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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2013 Volume 42 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

H. pylori infection and gastric cancer: State of the art (Review)

Vincenza Conteduca, Domenico Sansonno, Gianfranco Lauletta, Sabino Russi, Giuseppe Ingravallo, Franco Dammacco
Pages: 5-18
Published online on: 15 November 2012

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Review

Signaling pathways in follicular cell-derived thyroid carcinomas (Review)

Mírian Romitti, Lucieli Ceolin, Débora Rodrigues Siqueira, Carla Vaz Ferreira, Simone Magagnin Wajner, Ana Luiza Maia
Pages: 19-28
Published online on: 29 October 2012

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Review

Defective DNA repair systems and the development of breast and prostate cancer (Review)

Yasuko Kitagishi, Mayumi Kobayashi, Satoru Matsuda
Pages: 29-34
Published online on: 14 November 2012

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Article Open Access

Potent activity of the Hsp90 inhibitor ganetespib in prostate cancer cells irrespective of androgen receptor status or variant receptor expression

Suqin He, Chaohua Zhang, Ayesha A. Shafi, Manuel Sequeira, Jaime Acquaviva, Julie C. Friedland, Jim Sang, Donald L. Smith, Nancy L. Weigel, Yumiko Wada, David A. Proia
Pages: 35-43
Published online on: 14 November 2012

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Article Open Access

Expression of pyruvate dehydrogenase kinase-1 in gastric cancer as a potential therapeutic target

Hoon Hur, Yi Xuan, Young Bae Kim, Gwang Lee, Wooyoung Shim, Jisoo Yun, In-Hye Ham, Sang-Uk Han
Pages: 44-54
Published online on: 06 November 2012

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Article Open Access

Ascorbate supplementation inhibits growth and metastasis of B16FO melanoma and 4T1 breast cancer cells in vitamin C-deficient mice

John Cha, M. Waheed Roomi, Vadim Ivanov, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath
Pages: 55-64
Published online on: 21 November 2012

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Article Open Access

Identification of a mimotope for circulating anti-cytokeratin 8/18 antibody and its usage for the diagnosis of breast cancer

Chang-Kyu Heo, Hai-Min Hwang, Ah Ruem, Dae-Yeul Yu, Ju Yeon Lee, Jong Shin Yoo, In Gyu Kim, Hyang Sook Yoo, Sejeong Oh, Jeong Heon Ko, Eun-Wie Cho
Pages: 65-74
Published online on: 26 October 2012

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Article Open Access

γ-tocotrienol enhances the chemosensitivity of human oral cancer cells to docetaxel through the downregulation of the expression of NF-κB-regulated anti-apoptotic gene products

Kouichi Kani, Yukihiro Momota, Michito Harada, Yoshiko Yamamura, Keiko  Aota, Tomoko Yamanoi, Hideyuki Takano, Katsumi Motegi, Masayuki Azuma
Pages: 75-82
Published online on: 08 November 2012

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Article Open Access

A small-molecule RGD-integrin antagonist inhibits cell adhesion, cell migration and induces anoikis in glioblastoma cells

Marika A. Russo, Mayra Paolillo, Yuly Sanchez-Hernandez, Daniela Curti, Emilio Ciusani, Massimo Serra, Lino Colombo, Sergio Schinelli
Pages: 83-92
Published online on: 20 November 2012

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Article Open Access

Autoantibodies against insulin-like growth factor‑binding protein-2 as a serological biomarker in the diagnosis of lung cancer

Ying Zhang, Xia Ying, Suxia Han, Jing Wang, Xia Zhou, E Bai, Jianying Zhang, Qing Zhu
Pages: 93-100
Published online on: 15 November 2012

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Article

Sorafenib and TRAIL have synergistic effect on hepatocellular carcinoma

Keiichiro Nojiri, Kazushi Sugimoto, Katsuya Shiraki, Masahiko Tameda, Yuuji Inagaki, Suguru Ogura, Chika Kasai, Satoko Kusagawa, Misao Yoneda, Norihiko Yamamoto, Yoshiyuki Takei, Tsutomu Nobori, Masaaki Ito
Pages: 101-108
Published online on: 24 October 2012

