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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2008 Volume 22 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Inhibition of experimental abdominal aortic aneurysm in a rat model by the angiotensin receptor blocker valsartan

Yoshikazu Fujiwara, Suguru Shiraya, Takashi Miyake, Satoshi Yamakawa, Motokuni Aoki, Hirofumi Makino, Motonobu Nishimura, Ryuichi Morishita
Pages: 703-708
Published online on: 01 December 2008

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Article Open Access

Thymidylate synthase, dihydropyrimidine dehydrogenase, orotate phosphoribosyltransferase mRNA and protein expression levels in solid tumors in large scale population analysis

Yousuke Fukui, Toshinori Oka, Sekio Nagayama, Peter V. Danenberg, Kathleen D. Danenberg, Masakazu Fukushima
Pages: 709-716
Published online on: 01 December 2008

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Article

Ribozyme-mediated inhibition of caspase-12 activity reduces apoptosis induced by endoplasmic reticulum stress in primary mouse hepatocytes

Shan Jiang, Qing Xie, Huijuan Zhou, Wei Zhang, Xiaqiu Zhou, Guangming Li, Yi Shi, Youxin Jin
Pages: 717-724
Published online on: 01 December 2008

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Article

Lipid peroxides induce early onset of catagen phase in murine hair cycles

Atsushi Naito, Tatsuyuki Midorikawa, Teruhiko Yoshino, Motoyasu Ohdera
Pages: 725-729
Published online on: 01 December 2008

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Article Open Access

Essential nutrients suppress inflammation by modulating key inflammatory gene expression

V. Ivanov, J. Cha, S. Ivanova, T. Kalinovsky, M. W. Roomi, M. Rath, A. Niedzwiecki
Pages: 731-741
Published online on: 01 December 2008

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Article

Maturation-induced down-regulation of MFG-E8 impairs apoptotic cell clearance and enhances endotoxin response

Michael Miksa, Dhruv Amin, Rongqian Wu, Asha Jacob, Mian Zhou, Weifeng Dong, Weng-Lang Yang, Thanjavur S. Ravikumar, Ping Wang
Pages: 743-748
Published online on: 01 December 2008

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Article

Orexin B inhibits proliferation and stimulates specialized function of cultured rat calvarial osteoblast-like cells

Agnieszka Ziolkowska, Marcin Rucinski, Marianna Tyczewska, Ludwik K. Malendowicz
Pages: 749-755
Published online on: 01 December 2008

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Article

Overexpression of MT1-MMP is insufficient to increase experimental liver metastasis of human colon cancer cells

Hirofumi Yamamoto, Shingo Noura, Jiro Okami, Mamoru Uemura, Ichiro Takemasa, Masataka Ikeda, Hideshi Ishii, Mitsugu Sekimoto, Nariaki Matsuura, Morito Monden, Masaki Mori
Pages: 757-761
Published online on: 01 December 2008

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Article

An aqueous extract of green tea Camellia sinensis increases expression of Th1 cell-specific anti-asthmatic markers

Jin-Chul Heo, Jae Rang Rho, Tae-Ho Kim, Shin-Yoon Kim, Sang-Han Lee
Pages: 763-767
Published online on: 01 December 2008

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Article

Characterization of a novel human catechol-O-methyl-transferase mutant with triplet point mutations

Hyoung-Woo Bai, Pan Wang, Bao Ting Zhu
Pages: 769-779
Published online on: 01 December 2008

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Article

LC3-I conversion to LC3-II does not necessarily result in complete autophagy

Pol Giménez-Xavier, Roser Francisco, Francesca Platini, Ricardo Pérez, Santiago Ambrosio
Pages: 781-785
Published online on: 01 December 2008

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Article

Characteristic overexpression of the forkhead box transcription factor Foxf1 in Patched-associated tumors

Danielle S. Wendling, Clemens Lück, Dietrich von Schweinitz, Roland Kappler
Pages: 787-792
Published online on: 01 December 2008

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Article

The specific inhibitory effect of demethoxydehydroaltenusin, a derivative of dehydroaltenusin, on mammalian DNA polymerase α

Isoko Kuriyama, Keishi Fukudome, Shinji Kamisuki, Kouji Kuramochi, Kazunori Tsubaki, Kengo Sakaguchi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina
Pages: 793-799
Published online on: 01 December 2008

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Article Open Access

Impact of insulin resistance on the progression of chronic liver diseases

Kosuke Kaji, Hitoshi Yoshiji, Mitsuteru Kitade, Yasuhide Ikenaka, Ryuichi Noguchi, Junichi Yoshii, Koji Yanase, Tadashi Namisaki, Masaharu Yamazaki, Kei Moriya, Tatsuhiro Tsujimoto, Hideto Kawaratani, Takemi Akahane, Masahito Uemura, Hiroshi Fukui
Pages: 801-808
Published online on: 01 December 2008

