Journal Articles

The ‘SPARC’ of life: Analysis of the role of osteonectin/SPARC in pancreatic cancer (Review)

Monica K. Rossi, Manu Gnanamony, Christopher S. Gondi

Pages: 1765-1771 Published online on: 04 March 2016
Open Access

The antitumor effects of geraniol: Modulation of cancer hallmark pathways (Review)

Minsoo Cho, Insuk So, Jung Nyeo Chun, Ju-Hong Jeon

Pages: 1772-1782 Published online on: 09 March 2016

Insights into the distinct roles of MMP-11 in tumor biology and future therapeutics (Review)

Xu Zhang, Shuai Huang, Junchao Guo, Li Zhou, Lei You, Taiping Zhang, Yupei Zhao

Pages: 1783-1793 Published online on: 18 February 2016
Open Access

Hepatocellular carcinoma cell sensitivity to Vγ9Vδ2 T lymphocyte-mediated killing is increased by zoledronate

Shiori Sugai, Toshiaki Yoshikawa, Tatsuaki Iwama, Nobuhiro Tsuchiya, Norihiro Ueda, Norihiro Fujinami, Manami Shimomura, Rong Zhang, Shin Kaneko, Yasushi Uemura, Tetsuya Nakatsura

Pages: 1794-1804 Published online on: 19 February 2016
Open Access

The pro-social neurohormone oxytocin reverses the actions of the stress hormone cortisol in human ovarian carcinoma cells in vitro

Amanda Mankarious, Foram Dave, George Pados, Dimitris Tsolakidis, Yori Gidron, Yefei Pang, Peter Thomas, Marcia Hall, Emmanouil Karteris

Pages: 1805-1814 Published online on: 01 March 2016
Open Access

Human rhabdomyosarcoma cells express functional pituitary and gonadal sex hormone receptors: Therapeutic implications

Agata Poniewierska-Baran, Gabriela Schneider, Wenyue Sun, Ahmed Abdelbaset-Ismail, Frederic G. Barr, Mariusz Z. Ratajczak

Pages: 1815-1824 Published online on: 11 March 2016
Open Access

Drug resistance originating from a TGF-β/FGF-2-driven epithelial-to-mesenchymal transition and its reversion in human lung adenocarcinoma cell lines harboring an EGFR mutation

Ryota Kurimoto, Shunichiro Iwasawa, Takahiro Ebata, Tsukasa Ishiwata, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Shuhei Koide, Atsushi Iwama, Yuichi Takiguchi

Pages: 1825-1836 Published online on: 04 March 2016
Open Access

Regulation of the collagen cross-linking enzymes LOXL2 and PLOD2 by tumor-suppressive microRNA-26a/b in renal cell carcinoma

Akira Kurozumi, Mayuko Kato, Yusuke Goto, Ryosuke Matsushita, Rika Nishikawa, Atsushi Okato, Ichiro Fukumoto, Tomohiko Ichikawa, Naohiko Seki

Pages: 1837-1846 Published online on: 15 March 2016

Survivin selective inhibitor YM155 promotes cisplatin‑induced apoptosis in embryonal rhabdomyosarcoma

Takehisa Ueno, Shuichiro Uehara, Kengo Nakahata, Hiroomi Okuyama

Pages: 1847-1854 Published online on: 10 March 2016
Open Access

miR-223 reverses the resistance of EGFR-TKIs through IGF1R/PI3K/Akt signaling pathway

Jing Han, Fengyi Zhao, Jing Zhang, Haizhen Zhu, Hu Ma, Xuetao Li, Lina Peng, Jianguo Sun, Zhengtang Chen

Pages: 1855-1867 Published online on: 19 February 2016
Open Access

Corilagin suppresses cholangiocarcinoma progression through Notch signaling pathway in vitro and in vivo

Yue Gu, Linfeng Xiao, Yanlin Ming, Zhizhong Zheng, Wengang Li

Pages: 1868-1876 Published online on: 02 March 2016
Open Access

miR-148a downregulates the expression of transforming growth factor-β2 and SMAD2 in gastric cancer