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Article

Early salvage radiation therapy combined with short-term hormonal therapy in recurrent prostate cancer after radical prostatectomy: Single-institution 4-year data on outcome, toxicity, health-related quality of life and co-morbidities from 184 consecutive patients treated with 70 Gy

Jeff R. Cortés-González, Enrique Castellanos, Katinka Sandberg, Marie-Hjelm Eriksson, Peter Wiklund, Stefan Carlsson, Gabriella Cohn-Cedermark, Ulrika Harmenberg, Ove Gustafsson, Seymour H. Levitt, Bo Lennernäs, Yvonne Brandberg, Marcela Márquez, Karl-Mikael Kälkner, Sten Nilsson
Pages: 109-117
Published online on: 13 November 2012

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Article Open Access

Protein kinase B/AKT isoform 2 drives migration of human mesenchymal stem cells

Zrinka Bulj, Serena Duchi, Alessandro Bevilacqua, Alessandro Gherardi, Barbara Dozza, Filippo Piccinini, Giulia Adalgisa Mariani, Enrico Lucarelli, Sandro Giannini, Davide Donati, Sandra Marmiroli
Pages: 118-126
Published online on: 15 November 2012

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Article Open Access

DNA methylation of the p14ARF, RASSF1A and APC1A genes as an independent prognostic factor in colorectal cancer patients

Torbjörn K. Nilsson, Zarah M. Löf-Öhlin, Xiao-Feng Sun
Pages: 127-133
Published online on: 30 October 2012

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Article Open Access

Epithelial-mesenchymal transition-related gene expression as a new prognostic marker for neuroblastoma

Megumi Nozato, Setsuko Kaneko, Akira Nakagawara, Hiroaki Komuro
Pages: 134-140
Published online on: 06 November 2012

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Article

High prevalence of epigenetic inactivation of the human four and a half LIM domains 1 gene in human oral cancer

Kazuyuki Koike, Atsushi Kasamatsu, Manabu Iyoda, Yasuhiro Saito, Yukinao Kouzu, Hirofumi Koike, Yosuke Sakamoto, Katsunori Ogawara, Hideki Tanzawa, Katsuhiro Uzawa
Pages: 141-150
Published online on: 24 October 2012

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Article

Effect of transcatheter arterial chemoembolization prior to surgical resection for hepatocellular carcinoma

Hiroki Nishikawa, Akira Arimoto, Tomoko Wakasa, Ryuichi Kita, Toru Kimura, Yukio Osaki
Pages: 151-160
Published online on: 21 November 2012

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Article

SSEA-3 as a novel amplifying cancer cell surface marker in colorectal cancers

Yozo Suzuki, Naotsugu Haraguchi, Hidekazu Takahashi, Mamoru Uemura, Junichi Nishimura, Taishi Hata, Ichiro Takemasa, Tsunekazu Mizushima, Hideshi Ishii, Yuichiro Doki, Masaki Mori, Hirofumi Yamamoto
Pages: 161-167
Published online on: 22 November 2012

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Article

Design, synthesis and preclinical evaluation of NRC-AN-019

Kompella Amala, A. K.S. Bhujanga Rao, Bharathi Gorantla, Christopher S. Gondi, Jasti S. Rao
Pages: 168-178
Published online on: 14 November 2012

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Article

The anticancer agent YC-1 suppresses progestin-stimulated VEGF in breast cancer cells and arrests breast tumor development

Candace E. Carroll, Yayun Liang, Indira Benakanakere, Cynthia Besch-Williford, Salman M. Hyder
Pages: 179-187
Published online on: 24 October 2012

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Article

The secreted protein acidic and rich in cysteine (SPARC) induces endoplasmic reticulum stress leading to autophagy-mediated apoptosis in neuroblastoma

