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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2005 Volume 16 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Blockage of the ERK signaling pathway abrogates the SCAP ligand-induced transcriptional activation of the LDL receptor gene in HepG2 cells

Parveen Abidi, Fang Zhang, Cong Li, Jingwen Liu
Pages: 779-785
Published online on: 01 November 2005

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Article

G protein-coupled APJ receptor signaling induces focal adhesion formation and cell motility

Yasumi Hashimoto, Junji Ishida, Rie Yamamoto, Kae Fujiwara, Sachie Asada, Yoshitoshi Kasuya, Naoki Mochizuki, Akiyoshi Fukamizu
Pages: 787-792
Published online on: 01 November 2005

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Article

The exploration of joint-specific immunoreactions on immunoglobulins G of anti-glucose-6-phosphate isomerase antibody-positive patients with rheumatoid arthritis

Isao Matsumoto, Yoshifumi Muraki, Takanori Yasukochi, Zhang Hua, Yuko Kori, Taichi Hayashi, Daisuke Goto, Satoshi Ito, Akito Tsutsumi, Kotaro Ikeda, Hiroshi Sumichika, Takayuki Sumida
Pages: 793-800
Published online on: 01 November 2005

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Article

Soluble amyloid β-peptide and myelin basic protein strongly stimulate, alone and in synergism with combined proinflammatory cytokines, the expression of functional nitric oxide synthase-2 in normal adult human astrocytes

Anna Chiarini, Ilaria Dal Pra, Lia Menapace, Raffaella Pacchiana, James F. Whitfield, Ubaldo Armato
Pages: 801-807
Published online on: 01 November 2005

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Article

Nuclear localization of a novel protein, RGPR-p117, in cloned normal rat kidney proximal tubular epithelial cells

Natsumi Sawada, Taeko Nakagawa, Tomiyasu Murata, Masayoshi Yamaguchi
Pages: 809-814
Published online on: 01 November 2005

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Article

Detection of HPV 52, 58 and 87 in cervicovaginal intraepithelial lesions of HIV infected women

Susanne Haas, Tjoung-Won Park, Esther Voigt, Reinhard Büttner, Sabine Merkelbach-Bruse
Pages: 815-819
Published online on: 01 November 2005

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Article

Transfecting the multidrug resistance protein 2 gene improves transcellular organic anion transport

Toshio Itani, Yoshinao Kobayashi, Makoto Kuroda, Ning Ma, Rumi Mifuji, Naohito Urawa, Yuji Tanaka, Masahiko Kaito, Yukihiko Adachi
Pages: 821-825
Published online on: 01 November 2005

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Article

A novel single-nucleotide substitution, Glu 4 Lys, in the leukotriene C4 synthase gene associated with allergic diseases

Kaori Yoshikawa, Eiko Matsui, Hideo Kaneko, Toshiyuki Fukao, Ryosuke Inoue, Takahide Teramoto, Shinji Shinoda, Osamu Fukutomi, Minako Aoki, Kimiko Kasahara, Naomi Kondo
Pages: 827-831
Published online on: 01 November 2005

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Article

Induction of heat shock protein 72 in C6 glioma cells by methyl jasmonate through ROS-dependent heat shock factor 1 activation

Su Young Oh, Ji Hye Kim, Min Jung Park, Sun Mi Kim, Chang Shin Yoon, Young Mi Joo, Jang Su Park, Song Iy Han, Hye Gyeong Park, Ho Sung Kang
Pages: 833-839
Published online on: 01 November 2005

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Article

Implication of reactive oxygen species, ERK1/2, and p38MAPK in sodium salicylate-induced heat shock protein 72 expression in C6 glioma cells

Myoung Suk Seo, Su Young Oh, Min Jung Park, Sun Mi Kim, Min Young Kim, Song Iy Han, Hye Gyeong Park, Ho Sung Kang
Pages: 841-849
Published online on: 01 November 2005

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Article

Identification of novel mutations of IRF6 gene in Chinese families with Van der Woude syndrome

Xiao-Qian Ye, Hui-Xi Jin, Li-Song Shi, Ming-Wen Fan, Guang-Tai Song, Hua-Li Fan, Zhuan Bian
Pages: 851-856
Published online on: 01 November 2005

