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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2015 Volume 35 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Cellular crosstalk mechanism of Toll-like receptors in gingival overgrowth (Review)

Tamilselvan Subramani, Vidhya Rathnavelu, Noorjahan Banu Alitheen, Parasuraman Padmanabhan
Pages: 1151-1158
Published online on: 18 March 2015

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Article Open Access

The role of mAKAPβ in the process of cardiomyocyte hypertrophy induced by angiotensin II

Huixin Guo, Baoxin Liu, Lei Hou, Erlinda The, Gang Li, Dongzhi Wang, Qiqiang Jie, Wenliang Che, Yidong Wei
Pages: 1159-1168
Published online on: 02 March 2015

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Article Open Access

Thymosin beta 4 is associated with RUNX2 expression through the Smad and Akt signaling pathways in mouse dental epithelial cells

Hirotaka Someya, Hiroaki Fujiwara, Kengo Nagata, Hiroko Wada, Kana Hasegawa, Yurie Mikami, Akiko Jinno, Hidetaka Sakai, Kiyoshi Koyano, Tamotsu Kiyoshima
Pages: 1169-1178
Published online on: 02 March 2015

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Article Open Access

P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation

Kuang Peng, Lushan Liu, Dangheng Wei, Yuncheng Lv, Gang Wang, Wenhao Xiong, Xiaoqing Wang, Afrasyab Altaf, Lili Wang, Dan He, Hongyan Wang, Peng Qu
Pages: 1179-1188
Published online on: 09 March 2015

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Article Open Access

Association of genetic variants with hypertension in a longitudinal population-based genetic epidemiological study

Yoshiji Yamada, Kota Matsui, Ichiro Takeuchi, Mitsutoshi Oguri, Tetsuo Fujimaki
Pages: 1189-1198
Published online on: 20 March 2015

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Article Open Access

Neuroprotective effects of activated protein C on intrauterine inflammation-induced neonatal white matter injury are associated with the downregulation of fibrinogen-like protein 2/fibroleukin prothrombinase and the inhibition of pro-inflammatory cytokine expression

Sheng-Juan Jin, Yan Liu, Shi-Hua Deng, Li-Hong Liao, Tu-Lian Lin, Qin Ning, Xiao-Ping Luo
Pages: 1199-1212
Published online on: 13 March 2015

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Article Open Access

Vitamin D/VDR signaling pathway ameliorates 2,4,6-trinitrobenzene sulfonic acid-induced colitis by inhibiting intestinal epithelial apoptosis

Tong Zhu, Tian-Jing Liu, Yong-Yan Shi, Qun Zhao
Pages: 1213-1218
Published online on: 20 March 2015

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Article Open Access

Stem cells derived from human first-trimester umbilical cord have the potential to differentiate into oocyte-like cells in vitro

Xiang Hu, Hua Lu, Sheng Cao, Yan-Li Deng, Qi-Jia Li, Qian Wan, Shang-Mian Yie
Pages: 1219-1229
Published online on: 11 March 2015

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Article Open Access

Ser341Pro MYOC gene mutation in a family with primary open-angle glaucoma

Fengyun Wang, Yang Li, Lan Lan, Bo Li, Li Lin, Xiaohe Lu, Jiping Li
Pages: 1230-1236
Published online on: 13 March 2015

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Article Open Access

The inhibitory effects of Geranium thunbergii on interferon-γ- and LPS-induced inflammatory responses are mediated by Nrf2 activation

Hee-Jin Choi, Hee-Jung Choi, Mi-Ju Park, Ji-Yeon Lee, Seung-Il Jeong, Seongoo Lee, Kyun Ha Kim, Myungsoo Joo, Han-Sol Jeong, Jai-Eun Kim, Ki-Tae Ha
Pages: 1237-1245
Published online on: 06 March 2015

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Article Open Access

Keloid-derived keratinocytes acquire a fibroblast-like appearance and an enhanced invasive capacity in a hypoxic microenvironment in vitro

