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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2010 Volume 25 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Characterization of changes in global gene expression in the brain of neuron-specific enolase/human Tau23 transgenic mice in response to overexpression of Tau protein

Jong-Min Woo , So Jung Park, Ho Il Kang, Byoung Guk Kim, Sun Bo Shim, Seung Wan Jee, Su Hae Lee, Ji Soon Sin, Chang Joon Bae, Mee Kyung Jang, Chunghee Cho, Dae Youn Hwang, Chuel Kyu Kim
Pages: 667-675
Published online on: 01 May 2010

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Article Open Access

Longdan Xiegan Tang has immunomodulatory effects on CD4+CD25+ T cells and attenuates pathological signs in MRL/lpr mice

Tzung-Yan Lee, Hen-Hong Chang
Pages: 677-685
Published online on: 01 May 2010

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Article

A small interfering ABCE1-targeting RNA inhibits the proliferation and invasiveness of small cell lung cancer

Bo Huang, Ying Gao, Dali Tian, Maogen Zheng
Pages: 687-693
Published online on: 01 May 2010

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Article

Interleukin-12-anchored exosomes increase cytotoxicity of T lymphocytes by reversing the JAK/STAT pathway impaired by tumor-derived exosomes

Yao Zhang, Xiao-Hou Wu, Chun-Li Luo, Jia-Mo Zhang, Bai-Cheng He, Gang Chen
Pages: 695-700
Published online on: 01 May 2010

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Article

Characterization of auricular chondrocytes and auricular/articular chondrocyte co-cultures in terms of an application in articular cartilage repair

Maren Kuhne, Thilo John, Karym El-Sayed, Ulrike Marzahn, Annekatrin Aue, Benjamin Kohl, Katharina Stoelzel, Wolfgang Ertel, Dieter Blottner, Andreas Haisch, Gundula Schulze-Tanzil
Pages: 701-708
Published online on: 01 May 2010

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Article

Connexin 26 expression correlates with less aggressive phenotype of intestinal type-gastric carcinomas

XiaoLi Liu, Tomoko Furuya, DongYan Li, JingDa Xu, XiXi Cao, QingQuan Li, JiaWen Xu, ZuDe Xu, Kohsuke Sasaki, XiuPing Liu
Pages: 709-716
Published online on: 01 May 2010

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Article

Analysis of cell cycle arrest and apoptosis induced by RCAS1

Takuya Nishinakagawa, Sho Fujii, Tetsuya Nozaki, Tatsuhiro Maeda, Kazuyuki Machida, Munechika Enjoji, Manabu Nakashima
Pages: 717-722
Published online on: 01 May 2010

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Article

Small Rho GTPase Rac1 determines human epidermal stem cell fate in vitro

Linlin Chai, Chuan Cao, Sheng Bi, Xia Dai, Lu Gan, Rui Guo, Shirong Li
Pages: 723-727
Published online on: 01 May 2010

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Article

Resveratrol prevents the impairment of advanced glycosylation end products (AGE) on macrophage lipid homeostasis by suppressing the receptor for AGE via peroxisome proliferator-activated receptor γ activation

Yihua Zhang, Zhidan Luo, Liqun Ma, Qiang Xu, Qihong Yang, Liangyi Si
Pages: 729-734
Published online on: 01 May 2010

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The impact of RNA standardization and heterogeneous gene expression on the results of cDNA array of human breast carcinoma

Reza Khoshnoud, Qimin He, Maria Sylván, Aida Khoshnoud, Madleen Ivarsson, Tommy Fornander, Jonas Bergh, Jan Frisell, Lars-Erik Rutqvist, Sven Skog
Pages: 735-741
Published online on: 01 May 2010

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Article

Genetic risk for myocardial infarction in Japanese individuals with or without chronic kidney disease

Tetsuo Fujimaki, Kimihiko Kato, Kiyoshi Yokoi, Tetsuro Yoshida, Mitsutoshi Oguri, Sachiro Watanabe, Norifumi Metoki, Hidemi Yoshida, Kei Satoh, Yukitoshi Aoyagi, Yoshinori Nozawa, Yoshiji Yamada
Pages: 743-749
Published online on: 01 May 2010

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Article

Pinus massoniana bark extract selectively induces apoptosis in human hepatoma cells, possibly through caspase-dependent pathways

Hongling Ma, Bing Liu, Dongru Feng, Heng Xie, Ruoda Li, Yixing Yuchi, Hongbin Wang, Jinfa Wang
Pages: 751-759
Published online on: 01 May 2010

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Article

Monoacetylcurcumin strongly regulates inflammatory responses through inhibition of NF-κB activation

Masayuki Nishida, Shin Nishiumi, Yoshiyuki Mizushina, Yoshimi Fujishima, Koji Yamamoto, Atsuhiro Masuda, Shigeto Mizuno, Tsuyoshi Fujita, Yoshinori Morita, Hiromu Kutsumi, Hiromi Yoshida, Takeshi Azuma, Masaru Yoshida
Pages: 761-767
Published online on: 01 May 2010

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Article

Highly efficient gene transfer to solid tumors in vivo by tumor-selective replicating retrovirus vectors

Yin-Che Lu, Yi-Ping Luo, Yu-Wen Wang, Chien-Kuo Tai
Pages: 769-775
Published online on: 01 May 2010

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Article

Analysis of expression and structure of the TSG101 gene in cervical cancer cells

J. Broniarczyk, A. K. Olejnik-Schmidt, M. W. Luczak, M. T. Schmidt, M. Dabrowski, A. Józefiak, W. Kedzia, A. Kwasniewska, A. Gozdzicka-Józefiak
Pages: 777-783
Published online on: 01 May 2010

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Article

Linkage and association study of discoidin domain receptor 1 as a novel susceptibility gene for childhood IgA nephropathy

Won-Ho Hahn, Jin-Soon Suh, Byoung-Soo Cho, Sung-Do Kim
Pages: 785-791
Published online on: 01 May 2010

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Article

Ghrelin and obestatin inhibit enucleation-induced adrenocortical proliferation in the rat

Marcin Rucinski, Marcin Trejter, Agnieszka Ziolkowska, Marianna Tyczewska, Ludwik K. Malendowicz
Pages: 793-800
Published online on: 01 May 2010

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Article

Down-regulation of angiotensin II by shRNA reduces collagen synthesis in hepatic stellate cells

Fu Jun Yu, Pei Hong Dong, Xu Fei Fan, Zhuo Lin, Yong Ping Chen, Ji Li
Pages: 801-806
Published online on: 01 May 2010

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Article

Integrative genomic analyses on IL28RA, the common receptor of interferon-λ1, -λ2 and -λ3

Liming Yang, Yuming Luo, Jifu Wei, Shaoheng He
Pages: 807-812
Published online on: 01 May 2010

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Synergistic effect of vasoactive intestinal peptides on TNF-α-induced IL-6 synthesis in osteoblasts: amplification of p44/p42 MAP kinase activation

Hideo Natsume, Haruhiko Tokuda, Jun Mizutani, Seiji Adachi, Rie Matsushima-Nishiwaki, Chiho Minamitani, Kenji Kato, Osamu Kozawa, Takanobu Otsuka
Pages: 813-817
Published online on: 01 May 2010

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Article Open Access

Endothelial nitric oxide synthase gene polymorphisms and the risk of silent brain infarction

Jihwan Song, Ok Joon Kim, Hyun Sook Kim, Su Jin Bae, Sun Pyo Hong, Doyeun Oh, Nam Keun Kim
Pages: 819-823
Published online on: 01 May 2010

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Review Open Access

Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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