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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2015 Volume 47 Issue 1

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Death-associated protein kinase: A molecule with functional antagonistic duality and a potential role in inflammatory bowel disease (Review)

Sara Steinmann, Kristina Scheibe, Katharina Erlenbach-Wuensch, Clemens Neufert, Regine Schneider-Stock
Pages: 5-15
Published online on: 11 May 2015

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Review

Plasminogen activation system in oral cancer: Relevance in prognosis and therapy (Review)

Marzena Wyganowska-Świątkowska, Jerzy Jankun
Pages: 16-24
Published online on: 22 May 2015

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Review

Interactional role of microRNAs and bHLH-PAS proteins in cancer (Review)

Yumin Li, Yucai Wei, Jiwu Guo, Yusheng Cheng, Wenting He
Pages: 25-34
Published online on: 15 May 2015

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Review

Retinoids induce cellular senescence in breast cancer cells by RAR-β dependent and independent pathways: Potential clinical implications (Review)

Anne Shilkaitis, Albert Green, Konstantin Christov
Pages: 35-42
Published online on: 18 May 2015

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Review

Function and mechanism of F-box proteins in gastric cancer (Review)

Jian Gong, Juan Cao, Guinan Liu, Ji-Rong Huo
Pages: 43-50
Published online on: 04 May 2015

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Article Open Access

Sulforaphane reduces molecular response to hypoxia in ovarian tumor cells independently of their resistance to chemotherapy

Michal Pastorek, Veronika Simko, Martina Takacova, Monika Barathova, Maria Bartosova, Luba Hunakova, Olga Sedlakova, Sona Hudecova, Olga Krizanova, Franck Dequiedt, Silvia Pastorekova, Jan Sedlak
Pages: 51-60
Published online on: 05 May 2015

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Article Open Access

Establishment of patient-derived cancer xenografts in immunodeficient NOG mice

Tsuyoshi Chijiwa, Kenji Kawai, Akira Noguchi, Hidemitsu Sato, Akimune Hayashi, Haruhiko Cho, Manabu Shiozawa, Takeshi Kishida, Soichiro Morinaga, Tomoyuki Yokose, Makoto Katayama, Nobuo Takenaka, Hiroshi Suemizu, Roppei Yamada, Yoshiyasu Nakamura, Takashi Ohtsu, Yasuo Takano, Kohzoh Imai, Yohei Miyagi, Masato Nakamura
Pages: 61-70
Published online on: 11 May 2015

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Article Open Access

Combined inhibition of MEK and mTOR has a synergic effect on angiosarcoma tumorgrafts

Nicholas J. Andersen, Elissa B. Boguslawski, Cynthia Y. Kuk, Christopher M. Chambers, Nicholas S. Duesbery
Pages: 71-80
Published online on: 06 May 2015

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Article Open Access

Anti-chondroitin sulfate proteoglycan 4-specific antibodies modify the effects of vemurafenib on melanoma cells differentially in normoxia and hypoxia

Daniela Pucciarelli, Nina Lengger, Martina Takacova, Lucia Csaderova, Maria Bartosova, Heimo Breiteneder, Silvia Pastorekova, Christine Hafner
Pages: 81-90
Published online on: 18 May 2015

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Article Open Access

Characterization of glioma stem-like cells from human glioblastomas

Shun Yamamuro, Yutaka Okamoto, Emiko Sano, Yushi Ochiai, Akiyoshi Ogino, Takashi Ohta, Hiroyuki Hara, Takuya Ueda, Tomohiro Nakayama, Atsuo Yoshino, Yoichi Katayama
Pages: 91-96
Published online on: 07 May 2015

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Article Open Access

A novel approach to detect KRAS/BRAF mutation for colon cancer: Highly sensitive simultaneous detection of mutations and simple pre-treatment without DNA extraction

Shun-Ichi Suzuki, Satoshi Matsusaka, Mitsuharu Hirai, Harumi Shibata, Koichi Takagi, Nobuyuki Mizunuma, Kiyohiko Hatake
Pages: 97-105
Published online on: 30 April 2015

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Article Open Access

Leupaxin is expressed in mammary carcinoma and acts as a transcriptional activator of the estrogen receptor α

Silke Kaulfuss, Anna-Maria Herr, Anja Büchner, Bernhard Hemmerlein, Andreas R. Günthert, Peter Burfeind
Pages: 106-114
Published online on: 06 May 2015

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Article

Pyrrole-imidazole polyamide-mediated silencing of KCNQ1OT1 expression induces cell death in Wilms' tumor cells

