Journal Articles

Open Access

Angiogenesis inhibitor therapies for advanced renal cell carcinoma: Toxicity and treatment patterns in clinical practice from a global medical chart review

William K. Oh, David McDermott, Camillo Porta, Antonin Levy, Reza Elaidi, Florian Scotte, Robert Hawkins, Daniel Castellano, Joaquim Bellmunt, Sun Young Rha, Jong-Mu Sun, Paul Nathan, Bruce A. Feinberg, Jeffrey Scott, Ray McDermott, Jin-Hee Ahn, John Wagstaff, Yen-Hwa Chang, Yen-Chuan Ou, Paul Donnellan, Chao-Yuan Huang, John McCaffrey, Po-Hui Chiang, Cheng-Keng Chuang, Caroline Korves, Maureen P. Neary, Jose R. Diaz, Faisal Mehmud, Mei Sheng Duh

Pages: 5-16 Published online on: 15 November 2013
Open Access

Differential prognosis of metastatic colorectal cancer patients post-progression to first-line triplet chemotherapy plus bevacizumab, FIr-B/FOx, according to second-line treatment and KRAS genotype

Gemma Bruera, Katia Cannita, Aldo Victor Giordano, Roberto Vicentini, Corrado Ficorella, Enrico Ricevuto

Pages: 17-26 Published online on: 15 November 2013
Open Access

In vitro modulation of MMP-2 and MMP-9 in pediatric human sarcoma cell lines by cytokines, inducers and inhibitors

M. W. Roomi, T. Kalinovsky, M. Rath, A. Niedzwiecki

Pages: 27-34 Published online on: 31 October 2013
Open Access

S(+)-ibuprofen destabilizes MYC/MYCN and AKT, increases p53 expression, and induces unfolded protein response and favorable phenotype in neuroblastoma cell lines

Naohiko Ikegaki, Sakeenah L. Hicks, Paul L. Regan, Joshua Jacobs, Amina S. Jumbo, Payton Leonhardt, Eric F. Rappaport, Xao X. Tang

Pages: 35-43 Published online on: 25 October 2013

Downregulation of DENND2D by promoter hypermethylation is associated with early recurrence of hepatocellular carcinoma

Mitsuro Kanda, Shuji Nomoto, Hisaharu Oya, Hideki Takami, Soki Hibino, Mitsuhiro Hishida, Masaya Suenaga, Suguru Yamada, Yoshikuni Inokawa, Yoko Nishikawa, Mikako Asai, Tsutomu Fujii, Hiroyuki Sugimoto, Yasuhiro Kodera

Pages: 44-52 Published online on: 05 November 2013

Serum miR-210 as a potential biomarker of early clear cell renal cell carcinoma

Hideto Iwamoto, Yusuke Kanda, Takehiro Sejima, Mitsuhiko Osaki, Futoshi Okada, Atsushi Takenaka

Pages: 53-58 Published online on: 07 November 2013

Wnt5b promotes the cell motility essential for metastasis of oral squamous cell carcinoma through active Cdc42 and RhoA

Akinori Takeshita, Soichi Iwai, Yoshihiro Morita, Atsuko Niki-Yonekawa, Masakazu Hamada, Yoshiaki Yura

Pages: 59-68 Published online on: 12 November 2013

Cell division cycle-associated protein 1 overexpression is essential for the malignant potential of colorectal cancers

Yu Kobayashi, Atsushi Takano, Yohei Miyagi, Eiju Tsuchiya, Hiromichi Sonoda, Tomoharu Shimizu, Hidetoshi Okabe, Toru Tani, Yoshihide Fujiyama, Yataro Daigo

Pages: 69-77 Published online on: 15 November 2013

Extracellular matrix composition and interstitial pH modulate NHE1-mediated melanoma cell motility

Anne-Kristin Vahle, Britta Domikowsky, Christian Schwöppe, Hermann Krähling, Sabine Mally, Michael Schäfers, Sven Hermann, Victor Shahin, Jörg Haier, Albrecht Schwab, Christian Stock

Pages: 78-90 Published online on: 31 October 2013

Gallic acid induces apoptosis and inhibits cell migration by upregulating miR-518b in SW1353 human chondrosarcoma cells

Wenna Liang, Xihai Li, Yachan Li, Candong Li, Bizheng Gao, Huijuan Gan, Sumin Li, Jianying Shen, Jie Kang, Shanshan Ding, Xuejuan Lin, Linghong Liao

Pages: 91-98 Published online on: 30 October 2013

Expression of major histocompatibility complex class I-related chain A/B (MICA/B) in pancreatic carcinoma

