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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
2014-January Volume 44 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Angiogenesis inhibitor therapies for advanced renal cell carcinoma: Toxicity and treatment patterns in clinical practice from a global medical chart review

William K. Oh, David McDermott, Camillo Porta, Antonin Levy, Reza Elaidi, Florian Scotte, Robert Hawkins, Daniel Castellano, Joaquim Bellmunt, Sun Young Rha, Jong-Mu Sun, Paul Nathan, Bruce A. Feinberg, Jeffrey Scott, Ray McDermott, Jin-Hee Ahn, John Wagstaff, Yen-Hwa Chang, Yen-Chuan Ou, Paul Donnellan, Chao-Yuan Huang, John McCaffrey, Po-Hui Chiang, Cheng-Keng Chuang, Caroline Korves, Maureen P. Neary, Jose R. Diaz, Faisal Mehmud, Mei Sheng Duh
Pages: 5-16
Published online on: 15 November 2013

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Article Open Access

Differential prognosis of metastatic colorectal cancer patients post-progression to first-line triplet chemotherapy plus bevacizumab, FIr-B/FOx, according to second-line treatment and KRAS genotype

Gemma Bruera, Katia Cannita, Aldo Victor Giordano, Roberto Vicentini, Corrado Ficorella, Enrico Ricevuto
Pages: 17-26
Published online on: 15 November 2013

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Article Open Access

In vitro modulation of MMP-2 and MMP-9 in pediatric human sarcoma cell lines by cytokines, inducers and inhibitors

M. W. Roomi, T. Kalinovsky, M. Rath, A. Niedzwiecki
Pages: 27-34
Published online on: 31 October 2013

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Article Open Access

S(+)-ibuprofen destabilizes MYC/MYCN and AKT, increases p53 expression, and induces unfolded protein response and favorable phenotype in neuroblastoma cell lines

Naohiko Ikegaki, Sakeenah L. Hicks, Paul L. Regan, Joshua Jacobs, Amina S. Jumbo, Payton Leonhardt, Eric F. Rappaport, Xao X. Tang
Pages: 35-43
Published online on: 25 October 2013

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Article

Downregulation of DENND2D by promoter hypermethylation is associated with early recurrence of hepatocellular carcinoma

Mitsuro Kanda, Shuji Nomoto, Hisaharu Oya, Hideki Takami, Soki Hibino, Mitsuhiro Hishida, Masaya Suenaga, Suguru Yamada, Yoshikuni Inokawa, Yoko Nishikawa, Mikako Asai, Tsutomu Fujii, Hiroyuki Sugimoto, Yasuhiro Kodera
Pages: 44-52
Published online on: 05 November 2013

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Article

Serum miR-210 as a potential biomarker of early clear cell renal cell carcinoma

Hideto Iwamoto, Yusuke Kanda, Takehiro Sejima, Mitsuhiko Osaki, Futoshi Okada, Atsushi Takenaka
Pages: 53-58
Published online on: 07 November 2013

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Article

Wnt5b promotes the cell motility essential for metastasis of oral squamous cell carcinoma through active Cdc42 and RhoA

Akinori Takeshita, Soichi Iwai, Yoshihiro Morita, Atsuko Niki-Yonekawa, Masakazu Hamada, Yoshiaki Yura
Pages: 59-68
Published online on: 12 November 2013

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Article

Cell division cycle-associated protein 1 overexpression is essential for the malignant potential of colorectal cancers

Yu Kobayashi, Atsushi Takano, Yohei Miyagi, Eiju Tsuchiya, Hiromichi Sonoda, Tomoharu Shimizu, Hidetoshi Okabe, Toru Tani, Yoshihide Fujiyama, Yataro Daigo
Pages: 69-77
Published online on: 15 November 2013

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Article

Extracellular matrix composition and interstitial pH modulate NHE1-mediated melanoma cell motility

Anne-Kristin Vahle, Britta Domikowsky, Christian Schwöppe, Hermann Krähling, Sabine Mally, Michael Schäfers, Sven Hermann, Victor Shahin, Jörg Haier, Albrecht Schwab, Christian Stock
Pages: 78-90
Published online on: 31 October 2013

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Article

Gallic acid induces apoptosis and inhibits cell migration by upregulating miR-518b in SW1353 human chondrosarcoma cells

Wenna Liang, Xihai Li, Yachan Li, Candong Li, Bizheng Gao, Huijuan Gan, Sumin Li, Jianying Shen, Jie Kang, Shanshan Ding, Xuejuan Lin, Linghong Liao
Pages: 91-98
Published online on: 30 October 2013

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Article

Expression of major histocompatibility complex class I-related chain A/B (MICA/B) in pancreatic carcinoma

Zilvinas Dambrauskas, Helena Svensson, Meghnad Joshi, Anders Hyltander, Peter Naredi, Britt-Marie Iresjö
Pages: 99-104
Published online on: 31 October 2013

