Journal Articles

Open Access

Death-associated protein kinase: A molecule with functional antagonistic duality and a potential role in inflammatory bowel disease (Review)

Sara Steinmann, Kristina Scheibe, Katharina Erlenbach-Wuensch, Clemens Neufert, Regine Schneider-Stock

Pages: 5-15 Published online on: 11 May 2015

Plasminogen activation system in oral cancer: Relevance in prognosis and therapy (Review)

Marzena Wyganowska-Świątkowska, Jerzy Jankun

Pages: 16-24 Published online on: 22 May 2015

Interactional role of microRNAs and bHLH-PAS proteins in cancer (Review)

Yumin Li, Yucai Wei, Jiwu Guo, Yusheng Cheng, Wenting He

Pages: 25-34 Published online on: 15 May 2015

Function and mechanism of F-box proteins in gastric cancer (Review)

Jian Gong, Juan Cao, Guinan Liu, Ji-Rong Huo

Pages: 43-50 Published online on: 04 May 2015
Open Access

Sulforaphane reduces molecular response to hypoxia in ovarian tumor cells independently of their resistance to chemotherapy

Michal Pastorek, Veronika Simko, Martina Takacova, Monika Barathova, Maria Bartosova, Luba Hunakova, Olga Sedlakova, Sona Hudecova, Olga Krizanova, Franck Dequiedt, Silvia Pastorekova, Jan Sedlak

Pages: 51-60 Published online on: 05 May 2015
Open Access

Establishment of patient-derived cancer xenografts in immunodeficient NOG mice

Tsuyoshi Chijiwa, Kenji Kawai, Akira Noguchi, Hidemitsu Sato, Akimune Hayashi, Haruhiko Cho, Manabu Shiozawa, Takeshi Kishida, Soichiro Morinaga, Tomoyuki Yokose, Makoto Katayama, Nobuo Takenaka, Hiroshi Suemizu, Roppei Yamada, Yoshiyasu Nakamura, Takashi Ohtsu, Yasuo Takano, Kohzoh Imai, Yohei Miyagi, Masato Nakamura

Pages: 61-70 Published online on: 11 May 2015
Open Access

Combined inhibition of MEK and mTOR has a synergic effect on angiosarcoma tumorgrafts

Nicholas J. Andersen, Elissa B. Boguslawski, Cynthia Y. Kuk, Christopher M. Chambers, Nicholas S. Duesbery

Pages: 71-80 Published online on: 06 May 2015
Open Access

Anti-chondroitin sulfate proteoglycan 4-specific antibodies modify the effects of vemurafenib on melanoma cells differentially in normoxia and hypoxia

Daniela Pucciarelli, Nina Lengger, Martina Takacova, Lucia Csaderova, Maria Bartosova, Heimo Breiteneder, Silvia Pastorekova, Christine Hafner

Pages: 81-90 Published online on: 18 May 2015
Open Access

Characterization of glioma stem-like cells from human glioblastomas

Shun Yamamuro, Yutaka Okamoto, Emiko Sano, Yushi Ochiai, Akiyoshi Ogino, Takashi Ohta, Hiroyuki Hara, Takuya Ueda, Tomohiro Nakayama, Atsuo Yoshino, Yoichi Katayama

Pages: 91-96 Published online on: 07 May 2015
Open Access

A novel approach to detect KRAS/BRAF mutation for colon cancer: Highly sensitive simultaneous detection of mutations and simple pre-treatment without DNA extraction

Shun-Ichi Suzuki, Satoshi Matsusaka, Mitsuharu Hirai, Harumi Shibata, Koichi Takagi, Nobuyuki Mizunuma, Kiyohiko Hatake

Pages: 97-105 Published online on: 30 April 2015
Open Access

Leupaxin is expressed in mammary carcinoma and acts as a transcriptional activator of the estrogen receptor α

Silke Kaulfuss, Anna-Maria Herr, Anja Büchner, Bernhard Hemmerlein, Andreas R. Günthert, Peter Burfeind

Pages: 106-114 Published online on: 06 May 2015

Pyrrole-imidazole polyamide-mediated silencing of KCNQ1OT1 expression induces cell death in Wilms' tumor cells

Shinsuke Yoshizawa, Kyoko Fujiwara, Kiminobu Sugito, Shota Uekusa, Hiroyuki Kawashima, Reina Hoshi, Yosuke Watanabe, Takayuki Hirano, Takeshi Furuya, Takayuki Masuko, Takahiro Ueno, Noboru Fukuda, Masayoshi Soma, Toshinori Ozaki, Tsugumichi Koshinaga, Hiroki Nagase

Pages: 115-121 Published online on: 22 May 2015

Dual inhibition of EGFR and MET induces synthetic lethality in triple-negative breast cancer cells through downregulation of ribosomal protein S6

Yong Weon Yi, Kyusic You, Edward Jeong Bae, Sahng-June Kwak, Yeon-Sun Seong, Insoo Bae

Pages: 122-132 Published online on: 04 May 2015

miR-206 inhibits metastasis-relevant traits by degrading MRTF-A in anaplastic thyroid cancer