Shinsuke Yoshizawa, Kyoko Fujiwara, Kiminobu Sugito, Shota Uekusa, Hiroyuki Kawashima, Reina Hoshi, Yosuke Watanabe, Takayuki Hirano, Takeshi Furuya, Takayuki Masuko, Takahiro Ueno, Noboru Fukuda, Masayoshi Soma, Toshinori Ozaki, Tsugumichi Koshinaga, Hiroki Nagase
Pages: 115-121
Published online on: 22 May 2015

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Article

Dual inhibition of EGFR and MET induces synthetic lethality in triple-negative breast cancer cells through downregulation of ribosomal protein S6

Yong Weon Yi, Kyusic You, Edward Jeong Bae, Sahng-June Kwak, Yeon-Sun Seong, Insoo Bae
Pages: 122-132
Published online on: 04 May 2015

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Article

miR-206 inhibits metastasis-relevant traits by degrading MRTF-A in anaplastic thyroid cancer

Wen-Long Zhang, Wei Lv, Suo-Zhu Sun, Xi-Zhao Wu, Jian-Hua Zhang
Pages: 133-142
Published online on: 08 May 2015

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Article

Functional protease profiling for laboratory based diagnosis of invasive aspergillosis

Bassel Sabbagh, Victor Costina, Dieter Buchheidt, Mark Reinwald, Michael Neumaier, Peter Findeisen
Pages: 143-150
Published online on: 04 May 2015

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Article

Targeting the neurokinin-1 receptor inhibits growth of human colon cancer cells

Agnès Garnier, Jody Vykoukal, Jochen Hubertus, Eckhard Alt, Dietrich von Schweinitz, Roland Kappler, Michael Berger, Matthias Ilmer
Pages: 151-160
Published online on: 21 May 2015

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Article

HMGB1 translocation is involved in the transformation of autophagy complexes and promotes chemoresistance in leukaemia

Qian Kong, Lu-Hong Xu, Wei Xu, Jian-Pei Fang, Hong-Gui Xu
Pages: 161-170
Published online on: 04 May 2015

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Article

Additional effects of engineered stem cells expressing a therapeutic gene and interferon-β in a xenograft mouse model of endometrial cancer

Bo-Rim Yi, Seung U. Kim, Kyung-Chul Choi
Pages: 171-178
Published online on: 11 May 2015

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Article

The novel anti-neuroblastoma agent PF403, inhibits proliferation and invasion in vitro and in brain xenografts Corrigendum in /10.3892/ijo.2022.5415

Chao Li, Yan Li, Haining Lv, Shaowu Li, Ke Tang, Wanqi Zhou, Shishan Yu, Xiaoguang Chen
Pages: 179-187
Published online on: 29 April 2015

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Article

A novel transcript variant of proteasome activator 28γ: Identification and function in oral cancer cells

Xiaoping Xu, Dongjuan Liu, Ning Ji, Taiwen Li, Longjiang Li, Lu Jiang, Jing Li, Ping Zhang, Xin Zeng, Qianming Chen
Pages: 188-194
Published online on: 30 April 2015

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Article

Identification and evaluation of metastasis-related proteins, oxysterol binding protein-like 5 and calumenin, in lung tumors

Kazuya Nagano, Sunao Imai, Xiluli Zhao, Takuya Yamashita, Yasuo Yoshioka, Yasuhiro Abe, Yohei Mukai, Haruhiko Kamada, Shinsaku Nakagawa, Yasuo Tsutsumi, Shin-Ichi Tsunoda
Pages: 195-203
Published online on: 11 May 2015

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Article

Trends and regional variation in the incidence of head and neck cancers in England: 2002 to 2011

Caroline E. McCarthy, John K. Field, Bijaya P. Rajlawat, Anne E. Field, Michael W. Marcus
Pages: 204-210
Published online on: 07 May 2015

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Article

Zoledronic acid enhances antitumor efficacy of liposomal doxorubicin

Yoshiyuki Hattori, Kazuhiko Shibuya, Kaori Kojima, Andang Miatmoko, Kumi Kawano, Kei-Ichi Ozaki, Etsuo Yonemochi
Pages: 211-219
Published online on: 07 May 2015

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Article

Berberis libanotica extract targets NF-κB/COX-2, PI3K/Akt and mitochondrial/caspase signalling to induce human erythroleukemia cell apoptosis

