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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2013 Volume 8 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Role of PPARs in inflammatory processes associated with metabolic syndrome (Review)

Eduardo Fuentes, Luis Guzmán-Jofre, Rodrigo Moore-Carrasco, Iván Palomo
Pages: 1611-1616
Published online on: 07 October 2013

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Article Open Access

Large animal model for retroperitoneal lymphatic and lung metastasis

Yong‑Wen Huang, Ming‑Fei Guan, Ji‑Hong Liu, Chun‑Yan Lan, Ting Wan, Xin Huang
Pages: 1617-1622
Published online on: 10 October 2013

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Article

JNK inhibitor SP600125 enhances TGF‑β‑induced apoptosis of RBE human cholangiocarcinoma cells in a Smad‑dependent manner

Youzhi Lin, Binhao Zhang, Huifang Liang, Yulei Lu, Xi Ai, Bixiang Zhang, Xiaoping Chen
Pages: 1623-1629
Published online on: 02 October 2013

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Article

CIZ1 regulates the proliferation, cycle distribution and colony formation of RKO human colorectal cancer cells

Jing Yin, Changliang Wang, Xiaoyong Tang, Huaibin Sun, Qianqian Shao, Xigui Yang, Xun Qu
Pages: 1630-1634
Published online on: 08 October 2013

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Article

κ-carrageenan induces the disruption of intestinal epithelial Caco-2 monolayers by promoting the interaction between intestinal epithelial cells and immune cells

Hai-Yue Jiang, Feng Wang, Hai‑Min Chen, Xiao‑Jun Yan
Pages: 1635-1642
Published online on: 14 October 2013

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Article

Effects of nitrous oxide on the production of cytokines and chemokines by the airway epithelium during anesthesia with sevoflurane and propofol

Seiichiro Kumakura, Keisuke Yamaguchi, Yusuke Sugasawa, Taisuke Murakami, Toshihiro Kikuchi, Eiichi Inada, Isao Nagaoka
Pages: 1643-1648
Published online on: 21 October 2013

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Article

Lipopolysaccharide-induced apoptosis in a murine intestinal endocrine cell line by modulation of Bcl-2, Bax and caspase-3

Lei Lei, Jiao Wang, Zhen Zhang, Hua Zhang, Hong Chen, Dehong Cai
Pages: 1649-1654
Published online on: 21 October 2013

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Article Open Access

Capsaicin induces apoptosis in MG63 human osteosarcoma cells via the caspase cascade and the antioxidant enzyme system

Won Ho Cho, Hyun Joo Lee, Yoon Ji Choi, Joo Han Oh, Han Soo Kim, Hwan Seong Cho
Pages: 1655-1662
Published online on: 17 October 2013

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Article

Transforming growth factor‑β1 induces bronchial epithelial cells to mesenchymal transition by activating the Snail pathway and promotes airway remodeling in asthma

Zhao‑Chuan Yang, Ming‑Ji Yi, Ni Ran, Chong Wang, Peng Fu, Xue‑Ying Feng, Lei Xu, Zheng‑Hai Qu
Pages: 1663-1668
Published online on: 14 October 2013

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Article

Osteoprotegerin promotes the proliferation of chondrocytes and affects the expression of ADAMTS-5 and TIMP-4 through MEK/ERK signaling

Zhi-Yun Feng, Zhen-Nian He, Bin Zhang, Zhong Chen
Pages: 1669-1679
Published online on: 08 October 2013

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Article

A modified murine model based on hydrodynamic injection for the analysis of chronic human hepatitis B virus infection

Bo Qin, Chunyu Tu, Bo Zhang, Tingting He, Lijun Fu, Wenying Xu
Pages: 1677-1682
Published online on: 14 October 2013

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Article

Cigarette smoke extract induces the expression of GRP78 in A549 cells via the p38/MAPK pathway

Baimei He, Bailing Luo, Qiong Chen, Lemeng Zhang
Pages: 1683-1688
Published online on: 11 October 2013

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Article

Regulation of neuronal toxicity of β‑amyloid oligomers by surface ATP synthase

Sanli Xing, Dingzhu Shen, Chuan Chen, Jian Wang, Te Liu, Zhihua Yu
Pages: 1689-1694
Published online on: 11 October 2013

