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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-October 2003 Volume 10 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Differential expression of neuropilin-1 in malignant and benign prostatic stromal tissue

Peter J. Vanveldhuizen, Muhammad Zulfiqar, Snigdha Banerjee, Rachel Cherian, Neela K. Saxena, Amy Rabe, J. Brantley Thrasher, Sushanta K. Banerjee
Pages: 1067-1071
Published online on: 01 September 2003

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Article

Correlation of cyclooxygenase-2 pathway and VEGF expression in head and neck squamous cell carcinoma

Sung-Chul Lim, Sung-Yong Park, Nam-Yong Do
Pages: 1073-1079
Published online on: 01 September 2003

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Article

Thymidylate synthase expression as a predictor of the prognosis of curatively resected colon carcinoma in patients registered in an adjuvant immunochemotherapy clinical trial

Junichi Sakamoto, Hiroshi Hamashima, Harumi Suzuki, Katsuki Ito, Masayoshi Mai, Shigetoyo Saji, Masakazu Fukushima, Yasuyuki Matsushita, Hiroaki Nakazato
Pages: 1081-1090
Published online on: 01 September 2003

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Article

Prognostic value of p53 and Ki-67 expression in resected or biopsy specimens of bile duct carcinoma

Masateru Murakami, Tamito Sasaki, Yukio Kuwada, Souichirou Yamasaki, Kenichi Kuwahara, Kazuaki Chayama
Pages: 1091-1096
Published online on: 01 September 2003

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Article

Immunostaining of stage-specific embryonic antigen-4 in intratubular germ cell neoplasia unclassified and in testicular germ-cell tumors

Satoru Tokuyama, Seiichi Saito, Toshiko Takahashi, Chikara Ohyama, Akihiro Ito, Satoru Kanto, Makoto Satoh, Senji Hoshi, Mareyuki Endoh, Yoichi Arai
Pages: 1097-1104
Published online on: 01 September 2003

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Article

Thymidine phosphorylase expression correlates with malignant potential and anti-tumor effect of doxifluridine on gastric cancer: multivariate analysis for adjuvant chemotherapy doxifluridine vs. 5-fluorouracil

Nobuhiro Takiguchi, Rumiko Ishii, Keiji Koda, Kenji Oda, Masaru Miyazaki
Pages: 1105-1111
Published online on: 01 September 2003

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Article

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/APO2L) and its receptors expression in human squamous cell carcinoma of the oral cavity

Masakatsu Fukuda, Aya Hamao, Akio Tanaka, Munenori Kitada, Seiji Suzuki, Kaoru Kusama, Hideaki Sakashita
Pages: 1113-1119
Published online on: 01 September 2003

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Article

Adenoviral p16/CDKN2 gene transfer to malignant glioma: Role of p16 in growth, invasion, and senescence

Seung-Ki Kim, Kyu-Chang Wang, Byung-Kyu Cho, Su-Young Lim, Young-Yim Kim, Chang-Wan Oh, You-Nam Chung, Chae-Yong Kim, Choon-Taek Lee, Hyun Jib Kim
Pages: 1121-1126
Published online on: 01 September 2003

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Article

Analysis of angiogenic profiles by estimation of tumor blood flow with colored dye extraction microspheres after antiangiogenic therapy

Arifumi Iwamaru, Masazumi Watanabe, Takashi Ohtsuka, Hirohisa Horinouchi, Koichi Kobayashi
Pages: 1127-1131
Published online on: 01 September 2003

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Article

The expression of tissue factor correlates with proliferative ability in meningioma

Koichi Ishimaru, Hirofumi Hirano, Hitoshi Yamahata, Hideo Takeshima, Masaki Niiro, Jun-Ichi Kuratsu
Pages: 1133-1137
Published online on: 01 September 2003

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Article

Tissue-specific regulation of Apaf-1 expression by p53

Clement K. Ho, Jason A. Bush, Gang Li
Pages: 1139-1143
Published online on: 01 September 2003

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Article

Fas stimulation activates NF-κB in SK-Hep1 hepatocellular carcinoma cells

Hiroshi Okano, Katsuya Shiraki, Hidekazu Inoue, Tomoyuki Kawakita, Yukiko Saitou, Naoyuki Enokimura, Norihiko Yamamoto, Kazushi Sugimoto, Kazumoto Murata, Takeshi Nakano
Pages: 1145-1148
Published online on: 01 September 2003

