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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2015 Volume 35 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Cellular crosstalk mechanism of Toll-like receptors in gingival overgrowth (Review)

Tamilselvan Subramani, Vidhya Rathnavelu, Noorjahan Banu Alitheen, Parasuraman Padmanabhan
Pages: 1151-1158
Published online on: 18 March 2015

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Article Open Access

The role of mAKAPβ in the process of cardiomyocyte hypertrophy induced by angiotensin II

Huixin Guo, Baoxin Liu, Lei Hou, Erlinda The, Gang Li, Dongzhi Wang, Qiqiang Jie, Wenliang Che, Yidong Wei
Pages: 1159-1168
Published online on: 02 March 2015

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Article Open Access

Thymosin beta 4 is associated with RUNX2 expression through the Smad and Akt signaling pathways in mouse dental epithelial cells

Hirotaka Someya, Hiroaki Fujiwara, Kengo Nagata, Hiroko Wada, Kana Hasegawa, Yurie Mikami, Akiko Jinno, Hidetaka Sakai, Kiyoshi Koyano, Tamotsu Kiyoshima
Pages: 1169-1178
Published online on: 02 March 2015

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Article Open Access

P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation

Kuang Peng, Lushan Liu, Dangheng Wei, Yuncheng Lv, Gang Wang, Wenhao Xiong, Xiaoqing Wang, Afrasyab Altaf, Lili Wang, Dan He, Hongyan Wang, Peng Qu
Pages: 1179-1188
Published online on: 09 March 2015

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Article Open Access

Association of genetic variants with hypertension in a longitudinal population-based genetic epidemiological study

Yoshiji Yamada, Kota Matsui, Ichiro Takeuchi, Mitsutoshi Oguri, Tetsuo Fujimaki
Pages: 1189-1198
Published online on: 20 March 2015

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Article Open Access

Neuroprotective effects of activated protein C on intrauterine inflammation-induced neonatal white matter injury are associated with the downregulation of fibrinogen-like protein 2/fibroleukin prothrombinase and the inhibition of pro-inflammatory cytokine expression

Sheng-Juan Jin, Yan Liu, Shi-Hua Deng, Li-Hong Liao, Tu-Lian Lin, Qin Ning, Xiao-Ping Luo
Pages: 1199-1212
Published online on: 13 March 2015

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Article Open Access

Vitamin D/VDR signaling pathway ameliorates 2,4,6-trinitrobenzene sulfonic acid-induced colitis by inhibiting intestinal epithelial apoptosis

Tong Zhu, Tian-Jing Liu, Yong-Yan Shi, Qun Zhao
Pages: 1213-1218
Published online on: 20 March 2015

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Article Open Access

Stem cells derived from human first-trimester umbilical cord have the potential to differentiate into oocyte-like cells in vitro

Xiang Hu, Hua Lu, Sheng Cao, Yan-Li Deng, Qi-Jia Li, Qian Wan, Shang-Mian Yie
Pages: 1219-1229
Published online on: 11 March 2015

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Article Open Access

Ser341Pro MYOC gene mutation in a family with primary open-angle glaucoma

Fengyun Wang, Yang Li, Lan Lan, Bo Li, Li Lin, Xiaohe Lu, Jiping Li
Pages: 1230-1236
Published online on: 13 March 2015

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Article Open Access

The inhibitory effects of Geranium thunbergii on interferon-γ- and LPS-induced inflammatory responses are mediated by Nrf2 activation

Hee-Jin Choi, Hee-Jung Choi, Mi-Ju Park, Ji-Yeon Lee, Seung-Il Jeong, Seongoo Lee, Kyun Ha Kim, Myungsoo Joo, Han-Sol Jeong, Jai-Eun Kim, Ki-Tae Ha
Pages: 1237-1245
Published online on: 06 March 2015

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Article Open Access

Keloid-derived keratinocytes acquire a fibroblast-like appearance and an enhanced invasive capacity in a hypoxic microenvironment in vitro

Xiaoyang Ma, Jia Chen, Bei Xu, Xiao Long, Han Qin, Robert Chunhua Zhao, Xiaojun Wang
Pages: 1246-1256
Published online on: 13 March 2015

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Article Open Access

ATP-sensitive potassium channels alleviate postoperative pain through JNK-dependent MCP-1 expression in spinal cord

Xiang Zhu, Jinqian Liu, Yongjing Gao, Su Cao, Shiren Shen
Pages: 1257-1265
Published online on: 17 March 2015

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Article Open Access

Downregulation of miR-518a-3p activates the NIK-dependent NF-κB pathway in colorectal cancer

L. L. Qu, L. He, X. Zhao, W. Xu
Pages: 1266-1272
Published online on: 18 March 2015

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Article Open Access

Fc gamma receptor IIb participates in maternal IgG trafficking of human placental endothelial cells

Tomoko Ishikawa, Takami Takizawa, Jun Iwaki, Takuya Mishima, Kumiko Ui-Tei, Toshiyuki Takeshita, Shigeki Matsubara, Toshihiro Takizawa
Pages: 1273-1289
Published online on: 17 March 2015