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Article

Glucose transporter-1 expression in CD133+ laryngeal carcinoma Hep-2 cells

Xiao-Hong Chen, Yang-Yang Bao, Shui-Hong Zhou, Qin-Ying Wang, Yan Wei, Jun Fan
Pages: 1695-1700
Published online on: 18 October 2013

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Article

Cortical lateralization in stroke patients measured by event‑related potentials during motor imagery

Weijun Gong, Tong Zhang, Lei Shan
Pages: 1701-1707
Published online on: 26 September 2013

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Article

Neuroprotective effect of calcitriol on ischemic/reperfusion injury through the NR3A/CREB pathways in the rat hippocampus

Jun Fu, Rui Xue, Junfeng Gu, Yun Xiao, Heying Zhong, Xuelian Pan, Ran Ran
Pages: 1708-1714
Published online on: 14 October 2013

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Article

Human hair follicle stem cell differentiation into contractile smooth muscle cells is induced by transforming growth factor-β1 and platelet-derived growth factor BB

Zhi Cheng Xu, Qun Zhang, Hong Li
Pages: 1715-1721
Published online on: 27 September 2013

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Article

Biological properties of bone marrow-derived early and late endothelial progenitor cells in different culture media

Xiu M. Guan, Min Cheng, Hong Li, Xiao D. Cui, Xin Li, Yu L. Wang, Jin L. Sun, Xiao Y. Zhang
Pages: 1722-1728
Published online on: 09 October 2013

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Article

Lysophosphatidic acid activates β‑catenin/T cell factor signaling, which contributes to the suppression of apoptosis in H19‑7 cells

Yuanjie Sun, Nam-Ho Kim, Liting Ji, Seung-Hyuk Kim, Jongho Lee, Hae Jin Rhee
Pages: 1729-1733
Published online on: 18 October 2013

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Article

A novel four-step system for screening angiogenesis inhibitors

Qin Zhou, Cui-Ling Qi, Yan Li, Xiao-Dong He, Jiang-Chao Li, Qian-Qian Zhang, Lan Tian, Ming Zhang, Zhe Han, Huiping Wang, Xuesong Yang, Li-Jing Wang
Pages: 1734-1740
Published online on: 26 September 2013

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Article

TGF-β‑induced miR10a/b expression promotes human glioma cell migration by targeting PTEN

Shihai Liu, Junfeng Sun, Qing Lan
Pages: 1741-1746
Published online on: 01 October 2013

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Article

MicroRNA and gene networks in human Hodgkin's lymphoma

Minghui Zhu, Zhiwen Xu, Kunhao Wang, Ning Wang, Mingyang Zhu, Shang Wang
Pages: 1747-1754
Published online on: 18 October 2013

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Article

Tumor necrosis factor-α induces ADAMTS-4 expression in human osteoarthritis chondrocytes

Juan Xue, Jianlong Wang, Qiang Liu, Aijing Luo
Pages: 1755-1760
Published online on: 14 October 2013

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Article

Changes of proteome components of Helicobacter pylori biofilms induced by serum starvation

Chunhong Shao, Yundong Sun, Na Wang, Han Yu, Yabin Zhou, Chunyan Chen, Jihui Jia
Pages: 1761-1766
Published online on: 04 October 2013

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Article

Soy soluble polysaccharide induces apoptosis in HCT‑116 human colon cancer cells via reactive oxygen species generation

Yu‑Jin Ko, Jin‑Woo Jeong, Yung‑Hyun Choi, Chung‑Ho Ryu
Pages: 1767-1772
Published online on: 14 October 2013

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Article

Peroxisome proliferator‑activated receptor γ2 Pro12Ala (rs1801282) polymorphism and breast cancer susceptibility: A meta‑analysis

Qunxia Mao, Huilin Guo, Linggen Gao, Hongwei Wang, Xu Ma
Pages: 1773-1778
Published online on: 16 October 2013

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Article

Spectrum and frequencies of mutations in the MFN2 gene and its phenotypical expression in Czech hereditary motor and sensory neuropathy type II patients