Xiaoyang Ma, Jia Chen, Bei Xu, Xiao Long, Han Qin, Robert Chunhua Zhao, Xiaojun Wang
Pages: 1246-1256
Published online on: 13 March 2015

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Article Open Access

ATP-sensitive potassium channels alleviate postoperative pain through JNK-dependent MCP-1 expression in spinal cord

Xiang Zhu, Jinqian Liu, Yongjing Gao, Su Cao, Shiren Shen
Pages: 1257-1265
Published online on: 17 March 2015

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Article Open Access

Downregulation of miR-518a-3p activates the NIK-dependent NF-κB pathway in colorectal cancer

L. L. Qu, L. He, X. Zhao, W. Xu
Pages: 1266-1272
Published online on: 18 March 2015

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Article Open Access

Fc gamma receptor IIb participates in maternal IgG trafficking of human placental endothelial cells

Tomoko Ishikawa, Takami Takizawa, Jun Iwaki, Takuya Mishima, Kumiko Ui-Tei, Toshiyuki Takeshita, Shigeki Matsubara, Toshihiro Takizawa
Pages: 1273-1289
Published online on: 17 March 2015

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Article Open Access

Association of genetic variants with dyslipidemia and chronic kidney disease in a longitudinal population-based genetic epidemiological study

Yoshiji Yamada, Kota Matsui, Ichiro Takeuchi, Tetsuo Fujimaki
Pages: 1290-1300
Published online on: 20 March 2015

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Article

miR-218 inhibits the invasion and migration of colon cancer cells by targeting the PI3K/Akt/mTOR signaling pathway

Xiangliang Zhang, Huijuan Shi, Hongsheng Tang, Zhiyuan Fang, Jiping Wang, Shuzhong Cui
Pages: 1301-1308
Published online on: 06 March 2015

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Article

Overexpression of COX-2 but not indoleamine 2,3-dioxygenase-1 enhances the immunosuppressive ability of human umbilical cord-derived mesenchymal stem cells

Dong Li, Yan Han, Yong Zhuang, Jinqiu Fu, Huan Liu, Qing Shi, Xiuli Ju
Pages: 1309-1316
Published online on: 13 March 2015

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Article

Downregulation of NIT2 inhibits colon cancer cell proliferation and induces cell cycle arrest through the caspase-3 and PARP pathways

Bo'an Zheng, Rui Chai, Xiaojun Yu
Pages: 1317-1322
Published online on: 04 March 2015

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Article

iTRAQ-based quantitative proteomic analysis of cerebrospinal fluid reveals NELL2 as a potential diagnostic biomarker of tuberculous meningitis

Yongtao Yang, Jun Mu, Guanghui Chen, Yuan Zhan, Jiaju Zhong, Youdong Wei, Ke Cheng, Bin Qin, Hongmin You, Peng Xie
Pages: 1323-1332
Published online on: 11 March 2015

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Article

NFATc1 activation promotes the invasion of U251 human glioblastoma multiforme cells through COX-2

Laizang Wang, Zhi Wang, Jianhua Li, Weiguang Zhang, Fubin Ren, Wu Yue
Pages: 1333-1340
Published online on: 04 March 2015

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Article

A comparative study of the proliferation and osteogenic differentiation of human periodontal ligament cells cultured on β-TCP ceramics and demineralized bone matrix with or without osteogenic inducers in vitro

Shaofeng An, Yan Gao, Xiangya Huang, Junqi Ling, Zhaohui Liu, Yin Xiao
Pages: 1341-1346
Published online on: 03 March 2015

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Article

Soluble uric acid increases NALP3 inflammasome and interleukin-1β expression in human primary renal proximal tubule epithelial cells through the Toll-like receptor 4-mediated pathway

Jing Xiao, Xiao-Li Zhang, Chensheng Fu, Rui Han, Weijun Chen, Yijun Lu, Zhibin Ye
Pages: 1347-1354
Published online on: 18 March 2015