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Article

Modulation of TNF-α-induced endothelial cell activation by glucosamine, a naturally occurring amino monosaccharide

Yinghua Ju, Jian Hua, Koji Sakamoto, Hideoki Ogawa, Isao Nagaoka
Pages: 809-815
Published online on: 01 December 2008

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Article

Differential sensitivity of breast cancer and melanoma cells to proteasome inhibitor Velcade

Azmi Yerlikaya, Nuray Erin
Pages: 817-823
Published online on: 01 December 2008

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Article

Expression of PPARγ is reduced by medium supplementation with L-glutamine in human colorectal Caco-2 cells

Cathy Fiatte, Cécile Huin, Philippe Collet, François Plénat, Michel Dauça, Hervé Schohn
Pages: 825-832
Published online on: 01 December 2008

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Article

Transcription of genes of p53-dependent apoptosis in acute leukaemia

Peter Racay, Jozef Hatok, Jan Hudecek, Juraj Chudej, Jana Jurecekova, Dusan Dobrota
Pages: 833-839
Published online on: 01 December 2008

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Article

In vitro cytotoxicity of (-)-EGCG octaacetate on MDAMB-231 and SKHep-1 human carcinoma cells: A pharmacological consideration on prodrug design

Stanton Hon Lung Kok, Raymond Siu Ming Wong, Roberto Gambari, Filly Cheung, Wing Sze Lam, Fung Yi Lau, Gregory Yin Ming Cheng, Chor Hing Cheng, Kim Hung Lam, Sau Hing Chan, Johnny Cheuk On Tang, Chung Hin Chui, Kwok Ping Ho
Pages: 841-845
Published online on: 01 December 2008

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Article

Tanshinone IIA down-regulates the protein expression of ErbB-2 and up-regulates TNF-α in colon cancer cells in vitro and in vivo

Chin-Cheng Su, Yi-Hsiang Lin
Pages: 847-851
Published online on: 01 December 2008

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

DUSP26: Unveiling a critical molecular mediator and therapeutic target in developmental dysplasia of the hip‑associated secondary osteoarthritis

Enbo Wang, Haixiang Zhang, Dechao Wu, Sadik Ali, Xianglu Ji
Article Number: 105
Published online on: 26 February 2026

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Review Open Access

mTOR signaling pathway in primary Sjögren's syndrome: Pathogenesis and potential therapeutic targets (Review)

Rongxiu Huo, Yanting Yang, Chengcheng Wei, Yang Yang, Danli Meng, Jinying Lin, Xinxiang Huang
Article Number: 104
Published online on: 25 February 2026

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Article Open Access

Bumetanide‑blocked SLC12A2 exerts a protective effect in experimental diabetic retinopathy

Yuting Zhang, Xiuli Wang, Qinyue Xie, Yue Huang, Dongjia Huang, Ziqing Liu, Tong Xu, Man Ni, Hongwei Yang
Article Number: 103
Published online on: 25 February 2026

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Article Open Access

Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 102
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] A novel role for Livin in the response to ultraviolet B radiation and pterygium development

Shuang-Qing Wu, Qi-Bin Xu, Wen-Yan Sheng, Lin-Ya Su, Li-Wei Zhu
Article Number: 101
Published online on: 24 February 2026

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Article Open Access

Endothelial UNC5B regulates blood‑retinal barrier homeostasis

Yujia Yao, Suyu Wang, Jiajun Li, Qianzi Jin, Ziyi Chen, Qin Jiang, Keran Li
Article Number: 100
Published online on: 20 February 2026

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Review Open Access

Metabolic hubs in reproduction: The regulatory network of lipid droplets in gamete and embryo physiology (Review)

Liuzhu Pan, Zongzhuang Wen, Yi Jin
Article Number: 99
Published online on: 17 February 2026

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The role and mechanism of IL‑35 in myasthenia gravis (Review)

Jing Mao, Lin-Ming Zhang, Yan-Lin Zhu, Shu-Ji Gao, Ming-Wei Liu
Article Number: 98
Published online on: 17 February 2026

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Article Open Access

miRNA‑378a‑5p attenuates the development of abdominal aortic aneurysm via ABLIM1‑MKL1 signaling pathways

Jing Wang, Yujia Zou, Yani Wang, Zheming Yang, Daoshen Liu, Xiaolin Su, Haixu Song, Kai Xu, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 97
Published online on: 16 February 2026