Zilvinas Dambrauskas, Helena Svensson, Meghnad Joshi, Anders Hyltander, Peter Naredi, Britt-Marie Iresjö

Pages: 99-104 Published online on: 31 October 2013

Serum response factor induces epithelial to mesenchymal transition with resistance to sorafenib in hepatocellular carcinoma

Jun Sang Bae, Sang Jae Noh, Kyoung Min Kim, Kyu Yun Jang, Myoung Ja Chung, Dae Gohn Kim, Woo Sung Moon

Pages: 129-136 Published online on: 30 October 2013

Antitumor activity of neurokinin-1 receptor antagonists in MG-63 human osteosarcoma xenografts

Miguel Muñoz, Michael Berger, Marisa Rosso, Ana Gonzalez-Ortega, Andrés Carranza, Rafael Coveñas

Pages: 137-146 Published online on: 05 November 2013

Epigallocatechin-3-gallate prevents tumor cell implantation/growth in an experimental rat bladder tumor model

Jerzy Jankun, Rick W. Keck, Steven H. Selman

Pages: 147-152 Published online on: 13 November 2013

The fate of Krüppel-like factor 9-positive hepatic carcinoma cells may be determined by the programmed cell death protein 5

Da-Zhi Fu, Ying Cheng, Hui He, Hai-Yang Liu, Yong-Feng Liu

Pages: 153-160 Published online on: 24 October 2013

Suppression of SCIN inhibits human prostate cancer cell proliferation and induces G0/G1 phase arrest

Dong Wang, Shu-Qing Sun, Ying-Hao Yu, Wei-Zhen Wu, Shun-Liang Yang, Jian-Ming Tan

Pages: 161-166 Published online on: 08 November 2013

A novel anthracene derivative, MHY412, induces apoptosis in doxorubicin-resistant MCF-7/Adr human breast cancer cells through cell cycle arrest and downregulation of P-glycoprotein expression

Umasankar De, Pusoon Chun, Wahn Soo Choi, Byung Mu Lee, Nam Deuk Kim, Hyung Ryong Moon, Jee H. Jung, Hyung Sik Kim

Pages: 167-176 Published online on: 31 October 2013

The importance of tissue environment surrounding the tumor on the development of cancer cachexia

Fumihiro Chiba, Kuniyasu Soda, Shigeki Yamada, Yuka Tokutake, Shigeru Chohnan, Fumio Konishi, Toshiki Rikiyama

Pages: 177-186 Published online on: 15 November 2013

Honokiol inhibits U87MG human glioblastoma cell invasion through endothelial cells by regulating membrane permeability and the epithelial-mesenchymal transition

Young Nak Joo, So Young Eun, Sang Won Park, Jae Heun Lee, Ki Churl Chang, Hye Jung Kim

Pages: 187-194 Published online on: 15 November 2013

Application of a new technique, spiral tissue microarrays constructed using needle biopsy specimens, to prostate cancer research

Akira Komiya, Tomonori Kato, Takashi Hori, Junya Fukuoka, Kenji Yasuda, Hideki Fuse

Pages: 195-202 Published online on: 13 November 2013

MicroRNA-126 functions as a tumor suppressor in colorectal cancer cells by targeting CXCR4 via the AKT and ERK1/2 signaling pathways

Yaling Liu, Yu Zhou, Xiao Feng, Ping An, Xiaojing Quan, Hao Wang, Shicai Ye, Caiyuan Yu, Yanting He, Hesheng Luo

Pages: 203-210 Published online on: 05 November 2013

Comprehensive genomic analyses of a metastatic colon cancer to the lung by whole exome sequencing and gene expression analysis

Li Tai Fang, Sharon Lee, Helen Choi, Hong Kwan Kim, Gregory Jew, Hio Chung Kang, Lin Chen, David Jablons, Il-Jin Kim

Pages: 211-221 Published online on: 25 October 2013

Proteasome inhibitors and knockdown of SMG1 cause accumulation of Upf1 and Upf2 in human cells

Xia Zhao, Atsushi Nogawa, Tsukasa Matsunaga, Tsutomu Takegami, Hideaki Nakagawa, Yasuhito Ishigaki

Pages: 222-228 Published online on: 25 October 2013

Androgen receptor decreases CMYC and KRAS expression by upregulating let-7a expression in ER-, PR-, AR+ breast cancer

Shuhua Lyu, Qi Yu, Guoguang Ying, Shuling Wang, Yahong Wang, Jing Zhang, Yun Niu

Pages: 229-237 Published online on: 25 October 2013

Curcumin-loaded nanoparticles enhance apoptotic cell death of U2OS human osteosarcoma cells through the Akt-Bad signaling pathway

