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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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February-2017 Volume 15 Issue 2

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Non‑infective occupational risk factors for hepatocellular carcinoma: A review (Review)

Caterina Ledda, Carla Loreto, Christian Zammit, Andrea Marconi, Lucrezia Fago, Serena Matera, Valentina Costanzo, Giovanni Fuccio Sanzà, Stefano Palmucci, Margherita Ferrante, Chiara Costa, Concettina Fenga, Antonio  Biondi, Cristoforo Pomara, Venerando Rapisarda
Pages: 511-533
Published online on: 14 December 2016

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Article Open Access

Expression of miR‑26a exhibits a negative correlation with HMGA1 and regulates cancer progression by targeting HMGA1 in lung adenocarcinoma cells

Noboru Sekimoto, Ayako Suzuki, Yutaka Suzuki, Sumio Sugano
Pages: 534-542
Published online on: 15 December 2016

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Article Open Access

Advanced oxidation protein products induce apoptosis, and upregulate sclerostin and RANKL expression, in osteocytic MLO-Y4 cells via JNK/p38 MAPK activation

Chaoqun Yu, Dong Huang, Kunyuan Wang, Bochuan Lin, Yuanhang Liu, Songbo Liu, Weichi Wu, Huiru Zhang
Pages: 543-550
Published online on: 14 December 2016

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Article Open Access

Reduced miR‑26a and miR‑26b expression contributes to the pathogenesis of osteoarthritis via the promotion of p65 translocation

Xuefeng Yin, Jiang‑Quan Wang, Shu‑Yi Yan
Pages: 551-558
Published online on: 14 December 2016

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Article Open Access

Involvement of interleukin‑23 induced by Porphyromonas endodontalis lipopolysaccharide in osteoclastogenesis

Nan Ma, Di Yang, Hirohiko Okamura, Jumpei Teramachi, Tomokazu Hasegawa, Lihong Qiu, Tatsuji Haneji
Pages: 559-566
Published online on: 14 December 2016

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Article Open Access

Resveratrol inhibits adventitial fibroblast proliferation and induces cell apoptosis through the SIRT1 pathway

Lin Ling, Shaohua Gu, Yan Cheng
Pages: 567-572
Published online on: 30 December 2016

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Article Open Access

Changes in TL1A levels and associated cytokines during pathogenesis of diabetic retinopathy

Zhu‑Hong Zhang, Qing‑Zhong Chen, Feng Jiang, Todd A. Townsend, Chun‑Jie Mao, Cai‑Yun You, Wen‑Hui Yang, Zhi‑Yong Sun, Jin‑Guo Yu, Hua Yan
Pages: 573-580
Published online on: 14 December 2016

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Article Open Access

Genetic heterogeneity in patients with Bartter syndrome type 1

Mingran Sun, Jing Ning, Weihong Xu, Han Zhang, Kaishu Zhao, Wenfu Li, Guiying Li, Shibo Li
Pages: 581-590
Published online on: 21 December 2016

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Article Open Access

Differential expression of microRNA in the lungs of rats with pulmonary arterial hypertension

Tingting Xiao, Lijian Xie, Min Huang, Jie Shen
Pages: 591-596
Published online on: 14 December 2016

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Article Open Access

Role of miR-223/paired box 6 signaling in temozolomide chemoresistance in glioblastoma multiforme cells

Quan Cheng, Xiaoqiang Ma, Hui Cao, Zigui Chen, Xin Wan, Rui Chen, Renjun Peng, Jun Huang, Bing Jiang
Pages: 597-604
Published online on: 27 December 2016

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Article Open Access

Expression and clinical significance of C14orf166 in esophageal squamous cell carcinoma

Yan‑Wu Zhou, Rong Li, Chao‑Jun Duan, Yang Gao, Yuan‑Da Cheng, Zhi‑Wei He, Jun‑Xian Zeng, Chun‑Fang Zhang
Pages: 605-612
Published online on: 16 December 2016

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Article Open Access

Effect of Yi Guan Jian decoction on differentiation of bone marrow mesenchymalstem cells into hepatocyte-like cells in dimethylnitrosamine-induced liver cirrhosis in mice Corrigendum in /10.3892/mmr.2021.12448

Yan Xiang, Bing‑Yao Pang, Yuan Zhang, Qiao‑Ling Xie, Ying Zhu, Ai‑Jing Leng, Long‑Qing Lu, Hai‑Long Chen
Pages: 613-626
Published online on: 29 December 2016

