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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2015 Volume 35 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Cellular crosstalk mechanism of Toll-like receptors in gingival overgrowth (Review)

Tamilselvan Subramani, Vidhya Rathnavelu, Noorjahan Banu Alitheen, Parasuraman Padmanabhan
Pages: 1151-1158
Published online on: 18 March 2015

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Article Open Access

The role of mAKAPβ in the process of cardiomyocyte hypertrophy induced by angiotensin II

Huixin Guo, Baoxin Liu, Lei Hou, Erlinda The, Gang Li, Dongzhi Wang, Qiqiang Jie, Wenliang Che, Yidong Wei
Pages: 1159-1168
Published online on: 02 March 2015

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Article Open Access

Thymosin beta 4 is associated with RUNX2 expression through the Smad and Akt signaling pathways in mouse dental epithelial cells

Hirotaka Someya, Hiroaki Fujiwara, Kengo Nagata, Hiroko Wada, Kana Hasegawa, Yurie Mikami, Akiko Jinno, Hidetaka Sakai, Kiyoshi Koyano, Tamotsu Kiyoshima
Pages: 1169-1178
Published online on: 02 March 2015

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Article Open Access

P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation

Kuang Peng, Lushan Liu, Dangheng Wei, Yuncheng Lv, Gang Wang, Wenhao Xiong, Xiaoqing Wang, Afrasyab Altaf, Lili Wang, Dan He, Hongyan Wang, Peng Qu
Pages: 1179-1188
Published online on: 09 March 2015

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Article Open Access

Association of genetic variants with hypertension in a longitudinal population-based genetic epidemiological study

Yoshiji Yamada, Kota Matsui, Ichiro Takeuchi, Mitsutoshi Oguri, Tetsuo Fujimaki
Pages: 1189-1198
Published online on: 20 March 2015

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Article Open Access

Neuroprotective effects of activated protein C on intrauterine inflammation-induced neonatal white matter injury are associated with the downregulation of fibrinogen-like protein 2/fibroleukin prothrombinase and the inhibition of pro-inflammatory cytokine expression

Sheng-Juan Jin, Yan Liu, Shi-Hua Deng, Li-Hong Liao, Tu-Lian Lin, Qin Ning, Xiao-Ping Luo
Pages: 1199-1212
Published online on: 13 March 2015

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Article Open Access

Vitamin D/VDR signaling pathway ameliorates 2,4,6-trinitrobenzene sulfonic acid-induced colitis by inhibiting intestinal epithelial apoptosis

Tong Zhu, Tian-Jing Liu, Yong-Yan Shi, Qun Zhao
Pages: 1213-1218
Published online on: 20 March 2015

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Article Open Access

Stem cells derived from human first-trimester umbilical cord have the potential to differentiate into oocyte-like cells in vitro

Xiang Hu, Hua Lu, Sheng Cao, Yan-Li Deng, Qi-Jia Li, Qian Wan, Shang-Mian Yie
Pages: 1219-1229
Published online on: 11 March 2015

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Article Open Access

Ser341Pro MYOC gene mutation in a family with primary open-angle glaucoma

Fengyun Wang, Yang Li, Lan Lan, Bo Li, Li Lin, Xiaohe Lu, Jiping Li
Pages: 1230-1236
Published online on: 13 March 2015

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Article Open Access

The inhibitory effects of Geranium thunbergii on interferon-γ- and LPS-induced inflammatory responses are mediated by Nrf2 activation

Hee-Jin Choi, Hee-Jung Choi, Mi-Ju Park, Ji-Yeon Lee, Seung-Il Jeong, Seongoo Lee, Kyun Ha Kim, Myungsoo Joo, Han-Sol Jeong, Jai-Eun Kim, Ki-Tae Ha
Pages: 1237-1245
Published online on: 06 March 2015

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Article Open Access

Keloid-derived keratinocytes acquire a fibroblast-like appearance and an enhanced invasive capacity in a hypoxic microenvironment in vitro

Xiaoyang Ma, Jia Chen, Bei Xu, Xiao Long, Han Qin, Robert Chunhua Zhao, Xiaojun Wang
Pages: 1246-1256
Published online on: 13 March 2015

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Article Open Access

ATP-sensitive potassium channels alleviate postoperative pain through JNK-dependent MCP-1 expression in spinal cord

Xiang Zhu, Jinqian Liu, Yongjing Gao, Su Cao, Shiren Shen
Pages: 1257-1265
Published online on: 17 March 2015

