induces apoptosis and blocks tube formation

Weijin Sheng, Jianhua Gong, Min Jiang, Yongsu Zhen
Pages: 3507-3514
Published online on: 23 October 2017

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Article

A single nucleotide polymorphism located in microRNA-499a causes loss of function resulting in increased expression of osbpl1a and reduced serum HDL level

Li-Bo Chen, Hai-Kuo Zheng, Lei Zhang, Zhe An, Xin-Peng Wang, Rui-Ting Shan, Wen-Qi Zhang
Pages: 3515-3521
Published online on: 09 October 2017

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Article

miR-149 suppresses human non-small cell lung cancer growth and metastasis by inhibiting the FOXM1/cyclin D1/MMP2 axis

Lijiang Zhao, Lijuan Liu, Zheng Dong, Jie Xiong
Pages: 3522-3530
Published online on: 20 October 2017

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Article

Deubiquitinase USP9X promotes cell migration, invasion and inhibits apoptosis of human pancreatic cancer

Li Liu, Dan Yao, Pengbo Zhang, Weichao Ding, Xiuzhong Zhang, Chong Zhang, Shuai Gong, Yi Zhang, Jike Wang, Ting Sun, Zeqiang Ren
Pages: 3531-3537
Published online on: 20 October 2017

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Article

A panel of markers for identification of malignant and non-malignant cells in culture from effusions

Fabiana Pirani Carneiro, Maria Imaculada Muniz-Junqueira, Fabio Pittella-Silva, Marcos de Vasconcelos Carneiro, Gustavo Henrique Soares Takano, Leonora Maciel de Sousa Vianna, Luciano Barbosa De Andrade, Tercia Maria Mendes Lousa De Castro, Isabela Peres, Tatiana Karla Dos Santos Borges, Vânia Moraes Ferreira, Andrea Barretto Motoyama
Pages: 3538-3544
Published online on: 11 October 2017

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Article

Upregulation of miR-542-3p inhibits the growth and invasion of human colon cancer cells through PI3K/AKT/survivin signaling

Chuang Yang, Ming-Huan Wang, Jun-De Zhou, Qiang Chi
Pages: 3545-3553
Published online on: 23 October 2017

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Article

Inhibition of cell migration and invasion by miR‑29a‑3p in a colorectal cancer cell line through suppression of CDC42BPA mRNA expression

Pei Yuan He, Wai Kien Yip, Boon Lee Chai, Boon Yean Chai, Mohd Faisal Jabar, Noraini Dusa, Norhafizah Mohtarrudin, Heng Fong Seow
Pages: 3554-3566
Published online on: 16 October 2017

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Article

MicroRNA-217 inhibits cell proliferation, invasion and migration by targeting Tpd52l2 in human pancreatic adenocarcinoma

Qiuyang Chen, Peng Wang, Yue Fu, Xinchun Liu, Wenbin Xu, Jishu Wei, Wentao Gao, Kuirong Jiang, Junli Wu, Yi Miao
Pages: 3567-3573
Published online on: 16 October 2017

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Article

Livin promotes the progression and metastasis of breast cancer through the regulation of epithelial‑mesenchymal transition via the p38/GSK3β pathway

Yanchun Han, Li Zhang, Wei Wang, Jia Li, Min Song
Pages: 3574-3582
Published online on: 10 October 2017

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Article

Curcumol inhibits the proliferation of gastric adenocarcinoma MGC-803 cells via downregulation of IDH1

Shilei Zang, Qiling Tang, Fangrui Dong, Huan Liu, Lili Li, Fang Guo, Xuediao Pan, Haorong Lin, Weibin Zeng, Zhaoxu Cai, Qibin Zhong, Ning Zang, Linquan Zang
Pages: 3583-3591
Published online on: 12 October 2017

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Article

Thymoquinone inhibits epithelial-mesenchymal transition in prostate cancer cells by negatively regulating the TGF-β/Smad2/3 signaling pathway Corrigendum in /10.3892/or.2023.8491