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Article Open Access

Fas expression is downregulated in gastric cancer

Xuming Wang, Zhengqi Fu, Ying Chen, Lijiang Liu
Pages: 627-634
Published online on: 14 December 2016

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Article Open Access

Dexmedetomidine may upregulate the expression of caveolin‑1 in lung tissues of rats with sepsis and improve the short‑term outcome

Yun Zhang, Ke Ran, Shu‑Bin Zhang, Lili Jiang, Dan Wang, Zhi‑Jian Li
Pages: 635-642
Published online on: 15 December 2016

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Article Open Access

CYP2J2 participates in atherogenesis by mediating cell proliferation, migration and foam cell formation

Rui Li, Yuan Zhang, Huacheng Yan, Hua Xiao, Yunjun Ruan, Jian Qiu, Lei Shi
Pages: 643-648
Published online on: 14 December 2016

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Article Open Access

Immunomodulatory effects of Pseudostellaria heterophylla (Miquel) Pax on regulation of Th1/Th2 levels in mice with atopic dermatitis

You Yeon Choi, Mi Hye Kim, Kwang Seok Ahn, Jae‑Young Um, Seok‑Geun Lee, Woong Mo Yang
Pages: 649-656
Published online on: 29 December 2016

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Article Open Access

Identification of a novel mutation in the EXT1 gene from a patient with multiple osteochondromas by exome sequencing

Guolin Hong, Xiaoyan Guo, Wei Yan, Qianqian Li, Hailing Zhao, Ping Ma, Xiao Hu
Pages: 657-664
Published online on: 29 December 2016

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Article Open Access

Pallidin protein in neurodevelopment and its relation to the pathogenesis of schizophrenia

Qing Shi, Congmei Li, Kuichen Li, Qin Liu
Pages: 665-672
Published online on: 21 December 2016

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Article Open Access

Fluoxetine protects against methamphetamine‑induced lung inflammation by suppressing oxidative stress through the SERT/p38 MAPK/Nrf2 pathway in rats

Yun Wang, Yu‑Han Gu, Ming Liu, Yang Bai, Huai‑Liang Wang
Pages: 673-680
Published online on: 23 December 2016

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Article Open Access

Antimicrobial resistance development following surgical site infections

Daniela Călina, Anca Oana Docea, Lucica Rosu, Ovidiu Zlatian, Alexandra Floriana Rosu, Florin Anghelina, Otilia Rogoveanu, Andreea Letiția Arsene, Alina Crenguța Nicolae, Cristina Manuela Drăgoi, John Tsiaoussis, Aristides M. Tsatsakis, Demetrios A. Spandidos, Nikolaos Drakoulis, Eliza Gofita
Pages: 681-688
Published online on: 13 December 2016

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Article Open Access

Tim-3 is upregulated in human colorectal carcinoma and associated with tumor progression

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Peng Zhang
Pages: 689-695
Published online on: 22 December 2016

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Article Open Access

Downregulation of mouse CCR3 by lentiviral shRNA inhibits proliferation and induces apoptosis of mouse eosinophils

Xin‑Hua Zhu, Bing Liao, Yi Xu, Ke Liu, Yun Huang, Quan‑Long Huang, Yue‑Hui Liu
Pages: 696-702
Published online on: 29 December 2016

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Article Open Access

Downregulation of the β1 adrenergic receptor in the myocardium results in insensitivity to metoprolol and reduces blood pressure in spontaneously hypertensive rats

Yun Huang, Xiao‑Li Liu, Jia Wen, Li‑Hua Huang, Yao Lu, Ru‑Jia Miao, Xing Liu, Ying Li, Xiao‑Wei Xing, Hong Yuan
Pages: 703-711
Published online on: 14 December 2016

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Article Open Access

Hyperlipidemia-induced apoptosis of hippocampal neurons in apoE(-/-) mice may be associated with increased PCSK9 expression

Xue‑Shan Zhao, Qi Wu, Juan Peng, Li‑Hong Pan, Zhong Ren, Hui‑Ting Liu, Zhi‑Sheng Jiang, Gui‑Xue Wang, Zhi‑Han Tang, Lu‑Shan Liu
Pages: 712-718
Published online on: 16 December 2016

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Article Open Access

Clinical significance of Wip1 overexpression and its association with the p38MAPK/p53/p16 pathway in NSCLC

Shize Yang, Siyuan Dong, Xiaohan Qu, Xinwen Zhong, Qigang Zhang
Pages: 719-723
Published online on: 13 December 2016