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Article

Quantitative detection of telomerase activity by real-time TRAP assay in the body fluids of cancer patients

Woo Young Shim, Kyu Hyun Park, Hei-Chul Jeung, Yong Tae Kim, Tae Soo Kim, Woo Jin Hyung, Sung Hwan An, Sang Hwa Yang, Sung Hoon Noh, Hyun Cheol Chung, Sun Young Rha
Pages: 857-863
Published online on: 01 November 2005

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Article

Expression of Y-Box binding protein-1 following hypericin-mediated photodynamic therapy in well-differentiated nasopharyngeal cancer in vivo

Hong-Yan Du, Malini Olivo, Ying-Jie Chen, George Yip, Puay-Hoon Tan, Ken Matsumoto, Masafumi Tsujimoto, Boon-Huat Bay
Pages: 865-868
Published online on: 01 November 2005

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Article

Tumor necrosis factor alpha promotes an osteoblast-like phenotype in human aortic valve myofibroblasts: A potential regulatory mechanism of valvular calcification

Jens J. Kaden, Refika Kiliç, Aslihan Sarikoç, Siegfried Hagl, Siegfried Lang, Ursula Hoffmann, Martina Brueckmann, Martin Borggrefe
Pages: 869-872
Published online on: 01 November 2005

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Article

Role of protein kinase C in expression of granulocyte-colony stimulating factor and granulocyte macrophage-colony stimulating factor in lung cancer cells

Yoshiki Uemura, Makoto Kobayashi, Hideshi Nakata, Tetsuya Kubota, Tsuyako Saito, Kentaro Bandobashi, Hirokuni Taguchi
Pages: 873-881
Published online on: 01 November 2005

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Article

Marked telomere fluctuation of leukocytes during graft-versus-host disease in allogeneic stem cell transplantation

Goro Sashida, Junko H. Ohyashiki, Naoshi Kubota, Nahoko Shoji, Yuko Ishii, Tetsuzo Tauchi, Yukihiko Kimura, Jerry W. Shay, Kazuma Ohyashiki
Pages: 883-888
Published online on: 01 November 2005

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Article

Differential-expression and tyrosine-phosphorylation profiles of caveolin isoforms in human T cell leukemia cell lines

Yuichiro Tsuji, Michiyo Hatanaka, Tamaki Maeda, Tsukasa Seya, Hiroshi Takenaka, Akira Shimizu
Pages: 889-893
Published online on: 01 November 2005

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Article

Synthesis and evaluation of trimethoxyphenyl isoxazolidines as inhibitors of secretory phospholipase A2 with anti-inflammatory activity

M. P. Sadashiva, A. Nataraju, H. Mallesha, R. Rajesh, B. S. Vishwanath, K. S. Rangappa
Pages: 895-904
Published online on: 01 November 2005

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Article

LASS6, an additional member of the longevity assurance gene family

Arndt Weinmann, Peter R. Galle, Andreas Teufel
Pages: 905-910
Published online on: 01 November 2005

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Article

Maintenance of open DNA base pairs through histone acetylated lysine-purine interaction leading to transcriptional activation: A proposed mechanism

Solon Georghiou, Anas M. Ababneh
Pages: 911-917
Published online on: 01 November 2005

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Article

Phylogeny of the TMEM16 protein family: Some members are overexpressed in cancer

Blanca E. Galindo, Victor D. Vacquier
Pages: 919-924
Published online on: 01 November 2005

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Article

Inhibition of proteasome activity in Gleditsia sinensis fruit extract-mediated apoptosis on human carcinoma cells

Filly Cheung, Chung Hin Chui, Albert Sun Chi Chan, Fung Yi Lau, Gregory Yin Ming Cheng, Raymond Siu Ming Wong, Stanton Hon Lung Kok, Ivy Tuang Ngo Teo, Chor Hing Cheng, Johnny Cheuk On Tang
Pages: 925-929
Published online on: 01 November 2005

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Article

Antiproliferation and induction of cell death of Phaffia rhodozyma (Xanthophyllomyces dendrorhous) extract fermented by brewer malt waste on breast cancer cells