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Article

Ras ssDNA aptamer inhibits vascular smooth muscle cell proliferation and migration through MAPK and PI3K pathways

Xiaoping Hu, Zhiwei Wang, Hongbing Wu, Wanli Jiang, Rui Hu
Pages: 1355-1361
Published online on: 16 March 2015

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Article

Peptide derived from desalinated boiled tuna extract inhibits adipogenesis through the downregulation of C/EBP-α and PPAR-γ in 3T3-L1 adipocytes

Young-Min Kim, Eun-Young Kim, In-Hye Kim, Taek-Jeong Nam
Pages: 1362-1368
Published online on: 06 March 2015

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Article

Systemic delivery of synthetic microRNA-451 is an effective therapeutic strategy for the treatment of lung cancer Retraction in /10.3892/ijmm.2016.2693

Baisong Lou, Xin Zhou
Pages: 1369-1373
Published online on: 18 March 2015

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Article

Decreased semaphorin 3A expression is associated with a poor prognosis in patients with epithelial ovarian carcinoma

Haiyan Jiang, Lei Qi, Feiran Wang, Zhichao Sun, Zhongwei Huang, Qinghua Xi
Pages: 1374-1380
Published online on: 17 March 2015

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Article

Dihydroartemisinin inhibits endothelial cell proliferation through the suppression of the ERK signaling pathway

Fengyun Dong, Hu Tian, Suhua Yan, Liqun Li, Xiaofeng Dong, Fuhai Wang, Jie Li, Changsheng Li, Zhiqun Cao, Xiaochun Liu, Ju Liu
Pages: 1381-1387
Published online on: 16 March 2015

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Article

20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol, a metabolite of ginsenoside Rb1, enhances the production of hyaluronic acid through the activation of ERK and Akt mediated by Src tyrosin kinase in human keratinocytes

Tae-Gyu Lim, Ae Ji Jeon, Ji Hye Yoon, Dasom Song, Jong-Eun Kim, Jung Yeon Kwon, Jong Rhan Kim, Nam Joo Kang, Jun-Seong Park, Myeong Hun Yeom, Deok-Kun Oh, Yoongho Lim, Charles C. Lee, Chang Yong Lee, Ki Won Lee
Pages: 1388-1394
Published online on: 02 March 2015

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Article

microRNA-214 enhances the invasion ability of breast cancer cells by targeting p53

Fang Wang, Pengwei Lv, Xinwei Liu, Mingzhi Zhu, Xinguang Qiu
Pages: 1395-1402
Published online on: 03 March 2015

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Article

Anti-inflammatory effects of methanol extract of Canarium lyi C.D. Dai & Yakovlev in RAW 264.7 macrophages and a murine model of lipopolysaccharide-induced lung injury

Ju-Mi Hong, Ok-Kyoung Kwon, In-Sik Shin, Chan-Mi Jeon, Na-Rae Shin, Joongku Lee, Sang-Hong Park, Tran The Bach, Do Van Hai, Sei-Ryang Oh, Sang-Bae Han, Kyung-Seop Ahn
Pages: 1403-1410
Published online on: 02 March 2015

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Article

Protective effect of ixerisoside A against UVB‑induced pro‑inflammatory cytokine production in human keratinocytes

Sung‑Bae Kim, Ji‑Eun Kim, Ok‑Hwa Kang, Su‑Hyun Mun, Yun‑Soo Seo, Da‑Hye Kang, Da‑Wun Yang, Shi‑Yong Ryu, Young‑Mi Lee, Dong‑Yeul Kwon
Pages: 1411-1418
Published online on: 02 March 2015

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Article

Caffeic acid phenethyl ester reduces the secretion of vascular endothelial growth factor through the inhibition of the ROS, PI3K and HIF-1α signaling pathways in human retinal pigment epithelial cells under hypoxic conditions

Sung Hwa Paeng, Won-Kyo Jung, Won Sun Park, Dae-Sung Lee, Gi-Young Kim, Yung Hyun Choi, Su-Kil Seo, Won Hee Jang, Jung Sik Choi, Young-Min Lee, Saegwang Park, Il-Whan Choi
Pages: 1419-1426
Published online on: 27 February 2015

