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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2011 Volume 27 Issue 3

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Evaluation of PMI-5011, an ethanolic extract of Artemisia dracunculus L., on peripheral neuropathy in streptozotocin-diabetic mice

Pierre Watcho, Roman Stavniichuk, Pierre Tane, Hanna Shevalye, Yury Maksimchyk, Pal Pacher, Irina G. Obrosova
Pages: 299-307
Published online on: 11 January 2011

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Article

Inhibin-α subunit expression in uterine endometrioid adenocarcinomas and endometrial cancer cell lines: a potential prognostic factor

Ioannis Mylonas
Pages: 309-318
Published online on: 21 December 2010

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Article

Differential regulation of the biosynthesis of glucose transporters by the PI3-K and MAPK pathways of insulin signaling by treatment with novel compounds from Liriope platyphylla Corrigendum in /10.3892/ijmm.2026.5840

Yoen Kyung Lee, Ji Eun Kim, So Hee Nam, Jun Seo Goo, Sun Il Choi, Young Hwan Choi, Chang Jun Bae, Jong Min Woo, Jung Sik Cho, Dae Youn Hwang
Pages: 319-327
Published online on: 14 December 2010

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Article

Regulation of p38 MAPK phosphorylation inhibits chondrocyte apoptosis in response to heat stress or mechanical stress Retraction in /10.3892/ijmm.2026.5843

Ken Takebe, Takayuki Nishiyama, Shinya Hayashi, Shingo Hashimoto, Takaaki Fujishiro, Noriyuki Kanzaki, Kohei Kawakita, Kenjiro Iwasa, Ryosuke Kuroda, Masahiro Kurosaka
Pages: 329-335
Published online on: 22 December 2010

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Article

Autophagy is required for toll-like receptor-mediated interleukin-8 production in intestinal epithelial cells

Yong-Yu Li, Shunji Ishihara, M. Monowar Aziz, Akihiko Oka, Ryusaku Kusunoki, Yasumasa Tada, Takafumi Yuki, Yuji Amano, Mesbah Uddin Ansary, Yoshikazu Kinoshita
Pages: 337-344
Published online on: 11 January 2011

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Article

Glutathione S-transferase P1 (GSTP1) suppresses cell apoptosis and its regulation by miR-133α in head and neck squamous cell carcinoma (HNSCC)

Muradil Mutallip, Nijiro Nohata, Toyoyuki Hanazawa, Naoko Kikkawa, Shigetoshi Horiguchi, Lisa Fujimura, Kazumori Kawakami, Takeshi Chiyomaru, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
Pages: 345-352
Published online on: 22 December 2010

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Article

Role of tumor necrosis factor-α in the pathogenesis of indomethacin-induced small intestinal injury in mice

Kohei Fukumoto, Yuji Naito, Tomohisa Takagi, Shinya Yamada, Ryusuke Horie, Ken Inoue, Akihito Harusato, Ikuhiro Hirata, Tastushi Omatsu, Katsura Mizushima, Yasuko Hirai, Naohisa Yoshida, Kazuhiko Uchiyama, Takeshi Ishikawa, Osamu  Handa, Hideyuki Konishi, Naoki Wakabayashi, Nobuaki Yagi, Satoshi Kokura, Hiroshi Ichikawa, Masakazu Kita, Toshikazu Yoshikawa
Pages: 353-359
Published online on: 18 January 2011

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Article

Tiny percutaneous needle biopsy: An efficient method for studying cellular and molecular aspects of skeletal muscle in humans

Tiziana Pietrangelo, Luigi D'Amelio, Christian Doria, Rosa Mancinelli, Stefania Fulle, Giorgio Fanò
Pages: 361-367
Published online on: 14 December 2010

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Article

A novel NKX2-5 mutation in familial ventricular septal defect

Juan Wang, Yuan-Feng Xin, Xing-Yuan Liu, Zhong-Min Liu, Xiao-Zhong Wang, Yi-Qing Yang
Pages: 369-375
Published online on: 16 December 2010

