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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2019 Volume 54 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4

Yu‑Yu Liu, Chizu Tanikawa, Koji Ueda, Koichi Matsuda
Pages: 1907-1920
Published online on: 15 April 2019

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Article Open Access

miR‑9 depletion suppresses the proliferation of osteosarcoma cells by targeting p16

Song Gao, Jianchao Wang, Shujian Tian, Jianping Luo
Pages: 1921-1932
Published online on: 12 April 2019

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Article Open Access

Icariin enhances the chemosensitivity of cisplatin‑resistant ovarian cancer cells by suppressing autophagy via activation of the AKT/mTOR/ATG5 pathway

Shaoyan Jiang, Hong Chang, Shaojie Deng, Danyi Fan
Pages: 1933-1942
Published online on: 15 April 2019

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Article Open Access

Immunoglobulin‑like transcript 4 and human leukocyte antigen‑G interaction promotes the progression of human colorectal cancer

Zhaoyang Cai, Lu Wang, Yali Han, Wenwen Gao, Xiaojuan Wei, Rumei Gong, Mingliang Zhu, Yuping Sun, Shuwen Yu
Pages: 1943-1954
Published online on: 22 March 2019

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Article Open Access

The targeting of MTDH by miR‑145‑5p or miR‑145‑3p is associated with prognosis and regulates the growth and metastasis of prostate cancer cells Corrigendum in /10.3892/ijo.2023.5477

Dong Pan, Zhaohui Jia, Wensheng Li, Zhongling Dou
Pages: 1955-1968
Published online on: 12 April 2019

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Article Open Access

Salidroside suppresses the growth and invasion of human osteosarcoma cell lines MG63 and U2OS in vitro by inhibiting the JAK2/STAT3 signaling pathway

Lintuo Huang, Zhengxiang Huang, Wenjun Lin, Lu Wang, Xiongbai Zhu, Xin Chen, Shengwu Yang, Chen Lv
Pages: 1969-1980
Published online on: 10 April 2019

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Article Open Access

Overexpressing miR‑335 inhibits DU145 cell proliferation by targeting early growth response 3 in prostate cancer

Peng Zhang, Xiaojie Yang, Li Wang, Dong Zhang, Qidong Luo, Binxian Wang
Pages: 1981-1994
Published online on: 09 April 2019

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Article Open Access

Harmine induces anticancer activity in breast cancer cells via targeting TAZ

Yu Ding, Jinrong He, Juan Huang, Tong Yu, Xiaoyan Shi, Tianzhu Zhang, Ge Yan, Shanshan Chen, Caixia Peng
Pages: 1995-2004
Published online on: 09 April 2019

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Article Open Access

TGF-β-induced long non-coding RNA MIR155HG promotes the progression and EMT of laryngeal squamous cell carcinoma by regulating the miR-155-5p/SOX10 axis

Weina Cui, Wenxia Meng, Lei Zhao, Huan Cao, Weiwei Chi, Baoshan Wang
Pages: 2005-2018
Published online on: 12 April 2019

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Article Open Access

MAT2B promotes proliferation and inhibits apoptosis in osteosarcoma by targeting epidermal growth factor receptor and proliferating cell nuclear antigen

Yuan Yuan, Yonggang Wang, Zimei Liu, Yong Sun, Yang Yao, Wenxi Yu, Zan Shen
Pages: 2019-2029
Published online on: 27 March 2019

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Article Open Access

Phospho‑STAT1 expression as a potential biomarker for anti‑PD‑1/anti‑PD‑L1 immunotherapy for breast cancer

Yuko Nakayama, Kosaku Mimura, Tomoaki Tamaki, Kensuke Shiraishi, Ley‑Fang Kua, Vivien Koh, Masato Ohmori, Ayako Kimura, Shingo Inoue, Hirokazu Okayama, Yoshiyuki Suzuki, Tadao Nakazawa, Daisuke Ichikawa, Koji Kono
Pages: 2030-2038
Published online on: 10 April 2019

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Article Open Access

Myristoylated alanine-rich C-kinase substrate effector domain phosphorylation regulates the growth and radiation sensitization of glioblastoma