Ivy Tuang Ngo Teo, Chung Hin Chui, Johnny Cheuk On Tang, Fung Yi Lau, Gregory Yin Ming Cheng, Raymond Siu Ming Wong, Stanton Hon Lung Kok, Chor Hing Cheng, Albert Sun Chi Chan, Kwok Ping Ho
Pages: 931-936
Published online on: 01 November 2005

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Article

Regulation of tyrosine phosphorylation during the CD40-mediated rescue of Ramos-BL B cells from BCR-triggered apoptosis

Kroum K. Hristov, Kirstine A. Knox, Vanio I. Mitev
Pages: 937-941
Published online on: 01 November 2005

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Article

UV-induced NF-κB activation and expression of IL-6 is attenuated by (-)-epigallocatechin-3-gallate in cultured human keratinocytes in vitro

Jiping Xia, Xiuzu Song, Zhigang Bi, Wenming Chu, Yinsheng Wan
Pages: 943-950
Published online on: 01 November 2005

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Article

The order of PNA-FISH-detected chromosomal telomere lengths in human T-cells is rather stable, even under the influence of strong mutagens

U. Wick, E. Gebhart
Pages: 951-957
Published online on: 01 November 2005

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Article

Comparative genomics on FGF16 orthologs

Yuriko Katoh, Masaru Katoh
Pages: 959-963
Published online on: 01 November 2005

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

DUSP26: Unveiling a critical molecular mediator and therapeutic target in developmental dysplasia of the hip‑associated secondary osteoarthritis

Enbo Wang, Haixiang Zhang, Dechao Wu, Sadik Ali, Xianglu Ji
Article Number: 105
Published online on: 26 February 2026

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mTOR signaling pathway in primary Sjögren's syndrome: Pathogenesis and potential therapeutic targets (Review)

Rongxiu Huo, Yanting Yang, Chengcheng Wei, Yang Yang, Danli Meng, Jinying Lin, Xinxiang Huang
Article Number: 104
Published online on: 25 February 2026

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Article Open Access

Bumetanide‑blocked SLC12A2 exerts a protective effect in experimental diabetic retinopathy

Yuting Zhang, Xiuli Wang, Qinyue Xie, Yue Huang, Dongjia Huang, Ziqing Liu, Tong Xu, Man Ni, Hongwei Yang
Article Number: 103
Published online on: 25 February 2026

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Article Open Access

Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 102
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] A novel role for Livin in the response to ultraviolet B radiation and pterygium development

Shuang-Qing Wu, Qi-Bin Xu, Wen-Yan Sheng, Lin-Ya Su, Li-Wei Zhu
Article Number: 101
Published online on: 24 February 2026

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Article Open Access

Endothelial UNC5B regulates blood‑retinal barrier homeostasis

Yujia Yao, Suyu Wang, Jiajun Li, Qianzi Jin, Ziyi Chen, Qin Jiang, Keran Li
Article Number: 100
Published online on: 20 February 2026

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Metabolic hubs in reproduction: The regulatory network of lipid droplets in gamete and embryo physiology (Review)

Liuzhu Pan, Zongzhuang Wen, Yi Jin
Article Number: 99
Published online on: 17 February 2026

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The role and mechanism of IL‑35 in myasthenia gravis (Review)

Jing Mao, Lin-Ming Zhang, Yan-Lin Zhu, Shu-Ji Gao, Ming-Wei Liu
Article Number: 98
Published online on: 17 February 2026

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Article Open Access

miRNA‑378a‑5p attenuates the development of abdominal aortic aneurysm via ABLIM1‑MKL1 signaling pathways

Jing Wang, Yujia Zou, Yani Wang, Zheming Yang, Daoshen Liu, Xiaolin Su, Haixu Song, Kai Xu, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 97
Published online on: 16 February 2026

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Dysregulated post‑translational modifications in granulosa cells drive ovarian dysfunction and potential infertility applications (Review)

Yufei Zhong, Yunfei Zou, Zhuoyuan Yang, Junjun Wang, Zezheng Pan, Jiugeng Feng
Article Number: 96
Published online on: 16 February 2026