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Article Open Access

Downregulation of miR-518a-3p activates the NIK-dependent NF-κB pathway in colorectal cancer

L. L. Qu, L. He, X. Zhao, W. Xu
Pages: 1266-1272
Published online on: 18 March 2015

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Article Open Access

Fc gamma receptor IIb participates in maternal IgG trafficking of human placental endothelial cells

Tomoko Ishikawa, Takami Takizawa, Jun Iwaki, Takuya Mishima, Kumiko Ui-Tei, Toshiyuki Takeshita, Shigeki Matsubara, Toshihiro Takizawa
Pages: 1273-1289
Published online on: 17 March 2015

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Article Open Access

Association of genetic variants with dyslipidemia and chronic kidney disease in a longitudinal population-based genetic epidemiological study

Yoshiji Yamada, Kota Matsui, Ichiro Takeuchi, Tetsuo Fujimaki
Pages: 1290-1300
Published online on: 20 March 2015

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Article

miR-218 inhibits the invasion and migration of colon cancer cells by targeting the PI3K/Akt/mTOR signaling pathway

Xiangliang Zhang, Huijuan Shi, Hongsheng Tang, Zhiyuan Fang, Jiping Wang, Shuzhong Cui
Pages: 1301-1308
Published online on: 06 March 2015

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Article

Overexpression of COX-2 but not indoleamine 2,3-dioxygenase-1 enhances the immunosuppressive ability of human umbilical cord-derived mesenchymal stem cells

Dong Li, Yan Han, Yong Zhuang, Jinqiu Fu, Huan Liu, Qing Shi, Xiuli Ju
Pages: 1309-1316
Published online on: 13 March 2015

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Article

Downregulation of NIT2 inhibits colon cancer cell proliferation and induces cell cycle arrest through the caspase-3 and PARP pathways

Bo'an Zheng, Rui Chai, Xiaojun Yu
Pages: 1317-1322
Published online on: 04 March 2015

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Article

iTRAQ-based quantitative proteomic analysis of cerebrospinal fluid reveals NELL2 as a potential diagnostic biomarker of tuberculous meningitis

Yongtao Yang, Jun Mu, Guanghui Chen, Yuan Zhan, Jiaju Zhong, Youdong Wei, Ke Cheng, Bin Qin, Hongmin You, Peng Xie
Pages: 1323-1332
Published online on: 11 March 2015

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Article

NFATc1 activation promotes the invasion of U251 human glioblastoma multiforme cells through COX-2

Laizang Wang, Zhi Wang, Jianhua Li, Weiguang Zhang, Fubin Ren, Wu Yue
Pages: 1333-1340
Published online on: 04 March 2015

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Article

A comparative study of the proliferation and osteogenic differentiation of human periodontal ligament cells cultured on β-TCP ceramics and demineralized bone matrix with or without osteogenic inducers in vitro

Shaofeng An, Yan Gao, Xiangya Huang, Junqi Ling, Zhaohui Liu, Yin Xiao
Pages: 1341-1346
Published online on: 03 March 2015

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Article

Soluble uric acid increases NALP3 inflammasome and interleukin-1β expression in human primary renal proximal tubule epithelial cells through the Toll-like receptor 4-mediated pathway

Jing Xiao, Xiao-Li Zhang, Chensheng Fu, Rui Han, Weijun Chen, Yijun Lu, Zhibin Ye
Pages: 1347-1354
Published online on: 18 March 2015

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Article

Ras ssDNA aptamer inhibits vascular smooth muscle cell proliferation and migration through MAPK and PI3K pathways

Xiaoping Hu, Zhiwei Wang, Hongbing Wu, Wanli Jiang, Rui Hu
Pages: 1355-1361
Published online on: 16 March 2015

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Article

Peptide derived from desalinated boiled tuna extract inhibits adipogenesis through the downregulation of C/EBP-α and PPAR-γ in 3T3-L1 adipocytes

Young-Min Kim, Eun-Young Kim, In-Hye Kim, Taek-Jeong Nam
Pages: 1362-1368
Published online on: 06 March 2015

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Article

Systemic delivery of synthetic microRNA-451 is an effective therapeutic strategy for the treatment of lung cancer Retraction in /10.3892/ijmm.2016.2693

Baisong Lou, Xin Zhou
Pages: 1369-1373
Published online on: 18 March 2015

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Article

Decreased semaphorin 3A expression is associated with a poor prognosis in patients with epithelial ovarian carcinoma

