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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2010 Volume 25 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Characterization of changes in global gene expression in the brain of neuron-specific enolase/human Tau23 transgenic mice in response to overexpression of Tau protein

Jong-Min Woo , So Jung Park, Ho Il Kang, Byoung Guk Kim, Sun Bo Shim, Seung Wan Jee, Su Hae Lee, Ji Soon Sin, Chang Joon Bae, Mee Kyung Jang, Chunghee Cho, Dae Youn Hwang, Chuel Kyu Kim
Pages: 667-675
Published online on: 01 May 2010

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Article Open Access

Longdan Xiegan Tang has immunomodulatory effects on CD4+CD25+ T cells and attenuates pathological signs in MRL/lpr mice

Tzung-Yan Lee, Hen-Hong Chang
Pages: 677-685
Published online on: 01 May 2010

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Article

A small interfering ABCE1-targeting RNA inhibits the proliferation and invasiveness of small cell lung cancer

Bo Huang, Ying Gao, Dali Tian, Maogen Zheng
Pages: 687-693
Published online on: 01 May 2010

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Article

Interleukin-12-anchored exosomes increase cytotoxicity of T lymphocytes by reversing the JAK/STAT pathway impaired by tumor-derived exosomes

Yao Zhang, Xiao-Hou Wu, Chun-Li Luo, Jia-Mo Zhang, Bai-Cheng He, Gang Chen
Pages: 695-700
Published online on: 01 May 2010

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Article

Characterization of auricular chondrocytes and auricular/articular chondrocyte co-cultures in terms of an application in articular cartilage repair

Maren Kuhne, Thilo John, Karym El-Sayed, Ulrike Marzahn, Annekatrin Aue, Benjamin Kohl, Katharina Stoelzel, Wolfgang Ertel, Dieter Blottner, Andreas Haisch, Gundula Schulze-Tanzil
Pages: 701-708
Published online on: 01 May 2010

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Article

Connexin 26 expression correlates with less aggressive phenotype of intestinal type-gastric carcinomas

XiaoLi Liu, Tomoko Furuya, DongYan Li, JingDa Xu, XiXi Cao, QingQuan Li, JiaWen Xu, ZuDe Xu, Kohsuke Sasaki, XiuPing Liu
Pages: 709-716
Published online on: 01 May 2010

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Article

Analysis of cell cycle arrest and apoptosis induced by RCAS1

Takuya Nishinakagawa, Sho Fujii, Tetsuya Nozaki, Tatsuhiro Maeda, Kazuyuki Machida, Munechika Enjoji, Manabu Nakashima
Pages: 717-722
Published online on: 01 May 2010

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Article

Small Rho GTPase Rac1 determines human epidermal stem cell fate in vitro

Linlin Chai, Chuan Cao, Sheng Bi, Xia Dai, Lu Gan, Rui Guo, Shirong Li
Pages: 723-727
Published online on: 01 May 2010

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Article

Resveratrol prevents the impairment of advanced glycosylation end products (AGE) on macrophage lipid homeostasis by suppressing the receptor for AGE via peroxisome proliferator-activated receptor γ activation

Yihua Zhang, Zhidan Luo, Liqun Ma, Qiang Xu, Qihong Yang, Liangyi Si
Pages: 729-734
Published online on: 01 May 2010

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Article

The impact of RNA standardization and heterogeneous gene expression on the results of cDNA array of human breast carcinoma

Reza Khoshnoud, Qimin He, Maria Sylván, Aida Khoshnoud, Madleen Ivarsson, Tommy Fornander, Jonas Bergh, Jan Frisell, Lars-Erik Rutqvist, Sven Skog
Pages: 735-741
Published online on: 01 May 2010

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Article

Genetic risk for myocardial infarction in Japanese individuals with or without chronic kidney disease

Tetsuo Fujimaki, Kimihiko Kato, Kiyoshi Yokoi, Tetsuro Yoshida, Mitsutoshi Oguri, Sachiro Watanabe, Norifumi Metoki, Hidemi Yoshida, Kei Satoh, Yukitoshi Aoyagi, Yoshinori Nozawa, Yoshiji Yamada
Pages: 743-749
Published online on: 01 May 2010

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Article

Pinus massoniana bark extract selectively induces apoptosis in human hepatoma cells, possibly through caspase-dependent pathways

Hongling Ma, Bing Liu, Dongru Feng, Heng Xie, Ruoda Li, Yixing Yuchi, Hongbin Wang, Jinfa Wang
Pages: 751-759
Published online on: 01 May 2010