Saada Diab, Chloe Fidanzi, David Y. Léger, Lamia Ghezali, Marion Millot, Frédérique Martin, Rania Azar, Fadi Esseily, Antoine Saab, Vincent Sol, Mona Diab-Assaf, Bertrand Liagre
Pages: 220-230
Published online on: 18 May 2015

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Article

Fbxw7 regulates hepatocellular carcinoma migration and invasion via Notch1 signaling pathway Retraction in /10.3892/ijo.2025.5763

Xing Wang, Juan Zhang, Liang Zhou, Wei Sun, Zhi-Gang Zheng, Peng Lu, Yuan Gao, Xi-Sheng Yang, Zhuo-Chao Zhang, Kai-Shan Tao, Ke-Feng Dou
Pages: 231-243
Published online on: 04 May 2015

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Article

Acquisition of new tumor cell properties by MSC-derived exosomes

Yuanyuan Yang, Vesna Bucan, Heike Baehre, Juliane von der Ohe, Anna Otte, Ralf Hass
Pages: 244-252
Published online on: 11 May 2015

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Article

CD-200 induces apoptosis and inhibits Bcr-Abl signaling in imatinib-resistant chronic myeloid leukemia with T315I mutation

Zhenghuan Fang, Kyung Hee Jung, Hong Hua Yan, Soo Jung Kim, Mi Kwon Son, Marufa Rumman, Hyunseung Lee, Ki Woon Kim, Hye-Dong Yoo, Soon-Sun Hong
Pages: 253-261
Published online on: 11 May 2015

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Article

The PARP inhibitor AZD2281 (Olaparib) induces autophagy/mitophagy in BRCA1 and BRCA2 mutant breast cancer cells

Banu Arun, Ugur Akar, Angelica M. Gutierrez-Barrera, Gabriel N. Hortobagyi, Bulent Ozpolat
Pages: 262-268
Published online on: 12 May 2015

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Article

The presence of primary cilia in cancer cells does not predict responsiveness to modulation of smoothened activity

Ashley L. Spann, Kun Yuan, Kayla F. Goliwas, Adam D. Steg, Devanshu D. Kaushik, Yeon-Jin Kwon, Andra R. Frost
Pages: 269-279
Published online on: 15 May 2015

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Article

NJK14013, a novel synthetic estrogen receptor-α agonist, exhibits estrogen receptor-independent, tumor cell-specific cytotoxicity

Hye-In Kim, Taelim Kim, Ji-Eun Kim, Jun Lee, Jinyuk Heo, Na-Rae Lee, Nam-Jung Kim, Kyung-Soo Inn
Pages: 280-286
Published online on: 12 May 2015

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Article

Deregulation of energetic metabolism in the clear cell renal cell carcinoma: A multiple pathway analysis based on microarray profiling

Andrea Soltysova, Jan Breza, Martina Takacova, Jana Feruszova, Sona Hudecova, Barbora Novotna, Eva Rozborilova, Silvia Pastorekova, Ludevit Kadasi, Olga Krizanova
Pages: 287-295
Published online on: 19 May 2015

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Article

miR‑365 overexpression promotes cell proliferation and invasion by targeting ADAMTS-1 in breast cancer

Min Li, Lulu Liu, Wenqiao Zang, Yuanyuan Wang, Yuwen Du, Xiaonan Chen, Ping Li, Juan Li, Guoqiang Zhao
Pages: 296-302
Published online on: 20 May 2015

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Article

Genetic manipulation of RPS5 gene expression modulates the initiation of commitment of MEL cells to erythroid maturation: Implications in understanding ribosomopathies

Ioannis S. Vizirianakis, Eleni T. Papachristou, Panagiotis Andreadis, Elena Zopounidou, Christina N. Matragkou, Asterios S. Tsiftsoglou
Pages: 303-314
Published online on: 21 May 2015

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Article

Combined treatment with tamoxifen and a fusicoccin derivative (ISIR-042) to overcome resistance to therapy and to enhance the antitumor activity of 5-fluorouracil and gemcitabine in pancreatic cancer cells

Takaaki Miyake, Yoshio Honma, Takeshi Urano, Nobuo Kato, Junji Suzumiya
Pages: 315-324
Published online on: 30 April 2015

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Article

The tumor-suppressive microRNA-1/133a cluster targets PDE7A and inhibits cancer cell migration and invasion in endometrial cancer

Noriko Yamamoto, Rika Nishikawa, Takeshi Chiyomaru, Yusuke Goto, Ichiro Fukumoto, Hirokazu Usui, Akira Mitsuhashi, Hideki Enokida, Masayuki Nakagawa, Makio Shozu, Naohiko Seki
Pages: 325-334
Published online on: 05 May 2015