Wei Zhang, Yan Li

Pages: 1877-1885 Published online on: 10 March 2016
Open Access

Transcriptional profiling of breast cancer cells in response to mevinolin: Evidence of cell cycle arrest, DNA degradation and apoptosis

Ali M. Mahmoud, Mourad A.M. Aboul‑Soud, Junkyu Han, Yazeed A. Al‑Sheikh, Ahmed M. Al‑Abd, Hany A. El‑Shemy

Pages: 1886-1894 Published online on: 04 March 2016

Ephedrae herba stimulates hepatocyte growth factor-induced MET endocytosis and downregulation via early/late endocytic pathways in gefitinib-resistant human lung cancer cells

Yukio Nishimura, Sumiko Hyuga, Soichi Takiguchi, Masashi Hyuga, Kazuyuki Itoh, Toshihiko Hanawa

Pages: 1895-1906 Published online on: 07 March 2016

Targeting the MAP kinase pathway in astrocytoma cells using a recombinant anthrax lethal toxin as a way to inhibit cell motility and invasion

Saleh Al-Dimassi, Gilbert Salloum, Bechara Saykali, Oula Khoury, Shihui Liu, Stephen H. Leppla, Ralph Abi-Habib, Mirvat El-Sibai

Pages: 1913-1920 Published online on: 09 March 2016

Proteomic identification of potential cancer markers in human urine using subtractive analysis

Holger Husi, Richard J.E. Skipworth, Andrew Cronshaw, Kenneth C.H. Fearon, James A. Ross

Pages: 1921-1932 Published online on: 07 March 2016

PEG10 promotes human breast cancer cell proliferation, migration and invasion

Xinran Li, Ruijing Xiao, Kingsley Tembo, Ling Hao, Meng Xiong, Shan Pan, Xiangyong Yang, Wen Yuan, Jie Xiong, Qiuping Zhang

Pages: 1933-1942 Published online on: 23 February 2016

p75 neurotrophin receptor expression is a characteristic of the mitotically quiescent cancer stem cell population present in esophageal squamous cell carcinoma

Tetsuji Yamaguchi, Tomoyuki Okumura, Katsuhisa Hirano, Toru Watanabe, Takuya Nagata, Yutaka Shimada, Kazuhiro Tsukada

Pages: 1943-1954 Published online on: 10 March 2016

Prolonged survival in pancreatic cancer patients with increased regucalcin gene expression: Overexpression of regucalcin suppresses the proliferation in human pancreatic cancer MIA PaCa-2 cells in vitro

Masayoshi Yamaguchi, Satoru Osuka, M. Neale Weitzmann, Bassel F. El-Rayes, Mamoru Shoji, Tomiyasu Murata

Pages: 1955-1964 Published online on: 25 February 2016

Integrated analysis of long non-coding RNA competing interactions reveals the potential role in progression of human gastric cancer

Cheng-Yun Li, Ge-Yu Liang, Wen-Zhuo Yao, Jing Sui, Xian Shen, Yan-Qiu Zhang, Hui Peng, Wei-Wei Hong, Yan-Cheng Ye, Zhi-Yi Zhang, Wen-Hua Zhang, Li-Hong Yin, Yue-Pu Pu

Pages: 1965-1976 Published online on: 24 February 2016

Epigenetic silencing of miR-181b contributes to tumorigenicity in colorectal cancer by targeting RASSF1A

Lun-De Zhao, Wei-Wei Zheng, Gao-Xiang Wang, Xiao-Chun Kang, Lei Qin, Juan-Juan Ji, Sha Hao

Pages: 1977-1984 Published online on: 03 March 2016

Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu

Pages: 1985-1996 Published online on: 19 February 2016

miR-135b, upregulated in breast cancer, promotes cell growth and disrupts the cell cycle by regulating LATS2

Kaiyao Hua, Jiali Jin, Junyong Zhao, Jialu Song, Hongming Song, Dengfeng Li, Niraj Maskey, Bingkun Zhao, Chenyang Wu, Hui Xu, Lin Fang