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Dysregulated post‑translational modifications in granulosa cells drive ovarian dysfunction and potential infertility applications (Review)

Yufei Zhong, Yunfei Zou, Zhuoyuan Yang, Junjun Wang, Zezheng Pan, Jiugeng Feng
Article Number: 96
Published online on: 16 February 2026

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Microglia‑mediated neuroinflammation in intracerebral hemorrhage: Pathological mechanisms and implications for therapeutic development (Review)

Xuehui Fan, Changzhi Pu, Luyi Zhong, Oucheng Wang, Binyi Zhao, Dongyi Liao, Xue Bai, Guiquan Chen, Guoqiang Yang
Article Number: 95
Published online on: 16 February 2026

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Correction Open Access

[Corrigendum] Silencing of Rac1 modifies lung cancer cell migration, invasion and actin cytoskeleton rearrangements and enhances chemosensitivity to antitumor drugs

Qing-Yong Chen, Li-Qun Xu, De-Min Jiao, Qing-Hua Yao, Yan-Yi Wang, Hui-Zhen Hu, Yu-Quan Wu, Jia Song, Jie Yan, Li-Jun Wu
Article Number: 94
Published online on: 12 February 2026

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Article Open Access

Orcinol glucoside ameliorates pulmonary fibrosis by suppressing hyaluronic acid synthesis and macrophage M2 polarization via targeting hyaluronic acid synthase 2

Caizi Li, Xinglinzi Tang, Xiaoru Luo, Xin Lai, Jing Yang, Zheng Xu, Gulizeba Muhetaer, Yizi Xie, Xiufang Huang, Hang Li
Article Number: 93
Published online on: 10 February 2026

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Helicobacter pylori and hyperglycemia fuel gastric cancer glycolysis: Mechanisms and targeted intervention (Review)

Youjia Liu, Fang Wang, Ya Deng, Yanxia Hu, Feihong Shu, Jie Yu, Guoyou Gou, Min Wen, Chen Luo, Xianmin Lu, Qian Du, Jingyu Xu, Rui Xie
Article Number: 92
Published online on: 09 February 2026

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Targeting the gut‑bone axis through exercise: A novel approach to osteoporosis prevention and treatment (Review)

Jingjing Wu, Siqi Zhang, Junjie Wu, Yuhang Luan, Xingchen Yao, Boyan Xu, Yiting Wang, Yingyue Sheng, Yuzheng Xue, Yilin Ren
Article Number: 91
Published online on: 09 February 2026

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Review Open Access

Chorus line in oral squamous cell carcinoma: How stromal and immune players orchestrate tumor progression (Review)

Eliano Cascardi, Mario Della Mura, Nicoletta Sgarro, Silvia Minei, Gerardo Cazzato, Eugenio Maiorano, Lorenzo Lo Muzio, Maria Eleonora Bizzoca, Fábio França Vieira E Silva, Eleonora Lo Muzio, Mario Dioguardi, Andrea Ballini
Article Number: 90
Published online on: 09 February 2026

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Correction Open Access

[Corrigendum] Hsa_circularRNA_0079201 suppresses chondrocyte proliferation and endochondral ossification by regulating the microRNA‑140‑3p/SMAD2 signaling pathway in idiopathic short stature 

Xijuan Liu, Chen Yan, Xueqiang Deng, Jingyu Jia
Article Number: 89
Published online on: 09 February 2026

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Post‑translational modifications in diabetic kidney disease (Review)

Mengfei He, Zihang Wang, Zhuang Miao, Yu Zhao, Lingling Wei, Lijie Zhang, Ruili Yin, Yan Wang, Longyan Yang
Article Number: 88
Published online on: 09 February 2026

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Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)

Hang Ruan, Xiao-Yan Shen, Shi-Yan Liu, Shu-Sheng Li
Article Number: 87
Published online on: 06 February 2026

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Review Open Access

Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)

Changliang Ma, Jingxin Li, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Wencui Li, Zhiqin Deng, Zhe Zhao
Article Number: 86
Published online on: 05 February 2026

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Article Open Access

Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling

Qin Deng, Zhongzhong Liu, Qifa Ye, Jia Liu, Zhihui Fu, Xingjian Zhang, Jun Luo, Zhongshan Lu, Pengpeng Yue, Jiansheng Xiao, Qi Xiao
Article Number: 85
Published online on: 05 February 2026

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Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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Correction Open Access

[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Article Open Access

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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Correction Open Access

[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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Journal Cover
May-2026 Volume 57 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Correction Open Access

[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway

Li-Hua Guo, Yu Cao, Run-Tao Zhuang, Yan Han, Jun Li
Article Number: 106
Published online on: 02 March 2026

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