Wen-Long Zhang, Wei Lv, Suo-Zhu Sun, Xi-Zhao Wu, Jian-Hua Zhang

Pages: 133-142 Published online on: 08 May 2015

Functional protease profiling for laboratory based diagnosis of invasive aspergillosis

Bassel Sabbagh, Victor Costina, Dieter Buchheidt, Mark Reinwald, Michael Neumaier, Peter Findeisen

Pages: 143-150 Published online on: 04 May 2015

Targeting the neurokinin-1 receptor inhibits growth of human colon cancer cells

Agnès Garnier, Jody Vykoukal, Jochen Hubertus, Eckhard Alt, Dietrich von Schweinitz, Roland Kappler, Michael Berger, Matthias Ilmer

Pages: 151-160 Published online on: 21 May 2015

HMGB1 translocation is involved in the transformation of autophagy complexes and promotes chemoresistance in leukaemia

Qian Kong, Lu-Hong Xu, Wei Xu, Jian-Pei Fang, Hong-Gui Xu

Pages: 161-170 Published online on: 04 May 2015

The novel anti-neuroblastoma agent PF403, inhibits proliferation and invasion in vitro and in brain xenografts

Chao Li, Yan Li, Haining Lv, Shaowu Li, Ke Tang, Wanqi Zhou, Shishan Yu, Xiaoguang Chen

Pages: 179-187 Published online on: 29 April 2015

A novel transcript variant of proteasome activator 28γ: Identification and function in oral cancer cells

Xiaoping Xu, Dongjuan Liu, Ning Ji, Taiwen Li, Longjiang Li, Lu Jiang, Jing Li, Ping Zhang, Xin Zeng, Qianming Chen

Pages: 188-194 Published online on: 30 April 2015

Identification and evaluation of metastasis-related proteins, oxysterol binding protein-like 5 and calumenin, in lung tumors

Kazuya Nagano, Sunao Imai, Xiluli Zhao, Takuya Yamashita, Yasuo Yoshioka, Yasuhiro Abe, Yohei Mukai, Haruhiko Kamada, Shinsaku Nakagawa, Yasuo Tsutsumi, Shin-Ichi Tsunoda

Pages: 195-203 Published online on: 11 May 2015

Trends and regional variation in the incidence of head and neck cancers in England: 2002 to 2011

Caroline E. McCarthy, John K. Field, Bijaya P. Rajlawat, Anne E. Field, Michael W. Marcus

Pages: 204-210 Published online on: 07 May 2015

Zoledronic acid enhances antitumor efficacy of liposomal doxorubicin

Yoshiyuki Hattori, Kazuhiko Shibuya, Kaori Kojima, Andang Miatmoko, Kumi Kawano, Kei-Ichi Ozaki, Etsuo Yonemochi

Pages: 211-219 Published online on: 07 May 2015

Berberis libanotica extract targets NF-κB/COX-2, PI3K/Akt and mitochondrial/caspase signalling to induce human erythroleukemia cell apoptosis

Saada Diab, Chloe Fidanzi, David Y. Léger, Lamia Ghezali, Marion Millot, Frédérique Martin, Rania Azar, Fadi Esseily, Antoine Saab, Vincent Sol, Mona Diab-Assaf, Bertrand Liagre

Pages: 220-230 Published online on: 18 May 2015

Fbxw7 regulates hepatocellular carcinoma migration and invasion via Notch1 signaling pathway

Xing Wang, Juan Zhang, Liang Zhou, Wei Sun, Zhi-Gang Zheng, Peng Lu, Yuan Gao, Xi-Sheng Yang, Zhuo-Chao Zhang, Kai-Shan Tao, Ke-Feng Dou

Pages: 231-243 Published online on: 04 May 2015

Acquisition of new tumor cell properties by MSC-derived exosomes

Yuanyuan Yang, Vesna Bucan, Heike Baehre, Juliane von der Ohe, Anna Otte, Ralf Hass

Pages: 244-252 Published online on: 11 May 2015

CD-200 induces apoptosis and inhibits Bcr-Abl signaling in imatinib-resistant chronic myeloid leukemia with T315I mutation

Zhenghuan Fang, Kyung Hee Jung, Hong Hua Yan, Soo Jung Kim, Mi Kwon Son, Marufa Rumman, Hyunseung Lee, Ki Woon Kim, Hye-Dong Yoo, Soon-Sun Hong

Pages: 253-261 Published online on: 11 May 2015

The PARP inhibitor AZD2281 (Olaparib) induces autophagy/mitophagy in BRCA1 and BRCA2 mutant breast cancer cells

Banu Arun, Ugur Akar, Angelica M. Gutierrez-Barrera, Gabriel N. Hortobagyi, Bulent Ozpolat

Pages: 262-268 Published online on: 12 May 2015

The presence of primary cilia in cancer cells does not predict responsiveness to modulation of smoothened activity