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Article

Superior antimitogenic and chemosensitization activities of the combination treatment of the histone deacetylase inhibitor apicidin and proteasome inhibitors on human colorectal cancer cells

Mohamed-Salah I. Abaza, Abdul-Majeed Bahman, Raja'a Al-Attiyah
Pages: 105-128
Published online on: 22 October 2013

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Article

Serum response factor induces epithelial to mesenchymal transition with resistance to sorafenib in hepatocellular carcinoma

Jun Sang Bae, Sang Jae Noh, Kyoung Min Kim, Kyu Yun Jang, Myoung Ja Chung, Dae Gohn Kim, Woo Sung Moon
Pages: 129-136
Published online on: 30 October 2013

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Article

Antitumor activity of neurokinin-1 receptor antagonists in MG-63 human osteosarcoma xenografts

Miguel Muñoz, Michael Berger, Marisa Rosso, Ana Gonzalez-Ortega, Andrés Carranza, Rafael Coveñas
Pages: 137-146
Published online on: 05 November 2013

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Article

Epigallocatechin-3-gallate prevents tumor cell implantation/growth in an experimental rat bladder tumor model

Jerzy Jankun, Rick W. Keck, Steven H. Selman
Pages: 147-152
Published online on: 13 November 2013

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The fate of Krüppel-like factor 9-positive hepatic carcinoma cells may be determined by the programmed cell death protein 5

Da-Zhi Fu, Ying Cheng, Hui He, Hai-Yang Liu, Yong-Feng Liu
Pages: 153-160
Published online on: 24 October 2013

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Article

Suppression of SCIN inhibits human prostate cancer cell proliferation and induces G0/G1 phase arrest

Dong Wang, Shu-Qing Sun, Ying-Hao Yu, Wei-Zhen Wu, Shun-Liang Yang, Jian-Ming Tan
Pages: 161-166
Published online on: 08 November 2013

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Article

A novel anthracene derivative, MHY412, induces apoptosis in doxorubicin-resistant MCF-7/Adr human breast cancer cells through cell cycle arrest and downregulation of P-glycoprotein expression

Umasankar De, Pusoon Chun, Wahn Soo Choi, Byung Mu Lee, Nam Deuk Kim, Hyung Ryong Moon, Jee H. Jung, Hyung Sik Kim
Pages: 167-176
Published online on: 31 October 2013

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Article

The importance of tissue environment surrounding the tumor on the development of cancer cachexia

Fumihiro Chiba, Kuniyasu Soda, Shigeki Yamada, Yuka Tokutake, Shigeru Chohnan, Fumio Konishi, Toshiki Rikiyama
Pages: 177-186
Published online on: 15 November 2013

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Article

Honokiol inhibits U87MG human glioblastoma cell invasion through endothelial cells by regulating membrane permeability and the epithelial-mesenchymal transition

Young Nak Joo, So Young Eun, Sang Won Park, Jae Heun Lee, Ki Churl Chang, Hye Jung Kim
Pages: 187-194
Published online on: 15 November 2013

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Article

Application of a new technique, spiral tissue microarrays constructed using needle biopsy specimens, to prostate cancer research

Akira Komiya, Tomonori Kato, Takashi Hori, Junya Fukuoka, Kenji Yasuda, Hideki Fuse
Pages: 195-202
Published online on: 13 November 2013

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Article

MicroRNA-126 functions as a tumor suppressor in colorectal cancer cells by targeting CXCR4 via the AKT and ERK1/2 signaling pathways

Yaling Liu, Yu Zhou, Xiao Feng, Ping An, Xiaojing Quan, Hao Wang, Shicai Ye, Caiyuan Yu, Yanting He, Hesheng Luo
Pages: 203-210
Published online on: 05 November 2013

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Article

Comprehensive genomic analyses of a metastatic colon cancer to the lung by whole exome sequencing and gene expression analysis

Li Tai Fang, Sharon Lee, Helen Choi, Hong Kwan Kim, Gregory Jew, Hio Chung Kang, Lin Chen, David Jablons, Il-Jin Kim
Pages: 211-221
Published online on: 25 October 2013

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Article

Proteasome inhibitors and knockdown of SMG1 cause accumulation of Upf1 and Upf2 in human cells

Xia Zhao, Atsushi Nogawa, Tsukasa Matsunaga, Tsutomu Takegami, Hideaki Nakagawa, Yasuhito Ishigaki
Pages: 222-228
Published online on: 25 October 2013

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Article

Androgen receptor decreases CMYC and KRAS expression by upregulating let-7a expression in ER-, PR-, AR+ breast cancer

Shuhua Lyu, Qi Yu, Guoguang Ying, Shuling Wang, Yahong Wang, Jing Zhang, Yun Niu
Pages: 229-237
Published online on: 25 October 2013