G. S. Sailaja, Praveen Bhoopathi, Bharathi Gorantla, Chandramu Chetty, Venkateswara Rao Gogineni, Kiran Kumar Velpula, Christopher S. Gondi, Jasti S. Rao
Pages: 188-196
Published online on: 24 October 2012

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Article

Distinct expression of C4.4A in colorectal cancer detected by different antibodies Corrigendum in /10.3892/ijo.2016.3694

Hirofumi Yamamoto, Ryota Oshiro, Masahisa Ohtsuka, Mamoru Uemura, Naotsugu Haraguchi, Junichi Nishimura, Ichiro Takemasa, Tsunekazu Mizushima, Yuichiro Doki, Masaki Mori
Pages: 197-201
Published online on: 22 November 2012

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Article

Ethyl acetate extraction from a Chinese herbal formula, Jiedu Xiaozheng Yin, inhibits the proliferation of hepatocellular carcinoma cells via induction of G0/G1 phase arrest in vivo and in vitro

Zhiyun Cao, Wei Lin, Zhengrong Huang, Xuzheng Chen, Jinyan Zhao, Liangpu Zheng, Hongzhi Ye, Zhizhen Liu, Lianming Liao, Jian Du
Pages: 202-210
Published online on: 16 November 2012

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Article

N-acetylcysteine potentiates doxorubicin-induced ATM and p53 activation in ovarian cancer cells

Gabriella Brum, Thomas Carbone, Eric Still, Vendita Correia, Kevin Szulak, David Calianese, Charles Best, Garret Cammarata, Katelyn Higgins, Fang Ji, Wen Di, Yinsheng Wan
Pages: 211-218
Published online on: 26 October 2012

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Article

MiR-21 regulates biological behavior through the PTEN/PI-3 K/Akt signaling pathway in human colorectal cancer cells

Binghong Xiong, Yong Cheng, Li Ma, Caiquan Zhang
Pages: 219-228
Published online on: 20 November 2012

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Article

Sinomenine hydrochloride inhibits human hepatocellular carcinoma cell growth in vitro and in vivo: involvement of cell cycle arrest and apoptosis induction

Xin-Lan Lu, Jin Zeng, Yu-Le Chen, Peng-Mei He, Mai-Xia Wen, Mu-Dan Ren, Ya-Nan Hu, Gui-Fang Lu, Shui-Χiang He
Pages: 229-238
Published online on: 16 November 2012

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Article

The microtubule targeting agent PBOX-15 inhibits integrin-mediated cell adhesion and induces apoptosis in acute lymphoblastic leukaemia cells

Joanne Lysaght, Navin K. Verma, Elaina N. Maginn, Jacqueline M. Ryan, Giuseppe Campiani, Daniela M. Zisterer, D. Clive Williams, Paul V. Browne, Mark P. Lawler, Anthony M. McElligott
Pages: 239-246
Published online on: 06 November 2012

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Article

Expression of LRIG1 and LRIG3 correlates with human papillomavirus status and patient survival in cervical adenocarcinoma

Susanne Muller, David Lindquist, Lena Kanter, Carmen Flores-Staino, Roger Henriksson, Håkan Hedman, Sonia Andersson
Pages: 247-252
Published online on: 16 November 2012

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Article

Asymmetric siRNA targeting the bcl‑2 gene inhibits the proliferation of cancer cells in vitro and in vivo

Yan Yin, Xu Chen, Chang‑Dong Zhang, Pei‑Feng Liu, You‑Rong Duan, Yan‑Rong Fan, Zhi‑Wei Wu, Geng‑Feng Fu, Jian‑Jun Wang, Gen‑Xing Xu
Pages: 253-260
Published online on: 07 November 2012

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Article

Bmi1 knockdown inhibits hepatocarcinogenesis

Zhi-Ping Ruan, Rui Xu, Yi Lv, Tao Tian, Wen-Juan Wang, Hui Guo, Ke-Jun Nan
Pages: 261-268
Published online on: 09 November 2012

