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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2012 Volume 29 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Lipid metabolic pathways as lung cancer therapeutic targets: A computational study

Kojiro Yano
Pages: 519-529
Published online on: 30 December 2011

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Article Open Access

IL-33 regulates TNF-α dependent effects in synovial fibroblasts

Elke Kunisch, Saritha Chakilam, Muktheshwar Gandesiri, Raimund W. Kinne
Pages: 530-540
Published online on: 10 January 2012

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Article Open Access

Microregional antitumor activity of a small-molecule hypoxia-inducible factor 1 inhibitor

Kiyoshi Okamoto, Daisuke Ito, Kazuki Miyazaki, Saori Watanabe, Osamu Tohyama, Akira Yokoi, Yoichi Ozawa, Makoto Asano, Takanori Kawamura, Yoshinobu Yamane, Satoshi Nagao, Setsuo Funasaka, Junichi Kamata, Yoshihiko Kotake, Mika Aoki, Naoko Tsukahara, Yoshiharu Mizui, Isao Tanaka, Kohei Sawada
Pages: 541-549
Published online on: 29 December 2011

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Article Open Access

Involvement of AMP-activated protein kinase in TGF-β-stimulated VEGF synthesis in osteoblasts

Jun Mizutani, Haruhiko Tokuda, Rie Matsushima-Nishiwaki, Kenji Kato, Akira Kondo, Hideo Natsume, Osamu Kozawa, Takanobu Otsuka
Pages: 550-556
Published online on: 23 January 2012

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Article Open Access

Resveratrol, a polyphenol phytoalexin, protects cardiomyocytes against anoxia/reoxygenation injury via the TLR4/NF-κB signaling pathway

Cui Zhang, Guosheng Lin, Weiguo Wan, Xuyon Li, Bin Zeng, Bo Yang, Congxin Huang
Pages: 557-563
Published online on: 11 January 2012

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Article

Inhibition airway remodeling and transforming growth factor-β1/Smad signaling pathway by astragalus extract in asthmatic mice Retraction in /10.3892/ijmm.2023.5290

Zheng-Hai Qu, Zhao-Chuan Yang, Lei Chen, Zhi-Dong Lv, Ming-Ji Yi, Ni Ran
Pages: 564-568
Published online on: 23 December 2011

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Article

Fibroblast growth factor 2 inhibits the expression of stromal cell-derived factor 1α in periodontal ligament cells derived from human permanent teeth in vitro

Takeyoshi Asakawa, Naoyuki Chosa, Yoshitaka Yoshimura, Asami Asakawa, Mitsuro Tanaka, Akira Ishisaki, Masato Mitome, Tomokazu Hasegawa
Pages: 569-573
Published online on: 23 December 2011

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Article

Epstein-Barr virus oncoprotein LMP1 mediates survivin upregulation by p53 contributing to G1/S cell cycle progression in nasopharyngeal carcinoma

Lili Guo, Min Tang, Lifang Yang, Lanbo Xiao, Ann M. Bode, Lili Li, Zigang Dong, Ya Cao
Pages: 574-580
Published online on: 17 January 2012

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Article

Hepatitis B virus X protein inhibits extracellular IFN-α-mediated signal transduction by downregulation of type I IFN receptor

Il-Rae Cho, Myungju Oh, Sang Seok Koh, Waraporn Malilas, Ratakorn Srisuttee, Byung Hak Jhun, Sandra Pellegrini, Serge Y. Fuchs, Young-Hwa Chung
Pages: 581-586
Published online on: 03 January 2012

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Article

Nanog and β-catenin: A new convergence point in EpSC proliferation and differentiation

Delong Yin, Linqiang Tian, Yaping Ye, Kunpeng Li, Jiang Wang, Peng Cheng, Anmin Chen, Fengjing Guo, Hui Huang
Pages: 587-592
Published online on: 29 December 2011

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Article

Niacin protects against UVB radiation-induced apoptosis in cultured human skin keratinocytes

Fuquan Lin, Wen Xu, Cuiping Guan, Miaoni Zhou, Weisong Hong, Lifang Fu, Dongyin Liu, Aie Xu
Pages: 593-600
Published online on: 12 January 2012

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Article

miR-200b is involved in intestinal fibrosis of Crohn's disease

Yingwei Chen, Wensong Ge, Leiming Xu, Chunying Qu, Mingjie Zhu, Wenzhu Zhang, Yongtao Xiao
Pages: 601-606
Published online on: 23 January 2012