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Article

SP600125 reduces lipopolysaccharide-induced apoptosis and restores the early-stage differentiation of osteoblasts inhibited by LPS through the MAPK pathway in MC3T3-E1 cells

Chun Guo, Sheng-Li Wang, Song-Tao Xu, Jian-Guo Wang, Guo-Hua Song
Pages: 1427-1434
Published online on: 09 March 2015

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Article

Caveolin-1 aggravates cigarette smoke extract-induced MUC5AC secretion in human airway epithelial cells

Qiao Yu, Xi Chen, Xia Fang, Qiong Chen, Chengping Hu
Pages: 1435-1442
Published online on: 11 March 2015

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Article

Toll-like receptor family members in skin fibroblasts are functional and have a higher expression compared to skin keratinocytes

Cheng Yao, Jang-Hee Oh, Dong Hun Lee, Jung-Soo Bae, Cheng Long Jin, Chi-Hyun Park, Jin Ho Chung
Pages: 1443-1450
Published online on: 18 March 2015

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Article

Association of six genetic variants with myocardial infarction

Reiko Matsuoka, Shintaro Abe, Fumitaka Tokoro, Masazumi Arai, Toshiyuki Noda, Sachiro Watanabe, Hideki Horibe, Tetsuo Fujimaki, Mitsutoshi Oguri, Kimihiko Kato, Shinya Minatoguchi, Yoshiji Yamada
Pages: 1451-1459
Published online on: 27 February 2015

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Article

IQGAP1 modulates the proliferation and migration of vascular smooth muscle cells in response to estrogen

Xianchen Huang, Yiqi Jin, Dayong Zhou, Guoxiong Xu, Jian Huang, Liming Shen
Pages: 1460-1466
Published online on: 12 March 2015

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Article

Genome-wide analysis of 5-hmC in the peripheral blood of systemic lupus erythematosus patients using an hMeDIP-chip

Weiguo Sui, Qiupei Tan, Ming Yang, Qiang Yan, Hua Lin, Minglin Ou, Wen Xue, Jiejing Chen, Tongxiang Zou, Huanyun Jing, Li Guo, Cuihui Cao, Yufeng Sun, Zhenzhen Cui, Yong Dai
Pages: 1467-1479
Published online on: 19 March 2015

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Journal Cover
July-2026 Volume 58 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Sex differences in cardiovascular‑kidney‑metabolic syndrome: From pathogenesis to treatment response (Review)

Yanqin Fan, Hongtu Hu, Jing Cheng
Article Number: 202
Published online on: 27 May 2026

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Retraction Open Access

[Retracted] BAMBI inhibits inflammation through the activation of autophagy in experimental spinal cord injury

Yin Yang, Chunyang Guo, Bo Liao, Junjun Cao, Chen Liang, Xijing He
Article Number: 201
Published online on: 25 May 2026

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Article Open Access

Integrative transcriptomic analysis unveils FXR as a key regulator of intestinal stemness and inflammation in ulcerative colitis

Hao Lin, Xinran Cheng, Yangyang Ren, Yongmei Zhang, Weixu Chen, Qingyan Lu, Yiqing Tian
Article Number: 200
Published online on: 22 May 2026

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Article Open Access

Ginsenoside Rg3 potentiates cisplatin antitumor activity while mitigating nephrotoxicity through SIRT1‑mediated suppression of the NLRP3 inflammasome

Jinghui Zhai, Yueming Zhang, Jiawei Gong, Li Fu, Sixi Zhang
Article Number: 199
Published online on: 22 May 2026

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Article Open Access

Identification of diagnostic markers for diabetic kidney disease by weighted gene co‑expression network analysis and machine learning

Qiming Xu, Chunjing Xu, Ziyang Liu, Jianrao Lu, Jing Hu, Lin Liao
Article Number: 198
Published online on: 21 May 2026