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Article Open Access

Salvianolic acid B reverses multidrug resistance in HCT‑8/VCR human colorectal cancer cells by increasing ROS levels

Piaoting Guo, Songpo Wang, Wei Liang, Wenjing Wang, Huijun Wang, Miaomiao Zhao, Xiaowei Liu
Pages: 724-730
Published online on: 14 December 2016

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Article Open Access

Identification of therapeutic targets for Parkinson's disease via bioinformatics analysis

Na Dong, Xueqing Zhang, Qingjun Liu
Pages: 731-735
Published online on: 14 December 2016

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Article Open Access

Safety and toxicology of the intravenous administration of Ang2‑siRNA plasmid chitosan magnetic nanoparticles

Xiuying Shan, Tingting Xu, Zhaoliang Liu, Xuefeng Hu, Yan‑Ding Zhang, Biao Wang
Pages: 736-742
Published online on: 29 December 2016

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Article Open Access

High expression of B23 is associated with tumorigenesis and poor prognosis in bladder urothelial carcinoma

Haiping Wang, Gangjun Yuan, Bai Zhao, Yakun Zhao, Yu Qiu
Pages: 743-749
Published online on: 13 December 2016

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Article Open Access

Genome-wide association scans for idiopathic osteonecrosis of the femoral head in a Korean population

Seung‑Hoon Baek, Kang‑Il Kim, Kyung‑Sik Yoon, Tae‑Ho Kim, Shin‑Yoon Kim
Pages: 750-758
Published online on: 14 December 2016

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Article Open Access

The development and biological characteristics of a novel potentially radioresistant inbred mouse strain

Qin Wang, Liqing Du, Yan Wang, Chang Xu, Zhijuan Sun, Yue Fu, Bing Yang, Yueying Wang, Chuanjie Mu, Saijun Fan, Lu Cai, Takanori Katsube, Qiang Liu
Pages: 759-767
Published online on: 22 December 2016

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Article Open Access

Inhibiting purinergic P2X7 receptors with the antagonist brilliant blue G is neuroprotective in an intranigral lipopolysaccharide animal model of Parkinson's disease

Xin‑Hong Wang, Xin Xie, Xiao‑Guang Luo, Hong Shang, Zhi‑Yi He
Pages: 768-776
Published online on: 23 December 2016

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Article Open Access

The effect of inhaled inactived Mycobacterium phlei as a treatment for asthma

Moyu Ming, Chaoqian Li, Zhixi Luo, Shengqiu Lv, Qixiang Sun
Pages: 777-783
Published online on: 29 December 2016

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Article Open Access

Nicotinamide phosphoribosyltransferase inhibits receptor activator of nuclear factor-κB ligand-induced osteoclast differentiation in vitro

Jong Min Baek, Sung‑Jun Ahn, Yoon‑Hee Cheon, Myeung Su Lee, Jaemin Oh, Ju‑Young Kim
Pages: 784-792
Published online on: 23 December 2016

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Article Open Access

Microduplication of 7q36.3 encompassing the SHH long‑range regulator (ZRS) in a patient with triphalangeal thumb‑polysyndactyly syndrome and congenital heart disease

Zhenghua Liu, Ni Yin, Lianghui Gong, Zhiping Tan, Bangliang Yin, Yifeng Yang, Cheng Luo
Pages: 793-797
Published online on: 29 December 2016

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Article

Atorvastatin alleviates renal ischemia-reperfusion injury in rats by promoting M1-M2 transition

Qi Wang, Yan‑Yan Su, Yan‑Qun Li, Yun‑Fang Zhang, Shen Yang, Jie‑Lin Wang, Hong‑Yan Li
Pages: 798-804
Published online on: 23 December 2016

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Article

Inhibition of TLR4 protects rat islets against lipopolysaccharide-induced dysfunction Retraction in /10.3892/mmr.2025.13622

Xiao Wang, Qin Min Ge, Fan Bian, Yan Dong, Chun Mei Huang
Pages: 805-812
Published online on: 30 December 2016

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Article

SIRT1‑mediated regulation of oxidative stress induced by Pseudomonas aeruginosa lipopolysaccharides in human alveolar epithelial cells

Xiaoli Liu, Tuo Yang, Tieying Sun, Kuiqing Shao
Pages: 813-818
Published online on: 14 December 2016

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Article

Short hairpin RNA directed against β-catenin inhibits prostate cancer growth and invasion in vitro