Dana Šafka Brožková, Jan Posádka, Petra Laššuthová, Radim Mazanec, Jana Haberlová, Dana Šišková, Iva Sakmaryová, Jana Neupauerová, Pavel Seeman
Pages: 1779-1784
Published online on: 14 October 2013

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Article

Cytotoxic T‑lymphocyte-associated antigen‑4 polymorphisms and susceptibility to cervical cancer: A meta‑analysis

Hao Qiu, Weifeng Tang, Pengfei Yin, Feng Cheng, Lixin Wang
Pages: 1785-1794
Published online on: 11 October 2013

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Article Open Access

ADAM33 polymorphisms are associated with asthma and a distinctive palm dermatoglyphic pattern

Weilin Xue, Wei Han, Zhao-Shan Zhou
Pages: 1795-1800
Published online on: 14 October 2013

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Article

Altered expression of pannexin proteins in patients with temporal lobe epilepsy

Ting Jiang, Hongyu Long, Yan Ma, Lili Long, Yi Li, Feng Li, Pinting Zhou, Chunyun Yuan, Bo Xiao
Pages: 1801-1806
Published online on: 18 October 2013

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Article

Canonical Wnt signaling activates miR-34 expression during osteoblastic differentiation

Masato Tamura, Maki Uyama, Yuri Sugiyama, Mari Sato
Pages: 1807-1811
Published online on: 04 October 2013

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Article

Role of tissue transglutaminase and effect of cantharidinate in human colorectal cancer

Lan‑Lan Yang, Chong‑Yang Liang, Tian‑Cheng Lu, Chen‑Yang Zhi, Bin Liu, Jian‑Hua Zhou, Xu‑Ming Liu, Hai‑Cheng Gao, Wei Huang
Pages: 1812-1816
Published online on: 27 September 2013

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Article

Crosstalk between monocytes and renal mesangial cells via interaction of metalloproteinases and fractalkine in diabetic nephropathy

Yanping Wang, Qiong Wei, Qiang Liu, Zheng Li, Li Zhou, Fang Zou, Yang Yuan, Zilin Sun
Pages: 1817-1823
Published online on: 25 September 2013

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Article

Induction of autophagy contributes to the myocardial protection of valsartan against ischemia‑reperfusion injury

Xiaoqian Wu, Lishan He, Yi Cai, Guiping Zhang, Yulian He, Zhijia Zhang, Xiaoen He, Yanhua He, Genshui Zhang, Jiandong Luo
Pages: 1824-1830
Published online on: 30 September 2013

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Article

Rosiglitazone alleviates injury in rats with adenine‑induced chronic kidney disease

Ying Huang, Yan Lei, Zhihua Zheng, Xiaohua Wang, Mingliang Hu, Rongjun Liu, Xueqing Yu
Pages: 1831-1835
Published online on: 08 October 2013

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Article

Brain-derived neurotrophic factor expression in dorsal root ganglia of a lumbar spinal stenosis model in rats

Qinliang Li, Yi Liu, Zhaoming Chu, Jinchuan Chen, Fenglei Dai, Xiaorong Zhu, Ankang Hu, Cai Yun
Pages: 1836-1844
Published online on: 11 October 2013

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Article

Association of paraoxonase gene polymorphisms with diabetic nephropathy and retinopathy

Jun Wang, Ming Ming Yang, Shi Song Rong, Tsz Kin Ng, Yan Bo Li, Xiao Min Liu
Pages: 1845-1851
Published online on: 02 October 2013

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Article

Cytoprotective effect of bioactive sea buckthorn extract on paraquat-exposed A549 cells via induction of Nrf2 and its downstream genes

Biswajit Podder, Yong-Sik Kim, Ho-Yeon Song
Pages: 1852-1860
Published online on: 16 October 2013

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Article

Interleukin-1β upregulates matrix metalloproteinase-13 gene expression via c-Jun N-terminal kinase and p38 MAPK pathways in rat hepatic stellate cells

Ning Tang, Ya-Ping Zhang, Wang Ying, Xi-Xian Yao
Pages: 1861-1865
Published online on: 10 October 2013