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Article

Elevated expression of orexin receptor 2 (HCRTR2) in benign prostatic hyperplasia is accompanied by lowered serum orexin A concentrations

Witold Malendowicz, Marta Szyszka, Agnieszka  Ziolkowska, Marcin Rucinski, Zbigniew Kwias
Pages: 377-383
Published online on: 24 December 2010

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Article

IL-17 expression is correlated with hepatitis B‑related liver diseases and fibrosis

Liyun Wang, Shijun Chen, Keshu Xu
Pages: 385-392
Published online on: 10 January 2011

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Article

microRNA-155 regulates angiotensin II type 1 receptor expression in umbilical vein endothelial cells from severely pre-eclamptic pregnant women

Weiwei Cheng, Te Liu, Feizhou Jiang, Chunmin Liu, Xinrong Zhao, Yongtao Gao, Hui Wang, Zhixue Liu
Pages: 393-399
Published online on: 13 January 2011

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Article

An ethanol extract of Iris nertschinskia induces p53-dependent apoptosis in the MCF7 human breast cancer cell line

Jae-Sik Shin, Seung-Woo Hong, Jin-Gyun Lee, Young-Min Lee, Dae-Won Kim, Jee-Eun Kim, Da-Jung Jung, Sung-Kwan An, Nam-Joo Hong, Daejin Kim, Dong-Hoon Jin, Sok-Young Lee
Pages: 401-405
Published online on: 14 January 2011

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Article

Inhibitory action of Celastrol on hypoxia-mediated angiogenesis and metastasis via the HIF-1α pathway

Lili Huang, Zefu Zhang, Sheng Zhang, Jinghua Ren, Ruiguang Zhang, Hui Zeng, Qingfeng Li, Gang Wu
Pages: 407-415
Published online on: 18 January 2011

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Article

MALDI imaging as a specific diagnostic tool for routine cervical cytology specimens

Kristina Schwamborn, René C. Krieg, Sandra Uhlig, Hans Ikenberg, Axel Wellmann
Pages: 417-421
Published online on: 21 December 2010

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Article

Role of heat shock protein 27 in transforming growth factor-β-stimulated vascular endothelial growth factor release in osteoblasts

Kenji Kato, Haruhiko Tokuda, Seiji Adachi, Rie Matsushima-Nishiwaki, Junichi Yamauchi, Hideo Natsume, Chiho Minamitani, Jun Mizutani, Takanobu Otsuka, Osamu Kozawa
Pages: 423-428
Published online on: 10 January 2011

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Article

Involvement of Cyr61 in the growth, invasiveness and adhesion of esophageal squamous cell carcinoma cells Expression of Concern in /10.3892/ijmm.2026.5811

Jian-Jun Xie, Li-Yan Xu, Yang-Min Xie, Ze-Peng Du, Cai-Hua Feng, Hui Dong, En-Min Li
Pages: 429-434
Published online on: 18 January 2011

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Article

Detection of soluble HFE associated with soluble transferrin receptor in human serum

Kouhei Ohnishi, Yoshihiro Torimoto, Katsuya Ikuta, Hiroki Tanaka, Takaaki Hosoki, Seiji Tanaka, Akiei Hamano, Kazuya Sato, Mikihiro Fujiya, Katsunori Sasaki, Yutaka Kohgo
Pages: 435-439
Published online on: 16 December 2010

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Article

Enhancement of radiation sensitivity in lung cancer cells by celastrol is mediated by inhibition of Hsp90

Ji-Hyun Lee, Kyu Jin Choi, Woo Duck Seo, Soon Young Jang, Mira Kim, Byong  Won Lee, Jun Young Kim, Seongman Kang, Ki Hun Park, Yun-Sil Lee, Sangwoo Bae
Pages: 441-446
Published online on: 18 January 2011

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Article

Early post-operative measurement of cytokine plasma levels combined with pre-operative bilirubin levels identify high-risk patients after liver resection