Bo Kou, Wei Liu, Wei Zhao, Peng Duan, Yang Yang, Qiuyue Yi, Fengwei Guo, Jianpeng Li, Jinsong Zhou, Qingshan Kou
Pages: 3592-3598
Published online on: 02 October 2017

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Article

Baicalin inhibits the metastasis of highly aggressive breast cancer cells by reversing epithelial-to-mesenchymal transition by targeting β-catenin signaling

Tao Zhou, Aijie Zhang, Ge Kuang, Xia Gong, Rong Jiang, Dan Lin, Jie Li, Hongzhong Li, Xiang Zhang, Jingyuan Wan, Hongyuan Li
Pages: 3599-3607
Published online on: 28 September 2017

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Article

Overexpression of Stathmin 1 correlates with poor prognosis and promotes cell migration and proliferation in oesophageal squamous cell carcinoma

Peng-Zhi Ni, Jian-Zhong He, Zhi-Yong Wu, Xiang Ji, Long-Qi Chen, Xiu-E Xu, Lian-Di Liao, Jian-Yi Wu, En-Min Li, Li-Yan Xu
Pages: 3608-3618
Published online on: 17 October 2017

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Article

Epimedium koreanum Nakai inhibits PMA-induced cancer cell migration and invasion by modulating NF-κB/MMP-9 signaling in monomorphic malignant human glioma cells

Wonil Lee, Jin Han Nam, Hyun-Ji Cho, Ju-Young Lee, Won-Kyung Cho, Υeongyeon Kim, Young-Man We, Jin Yeul Ma, Hyang-Sook Hoe
Pages: 3619-3631
Published online on: 17 October 2017

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Article

Ursodeoxycholic acid suppresses epithelial-mesenchymal transition and cancer stem cell formation by reducing the levels of peroxiredoxin II and reactive oxygen species in pancreatic cancer cells

Yoon Jae Kim, Seok Hoo Jeong, Eun-Kyung Kim, Eui Joo Kim, Jae Hee Cho
Pages: 3632-3638
Published online on: 19 October 2017

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Article

MicroRNA-433 inhibits cervical cancer progression by directly targeting metadherin to regulate the AKT and β-catenin signalling pathways

Changyan Liang, Jie Ding, Yuebo Yang, Liuzhi Deng, Xiaomao Li
Pages: 3639-3649
Published online on: 20 October 2017

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Article

Molecular alterations of the NF2 gene in hepatocellular carcinoma and intrahepatic cholangiocarcinoma

Ning Zhang, Zhang Zhao, Jiang Long, Hai Li, Bei Zhang, Guangyong Chen, Xiaojin Li, Tingxia Lv, Wei Zhang, Xiaojuan Ou, Anjian Xu, Jian Huang
Pages: 3650-3658
Published online on: 24 October 2017

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Article

LARP1 is regulated by the XIST/miR-374a axis and functions as an oncogene in non-small cell lung carcinoma

Zhizheng Xu, Jing Xu, Huoquan Lu, Bin Lin, Shaopeng Cai, Jun Guo, Farong Zang, Rui Chen
Pages: 3659-3667
Published online on: 17 October 2017

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Article

Cisplatin-induced autophagy protects breast cancer cells from apoptosis by regulating yes-associated protein

Yulin Jiang, Feihu Ji, Yifeng Liu, Mengjia He, Zhiqian Zhang, Junhong Yang, Nian Wang, Changli Zhong, Qianni Jin, Xiangsen Ye, Tingmei Chen
Pages: 3668-3676
Published online on: 16 October 2017

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Article

miR-363 inhibits the growth, migration and invasion of hepatocellular carcinoma cells by regulating E2F3 Retraction in /10.3892/or.2021.8181

Junfeng Ye, Wei Zhang, Songyang Liu, Yahui Liu, Kai Liu
Pages: 3677-3684
Published online on: 10 October 2017

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Article

Downregulation of ZNF278 arrests the cell cycle and decreases the proliferation of colorectal cancer cells via inhibition of the ERK/MAPK pathway

Xiao-Qing Tian, Fang-Fang Guo, Dan-Feng Sun, Ying-Chao Wang, Li Yang, Sheng-Liang Chen, Jie Hong, Jing-Yuan Fang
Pages: 3685-3692
Published online on: 12 October 2017