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Article

Realgar induces apoptosis in the chronic lymphocytic leukemia cell line MEC‑1

Xinyu Liu, Xianglu Li, Ling Wang, Xiao Lv, Na Chen, Peipei Li, Kang Lu, Xin Wang
Pages: 1866-1870
Published online on: 14 October 2013

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Article

Expression of neuronal protein Kidins220/ARMS in the spleen and peripheral blood of mice following airway allergen challenge

Ning Li, Xu Dong, Chang Yang, Yuli Liu, Xiuqin Ni
Pages: 1871-1875
Published online on: 14 October 2013

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Article

Exosomes derived from Rab27a‑overexpressing tumor cells elicit efficient induction of antitumor immunity

Wenhai Li, Deguang Mu, Feng Tian, Yunsheng Hu, Tao Jiang, Yong Han, Jiakuan Chen, Guoliang Han, Xiaofei Li
Pages: 1876-1882
Published online on: 18 October 2013

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Article

Icaritin reverses multidrug resistance of HepG2/ADR human hepatoma cells via downregulation of MDR1 and P‑glycoprotein expression

Li Sun, Weigang Chen, Lili Qu, Jie Wu, Jin Si
Pages: 1883-1887
Published online on: 18 October 2013

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Correction Open Access

[Corrigendum] Polymorphisms in the NLRP3 gene and risk of primary gouty arthritis

Dong-Mei Meng, Yu-Jiao Zhou, Luan Wang, Wei Ren, Ling-Ling Cui, Lin Han, Zheng-Hai Qu, Chang-Gui Li, Jia-Jun Zhao
Pages: 1888-1888
Published online on: 22 October 2013

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Journal Cover
April-2026 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Prostate‑specific membrane antigen: Molecular functions and emerging roles as a therapeutic target (Review)

Ryuta Watanabe, Tomohisa Sakaue, Noriyoshi Miura, Tadahiko Kikugawa, Takashi Saika
Article Number: 122
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑486‑5p inhibits the growth of human hypertrophic scar fibroblasts by regulating Smad2 expression

Yingying Shi, Luping Wang, Pijun Yu, Yi Liu, Wei Chen
Article Number: 121
Published online on: 25 February 2026

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Article Open Access

Prenatal lipopolysaccharide exposure programs cardiac fibrosis via dysregulating of connexin 43 in offspring rats

Yan Wen, Yao Yuan, Haigang Zhang, Ya Liu
Article Number: 120
Published online on: 24 February 2026

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Retraction Open Access

[Retracted] Upregulated microRNA‑671‑3p promotes tumor progression by suppressing forkhead box P2 expression in non‑small‑cell lung cancer

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 119
Published online on: 16 February 2026

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Article Open Access

STAT1 accelerates cutaneous melanoma progression through TUBB4A expression regulation

Rongxin Zhao, Kexin Fang, Xiaofei Zhang, Hongchao Li
Article Number: 118
Published online on: 13 February 2026

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Review Open Access

Research progress on long non‑coding RNAs in lung cancer (Review)

Renjie Pan, Chaohui Wang, Yan Tang, Fengzhou Zhong, Yan Zhuang, Qiuxia Zhao
Article Number: 117
Published online on: 12 February 2026

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Article Open Access

ULK1 activates NCOA4‑mediated ferritinophagy via the Beclin1/VPS34 complex in cardiomyocyte hypertrophy

Qianhui Zhang, Meitian Zhang, Yongsheng Liu, Pilong Shi, Hanping Qi, Man Jiang, Yonggang Cao, Hongli Sun
Article Number: 116
Published online on: 12 February 2026

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Article Open Access

miRNA‑29a inhibits the proliferation of HUVECs by regulating the ITGB1/β‑catenin/c‑Myc pathway

Qi Sun, Wenting Chen, Shan Zhang, Xinni Zhong, Yafen Wu, Yingying Qian, Lei Zhu, Ting Zhang, Wei Li
Article Number: 115
Published online on: 12 February 2026

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Article Open Access

Puerarin attenuates myocardial ischemia‑reperfusion injury by inhibiting myocardium pyroptosis via the NRF2/HO‑1 signaling pathway