Pages: 1997-2006 Published online on: 22 February 2016

Kaempferol induces ATM/p53-mediated death receptor and mitochondrial apoptosis in human umbilical vein endothelial cells

Chiu-Fang Lee, Jai‑Sing Yang, Fuu-Jen Tsai, Ni-Na Chiang, Chi‑Cheng Lu, Yu-Syuan Huang, Chun Chen, Fu-An Chen

Pages: 2007-2014 Published online on: 04 March 2016

The membrane complement regulatory protein CD59 promotes tumor growth and predicts poor prognosis in breast cancer

Qianwen Ouyang, Long Zhang, Yizhou Jiang, Xiaojian Ni, Sheng Chen, Fugui Ye, Yiqun Du, Liang Huang, Peipei Ding, Na Wang, Chaoqun Yang, Tianbao Huang, Yujing Sun, Shan Li, Yun Xia, Weiguo Hu, Rongcheng Luo, Zhiming Shao

Pages: 2015-2024 Published online on: 24 February 2016

Comparative study of antitumor effects of bromelain and papain in human cholangiocarcinoma cell lines

Alena Müller, Samarpita Barat, Xi Chen, Khac Cuong Bui, Przemyslaw Bozko, Nisar P. Malek, Ruben R. Plentz

Pages: 2025-2034 Published online on: 01 March 2016

Tetrandrine reverses epithelial-mesenchymal transition in bladder cancer by downregulating Gli-1

Yongjian Zhang, Wei Liu, Wenbo He, Yuanyuan Zhang, Xiuling Deng, Yanmin Ma, Jin Zeng, Bo Kou

Pages: 2035-2042 Published online on: 03 March 2016

FAK tyrosine 407 organized with integrin αVβ5 in Hs578Ts(i)8 advanced triple-negative breast cancer cells

Iliet Payan, Susan McDonnell, Haydee M. Torres, Wim F.A. Steelant, Séverine Van Slambrouck

Pages: 2043-2054 Published online on: 07 March 2016

Expression, clinical significance and mechanism of Slit2 in papillary thyroid cancer

Rong-Liang Shi, Ning Qu, Tian Liao, Yu-Long Wang, Yu Wang, Guo-Hua Sun, Qing-Hai Ji

Pages: 2055-2062 Published online on: 02 March 2016

Timosaponin A-III reverses multi-drug resistance in human chronic myelogenous leukemia K562/ADM cells via downregulation of MDR1 and MRP1 expression by inhibiting PI3K/Akt signaling pathway

Jie-Ru Chen, Xiu-Hong Jia, Hong Wang, Ying-Jie Yi, Jian-Yong Wang, You-Jie Li

Pages: 2063-2070 Published online on: 07 March 2016
Open Access

MicroRNA analysis of breast ductal fluid in breast cancer patients

Luisa Matos Do Canto, Catalin Marian, Shawna Willey, Mary Sidawy, Patricia A. Da Cunha, Janice D. Rone, Xin Li, Yuriy Gusev, Bassem R. Haddad

Pages: 2071-2078 Published online on: 10 March 2016

Tetramethylpyrazine inhibits tumor growth of lung cancer through disrupting angiogenesis via BMP/Smad/Id-1 signaling

Youchao Jia, Zhigang Wang, Aimin Zang, Shunchang Jiao, Sumei Chen, Yan Fu

Pages: 2079-2086 Published online on: 15 March 2016

Cisplatin-induced CCL5 secretion from CAFs promotes cisplatin-resistance in ovarian cancer via regulation of the STAT3 and PI3K/Akt signaling pathways

Bo Zhou, Chaoyang Sun, Na Li, Wanying Shan, Hao Lu, Lili Guo, Ensong Guo, Meng Xia, Danhui Weng, Li Meng, Junbo Hu, Ding Ma, Gang Chen

Pages: 2087-2097 Published online on: 15 March 2016

Sinomenine prevents metastasis of human osteosarcoma cells via S phase arrest and suppression of tumor-related neovascularization and osteolysis through the CXCR4-STAT3 pathway

