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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2012 Volume 29 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Lipid metabolic pathways as lung cancer therapeutic targets: A computational study

Kojiro Yano
Pages: 519-529
Published online on: 30 December 2011

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Article Open Access

IL-33 regulates TNF-α dependent effects in synovial fibroblasts

Elke Kunisch, Saritha Chakilam, Muktheshwar Gandesiri, Raimund W. Kinne
Pages: 530-540
Published online on: 10 January 2012

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Article Open Access

Microregional antitumor activity of a small-molecule hypoxia-inducible factor 1 inhibitor

Kiyoshi Okamoto, Daisuke Ito, Kazuki Miyazaki, Saori Watanabe, Osamu Tohyama, Akira Yokoi, Yoichi Ozawa, Makoto Asano, Takanori Kawamura, Yoshinobu Yamane, Satoshi Nagao, Setsuo Funasaka, Junichi Kamata, Yoshihiko Kotake, Mika Aoki, Naoko Tsukahara, Yoshiharu Mizui, Isao Tanaka, Kohei Sawada
Pages: 541-549
Published online on: 29 December 2011

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Article Open Access

Involvement of AMP-activated protein kinase in TGF-β-stimulated VEGF synthesis in osteoblasts

Jun Mizutani, Haruhiko Tokuda, Rie Matsushima-Nishiwaki, Kenji Kato, Akira Kondo, Hideo Natsume, Osamu Kozawa, Takanobu Otsuka
Pages: 550-556
Published online on: 23 January 2012

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Article Open Access

Resveratrol, a polyphenol phytoalexin, protects cardiomyocytes against anoxia/reoxygenation injury via the TLR4/NF-κB signaling pathway

Cui Zhang, Guosheng Lin, Weiguo Wan, Xuyon Li, Bin Zeng, Bo Yang, Congxin Huang
Pages: 557-563
Published online on: 11 January 2012

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Article

Inhibition airway remodeling and transforming growth factor-β1/Smad signaling pathway by astragalus extract in asthmatic mice Retraction in /10.3892/ijmm.2023.5290

Zheng-Hai Qu, Zhao-Chuan Yang, Lei Chen, Zhi-Dong Lv, Ming-Ji Yi, Ni Ran
Pages: 564-568
Published online on: 23 December 2011

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Article

Fibroblast growth factor 2 inhibits the expression of stromal cell-derived factor 1α in periodontal ligament cells derived from human permanent teeth in vitro

Takeyoshi Asakawa, Naoyuki Chosa, Yoshitaka Yoshimura, Asami Asakawa, Mitsuro Tanaka, Akira Ishisaki, Masato Mitome, Tomokazu Hasegawa
Pages: 569-573
Published online on: 23 December 2011

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Article

Epstein-Barr virus oncoprotein LMP1 mediates survivin upregulation by p53 contributing to G1/S cell cycle progression in nasopharyngeal carcinoma

Lili Guo, Min Tang, Lifang Yang, Lanbo Xiao, Ann M. Bode, Lili Li, Zigang Dong, Ya Cao
Pages: 574-580
Published online on: 17 January 2012

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Article

Hepatitis B virus X protein inhibits extracellular IFN-α-mediated signal transduction by downregulation of type I IFN receptor

Il-Rae Cho, Myungju Oh, Sang Seok Koh, Waraporn Malilas, Ratakorn Srisuttee, Byung Hak Jhun, Sandra Pellegrini, Serge Y. Fuchs, Young-Hwa Chung
Pages: 581-586
Published online on: 03 January 2012

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Article

Nanog and β-catenin: A new convergence point in EpSC proliferation and differentiation

Delong Yin, Linqiang Tian, Yaping Ye, Kunpeng Li, Jiang Wang, Peng Cheng, Anmin Chen, Fengjing Guo, Hui Huang
Pages: 587-592
Published online on: 29 December 2011

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Article

Niacin protects against UVB radiation-induced apoptosis in cultured human skin keratinocytes

Fuquan Lin, Wen Xu, Cuiping Guan, Miaoni Zhou, Weisong Hong, Lifang Fu, Dongyin Liu, Aie Xu
Pages: 593-600
Published online on: 12 January 2012

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Article

miR-200b is involved in intestinal fibrosis of Crohn's disease

Yingwei Chen, Wensong Ge, Leiming Xu, Chunying Qu, Mingjie Zhu, Wenzhu Zhang, Yongtao Xiao
Pages: 601-606
Published online on: 23 January 2012

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Article

Antiproliferative effect of alpinetin in BxPC-3 pancreatic cancer cells Corrigendum in /10.3892/ijmm.2023.5303

