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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-August 2009 Volume 2 Issue 4

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

Arachidonic acid pathway: A molecular target in human testicular cancer (Review)

Masahide Matsuyama, Rikio Yoshimura
Pages: 527-531
Published online on: 01 July 2009

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Article

Does aspirin acetylate multiple cellular proteins? (Review)

Lloyd F. Alfonso, Kalkunte S. Srivenugopal, G. J. Bhat
Pages: 533-537
Published online on: 01 July 2009

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Article

The intracellular domain of the low affinity p75 nerve growth factor receptor is a death effector domain

Hyun H. Park
Pages: 539-541
Published online on: 01 July 2009

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Article

Betulinic acid exhibits stronger cytotoxic activity on the normal melanocyte NHEM-neo cell line than on drug-resistant and drug-sensitive MeWo melanoma cell lines

Pawel Surowiak, Marcin Drag, Verena Materna, Manfred Dietel, Hermann Lage
Pages: 543-548
Published online on: 01 July 2009

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Article

Prognostic value of matrix Gla protein in breast cancer

Keiko Yoshimura, Kengo Takeuchi, Koichi Nagasaki, Soichi Ogishima, Hiroshi Tanaka, Takuji Iwase, Futoshi Akiyama, Yoshikazu Kuroda, Yoshio Miki
Pages: 549-553
Published online on: 01 July 2009

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Article

Reduced expression of the AdipoR1 gene is correlated with venous invasion in colorectal cancer

Naoto Yamamoto, Takashi Oshima, Kazue Yoshihara, Tsutomu Sato, Roppei Yamada, Shoichi Fujii, Yasuhiko Nagano, Manabu Shiozawa, Makoto Akaike, Nobuyuki Wada, Yasushi Rino, Chikara Kunisaki, Munetaka Masuda, Katsuaki Tanaka, Toshio Imada
Pages: 555-559
Published online on: 01 July 2009

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Article

Quantification of PrPC in bovine peripheral tissues: Analysis in wild-type and PrPC-deficient cattle

Shin-Ichi Kobayashi, Yasuhisa Ano, Akikazu Sakudo, Masayoshi Yukawa, Katsuaki Sigiura, Noboru Manabe, Hiroyuki Nakayama, Takashi Onodera
Pages: 561-566
Published online on: 01 July 2009

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Article

Ultraviolet light exposure and skin cancer in the city of Arica, Chile

Miguel Rivas, María C. Araya, Viviava Durán, Elisa Rojas, Juan Cortes, Gloria M. Calaf
Pages: 567-572
Published online on: 01 July 2009

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Article

Anti-tumor effect and influence of Gekko gecko Linnaeus on the immune system of sarcoma 180-bearing mice

Qi You, Shiyu Han, Yuanlong Zhang, Jianhua Zheng
Pages: 573-577
Published online on: 01 July 2009

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Article

Stable reversal of multidrug resistance in colon cancer cells by RNA interference targeting the MDR1 gene

Zhongsheng Xia, Liyong Zhang, Qikui Chen, Crista Royal, Zhong Yu, Zhongmin Liu, Bao-Ling Adam
Pages: 579-584
Published online on: 01 July 2009

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Article

8-Methoxypsoralen, a potent human CYP2A6 inhibitor, inhibits lung adenocarcinoma development induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice

Hijiri Takeuchi, Kousuke Saoo, Yoko Matsuda, Masanao Yokohira, Keiko Yamakawa, Yu Zeng, Toshiya Kuno, Tetsuya Kamataki, Katsumi Imaida
Pages: 585-588
Published online on: 01 July 2009

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Article

BubR1 and AURKB overexpression are associated with a favorable prognosis in gastric cancer

Megumu Enjoji, Satoru Iida, Hirofumi Sugita, Toshiaki Ishikawa, Hiroyuki Uetake, Mikito Inokuchi, Hiroyuki Yamada, Kazuyuki Kojima, Kenichi Sugihara
Pages: 589-596
Published online on: 01 July 2009

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Article

Sensitivity of liver metabolism in jerboa (Jaculus orientalis) to ciprofibrate, a peroxisome proliferator

Driss Mountassif, Mostafa Kabine, Karima Mounchid, Khadija Mounaji, Norbert Latruffe, M'Hammed Saïd El Kebbaj
Pages: 597-602
Published online on: 01 July 2009