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Article

Monoacetylcurcumin strongly regulates inflammatory responses through inhibition of NF-κB activation

Masayuki Nishida, Shin Nishiumi, Yoshiyuki Mizushina, Yoshimi Fujishima, Koji Yamamoto, Atsuhiro Masuda, Shigeto Mizuno, Tsuyoshi Fujita, Yoshinori Morita, Hiromu Kutsumi, Hiromi Yoshida, Takeshi Azuma, Masaru Yoshida
Pages: 761-767
Published online on: 01 May 2010

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Article

Highly efficient gene transfer to solid tumors in vivo by tumor-selective replicating retrovirus vectors

Yin-Che Lu, Yi-Ping Luo, Yu-Wen Wang, Chien-Kuo Tai
Pages: 769-775
Published online on: 01 May 2010

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Article

Analysis of expression and structure of the TSG101 gene in cervical cancer cells

J. Broniarczyk, A. K. Olejnik-Schmidt, M. W. Luczak, M. T. Schmidt, M. Dabrowski, A. Józefiak, W. Kedzia, A. Kwasniewska, A. Gozdzicka-Józefiak
Pages: 777-783
Published online on: 01 May 2010

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Article

Linkage and association study of discoidin domain receptor 1 as a novel susceptibility gene for childhood IgA nephropathy

Won-Ho Hahn, Jin-Soon Suh, Byoung-Soo Cho, Sung-Do Kim
Pages: 785-791
Published online on: 01 May 2010

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Article

Ghrelin and obestatin inhibit enucleation-induced adrenocortical proliferation in the rat

Marcin Rucinski, Marcin Trejter, Agnieszka Ziolkowska, Marianna Tyczewska, Ludwik K. Malendowicz
Pages: 793-800
Published online on: 01 May 2010

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Article

Down-regulation of angiotensin II by shRNA reduces collagen synthesis in hepatic stellate cells

Fu Jun Yu, Pei Hong Dong, Xu Fei Fan, Zhuo Lin, Yong Ping Chen, Ji Li
Pages: 801-806
Published online on: 01 May 2010

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Article

Integrative genomic analyses on IL28RA, the common receptor of interferon-λ1, -λ2 and -λ3

Liming Yang, Yuming Luo, Jifu Wei, Shaoheng He
Pages: 807-812
Published online on: 01 May 2010

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Article

Synergistic effect of vasoactive intestinal peptides on TNF-α-induced IL-6 synthesis in osteoblasts: amplification of p44/p42 MAP kinase activation

Hideo Natsume, Haruhiko Tokuda, Jun Mizutani, Seiji Adachi, Rie Matsushima-Nishiwaki, Chiho Minamitani, Kenji Kato, Osamu Kozawa, Takanobu Otsuka
Pages: 813-817
Published online on: 01 May 2010

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Article Open Access

Endothelial nitric oxide synthase gene polymorphisms and the risk of silent brain infarction

Jihwan Song, Ok Joon Kim, Hyun Sook Kim, Su Jin Bae, Sun Pyo Hong, Doyeun Oh, Nam Keun Kim
Pages: 819-823
Published online on: 01 May 2010

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Journal Cover
October-2026 Volume 58 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of adipocytes and their derived extracellular vesicles in the progression, diagnosis and treatment of liver diseases (Review)

Kangrong Li, Muhammad Zubair, Yongmin Yan, Jiahao Xu
Article Number: 293
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] EBM84 attenuates airway inflammation and mucus hypersecretion in an ovalbumin‑induced murine model of asthma

In Sik Shin, Mee Young Lee, Woo Young Jeon, Na Ra Shin, Chang Seob Seo, Hyekyung Ha
Article Number: 292
Published online on: 20 August 2026

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Review Open Access

Decoding fibroblast activation: Transcriptional networks in hepatic stellate cells and across fibrotic organs (Review)

Denita Charoenthanakitkul, Chaiyaboot Ariyachet
Article Number: 291
Published online on: 20 August 2026

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Inflammatory bowel disease treatment: Mechanisms to clinical translation (Review)

Siqi Tang, Guoyou Gou, Youjia Liu, Fang Wang, Feihong Shu, Ya Deng, Ting Zhang, Jingyu Xu, Rui Xie
Article Number: 290
Published online on: 18 August 2026

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Redox biology in PCOS: Biomarkers, mechanistic networks, and targeted interventions (Review)

Yuena Qiu, Xiaojing Guo, Jie An
Article Number: 289
Published online on: 18 August 2026

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Glucose metabolism in osteoporosis: A potential therapeutic target (Review)