Jian Du, Bo Tang, Jingwen Wang, Hongtao Sui, Xueli Jin, Liming Wang, Zhongyu Wang
Pages: 607-612
Published online on: 11 January 2012

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Article

ERK and Akt signaling pathways are involved in advanced glycation end product-induced autophagy in rat vascular smooth muscle cells

Pengfei Hu, Dongwu Lai, Peilin Lu, Jing Gao, Hong He
Pages: 613-618
Published online on: 23 January 2012

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Article

Cilostazol induces cellular senescence and confers resistance to etoposide-induced apoptosis in articular chondrocytes

Kang Mi Kim, Jong Min Kim, Young Hyun Yoo, Jeung Il Kim, Young Chul Park
Pages: 619-624
Published online on: 23 January 2012

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Article

Kanglaite attenuates UVB-induced down-regulation of aquaporin-3 in cultured human skin keratinocytes

Shi-Jun Shan, Ting Xiao, John Chen, Shi-Ling Geng, Chang-Ping Li, Xuegang Xu, Yuxiao Hong, Chao Ji, Ying Guo, Huachen Wei, Wei Liu, Dapeng Li, Hong-Duo Chen
Pages: 625-629
Published online on: 29 December 2011

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Article

The selective mGluR5 agonist CHPG protects against traumatic brain injury in vitro and in vivo via ERK and Akt pathway

Tao Chen, Lei Zhang, Yan Qu, Kai Huo, XiaoFan Jiang, Zhou Fei
Pages: 630-636
Published online on: 28 December 2011

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Article

Altered miRNA expression patterns in Tff2 knock-out mice correlate with cellular pathways of neoplastic development and caloric metabolism

Aftab Ali Shah, Petra Leidinger, Andreas Keller, Anke Wendschlag, Eckart Meese, Nikolaus Blin
Pages: 637-643
Published online on: 10 January 2012

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Article

Novel RS1 mutations associated with X-linked juvenile retinoschisis

Junhui Yi, Shiqiang Li, Xiaoyun Jia, Xueshan Xiao, Panfeng Wang, Xiangming Guo, Qingjiong Zhang
Pages: 644-648
Published online on: 10 January 2012

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Article

Oridonin induces apoptosis and senescence by increasing hydrogen peroxide and glutathione depletion in colorectal cancer cells

Feng-Hou Gao, Feng Liu, Wei Wei, Li-Bin Liu, Mang-Hua Xu, Zhu-Ying Guo, Wei Li, Bin Jiang, Ying-Li Wu
Pages: 649-655
Published online on: 24 January 2012

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Article

Pattern of cancer/testis antigen expression in lung cancer patients

Yeong-Dae Kim, Hae-Rim Park, Myung-Ha Song, Dong-Hoon Shin, Chang-Hun Lee, Min-Ki Lee, Sang-Yull Lee
Pages: 656-662
Published online on: 24 January 2012

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Article

The regulatory role of microRNA-1187 in TNF-α-mediated hepatocyte apoptosis in acute liver failure

Dong Shan Yu, Fang Mei An, Bang Dong Gong, Xiao Gang Xiang, Lan Yi Lin, Hui Wang, Qing Xie
Pages: 663-668
Published online on: 17 January 2012

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Article

Analysis of the coding sequence and expression of the coiled-coil α-helical rod protein 1 gene in normal and neoplastic epithelial cervical cells

Joanna Pacholska-Bogalska, Magdalena Myga-Nowak, Katarzyna Ciepłuch, Agata Józefiak, Anna Kwaśniewska, Anna Goździcka-Józefiak
Pages: 669-676
Published online on: 03 January 2012

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Article

Cloning of the surface layer gene sllB from Bacillus sphaericus ATCC 14577 and its heterologous expression and purification

Yu-Bao Cui, Ying Zhou, Wei-Na Liu, Qing-Wen Chen, Gui-Fang Ma, Wei-Hong Shi, Yun-Gang Wang, Li Yang
Pages: 677-682
Published online on: 19 January 2012

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Article

Females with angina pectoris have altered lipoprotein metabolism with elevated cholesteryl ester transfer protein activity and impaired high-density lipoproteins-associated antioxidant enzymes

Jungho Park, Jae-Ryong Kim, Dong-Gu Shin, Kyung-Hyun Cho
Pages: 683-689
Published online on: 29 December 2011

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Article

Alternative splicing of apoptosis-related genes in imatinib-treated K562 cells identified by exon array analysis

Jing Liu, Yun Xiao, Huo-Mei Xiong, Jing Li, Bo Huang, Hai-Bin Zhang, Dan-Qin Feng, Xi-Min Chen, Xiao-Zhong Wang
Pages: 690-698
Published online on: 29 December 2011