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Article

Expansion of NK cells from PBMCs using immobilized 4-1BBL and interleukin-21

Xiaomei Li, Chenhui He, Changzhen Liu, Juan Ma, Pan Ma, Honglian Cui, Hua Tao, Bin Gao
Pages: 335-342
Published online on: 14 May 2015

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Article

The synergistic effects of DNA-damaging drugs cisplatin and etoposide with a histone deacetylase inhibitor valproate in high-risk neuroblastoma cells

Tomas Groh, Jan Hrabeta, Mohammed Ashraf Khalil, Helena Doktorova, Tomas Eckschlager, Marie Stiborova
Pages: 343-352
Published online on: 11 May 2015

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Article

Metformin targets Axl and Tyro3 receptor tyrosine kinases to inhibit cell proliferation and overcome chemoresistance in ovarian cancer cells

Nam-Yi Kim, Hwa-Young Lee, Chuhee Lee
Pages: 353-360
Published online on: 12 May 2015

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Article

Constitutive expression of IRF-5 in HTLV-1-infected T cells

Chie Ishikawa, Masachika Senba, Betsy J. Barnes, Naoki Mori
Pages: 361-369
Published online on: 22 May 2015

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Article

Modulation of uPA, MMPs and their inhibitors by a novel nutrient mixture in human colorectal, pancreatic and hepatic carcinoma cell lines

M. Waheed Roomi, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath
Pages: 370-376
Published online on: 18 May 2015

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Article

Intravesical dual PI3K/mTOR complex 1/2 inhibitor NVP-BEZ235 therapy in an orthotopic bladder cancer model

Masashi Matsushima, Eiji Kikuchi, Kazuhiro Matsumoto, Seiya Hattori, Toshikazu Takeda, Takeo Kosaka, Akira Miyajima, Mototsugu Oya
Pages: 377-383
Published online on: 11 May 2015

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Article

Integrin β4 and vinculin contained in exosomes are potential markers for progression of prostate cancer associated with taxane-resistance

Kyojiro Kawakami, Yasunori Fujita, Taku Kato, Kosuke Mizutani, Koji Kameyama, Hiroki Tsumoto, Yuri Miura, Takashi Deguchi, Masafumi Ito
Pages: 384-390
Published online on: 18 May 2015

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Article

Human mesenchymal stem cells enhance cancer cell proliferation via IL-6 secretion and activation of ERK1/2

Agmal Scherzad, Magdalena Steber, Thomas Gehrke, Kristen Rak, Katrin Froelich, Philipp Schendzielorz, Rudolf Hagen, Norbert Kleinsasser, Stephan Hackenberg
Pages: 391-397
Published online on: 18 May 2015

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Article

Establishment and characterization of gemcitabine-resistant human cholangiocarcinoma cell lines with multidrug resistance and enhanced invasiveness

Wareeporn Wattanawongdon, Chariya Hahnvajanawong, Nisana Namwat, Sirimas Kanchanawat, Thidarut Boonmars, Patcharee Jearanaikoon, Chanwit Leelayuwat, Anchalee Techasen, Wunchana Seubwai
Pages: 398-410
Published online on: 22 May 2015

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Journal Cover
September-2026 Volume 69 Issue 3

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

The role of deubiquitinating enzymes and their inhibitors in esophageal carcinoma (Review)

Yu Zhao, Chenghai He, Kexin Chen, Nanting Sun, Ruonan He, Guodong Li
Article Number: 108
Published online on: 16 July 2026

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Correction Open Access

[Corrigendum] AHIF promotes glioblastoma progression and radioresistance via exosomes

Xuejun Dai, Keman Liao, Zhijun Zhuang, Binghong Chen, Zhiyi Zhou, Sunhai Zhou, Guoshi Lin, Feifei Zhang, Yingying Lin, Yifeng Miao, Zhiqiang Li, Renhua Huang, Yongming Qiu, Ruisheng Lin
Article Number: 107
Published online on: 15 July 2026

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Article Open Access

Triptonide enhances DNA damage by inhibiting TRIP13‑mediated DNA repair and synergizes with bortezomib to suppress multiple myeloma

Fen He, Junjun Li, Lijun Peng, Hongyan Zhao, Maoyou Lu, Ruixin Gao, Siqi Wang, Yu Chen, Ruihan Tang, Zhengguo Li, Linlin Zhang, Xinyu Zhang, Qianhao Li, Weihui Chen, Jiayu Liu, Cong Luo, Xi Zeng, Jiliang Xia
Article Number: 106
Published online on: 14 July 2026