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Article

Antiproliferative effect of alpinetin in BxPC-3 pancreatic cancer cells Corrigendum in /10.3892/ijmm.2023.5303

Jian Du, Bo Tang, Jingwen Wang, Hongtao Sui, Xueli Jin, Liming Wang, Zhongyu Wang
Pages: 607-612
Published online on: 11 January 2012

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Article

ERK and Akt signaling pathways are involved in advanced glycation end product-induced autophagy in rat vascular smooth muscle cells

Pengfei Hu, Dongwu Lai, Peilin Lu, Jing Gao, Hong He
Pages: 613-618
Published online on: 23 January 2012

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Article

Cilostazol induces cellular senescence and confers resistance to etoposide-induced apoptosis in articular chondrocytes

Kang Mi Kim, Jong Min Kim, Young Hyun Yoo, Jeung Il Kim, Young Chul Park
Pages: 619-624
Published online on: 23 January 2012

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Article

Kanglaite attenuates UVB-induced down-regulation of aquaporin-3 in cultured human skin keratinocytes

Shi-Jun Shan, Ting Xiao, John Chen, Shi-Ling Geng, Chang-Ping Li, Xuegang Xu, Yuxiao Hong, Chao Ji, Ying Guo, Huachen Wei, Wei Liu, Dapeng Li, Hong-Duo Chen
Pages: 625-629
Published online on: 29 December 2011

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Article

The selective mGluR5 agonist CHPG protects against traumatic brain injury in vitro and in vivo via ERK and Akt pathway

Tao Chen, Lei Zhang, Yan Qu, Kai Huo, XiaoFan Jiang, Zhou Fei
Pages: 630-636
Published online on: 28 December 2011

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Article

Altered miRNA expression patterns in Tff2 knock-out mice correlate with cellular pathways of neoplastic development and caloric metabolism

Aftab Ali Shah, Petra Leidinger, Andreas Keller, Anke Wendschlag, Eckart Meese, Nikolaus Blin
Pages: 637-643
Published online on: 10 January 2012

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Article

Novel RS1 mutations associated with X-linked juvenile retinoschisis

Junhui Yi, Shiqiang Li, Xiaoyun Jia, Xueshan Xiao, Panfeng Wang, Xiangming Guo, Qingjiong Zhang
Pages: 644-648
Published online on: 10 January 2012

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Article

Oridonin induces apoptosis and senescence by increasing hydrogen peroxide and glutathione depletion in colorectal cancer cells

Feng-Hou Gao, Feng Liu, Wei Wei, Li-Bin Liu, Mang-Hua Xu, Zhu-Ying Guo, Wei Li, Bin Jiang, Ying-Li Wu
Pages: 649-655
Published online on: 24 January 2012

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Article

Pattern of cancer/testis antigen expression in lung cancer patients

Yeong-Dae Kim, Hae-Rim Park, Myung-Ha Song, Dong-Hoon Shin, Chang-Hun Lee, Min-Ki Lee, Sang-Yull Lee
Pages: 656-662
Published online on: 24 January 2012

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Article

The regulatory role of microRNA-1187 in TNF-α-mediated hepatocyte apoptosis in acute liver failure

Dong Shan Yu, Fang Mei An, Bang Dong Gong, Xiao Gang Xiang, Lan Yi Lin, Hui Wang, Qing Xie
Pages: 663-668
Published online on: 17 January 2012

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Article

Analysis of the coding sequence and expression of the coiled-coil α-helical rod protein 1 gene in normal and neoplastic epithelial cervical cells

Joanna Pacholska-Bogalska, Magdalena Myga-Nowak, Katarzyna Ciepłuch, Agata Józefiak, Anna Kwaśniewska, Anna Goździcka-Józefiak
Pages: 669-676
Published online on: 03 January 2012

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Article

Cloning of the surface layer gene sllB from Bacillus sphaericus ATCC 14577 and its heterologous expression and purification

Yu-Bao Cui, Ying Zhou, Wei-Na Liu, Qing-Wen Chen, Gui-Fang Ma, Wei-Hong Shi, Yun-Gang Wang, Li Yang
Pages: 677-682
Published online on: 19 January 2012

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Article

Females with angina pectoris have altered lipoprotein metabolism with elevated cholesteryl ester transfer protein activity and impaired high-density lipoproteins-associated antioxidant enzymes