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Article

Prognostic significance of heat shock protein 105 in lung adenocarcinoma

Tomofumi Oda, Eiich Morii, Masayoshi Inoue, Jun-Ichiro Ikeda, Katsuyuki Aozasa, Meinoshin Okumura
Pages: 603-607
Published online on: 01 July 2009

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Article

AKT plays a pivotal role in the acquisition of resistance to 5-fluorouracil in human squamous carcinoma cells

Fukka You, Kenta Aoki, Yatsuji Ito, Shigeru Nakashima
Pages: 609-613
Published online on: 01 July 2009

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Article

Pre-treatment with cyclophosphamide or OX40 (CD134) costimulation targeting regulatory T cell function enhances the anti-tumor immune effect of adoptively transferred CD8+ T cells from wild-type mice

Tomoyuki Ueki, Satoshi Murata, Naomi Kitamura, Eiji Mekata, Tohru Tani
Pages: 615-620
Published online on: 01 July 2009

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Article

Antitumor effects of a cyclooxygenase-2 inhibitor, meloxicam, alone and in combination with radiation and/or 5-fluorouracil in cultured tumor cells

Shiho Ayakawa, Yuta Shibamoto, Chikao Sugie, Masato Ito, Hiroyuki Ogino, Natsuo Tomita, Masaoki Kumagai, Hiromi Murakami, Hiroki Sawa
Pages: 621-625
Published online on: 01 July 2009

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Article

Curcumin induces caspase and calpain-dependent apoptosis in HT29 human colon cancer cells

Nisha Singh, Anuraag Shrivastav, Rajendra K. Sharma
Pages: 627-631
Published online on: 01 July 2009

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Article

Intracellular delivery of 2-deoxy-D-glucose into tumor cells by long-term cultivation and through swelling-activated pathways: implications for radiation treatment

Cholpon S. Djuzenova, Julia Krasnyanska, Martin Kiesel, Lavinia Stingl, Ulrich Zimmermann, Michael Flentje, Vladimir L. Sukhorukov
Pages: 633-640
Published online on: 01 July 2009

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Article

The bone anabolic carotenoids p-hydroxycinnamic acid and β-cryptoxanthin antagonize NF-κB activation in MC3T3 preosteoblasts

Masayoshi Yamaguchi, M. N. Weitzmann
Pages: 641-644
Published online on: 01 July 2009

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Article

Prognostic relevance of the AQP5 −1364C>A polymorphism in primary breast cancer

Sabine Kasimir-Bauer, Martin Heubner, Friedrich Otterbach, Rainer Kimmig, Winfried Siffert, Michael Adamzik
Pages: 645-650
Published online on: 01 July 2009

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Article

Analysis of miR-221 and p27 expression in human gliomas

Xiaoming Lu, Peng Zhao, Chunzhi Zhang, Zhen Fu, Yunxiang Chen, Ailing Lu, Nin Liu, Yongping You, Peiyu Pu, Chunsheng Kang
Pages: 651-656
Published online on: 01 July 2009

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Article

RUNX1T1 is overexpressed in imatinib mesylate-resistant cells

Renata Binato, Andre Mencalha, Luciana Pizzatti, Vanessa Scholl, Ilana Zalcberg, Eliana Abdelhay
Pages: 657-661
Published online on: 01 July 2009

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Article

Pharmacokinetic comparison between pelvic transarterial chemoembolization and transcatheter arterial chemotherapy in an animal model

Tianrong Song, Wei Wang, Ping Liu, Chunlin Chen
Pages: 663-667
Published online on: 01 July 2009

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Article

RNA interference of long-chain acyl-CoA synthetase 6 suppresses the neurite outgrowth of mouse neuroblastoma NB41A3 cells

Hi C. Kim, Sae-Won Lee, Yong-Yeon Cho, Jeong M. Lim, Zae Y. Ryoo, Eun J. Lee
Pages: 669-674
Published online on: 01 July 2009

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Article

Inhibition of telomerase activity in renal cell carcinoma cells by doxorubicin and anti-Fas monoclonal antibody

Xinghua Jin, Yifeli Li, Yongnan Li, Chengluo Jin, Jifei Zhang, Jicheng Liu
Pages: 675-679
Published online on: 01 July 2009

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Journal Cover
August-2026 Volume 34 Issue 2

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Regulatory function of ten‑eleven translocation‑2 in transcriptional mechanisms of demethylated myeloma cells