Tao Xie, Hai-Yong Ren, Hai-Qing Lin, Jin-Ping Mao, Ting Zhu, Sheng-Dong Wang, Zhao-Ming Ye

Pages: 2098-2112 Published online on: 04 March 2016

MUC5B silencing reduces chemo-resistance of MCF-7 breast tumor cells and impairs maturation of dendritic cells

Enrique P. García, Inés Tiscornia, Gabriela Libisch, Felipe Trajtenberg, Mariela Bollati-Fogolín, Ernesto Rodríguez, Verónica Noya, Carolina Chiale, Natalie Brossard, Carlos Robello, Federico Santiñaque, Gustavo Folle, Eduardo Osinaga, Teresa Freire

Pages: 2113-2123 Published online on: 10 March 2016

Selection of optimal chelator improves the contrast of GRPR imaging using bombesin analogue RM26

Bogdan Mitran, Zohreh Varasteh, Ram Kumar Selvaraju, Gunnar Lindeberg, Jens Sörensen, Mats Larhed, Vladimir Tolmachev, Ulrika Rosenström, Anna Orlova

Pages: 2124-2134 Published online on: 09 March 2016

MicroRNA-9 suppresses cell migration and invasion through downregulation of TM4SF1 in colorectal cancer

Young Ran Park, Soo Teik Lee, Se Lim Kim, Yu Chuan Liu, Min Ro Lee, Ja Hyun Shin, Seung Young Seo, Seong Hun Kim, In Hee Kim, Seung Ok Lee, Sang Wook Kim

Pages: 2135-2143 Published online on: 09 March 2016
Open Access

Regulation of COX-2 expression and epithelial-to-mesenchymal transition by hypoxia-inducible factor-1α is associated with poor prognosis in hepatocellular carcinoma patients post TACE surgery

Mingsheng Huang, Long Wang, Junwei Chen, Mingjun Bai, Churen Zhou, Sujuan Liu, Qu Lin

Pages: 2144-2154 Published online on: 04 March 2016

Antiproliferative and apoptosis induction of α-mangostin in T47D breast cancer cells

Somchai Kritsanawong, Sukanda Innajak, Masaya Imoto, Ramida Watanapokasin

Pages: 2155-2165 Published online on: 18 February 2016

Atrazine promotes RM1 prostate cancer cell proliferation by activating STAT3 signaling

Kebang Hu, Yong Tian, Yanwei Du, Liandi Huang, Junyu Chen, Na Li, Wei Liu, Zuowen Liang, Lijing Zhao

Pages: 2166-2174 Published online on: 10 March 2016

A novel curcuminoid exhibits enhanced antitumor activity in nasopharyngeal carcinoma

Yunbao Pan, Guohong Liu, Jian Xiao, Bojin Su, Fuling Zhou, Yongchang Wei

Pages: 2175-2183 Published online on: 07 March 2016

CXCR1 promotes malignant behavior of gastric cancer cells in vitro and in vivo in AKT and ERK1/2 phosphorylation

Junpu Wang, Wanming Hu, Xiaoying Wu, Kuansong Wang, Jun Yu, Baihua Luo, Gengqiu Luo, Weiyuan Wang, Huiling Wang, Jinghe Li, Jifang Wen

Pages: 2184-2196 Published online on: 09 March 2016

The levels of HDAC1 and thioredoxin1 are related to the death of mesothelioma cells by suberoylanilide hydroxamic acid

Bo Ra You, Woo Hyun Park

Pages: 2197-2204 Published online on: 19 February 2016

Tanshinone IIA induces TRAIL sensitization of human lung cancer cells through selective ER stress induction

Eun-Ok Kim, Shi Eun Kang, Chang Rak Im, Jun-Hee Lee, Kwang Seok Ahn, Woong Mo Yang, Jae-Young Um, Seok-Geun Lee, Miyong Yun

Pages: 2205-2212 Published online on: 15 March 2016
Journal Cover

Cover Legend PDF

May 2016
Volume 48 Issue 5

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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