Jiahui Zhao, Chunting Wu, Yong Luo, Yongguang Jiang
Pages: 819-824
Published online on: 22 December 2016

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Article

Quercetin alleviates cell apoptosis and inflammation via the ER stress pathway in vascular endothelial cells cultured in high concentrations of glucosamine

Xiaxia Cai, Lei Bao, Ye Ding, Xiaoqian Dai, Zhaofeng Zhang, Yong Li
Pages: 825-832
Published online on: 15 December 2016

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Article

Influence of microRNA‑34a on proliferation, invasion and metastasis of HCT116 cells

Chunyan Li, Shuming Lu, Yingyan Wang, Shibin Guo, Tianyu Zhao, Xiaosheng Wang, Bo Song
Pages: 833-838
Published online on: 29 December 2016

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Article

Hypomethylation of Agtrap is associated with long-term inhibition of left ventricular hypertrophy in prehypertensive losartan-treated spontaneously hypertensive rats

Ting‑Jun Wang, Gui‑Li Lian, Xu Lin, Hong‑Bin Zhong, Chang‑Sheng Xu, Hua‑Jun Wang, Liang‑Di Xie
Pages: 839-846
Published online on: 14 December 2016

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Article

Correlative analyses of the expression levels of PIAS3, p-SHP2, SOCS1 and SOCS3 with STAT3 activation in human astrocytomas

Li‑Hong Liu, Hong Li, Xiao‑Xin Cheng, Qing‑You Kong, Xiao‑Yan Chen, Mo‑Li Wu, Yan Li, Jia Liu, Cong Li
Pages: 847-852
Published online on: 28 December 2016

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Article

Mechanical stress influences the viability and morphology of human parametrial ligament fibroblasts

Ming Hu, Li Hong, Shasha Hong, Jie Min, Yang Zhao, Qing Yang, Qifan Zhang, Jianming Tang, Yang Li
Pages: 853-858
Published online on: 15 December 2016

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Article

Combined toxicity and underlying mechanisms of a mixture of eight heavy metals

Qi Zhou, Yuanliang Gu, Xia Yue, Guochuan Mao, Yafei Wang, Hong Su, Jin Xu, Hongbo Shi, Baobo Zou, Jinshun Zhao, Renyuan Wang
Pages: 859-866
Published online on: 29 December 2016

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Article

Identification of key genes in colorectal cancer using random walk with restart

Xiaofeng Cui, Kexin Shen, Zhongshi Xie, Tongjun Liu, Haishan Zhang
Pages: 867-872
Published online on: 19 December 2016

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Article

Three-dimensional simulated microgravity culture improves the proliferation and odontogenic differentiation of dental pulp stem cell in PLGA scaffolds implanted in mice

Yanping Li, Lina He, Shuang Pan, Lin Zhang, Weiwei Zhang, Hong Yi, Yumei Niu
Pages: 873-878
Published online on: 14 December 2016

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Article

Effects of Lycium barbarum polysaccharides on the damage to human endometrial stromal cells induced by hydrogen peroxide

Tieying Shan, Tieqiang Shan, Fengli Liu, Haiping Zheng, Guiying Li
Pages: 879-884
Published online on: 28 December 2016

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Article

Inhibitory effects of resveratrol on the adhesion, migration and invasion of human bladder cancer cells

Yu Bai, Hong Yang, Guoying Zhang, Libing Hu, Yonghong Lei, Yang Qin, Yong Yang, Qilin Wang, Ruiqian Li, Qiqi Mao
Pages: 885-889
Published online on: 15 December 2016

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Article

Low‑molecular weight fucoidan inhibits the differentiation of osteoclasts and reduces osteoporosis in ovariectomized rats

Xin Jin, Liguo Zhu, Xiulan Li, Jian Jia, Yang Zhang, Xiaolei Sun, Jianxiong Ma, Zhaojie Liu, Xinlong Ma
Pages: 890-898
Published online on: 20 December 2016

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Article

AMPK activators suppress breast cancer cell growth by inhibiting DVL3-facilitated Wnt/β-catenin signaling pathway activity

Yu‑Feng Zou, Chun‑Wei Xie, Shi‑Xin Yang, Jian‑Ping Xiong
Pages: 899-907
Published online on: 29 December 2016

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Article

Modulation of low shear stress‑induced eNOS multi‑site phosphorylation and nitric oxide production via protein kinase and ERK1/2 signaling