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Article

Immunohistochemical expression of hepatocyte growth factor and c-Met/HGF receptor in benign and malignant human prostate tissue

Koh-Ichi Nakashiro, Yoshiki Hayashi, Ryoichi Oyasu
Pages: 1149-1153
Published online on: 01 September 2003

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Article

Cellular heterogeneity in long-term surviving cells isolated from eutopic endometrial, ovarian endometrioma and adenomyosis tissues

Tetsuji Tanaka, Satoko Nakajima, Naohiko Umesaki
Pages: 1155-1160
Published online on: 01 September 2003

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Article

Lymph node metastasis could be predicted by evaluation of macrophage infiltration and hsp70 expression in superficial carcinoma of the esophagus

Tsuyoshi Noguchi, Shinsuke Wada, Shinsuke Takeno, Hatsuo Moriyama, Yasuhiko Kimura, Yuzo Uchida
Pages: 1161-1164
Published online on: 01 September 2003

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Article

Correlation between occult neoplastic cells in the lymph node sinuses and recurrence in patients with Dukes' C colorectal cancer

Masaya Mukai, Shinkichi Sato, Nobukazu Komatsu, Tomomi Nishida, Kazuaki Shiba, Isao Ito, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 1165-1169
Published online on: 01 September 2003

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Article

A novel phenoxazine derivative suppresses proliferation of human endometrial adenocarcinoma cell lines, inducing G2M accumulation and apoptosis

Toshihide Nakada, Keiichi Isaka, Hirotaka Nishi, Yumi Osakabe, Takashi Shimamoto, Kazuma Ohyashiki, Akio Tomoda, Masaomi Takayama
Pages: 1171-1176
Published online on: 01 September 2003

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Article

Correlation between occult neoplastic cells in the lymph node sinuses and recurrence in patients with curatively resected Dukes' B colorectal cancer

Masaya Mukai, Shinkichi Sato, Nobukazu Komatsu, Tomomi Nishida, Kazuaki Shiba, Isao Ito, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 1177-1181
Published online on: 01 September 2003

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Article

High risk of bile duct carcinogenesis after primary resection of a congenital biliary dilatation

Akihiko Tsuchida, Kazuhiko Kasuya, Mitsufumi Endo, Hitoshi Saito, Keiichiro Inoue, Itsuro Nagae, Tasuya Aoki, Yasuhisa Koyanagi
Pages: 1183-1187
Published online on: 01 September 2003

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Article

The dog mast cell tumour as a model to study the relationship between angiogenesis, mast cell density and tumour malignancy

Girolamo Ranieri, Letizia Passantino, Rosa Patruno, Giuseppe Passantino, Felicita Jirillo, Annamaria Catino, Vittorio Mattioli, Cosmo Gadaleta, Domenico Ribatti
Pages: 1189-1193
Published online on: 01 September 2003

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Article

Mutation analysis of CTNNB1 (β-catenin) and AXIN1, the components of Wnt pathway, in cervical carcinomas

Tsung-Hsien Su, Jan-Gowth Chang, Kun-Tu Yeh, Ting-Hsu Lin, Tai-Ping Lee, Jui-Chang Chen, Cheng-Chieh Lin
Pages: 1195-1200
Published online on: 01 September 2003

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Article

Survival benefit of KRN7000 immune therapy in combination with TNP470 in hamster liver metastasis model of pancreatic cancer

Gaku Matsumoto, Shigenori Nagai, Mariko Muta, Koji Tsuruta, Atsutake Okamoto, Masakazu Toi
Pages: 1201-1206
Published online on: 01 September 2003

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Article

Occurrence of hematogenous metastasis and serum levels of thymidine phosphorylase in colorectal cancer

Masashi Haraguchi, Ko Komuta, Arifumi Akashi, Junichiro Furui, Takashi Kanematsu
Pages: 1207-1212
Published online on: 01 September 2003