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Microglia‑mediated neuroinflammation in intracerebral hemorrhage: Pathological mechanisms and implications for therapeutic development (Review)

Xuehui Fan, Changzhi Pu, Luyi Zhong, Oucheng Wang, Binyi Zhao, Dongyi Liao, Xue Bai, Guiquan Chen, Guoqiang Yang
Article Number: 95
Published online on: 16 February 2026

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Correction Open Access

[Corrigendum] Silencing of Rac1 modifies lung cancer cell migration, invasion and actin cytoskeleton rearrangements and enhances chemosensitivity to antitumor drugs

Qing-Yong Chen, Li-Qun Xu, De-Min Jiao, Qing-Hua Yao, Yan-Yi Wang, Hui-Zhen Hu, Yu-Quan Wu, Jia Song, Jie Yan, Li-Jun Wu
Article Number: 94
Published online on: 12 February 2026

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Article Open Access

Orcinol glucoside ameliorates pulmonary fibrosis by suppressing hyaluronic acid synthesis and macrophage M2 polarization via targeting hyaluronic acid synthase 2

Caizi Li, Xinglinzi Tang, Xiaoru Luo, Xin Lai, Jing Yang, Zheng Xu, Gulizeba Muhetaer, Yizi Xie, Xiufang Huang, Hang Li
Article Number: 93
Published online on: 10 February 2026

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Review Open Access

Helicobacter pylori and hyperglycemia fuel gastric cancer glycolysis: Mechanisms and targeted intervention (Review)

Youjia Liu, Fang Wang, Ya Deng, Yanxia Hu, Feihong Shu, Jie Yu, Guoyou Gou, Min Wen, Chen Luo, Xianmin Lu, Qian Du, Jingyu Xu, Rui Xie
Article Number: 92
Published online on: 09 February 2026

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Review Open Access

Targeting the gut‑bone axis through exercise: A novel approach to osteoporosis prevention and treatment (Review)

Jingjing Wu, Siqi Zhang, Junjie Wu, Yuhang Luan, Xingchen Yao, Boyan Xu, Yiting Wang, Yingyue Sheng, Yuzheng Xue, Yilin Ren
Article Number: 91
Published online on: 09 February 2026

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Chorus line in oral squamous cell carcinoma: How stromal and immune players orchestrate tumor progression (Review)

Eliano Cascardi, Mario Della Mura, Nicoletta Sgarro, Silvia Minei, Gerardo Cazzato, Eugenio Maiorano, Lorenzo Lo Muzio, Maria Eleonora Bizzoca, Fábio França Vieira E Silva, Eleonora Lo Muzio, Mario Dioguardi, Andrea Ballini
Article Number: 90
Published online on: 09 February 2026

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Correction Open Access

[Corrigendum] Hsa_circularRNA_0079201 suppresses chondrocyte proliferation and endochondral ossification by regulating the microRNA‑140‑3p/SMAD2 signaling pathway in idiopathic short stature 

Xijuan Liu, Chen Yan, Xueqiang Deng, Jingyu Jia
Article Number: 89
Published online on: 09 February 2026

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Post‑translational modifications in diabetic kidney disease (Review)

Mengfei He, Zihang Wang, Zhuang Miao, Yu Zhao, Lingling Wei, Lijie Zhang, Ruili Yin, Yan Wang, Longyan Yang
Article Number: 88
Published online on: 09 February 2026

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Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)

Hang Ruan, Xiao-Yan Shen, Shi-Yan Liu, Shu-Sheng Li
Article Number: 87
Published online on: 06 February 2026

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Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)

Changliang Ma, Jingxin Li, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Wencui Li, Zhiqin Deng, Zhe Zhao
Article Number: 86
Published online on: 05 February 2026

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Article Open Access

Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling

Qin Deng, Zhongzhong Liu, Qifa Ye, Jia Liu, Zhihui Fu, Xingjian Zhang, Jun Luo, Zhongshan Lu, Pengpeng Yue, Jiansheng Xiao, Qi Xiao
Article Number: 85
Published online on: 05 February 2026

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Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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Correction Open Access

[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Article Open Access

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Review Open Access

Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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May-2026 Volume 57 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

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