Shengyao Peng, Zhuo Yao, Junzhe Guo, Chi Zhang, Keda Yang, Lin Tao
Article Number: 288
Published online on: 17 August 2026

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Retraction Open Access

[Retracted] Engulfment of platelets delays endothelial cell aging via girdin and its phosphorylation

Yong Lan, Yongjun Li, Dajun Li, Peng Li, Jiyang Wang, Yongpeng Diao, Guodong Ye, Yangfang Li
Article Number: 287
Published online on: 17 August 2026

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Article Open Access

α‑Cyperone targets the PAK1‑JNK/NF‑κB axis to modulate dendritic cells maturation and Th2/Th9 differentiation in an asthma model

Hang Hu, Xing Wang, Linlin Guo, Ziling Zeng, Hongmei Tang, Yun Zhang, Jiayao Duan, Kaijin Wang
Article Number: 286
Published online on: 14 August 2026

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Article Open Access

Early high‑frequency spinal cord stimulation modulates the ROS/p38 MAPK/NF‑κB and CXCL10/CXCR3 pathways to alleviate neuropathic pain and promote spinal cord injury repair

Sitong Su, Tao Liu, Honghui Lei, Yang Yu, Caizhi Ma, Xinglang Wang, Haoyuan Chen, Zebin Huang, Meiling Cheng, Tongtong Qian, Fangyong Wang
Article Number: 285
Published online on: 13 August 2026

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Shared mechanisms of musculoskeletal dysfunction in type 2 diabetes mellitus: Insights into future therapeutic directions (Review)

Zhenhong He, Hanyu Li, Yuhan Luo, Yingying Yu, Siyu Li, Tao Zhang, Dingsu Bao
Article Number: 284
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway

Xinying Zhang, Li Zhang, Zhe Chen, Siwei Li, Bingbing Che, Ningning Wang, Junting Chen, Changqing Xu, Can Wei
Article Number: 283
Published online on: 12 August 2026

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Article Open Access

G protein‑coupled receptor kinase 4 governs early kidney development via STAT3 and Nhe3a

Linh Anna Trúc Vu, Julian Gerhards, Lars D. Maerz, Martin D. Burkhalter, Melanie Philipp
Article Number: 282
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Resistant starch prevents tumorigenesis of dimethylhydrazine‑induced colon tumors via regulation of an ER stress‑mediated mitochondrial apoptosis pathway  

Qiuyu Wang, Peng Wang, Zhigang Xiao
Article Number: 281
Published online on: 10 August 2026

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XBP1 signaling from tumor metabolic stress to myeloid driven immunotherapy resistance (Review)

Ziwei Chen, Jiaqi Wu, Wenxi Liu, Jie Tan, Xiaochun Peng, Yanhua Zhang, Gai Liang
Article Number: 280
Published online on: 05 August 2026

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Decoding miRNA‑146a: Mechanisms of action in cardiovascular diseases and endocrine metabolic disorders (Review)

Xiu Yang, Pengcheng Li, Hao Zhao
Article Number: 279
Published online on: 05 August 2026

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Review Open Access

Contribution of p38 MAPK in liver fibrosis: An overview of mechanisms, signaling pathways, and therapeutic targets (Review)

Xueqin Yang, Huarong Li, Hao Ye, Ting Wu, Fangyun Xu, Chao Hu, Chunlei Yu, Pian Ye
Article Number: 278
Published online on: 05 August 2026

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Correction Open Access

[Corrigendum] Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 277
Published online on: 05 August 2026

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Multi‑omics insights into uveitis: From mechanisms to precision medicine (Review)

Chengzhi Liu, Qiong Wu, Mingzhen Yuan, Mingyue Liu, Xinyu Wang, Jiaqi Shen, Xusheng Cao
Article Number: 276
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Effects of miRNA‑455 on cardiac hypertrophy induced by pressure overload

Chuntao Wu, Shimin Dong, Yongjun Li
Article Number: 275
Published online on: 03 August 2026

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Article Open Access

Energy stress activates AMPK to suppress ferroptosis in neurodegenerative proteinopathies

Yuanyuan Yong, Yuxin Hu, Qian Feng, Xiaogang Zhou, Lu Yu, Dalian Qin, Jianing Mi, Jianming Wu, Jianxin Liu, Anguo Wu
Article Number: 274
Published online on: 31 July 2026

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Article Open Access

Brazilin attenuates methylglyoxal‑induced endothelial injury by enhancing eIF5A hypusination and inhibiting the AMPK/mTOR‑mediated autophagy/apoptosis axis in vitro and in vivo