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Article

Impact of vasculogenesis on solid tumor growth in a rat model

Mariko Muta, Gaku Matsumoto, Kiyoshi Hiruma, Shigehira Saji, Emi Nakashima, Masakazu Toi
Pages: 1213-1218
Published online on: 01 September 2003

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Article

Up-regulation and overproduction of DVL-1, the human counterpart of the Drosophila dishevelled gene, in cervical squamous cell carcinoma

Keiko Okino, Hisaki Nagai, Mitsuko Hatta, Takemitsu Nagahata, Koichi Yoneyama, Yujiro Ohta, Enjing Jin, Oichi Kawanami, Tsutomu Araki, Mitsuru Emi
Pages: 1219-1223
Published online on: 01 September 2003

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Article

Angiostatin expression in ovarian cancer

Hiromitsu Yabushita, Mari Noguchi, Yukihiko Obayashi, Tameko Kishida, Yasuyuki Noguchi, Keizo Sawaguchi, Masayoshi Noguchi
Pages: 1225-1230
Published online on: 01 September 2003

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Article

Comparison of immunohistochemistry and real-time reverse transcription-polymerase chain reaction to detect expression of carcinoembryonic antigen in lung cancer

Haruhiko Nakamura, Hisashi Saji, Aute Idiris, Norihito Kawasaki, Makoto Hosaka, Akihiko Ogata, Takamoto Saijo, Harubumi Kato
Pages: 1231-1235
Published online on: 01 September 2003

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Article

Clinical implications of intratumoral dendritic cell infiltration in esophageal squamous cell carcinoma

Sumiya Ishigami, Shoji Natsugoe, Masataka Matsumoto, Hiroshi Okumura, Hironori Sakita, Saburo Nakashima, Sonshin Takao, Takashi Aikou
Pages: 1237-1240
Published online on: 01 September 2003

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Article

Role of COX-2, VEGF and cyclin D1 in mammary infiltrating duct carcinoma

Sung-Chul Lim
Pages: 1241-1249
Published online on: 01 September 2003

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Article

Numerical sex chromosome aberrations in juvenile angiofibromas: Genetic evidence for an androgen-dependent tumor?

Bernhard Schick, Catharina Rippel, Christian Brunner, Volker Jung, Peter Karl Plinkert, Steffi Urbschat
Pages: 1251-1255
Published online on: 01 September 2003

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Article

Nm23-H1 expression does not predict clinical survival in colorectal cancer patients

Luisa Dusonchet, Simona Corsale, Manuela Migliavacca, Valentina Calò, Viviana Bazan, Antonella Amato, Patrizia Cammareri, Maria Serena Totaro, Valentina Agnese, Sandra Cascio, Gaspare La Rocca, Pasqua Sandra Sisto, Gabriella Dardanoni, Maria Rosaria Valerio, Nello Grassi, Stefania Latteri, Massimo Cajozzo, Maria Buscemi, Sergio Castorina, Vincenza Morello, Rosa Maria Tomasino, Nicola Gebbia, Antonio Russo
Pages: 1257-1263
Published online on: 01 September 2003

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Article

P53-induced gene 11 (PIG11) involved in arsenic trioxide-induced apoptosis in human gastric cancer MGC-803 cells

Xiao-Qui Liang, En-Hua Cao, Yan Zhang, Jing-Fen Qin
Pages: 1265-1269
Published online on: 01 September 2003

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Article

Blockade of her2/neu decreases VEGF expression but does not alter HIF-1 distribution in experimental Wilms tumor

Akiko Yokoi, Kimberly W. McCrudden, Jianzhong Huang, Eugene S. Kim, Samuel Z. Soffer, Jason S. Frischer, Anna Serur, Tamara New, Jenny Yuan, Mahesh Mansukhani, Kathleen O'Toole, Darrell J. Yamashiro, Jessica J. Kandel
Pages: 1271-1274
Published online on: 01 September 2003

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Article

The putative serine/threonine kinase gene STK15 on chromosome 20q13.2 is amplified in human gliomas

Wilfried Reichardt, Volker Jung, Christian Brunner, Alexandra Klein, Silke Wemmert, Bernd F.M. Romeike, Klaus D. Zang, Steffi Urbschat
Pages: 1275-1279
Published online on: 01 September 2003

