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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-December 2011 Volume 4 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Macrolides for the treatment of chronic bacterial prostatitis: An effective application of their unique pharmacokinetic and pharmacodynamic profile (Review)

G. Perletti, V. Skerk, V. Magri, A. Markotic, S. Mazzoli, M. J. Parnham, F.M. E. Wagenlehner, K. G. Naber
Pages: 1035-1044
Published online on: 25 August 2011

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Review

MALDI mass spectrometry imaging in oncology (Review)

Timo Gemoll, Uwe J. Roblick, Jens K. Habermann
Pages: 1045-1051
Published online on: 22 August 2011

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Article Open Access

Nutritional improvement of metabolic syndrome parameters in immature fructose-fed wild-type mice

J. C. Cha, V. Ivanov, M. W. Roomi, T. Kalinovsky, A. Niedzwiecki, M. Rath
Pages: 1053-1059
Published online on: 19 August 2011

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Article Open Access

Down-regulation of ghrelin receptors in the small intestine delays small intestinal transit in vagotomized rats

Cheng-Guang Yang, Wen-Cai Qiu, Zhi-Gang Wang, Song Yu, Jun Yan, Qi Zheng
Pages: 1061-1065
Published online on: 24 August 2011

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Article

A new membrane re-anchored protein originating from GPC3 against hepatoma cells HepG2

Dongye Yang, Junwen Yang, Fanggen Lu, Caihong Li, Jingbo Yang, Jieling Liang
Pages: 1067-1073
Published online on: 19 July 2011

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Article

Lentiviral vector-mediated siRNA knockdown of the YAP gene inhibits growth and induces apoptosis in the SGC7901 gastric cancer cell line

Zhou Zhou, Jin-Shui Zhu, Zhi-Peng Xu, Qiang Zhang
Pages: 1075-1082
Published online on: 28 July 2011

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Article

Colon cancer-derived factors activate NF-κB in myeloid cells via TLR2 to link inflammation and tumorigenesis

Shin Maeda, Yohko Hikiba, Kei Sakamoto, Hayato Nakagawa, Yoshihiro Hirata, Yoku Hayakawa, Masao Akanuma
Pages: 1083-1088
Published online on: 04 August 2011

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Article

p53 siRNA inhibits apoptosis of U2OS cells treated with azurin

Xiaobo Yan, Jie Feng, Zhaoming Ye, Xudong Miao, Weixu Li, Disheng Yang
Pages: 1089-1094
Published online on: 04 August 2011

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Article

Analysis of serum enzyme levels in a rabbit model of acute mesenteric ischemia

Fu-Xian Zhang, Bing-Bing Ma, Gang-Zhu Liang, Huan Zhang
Pages: 1095-1099
Published online on: 12 August 2011

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Article

Molecular characteristics of pediatric non-ependymal, non‑pilocytic gliomas associated with resistance to temozolomide

Taketo Ezaki, Hikaru Sasaki, Yuichi Hirose, Tomoru Miwa, Kazunari Yoshida, Takeshi Kawase
Pages: 1101-1105
Published online on: 25 August 2011

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Article

Anti-obesity effects of Geranium thunbergii extract via improvement of lipid metabolism in high-fat diet-induced obese mice

Yoon-Young Sung, Taesook Yoon, Won-Kyung Yang, Seung Ju Kim, Ho Kyoung Kim
Pages: 1107-1113
Published online on: 22 August 2011

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Article

Factors influencing RhoA protein distribution in the nucleus

Yueying Li, Yongchang Chen, Jin Xu
Pages: 1115-1119
Published online on: 16 August 2011

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Article

VEGF expression in mesenchymal stem cells promotes bone formation of tissue-engineered bones

Boling Liu, Xihai Li, Guiqing Liang, Xianxiang Liu
Pages: 1121-1126
Published online on: 16 August 2011

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Article

Association between gene polymorphism of CD14-159 (C/T) and allergic asthma

Song-Quan Wu, Kai-Bo Zhang, Hai-Quan Chen, Zhi‑Gang Zhao, Guang-Li Wang, Cong Chen
Pages: 1127-1130
Published online on: 12 August 2011

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Article

Zinc finger protein HZF1 promotes K562 cell proliferation by interacting with and inhibiting INCA1

Xiao-Bo Li, Jing Chen, Min-Jie Deng, Fang Wang, Zhan-Wen Du, Jun-Wu Zhang
Pages: 1131-1137
Published online on: 22 August 2011

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Article

Clinical significance of the expression of DNA methyltransferase proteins in gastric cancer

Jian Yang, Xiaowei Wei, Qingxiang Wu, Zhi Xu, Dongying Gu, Yan Jin, Yue Shen, Huaying Huang, Hong Fan, Jinfei Chen
Pages: 1139-1143
Published online on: 31 August 2011