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Article

Curcumin-loaded nanoparticles enhance apoptotic cell death of U2OS human osteosarcoma cells through the Akt-Bad signaling pathway

Shu-Fen Peng, Chao-Ying Lee, Mann-Jen Hour, Shih-Chang Tsai, Daih-Huang Kuo, Fu-An Chen, Po-Chuen Shieh, Jai-Sing Yang
Pages: 238-246
Published online on: 14 November 2013

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Article

Overexpression of Mortalin in hepatocellular carcinoma and its relationship with angiogenesis and epithelial to mesenchymal transition

Jing Chen, Wen-Bin Liu, Wei-Dong Jia, Ge-Liang Xu, Jin-Liang Ma, Mei Huang, Yan-Ru Deng, Jian-Sheng Li
Pages: 247-255
Published online on: 01 November 2013

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Article

A novel hydroxamic acid derivative, MHY218, induces apoptosis and cell cycle arrest through downregulation of NF-κB in HCT116 human colon cancer cells

Mi Kyeong Kim, Yong Jung Kang, Dong Hwan Kim, Mohammad Akbar Hossain, Jung Yoon Jang, Sun Hwa Lee, Jeong-Hyun Yoon, Pusoon Chun, Hyung Ryong Moon, Hyung Sik Kim, Hae Young Chung, Nam Deuk Kim
Pages: 256-264
Published online on: 01 November 2013

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Article

The expression of C-FABP and PPARγ and their prognostic significance in prostate cancer

Farzad S. Forootan, Shiva S. Forootan, Mohammed I. Malki, Danqing Chen, Gandi Li, Ke Lin, Philip S. Rudland, Christopher S. Foster, Youqiang Ke
Pages: 265-275
Published online on: 05 November 2013

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Article

Knockdown of Livin inhibits growth and invasion of gastric cancer cells through blockade of the MAPK pathway in vitro and in vivo

J.-M. Ou, B. Ye, M.-K. Qiu, Y.-X. Dai, Q. Dong, J. Shen, P. Dong, X.-F. Wang, Y.-B. Liu, Z.-W. Quan, Z.-W. Fei
Pages: 276-284
Published online on: 12 November 2013

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Article

Close correlation between MEK/ERK and Aurora-B signaling pathways in sustaining tumorigenic potential and radioresistance of gynecological cancer cell lines

Francesco Marampon, Giovanni Luca Gravina, Valdimir M. Popov, Luca Scarsella, Claudio Festuccia, Maria Emilia La Verghetta, Silvia Parente, Manuela Cerasani, Gemma Bruera, Corrado Ficorella, Enrico Ricevuto, Vincenzo Tombolini, Ernesto Di Cesare, Bianca Maria Zani
Pages: 285-294
Published online on: 05 November 2013

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Article

The paternally imprinted DLK1-GTL2 locus is differentially methylated in embryonal and alveolar rhabdomyosarcomas

Gabriela Schneider, Mark J. Bowser, Dong-Myung Shin, Frederic G. Barr, Mariusz Z. Ratajczak
Pages: 295-300
Published online on: 29 October 2013

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Article

PX-12 inhibits the growth of A549 lung cancer cells via G2/M phase arrest and ROS-dependent apoptosis

Bo Ra You, Hye Rim Shin, Woo Hyun Park
Pages: 301-308
Published online on: 29 October 2013

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Article

Halofuginone induces the apoptosis of breast cancer cells and inhibits migration via downregulation of matrix metalloproteinase-9 Expression of Concern in /10.3892/ijo.2025.5812

Mei Ling Jin, Sun Young Park, Young Hun Kim, Geuntae Park, Sang Joon Lee
Pages: 309-318
Published online on: 31 October 2013

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Article

Female gender may predict response to FOLFIRINOX in patients with unresectable pancreatic cancer: A single institution retrospective review

Florian Hohla, Georg Hopfinger, Franz Romeder, Gabriel Rinnerthaler, Angelika Bezan, Stefan Stättner, Cornelia Hauser-Kronberger, Hanno Ulmer, Richard Greil
Pages: 319-326
Published online on: 15 November 2013

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Article

Effect of a bispidinone analog on mitochondria‑mediated apoptosis in HeLa cells

Myeongjin Yi, Paramasivam Parthiban, Jiyoung Hwang, Xin Zhang, Hyunjin Jeong, Dong Ho Park, Dong-Kyoo Kim
Pages: 327-335
Published online on: 01 November 2013

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Article

Selenium improves stem cell potency by stimulating the proliferation and active migration of 3T3-L1 preadipocytes

Shin-Hyung Park, Jeong-Hwan Kim, Soo-Wan Nam, Byung-Woo Kim, Gi-Young Kim, Wun-Jae Kim, Yung Hyun Choi
Pages: 336-342
Published online on: 15 November 2013

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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