Journal Articles

Open Access

Dabrafenib in patients with recurrent, BRAF V600E mutated malignant glioma and leptomeningeal disease

Michael C. Burger, Michael W. Ronellenfitsch, Nadja I. Lorenz, Marlies Wagner, Martin Voss, David Capper, Theophilos Tzaridis, Ulrich Herrlinger, Joachim P. Steinbach, Gabriele Stoffels, Karl-Josef Langen, Christian Brandts, Christian Senft, Patrick N. Harter, Oliver Bähr

Pages: 3291-3296 Published online on: 02 October 2017
Open Access

Formyl peptide receptor 2 expression predicts poor prognosis and promotes invasion and metastasis in epithelial ovarian cancer

Xiaohui Xie, Mengyuan Yang, Yiling Ding, Ling Yu, Jianlin Chen

Pages: 3297-3308 Published online on: 13 October 2017
Open Access

Blockade of α7 nicotinic acetylcholine receptors inhibit nicotine-induced tumor growth and vimentin expression in non-small cell lung cancer through MEK/ERK signaling way

Chun Zhang, Ping Yu, Liang Zhu, Qingnan Zhao, Xiaotong Lu, Shuhong Bo

Pages: 3309-3318 Published online on: 02 October 2017
Open Access

Quercetrin from Toona sinensis leaves induces cell cycle arrest and apoptosis via enhancement of oxidative stress in human colorectal cancer SW620 cells

Yali Zhang, Yucheng Guo, Mimi Wang, Huanhuan Dong, Jingfang Zhang, Liyu Zhang

Pages: 3319-3326 Published online on: 17 October 2017
Open Access

BAF53a is a potential prognostic biomarker and promotes invasion and epithelial-mesenchymal transition of glioma cells

Li Meng, Xiaoyi Wang, Weihua Liao, Jianling Liu, Yiwei Liao, Qiongqiong He

Pages: 3327-3334 Published online on: 10 October 2017
Open Access

Establishment of a human primary pancreatic cancer mouse model to examine and investigate gemcitabine resistance

Ya-Jing Zhang, Chen-Lei Wen, Yu-Xin Qin, Xiao-Mei Tang, Min-Min Shi, Bai-Yong Shen, Yuan Fang

Pages: 3335-3346 Published online on: 12 October 2017
Open Access

Knockdown of lncRNA-XIST enhances the chemosensitivity of NSCLC cells via suppression of autophagy

Wei Sun, Yukun Zu, Xiangning Fu, Yu Deng

Pages: 3347-3354 Published online on: 24 October 2017
Open Access

c-Fos mediates α1, 2-fucosyltransferase 1 and Lewis y expression in response to TGF-β1 in ovarian cancer

Yingying Hao, Liancheng Zhu, Limei Yan, Juanjuan Liu, Dawo Liu, Na Gao, Mingzi Tan, Song Gao, Bei Lin

Pages: 3355-3366 Published online on: 23 October 2017
Open Access

The FOXM1/BUB1B signaling pathway is essential for the tumorigenicity and radioresistance of glioblastoma

Qing Ma, Yanmei Liu, Liang Shang, Jiao Yu, Qiumin Qu

Pages: 3367-3375 Published online on: 12 October 2017
Open Access

Downregulation of miR-874-3p promotes chemotherapeutic resistance in colorectal cancer via inactivation of the Hippo signaling pathway

Kaiqian Que, Yuanhe Tong, Ganbo Que, Li Li, Hongcheng Lin, Shuai Huang, Ruoyu Wang, Langlang Tang

Pages: 3376-3386 Published online on: 17 October 2017
Open Access

Knockdown of HIP1 expression promotes ligand‑induced endocytosis of EGFR in HeLa cells

Dan Li, Fenglin Chen, Jian Ding, Na Lin, Zonghai Li, Xiaozhong Wang

Pages: 3387-3391 Published online on: 12 October 2017
Open Access

Genome-wide analysis of the three-way interplay among gene expression, estrogen receptor expression and chemotherapeutic sensitivity in breast cancer