Haiyan Jiang, Lei Qi, Feiran Wang, Zhichao Sun, Zhongwei Huang, Qinghua Xi
Pages: 1374-1380
Published online on: 17 March 2015

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Article

Dihydroartemisinin inhibits endothelial cell proliferation through the suppression of the ERK signaling pathway

Fengyun Dong, Hu Tian, Suhua Yan, Liqun Li, Xiaofeng Dong, Fuhai Wang, Jie Li, Changsheng Li, Zhiqun Cao, Xiaochun Liu, Ju Liu
Pages: 1381-1387
Published online on: 16 March 2015

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Article

20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol, a metabolite of ginsenoside Rb1, enhances the production of hyaluronic acid through the activation of ERK and Akt mediated by Src tyrosin kinase in human keratinocytes

Tae-Gyu Lim, Ae Ji Jeon, Ji Hye Yoon, Dasom Song, Jong-Eun Kim, Jung Yeon Kwon, Jong Rhan Kim, Nam Joo Kang, Jun-Seong Park, Myeong Hun Yeom, Deok-Kun Oh, Yoongho Lim, Charles C. Lee, Chang Yong Lee, Ki Won Lee
Pages: 1388-1394
Published online on: 02 March 2015

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Article

microRNA-214 enhances the invasion ability of breast cancer cells by targeting p53

Fang Wang, Pengwei Lv, Xinwei Liu, Mingzhi Zhu, Xinguang Qiu
Pages: 1395-1402
Published online on: 03 March 2015

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Article

Anti-inflammatory effects of methanol extract of Canarium lyi C.D. Dai & Yakovlev in RAW 264.7 macrophages and a murine model of lipopolysaccharide-induced lung injury

Ju-Mi Hong, Ok-Kyoung Kwon, In-Sik Shin, Chan-Mi Jeon, Na-Rae Shin, Joongku Lee, Sang-Hong Park, Tran The Bach, Do Van Hai, Sei-Ryang Oh, Sang-Bae Han, Kyung-Seop Ahn
Pages: 1403-1410
Published online on: 02 March 2015

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Article

Protective effect of ixerisoside A against UVB‑induced pro‑inflammatory cytokine production in human keratinocytes

Sung‑Bae Kim, Ji‑Eun Kim, Ok‑Hwa Kang, Su‑Hyun Mun, Yun‑Soo Seo, Da‑Hye Kang, Da‑Wun Yang, Shi‑Yong Ryu, Young‑Mi Lee, Dong‑Yeul Kwon
Pages: 1411-1418
Published online on: 02 March 2015

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Article

Caffeic acid phenethyl ester reduces the secretion of vascular endothelial growth factor through the inhibition of the ROS, PI3K and HIF-1α signaling pathways in human retinal pigment epithelial cells under hypoxic conditions

Sung Hwa Paeng, Won-Kyo Jung, Won Sun Park, Dae-Sung Lee, Gi-Young Kim, Yung Hyun Choi, Su-Kil Seo, Won Hee Jang, Jung Sik Choi, Young-Min Lee, Saegwang Park, Il-Whan Choi
Pages: 1419-1426
Published online on: 27 February 2015

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Article

SP600125 reduces lipopolysaccharide-induced apoptosis and restores the early-stage differentiation of osteoblasts inhibited by LPS through the MAPK pathway in MC3T3-E1 cells

Chun Guo, Sheng-Li Wang, Song-Tao Xu, Jian-Guo Wang, Guo-Hua Song
Pages: 1427-1434
Published online on: 09 March 2015

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Article

Caveolin-1 aggravates cigarette smoke extract-induced MUC5AC secretion in human airway epithelial cells

Qiao Yu, Xi Chen, Xia Fang, Qiong Chen, Chengping Hu
Pages: 1435-1442
Published online on: 11 March 2015

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Article

Toll-like receptor family members in skin fibroblasts are functional and have a higher expression compared to skin keratinocytes

Cheng Yao, Jang-Hee Oh, Dong Hun Lee, Jung-Soo Bae, Cheng Long Jin, Chi-Hyun Park, Jin Ho Chung
Pages: 1443-1450
Published online on: 18 March 2015

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Article

Association of six genetic variants with myocardial infarction

Reiko Matsuoka, Shintaro Abe, Fumitaka Tokoro, Masazumi Arai, Toshiyuki Noda, Sachiro Watanabe, Hideki Horibe, Tetsuo Fujimaki, Mitsutoshi Oguri, Kimihiko Kato, Shinya Minatoguchi, Yoshiji Yamada
Pages: 1451-1459
Published online on: 27 February 2015