Ashley L. Spann, Kun Yuan, Kayla F. Goliwas, Adam D. Steg, Devanshu D. Kaushik, Yeon-Jin Kwon, Andra R. Frost

Pages: 269-279 Published online on: 15 May 2015

NJK14013, a novel synthetic estrogen receptor-α agonist, exhibits estrogen receptor-independent, tumor cell-specific cytotoxicity

Hye-In Kim, Taelim Kim, Ji-Eun Kim, Jun Lee, Jinyuk Heo, Na-Rae Lee, Nam-Jung Kim, Kyung-Soo Inn

Pages: 280-286 Published online on: 12 May 2015

Deregulation of energetic metabolism in the clear cell renal cell carcinoma: A multiple pathway analysis based on microarray profiling

Andrea Soltysova, Jan Breza, Martina Takacova, Jana Feruszova, Sona Hudecova, Barbora Novotna, Eva Rozborilova, Silvia Pastorekova, Ludevit Kadasi, Olga Krizanova

Pages: 287-295 Published online on: 19 May 2015

miR‑365 overexpression promotes cell proliferation and invasion by targeting ADAMTS-1 in breast cancer

Min Li, Lulu Liu, Wenqiao Zang, Yuanyuan Wang, Yuwen Du, Xiaonan Chen, Ping Li, Juan Li, Guoqiang Zhao

Pages: 296-302 Published online on: 20 May 2015

Genetic manipulation of RPS5 gene expression modulates the initiation of commitment of MEL cells to erythroid maturation: Implications in understanding ribosomopathies

Ioannis S. Vizirianakis, Eleni T. Papachristou, Panagiotis Andreadis, Elena Zopounidou, Christina N. Matragkou, Asterios S. Tsiftsoglou

Pages: 303-314 Published online on: 21 May 2015

The tumor-suppressive microRNA-1/133a cluster targets PDE7A and inhibits cancer cell migration and invasion in endometrial cancer

Noriko Yamamoto, Rika Nishikawa, Takeshi Chiyomaru, Yusuke Goto, Ichiro Fukumoto, Hirokazu Usui, Akira Mitsuhashi, Hideki Enokida, Masayuki Nakagawa, Makio Shozu, Naohiko Seki

Pages: 325-334 Published online on: 05 May 2015

Expansion of NK cells from PBMCs using immobilized 4-1BBL and interleukin-21

Xiaomei Li, Chenhui He, Changzhen Liu, Juan Ma, Pan Ma, Honglian Cui, Hua Tao, Bin Gao

Pages: 335-342 Published online on: 14 May 2015

The synergistic effects of DNA-damaging drugs cisplatin and etoposide with a histone deacetylase inhibitor valproate in high-risk neuroblastoma cells

Tomas Groh, Jan Hrabeta, Mohammed Ashraf Khalil, Helena Doktorova, Tomas Eckschlager, Marie Stiborova

Pages: 343-352 Published online on: 11 May 2015

Constitutive expression of IRF-5 in HTLV-1-infected T cells

Chie Ishikawa, Masachika Senba, Betsy J. Barnes, Naoki Mori

Pages: 361-369 Published online on: 22 May 2015

Modulation of uPA, MMPs and their inhibitors by a novel nutrient mixture in human colorectal, pancreatic and hepatic carcinoma cell lines

M. Waheed Roomi, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath

Pages: 370-376 Published online on: 18 May 2015

Intravesical dual PI3K/mTOR complex 1/2 inhibitor NVP-BEZ235 therapy in an orthotopic bladder cancer model

Masashi Matsushima, Eiji Kikuchi, Kazuhiro Matsumoto, Seiya Hattori, Toshikazu Takeda, Takeo Kosaka, Akira Miyajima, Mototsugu Oya

Pages: 377-383 Published online on: 11 May 2015

Integrin β4 and vinculin contained in exosomes are potential markers for progression of prostate cancer associated with taxane-resistance

Kyojiro Kawakami, Yasunori Fujita, Taku Kato, Kosuke Mizutani, Koji Kameyama, Hiroki Tsumoto, Yuri Miura, Takashi Deguchi, Masafumi Ito

Pages: 384-390 Published online on: 18 May 2015

Human mesenchymal stem cells enhance cancer cell proliferation via IL-6 secretion and activation of ERK1/2

Agmal Scherzad, Magdalena Steber, Thomas Gehrke, Kristen Rak, Katrin Froelich, Philipp Schendzielorz, Rudolf Hagen, Norbert Kleinsasser, Stephan Hackenberg

Pages: 391-397 Published online on: 18 May 2015

Establishment and characterization of gemcitabine-resistant human cholangiocarcinoma cell lines with multidrug resistance and enhanced invasiveness

Wareeporn Wattanawongdon, Chariya Hahnvajanawong, Nisana Namwat, Sirimas Kanchanawat, Thidarut Boonmars, Patcharee Jearanaikoon, Chanwit Leelayuwat, Anchalee Techasen, Wunchana Seubwai

Pages: 398-410 Published online on: 22 May 2015
Journal Cover

Cover Legend PDF

July 2015
Volume 47 Issue 1

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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