Nicholas J. Eustace, Joshua C. Anderson, Catherine P. Langford, Hoa Q. Trummell, Patricia H. Hicks, John S. Jarboe, James A. Mobley, Anita B. Hjelmeland, James R. Hackney, Rune T. Pedersen, Kadia Cosby, G. Yancey Gillespie, James A. Bonner, Christopher D. Willey
Pages: 2039-2053
Published online on: 29 March 2019

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Article Open Access

Simvastatin delays castration‑resistant prostate cancer metastasis and androgen receptor antagonist resistance by regulating the expression of caveolin‑1

Yingying Gao, Luo Li, Ting Li, Lei Ma, Mengjuan Yuan, Wei Sun, Hong Lin Cheng, Lingfang Niu, Zhongbo Du, Zhen Quan, Yanru Fan, Jiaxin Fan, Chunli Luo, Xiaohou Wu
Pages: 2054-2068
Published online on: 05 April 2019

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Article Open Access

Antitumor activity of ginsenoside Rg3 in melanoma through downregulation of the ERK and Akt pathways

Lingbin Meng, Rui Ji, Xiaoming Dong, Xiaochun Xu, Ying Xin, Xin Jiang
Pages: 2069-2079
Published online on: 16 April 2019

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Article Open Access

Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells

Shinji Ohkubo, Romina Mancinelli, Selenia Miglietta, Alessandra Cona, Riccardo Angelini, Gianluca Canettieri, Demetrios A. Spandidos, Eugenio Gaudio, Enzo Agostinelli
Pages: 2080-2094
Published online on: 10 April 2019

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Article Open Access

HOXA6 inhibits cell proliferation and induces apoptosis by suppressing the PI3K/Akt signaling pathway in clear cell renal cell carcinoma

Feixiang Wu, Shasha Wu, Hang Tong, Weiyang He, Xin Gou
Pages: 2095-2105
Published online on: 16 April 2019

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Article

Benzyl isothiocyanate suppresses IGF1R, FGFR3 and mTOR expression by upregulation of miR-99a-5p in human bladder cancer cells

Ji-Fan Lin, Te-Fu Tsai, Yi-Chia Lin, Hung-En Chen, Kuang-Yu Chou, Thomas I-Sheng Hwang
Pages: 2106-2116
Published online on: 26 March 2019

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Article

TGF-β1 protects colon tumor cells from apoptosis through XAF1 suppression

Jung Rock Moon, Shin Ju Oh, Chang Kyun Lee, Sung Gil Chi, Hyo Jong Kim
Pages: 2117-2126
Published online on: 09 April 2019

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Article

C‑mannosylation of R‑spondin2 activates Wnt/β‑catenin signaling and migration activity in human tumor cells

Hayato Mizuta, Kenta Kuga, Takehiro Suzuki, Yuki Niwa, Naoshi Dohmae, Siro Simizu
Pages: 2127-2138
Published online on: 01 April 2019

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Article

Droplet digital PCR as a novel system for the detection of microRNA‑34b/c methylation in circulating DNA in malignant pleural mesothelioma

Hiroki Sato, Junichi Soh, Keisuke Aoe, Nobukazu Fujimoto, Shin Tanaka, Kei Namba, Hidejiro Torigoe, Kazuhiko Shien, Hiromasa Yamamoto, Shuta Tomida, Hiroyuki Tao, Kazunori Okabe, Takumi Kishimoto, Shinichi Toyooka
Pages: 2139-2148
Published online on: 01 April 2019

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Article

Potentiation of mitotane action by rosuvastatin: New insights for adrenocortical carcinoma management

Geoffrey Boulate, Larbi Amazit, Annabelle Naman, Atmane Seck, Angelo Paci, Anne Lombes, Eric Pussard, Eric Baudin, Marc Lombes, Ségolène Hescot
Pages: 2149-2156
Published online on: 03 April 2019

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Article

Long non‑coding RNA H19 regulates cell growth and metastasis via the miR‑22‑3p/Snail1 axis in gastric cancer

Li Gan, Lin Lv, Shengtao Liao
Pages: 2157-2168
Published online on: 04 April 2019

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Article

Forkhead‑box A1 regulates tumor cell growth and predicts prognosis in colorectal cancer