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Article Open Access

Association of genetic variants with dyslipidemia and chronic kidney disease in a longitudinal population-based genetic epidemiological study

Yoshiji Yamada, Kota Matsui, Ichiro Takeuchi, Tetsuo Fujimaki
Pages: 1290-1300
Published online on: 20 March 2015

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Article

miR-218 inhibits the invasion and migration of colon cancer cells by targeting the PI3K/Akt/mTOR signaling pathway

Xiangliang Zhang, Huijuan Shi, Hongsheng Tang, Zhiyuan Fang, Jiping Wang, Shuzhong Cui
Pages: 1301-1308
Published online on: 06 March 2015

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Article

Overexpression of COX-2 but not indoleamine 2,3-dioxygenase-1 enhances the immunosuppressive ability of human umbilical cord-derived mesenchymal stem cells

Dong Li, Yan Han, Yong Zhuang, Jinqiu Fu, Huan Liu, Qing Shi, Xiuli Ju
Pages: 1309-1316
Published online on: 13 March 2015

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Article

Downregulation of NIT2 inhibits colon cancer cell proliferation and induces cell cycle arrest through the caspase-3 and PARP pathways

Bo'an Zheng, Rui Chai, Xiaojun Yu
Pages: 1317-1322
Published online on: 04 March 2015

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Article

iTRAQ-based quantitative proteomic analysis of cerebrospinal fluid reveals NELL2 as a potential diagnostic biomarker of tuberculous meningitis

Yongtao Yang, Jun Mu, Guanghui Chen, Yuan Zhan, Jiaju Zhong, Youdong Wei, Ke Cheng, Bin Qin, Hongmin You, Peng Xie
Pages: 1323-1332
Published online on: 11 March 2015

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Article

NFATc1 activation promotes the invasion of U251 human glioblastoma multiforme cells through COX-2

Laizang Wang, Zhi Wang, Jianhua Li, Weiguang Zhang, Fubin Ren, Wu Yue
Pages: 1333-1340
Published online on: 04 March 2015

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Article

A comparative study of the proliferation and osteogenic differentiation of human periodontal ligament cells cultured on β-TCP ceramics and demineralized bone matrix with or without osteogenic inducers in vitro

Shaofeng An, Yan Gao, Xiangya Huang, Junqi Ling, Zhaohui Liu, Yin Xiao
Pages: 1341-1346
Published online on: 03 March 2015

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Article

Soluble uric acid increases NALP3 inflammasome and interleukin-1β expression in human primary renal proximal tubule epithelial cells through the Toll-like receptor 4-mediated pathway

Jing Xiao, Xiao-Li Zhang, Chensheng Fu, Rui Han, Weijun Chen, Yijun Lu, Zhibin Ye
Pages: 1347-1354
Published online on: 18 March 2015

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Article

Ras ssDNA aptamer inhibits vascular smooth muscle cell proliferation and migration through MAPK and PI3K pathways

Xiaoping Hu, Zhiwei Wang, Hongbing Wu, Wanli Jiang, Rui Hu
Pages: 1355-1361
Published online on: 16 March 2015

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Article

Peptide derived from desalinated boiled tuna extract inhibits adipogenesis through the downregulation of C/EBP-α and PPAR-γ in 3T3-L1 adipocytes

Young-Min Kim, Eun-Young Kim, In-Hye Kim, Taek-Jeong Nam
Pages: 1362-1368
Published online on: 06 March 2015

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Article

Systemic delivery of synthetic microRNA-451 is an effective therapeutic strategy for the treatment of lung cancer Retraction in /10.3892/ijmm.2016.2693

Baisong Lou, Xin Zhou
Pages: 1369-1373
Published online on: 18 March 2015

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Article

Decreased semaphorin 3A expression is associated with a poor prognosis in patients with epithelial ovarian carcinoma

Haiyan Jiang, Lei Qi, Feiran Wang, Zhichao Sun, Zhongwei Huang, Qinghua Xi
Pages: 1374-1380
Published online on: 17 March 2015

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Article

Dihydroartemisinin inhibits endothelial cell proliferation through the suppression of the ERK signaling pathway

Fengyun Dong, Hu Tian, Suhua Yan, Liqun Li, Xiaofeng Dong, Fuhai Wang, Jie Li, Changsheng Li, Zhiqun Cao, Xiaochun Liu, Ju Liu
Pages: 1381-1387
Published online on: 16 March 2015

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Article

20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol, a metabolite of ginsenoside Rb1, enhances the production of hyaluronic acid through the activation of ERK and Akt mediated by Src tyrosin kinase in human keratinocytes

Tae-Gyu Lim, Ae Ji Jeon, Ji Hye Yoon, Dasom Song, Jong-Eun Kim, Jung Yeon Kwon, Jong Rhan Kim, Nam Joo Kang, Jun-Seong Park, Myeong Hun Yeom, Deok-Kun Oh, Yoongho Lim, Charles C. Lee, Chang Yong Lee, Ki Won Lee
Pages: 1388-1394
Published online on: 02 March 2015

