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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2013 Volume 8 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Role of PPARs in inflammatory processes associated with metabolic syndrome (Review)

Eduardo Fuentes, Luis Guzmán-Jofre, Rodrigo Moore-Carrasco, Iván Palomo
Pages: 1611-1616
Published online on: 07 October 2013

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Article Open Access

Large animal model for retroperitoneal lymphatic and lung metastasis

Yong‑Wen Huang, Ming‑Fei Guan, Ji‑Hong Liu, Chun‑Yan Lan, Ting Wan, Xin Huang
Pages: 1617-1622
Published online on: 10 October 2013

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Article

JNK inhibitor SP600125 enhances TGF‑β‑induced apoptosis of RBE human cholangiocarcinoma cells in a Smad‑dependent manner

Youzhi Lin, Binhao Zhang, Huifang Liang, Yulei Lu, Xi Ai, Bixiang Zhang, Xiaoping Chen
Pages: 1623-1629
Published online on: 02 October 2013

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Article

CIZ1 regulates the proliferation, cycle distribution and colony formation of RKO human colorectal cancer cells

Jing Yin, Changliang Wang, Xiaoyong Tang, Huaibin Sun, Qianqian Shao, Xigui Yang, Xun Qu
Pages: 1630-1634
Published online on: 08 October 2013

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Article

κ-carrageenan induces the disruption of intestinal epithelial Caco-2 monolayers by promoting the interaction between intestinal epithelial cells and immune cells

Hai-Yue Jiang, Feng Wang, Hai‑Min Chen, Xiao‑Jun Yan
Pages: 1635-1642
Published online on: 14 October 2013

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Article

Effects of nitrous oxide on the production of cytokines and chemokines by the airway epithelium during anesthesia with sevoflurane and propofol

Seiichiro Kumakura, Keisuke Yamaguchi, Yusuke Sugasawa, Taisuke Murakami, Toshihiro Kikuchi, Eiichi Inada, Isao Nagaoka
Pages: 1643-1648
Published online on: 21 October 2013

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Article

Lipopolysaccharide-induced apoptosis in a murine intestinal endocrine cell line by modulation of Bcl-2, Bax and caspase-3

Lei Lei, Jiao Wang, Zhen Zhang, Hua Zhang, Hong Chen, Dehong Cai
Pages: 1649-1654
Published online on: 21 October 2013

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Article Open Access

Capsaicin induces apoptosis in MG63 human osteosarcoma cells via the caspase cascade and the antioxidant enzyme system

Won Ho Cho, Hyun Joo Lee, Yoon Ji Choi, Joo Han Oh, Han Soo Kim, Hwan Seong Cho
Pages: 1655-1662
Published online on: 17 October 2013

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Article

Transforming growth factor‑β1 induces bronchial epithelial cells to mesenchymal transition by activating the Snail pathway and promotes airway remodeling in asthma

Zhao‑Chuan Yang, Ming‑Ji Yi, Ni Ran, Chong Wang, Peng Fu, Xue‑Ying Feng, Lei Xu, Zheng‑Hai Qu
Pages: 1663-1668
Published online on: 14 October 2013

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Article

Osteoprotegerin promotes the proliferation of chondrocytes and affects the expression of ADAMTS-5 and TIMP-4 through MEK/ERK signaling

Zhi-Yun Feng, Zhen-Nian He, Bin Zhang, Zhong Chen
Pages: 1669-1679
Published online on: 08 October 2013

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Article

A modified murine model based on hydrodynamic injection for the analysis of chronic human hepatitis B virus infection

Bo Qin, Chunyu Tu, Bo Zhang, Tingting He, Lijun Fu, Wenying Xu
Pages: 1677-1682
Published online on: 14 October 2013

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Article

Cigarette smoke extract induces the expression of GRP78 in A549 cells via the p38/MAPK pathway

Baimei He, Bailing Luo, Qiong Chen, Lemeng Zhang
Pages: 1683-1688
Published online on: 11 October 2013

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Article

Regulation of neuronal toxicity of β‑amyloid oligomers by surface ATP synthase

Sanli Xing, Dingzhu Shen, Chuan Chen, Jian Wang, Te Liu, Zhihua Yu
Pages: 1689-1694
Published online on: 11 October 2013

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Article

Glucose transporter-1 expression in CD133+ laryngeal carcinoma Hep-2 cells

Xiao-Hong Chen, Yang-Yang Bao, Shui-Hong Zhou, Qin-Ying Wang, Yan Wei, Jun Fan
Pages: 1695-1700
Published online on: 18 October 2013

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Article

Cortical lateralization in stroke patients measured by event‑related potentials during motor imagery

Weijun Gong, Tong Zhang, Lei Shan
Pages: 1701-1707
Published online on: 26 September 2013

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Article

Neuroprotective effect of calcitriol on ischemic/reperfusion injury through the NR3A/CREB pathways in the rat hippocampus