Christoph W. Strey, Rosa Maria Marquez-Pinilla, Maciej M. Markiewski, Britta Siegmund, Elsie Oppermann, John D. Lambris, Wolf O. Bechstein
Pages: 447-454
Published online on: 28 December 2010

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Article

Porous alginate/poly(ε-caprolactone) scaffolds: preparation, characterization and in vitro biological activity

Claudio Grandi, Rosa Di Liddo, Piergiorgio Paganin, Silvano Lora, Daniele Dalzoppo, Giampietro Feltrin, Chiara Giraudo, Mara Tommasini, Maria Teresa Conconi, Pier Paolo Parnigotto
Pages: 455-467
Published online on: 28 December 2010

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Article

IL23R, NOD2/CARD15, ATG16L1 and PHOX2B polymorphisms in a group of patients with Crohn's disease and correlation with sub-phenotypes

Mattia Lauriola, Giampaolo Ugolini, Stefano Rivetti, Sara Nanì, Giancarlo Rosati, Simone Zanotti, Isacco Montroni, Alessio Manaresi, Davide Zattoni, Andrea Belluzzi, Lucia Castellani, Gabriele D'Uva, Gabriella Mattei, Mario Taffurelli, Pierluigi Strippoli, Rossella Solmi
Pages: 469-477
Published online on: 27 December 2010

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Journal Cover
October-2026 Volume 58 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of adipocytes and their derived extracellular vesicles in the progression, diagnosis and treatment of liver diseases (Review)

Kangrong Li, Muhammad Zubair, Yongmin Yan, Jiahao Xu
Article Number: 293
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] EBM84 attenuates airway inflammation and mucus hypersecretion in an ovalbumin‑induced murine model of asthma

In Sik Shin, Mee Young Lee, Woo Young Jeon, Na Ra Shin, Chang Seob Seo, Hyekyung Ha
Article Number: 292
Published online on: 20 August 2026

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Decoding fibroblast activation: Transcriptional networks in hepatic stellate cells and across fibrotic organs (Review)

Denita Charoenthanakitkul, Chaiyaboot Ariyachet
Article Number: 291
Published online on: 20 August 2026

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Inflammatory bowel disease treatment: Mechanisms to clinical translation (Review)

Siqi Tang, Guoyou Gou, Youjia Liu, Fang Wang, Feihong Shu, Ya Deng, Ting Zhang, Jingyu Xu, Rui Xie
Article Number: 290
Published online on: 18 August 2026

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Redox biology in PCOS: Biomarkers, mechanistic networks, and targeted interventions (Review)

Yuena Qiu, Xiaojing Guo, Jie An
Article Number: 289
Published online on: 18 August 2026

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Glucose metabolism in osteoporosis: A potential therapeutic target (Review)

Shengyao Peng, Zhuo Yao, Junzhe Guo, Chi Zhang, Keda Yang, Lin Tao
Article Number: 288
Published online on: 17 August 2026

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Retraction Open Access

[Retracted] Engulfment of platelets delays endothelial cell aging via girdin and its phosphorylation

Yong Lan, Yongjun Li, Dajun Li, Peng Li, Jiyang Wang, Yongpeng Diao, Guodong Ye, Yangfang Li
Article Number: 287
Published online on: 17 August 2026

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Article Open Access

α‑Cyperone targets the PAK1‑JNK/NF‑κB axis to modulate dendritic cells maturation and Th2/Th9 differentiation in an asthma model

Hang Hu, Xing Wang, Linlin Guo, Ziling Zeng, Hongmei Tang, Yun Zhang, Jiayao Duan, Kaijin Wang
Article Number: 286
Published online on: 14 August 2026

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Article Open Access

Early high‑frequency spinal cord stimulation modulates the ROS/p38 MAPK/NF‑κB and CXCL10/CXCR3 pathways to alleviate neuropathic pain and promote spinal cord injury repair