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Article

IQGAP1 modulates the proliferation and migration of vascular smooth muscle cells in response to estrogen

Xianchen Huang, Yiqi Jin, Dayong Zhou, Guoxiong Xu, Jian Huang, Liming Shen
Pages: 1460-1466
Published online on: 12 March 2015

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Article

Genome-wide analysis of 5-hmC in the peripheral blood of systemic lupus erythematosus patients using an hMeDIP-chip

Weiguo Sui, Qiupei Tan, Ming Yang, Qiang Yan, Hua Lin, Minglin Ou, Wen Xue, Jiejing Chen, Tongxiang Zou, Huanyun Jing, Li Guo, Cuihui Cao, Yufeng Sun, Zhenzhen Cui, Yong Dai
Pages: 1467-1479
Published online on: 19 March 2015

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Journal Cover
January-2026 Volume 57 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review)

Zhi Li, Xiaolei Liu, Hesong Zeng
Article Number: 30
Published online on: 24 November 2025

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Retraction Open Access

[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

Jin-Long Chen, Fang Chen, Ting-Ting Zhang, Nai-Fu Liu
Article Number: 29
Published online on: 24 November 2025

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Article Open Access

METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner

Yang Wang, Yihao Tian, Gang Yao
Article Number: 28
Published online on: 20 November 2025

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Review Open Access

Decoding structural birth defects through genomic landscapes: Innovative frameworks for diagnosis (Review)

Ruihao Xu, Haoming Ren, Zhengwei Yuan, Wanqi Huang, Hui Gu
Article Number: 27
Published online on: 20 November 2025

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Article Open Access

MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice

Dan Chen, Hui-Min Zhao, Xiao-Lin Sun, Zhi-Xuan Xing, Sheng-Peng Li, Shuai-Chao Li, Ya-Xian Wu, Qing-Feng Pang, Jian-Feng Huang
Article Number: 26
Published online on: 18 November 2025

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Article Open Access

Synergistic effects of Akebia saponin D and Semaglutide on diabetic nephropathy and osteoporosis via the Klotho‑p53 signaling axis

Qian Zhang, Dan Wang, Hongxia Jia, Zongji Zheng, Liyan Lin, Linna Li, Ling Wang, Yaoming Xue
Article Number: 25
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑103 modulates tumor progression by targeting KLF7 in non‑small cell lung cancer

Ke Li, Conghu Yuan
Article Number: 24
Published online on: 17 November 2025

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Article

Comparative analysis of pan MHC‑I epitopes immunoreactivity on Hantaan virus nucleocapsid protein

Zhikui Li, Weijie Ding, Yubo Sun, Chenfeng Tian, Shuaishuai Fu, Fei Shi, Zhenchi Fang, Yuanzhe Li, Jianchang Li, Sirui Cai, Haobo Kang, Baozeng Sun, Junqi Zhang, Yuanjie Sun, Shuya Yang, Yusi Zhang, Chunmei Zhang, Yun Zhang, Xiyang Zhang, Kun Yang, Dongbo Jiang
Article Number: 23
Published online on: 14 November 2025

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Article Open Access

Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy

Boya Zhang, Defeng Kong, Siji Chen, Xuewu Sun, Hao Cheng
Article Number: 22
Published online on: 14 November 2025

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Article Open Access

Targeting p38 MAPK signaling pathway: 
Quercetin as a novel therapy for TMJ synovitis

Mosha Cheng, Yuhe Guan, Xiaotao Xin, Xin Yi, Yi Liu
Article Number: 21
Published online on: 13 November 2025

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Review Open Access

Lipid droplets in astrocytes: Key organelles for CNS homeostasis and disease (Review)

Yuchen Wang, Boxuan Wang, Jinchao Hou, Xiaodong Huo, Chenlin Liu, Ruili Guan, Honggang Chen, Yang Zhou, Jianbin Zhang, Congcong Zhuang, Yuankang Zou
Article Number: 20
Published online on: 13 November 2025

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Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)

Peiyu Li, Yinghui Li, Qian Meng, Jie Wang, Kun Wang, Sumin Yang
Article Number: 19
Published online on: 13 November 2025

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Article Open Access

Elevated FTO alleviates sepsis‑induced acute kidney injury by regulating macrophage inflammatory phenotypes

