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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2008 Volume 22 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Inhibition of experimental abdominal aortic aneurysm in a rat model by the angiotensin receptor blocker valsartan

Yoshikazu Fujiwara, Suguru Shiraya, Takashi Miyake, Satoshi Yamakawa, Motokuni Aoki, Hirofumi Makino, Motonobu Nishimura, Ryuichi Morishita
Pages: 703-708
Published online on: 01 December 2008

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Article Open Access

Thymidylate synthase, dihydropyrimidine dehydrogenase, orotate phosphoribosyltransferase mRNA and protein expression levels in solid tumors in large scale population analysis

Yousuke Fukui, Toshinori Oka, Sekio Nagayama, Peter V. Danenberg, Kathleen D. Danenberg, Masakazu Fukushima
Pages: 709-716
Published online on: 01 December 2008

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Article

Ribozyme-mediated inhibition of caspase-12 activity reduces apoptosis induced by endoplasmic reticulum stress in primary mouse hepatocytes

Shan Jiang, Qing Xie, Huijuan Zhou, Wei Zhang, Xiaqiu Zhou, Guangming Li, Yi Shi, Youxin Jin
Pages: 717-724
Published online on: 01 December 2008

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Article

Lipid peroxides induce early onset of catagen phase in murine hair cycles

Atsushi Naito, Tatsuyuki Midorikawa, Teruhiko Yoshino, Motoyasu Ohdera
Pages: 725-729
Published online on: 01 December 2008

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Article Open Access

Essential nutrients suppress inflammation by modulating key inflammatory gene expression

V. Ivanov, J. Cha, S. Ivanova, T. Kalinovsky, M. W. Roomi, M. Rath, A. Niedzwiecki
Pages: 731-741
Published online on: 01 December 2008

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Article

Maturation-induced down-regulation of MFG-E8 impairs apoptotic cell clearance and enhances endotoxin response

Michael Miksa, Dhruv Amin, Rongqian Wu, Asha Jacob, Mian Zhou, Weifeng Dong, Weng-Lang Yang, Thanjavur S. Ravikumar, Ping Wang
Pages: 743-748
Published online on: 01 December 2008

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Article

Orexin B inhibits proliferation and stimulates specialized function of cultured rat calvarial osteoblast-like cells

Agnieszka Ziolkowska, Marcin Rucinski, Marianna Tyczewska, Ludwik K. Malendowicz
Pages: 749-755
Published online on: 01 December 2008

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Article

Overexpression of MT1-MMP is insufficient to increase experimental liver metastasis of human colon cancer cells

Hirofumi Yamamoto, Shingo Noura, Jiro Okami, Mamoru Uemura, Ichiro Takemasa, Masataka Ikeda, Hideshi Ishii, Mitsugu Sekimoto, Nariaki Matsuura, Morito Monden, Masaki Mori
Pages: 757-761
Published online on: 01 December 2008

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Article

An aqueous extract of green tea Camellia sinensis increases expression of Th1 cell-specific anti-asthmatic markers

Jin-Chul Heo, Jae Rang Rho, Tae-Ho Kim, Shin-Yoon Kim, Sang-Han Lee
Pages: 763-767
Published online on: 01 December 2008

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Article

Characterization of a novel human catechol-O-methyl-transferase mutant with triplet point mutations

Hyoung-Woo Bai, Pan Wang, Bao Ting Zhu
Pages: 769-779
Published online on: 01 December 2008

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Article

LC3-I conversion to LC3-II does not necessarily result in complete autophagy

Pol Giménez-Xavier, Roser Francisco, Francesca Platini, Ricardo Pérez, Santiago Ambrosio
Pages: 781-785
Published online on: 01 December 2008

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Article

Characteristic overexpression of the forkhead box transcription factor Foxf1 in Patched-associated tumors

Danielle S. Wendling, Clemens Lück, Dietrich von Schweinitz, Roland Kappler
Pages: 787-792
Published online on: 01 December 2008

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Article

The specific inhibitory effect of demethoxydehydroaltenusin, a derivative of dehydroaltenusin, on mammalian DNA polymerase α

Isoko Kuriyama, Keishi Fukudome, Shinji Kamisuki, Kouji Kuramochi, Kazunori Tsubaki, Kengo Sakaguchi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina
Pages: 793-799
Published online on: 01 December 2008

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Article Open Access

Impact of insulin resistance on the progression of chronic liver diseases

Kosuke Kaji, Hitoshi Yoshiji, Mitsuteru Kitade, Yasuhide Ikenaka, Ryuichi Noguchi, Junichi Yoshii, Koji Yanase, Tadashi Namisaki, Masaharu Yamazaki, Kei Moriya, Tatsuhiro Tsujimoto, Hideto Kawaratani, Takemi Akahane, Masahito Uemura, Hiroshi Fukui
Pages: 801-808
Published online on: 01 December 2008