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Article Open Access

CTRP3 alleviates neuropathic pain by improving mitochondrial biogenesis and mitochondrial unfolded protein response via spinal SIRT1 in rats

Tianzhu Liu, Longqing Zhang, Wei Mei
Article Number: 197
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Activated Wnt signaling induces myofibroblast differentiation of mesenchymal stem cells, contributing to pulmonary fibrosis

Zhaorui Sun, Cong Wang, Chaowen Shi, Fangfang Sun, Xiaomeng Xu, Weiping Qian, Shinan Nie, Xiaodong Han
Article Number: 196
Published online on: 20 May 2026

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Article Open Access

Ganoderma lucidum polysaccharides improve liver metabolic disorders by modulating gut microbiota of ovariectomized mice

Xin Jin, Xuan Liu, Yun-Juan Wang, Zi-Li Lei, Yan-Hong Yang
Article Number: 195
Published online on: 20 May 2026

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Article Open Access

Endothelial NOX4‑driven oxidative stress inhibition reverses HtrA1 deficiency‑induced blood‑brain barrier disruption and cognitive impairment

Shi-Na Song, Jun-Ying Wu, Mao-Mei Song, Xiao-Feng Li, Jian-Ming Wang, Wen-Hui Jia, Chang-Xin Li, Sui-Yi Xu
Article Number: 194
Published online on: 19 May 2026

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Review Open Access

Bone‑origin repair in diabetic foot ulcers: Mechanisms of callus formation and endocrine effects in healing (Review)

Sen Chen, Xiaofei Cui
Article Number: 193
Published online on: 19 May 2026

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Review Open Access

Unraveling the molecular landscape of chronic radiation injury: From oxidative stress signaling to translational modeling (Review)

Zhenjun Xi, Xiaodong Li, Chunhui Yang, Li Wang, Jingxin Mao, Qianqian Liu, Chang Liu, Qian Li, Yuanfang Hou, Jie Wan, Chengzhuo Yang, Feiji Sun, Chao Yu, Miao Wang, Baocheng Yuan, Yongsheng Liu, Qing Hu, Li Zhang, Xuemei Li, Xiaobing Li
Article Number: 192
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Cocktail therapy with a combination of interferon, ribavirin and angiotensin‑II type 1 receptor blocker attenuates murine liver fibrosis development

Hitoshi Yoshiji, Ryuichi Noguchi, Yasuhide Ikenaka, Kosuke Kaji, Yosuke Aihara, Yusaku Shirai, Junichi Yoshii, Koji Yanase, Hiroshi Fukui
Article Number: 191
Published online on: 18 May 2026

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Review Open Access

Autophagy and metabolic homeostasis: Exploration in obesity‑related metabolic diseases (Review)

Chenglin Lu, Xiangyu Qi, Yuting Tong, Peng Lu, Dandan Luo, Qingbo Guan, Chunxiao Yu
Article Number: 190
Published online on: 14 May 2026

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Review Open Access

Primary cilia dysfunction: A critical driver of metabolic diseases (Review)

Xiaojing Wang, Yi Jin, Kejia Xie, Pengfei Yao, Liguo Song, Hongdan Liu, Yanjie Tan
Article Number: 189
Published online on: 14 May 2026

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Review Open Access

Gut‑brain axis in anesthesia and critical illness: Molecular crosstalk and its impact on delirium and outcome (Review)

Xigang Ma, Yongsen Zhao
Article Number: 188
Published online on: 14 May 2026

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Article Open Access

Betulinic acid alleviates the inflammatory injury of osteoblasts in osteoporosis by augmenting autophagy via the AMPK-mTOR signaling pathway

Yiwei Zhao, Zechao Qu, Lin Liu, Yong Zhang, Xiaohao Wang, Bo Zhang, Yining Gong, Liang Yan
Article Number: 187
Published online on: 13 May 2026

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Correction Open Access

[Corrigendum] Induction of cardiomyocyte‑like cells from hair follicle cells in mice