Xiangquan Kong, Xinliang Qu, Bing Li, Zhimei Wang, Yuelin Chao, Xiaomin Jiang, Wen Wu, Shao‑Liang Chen
Pages: 908-914
Published online on: 20 December 2016

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Article

Expression of MMPs is dependent on the activity of mitogen-activated protein kinase in chondrosarcoma

Min Yao, Xiaomei Wang, Yufeng Zhao, Xiaomeng Wang, Feng Gao
Pages: 915-921
Published online on: 27 December 2016

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Article

MicroRNA‑375 inhibits oral squamous cell carcinoma cell migration and invasion by targeting platelet‑derived growth factor‑A

Zheng‑Hao Cao, Jing‑Liang Cheng, Yong Zhang, Chun‑Xiao Bo, Yan‑Liang Li
Pages: 922-928
Published online on: 19 December 2016

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Article

Scutellarin suppresses growth and causes apoptosis of human colorectal cancer cells by regulating the p53 pathway

Ning Yang, Yuying Zhao, Zhipeng Wang, Yu Liu, Yanqiao Zhang
Pages: 929-935
Published online on: 28 December 2016

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Article Open Access

Identification of a missense mutation of COL3A1 in a Chinese family with atypical Ehlers-Danlos syndrome using targeted next-generation sequencing

Wenwen Zhang, Qian Han, Min Zhou, Feng Ran, Tong Qiao, Long Yi, Changjian Liu, Zhao Liu
Pages: 936-940
Published online on: 29 December 2016

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Article

Digitoxin synergizes with sorafenib to inhibit hepatocelluar carcinoma cell growth without inhibiting cell migration

Yijun Xiao, Wei Yan, Libin Guo, Chen Meng, Bin Li, Henrique Neves, Peng‑Chen Chen, Ling Li, Yide Huang, Hang Fai Kwok, Yao Lin
Pages: 941-947
Published online on: 30 December 2016

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Article

MicroRNA‑152 inhibits cell proliferation, migration and invasion by directly targeting MAFB in nasopharyngeal carcinoma Retraction in /10.3892/mmr.2023.12960

Yan Li, Daliu Min, Kai Wang, Shankai Yin, Hongliang Zheng, Liangfa Liu
Pages: 948-956
Published online on: 19 December 2016

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Article

Methyl jasmonate induces the apoptosis of human colorectal cancer cells via downregulation of EZH2 expression by microRNA‑101

Zheng Peng, Yong Zhang
Pages: 957-962
Published online on: 20 December 2016

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Article

PROX1 promotes human glioblastoma cell proliferation and invasion via activation of the nuclear factor-κB signaling pathway

Xuchang Xu, Xuefeng Wan, Xinting Wei
Pages: 963-968
Published online on: 27 December 2016

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Article

TGF-β1 mimics the effect of IL-4 on the glycosylation of IgA1 by downregulating core 1 β1, 3-galactosyltransferase and Cosmc

Jun Xiao, Manting Wang, Dawei Xiong, Ying Wang, Qiuyue Li, Jing Zhou, Qinkai Chen
Pages: 969-974
Published online on: 29 December 2016

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Article

Antinociceptive effects of fucoidan in rat models of vincristine-induced neuropathic pain

Chuanyin Hu, Yun‑Tao Zhao, Guoping Zhang, Ming‑Feng Xu
Pages: 975-980
Published online on: 23 December 2016

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Therapeutic mechanisms of ibuprofen, prednisone and betamethasone in osteoarthritis

Fenglong Sun, Yaohua Zhang, Qiang Li
Pages: 981-987
Published online on: 22 December 2016

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Role of tRNA selenocysteine 1 associated protein 1 in the proliferation and apoptosis of cardiomyocyte‑like H9c2 cells

Meng‑Di Li, Wan‑Peng Cheng, Min‑Xia Shi, Tang‑Dong Ge, Xiao‑Lin Zheng, Dong‑Yuan Wu, Xiao‑Yan Hu, Jin‑Cheng Luo, Feng‑Lan Li, Hui Li
Pages: 988-994
Published online on: 30 December 2016

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Involvement of DJ‑1 in ischemic preconditioning‑induced delayed cardioprotection in vivo

Huan Wang, Yuan‑Yuan Li, Ling‑Yu Qiu, Yu‑Feng Yan, Zhang‑Ping Liao, He‑Ping Chen
Pages: 995-1001
Published online on: 29 December 2016

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[Corrigendum] Clinical characteristics and the identification of novel mutations of COL1A1 and COL1A2 in 61 Chinese patients with osteogenesis imperfecta