Xiaoyu Zheng, Jinping Li, Tianyang Hu, Li Tan, Ding Lan, Ying Deng
Article Number: 114
Published online on: 11 February 2026

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Review Open Access

Epigenetic crossroads in intervertebral disc degeneration: Unlocking novel therapeutic avenues (Review)

Yang Hou, Lei Liu, Yongfei Guo, Jiangang Shi
Article Number: 113
Published online on: 11 February 2026

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Retraction Open Access

[Retracted] miRNA‑30a‑3p inhibits metastasis and enhances radiosensitivity in esophageal carcinoma by targeting insulin‑like growth factor 1 receptor

Yanxin Fan, Xiuhua Bian, Pudong Qian, Jing Wen, Pengwei Yan, Yanhong Luo, Jing Wu, Qian Zhang
Article Number: 112
Published online on: 09 February 2026

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Review Open Access

Circular RNAs in intervertebral disc degeneration: Current insights into mechanisms and therapeutic potentials (Review)

Luyan Wang, Ke Yang, Houjun Zhu, Dachuan Wang, Feng Wang, Xianfa Du
Article Number: 111
Published online on: 05 February 2026

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Review Open Access

T‑cadherin and its impact on human diseases (Review)

Yan Song, Xinyi Wang, Yunfei Bian
Article Number: 110
Published online on: 05 February 2026

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Review

CD20 monoclonal antibody‑rituximab for the treatment of diffuse alveolar hemorrhage in children (Review)

Xiaobo Zhang, Xiao Wu, Yan Li, Guangmin Nong
Article Number: 109
Published online on: 05 February 2026

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Article Open Access

N6‑methyladenosine reader insulin‑like growth factor 2 mRNA‑binding protein 2 promotes abnormal proliferation of colonic epithelial cells in type 2 diabetes mellitus by regulating midkine

Jieyao Li, Qingsheng Xie, Jihao Xu
Article Number: 108
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin‑induced VEGF expression

Goutam Chakraborty, Shalini Jain, Smita Kale, Remya Raja, Santosh Kumar, Rosalin Mishra, Gopal C. Kundu
Article Number: 107
Published online on: 04 February 2026

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Review Open Access

Research status and molecular mechanisms of disulfidptosis in cardiovascular diseases (Review)

Xiao Jin, Zelin Cheng, Xinyue Ding, Zongjun Liu
Article Number: 106
Published online on: 03 February 2026

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Article Open Access

Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats

Caifen Guo, Jian Li
Article Number: 105
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 104
Published online on: 02 February 2026

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Article Open Access

Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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May-2026 Volume 33 Issue 5

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Advances regarding physiological functions and mechanisms of theaflavin‑3,3'‑digallate (Review)

Teng Ma, Siwei Zhang, Miaomiao Xiao, Zhijian Ma, Junhong Guan
Article Number: 127
Published online on: 04 March 2026

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Review Open Access

Mechanisms and therapeutic potential of glycyrrhizic acid: Insights into key signaling pathways and disease modulation (Review)

Jinjin Yu, Huiheng Qu, Weicheng Xu, Yiming Fang, Nan Wang, Wei Shi
Article Number: 126
Published online on: 04 March 2026

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Review Open Access

Pyroptosis in cerebral ischemia‑reperfusion injury: Molecular mechanisms and therapeutic implications (Review)

Ze Li, Qiuli Ming, Tianyu Yang, Mengna Liu, Linpeng Fu, Jingshuang Yang, Zhaofeng Lu
Article Number: 125
Published online on: 04 March 2026

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Article Open Access

Characteristics of chromosomal instability‑related lncRNAs associated with progression and prognosis in breast cancer

Qi Chen, Hui Chen, Hui Yang, Yin Tao, Xiaolan Zhu
Article Number: 124
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Associations between Huwe1 and autophagy in rat cerebral neuron oxygen‑glucose deprivation and reperfusion injury 

Guo-Qian He, Yan Chen, Hui-Juan Liao, Wen-Ming Xu, Wei Zhang, Guo-Lin He
Article Number: 123
Published online on: 26 February 2026

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