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Article

Phenotyping of IL4-induced nuclear Stat6 activity in humans: Quantitation after gel shift assay using immortalized cell lines

Wen Jie Zhang, Jennifer L. Thompson, Michael J. Chorney, Walter A. Koltun
Pages: 1281-1288
Published online on: 01 September 2003

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Article

Comparing the efficacy and safety of fixed versus weight-based dosing of epoetin α in anemic cancer patients receiving platinum-based chemotherapy

Cristina Granetto, Sergio Ricci, Andrea Martoni, Giuseppe Pezzella, Franco Testore, Rodolfo Mattioli, Maria Lampignano, Fiorenzo Tacconi, Stella Porrozzi, Giampietro Gasparini, Giovanni Mantovani
Pages: 1289-1296
Published online on: 01 September 2003

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Article

Frequent loss of heterozygosity on chromosome 10p15, a putative telomerase repressor/senescence gene locus, in gastric cancer

Toru Hiyama, Shinji Tanaka, Hideyuki Shima, Kazuhiro Kose, Yasuhiko Kitadai, Masanori Ito, Masaharu Sumii, Masaharu Yoshihara, Fumio Shimamoto, Ken Haruma, Kazuaki Chayama
Pages: 1297-1299
Published online on: 01 September 2003

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Article

Cell growth- and P53-dependent transcriptional activity of the midkine promoter confers suicide gene expression in tumor cells

Ling Yu, Shin-Ichi Ugai, Jiyang O-Wang, Masayoshi Namba, Kenji Kadomatsu, Takashi Muramatsu, Shuichiro Matsubara, Shigeru Sakiyama, Masatoshi Tagawa
Pages: 1301-1305
Published online on: 01 September 2003

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Article

Induction of antigen specific cellular immunity by vaccination with peptides from MN/CA IX in renal cell carcinoma

Kazuhiro Shimizu, Hirotsugu Uemura, Motoyoshi Yoshikawa, Katsunori Yoshida, Yoshihiko Hirao, Kumiko Iwashima, Shinsuke Saga, Kazuhiro Yoshikawa
Pages: 1307-1311
Published online on: 01 September 2003

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Article

CD34-positive stromal cells in primary lung carcinomas

Hirofumi Nakayama, Hideaki Enzan, Maya Yamamoto, Eriko Miyazaki, Chitoshi Hidaka, Tsuneo Okumichi, Atsuo Okumichi, Hiroki Kajihara
Pages: 1313-1316
Published online on: 01 September 2003

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Article

High prevalence of hypothyroidism among patients with cutaneous melanoma

Julie A. Ellerhorst, Catherine D. Cooksley, Lyle Broemeling, Marcella M. Johnson, Elizabeth A. Grimm
Pages: 1317-1320
Published online on: 01 September 2003

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Article

Factors that influence the incidence of microscopic carcinoma in frozen and preserved specimens from patients with breast carcinoma after breast-conserving surgery

Ryungsa Kim, Akihiko Osaki, Mayumi Kaneko, Kouki Inai, Tetsuya Toge
Pages: 1321-1328
Published online on: 01 September 2003

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Article

Relationship between AgNORs, MIB-1 and oncogene expression in male breast carcinoma and papillary superficial bladder neoplasm

Achille Pich, Elena Margaria, Luigi Chiusa, Paola Bortolin, Giorgio Palestro
Pages: 1329-1335
Published online on: 01 September 2003

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Article

Survivin expression is significantly linked to the dedifferentiation of thyroid carcinoma

Yasuhiro Ito, Hiroshi Yoshida, Takashi Uruno, Keiichi Nakano, Akihiro Miya, Kaoru Kobayashi, Tamotsu Yokozawa, Fumio Matsuzuka, Nariaki Matsuura, Kennichi Kakudo, Kanji Kuma, Akira Miyauchi
Pages: 1337-1340
Published online on: 01 September 2003

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Article

Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms in patients with small cell and non-small cell lung cancer

Krzysztof Siemianowicz, Jan Gminski, Wojciech Garczorz, Natalia Slabiak, Malgorzata Goss, Marek Machalski, Helena Magiera-Molendowska
Pages: 1341-1344
Published online on: 01 September 2003