Yu Liang, Jinxiang Chen, Haiyang Li, Junjing Xiong, Jingcan You, Liqun Wang, Jianbo Wu, Youkun Zheng, Mao Luo
Article Number: 273
Published online on: 30 July 2026

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Review Open Access

Post‑translational modifications in atherosclerosis: Roles, mechanisms and therapeutic potential (Review)

Xiaoxiang Xu, Fei Ma, Wei Yu
Article Number: 272
Published online on: 30 July 2026

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Review Open Access

Role of extracellular matrix in liver fibrosis regression and regeneration (Review)

Yuanzhi Zhou, Zeyuan Qiang, Yang Duan, Jiwei Huang, Haichuan Wang
Article Number: 271
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Circulating microRNA profiles and the identification of miR‑593 and miR‑511 which directly target the PROP1 gene in children with combined pituitary hormone deficiency

Yanyan Hu, Qian Wang, Zengmin Wang, Fengxue Wang, Xiaobo Guo, Guimei Li
Article Number: 270
Published online on: 29 July 2026

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Review Open Access

Unveiling the role of spatial transcriptomics in the analysis of the tumor immune microenvironment (Review)

Jialin Jiang, Xinyu Tu, Yi Cao, Qun Yan, Buqing Sai, Jian Ma
Article Number: 269
Published online on: 28 July 2026

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Expression of Concern Open Access

[Expression of Concern] Luteolin protects mice from severe acute pancreatitis by exerting HO‑1‑mediated anti‑inflammatory and antioxidant effects

Jie Xiong, Kezhou Wang, Chunxiao Yuan, Rong Xing, Jianbo Ni, Guoyong Hu, Fengling Chen, Xingpeng Wang
Article Number: 268
Published online on: 27 July 2026

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Article Open Access

circRNA_013145‑miR‑185‑5p‑RhoA axis: A novel mechanism in the pathophysiology of diabetes‑induced erectile dysfunction

Wenhan Huang, Xin Lv, Jiahua Qian, Yihao Chen, Yuhe Si, Jingwei Wang, Jianxiong Ma
Article Number: 267
Published online on: 24 July 2026

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Review Open Access

Gut‑liver‑kidney axis: A systems biology framework for understanding and treating chronic kidney disease (Review)

Jinyi Hou, Yaotan Li, Shijia Lin, Qingqing Liu, Huijuan Zheng, Weijing Liu, Yaoxian Wang, Liang Peng, Zhen Wang
Article Number: 266
Published online on: 23 July 2026

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Review Open Access

Effects of cuproptosis and its application in inflammatory bowel disease (Review)

Li Chen, Francis Atim Akanyibah, Jing Guan, Bing Pei, Bo Wang, Fei Mao
Article Number: 265
Published online on: 23 July 2026

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Journal Cover
November-2026 Volume 58 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Research progress on BTG2 in non‑tumor diseases (Review)

Shuling Li, Xiaomei Liu, Zheng Zhang, Ling Yang, Yuxuan Li, Qiongdan Hu
Article Number: 299
Published online on: 28 August 2026

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Review Open Access

Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review)

Xincheng Feng, Jue Zhang, Qinghong Ma, Chao Sun
Article Number: 298
Published online on: 27 August 2026

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Correction Open Access

[Corrigendum] Tumor‑targeting novel manganese complex induces ROS‑mediated apoptotic and autophagic cancer cell death

Jia Liu, Wenjie Guo, Jing Li, Xiang Li, Ji Geng, Qiuyun Chen, Jing Gao
Article Number: 297
Published online on: 26 August 2026

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Review Open Access

Advances in sirtuin research in lung diseases (Review)

Shuangyun Xi, Weijun Chen, Xiuli Li, Yudan Wang, Yong Ke
Article Number: 296
Published online on: 25 August 2026

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Article Open Access

lncRNA TUG1 mediates palmitic acid‑induced neuronal lipotoxic injury via the miR‑449a‑5p/caspase‑3 and Akt/GSK‑3β axes

Ya-Dong Wei, Peng-Quan Chen, Xin Zheng, Le-Qi Wu, Xin-Yi Wang, Xin-Ran Gao, Jin-Fang Ge
Article Number: 295
Published online on: 25 August 2026

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Retraction Open Access

[Retracted] Downregulation of LINC00707 promotes osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells by regulating DKK1 via targeting miR‑103a‑3p

Jun Liu, Minfei Wu, Guang Feng, Rui Li, Yang Wang, Jianhang Jiao
Article Number: 294
Published online on: 24 August 2026

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