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Article

NOD1 and NOD2 stimulation triggers innate immune responses of human periodontal ligament cells

Do-In Jeon, Se-Ra Park, Mee-Young Ahn, Sang-Gun Ahn, Jong-Hwan Park, Jung-Hoon Yoon
Pages: 699-703
Published online on: 03 January 2012

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Article

Protocadherin-10 is involved in angiogenesis and methylation correlated with multiple myeloma

Ying Li, Ze-song Yang, Jun-jun Song, Qiong Liu, Jian-bin Chen
Pages: 704-710
Published online on: 09 January 2012

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Article

Soybean glyceollins mitigate inducible nitric oxide synthase and cyclooxygenase-2 expression levels via suppression of the NF-κB signaling pathway in RAW 264.7 cells

Eun-Kyung Yoon, Hyun-Kyoung Kim, Song Cui, Yong-Hoon Kim, Sang-Han Lee
Pages: 711-717
Published online on: 12 January 2012

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

miR‑205: A dual regulator of angiogenesis in health and disease (Review)

Maria Oltra, Miriam Martínez‑Santos, Maria Ybarra, Maria Pires, Chiara Ceresoni, Clara Gomis‑Coloma, Cristina Medina‑Trillo, Javier Sancho, Jorge Barcia
Article Number: 51
Published online on: 29 December 2025

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Review Open Access

Astragaloside IV: A multipotent phytochemical for treating fibrotic diseases (Review)

Mingyu Wu, Ke Li, Jiabin Wu, Qiuyu Zhang, Xiaotong Ma, Wei Dai, Haoyang Gao, Xianyi Ding, Wenhong Wang, Weihua Xiao
Article Number: 50
Published online on: 24 December 2025

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Review Open Access

Activating transcription factors: Orchestrators of macrophage biology in pathological settings (Review)

Yue-Chen Liu, Jia-Wei Zhao, Xiong-Tao Yue, Qi-Jie Chen, Shan-Jie Rong, Shi-Wei Liu, Fei Sun, Chun-Liang Yang, Cong-Yi Wang
Article Number: 49
Published online on: 24 December 2025

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Review Open Access

Role of SIRT3 in digestive system diseases and therapeutic prospects (Review)

Jiajia Li, Qian Liu, Shun Yao, Xin Li, Li Zhang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 48
Published online on: 22 December 2025

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Article Open Access

Recombinant ADAMTS‑1 promotes muscle regeneration accompanied by downregulation of Notch signaling

Jin-Hwa Kim, Sang-Hyup Lee, Sang-Yoon Kim, Jeong-Won Kim, Ji-Soo Jeong, Eun-Hye Chung, Su-Ha Lee, Chang-Yeop Kim, Bong-Keun Choi, Je-Won Ko, Tae-Won Kim
Article Number: 47
Published online on: 22 December 2025

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A comprehensive review on pain: Model, target, therapy, and prospect (Review)

Chenyu Chang, Xutao Wu, Kejia Liu, Lei Wang, Mozili Adu, Qingyuan Lin, Huilian Huang, Qinge Ma, Rongrui Wei, Xiaoyun Wang, Wenmin Liu
Article Number: 46
Published online on: 17 December 2025

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Retraction Open Access

[Retracted] Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore

Yanbing Zhao, Yuxuan Guo, Yuqiong Chen, Shuang Liu, Nan Wu, Dalin Jia
Article Number: 45
Published online on: 15 December 2025

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Nanomaterials and exercise interventions: A synergistic approach for atherosclerosis therapy (Review)

Quanquan Zhou, Ge‑Lin Zhang, Weitong Sun, Jiayi Cai, Li-Hua Yu
Article Number: 44
Published online on: 10 December 2025

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Article Open Access

Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease

Yiyang Pan, Feng Yang, Liucan Wang, Tianshu Yang, Guangsheng Du, Cong Xu, Hua Yang, Min Yu, Weidong Xiao
Article Number: 43
Published online on: 10 December 2025

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Lactylation‑mediated ferroptosis: A novel mechanism and therapeutic prospects in human diseases (Review)

Zhengjun Lin, Yugang Zou, Songzhu Zou, Kunming Wen
Article Number: 42
Published online on: 08 December 2025

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Review Open Access

Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)

Qian Yu, Yu Kuang, Jie He, Li Yang, Xinjie Li, Hao Yu
Article Number: 41
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑493‑5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP2

Guannan Wang, Xiaosan Fang, Meng Han, Xiaoming Wang, Qiang Huang
Article Number: 40
Published online on: 08 December 2025

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Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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Article Open Access

STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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Article Open Access

HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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Article Open Access

FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Review Open Access

Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Review Open Access

Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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