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Article

Combined use of established and novel tumour markers in the diagnosis of head and neck squamous cell carcinoma

Daniel Ayude, Gloria Gacio, María Páez De La Cadena, Estrella Pallas, Vicenta Soledad Martínez-Zorzano, Alejandro De Carlos, Francisco Javier Rodríguez-Berrocal
Pages: 1345-1350
Published online on: 01 September 2003

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Article

Rho regulates the hepatocyte growth factor/scatter factor-stimulated cell motility of human oral squamous cell carcinoma cells

Hiroyuki Kitajo, Toshiyuki Shibata, Hiroki Nagayasu, Takashi Kawano, Jun-Ichi Hamada, Tomomi Yamashita, Makoto Arisue
Pages: 1351-1356
Published online on: 01 September 2003

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Article

VHL tumor suppressor gene: its mutation and protein level in renal cell carcinoma

Hisashi Tsutsumi, Chikara Miyamoto, Yasuhiro Furuichi, Miki Yoshiike, Shiari Nozawa, Teruaki Iwamoto
Pages: 1357-1361
Published online on: 01 September 2003

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Article

Ultrastructural change due to acquired cisplatin resistance in human bladder cancer cells

Sang Jin Yoon, Inae Park, Cheol Kwak, Eunsik Lee
Pages: 1363-1367
Published online on: 01 September 2003

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Article

The copper-chelating agent, trientine, attenuates liver enzyme-altered preneoplastic lesions in rats by angiogenesis suppression

Hitoshi Yoshiji, Shigeki Kuriyama, Junichi Yoshii, Yasuhide Ikenaka, Ryuichi Noguchi, Koji Yanase, Tadashi Namisaki, Masaharu Yamazaki, Hirohisa Tsujinoue, Hiroo Imazu, Hiroshi Fukui
Pages: 1369-1373
Published online on: 01 September 2003

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Article

Reduced expression and loss of heterozygosity of the SDHD gene in colorectal and gastric cancer

Wataru Habano, Tamotsu Sugai, Shin-Ichi Nakamura, Noriyuki Uesugi, Taro Higuchi, Masanori Terashima, Saburo Horiuchi
Pages: 1375-1380
Published online on: 01 September 2003

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Article

Clinical implication of cyclin B1 in non-small cell lung cancer

Mitsuyuki Arinaga, Tsuyoshi Noguchi, Shinsuke Takeno, Masao Chujo, Takashi Miura, Yasuhiko Kimura, Yuzo Uchida
Pages: 1381-1386
Published online on: 01 September 2003

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Article

Expression of a 65 kDa oncofetal protein in human prostatic carcinoma

Margaret Hanausek, Zbigniew Walaszek, Terri M. King, Christopher I. Amos
Pages: 1387-1392
Published online on: 01 September 2003

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Article

Chromosomal imbalance in esophageal squamous cell carcinoma: 3q gain correlates with tumor progression but not prognostic significance

Tsuyoshi Noguchi, Yasuhiko Kimura, Shinsuke Takeno, Masao Chujo, Yuzo Uchida, Wolfram Mueller, Helmut E. Gabbert
Pages: 1393-1400
Published online on: 01 September 2003

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Article

Chemotherapy-induced radiation recall myositis

Marileda Indinnimeo, Claudia Cicchini, Sofia Kanakaki, Antonella Larcinese, Pietro Luigi Mingazzini
Pages: 1401-1403
Published online on: 01 September 2003

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Article

An in vitro evaluation of radiation effects of different fractionated regimens by absolute cell count beads

Qian Guo, Wei Tang, Ken-Ichi Mafune, Jinming Yu, Xianglu Liao, Min Li, Xingwu Wang, Yasuhiko Sugawara, Norihiro Kokudo, Masatoshi Makuuchi
Pages: 1405-1410
Published online on: 01 September 2003

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Article

CT findings of breast cancer with clinically complete response following neoadjuvant chemotherapy - histological correlation

Yasuhiro Ogawa, Akihito Nishioka, Kei Kubota, Shinji Kariya, Shoji Yoshida, Hironori Maeda, Yosuke Tanaka, Toshiaki Moriki, Naoshige Tochika
Pages: 1411-1415
Published online on: 01 September 2003