Sitong Su, Tao Liu, Honghui Lei, Yang Yu, Caizhi Ma, Xinglang Wang, Haoyuan Chen, Zebin Huang, Meiling Cheng, Tongtong Qian, Fangyong Wang
Article Number: 285
Published online on: 13 August 2026

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Shared mechanisms of musculoskeletal dysfunction in type 2 diabetes mellitus: Insights into future therapeutic directions (Review)

Zhenhong He, Hanyu Li, Yuhan Luo, Yingying Yu, Siyu Li, Tao Zhang, Dingsu Bao
Article Number: 284
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway

Xinying Zhang, Li Zhang, Zhe Chen, Siwei Li, Bingbing Che, Ningning Wang, Junting Chen, Changqing Xu, Can Wei
Article Number: 283
Published online on: 12 August 2026

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Article Open Access

G protein‑coupled receptor kinase 4 governs early kidney development via STAT3 and Nhe3a

Linh Anna Trúc Vu, Julian Gerhards, Lars D. Maerz, Martin D. Burkhalter, Melanie Philipp
Article Number: 282
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Resistant starch prevents tumorigenesis of dimethylhydrazine‑induced colon tumors via regulation of an ER stress‑mediated mitochondrial apoptosis pathway  

Qiuyu Wang, Peng Wang, Zhigang Xiao
Article Number: 281
Published online on: 10 August 2026

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XBP1 signaling from tumor metabolic stress to myeloid driven immunotherapy resistance (Review)

Ziwei Chen, Jiaqi Wu, Wenxi Liu, Jie Tan, Xiaochun Peng, Yanhua Zhang, Gai Liang
Article Number: 280
Published online on: 05 August 2026

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Decoding miRNA‑146a: Mechanisms of action in cardiovascular diseases and endocrine metabolic disorders (Review)

Xiu Yang, Pengcheng Li, Hao Zhao
Article Number: 279
Published online on: 05 August 2026

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Review Open Access

Contribution of p38 MAPK in liver fibrosis: An overview of mechanisms, signaling pathways, and therapeutic targets (Review)

Xueqin Yang, Huarong Li, Hao Ye, Ting Wu, Fangyun Xu, Chao Hu, Chunlei Yu, Pian Ye
Article Number: 278
Published online on: 05 August 2026

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Correction Open Access

[Corrigendum] Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 277
Published online on: 05 August 2026

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Review Open Access

Multi‑omics insights into uveitis: From mechanisms to precision medicine (Review)

Chengzhi Liu, Qiong Wu, Mingzhen Yuan, Mingyue Liu, Xinyu Wang, Jiaqi Shen, Xusheng Cao
Article Number: 276
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Effects of miRNA‑455 on cardiac hypertrophy induced by pressure overload

Chuntao Wu, Shimin Dong, Yongjun Li
Article Number: 275
Published online on: 03 August 2026

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Article Open Access

Energy stress activates AMPK to suppress ferroptosis in neurodegenerative proteinopathies

Yuanyuan Yong, Yuxin Hu, Qian Feng, Xiaogang Zhou, Lu Yu, Dalian Qin, Jianing Mi, Jianming Wu, Jianxin Liu, Anguo Wu
Article Number: 274
Published online on: 31 July 2026

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Article Open Access

Brazilin attenuates methylglyoxal‑induced endothelial injury by enhancing eIF5A hypusination and inhibiting the AMPK/mTOR‑mediated autophagy/apoptosis axis in vitro and in vivo

Yu Liang, Jinxiang Chen, Haiyang Li, Junjing Xiong, Jingcan You, Liqun Wang, Jianbo Wu, Youkun Zheng, Mao Luo
Article Number: 273
Published online on: 30 July 2026

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Review Open Access

Post‑translational modifications in atherosclerosis: Roles, mechanisms and therapeutic potential (Review)

Xiaoxiang Xu, Fei Ma, Wei Yu
Article Number: 272
Published online on: 30 July 2026

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Review Open Access

Role of extracellular matrix in liver fibrosis regression and regeneration (Review)