Shu-Fen Peng, Chao-Ying Lee, Mann-Jen Hour, Shih-Chang Tsai, Daih-Huang Kuo, Fu-An Chen, Po-Chuen Shieh, Jai-Sing Yang

Pages: 238-246 Published online on: 14 November 2013

Overexpression of Mortalin in hepatocellular carcinoma and its relationship with angiogenesis and epithelial to mesenchymal transition

Jing Chen, Wen-Bin Liu, Wei-Dong Jia, Ge-Liang Xu, Jin-Liang Ma, Mei Huang, Yan-Ru Deng, Jian-Sheng Li

Pages: 247-255 Published online on: 01 November 2013

A novel hydroxamic acid derivative, MHY218, induces apoptosis and cell cycle arrest through downregulation of NF-κB in HCT116 human colon cancer cells

Mi Kyeong Kim, Yong Jung Kang, Dong Hwan Kim, Mohammad Akbar Hossain, Jung Yoon Jang, Sun Hwa Lee, Jeong-Hyun Yoon, Pusoon Chun, Hyung Ryong Moon, Hyung Sik Kim, Hae Young Chung, Nam Deuk Kim

Pages: 256-264 Published online on: 01 November 2013

The expression of C-FABP and PPARγ and their prognostic significance in prostate cancer

Farzad S. Forootan, Shiva S. Forootan, Mohammed I. Malki, Danqing Chen, Gandi Li, Ke Lin, Philip S. Rudland, Christopher S. Foster, Youqiang Ke

Pages: 265-275 Published online on: 05 November 2013

Knockdown of Livin inhibits growth and invasion of gastric cancer cells through blockade of the MAPK pathway in vitro and in vivo

J.-M. Ou, B. Ye, M.-K. Qiu, Y.-X. Dai, Q. Dong, J. Shen, P. Dong, X.-F. Wang, Y.-B. Liu, Z.-W. Quan, Z.-W. Fei

Pages: 276-284 Published online on: 12 November 2013

Close correlation between MEK/ERK and Aurora-B signaling pathways in sustaining tumorigenic potential and radioresistance of gynecological cancer cell lines

Francesco Marampon, Giovanni Luca Gravina, Valdimir M. Popov, Luca Scarsella, Claudio Festuccia, Maria Emilia La Verghetta, Silvia Parente, Manuela Cerasani, Gemma Bruera, Corrado Ficorella, Enrico Ricevuto, Vincenzo Tombolini, Ernesto Di Cesare, Bianca Maria Zani

Pages: 285-294 Published online on: 05 November 2013

The paternally imprinted DLK1-GTL2 locus is differentially methylated in embryonal and alveolar rhabdomyosarcomas

Gabriela Schneider, Mark J. Bowser, Dong-Myung Shin, Frederic G. Barr, Mariusz Z. Ratajczak

Pages: 295-300 Published online on: 29 October 2013

PX-12 inhibits the growth of A549 lung cancer cells via G2/M phase arrest and ROS-dependent apoptosis

Bo Ra You, Hye Rim Shin, Woo Hyun Park

Pages: 301-308 Published online on: 29 October 2013

Halofuginone induces the apoptosis of breast cancer cells and inhibits migration via downregulation of matrix metalloproteinase-9

Mei Ling Jin, Sun Young Park, Young Hun Kim, Geuntae Park, Sang Joon Lee

Pages: 309-318 Published online on: 31 October 2013

Female gender may predict response to FOLFIRINOX in patients with unresectable pancreatic cancer: A single institution retrospective review

Florian Hohla, Georg Hopfinger, Franz Romeder, Gabriel Rinnerthaler, Angelika Bezan, Stefan Stättner, Cornelia Hauser-Kronberger, Hanno Ulmer, Richard Greil

Pages: 319-326 Published online on: 15 November 2013

Effect of a bispidinone analog on mitochondria‑mediated apoptosis in HeLa cells

Myeongjin Yi, Paramasivam Parthiban, Jiyoung Hwang, Xin Zhang, Hyunjin Jeong, Dong Ho Park, Dong-Kyoo Kim

Pages: 327-335 Published online on: 01 November 2013

Selenium improves stem cell potency by stimulating the proliferation and active migration of 3T3-L1 preadipocytes

Shin-Hyung Park, Jeong-Hwan Kim, Soo-Wan Nam, Byung-Woo Kim, Gi-Young Kim, Wun-Jae Kim, Yung Hyun Choi

Pages: 336-342 Published online on: 15 November 2013
Journal Cover

Cover Legend PDF

January 2014
Volume 44 Issue 1

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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