Dong-Xu He, Xiao-Li Wu, Chun-Xiao Lu, Xiao-Ting Gu, Guang-Yuan Zhang, Xin Ma, De-Quan Liu

Pages: 3392-3402 Published online on: 12 October 2017
Open Access

A seven-gene prognostic signature for rapid determination of head and neck squamous cell carcinoma survival

Sipeng Shen, Jianling Bai, Yongyue Wei, Guanrong Wang, Qingya Li, Ruyang Zhang, Weiwei Duan, Sheng Yang, Mulong Du, Yang Zhao, David C. Christiani, Feng Chen

Pages: 3403-3411 Published online on: 24 October 2017
Open Access

Tumor molecular profiling of NSCLC patients using next generation sequencing

Nikolaos Tsoulos, Eirini Papadopoulou, Vasiliki Metaxa-Mariatou, Georgios Tsaousis, Chrisoula Efstathiadou, Georgia Tounta, Aikaterini Scapeti, Eugenia Bourkoula, Pavlos Zarogoulidis, George Pentheroudakis, Stylianos Kakolyris, Ioannis Boukovinas, Pavlos Papakotoulas, Elias Athanasiadis, Theofanis Floros, Anna Koumarianou, Vasileios Barbounis, Anca Dinischiotu, George Nasioulas

Pages: 3419-3429 Published online on: 23 October 2017

Synergism between α-mangostin and TRAIL induces apoptosis in squamous cell carcinoma of the oral cavity through the mitochondrial pathway

Masakatsu Fukuda, Hide Sakashita, Hiroyasu Hayashi, Junya Shiono, Genki Miyake, Yusuke Komine, Fuyoko Taira, Hideaki Sakashita

Pages: 3439-3446 Published online on: 12 October 2017

Suppressive role of miR-592 in breast cancer by repressing TGF-β2

Wenli Hou, Haipeng Zhang, Xiaoxue Bai, Xiaofeng Liu, Yunhe Yu, Lelian Song, Ye Du

Pages: 3447-3454 Published online on: 12 October 2017

Huaier extract enhances the treatment efficacy of paclitaxel in breast cancer cells via the NF-κB/IκBα pathway

Liu Yang, Zhenchuan Song, Xinle Wang, Wei Yang, Meiqi Wang, Huan Liu

Pages: 3455-3464 Published online on: 12 October 2017

lncRNA-MIAT regulates cell biological behaviors in gastric cancer through a mechanism involving the miR-29a-3p/HDAC4 axis

Yanfeng Li, Kuan Wang, Yuzhe Wei, Qiang Yao, Qifan Zhang, Hongyan Qu, Guanyu Zhu

Pages: 3465-3472 Published online on: 10 October 2017

Shikonin induces apoptosis and G0/G1 phase arrest of gallbladder cancer cells via the JNK signaling pathway

Tianyu Zhai, Zhenyu Hei, Qiang Ma, Haibin Liang, Yi Xu, Yichi Zhang, Longyang Jin, Chao Han, Jiandong Wang

Pages: 3473-3480 Published online on: 17 October 2017
Open Access

Long non-coding RNA, steroid receptor RNA activator (SRA), induces tumor proliferation and invasion through the NOTCH pathway in cervical cancer cell lines

Kyung Jin Eoh, Jiheum Paek, Sang Wun Kim, Hee Jung Kim, Hye Yeon Lee, Sang Kil Lee, Young Tae Kim

Pages: 3481-3488 Published online on: 11 October 2017

Immature colon carcinoma transcript-1 promotes cell growth of hepatocellular carcinoma via facilitating cell cycle progression and apoptosis resistance

Weiping Chang, Zhaoxiang Yu, Ming Tian, Xiaobo Lin

Pages: 3489-3496 Published online on: 19 October 2017

Expression of fatty acid synthase is regulated by PGC‑1α and contributes to increased cell proliferation

Seong-Hoon Yun, Sung-Won Shin, Joo-In Park

Pages: 3497-3506 Published online on: 18 October 2017

The recombinant EGFR/CD13 bi-targeted fusion protein induces apoptosis and blocks tube formation