Hao Zhang, Hua Yue, Chun Wang, Weiwei Hu, Jiemei Gu, Jinwei He, Wenzhen Fu, Yunqiu Hu, Miao Li, Zhenlin Zhang
Pages: 1002-1002
Published online on: 30 December 2016

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August-2026 Volume 34 Issue 2

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Regulatory function of ten‑eleven translocation‑2 in transcriptional mechanisms of demethylated myeloma cells

Lenka Slavickova, Michaela Nemcova, Dominika Svehlova, Veronika Frybortova, Jirina Manakova, Eva Kriegova, Jiri Minarik, Katerina Smesny Trtkova
Article Number: 237
Published online on: 25 June 2026

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Mulberroside A attenuates H2O2‑induced oxidative stress and barrier dysfunction in Caco‑2 cells through Nrf2/HO‑1‑associated antioxidant signaling

Jianxin Chen, Xiufeng Huang, Xi Chen, Wenhai Jin, Dawei Lin
Article Number: 236
Published online on: 25 June 2026

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[Retracted] Puerarin promotes DUSP1 expression by regulating miR‑133a‑3p in breast cancer

Zhifeng Li, Weiwei Xu, Xiaoyan Ren, Jinhua Xu, Jianxin Chen
Article Number: 235
Published online on: 23 June 2026

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Sulforaphane attenuates cisplatin‑induced acute kidney injury by inhibiting oxidative stress, inflammation and apoptosis via regulation of NRF2

Zeyu Wu, Mengting Lu, Lei Xu, Ming Luo, Limei Shan, Hongxia Xing, Wenwen Li, Junling Qian
Article Number: 234
Published online on: 19 June 2026

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Effects of β‑hydroxybutyrate on restoring autophagic flux and mitochondrial function in macrophages exposed to oxidized low‑density lipoprotein

Weiguang Luo, Mei He, Huiling Wang
Article Number: 233
Published online on: 19 June 2026

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Genetic and molecular mechanisms of hereditary thoracic aortic aneurysm and dissection (Review)

Xiaokang Wang, Qiwen Tan, Jingcheng Xu, Yunlin Yang, Haoyue Huang, Xiaomei Teng, Weihua Wu
Article Number: 232
Published online on: 18 June 2026

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Degraded sulfated galactan derived from Gracilaria fisheri induces immunogenic cell death in MDA‑MB‑231 cells

Tawut Rudtanatip, Yada Polsan, Waraporn Sakaew, Somsuda Somintara, Jenjiralai Phanphak, Jamal El‑Abid, Kanokpan Wongprasert, Choowadee Pariwatthanakun
Article Number: 231
Published online on: 17 June 2026

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Article

Irbesartan ameliorates high‑glucose‑induced epithelial‑mesenchymal transition by downregulating the expression of NLRP3 in HK‑2 cells

Qing Deng, Xiujuan Liu, Dan Wen, Yuhua Cheng, Qing Zhao, Yu Wang, Yu Xiang, Qinkai Chen, Jinlei Lv
Article Number: 230
Published online on: 17 June 2026

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A β‑1,3‑1,6‑glucan from Aureobasidium pullulans enhances apoptotic and autophagic pathways in colorectal cancer cells

Ji-Won Park, Gyeong Mim Mun, Tae Min Jo, Ji A Shin, Takao Kuge, Hisashi Kimoto, Jin-Kyung Kim
Article Number: 229
Published online on: 16 June 2026

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Growth pattern and molecular biological analysis of primary meningioma cell cultures under different conditions

Stefan Linsler, Anna-Lena Moroldo, Walter Schulz‑Schaeffer, Ralf Ketter, Joachim Oertel, Steffi Urbschat
Article Number: 228
Published online on: 12 June 2026

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Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

Congcong Xie, Zehao Liu, Tong Chen, Hui Lu, Xiujia Zhang, Wenbo Yu, Jiaxin Zhang, Dandan Shang, Xueying Wang
Article Number: 227
Published online on: 11 June 2026

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Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

Tao Yang, Hanji Zhang, Mingjun Li, Yiming Ren, Yunbo Sun, Weiyu Hou, Mengqiang Tian
Article Number: 226
Published online on: 11 June 2026

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[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Review Open Access

Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
Published online on: 08 June 2026

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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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Correction Open Access

[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Review Open Access

Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Article Open Access

Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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Journal Cover
September-2026 Volume 34 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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