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Article

TGF-β1-induced cell migration in pancreatic carcinoma cells is RAC1 and NOX4-dependent and requires RAC1 and NOX4-dependent activation of p38 MAPK

David Witte, Tobias Bartscht, Roland Kaufmann, Ralph Pries, Utz Settmacher, Hendrik Lehnert, Hendrik Ungefroren
Pages: 3693-3701
Published online on: 12 October 2017

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Article

Hypoxia-induced inhibition of the endocannabinoid system in glioblastoma cells

Naotoshi Sugimoto, Hiroaki Ishibashi, Hiroyuki Nakamura, Akihiro Yachie, Takako Ohno-Shosaku
Pages: 3702-3708
Published online on: 20 October 2017

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Research progress on plant polysaccharides in the prevention and treatment of tumors (Review)

Jikun Wang, Yihan Wang, Xiwu Zhang
Article Number: 152
Published online on: 26 June 2026

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Article Open Access

PIN1 inhibits ferroptosis in gastric cancer cells by regulating the CPEB1‑GPX4 pathway

Aoran Zeng, Tao Wang, Jie Song, Lili Zhu, Ling Chen, Qi Yuan, Ying Jiang, Ping Zhang, Shengzhong Rong, Jing Wang
Article Number: 151
Published online on: 24 June 2026

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Review Open Access

Tanshinone IIA in breast cancer: Molecular mechanisms, structural optimization and translational challenges (Review)

Xiuxia Li, Linlin Feng
Article Number: 150
Published online on: 23 June 2026

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Retraction Open Access

[Retracted] Kevetrin induces apoptosis in TP53 wild‑type and mutant acute myeloid leukemia cells

Roberta Napolitano, Serena De Matteis, Silvia Carloni, Samantha Bruno, Giulia Abbati, Laura Capelli, Martina Ghetti, Maria Teresa Bochicchio, Chiara Liverani, Laura Mercatali, Daniele Calistri, Antonio Cuneo, Krishna Menon, Gerardo Musuraca, Giovanni Martinelli, Giorgia Simonetti
Article Number: 149
Published online on: 22 June 2026

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Article Open Access

PI3Kδ inhibitor YY‑20394 is effective alone or in combination with Bcl‑2 inhibitor ABT199 in acute myeloid leukemia cells

Yinghua Geng, Lili Zhou, Yan Lou, Jiaqi Chen, Qi Liu, Ji Shen, Yanli Yang, Wenjuan Wu
Article Number: 148
Published online on: 17 June 2026

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Article Open Access

Schisandrin B exhibits anti‑proliferative effects by inducing ferroptosis in pancreatic cancer

Fengjin Li, Jiacai Fu, Xiaowei Lin, Yanting Liu, Lu Yang, Yuxin Li, Tieli Peng, Ling Qi
Article Number: 147
Published online on: 16 June 2026

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Review

Research advances on DKK1 in head and neck squamous cell carcinoma: Linking molecular mechanisms to clinical applications (Review)

Xiaoqian Zhu, Liwei Hong, Weihan Chen, Junjuan Tan, Juju Zhou, Lingya Yang, Yonglin Liu, Tiantian Zhai, Kai Chen
Article Number: 146
Published online on: 16 June 2026

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Article Open Access

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
Article Number: 145
Published online on: 10 June 2026

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Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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Journal Cover
September-2026 Volume 56 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Identification of RRM2 as a key regulator of malignant epithelial cells in gastric cancer through single‑cell transcriptomics

Xinzhen Cai, Yun He, Lili Kang, Dongli Zhou, Mengmeng Wang, Tianyu Ma
Article Number: 154
Published online on: 03 July 2026

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Article

Impact of WFDC2 on the biological functions of cervical cancer cells and the regulation of the ERK/NF‑κB signaling pathway

Yanping Zhang, Hongling Zou, Shufeng Deng, Lvling Zou, Mingzhu Xia, Limin Tao
Article Number: 153
Published online on: 01 July 2026

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