Xiaona Chen, Ziqi Sun, Jiabo Chen, Jinquan Zhang, Zeyu Liu, Zhengzheng Yan, Quan Li, Zhixia Chen
Article Number: 18
Published online on: 12 November 2025

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Correction Open Access

[Corrigendum]  Suppression of PAX6 promotes cell proliferation and inhibits apoptosis in human retinoblastoma cells

Bo Meng, Yisong Wang, Bin Li
Article Number: 17
Published online on: 10 November 2025

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Review Open Access

Microbial short chain fatty acids: Effective histone deacetylase inhibitors in immune regulation (Review)

Jing Wang, Qin Zhao, Shuwan Zhang, Jia Liu, Xingyue Fan, Bin Han, Yaqin Hou, Xiaopeng Ai
Article Number: 16
Published online on: 05 November 2025

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High‑fat diet and cognitive dysfunction: Mechanistic insights into diet‑induced neurodegeneration (Review)

Min You, Fan Wu, Feng Xiong, Xue-Fei Hu, Huan Wu, Li Zhou, Hong-Xing Zhang
Article Number: 15
Published online on: 05 November 2025

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ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model

Shuang Dou, Zhijun Li, Boyao Zheng, Zhenyu Ren, Hai Wang, Qing Zuo, Fang Fang, Yuehong Zhuang
Article Number: 14
Published online on: 05 November 2025

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Review Open Access

Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)

Chaowei Zhang, Yuxuan Han, Weiyi Yao, Qing Hong, Na Chen
Article Number: 13
Published online on: 04 November 2025

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Review Open Access

β‑hydroxybutyric acid as a potential therapeutic metabolite for type 2 diabetes mellitus (Review)

Xianyi Ding, Jiabin Wu, Lian Wang, Ke Li, Haoyang Gao, Mingyu Wu, Qiuyu Zhang, Ruonan Han, Wenhong Wang, Weihua Xiao
Article Number: 12
Published online on: 03 November 2025

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Review

Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)

Xunjie Jian, Chang Cheng, Wenjie Lu, Hui Peng, Diqi Yang
Article Number: 11
Published online on: 03 November 2025

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Review Open Access

Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)

Xitong Zhao, Pengqin Wang
Article Number: 10
Published online on: 03 November 2025

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Expression of Concern Open Access

[Expression of Concern]  CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF‑κB pathway

Linlin Xiao, Man Qu, Lulu Chen, Mingli Xiang, Qian Long, Jianguo Liu, Xiaoyan Guan, Chengcheng Liao
Article Number: 8
Published online on: 27 October 2025

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Review Open Access

Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)

Tao Duan, Hanhai Mao, Xingyue Jiang, Ying Tian, Jidong Zhang, Jun Tan
Article Number: 7
Published online on: 27 October 2025

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Retraction Open Access

[Retracted] Effects of miR‑106b‑3p on cell proliferation and epithelial‑mesenchymal transition, and targeting of ZNRF3 in esophageal squamous cell carcinoma

Guanen Qiao, Chenguang Dai, Yang He, Junjie Shi, Chunfang Xu
Article Number: 6
Published online on: 27 October 2025

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Review Open Access

Immune and metabolic remodeling following bariatric surgery: Implications for targeted immunotherapy (Review)

Yiming Shao, Ke Song, Ruixin Yu, He Xiao, Chengjun Li, Yuling Deng, Yuan Zhang, Yixing Ren
Article Number: 5
Published online on: 24 October 2025

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Article Open Access

Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer

Chuanxi Lai, Xiya Jia, Yiyi Chen, Kangke Chen, Fei Wang, Qiqi Zhang, Xiaonan Xiang, Zhe-Sheng Chen, Lingna Xu, Sheng Dai
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis

Weichao Sun, Yi Liao, Jianguo Feng, Jianhui Liang, Qifei He, Yinxing Cui, Dixi Huang, Houyin Shi, Wei You, Wei Sun, Qian Yi
Article Number: 3
Published online on: 23 October 2025

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Review

Importance of B cells (Review)

Zhiyuan Liu, Haoran Dai, Xiaoyu Cui, Yeping Liu, Zhaocheng Dong
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Hypoxic preconditioned bone mesenchymal stem cells ameliorate spinal cord injury in rats via improved survival and migration

Weiheng Wang, Xiaodong Huang, Wenbo Lin, Yuanyuan Qiu, Yunfei He, Jiangming Yu, Yanhai Xi, Xiaojian Ye
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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Article Open Access

STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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Article Open Access

HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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Article Open Access

FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Review Open Access

Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Review Open Access

Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Review Open Access

Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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