Yong-Hee Kim, Bang-Jin Kim, Seok-Man Kim, Sun-Uk Kim, Buom-Yong Ryu
Article Number: 186
Published online on: 13 May 2026

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Review Open Access

Spatial hepatology: Decoding liver zonation for metabolic and regenerative therapeutics (Review)

Guiqing Chen, Hongyan Jia, Kai Zhao, Chang Gao, Yue Liu, Hong Zhu, Dakai Yang, Yun Cai
Article Number: 185
Published online on: 13 May 2026

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Hepatic p38γ exacerbates acetaminophen‑induced acute liver injury via PI3K/Akt‑dependent mechanisms

Hui Fang, Min Shu, Jiaju Wang, Heng Tian, Jianguo Zhang, Ying Hu, He Li, Huan Zhou, Kangsheng Gu, Zhenhua Ren
Article Number: 184
Published online on: 12 May 2026

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Pharmacological activity, molecular mechanisms and therapeutic potential of erianin (Review)

Chengyi Ming, Ni Zhu, You Yu, Hong Zhou, Meichun Hu
Article Number: 183
Published online on: 12 May 2026

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Rab27: Molecular switch of tumor exosome secretion (Review)

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Article Number: 182
Published online on: 12 May 2026

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IL‑17A+ γδT cell activation via the HMGB1‑TLR2/4‑NF‑κB signaling pathways in biliary atresia

Meng-Xin Zhang, Jing-Feng Tang, Mei Hong, Ying Yang, Yun Zhou, Shui-Qing Chi, Li-Ying Rong, Guo-Qing Cao, Xi Zhang, Jin-Xiang Zhang, Shao-Tao Tang
Article Number: 181
Published online on: 11 May 2026

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CircRAD18 promotes glioblastoma proliferation, migration and invasion via the miR‑1231/LUC7L2 axis

Lumeng Song, Ping Xiong, Amu Jike, Xiaochao Xia, Lifang Mao, Zihao Wang, Yinchuan Cheng, Shumin Wang, Shizheng Tan, Dongnan Yu, Zheng Li, Xiaoping Tang, Shun Li
Article Number: 180
Published online on: 11 May 2026

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[Corrigendum] Expression of FKBP52 in the ovaries of PCOS rats

Shiyan Song, Yong Tan
Article Number: 179
Published online on: 11 May 2026

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miR‑223‑3p promotes microglial lactylation and M1 polarization via the FBXW7/Notch1/Hes1/SIRT1 axis

Xiaoyu Wang, Lin Song, Jiafeng Wang, Qianqian Xie, Yan Wang, Chunyan Li, Tianqi Wang, Yifeng Du
Article Number: 178
Published online on: 08 May 2026

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Radiotherapy and cytokines: A systems view of immunotherapy and toxicity (Review)

Siyuan Zhou, Yurong Jiang, Jixu Fan, Minjie Guo, Yi Wen, Chunhua Dai
Article Number: 177
Published online on: 08 May 2026

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Advances in understanding the NLRP3 inflammasome‑mediated mechanisms and therapeutic targets in diabetic nephropathy (Review)

Xiwei Wang, Shuang Li, Xiaotian Ge, Tao Xie, Sainan Li, Ruiqi Yuan, Tianxi Li, Hui Yuan
Article Number: 176
Published online on: 06 May 2026

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Expression of Concern Open Access

[Expression of Concern] ISL1 promotes cancer progression and inhibits cisplatin sensitivity in triple‑negative breast cancer cells

Yang Zhang, Lu Wang, Peng Gao, Zhiguo Sun, Ning Li, Yanqin Lu, Jianglun Shen, Jian Sun, Yiming Yang, Hao Dai, Haifeng Cai
Article Number: 175
Published online on: 06 May 2026

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Phosphorylation beyond the plasma membrane: How secretory pathway kinases sculpt the cellular dialogue in cancer (Review)