Jungho Park, Jae-Ryong Kim, Dong-Gu Shin, Kyung-Hyun Cho
Pages: 683-689
Published online on: 29 December 2011

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Article

Alternative splicing of apoptosis-related genes in imatinib-treated K562 cells identified by exon array analysis

Jing Liu, Yun Xiao, Huo-Mei Xiong, Jing Li, Bo Huang, Hai-Bin Zhang, Dan-Qin Feng, Xi-Min Chen, Xiao-Zhong Wang
Pages: 690-698
Published online on: 29 December 2011

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Article

NOD1 and NOD2 stimulation triggers innate immune responses of human periodontal ligament cells

Do-In Jeon, Se-Ra Park, Mee-Young Ahn, Sang-Gun Ahn, Jong-Hwan Park, Jung-Hoon Yoon
Pages: 699-703
Published online on: 03 January 2012

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Article

Protocadherin-10 is involved in angiogenesis and methylation correlated with multiple myeloma

Ying Li, Ze-song Yang, Jun-jun Song, Qiong Liu, Jian-bin Chen
Pages: 704-710
Published online on: 09 January 2012

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Article

Soybean glyceollins mitigate inducible nitric oxide synthase and cyclooxygenase-2 expression levels via suppression of the NF-κB signaling pathway in RAW 264.7 cells

Eun-Kyung Yoon, Hyun-Kyoung Kim, Song Cui, Yong-Hoon Kim, Sang-Han Lee
Pages: 711-717
Published online on: 12 January 2012

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

DUSP26: Unveiling a critical molecular mediator and therapeutic target in developmental dysplasia of the hip‑associated secondary osteoarthritis

Enbo Wang, Haixiang Zhang, Dechao Wu, Sadik Ali, Xianglu Ji
Article Number: 105
Published online on: 26 February 2026

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Review Open Access

mTOR signaling pathway in primary Sjögren's syndrome: Pathogenesis and potential therapeutic targets (Review)

Rongxiu Huo, Yanting Yang, Chengcheng Wei, Yang Yang, Danli Meng, Jinying Lin, Xinxiang Huang
Article Number: 104
Published online on: 25 February 2026

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Article Open Access

Bumetanide‑blocked SLC12A2 exerts a protective effect in experimental diabetic retinopathy

Yuting Zhang, Xiuli Wang, Qinyue Xie, Yue Huang, Dongjia Huang, Ziqing Liu, Tong Xu, Man Ni, Hongwei Yang
Article Number: 103
Published online on: 25 February 2026

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Article Open Access

Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 102
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] A novel role for Livin in the response to ultraviolet B radiation and pterygium development

Shuang-Qing Wu, Qi-Bin Xu, Wen-Yan Sheng, Lin-Ya Su, Li-Wei Zhu
Article Number: 101
Published online on: 24 February 2026

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Article Open Access

Endothelial UNC5B regulates blood‑retinal barrier homeostasis

Yujia Yao, Suyu Wang, Jiajun Li, Qianzi Jin, Ziyi Chen, Qin Jiang, Keran Li
Article Number: 100
Published online on: 20 February 2026

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Review Open Access

Metabolic hubs in reproduction: The regulatory network of lipid droplets in gamete and embryo physiology (Review)

Liuzhu Pan, Zongzhuang Wen, Yi Jin
Article Number: 99
Published online on: 17 February 2026

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Review Open Access

The role and mechanism of IL‑35 in myasthenia gravis (Review)

Jing Mao, Lin-Ming Zhang, Yan-Lin Zhu, Shu-Ji Gao, Ming-Wei Liu
Article Number: 98
Published online on: 17 February 2026

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Article Open Access

miRNA‑378a‑5p attenuates the development of abdominal aortic aneurysm via ABLIM1‑MKL1 signaling pathways

Jing Wang, Yujia Zou, Yani Wang, Zheming Yang, Daoshen Liu, Xiaolin Su, Haixu Song, Kai Xu, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 97
Published online on: 16 February 2026

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Review Open Access

Dysregulated post‑translational modifications in granulosa cells drive ovarian dysfunction and potential infertility applications (Review)

Yufei Zhong, Yunfei Zou, Zhuoyuan Yang, Junjun Wang, Zezheng Pan, Jiugeng Feng
Article Number: 96
Published online on: 16 February 2026