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Article Open Access

YAP1‑mediated cytoplasmic‑nuclear translocation of SREBP2 promotes colorectal cancer via regulation of cholesterol metabolism

Luhui Zhong, Min Sun, Di Wu, Yulan Zeng, Min Zhou, Rui Gong, Feifei Gu, Kai Zhang, Xiaoyan Hu, Yue Hu
Article Number: 105
Published online on: 13 July 2026

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Review Open Access

Immunoediting and precision biomarkers in prostate cancer: The emerging role of liquid biopsy, immune contexture and HLA genotype (Review)

Constantin N. Baxevanis, Savvas Stokidis, Sotirios P. Fortis, Maria Goulielmaki, Ourania E. Tsitsilonis, Angelos D. Gritzapis
Article Number: 104
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples

Giovanni Luca Gravina, Andrea Mancini, Guido Ranieri, Boris Di Pasquale, Francesco Marampon, Luigi Di Clemente, Enrico Ricevuto, Claudio Festuccia
Article Number: 103
Published online on: 13 July 2026

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Review Open Access

The neural stem cell‑NSCLC axis: Molecular drivers, microenvironment crosstalk and emerging therapies (Review)

Yanling Xu, Hanmei Duan, Peng Lu, Feng Liu
Article Number: 102
Published online on: 10 July 2026

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Review Open Access

TGF‑β1 in cancer: From tumour suppressor to promoter, molecular mechanisms, and precision therapeutic strategies (Review)

Chao Huang
Article Number: 101
Published online on: 10 July 2026

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Article Open Access

T‑box transcription factor 15 regulated by methyltransferase‑like 3‑mediated N6‑methyladenosine modification promotes immune escape and progression of gastric cancer by activating matrix metalloproteinase 14 transcription

Hongsai Hu, Rong He, Minji Liu, Xuli Liu, Qiongjia Ai, Min Chen, Qian Wang, Wenhui Chen, Weiming Qu
Article Number: 100
Published online on: 09 July 2026

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Review Open Access

Glycolysis‑driven immunosuppression in gastric cancer: Metabolic crosstalk between tumor cells and the immune microenvironment (Review)

Bo Zhang, Lihan Shang, Ziyu Kuang, Chaoran Wang, Bingsheng Sun, Fanming Kong
Article Number: 99
Published online on: 09 July 2026

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Review Open Access

New insights into the physiological, pathological and pharmacological roles of voltage‑gated potassium channel Kv10.1 in cancer (Review)

Yuxiao Zhen, Weibo Hu, Shanshan Dong, Bochang Wang, Jian Shen, Leyuan Ding, Lifeng Li, Hailong An, Xuzhao Wang, Yafei Chen
Article Number: 98
Published online on: 09 July 2026

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Retraction Open Access

[Retracted] Glycyrrhetinic acid induces G1‑phase cell cycle arrest in human non‑small cell lung cancer cells through endoplasmic reticulum stress pathway

Jie Zhu, Meijuan Chen, Ning Chen, Aizhen Ma, Chunyan Zhu, Ruolin Zhao, Miao Jiang, Jing Zhou, Lihong Ye, Haian Fu, Xu Zhang
Article Number: 97
Published online on: 06 July 2026

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October-2026 Volume 69 Issue 4

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

The pivotal role of SCD1 in digestive cancers: Bridging lipid metabolic reprogramming and programmed cell death (Review)

Yangxi Fu, Zheng Wang, Lin Liu, Xudong Tang
Article Number: 112
Published online on: 07 August 2026

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Article Open Access

piR‑164552 promotes malignant progression in head and neck squamous cell carcinoma via the RBM4/EIF4E2 signaling axis: Insights from multi‑omics and functional analyses

Shan Yang, Zhen Shang, Shunxian Xia, Hongbo Liu, Yanhan Dong, Xiaomin Wang, Wenhua Xu, Haijun Lu
Article Number: 111
Published online on: 07 August 2026

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Correction Open Access

[Corrigendum] Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines

Nesstor Pilco‑Ferreto, Gloria   M. Calaf
Article Number: 110
Published online on: 20 July 2026

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Article Open Access

Evaluation of Punicalagin as a multi‑targeted therapeutic agent against endometrial cancer

Zeeshan Ahmad Bhutta, Dohee Ahn, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 109
Published online on: 17 July 2026

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