Yuanzhi Zhou, Zeyuan Qiang, Yang Duan, Jiwei Huang, Haichuan Wang
Article Number: 271
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Circulating microRNA profiles and the identification of miR‑593 and miR‑511 which directly target the PROP1 gene in children with combined pituitary hormone deficiency

Yanyan Hu, Qian Wang, Zengmin Wang, Fengxue Wang, Xiaobo Guo, Guimei Li
Article Number: 270
Published online on: 29 July 2026

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Review Open Access

Unveiling the role of spatial transcriptomics in the analysis of the tumor immune microenvironment (Review)

Jialin Jiang, Xinyu Tu, Yi Cao, Qun Yan, Buqing Sai, Jian Ma
Article Number: 269
Published online on: 28 July 2026

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Expression of Concern Open Access

[Expression of Concern] Luteolin protects mice from severe acute pancreatitis by exerting HO‑1‑mediated anti‑inflammatory and antioxidant effects

Jie Xiong, Kezhou Wang, Chunxiao Yuan, Rong Xing, Jianbo Ni, Guoyong Hu, Fengling Chen, Xingpeng Wang
Article Number: 268
Published online on: 27 July 2026

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Article Open Access

circRNA_013145‑miR‑185‑5p‑RhoA axis: A novel mechanism in the pathophysiology of diabetes‑induced erectile dysfunction

Wenhan Huang, Xin Lv, Jiahua Qian, Yihao Chen, Yuhe Si, Jingwei Wang, Jianxiong Ma
Article Number: 267
Published online on: 24 July 2026

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Review Open Access

Gut‑liver‑kidney axis: A systems biology framework for understanding and treating chronic kidney disease (Review)

Jinyi Hou, Yaotan Li, Shijia Lin, Qingqing Liu, Huijuan Zheng, Weijing Liu, Yaoxian Wang, Liang Peng, Zhen Wang
Article Number: 266
Published online on: 23 July 2026

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Review Open Access

Effects of cuproptosis and its application in inflammatory bowel disease (Review)

Li Chen, Francis Atim Akanyibah, Jing Guan, Bing Pei, Bo Wang, Fei Mao
Article Number: 265
Published online on: 23 July 2026

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Journal Cover
November-2026 Volume 58 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Research progress on BTG2 in non‑tumor diseases (Review)

Shuling Li, Xiaomei Liu, Zheng Zhang, Ling Yang, Yuxuan Li, Qiongdan Hu
Article Number: 299
Published online on: 28 August 2026

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Review Open Access

Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review)

Xincheng Feng, Jue Zhang, Qinghong Ma, Chao Sun
Article Number: 298
Published online on: 27 August 2026

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Correction Open Access

[Corrigendum] Tumor‑targeting novel manganese complex induces ROS‑mediated apoptotic and autophagic cancer cell death

Jia Liu, Wenjie Guo, Jing Li, Xiang Li, Ji Geng, Qiuyun Chen, Jing Gao
Article Number: 297
Published online on: 26 August 2026

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Review Open Access

Advances in sirtuin research in lung diseases (Review)

Shuangyun Xi, Weijun Chen, Xiuli Li, Yudan Wang, Yong Ke
Article Number: 296
Published online on: 25 August 2026

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lncRNA TUG1 mediates palmitic acid‑induced neuronal lipotoxic injury via the miR‑449a‑5p/caspase‑3 and Akt/GSK‑3β axes

Ya-Dong Wei, Peng-Quan Chen, Xin Zheng, Le-Qi Wu, Xin-Yi Wang, Xin-Ran Gao, Jin-Fang Ge
Article Number: 295
Published online on: 25 August 2026

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Retraction Open Access

[Retracted] Downregulation of LINC00707 promotes osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells by regulating DKK1 via targeting miR‑103a‑3p

Jun Liu, Minfei Wu, Guang Feng, Rui Li, Yang Wang, Jianhang Jiao
Article Number: 294
Published online on: 24 August 2026

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