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Article

Modulation of TNF-α-induced endothelial cell activation by glucosamine, a naturally occurring amino monosaccharide

Yinghua Ju, Jian Hua, Koji Sakamoto, Hideoki Ogawa, Isao Nagaoka
Pages: 809-815
Published online on: 01 December 2008

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Article

Differential sensitivity of breast cancer and melanoma cells to proteasome inhibitor Velcade

Azmi Yerlikaya, Nuray Erin
Pages: 817-823
Published online on: 01 December 2008

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Article

Expression of PPARγ is reduced by medium supplementation with L-glutamine in human colorectal Caco-2 cells

Cathy Fiatte, Cécile Huin, Philippe Collet, François Plénat, Michel Dauça, Hervé Schohn
Pages: 825-832
Published online on: 01 December 2008

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Article

Transcription of genes of p53-dependent apoptosis in acute leukaemia

Peter Racay, Jozef Hatok, Jan Hudecek, Juraj Chudej, Jana Jurecekova, Dusan Dobrota
Pages: 833-839
Published online on: 01 December 2008

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Article

In vitro cytotoxicity of (-)-EGCG octaacetate on MDAMB-231 and SKHep-1 human carcinoma cells: A pharmacological consideration on prodrug design

Stanton Hon Lung Kok, Raymond Siu Ming Wong, Roberto Gambari, Filly Cheung, Wing Sze Lam, Fung Yi Lau, Gregory Yin Ming Cheng, Chor Hing Cheng, Kim Hung Lam, Sau Hing Chan, Johnny Cheuk On Tang, Chung Hin Chui, Kwok Ping Ho
Pages: 841-845
Published online on: 01 December 2008

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Article

Tanshinone IIA down-regulates the protein expression of ErbB-2 and up-regulates TNF-α in colon cancer cells in vitro and in vivo

Chin-Cheng Su, Yi-Hsiang Lin
Pages: 847-851
Published online on: 01 December 2008

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Journal Cover
May-2026 Volume 57 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Macrophage SH3 domain‑containing GRB2‑like protein B1 is required for Rab7‑mediated mitophagy in inflammation during sea water drowning acute lung injury

Hongjuan Ning, Jingyu Deng, Yongheng Gao, Wei Zhang, Jian Chen, Xian Guo, Faguang Jin
Article Number: 138
Published online on: 24 March 2026

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Article Open Access

Deferoxamine mitigates neuronal loss following spinal cord injury via ferroptosis inhibition and Nrf2/HO‑1 pathway activation

Ziqian Ma, Xinwei Zhang, Tao Liu, Yan Zhang, Guanghao Li, Xin Yuan, Benqiang Tang, Hangyi Zhao, Liang Liu, Xueming Chen
Article Number: 137
Published online on: 23 March 2026

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Review Open Access

USP10 deubiquitinase: Physiological function, diseases and therapeutic target (Review)

Linlin Zhang, Huajing Sun, Zifan Wang, Zhimei Wang, Qiang Mu, Yukun Liu
Article Number: 136
Published online on: 23 March 2026

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Article Open Access

Siglec‑15 dysregulation and its therapeutic implications in new‑onset type 1 diabetes 

Heming Guo, Yunwen Tao, Sicheng Li, Ying Gu, Yiting Huang, Chen Fang, Ji Hu
Article Number: 135
Published online on: 20 March 2026

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Article Open Access

ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing

Yan Zhao, Yuankai Zhang, Tian Lei, Shangqing Zhang, Kai Nan, Xin Zhang, Li-Hong Fan
Article Number: 134
Published online on: 19 March 2026

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Review Open Access

Targeting pyroptosis in renal fibrosis: From molecular mechanisms to therapeutic horizons (Review)

Yihuai Tian, Quwu Mushuo, Hui Fan, Hongwei Su, Jianchun Li, Qiong Zhang
Article Number: 133
Published online on: 19 March 2026

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Expression of Concern Open Access

[Expression of Concern] Fasudil, a Rho‑associated protein kinase inhibitor, attenuates retinal ischemia and reperfusion injury in rats

Haishan Song, Dianwen Gao
Article Number: 132
Published online on: 18 March 2026

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Review Open Access

Epigenetic regulation in a high-sugar environment (Review)

Huili Zhou, Xinhe Lv, Yu Liang, Dehai Yu, Wanning Wang
Article Number: 131
Published online on: 17 March 2026