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Article

microRNA-214 enhances the invasion ability of breast cancer cells by targeting p53

Fang Wang, Pengwei Lv, Xinwei Liu, Mingzhi Zhu, Xinguang Qiu
Pages: 1395-1402
Published online on: 03 March 2015

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Article

Anti-inflammatory effects of methanol extract of Canarium lyi C.D. Dai & Yakovlev in RAW 264.7 macrophages and a murine model of lipopolysaccharide-induced lung injury

Ju-Mi Hong, Ok-Kyoung Kwon, In-Sik Shin, Chan-Mi Jeon, Na-Rae Shin, Joongku Lee, Sang-Hong Park, Tran The Bach, Do Van Hai, Sei-Ryang Oh, Sang-Bae Han, Kyung-Seop Ahn
Pages: 1403-1410
Published online on: 02 March 2015

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Article

Protective effect of ixerisoside A against UVB‑induced pro‑inflammatory cytokine production in human keratinocytes

Sung‑Bae Kim, Ji‑Eun Kim, Ok‑Hwa Kang, Su‑Hyun Mun, Yun‑Soo Seo, Da‑Hye Kang, Da‑Wun Yang, Shi‑Yong Ryu, Young‑Mi Lee, Dong‑Yeul Kwon
Pages: 1411-1418
Published online on: 02 March 2015

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Article

Caffeic acid phenethyl ester reduces the secretion of vascular endothelial growth factor through the inhibition of the ROS, PI3K and HIF-1α signaling pathways in human retinal pigment epithelial cells under hypoxic conditions

Sung Hwa Paeng, Won-Kyo Jung, Won Sun Park, Dae-Sung Lee, Gi-Young Kim, Yung Hyun Choi, Su-Kil Seo, Won Hee Jang, Jung Sik Choi, Young-Min Lee, Saegwang Park, Il-Whan Choi
Pages: 1419-1426
Published online on: 27 February 2015

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Article

SP600125 reduces lipopolysaccharide-induced apoptosis and restores the early-stage differentiation of osteoblasts inhibited by LPS through the MAPK pathway in MC3T3-E1 cells

Chun Guo, Sheng-Li Wang, Song-Tao Xu, Jian-Guo Wang, Guo-Hua Song
Pages: 1427-1434
Published online on: 09 March 2015

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Article

Caveolin-1 aggravates cigarette smoke extract-induced MUC5AC secretion in human airway epithelial cells

Qiao Yu, Xi Chen, Xia Fang, Qiong Chen, Chengping Hu
Pages: 1435-1442
Published online on: 11 March 2015

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Article

Toll-like receptor family members in skin fibroblasts are functional and have a higher expression compared to skin keratinocytes

Cheng Yao, Jang-Hee Oh, Dong Hun Lee, Jung-Soo Bae, Cheng Long Jin, Chi-Hyun Park, Jin Ho Chung
Pages: 1443-1450
Published online on: 18 March 2015

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Article

Association of six genetic variants with myocardial infarction

Reiko Matsuoka, Shintaro Abe, Fumitaka Tokoro, Masazumi Arai, Toshiyuki Noda, Sachiro Watanabe, Hideki Horibe, Tetsuo Fujimaki, Mitsutoshi Oguri, Kimihiko Kato, Shinya Minatoguchi, Yoshiji Yamada
Pages: 1451-1459
Published online on: 27 February 2015

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Article

IQGAP1 modulates the proliferation and migration of vascular smooth muscle cells in response to estrogen

Xianchen Huang, Yiqi Jin, Dayong Zhou, Guoxiong Xu, Jian Huang, Liming Shen
Pages: 1460-1466
Published online on: 12 March 2015

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Article

Genome-wide analysis of 5-hmC in the peripheral blood of systemic lupus erythematosus patients using an hMeDIP-chip

Weiguo Sui, Qiupei Tan, Ming Yang, Qiang Yan, Hua Lin, Minglin Ou, Wen Xue, Jiejing Chen, Tongxiang Zou, Huanyun Jing, Li Guo, Cuihui Cao, Yufeng Sun, Zhenzhen Cui, Yong Dai
Pages: 1467-1479
Published online on: 19 March 2015

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Review Open Access

Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Review Open Access

Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)

Hang Ruan, Xiao-Yan Shen, Shi-Yan Liu, Shu-Sheng Li
Article Number: 87
Published online on: 06 February 2026

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Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)

Changliang Ma, Jingxin Li, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Wencui Li, Zhiqin Deng, Zhe Zhao
Article Number: 86
Published online on: 05 February 2026

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Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling

Qin Deng, Zhongzhong Liu, Qifa Ye, Jia Liu, Zhihui Fu, Xingjian Zhang, Jun Luo, Zhongshan Lu, Pengpeng Yue, Jiansheng Xiao, Qi Xiao
Article Number: 85
Published online on: 05 February 2026

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Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Article Open Access

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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Correction Open Access

[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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