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Modulation of EGFR and neu expression by n-6 and n-9 high-fat diets in experimental mammary adenocarcinomas

Raquel Moral, Montserrat Solanas, Gemma García, Ramon Colomer, Eduard Escrich
Pages: 1417-1424
Published online on: 01 September 2003

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Intratumoral induction of thymidylate synthase mRNA by 5-FU in colorectal cancer patients: association with survival

Motoko Tanaka-Nozaki, Takashi Tajiri, Noritake Tanaka, Kiyonori Furukawa, Hideaki Takasaki, Kazuyasu Yoshimura, Hideyuki Suzuki, Zenya Naito, Yuuichi Sugizaki, Hans F. Merk, Brunhilde Blömeke, Shunji Kato
Pages: 1425-1429
Published online on: 01 September 2003

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E6/E7 genes of human papilloma virus type 18 induced immortalization of human fetal esophageal epithelium

Zhong-Ying Shen, Shan Cen, Li-Yan Xu, Wei-Jia Cai, Ming-Hua Chen, Jian Shen, Yi Zeng
Pages: 1431-1436
Published online on: 01 September 2003

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Topical vidarabine or 5-fluorouracil treatment against persistent HPV in genital (pre)cancerous lesions

Kenji Niwa, Keiko Tagami, Zenglin Lian, Jingchun Gao, Hideki Mori, Teruhiko Tamaya
Pages: 1437-1441
Published online on: 01 September 2003

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The increase of CD57+ T cells in the peripheral blood and their impaired immune functions in patients with advanced gastric cancer

Kentaro Chochi, Takashi Ichikura, Takashi Majima, Toshinobu Kawabata, Atsushi Matsumoto, Hidekazu Sugasawa, Nobuaki Kawarabayashi, Eiji Takayama, Hoshio Hiraide, Shuhji Seki, Hidetaka Mochizuki
Pages: 1443-1448
Published online on: 01 September 2003

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Multidetector-row CT analysis of time-dependent changes in lung fields after chest irradiation: Usefulness of precision scans

M. Imamura, S. Sawada, K. Harima, T. Shiga, M. Sougawa
Pages: 1449-1454
Published online on: 01 September 2003

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Detection of codon 61 point mutations of the K-ras gene in lung and colorectal cancers by enriched PCR

Shinichi Toyooka, Kazunori Tsukuda, Mamoru Ouchida, Motohiko Tanino, Yasuhiko Inaki, Kazuyasu Kobayashi, Masaaki Yano, Junichi Soh, Takuya Kobatake, Nobuyoshi Shimizu, Kenji Shimizu
Pages: 1455-1459
Published online on: 01 September 2003

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Protein expression of p53 and Bcl-2 has a strong correlation with radiation resistance of laryngeal squamous cell carcinoma but does not predict the radiation failure before treatment

Takenori Ogawa, Kiyoto Shiga, Masaru Tateda, Shigeru Saijo, Takashi Suzuki, Hironobu Sasano, Taeko Miyagi, Toshimitsu Kobayashi
Pages: 1461-1466
Published online on: 01 September 2003

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P38 MAPK pathway is involved in the urokinase plasminogen activator expression in human gastric SNU-638 cells

Boo A. Shin, Hyeon G. Yoo, Hong S. Kim, Mi H. Kim, Young S. Hwang, Kee O. Chay, Kee Y. Lee, Bong W. Ahn, Young D. Jung
Pages: 1467-1471
Published online on: 01 September 2003

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Follow-up CT findings of tamoxifen-induced non-alcoholic steatohepatitis (NASH) of breast cancer patients treated with bezafibrate

Yasuhiro Ogawa, Yoriko Murata, Toshiji Saibara, Akihito Nishioka, Shinji Kariya, Shoji Yoshida
Pages: 1473-1478
Published online on: 01 September 2003

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Protracted administration of weekly docetaxel in metastatic breast cancer

Katsumasa Kuroi, Hiroko Bando, Shigehira Saji, Masakazu Toi
Pages: 1479-1484
Published online on: 01 September 2003

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FDG PET in suspected recurrent and metastatic prostate cancer

Hossein Jadvar, Jacek K. Pinski, Peter S. Conti
Pages: 1485-1488
Published online on: 01 September 2003