Jun Fu, Rui Xue, Junfeng Gu, Yun Xiao, Heying Zhong, Xuelian Pan, Ran Ran
Pages: 1708-1714
Published online on: 14 October 2013

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Article

Human hair follicle stem cell differentiation into contractile smooth muscle cells is induced by transforming growth factor-β1 and platelet-derived growth factor BB

Zhi Cheng Xu, Qun Zhang, Hong Li
Pages: 1715-1721
Published online on: 27 September 2013

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Article

Biological properties of bone marrow-derived early and late endothelial progenitor cells in different culture media

Xiu M. Guan, Min Cheng, Hong Li, Xiao D. Cui, Xin Li, Yu L. Wang, Jin L. Sun, Xiao Y. Zhang
Pages: 1722-1728
Published online on: 09 October 2013

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Article

Lysophosphatidic acid activates β‑catenin/T cell factor signaling, which contributes to the suppression of apoptosis in H19‑7 cells

Yuanjie Sun, Nam-Ho Kim, Liting Ji, Seung-Hyuk Kim, Jongho Lee, Hae Jin Rhee
Pages: 1729-1733
Published online on: 18 October 2013

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Article

A novel four-step system for screening angiogenesis inhibitors

Qin Zhou, Cui-Ling Qi, Yan Li, Xiao-Dong He, Jiang-Chao Li, Qian-Qian Zhang, Lan Tian, Ming Zhang, Zhe Han, Huiping Wang, Xuesong Yang, Li-Jing Wang
Pages: 1734-1740
Published online on: 26 September 2013

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Article

TGF-β‑induced miR10a/b expression promotes human glioma cell migration by targeting PTEN

Shihai Liu, Junfeng Sun, Qing Lan
Pages: 1741-1746
Published online on: 01 October 2013

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Article

MicroRNA and gene networks in human Hodgkin's lymphoma

Minghui Zhu, Zhiwen Xu, Kunhao Wang, Ning Wang, Mingyang Zhu, Shang Wang
Pages: 1747-1754
Published online on: 18 October 2013

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Article

Tumor necrosis factor-α induces ADAMTS-4 expression in human osteoarthritis chondrocytes

Juan Xue, Jianlong Wang, Qiang Liu, Aijing Luo
Pages: 1755-1760
Published online on: 14 October 2013

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Article

Changes of proteome components of Helicobacter pylori biofilms induced by serum starvation

Chunhong Shao, Yundong Sun, Na Wang, Han Yu, Yabin Zhou, Chunyan Chen, Jihui Jia
Pages: 1761-1766
Published online on: 04 October 2013

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Article

Soy soluble polysaccharide induces apoptosis in HCT‑116 human colon cancer cells via reactive oxygen species generation

Yu‑Jin Ko, Jin‑Woo Jeong, Yung‑Hyun Choi, Chung‑Ho Ryu
Pages: 1767-1772
Published online on: 14 October 2013

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Article

Peroxisome proliferator‑activated receptor γ2 Pro12Ala (rs1801282) polymorphism and breast cancer susceptibility: A meta‑analysis

Qunxia Mao, Huilin Guo, Linggen Gao, Hongwei Wang, Xu Ma
Pages: 1773-1778
Published online on: 16 October 2013

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Article

Spectrum and frequencies of mutations in the MFN2 gene and its phenotypical expression in Czech hereditary motor and sensory neuropathy type II patients

Dana Šafka Brožková, Jan Posádka, Petra Laššuthová, Radim Mazanec, Jana Haberlová, Dana Šišková, Iva Sakmaryová, Jana Neupauerová, Pavel Seeman
Pages: 1779-1784
Published online on: 14 October 2013

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Article

Cytotoxic T‑lymphocyte-associated antigen‑4 polymorphisms and susceptibility to cervical cancer: A meta‑analysis

Hao Qiu, Weifeng Tang, Pengfei Yin, Feng Cheng, Lixin Wang
Pages: 1785-1794
Published online on: 11 October 2013

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Article Open Access

ADAM33 polymorphisms are associated with asthma and a distinctive palm dermatoglyphic pattern

Weilin Xue, Wei Han, Zhao-Shan Zhou
Pages: 1795-1800
Published online on: 14 October 2013

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Article

Altered expression of pannexin proteins in patients with temporal lobe epilepsy

Ting Jiang, Hongyu Long, Yan Ma, Lili Long, Yi Li, Feng Li, Pinting Zhou, Chunyun Yuan, Bo Xiao
Pages: 1801-1806
Published online on: 18 October 2013

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Article

Canonical Wnt signaling activates miR-34 expression during osteoblastic differentiation

Masato Tamura, Maki Uyama, Yuri Sugiyama, Mari Sato
Pages: 1807-1811
Published online on: 04 October 2013

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Article

Role of tissue transglutaminase and effect of cantharidinate in human colorectal cancer