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Review Open Access

The roles and heterogeneity of CD8+ T cells in inflammatory bowel disease: A narrative review of insights from single‑cell transcriptomics (Review)

Rui Zhong, Jing Guo, Wujie Ye, Zhihui Deng, Huangan Wu, Qin Qi, Guona Li, Lu Zhu, Yan Huang, Luyi Wu
Article Number: 130
Published online on: 17 March 2026

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Review Open Access

Mechanism of action and clinical application of autophagy in multiple sclerosis (Review)

Dongmei Wang, Qizhi Fu, Ying Zhao, Guangda Li, Yongjie Bai, Yang Yang, Hongna Song, Mingwei Wang, Hua Fan
Article Number: 129
Published online on: 17 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑dependent diabetes mellitus decreases osteoblastogenesis associated with the inhibition of Wnt signaling through increased expression of Sost and Dkk1 and inhibition of Akt activation

Mamiko Hie, Natsumi Iitsuka, Tomoyo Otsuka, Ikuyo Tsukamoto
Article Number: 128
Published online on: 16 March 2026

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Mechanotransduction and its impact on regenerative medicine in orthopedic rehabilitation (Review)

Baohui Wang, Xueqin Zeng, Huajian Liu, Liang Li, Tao Lei, Yafeng Li, Qing Fang, Yi Cao, Bo Dong
Article Number: 127
Published online on: 13 March 2026

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Article Open Access

4‑Acetylantrocamol LT3 suppresses colorectal cancer growth and metastasis via PI3K/AKT and MAPK pathway modulation

Kuen-Tze Lin, Yu-Chieh Hsieh, Pi-Kai Chang, Chih-Wei Lai, Shih-Yu Lee, I-Chuan Yen
Article Number: 126
Published online on: 13 March 2026

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Roles of ubiquitin‑specific peptidase 22 in cellular fate: From embryonic survival to tissue repair, inflammation and metabolism (Review)

Jia-Nan Xiang, Chen-Yang Zhou, Yu-Di Zhao, Xiao Xu, Sun-Bin Ling
Article Number: 125
Published online on: 12 March 2026

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Review Open Access

m6A in adipose tissue inflammation: A novel regulator of obesity and metabolic diseases (Review)

Xiaoting Yang, Xiaodan Wang, Haojun Tang, Shuangxi Tu, Kai Yin, Xiao Zhu
Article Number: 124
Published online on: 12 March 2026

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Expression of Concern Open Access

[Expression of Concern] Visfatin/PBEF/Nampt induces EMMPRIN and MMP‑9 production in macrophages via the NAMPT‑MAPK (p38, ERK1/2)‑NF‑κB signaling pathway

Yuqi Fan, Shu Meng, Yue Wang, Jiatian Cao, Changqian Wang
Article Number: 123
Published online on: 12 March 2026

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Article Open Access

IL‑37/IL‑1R8 blocks keratinocyte acantholysis via suppressing ADAM17/EGFR

Fengxia Hu, Wenjing Chen, Qian Wang, Xiaoyu Zhang, Fuyang Xiao, Jinying Zhang, Junqin Liang
Article Number: 122
Published online on: 12 March 2026

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Reactive oxygen species in fetal growth restriction mechanisms and therapeutic directions (Review)

Di Cheng, Songbin Yang, Cuilan Wang, Kefeng Fan, Fengchun Gao, Qian Sun
Article Number: 121
Published online on: 12 March 2026

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Research progress on the molecular mechanisms of tanshinone IIA in the treatment of cardiovascular and cerebrovascular diseases (Review)

Wen Pei, Ping Lu, Chenhuan Ding, Ying Li, Yong Li
Article Number: 120
Published online on: 12 March 2026

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Ferritin in ferroptosis: Implications for neurodegenerative diseases (Review)

Wenjing Chen, Heng Tian, Ran Wei, Xiaomei Chen, Yiwen Jia
Article Number: 119
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Ursolic acid protects against cisplatin‑induced ototoxicity by inhibiting oxidative stress and TRPV1‑mediated Ca2+‑signaling  

Yang Di, Tao Xu, Yuan Tian, Tingting Ma, Donghao Qu, Yan Wang, Yuhan Lin, Dongyan Bao, Li Yu, Shuangyue Liu, Aimei Wang
Article Number: 118
Published online on: 09 March 2026

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Article Open Access

HELLS inhibits autophagy‑dependent ferroptosis in nasopharyngeal carcinoma by modulating the Nrf2/HO‑1/GPX4 pathway

Chengxun Jin, Jinqiu Li, Siqi Han, Chaoluomeng Bai, Jingpu Yang, Zonggui Wang
Article Number: 117
Published online on: 09 March 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibitory effect of curcumin on angiogenesis in ectopic endometrium of rats with experimental endometriosis