Weijin Sheng, Jianhua Gong, Min Jiang, Yongsu Zhen

Pages: 3507-3514 Published online on: 23 October 2017

A single nucleotide polymorphism located in microRNA-499a causes loss of function resulting in increased expression of osbpl1a and reduced serum HDL level

Li-Bo Chen, Hai-Kuo Zheng, Lei Zhang, Zhe An, Xin-Peng Wang, Rui-Ting Shan, Wen-Qi Zhang

Pages: 3515-3521 Published online on: 09 October 2017

miR-149 suppresses human non-small cell lung cancer growth and metastasis by inhibiting the FOXM1/cyclin D1/MMP2 axis

Lijiang Zhao, Lijuan Liu, Zheng Dong, Jie Xiong

Pages: 3522-3530 Published online on: 20 October 2017

Deubiquitinase USP9X promotes cell migration, invasion and inhibits apoptosis of human pancreatic cancer

Li Liu, Dan Yao, Pengbo Zhang, Weichao Ding, Xiuzhong Zhang, Chong Zhang, Shuai Gong, Yi Zhang, Jike Wang, Ting Sun, Zeqiang Ren

Pages: 3531-3537 Published online on: 20 October 2017

A panel of markers for identification of malignant and non-malignant cells in culture from effusions

Fabiana Pirani Carneiro, Maria Imaculada Muniz-Junqueira, Fabio Pittella-Silva, Marcos de Vasconcelos Carneiro, Gustavo Henrique Soares Takano, Leonora Maciel de Sousa Vianna, Luciano Barbosa De Andrade, Tercia Maria Mendes Lousa De Castro, Isabela Peres, Tatiana Karla Dos Santos Borges, Vânia Moraes Ferreira, Andrea Barretto Motoyama

Pages: 3538-3544 Published online on: 11 October 2017

Upregulation of miR-542-3p inhibits the growth and invasion of human colon cancer cells through PI3K/AKT/survivin signaling

Chuang Yang, Ming-Huan Wang, Jun-De Zhou, Qiang Chi

Pages: 3545-3553 Published online on: 23 October 2017

Inhibition of cell migration and invasion by miR‑29a‑3p in a colorectal cancer cell line through suppression of CDC42BPA mRNA expression

Pei Yuan He, Wai Kien Yip, Boon Lee Chai, Boon Yean Chai, Mohd Faisal Jabar, Noraini Dusa, Norhafizah Mohtarrudin, Heng Fong Seow

Pages: 3554-3566 Published online on: 16 October 2017

MicroRNA-217 inhibits cell proliferation, invasion and migration by targeting Tpd52l2 in human pancreatic adenocarcinoma

Qiuyang Chen, Peng Wang, Yue Fu, Xinchun Liu, Wenbin Xu, Jishu Wei, Wentao Gao, Kuirong Jiang, Junli Wu, Yi Miao

Pages: 3567-3573 Published online on: 16 October 2017

Livin promotes the progression and metastasis of breast cancer through the regulation of epithelial‑mesenchymal transition via the p38/GSK3β pathway

Yanchun Han, Li Zhang, Wei Wang, Jia Li, Min Song

Pages: 3574-3582 Published online on: 10 October 2017

Curcumol inhibits the proliferation of gastric adenocarcinoma MGC-803 cells via downregulation of IDH1

Shilei Zang, Qiling Tang, Fangrui Dong, Huan Liu, Lili Li, Fang Guo, Xuediao Pan, Haorong Lin, Weibin Zeng, Zhaoxu Cai, Qibin Zhong, Ning Zang, Linquan Zang

Pages: 3583-3591 Published online on: 12 October 2017

Thymoquinone inhibits epithelial-mesenchymal transition in prostate cancer cells by negatively regulating the TGF-β/Smad2/3 signaling pathway

Bo Kou, Wei Liu, Wei Zhao, Peng Duan, Yang Yang, Qiuyue Yi, Fengwei Guo, Jianpeng Li, Jinsong Zhou, Qingshan Kou

Pages: 3592-3598 Published online on: 02 October 2017

Baicalin inhibits the metastasis of highly aggressive breast cancer cells by reversing epithelial-to-mesenchymal transition by targeting β-catenin signaling