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Article

Cyclooxygenase mediates cardioprotection of angiotensin-(1-7) against ischemia/reperfusion-induced injury through the inhibition of oxidative stress

Xinxue Liao, Lichun Wang, Chuntao Yang, Jiangui He, Xiuyu Wang, Ruixian Guo, Aiping Lan, Xiaobian Dong, Zhanli Yang, Huaqiao Wang, Jianqiang Feng, Hong Ma
Pages: 1145-1150
Published online on: 23 August 2011

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Article

The role of neuregulin4 and HER4 in gastrointestinal malignant lymphoma

Masahide Ebi, Hiromi Kataoka, Takaya Shimura, Yoshikazu Hirata, Takashi Mizushima, Tsutomu Mizoshita, Mamoru Tanaka, Hironobu Tsukamoto, Keiji Ozeki, Satoshi Tanida, Takeshi Kamiya, Hiroshi Inagaki, Takashi Joh
Pages: 1151-1155
Published online on: 26 July 2011

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Article

Induction of peroxisomal lipid metabolism in mice fed a high-fat diet

Sachi Kozawa, Ayako Honda, Naomi Kajiwara, Yasuhiko Takemoto, Tomoko Nagase, Hideki Nikami, Yukio Okano, Shigeru Nakashima, Nobuyuki Shimozawa
Pages: 1157-1162
Published online on: 17 August 2011

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Article

Nitric oxide inhibits gastric cancer cell growth through the modulation of the Akt pathway

Jianrong Sang, Yongchang Chen, Yan Tao
Pages: 1163-1167
Published online on: 15 July 2011

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Article

Osteopontin regulates growth and migration of human nasopharyngeal cancer cells

Guang Yang, Yan Zhang, Jing Wu, Jianjun Xiong, Haixia Deng, Jiali Wang, Changfu Yang, Zhenyu Zhu
Pages: 1169-1173
Published online on: 21 July 2011

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Article

Assessment of the beneficial loci and prognostic implications of microsatellite instability in gastric carcinoma

Ji Un Kang, Sun Hoe Koo
Pages: 1175-1181
Published online on: 26 July 2011

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Article

Testosterone suppresses oxidative stress via androgen receptor-independent pathway in murine cardiomyocytes

Li Zhang, Saizhu Wu, Yunjun Ruan, Lei Hong, Xiaowen Xing, Wenyan Lai
Pages: 1183-1188
Published online on: 22 July 2011

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Article

Synergistic antitumor effect of β-elemene and etoposide is mediated via induction of cell apoptosis and cell cycle arrest in non-small cell lung carcinoma cells

Fan Zhang, Ling Xu, Xiujuan Qu, Mingfang Zhao, Bo Jin, Jian Kang, Yunpeng Liu, Xuejun Hu
Pages: 1189-1193
Published online on: 20 July 2011

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Article

5-Lipoxygenase contributes to the progression of hepatocellular carcinoma

Xi-Ming Xu, Jun-Jian Deng, Guang-Jin Yuan, Fang Yang, Hong-Ting Guo, Miao Xiang, Wei Ge, Yao-Gui Wu
Pages: 1195-1200
Published online on: 08 August 2011

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Article

Non-small cell lung cancer invasion and metastasis promoted by MMP-26

Yang Zhang, Hang Zhao, Yeling Wang, Yong Lin, Yan  Tan, Xuexun Fang, Lianwen Zheng
Pages: 1201-1209
Published online on: 26 July 2011

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Article

Resveratrol interferes with N-nitrosodiethylamine-induced hepatocellular carcinoma at early and advanced stages in male Wistar rats

Devaraja Rajasekaran, Jayasudha Elavarasan, Murugan Sivalingam, Ekambaram  Ganapathy, Akhilandeeswari Kumar, K. Kalpana, Dhanapal Sakthisekaran
Pages: 1211-1217
Published online on: 16 August 2011

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Article

Association of APOE polymorphisms and insulin resistance with TCM syndromes in type 2 diabetes patients with macroangiopathy

Yi-qiang Xie, Hua Wang, Yue-ping Wu, De-hui Yin, Zhuan-suo Wang, Yong-hao Huang
Pages: 1219-1223
Published online on: 05 August 2011

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Article

Effects of osteopontin downregulation on the growth of prostate cancer PC-3 cells

Jie Zheng, Zhi-Bo Hou, Nan-Lin Jiao
Pages: 1225-1231
Published online on: 12 August 2011

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Article

Up-regulation of CD44 expression by interleukin-13 in a murine model of asthma

Li Xue, Hongyan Liang, Xiaofeng Jiang
Pages: 1233-1237
Published online on: 12 August 2011