Ying Zhang, Hong Cao, Yue-Yue Hu, Hua Wang, Chang-Jun Zhang
Article Number: 116
Published online on: 09 March 2026

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Article Open Access

Propofol upregulates MFG‑E8 in BV2 cells to inhibit pyroptosis mediated by the NF‑κB/NLRP3 pathway, thereby ameliorating ischemic‑reperfusion neuronal injury

Shewei Guo, Yingwei Zhen, Guosheng Zhou, Zhihua Zhao
Article Number: 115
Published online on: 05 March 2026

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Article Open Access

Exosomal circ0000549 promotes MNNG‑induced gastric cancer through miR‑15b‑5p/KIF1B

Zhaofeng Liang, Zihan Gao, Yue Zhang, Jiajia Song, Hui Qian, Xuezhong Xu
Article Number: 114
Published online on: 04 March 2026

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Expression of Concern Open Access

[Expression of Concern] Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy  

Fangfang Li, Ning Zhang, Qingqing Wu, Yuan Yuan, Zheng Yang, Mengqiao Zhou, Jinxiu Zhu, Qizhu Tang
Article Number: 113
Published online on: 04 March 2026

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Review Open Access

Treatment of pulmonary fibrosis: From disease mechanisms to future novel therapies (Review)

Sen Lu, Yunfei Liu, Xiaohua Li, Qipeng Yao
Article Number: 112
Published online on: 03 March 2026

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Research progress in single‑cell omics technologies for kidney disease (Review)

Jia Xu, Ziwei Chen, Shengyao Li, Xiaoya Wang, Ming Chen
Article Number: 111
Published online on: 03 March 2026

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Review Open Access

CLDN7: Epithelial gatekeeper from physiology to pathology‑roles in cancer and epithelial‑related diseases (Review)

Xiuping Lai, Yan Yan, Lu Sun, Zili Lei, Yanhong Yang
Article Number: 110
Published online on: 03 March 2026

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Review Open Access

Dynamic regulation and targeted intervention of neutrophils in hepatic ischemia‑reperfusion injury (Review)

Sen Lu, Jiale Tong, Jing Jiang, Qin Zhang, Youjin Huang
Article Number: 109
Published online on: 03 March 2026

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Review Open Access

The dual role of the crosstalk between autophagy and ferroptosis in lung cancer treatment: Advances in mechanisms and therapeutic strategies (Review)

Yingying Zhang, Ruxin Shen
Article Number: 108
Published online on: 02 March 2026

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Review Open Access

Mechanistic insights into inflammatory cytokines in adenomyosis‑induced infertility (Review)

Bojiao Yang, Feng Li, Guimao Cao, Mingtu Nuo, Yaxin Shi, Zilu Wang, Jing Jia, Wei Shi, Zhiyong Liu
Article Number: 107
Published online on: 02 March 2026

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Correction Open Access

[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway

Li-Hua Guo, Yu Cao, Run-Tao Zhuang, Yan Han, Jun Li
Article Number: 106
Published online on: 02 March 2026

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Journal Cover
June-2026 Volume 57 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Crosstalk between autophagy and ferroptosis in liver diseases (Review)

Yanming Wei, Kun Zhou, Yuerui Su, Zhihua Luan, Pengcheng Li, Yinxia Chang, Bo Han, Huifang Li, Yuanbiao Qiao, Jinhong Ren
Article Number: 142
Published online on: 26 March 2026

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Article Open Access

circOMA1 delivered by exosomes regulates DRD2‑mediated prolactinoma resistance

Qing Rao, Dimin Zhu, Zongming Wang, Shaolin Zhang, Xueli Li, Shashikiran Tagilapalli, Nan Wang, Weiyu Hu, Wenli Chen, Yonghong Zhu
Article Number: 141
Published online on: 26 March 2026

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Expression of Concern Open Access

[Expression of Concern] Involvement of Cyr61 in the growth, invasiveness and adhesion of esophageal squamous cell carcinoma cells

Jian-Jun Xie, Li-Yan Xu, Yang-Min Xie, Ze-Peng Du, Cai-Hua Feng, Hui Dong, En-Min Li
Article Number: 140
Published online on: 24 March 2026

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Article Open Access

Novel Hsp90 inhibitor JD‑02 inhibits HSV‑1 infection via the Raf/MEK/ERK signaling pathway

Yexuan Zhu, Xiaohui Wang, Jiaying Lin, Xiao Wang, Kai Zheng, Zhe Ren, Ji Xiao, Yifei Wang
Article Number: 139
Published online on: 24 March 2026

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