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Review Open Access

Microglia‑mediated neuroinflammation in intracerebral hemorrhage: Pathological mechanisms and implications for therapeutic development (Review)

Xuehui Fan, Changzhi Pu, Luyi Zhong, Oucheng Wang, Binyi Zhao, Dongyi Liao, Xue Bai, Guiquan Chen, Guoqiang Yang
Article Number: 95
Published online on: 16 February 2026

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Correction Open Access

[Corrigendum] Silencing of Rac1 modifies lung cancer cell migration, invasion and actin cytoskeleton rearrangements and enhances chemosensitivity to antitumor drugs

Qing-Yong Chen, Li-Qun Xu, De-Min Jiao, Qing-Hua Yao, Yan-Yi Wang, Hui-Zhen Hu, Yu-Quan Wu, Jia Song, Jie Yan, Li-Jun Wu
Article Number: 94
Published online on: 12 February 2026

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Article Open Access

Orcinol glucoside ameliorates pulmonary fibrosis by suppressing hyaluronic acid synthesis and macrophage M2 polarization via targeting hyaluronic acid synthase 2

Caizi Li, Xinglinzi Tang, Xiaoru Luo, Xin Lai, Jing Yang, Zheng Xu, Gulizeba Muhetaer, Yizi Xie, Xiufang Huang, Hang Li
Article Number: 93
Published online on: 10 February 2026

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Review Open Access

Helicobacter pylori and hyperglycemia fuel gastric cancer glycolysis: Mechanisms and targeted intervention (Review)

Youjia Liu, Fang Wang, Ya Deng, Yanxia Hu, Feihong Shu, Jie Yu, Guoyou Gou, Min Wen, Chen Luo, Xianmin Lu, Qian Du, Jingyu Xu, Rui Xie
Article Number: 92
Published online on: 09 February 2026

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Review Open Access

Targeting the gut‑bone axis through exercise: A novel approach to osteoporosis prevention and treatment (Review)

Jingjing Wu, Siqi Zhang, Junjie Wu, Yuhang Luan, Xingchen Yao, Boyan Xu, Yiting Wang, Yingyue Sheng, Yuzheng Xue, Yilin Ren
Article Number: 91
Published online on: 09 February 2026

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Review Open Access

Chorus line in oral squamous cell carcinoma: How stromal and immune players orchestrate tumor progression (Review)

Eliano Cascardi, Mario Della Mura, Nicoletta Sgarro, Silvia Minei, Gerardo Cazzato, Eugenio Maiorano, Lorenzo Lo Muzio, Maria Eleonora Bizzoca, Fábio França Vieira E Silva, Eleonora Lo Muzio, Mario Dioguardi, Andrea Ballini
Article Number: 90
Published online on: 09 February 2026

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Correction Open Access

[Corrigendum] Hsa_circularRNA_0079201 suppresses chondrocyte proliferation and endochondral ossification by regulating the microRNA‑140‑3p/SMAD2 signaling pathway in idiopathic short stature 

Xijuan Liu, Chen Yan, Xueqiang Deng, Jingyu Jia
Article Number: 89
Published online on: 09 February 2026

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Review Open Access

Post‑translational modifications in diabetic kidney disease (Review)

Mengfei He, Zihang Wang, Zhuang Miao, Yu Zhao, Lingling Wei, Lijie Zhang, Ruili Yin, Yan Wang, Longyan Yang
Article Number: 88
Published online on: 09 February 2026

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Review Open Access

Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)

Hang Ruan, Xiao-Yan Shen, Shi-Yan Liu, Shu-Sheng Li
Article Number: 87
Published online on: 06 February 2026

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Review Open Access

Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)

Changliang Ma, Jingxin Li, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Wencui Li, Zhiqin Deng, Zhe Zhao
Article Number: 86
Published online on: 05 February 2026

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Article Open Access

Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling

Qin Deng, Zhongzhong Liu, Qifa Ye, Jia Liu, Zhihui Fu, Xingjian Zhang, Jun Luo, Zhongshan Lu, Pengpeng Yue, Jiansheng Xiao, Qi Xiao
Article Number: 85
Published online on: 05 February 2026

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Review Open Access

Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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Correction Open Access

[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Review Open Access

Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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Review Open Access

IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Article Open Access

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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Correction Open Access

[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Review Open Access

Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Review Open Access

Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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Journal Cover
May-2026 Volume 57 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

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