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Cisplatin-induced ubiquitination of RNA polymerase II large subunit and suppression of induction by 7-hydroxystaurosporine (UCN-01)

Li-Ying Yang, Hong Jiang, Kelly M. Rangel, William Plunkett
Pages: 1489-1495
Published online on: 01 September 2003

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Mutational analysis of ras gene family in lung cancer in Thai

Songsak Petmitr, Duangdao Wongsommart, Panee Chaksangchaichot, Tanett Pakeetoot, Pantap Sutinont, Patay Sirivaidyapong, Anant Karalak
Pages: 1497-1501
Published online on: 01 September 2003

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Role of the host microenvironment on the expression of VEGF-subtypes in squamous cell carcinoma

Jürgen Brieger, Konstantinos Vlachtsis, Rita Gieringer, Wolf Mann
Pages: 1503-1506
Published online on: 01 September 2003

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Traditional Chinese medicine Astragalus reverses predominance of Th2 cytokines and their up-stream transcript factors in lung cancer patients

Haiming Wei, Rui Sun, Wei Xiao, Jinbo Feng, Chunyan Zhen, Xiaoqun Xu, Zhigang Tian
Pages: 1507-1512
Published online on: 01 September 2003

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Pentostatin in T-non-Hodgkin's lymphomas: Efficacy and effect on CD26+ T lymphocytes

Nam H. Dang, Fredrick B. Hagemeister, Madeleine Duvic, Jorge E. Romaguera, Anas Younes, Dan Jones, Barry Samuels, Luis E. Fayad, Barbara Pro, Felipe Samaniego, Andreas Sarris, Andre Goy, Peter McLaughlin, Ann T. Tong, Pamela L. Walker, Lili Paz Tiongson, Terry L. Smith, Yang O. Huh, Chikao Morimoto, Maria A. Rodriguez
Pages: 1513-1518
Published online on: 01 September 2003

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Aberrant CpG island methylation in neurofibromas and neurofibrosarcomas

Pilar Gonzalez-Gomez, M. Josefa Bello, Dolores Arjona, M. Eva Alonso, Jesus Lomas, Jose M. De Campos, M. Elena Kusak, Manuel Gutierrez, Jose L. Sarasa, Juan A. Rey
Pages: 1519-1523
Published online on: 01 September 2003

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Modified radiosensitivity of pancreatic cancer xenografts by farnesyl protein transferase inhibitor and MEK inhibitor

Yoshifumi Matsui, Miyako Goto, Mayumi Iwakawa, Takehide Asano, Takashi Kenmochi, Takashi Imai, Takenori Ochiai
Pages: 1525-1528
Published online on: 01 September 2003

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Effects of 1α,25-dihydroxy-vitamin D3 pretreatment and MAP kinase inhibitor PD 98059 on response of osteoblasts to prostate-derived osteoblastic factors

Ernst Ulsperger, Gerhard Hamilton, Ulrike Olszewski, Gerhard Baumgartner, Alfred Engel, Rudolf Mallinger
Pages: 1529-1534
Published online on: 01 September 2003

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High plasma YKL-40 level in patients with ovarian cancer stage III is related to shorter survival

Estrid V.S. Høgdall, Julia S. Johansen, Susanne K. Kjaer, Paul A. Price, Lise Christensen, Jan Blaakaer, Johannes E. Bock, Eva Glud, Claus K. Høgdall
Pages: 1535-1538
Published online on: 01 September 2003

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Expression and intracellular localization of Smad proteins in human endometrial cancer

Dagmara Piestrzeniewicz-Ulanska, Magdalena Brys, Andrzej Semczuk, Jerzy A. Jakowicki, Wanda M. Krajewska
Pages: 1539-1544
Published online on: 01 September 2003

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Predicting factors for collection of peripheral blood stem cells in patients with advanced germ cell tumors after cisplatin-based combination chemotherapy

Mototsugu Murakami, Hideaki Miyake, Shoji Hara, Sadao Kamidono, Isao Hara
Pages: 1545-1549
Published online on: 01 September 2003

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Rad52 gene mutations in breast/ovarian cancer families and sporadic ovarian carcinoma patients