Tao Zhou, Aijie Zhang, Ge Kuang, Xia Gong, Rong Jiang, Dan Lin, Jie Li, Hongzhong Li, Xiang Zhang, Jingyuan Wan, Hongyuan Li

Pages: 3599-3607 Published online on: 28 September 2017

Overexpression of Stathmin 1 correlates with poor prognosis and promotes cell migration and proliferation in oesophageal squamous cell carcinoma

Peng-Zhi Ni, Jian-Zhong He, Zhi-Yong Wu, Xiang Ji, Long-Qi Chen, Xiu-E Xu, Lian-Di Liao, Jian-Yi Wu, En-Min Li, Li-Yan Xu

Pages: 3608-3618 Published online on: 17 October 2017

Epimedium koreanum Nakai inhibits PMA-induced cancer cell migration and invasion by modulating NF-κB/MMP-9 signaling in monomorphic malignant human glioma cells

Wonil Lee, Jin Han Nam, Hyun-Ji Cho, Ju-Young Lee, Won-Kyung Cho, Υeongyeon Kim, Young-Man We, Jin Yeul Ma, Hyang-Sook Hoe

Pages: 3619-3631 Published online on: 17 October 2017

MicroRNA-433 inhibits cervical cancer progression by directly targeting metadherin to regulate the AKT and β-catenin signalling pathways

Changyan Liang, Jie Ding, Yuebo Yang, Liuzhi Deng, Xiaomao Li

Pages: 3639-3649 Published online on: 20 October 2017

Molecular alterations of the NF2 gene in hepatocellular carcinoma and intrahepatic cholangiocarcinoma

Ning Zhang, Zhang Zhao, Jiang Long, Hai Li, Bei Zhang, Guangyong Chen, Xiaojin Li, Tingxia Lv, Wei Zhang, Xiaojuan Ou, Anjian Xu, Jian Huang

Pages: 3650-3658 Published online on: 24 October 2017

LARP1 is regulated by the XIST/miR-374a axis and functions as an oncogene in non-small cell lung carcinoma

Zhizheng Xu, Jing Xu, Huoquan Lu, Bin Lin, Shaopeng Cai, Jun Guo, Farong Zang, Rui Chen

Pages: 3659-3667 Published online on: 17 October 2017

Cisplatin-induced autophagy protects breast cancer cells from apoptosis by regulating yes-associated protein

Yulin Jiang, Feihu Ji, Yifeng Liu, Mengjia He, Zhiqian Zhang, Junhong Yang, Nian Wang, Changli Zhong, Qianni Jin, Xiangsen Ye, Tingmei Chen

Pages: 3668-3676 Published online on: 16 October 2017

miR-363 inhibits the growth, migration and invasion of hepatocellular carcinoma cells by regulating E2F3

Junfeng Ye, Wei Zhang, Songyang Liu, Yahui Liu, Kai Liu

Pages: 3677-3684 Published online on: 10 October 2017

Downregulation of ZNF278 arrests the cell cycle and decreases the proliferation of colorectal cancer cells via inhibition of the ERK/MAPK pathway

Xiao-Qing Tian, Fang-Fang Guo, Dan-Feng Sun, Ying-Chao Wang, Li Yang, Sheng-Liang Chen, Jie Hong, Jing-Yuan Fang

Pages: 3685-3692 Published online on: 12 October 2017

TGF-β1-induced cell migration in pancreatic carcinoma cells is RAC1 and NOX4-dependent and requires RAC1 and NOX4-dependent activation of p38 MAPK

David Witte, Tobias Bartscht, Roland Kaufmann, Ralph Pries, Utz Settmacher, Hendrik Lehnert, Hendrik Ungefroren

Pages: 3693-3701 Published online on: 12 October 2017

Hypoxia-induced inhibition of the endocannabinoid system in glioblastoma cells

Naotoshi Sugimoto, Hiroaki Ishibashi, Hiroyuki Nakamura, Akihiro Yachie, Takako Ohno-Shosaku

Pages: 3702-3708 Published online on: 20 October 2017
Journal Cover

December-2017
Volume 38 Issue 6

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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