Ziang Geng, Shu Guan, Shaoqi Du, Shuo Zhang, Jiaxin Hao, Siyuan Tian, Chen Zhu, Shaonan Du
Article Number: 174
Published online on: 06 May 2026

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Ferroptosis in musculoskeletal disorders: Emerging mechanisms and therapeutic opportunities (Review)

Wenhui Gu, Haifeng Zhang, Lisha Ye, Fangming Liu, Ting Xu, Yinxian Yu, Guohua Wang
Article Number: 173
Published online on: 05 May 2026

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Retraction Open Access

[Retracted] Regulation of p38 MAPK phosphorylation inhibits chondrocyte apoptosis in response to heat stress or mechanical stress

Ken Takebe, Takayuki Nishiyama, Shinya Hayashi, Shingo Hashimoto, Takaaki Fujishiro, Noriyuki Kanzaki, Kohei Kawakita, Kenjiro Iwasa, Ryosuke Kuroda, Masahiro Kurosaka
Article Number: 172
Published online on: 04 May 2026

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Dapagliflozin attenuates ferroptosis in diabetic nephropathy through activation of the Nrf2/HO‑1 signaling pathway

Hanshuang Liu, Xiaoxiao Zhang, Yubing Cui, Shengxi Xiong, Linjuan Huang, Min Li, Chen Shao, Xiaolei Hu
Article Number: 171
Published online on: 30 April 2026

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Ligustroflavone protects against acute kidney injury by inhibiting ferroptosis via acting on GSK3β/NRF2 signaling

Jiayu Song, Long Wang, Yaru Wang, Jie Meng, Jingyi Sheng, Yongfeng Zhao, San Yan Xu, Juan Lei, Fangfang Cai, Yunwen Yang
Article Number: 170
Published online on: 30 April 2026

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[Corrigendum] Differential regulation of the biosynthesis of glucose transporters by the PI3‑K and MAPK pathways of insulin signaling by treatment with novel compounds from Liriope platyphylla

Yoen Kyung Lee, Ji Eun Kim, So Hee Nam, Jun Seo Goo, Sun Il Cho, Young Hwan Choi, Chang Jun Bae, Ong Min Woo, Jung Sik Cho, Dae Youn Hwang
Article Number: 169
Published online on: 28 April 2026

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August-2026 Volume 58 Issue 2

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Impact Factor: 5.8

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Moderate downregulation of NDUFA13 promotes cardiomyocytes proliferation and heart regeneration through the glycolysis/c‑Myc/Ccnd1 axis

Ying Gao, Ningjing Qian, Junyan Jin, Jiayi Liu, Bingqi Wang, Yaping Wang
Article Number: 219
Published online on: 12 June 2026

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[Corrigendum] (‑)‑Epigallocatechin‑3‑gallate attenuates myocardial injury induced by ischemia/reperfusion in diabetic rats and in H9c2 cells under hyperglycemic conditions

Yang Wu, Zhong-Yuan Xia, Bo Zhao, Yan Leng, Juan Dou, Qing-Tao Meng, Shao-Qing Lei, Zhi-Ze Chen, Jie Zhu
Article Number: 218
Published online on: 10 June 2026

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Melatonin ameliorates circadian rhythm disruption induced erectile dysfunction by inhibiting oxidative stress mediated pyroptosis via Nrf2/HO‑1 axis

Qingtao Yang, Wei Li, Qi Yu, Jiang Shi, Lu Yang, Jun Qiao, Xi Wei, Changshi Gu, Fa Sun, Tao Li
Article Number: 217
Published online on: 09 June 2026

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Spatial architecture of immunometabolism: Mitochondrial‑organelle interfaces in immune signaling (Review)

Yaping Wu, Hao Yu, Ling Xia, Li Yang, Yu Zhou, Qian Yu
Article Number: 216
Published online on: 08 June 2026

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Urea cycle dysregulation and arginine pathways in the pathogenesis of NAFLD and NASH (Review)