Lan‑Lan Yang, Chong‑Yang Liang, Tian‑Cheng Lu, Chen‑Yang Zhi, Bin Liu, Jian‑Hua Zhou, Xu‑Ming Liu, Hai‑Cheng Gao, Wei Huang
Pages: 1812-1816
Published online on: 27 September 2013

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Article

Crosstalk between monocytes and renal mesangial cells via interaction of metalloproteinases and fractalkine in diabetic nephropathy

Yanping Wang, Qiong Wei, Qiang Liu, Zheng Li, Li Zhou, Fang Zou, Yang Yuan, Zilin Sun
Pages: 1817-1823
Published online on: 25 September 2013

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Article

Induction of autophagy contributes to the myocardial protection of valsartan against ischemia‑reperfusion injury

Xiaoqian Wu, Lishan He, Yi Cai, Guiping Zhang, Yulian He, Zhijia Zhang, Xiaoen He, Yanhua He, Genshui Zhang, Jiandong Luo
Pages: 1824-1830
Published online on: 30 September 2013

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Article

Rosiglitazone alleviates injury in rats with adenine‑induced chronic kidney disease

Ying Huang, Yan Lei, Zhihua Zheng, Xiaohua Wang, Mingliang Hu, Rongjun Liu, Xueqing Yu
Pages: 1831-1835
Published online on: 08 October 2013

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Article

Brain-derived neurotrophic factor expression in dorsal root ganglia of a lumbar spinal stenosis model in rats

Qinliang Li, Yi Liu, Zhaoming Chu, Jinchuan Chen, Fenglei Dai, Xiaorong Zhu, Ankang Hu, Cai Yun
Pages: 1836-1844
Published online on: 11 October 2013

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Article

Association of paraoxonase gene polymorphisms with diabetic nephropathy and retinopathy

Jun Wang, Ming Ming Yang, Shi Song Rong, Tsz Kin Ng, Yan Bo Li, Xiao Min Liu
Pages: 1845-1851
Published online on: 02 October 2013

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Article

Cytoprotective effect of bioactive sea buckthorn extract on paraquat-exposed A549 cells via induction of Nrf2 and its downstream genes

Biswajit Podder, Yong-Sik Kim, Ho-Yeon Song
Pages: 1852-1860
Published online on: 16 October 2013

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Article

Interleukin-1β upregulates matrix metalloproteinase-13 gene expression via c-Jun N-terminal kinase and p38 MAPK pathways in rat hepatic stellate cells

Ning Tang, Ya-Ping Zhang, Wang Ying, Xi-Xian Yao
Pages: 1861-1865
Published online on: 10 October 2013

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Article

Realgar induces apoptosis in the chronic lymphocytic leukemia cell line MEC‑1

Xinyu Liu, Xianglu Li, Ling Wang, Xiao Lv, Na Chen, Peipei Li, Kang Lu, Xin Wang
Pages: 1866-1870
Published online on: 14 October 2013

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Article

Expression of neuronal protein Kidins220/ARMS in the spleen and peripheral blood of mice following airway allergen challenge

Ning Li, Xu Dong, Chang Yang, Yuli Liu, Xiuqin Ni
Pages: 1871-1875
Published online on: 14 October 2013

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Article

Exosomes derived from Rab27a‑overexpressing tumor cells elicit efficient induction of antitumor immunity

Wenhai Li, Deguang Mu, Feng Tian, Yunsheng Hu, Tao Jiang, Yong Han, Jiakuan Chen, Guoliang Han, Xiaofei Li
Pages: 1876-1882
Published online on: 18 October 2013

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Article

Icaritin reverses multidrug resistance of HepG2/ADR human hepatoma cells via downregulation of MDR1 and P‑glycoprotein expression

Li Sun, Weigang Chen, Lili Qu, Jie Wu, Jin Si
Pages: 1883-1887
Published online on: 18 October 2013

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Correction Open Access

[Corrigendum] Polymorphisms in the NLRP3 gene and risk of primary gouty arthritis

Dong-Mei Meng, Yu-Jiao Zhou, Luan Wang, Wei Ren, Ling-Ling Cui, Lin Han, Zheng-Hai Qu, Chang-Gui Li, Jia-Jun Zhao
Pages: 1888-1888
Published online on: 22 October 2013

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Journal Cover
January-2026 Volume 33 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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Article Open Access

FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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Article Open Access

NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Article Open Access

Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

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Review Open Access

Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Article Open Access

Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

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Article Open Access

TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

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Article Open Access

CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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Article Open Access

High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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Correction Open Access

[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Article Open Access

Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Article Open Access

Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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Article Open Access

CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Article Open Access

Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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Retraction Open Access

[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Review Open Access

Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Review Open Access

Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Review Open Access

Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Review Open Access

Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Article Open Access

Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

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Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
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Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
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Role of ubiquitin‑proteasome system in preeclampsia (Review)

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Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

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Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
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Published online on: 31 October 2025

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Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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