Dan Tong, Tanja Volm, Elke Eberhardt, Michael Krainer, Sepp Leodolter, Rolf Kreienberg, Robert Zeillinger
Pages: 1551-1553
Published online on: 01 September 2003

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The α1-adrenoceptor antagonist terazosin induces prostate cancer cell death through a p53 and Rb independent pathway

Kexin Xu, Xianghong Wang, Patrick M.T. Ling, S. W. Tsao, Y. C. Wong
Pages: 1555-1560
Published online on: 01 September 2003

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Molecular patterns of nuclear and mitochondrial microsatellite alterations in breast tumors

Hafid Alazzouzi, Mireya Farriol, Eloi Espín, Manel Armengol, Manel Pena, Karin Zeh, Simó Schwartz
Pages: 1561-1567
Published online on: 01 September 2003

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Establishment and characterization of sublines of LNCaP human prostate cancer cells

X. Steven Wan, Zhaozong Zhou, Vernon Steele, Levy Kopelovich, Ann R. Kennedy
Pages: 1569-1575
Published online on: 01 September 2003

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Biochemical characterization of soluble Tn glycoproteins from malignant effusions of patients with carcinomas

Teresa Freire, Andrea Medeiros, Celso A. Reis, Francisco X. Real, Eduardo Osinaga
Pages: 1577-1585
Published online on: 01 September 2003

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Evaluation of anti-tumour effects of oral fenretinide (4-HPR) in rats with human neuroblastoma xenografts

Frida Ponthan, Magnus Lindskog, Nina Karnehed, Juan Castro, Per Kogner
Pages: 1587-1592
Published online on: 01 September 2003

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Induction chemotherapy for bone sarcoma in adults: Correlation of results with erbB-4 expression

Ofer Merimsky, Yehuda Kollender, Josephine Issakov, Moshe Inbar, Gideon Flusser, Dafna Benayahu, Isaac Meller, Jacob Bickels
Pages: 1593-1599
Published online on: 01 September 2003

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Gleditsia sinensis fruit extract is a potential chemotherapeutic agent in chronic and acute myelogenous leukemia

Larry Ming Cheung Chow, Chung Hin Chui, Johnny Cheuk On Tang, Ivy Tuang Ngo Teo, Fung Yi Lau, Gregory Yin Ming Cheng, Raymond Siu Ming Wong, Thomas Wai Tong Leung, Ka Bik Lai, Mabel Yin Chun Yau, Dean Gou, Albert Sun Chi Chan
Pages: 1601-1607
Published online on: 01 September 2003

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Variable cytotoxicity of amifostine in malignant and non-malignant cell lines

Baruch Brenner, Lina Wasserman, Einat Beery, Jardena Nordenberg, Jacob Schechter, Haim Gutman, Eyal Fenig
Pages: 1609-1613
Published online on: 01 September 2003

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Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population (Review)

Deyin Xing, Wen Tan, Dongxin Lin
Pages: 1615-1623
Published online on: 01 September 2003

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Angiogenesis and the immune response as targets for the prevention and treatment of colorectal cancer (Review)

Ricky A. Sharma, Angus G. Dalgleish, William P. Steward, Kenneth J. O'Byrne
Pages: 1625-1631
Published online on: 01 September 2003

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The Chinese medicinal herbal formula ZYD88 inhibits cell growth and promotes cell apoptosis in prostatic tumor cells

Yuan-Shan Zhu, Ying Huang, Li-Qun Cai, Jeff Zhu, Quwen Duan, Yanwen Duan, Julianne Imperato-McGinley
Pages: 1633-1639
Published online on: 01 September 2003

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Evaluation of immunohistochemical parameters as prognostic markers in malignant fibrous histiocytoma

Jan Åhlén, Wendy W.-H. Weng, Otte Brosjö, Anette Von Rosen, Olle Larsson, Catharina Larsson
Pages: 1641-1645
Published online on: 01 September 2003

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GM-CSF secreted by murine adenocarcinoma cells modulates tumor progression and immune activity

M. J. Diament, M. I. Stillitani, L. Puricelli, E. Bal de Kier-Joffe, S. Klein
Pages: 1647-1652
Published online on: 01 September 2003

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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