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Article

Polymorphisms in estrogen receptor-α are associated with idiopathic female infertility

Jiu-Wei Du, Xin-Rong Tao, Ke-Yi Xu, Li-Yi Fang, Xin-Lan Qi
Pages: 1239-1242
Published online on: 12 August 2011

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Article

Cbl-regulated Akt and ERK signals are involved in β-elemene-induced cell apoptosis in lung cancer cells

Lei Li, Ling Xu, Xiujuan Qu, Mingfang Zhao, Ping Yu, Jian Kang, Yunpeng Liu, Xuejun Hu
Pages: 1243-1246
Published online on: 11 August 2011

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Article

The expression of human papillomavirus type 16 (HPV16 E7) induces cell cycle arrest and apoptosis in radiation and hypoxia resistant glioblastoma cells

Sung-Ung Moon, Soo Kyoung Choi, Han Jo Kim, Kiran Kumar Bokara, Kyung Ah Park, Won Taek Lee, Jong-Eun Lee
Pages: 1247-1253
Published online on: 17 August 2011

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Article

Inhibition of the ubiquitin-proteasome system sensitizes TRAIL-resistant prostate cancer cells by up-regulation of death receptor 5

You-Jin Lee, Jae-Won Seol, Jae-Kyo Jeong, Myung-Hee Moon, Sang‑Youel  Park
Pages: 1255-1259
Published online on: 16 August 2011

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Article

RNA interference targeting NRP-1 inhibits human glioma cell proliferation and enhances cell apoptosis

Xiangyun Li, Ting Tang, Xiaozhe Lu, Houguang Zhou, Yanyan Huang
Pages: 1261-1266
Published online on: 12 August 2011

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Article

Molecular cloning and tissue distribution of a Schistosoma japonicum gene encoding AMY-1

Dong Hu, Jing Wu, Xiaoping Tang, Fengyu Hu, Yabo Yang, Jiuwei Du, Song Ye, Rongbo Zhang
Pages: 1267-1271
Published online on: 22 August 2011

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Article

DNA demethylation is superior to histone acetylation for reactivating cancer-associated genes in ovarian cancer cells

Chun-Feng Meng, Bo Su, Wei Li
Pages: 1273-1278
Published online on: 16 August 2011

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Article

NM_001013649.3 gene is down-regulated in human colorectal adenocarcinoma

Qin Jiang, Chunle Zhang, Yao Chen
Pages: 1279-1281
Published online on: 22 August 2011

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Article

Effect of Hedyotis Diffusa Willd extract on tumor angiogenesis

Jiumao Lin, Lihui Wei, Wei Xu, Zhenfeng Hong, Xianxiang Liu, Jun Peng
Pages: 1283-1288
Published online on: 31 August 2011

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Article

Highly expressed SLC35F2 in non-small cell lung cancer is associated with pathological staging

Liang Bu, Guanchao Jiang, Fan Yang, Jun Liu, Jun Wang
Pages: 1289-1293
Published online on: 24 August 2011

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Article

Investigation of vasculogenic mimicry in intracranial hemangiopericytoma

Zhen Zhang, Yun Han, Keke Zhang, Liangzhu Teng
Pages: 1295-1298
Published online on: 22 August 2011

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Article

regulation of the invasion and metastasis of human glioma cells by polypeptide N-acetylgalactosaminyltransferase 2

Jun Liu, Lingyan Yang, Meifang Jin, Lan Xu, Shiliang Wu
Pages: 1299-1305
Published online on: 22 August 2011

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Article

Effect of human cytomegalovirus infection on the expression of Hoxb2 and Hoxb4 genes in the developmental process of cord blood erythroid progenitors

Wen-Jun Liu Liu, Mei-Xian Huang, Qu-Lian Guo, Jun-Hong Chen, Han Shi
Pages: 1307-1311
Published online on: 30 August 2011

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Article

Anti-proliferative effect of an extract of the root of Polygonum multiflorum Thunb. on MCF-7 human breast cancer cells and the possible mechanisms

Hong-Sheng Chen, Yan Liu, Luo-Qiang Lin, Jin-Lu Zhao, Chun-Peng Zhang, Jun-Chao Jin, Lei Wang, Ming-Han Bai, Yi-Chong Wang, Ming Liu, Bao-Zhong Shen
Pages: 1313-1319
Published online on: 25 August 2011

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Article

Human papillomavirus prevalence in women with normal cytology and with cervical cancer in Natal, Brazil

José Veríssimo Fernandes, Rosely de Vasconcellos Meissner, Maria Goretti Freire Carvalho, Thales Allyrio Araújo de Medeiros Fernandes, Paulo Roberto Medeiros Azevedo, Judson Weber Veríssimo de Azevedo, Josélio Maria Galvão de Araújo
Pages: 1321-1326
Published online on: 01 September 2011