Lenka Slavickova, Michaela Nemcova, Dominika Svehlova, Veronika Frybortova, Jirina Manakova, Eva Kriegova, Jiri Minarik, Katerina Smesny Trtkova
Article Number: 237
Published online on: 25 June 2026

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Article Open Access

Mulberroside A attenuates H2O2‑induced oxidative stress and barrier dysfunction in Caco‑2 cells through Nrf2/HO‑1‑associated antioxidant signaling

Jianxin Chen, Xiufeng Huang, Xi Chen, Wenhai Jin, Dawei Lin
Article Number: 236
Published online on: 25 June 2026

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Retraction Open Access

[Retracted] Puerarin promotes DUSP1 expression by regulating miR‑133a‑3p in breast cancer

Zhifeng Li, Weiwei Xu, Xiaoyan Ren, Jinhua Xu, Jianxin Chen
Article Number: 235
Published online on: 23 June 2026

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Article Open Access

Sulforaphane attenuates cisplatin‑induced acute kidney injury by inhibiting oxidative stress, inflammation and apoptosis via regulation of NRF2

Zeyu Wu, Mengting Lu, Lei Xu, Ming Luo, Limei Shan, Hongxia Xing, Wenwen Li, Junling Qian
Article Number: 234
Published online on: 19 June 2026

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Article Open Access

Effects of β‑hydroxybutyrate on restoring autophagic flux and mitochondrial function in macrophages exposed to oxidized low‑density lipoprotein

Weiguang Luo, Mei He, Huiling Wang
Article Number: 233
Published online on: 19 June 2026

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Review Open Access

Genetic and molecular mechanisms of hereditary thoracic aortic aneurysm and dissection (Review)

Xiaokang Wang, Qiwen Tan, Jingcheng Xu, Yunlin Yang, Haoyue Huang, Xiaomei Teng, Weihua Wu
Article Number: 232
Published online on: 18 June 2026

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Degraded sulfated galactan derived from Gracilaria fisheri induces immunogenic cell death in MDA‑MB‑231 cells

Tawut Rudtanatip, Yada Polsan, Waraporn Sakaew, Somsuda Somintara, Jenjiralai Phanphak, Jamal El‑Abid, Kanokpan Wongprasert, Choowadee Pariwatthanakun
Article Number: 231
Published online on: 17 June 2026

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Article

Irbesartan ameliorates high‑glucose‑induced epithelial‑mesenchymal transition by downregulating the expression of NLRP3 in HK‑2 cells

Qing Deng, Xiujuan Liu, Dan Wen, Yuhua Cheng, Qing Zhao, Yu Wang, Yu Xiang, Qinkai Chen, Jinlei Lv
Article Number: 230
Published online on: 17 June 2026

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A β‑1,3‑1,6‑glucan from Aureobasidium pullulans enhances apoptotic and autophagic pathways in colorectal cancer cells

Ji-Won Park, Gyeong Mim Mun, Tae Min Jo, Ji A Shin, Takao Kuge, Hisashi Kimoto, Jin-Kyung Kim
Article Number: 229
Published online on: 16 June 2026

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Article Open Access

Growth pattern and molecular biological analysis of primary meningioma cell cultures under different conditions

Stefan Linsler, Anna-Lena Moroldo, Walter Schulz‑Schaeffer, Ralf Ketter, Joachim Oertel, Steffi Urbschat
Article Number: 228
Published online on: 12 June 2026

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Article Open Access

Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

Congcong Xie, Zehao Liu, Tong Chen, Hui Lu, Xiujia Zhang, Wenbo Yu, Jiaxin Zhang, Dandan Shang, Xueying Wang
Article Number: 227
Published online on: 11 June 2026

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Article Open Access

Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

Tao Yang, Hanji Zhang, Mingjun Li, Yiming Ren, Yunbo Sun, Weiyu Hou, Mengqiang Tian
Article Number: 226
Published online on: 11 June 2026

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Retraction Open Access

[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Review Open Access

Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Article Open Access

Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Article Open Access

Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
Published online on: 08 June 2026

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Review Open Access

Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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Correction Open Access

[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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Article Open Access

LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Review Open Access

Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Article Open Access

Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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Retraction Open Access

[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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Review Open Access

SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Review Open Access

Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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Journal Cover
September-2026 Volume 34 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Review Open Access

Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Review Open Access

Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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Retraction Open Access

[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Article Open Access

Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Article Open Access

Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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