Boying Zhu, Chaoyang Wang, Peng Liu, Zhifeng Qu, Ran Qi, Shengjiang Chen, Huanzhang Niu
Article Number: 215
Published online on: 08 June 2026

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Withaferin A, a candidate drug for lupus nephritis, confers renal protection via Pon1‑mediated attenuation of oxidative stress

Miao Xue, Junshuai Feng, Xiaorong Mao
Article Number: 214
Published online on: 08 June 2026

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Retraction Open Access

[Retracted] Classical dendritic cells regulate acute lung inflammation and injury in mice with lipopolysaccharide‑induced acute respiratory distress syndrome

Lang Li, Liang Dong, Dan Zhao, Fei Gao, Jie Yan
Article Number: 213
Published online on: 08 June 2026

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Plant‑derived natural products alleviate dexamethasone‑induced skeletal muscle atrophy by modulating FoxO (Review)

Wei Dai, Jiabin Wu, Xiaotong Ma, Mingyu Wu, Ke Li, Haoyang Gao, Wenhong Wang, Weihua Xiao
Article Number: 212
Published online on: 05 June 2026

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Functional hydrogels in cardiovascular therapy: Design, applications and clinical challenges (Review)

Zheming Yang, Jiayin Li, Lingxiao Zhao, Dali Zhang, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 211
Published online on: 04 June 2026

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Experimental rodent models of cardiorenal syndrome types 3 and 4: Insights and clinical relevance (Review)

Stefanny M. Figueroa, Siyi Huang, Javier Reyes‑Osorio, Jean-Jacques Boffa, Cristián A. Amador, Christos E. Chadjichristos, Louis Boutin
Article Number: 210
Published online on: 04 June 2026

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Expression of Concern Open Access

[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia‑induced injury in H9c2  cardiac myocytes

Zhanli Yang, Chuntao Yang, Liangcan Xiao, Xinxue Liao, Aiping Lan, Xiuyu Wang, Ruixian Guo, Peixi Chen, Chengheng Hu, Jianqiang Feng
Article Number: 209
Published online on: 03 June 2026

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Microbiota‑derived indole‑3‑propionic acid reprograms bone marrow stem cell fate via PPARγ suppression to rescue osteoporosis

Jinwu Bai, Ruideng Wang, Jixing Fan, Shilong Su, Gao Si, Qinyong You, Ao Sun, Daole Hu, Shan Gao, Yang Lv, Fang Zhou
Article Number: 208
Published online on: 03 June 2026

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Lactate regulates osteoclastogenesis via H3k18la in osteoarthritis

Zhibo Fan, Qiyue Fu, Tao Sun, Yutong Zhong, Yuefan Ma, Jingwei Jian, Shuosheng Yuan, Shenghong Li, Xiaomei Xu
Article Number: 207
Published online on: 02 June 2026

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Retraction Open Access

[Retracted] miR‑215 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancert

Xiaoxu Gao, Yan Cai, Ruifang An
Article Number: 206
Published online on: 02 June 2026

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Multi‑scale experimental models for the study of angiogenesis (Review)

Qin Yu, Jiarui Hu, Shuangshuang Yuan, Jiexia Gan, Mao Luo, Jianbo Wu, Liqun Wang
Article Number: 205
Published online on: 28 May 2026

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Targeting lactylation in hepatocellular carcinoma: Mechanistic insights and therapeutic opportunities (Review)

Lianting Chen, Feiqiong Gao, Qianru Mei, Yujie Li, Qun Cai, Xudong Feng
Article Number: 204
Published online on: 28 May 2026

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Oxygen‑sensing histone demethylase KDM6A modulates chondrocyte‑to‑osteoblast transdifferentiation by activating the Wnt/β‑catenin pathway

Yi Rong, Hao Yu, Heng Yin, Shaoshuo Li, Jianwei Wang, Zhongyuan Shen, Xinxin Ding, Fanchen Bu, Tianyi Dai, Gean Wu, Zhen Hua
Article Number: 203
Published online on: 28 May 2026

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