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Article

Bcl-3 suppresses Tax-induced NF-κB activation through p65 nuclear translocation blockage in HTLV-1-infected cells

Jinheng Wang, Junying Li, Yanmei Huang, Xiangfeng Song, Zhiguo Niu, Zhitao Gao, Hui Wang
Pages: 269-276
Published online on: 06 November 2012

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Article

Bufalin prevents the migration and invasion of T24 bladder carcinoma cells through the inactivation of matrix metalloproteinases and modulation of tight junctions

Su Hyun Hong, Gi-Young Kim, Young-Chae Chang, Sung-Kwon Moon, Wun-Jae Kim, Yung Hyun Choi
Pages: 277-286
Published online on: 02 November 2012

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Article

Surfactin suppresses TPA-induced breast cancer cell invasion through the inhibition of MMP-9 expression

Sun Young Park, Ji-Hee Kim, Young Ji Lee, Sang Joon Lee, Younghee Kim
Pages: 287-296
Published online on: 13 November 2012

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Article

Microtubule inhibition causes epidermal growth factor receptor inactivation in oesophageal cancer cells

Xuping Wu, Linda Sooman, Johan Lennartsson, Stefan Bergström, Michael Bergqvist, Joachim Gullbo, Simon Ekman
Pages: 297-304
Published online on: 20 November 2012

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Article

Differential expression of IGF-1 mRNA isoforms in colorectal carcinoma and normal colon tissue

Aldona Kasprzak, Witold Szaflarski, Jacek Szmeja, Małgorzata  Andrzejewska, Wiesława Przybyszewska, Elżbieta Kaczmarek, Maria Koczorowska, Tomasz Kościński, Maciej Zabel, Michał Drews
Pages: 305-316
Published online on: 19 November 2012

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Article

Suppression of metastasis of intravenously-inoculated B16/F10 melanoma cells by the novel ginseng-derived ingredient, gintonin: Involvement of autotaxin inhibition

Sung Hee Hwang, Byung-Hwan Lee, Hyeon-Joong Kim, Hee-Jung Cho, Ho-Chul Shin, Keum-Soon Im, Sun-Hye Choi, Tae-Joon Shin, Sang-Mok Lee, Suk Woo Nam, Hyoung-Chun Kim, Hyewon Rhim, Seung-Yeol Nah
Pages: 317-326
Published online on: 20 November 2012

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Article

Differential effects of estrogen receptor ligands on regulation of dihydrotestosterone-induced cell proliferation in endothelial and prostate cancer cells

Chunyan Weng, Jingjing Cai, Juan Wen, Hong Yuan, Kan Yang, Julianne Imperato-McGinley, Yuan-Shan Zhu
Pages: 327-337
Published online on: 06 November 2012

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Article

The dichloromethane extract of the ethnomedicinal plant Neurolaena lobata inhibits NPM/ALK expression which is causal for anaplastic large cell lymphomagenesis

Christine Unger, Ruxandra Popescu, Benedikt Giessrigl, Daniela Laimer, Susanne Heider, Mareike Seelinger, Rene Diaz, Bruno Wallnöfer, Gerda Egger, Melanie Hassler, Martin Knöfler, Leila Saleh, Emine Sahin, Michael Grusch, Monika Fritzer-Szekeres, Helmut Dolznig, Richard Frisch, Lukas Kenner, Brigitte Kopp, Georg Krupitza
Pages: 338-348
Published online on: 06 November 2012

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Article

(-)-Epigallocatechin 3-gallate inhibits invasion by inducing the expression of Raf kinase inhibitor protein in AsPC‑1 human pancreatic adenocarcinoma cells through the modulation of histone deacetylase activity

Sung Ok Kim, Mi Ryeo Kim
Pages: 349-358
Published online on: 06 November 2012

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Article

Trichostatin A induces apoptotic cell death of HeLa cells in a Bcl-2 and oxidative stress-dependent manner

Bo Ra You, Woo Hyun Park
Pages: 359-366
Published online on: 19 November 2012

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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