Young‑Lan Park, Seung‑Hun Kim, Sun‑Young Park, Min‑Woo Jung, Sang‑Yoon Ha, Jung‑Ho Choi, Dae‑Seong Myung, Sung‑Bum Cho, Wan‑Sik Lee, Hyun‑Soo Kim, Young‑Eun Joo
Pages: 2169-2178
Published online on: 04 April 2019

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Article

Toll‑like receptor 4 plays a tumor‑suppressive role in cutaneous squamous cell carcinoma

Erina Mikami, Mitsuhiro Kudo, Ryuji Ohashi, Kiyoko Kawahara, Yoko Kawamoto, Kiyoshi Teduka, Takenori Fujii, Taeko Kitamura, Shoko Kure, Kousuke Ishino, Takashi Sakatani, Ryuichi Wada, Hidehisa Saeki, Zenya Naito
Pages: 2179-2188
Published online on: 17 April 2019

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Article

Targeted therapy based on p53 reactivation reduces both glioblastoma cell growth and resistance to temozolomide

Iris Maria Forte, Paola Indovina, Carmelina Antonella Iannuzzi, Donatella Cirillo, Domenico Di Marzo, Daniela Barone, Francesca Capone, Francesca Pentimalli, Antonio Giordano
Pages: 2189-2199
Published online on: 16 April 2019

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Article

Inflammatory responses induced by Helicobacter pylori on the carcinogenesis of gastric epithelial GES‑1 cells

Jianjun Wang, Yongliang Yao, Qinghui Zhang, Shasha Li, Lijun Tang
Pages: 2200-2210
Published online on: 09 April 2019

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Article

miR‑802 inhibits the aggressive behaviors of non‑small cell lung cancer cells by directly targeting FGFR1 Retraction in /10.3892/ijo.2022.5389

Jiexia Zhang, Jun Li, Shiyue Li, Chengzhi Zhou, Yinyin Qin, Xiaoxiang Li
Pages: 2211-2221
Published online on: 29 March 2019

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Article

Tumor‑suppressive microRNA‑223 targets WDR62 directly in bladder cancer

Satoshi Sugita, Hirofumi Yoshino, Masaya Yonemori, Kazutaka Miyamoto, Ryosuke Matsushita, Takashi Sakaguchi, Toshihiko Itesako, Shuichi Tatarano, Masayuki Nakagawa, Hideki Enokida
Pages: 2222-2236
Published online on: 22 March 2019

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Article

Evaluation of pro‑ and anti‑tumor effects induced by three colony‑stimulating factors, G‑CSF, GM‑CSF and M‑CSF, in bladder cancer cells: Is G‑CSF a friend of bladder cancer cells?

Shunta Hori, Makito Miyake, Sayuri Onishi, Yosuke Morizawa, Yasushi Nakai, Yoshihiro Tatsumi, Kenta Onishi, Kota Iida, Daisuke Gotoh, Yoshitaka Itami, Nobumichi Tanaka, Kiyohide Fujimoto
Pages: 2237-2249
Published online on: 04 April 2019

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Article

CDC20 associated with cancer metastasis and novel mushroom‑derived CDC20 inhibitors with antimetastatic activity

Shujie Cheng, Victor Castillo, Daniel Sliva
Pages: 2250-2256
Published online on: 18 April 2019

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Correction Open Access

[Corrigendum] LRIG2 promotes the proliferation and cell cycle progression of glioblastoma cells in vitro and in vivo through enhancing PDGFRβ signaling

Qungen Xiao, Minhai Dong, Fangling Cheng, Feng Mao, Weifeng Zong, Kang Wu, Heping Wang, Ruifan Xie, Baofeng Wang, Ting Lei, Dongsheng Guo
Pages: 2257-2257
Published online on: 02 April 2019

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Correction Open Access

[Corrigendum] Overexpression of SENP1 reduces the stemness capacity of osteosarcoma stem cells and increases their sensitivity to HSVtk/GCV

Fengting Liu, Lili Li, Yanxia Li, Xiaofang Ma, Xiyun Bian, Xiaozhi Liu, Guowen Wang, Dianying Zhang
Pages: 2258-2258
Published online on: 18 March 2019

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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