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Article

The novel selenium heteropoly compound (NH4)4H4[Se2Mo2V4O24]·7H2O induces apoptosis of K562 cells

Junying Yang, Xianguang Yang, Jinyu Fan, Qingqing Zhao, Cunshuan Xu
Pages: 1327-1332
Published online on: 01 September 2011

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Article

Establishment and evaluation of three necrotizing enterocolitis models in premature rats

Wei Zhou, Xiao-Hui Zheng, Xiao Rong, Long-Guang Huang
Pages: 1333-1338
Published online on: 02 September 2011

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

ISX promotes tumor migration and invasion in lung cancer by upregulating COL1A1 in vitro

Yihe Ma, Ye Chen, Yuhui Liang, Yun Huang, Miao Gong, Lifeng Tian, Xiaojun Xiao, Jingyan Liu, Qinmiao Huang
Article Number: 77
Published online on: 31 December 2025

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Article Open Access

Role and mechanism of miR‑222‑5p in endothelial cell apoptosis

Shimeng Wang, Boxin Zhao, Ying Cui, Lin Gui, Jingyao Fan, Lijuan Huang
Article Number: 76
Published online on: 31 December 2025

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Expression of Concern Open Access

[Expression of Concern] MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA

Shijuan Zhan, Chunfeng Wang, Fangqing Yin
Article Number: 75
Published online on: 22 December 2025

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Article Open Access

Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress

Qian-Qi Qiu, Na Zhang, Ying-Yi Xu, Jing-Wen Qin, Gao-Feng Yu, Xing-Rong Song
Article Number: 74
Published online on: 22 December 2025

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Article Open Access

ST3Gal1 modulates intestinal barrier function and impacts human ulcerative colitis

Yin Tian, Yun Liu, Yangyang Shang, Lijian Ran, Li Liu, Rongquan Wang, Jun Ye
Article Number: 73
Published online on: 18 December 2025

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Article Open Access

Mechanistic study of miR‑369‑3p in regulating the Wnt/β‑catenin signaling pathway via targeting SPTBN1 in inflammatory response and bone destruction of rheumatoid arthritis

Aihong Wu, Yuan Wang, Feifei Liu, Zhoufang Cao, Shuhui Du, Mengyu Sun
Article Number: 72
Published online on: 18 December 2025

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Article Open Access

CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation

Qingbo Shao, Ji Zhang, Huaying Wang
Article Number: 71
Published online on: 17 December 2025

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Expression of Concern Open Access

[Expression of Concern] Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells

Feng He, Xiu-Mei Cheng, Wen-Long Gu
Article Number: 70
Published online on: 17 December 2025

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Article Open Access

Aggravated effects of human parvovirus B19 NS1 protein on bleomycin‑induced pulmonary fibrosis

Tsai-Ching Hsu, Chih-Chen Tzang, Chia-Wei Kuo, Zhi-Han Wen, Der-Yuan Chen, Bor-Show Tzang
Article Number: 69
Published online on: 16 December 2025

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Review Open Access

Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review)

Pai Zhang, Yabin Cui, Chunyan Liu, Chengji Cui, Shoulin Zhang, Yue Zhang, Fan Li
Article Number: 68
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li
Article Number: 67
Published online on: 15 December 2025

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Review Open Access

Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review)

Ziling Qin, Ranran Chen, Dianrong Song
Article Number: 66
Published online on: 11 December 2025

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Review Open Access

Gut microbiota as a multifaceted modulator of prostate cancer: Mechanistic insights, therapeutic opportunities and clinical challenges (Review)

Zhenming Hao, Yongqiang Xie, Ru Zhang, Hui Sang, Luxi Li, Yulin Liu, Jinbo Hu, Jijun Wang, Keqiang Chai, Qiang Zhao
Article Number: 65
Published online on: 11 December 2025

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Expression of Concern Open Access

[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 64
Published online on: 10 December 2025

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Review Open Access

Influence and treatment of insulin receptor substrate/PI3K/Akt‑mediated insulin resistance in diabetes mellitus (Review)

Weikang Tang, Huixia Liu, Xuan Li, Siyao Deng, Changyu Gao
Article Number: 63
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA ANRIL knockdown suppresses apoptosis and pro‑inflammatory cytokines while enhancing neurite outgrowth via binding microRNA‑125a in a cellular model of Alzheimer’s disease

Bingling Zhou, Lijuan Li, Xin Qiu, Jiashun Wu, Lei Xu, Wei Shao
Article Number: 62
Published online on: 08 December 2025

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Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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Article Open Access

ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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March-2026 Volume 33 Issue 3

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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