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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February-2019 Volume 54 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

From chemotherapy to biological therapy: A review of novel concepts to reduce the side effects of systemic cancer treatment (Review)

Volker Schirrmacher
Pages: 407-419
Published online on: 10 December 2018

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Review

Full-length osteopontin and its splice variants as modulators of chemoresistance and radioresistance (Review)

Etel R.P. Gimba, Mariana C.M. Brum, Gabriela Nestal De Moraes
Pages: 420-430
Published online on: 06 December 2018

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Article Open Access

Tunicamycin enhances the suppressive effects of cisplatin on lung cancer growth through PTX3 glycosylation via AKT/NF-κB signaling pathway

Bulbul Ahmmed, Muhammad Noman Khan, Muhammad Azhar Nisar, Sylvanus Kampo, Qin Zheng, Yulin Li, Qiu Yan
Pages: 431-442
Published online on: 28 November 2018

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Article Open Access

MicroRNA-30e inhibits adhesion, migration, invasion and cell cycle progression of prostate cancer cells via inhibition of the activation of the MAPK signaling pathway by downregulating CHRM3 Retraction in /10.3892/ijo.2024.5670

Xin-Min Zheng, Peng Zhang, Man-Hua Liu, Ping Chen, Wei-Bing Zhang
Pages: 443-454
Published online on: 26 November 2018

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Article Open Access

SENP2 exerts an anti‑tumor effect on chronic lymphocytic leukemia cells through the inhibition of the Notch and NF‑κB signaling pathways

Xiu‑Li Chen, Shi‑Fen Wang, Xue‑Ting Liang, Hui‑Xin Liang, Ting‑Ting Wang, Shun‑Quan Wu, Zong‑Jian Qiu, Rong Zhan, Zhen‑Shu Xu
Pages: 455-466
Published online on: 14 November 2018

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Article Open Access

Functional role of RBM10 in lung adenocarcinoma proliferation

Xiuna Sun, Mengqi Jia, Wei Sun, Lu Feng, Chundong Gu, Taihua Wu
Pages: 467-478
Published online on: 22 November 2018

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Article Open Access

High PLK4 expression promotes tumor progression and induces epithelial‑mesenchymal transition by regulating the Wnt/β‑catenin signaling pathway in colorectal cancer Corrigendum in /10.3892/ijo.2021.5213 Corrigendum in /10.3892/ijo.2021.5291

Zhibin Liao, Hongwei Zhang, Pan Fan, Qibo Huang, Keshuai Dong, Yongqiang Qi, Jia Song, Lin Chen, Huifang Liang, Xiaoping Chen, Zhanguo Zhang, Bixiang Zhang
Pages: 479-490
Published online on: 10 December 2018

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Article Open Access

High methylation of the 4-aminobutyrate aminotransferase gene predicts a poor prognosis in patients with myelodysplastic syndrome

Guangjie Zhao, Nianyi Li, Shuang Li, Wanling Wu, Xiaoqin Wang, Jingwen Gu
Pages: 491-504
Published online on: 04 December 2018

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Article Open Access

Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation

Laura Antonucci, Laura Di Magno, Davide D'Amico, Simona Manni, Silvia Maria Serrao, Fiorella Di Pastena, Rosa Bordone, Zuleyha Nihan Yurtsever, Miriam Caimano, Marialaura Petroni, Alessandra Giorgi, Maria Eugenia Schininà, John R. Yates III, Lucia Di Marcotullio, Enrico De Smaele, Saula Checquolo, Carlo Capalbo, Enzo Agostinelli, Marella Maroder, Sonia Coni, Gianluca Canettieri
Pages: 505-514
Published online on: 19 November 2018

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Article Open Access

Pathways regulating the expression of the immunomodulatory protein glycodelin in non‑small cell lung cancer

Rebecca Weber, Michael Meister, Thomas Muley, Michael Thomas, Holger Sültmann, Arne Warth, Hauke Winter, Felix J.F. Herth, Marc A. Schneider
Pages: 515-526
Published online on: 05 December 2018

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Article Open Access

Targeting retinoblastoma protein phosphorylation in combination with EGFR inhibition in pancreatic cancer cells

Nimmi A. Thomas, Rita G. Abraham, Brixhilda Dedi, Nancy A. Krucher
Pages: 527-536
Published online on: 07 December 2018

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Article Open Access

Silencing of caveolin-1 in fibroblasts as opposed to epithelial tumor cells results in increased tumor growth rate and chemoresistance in a human pancreatic cancer model

Konstantinos Kamposioras, Chrysiida Tsimplouli, Caroline Verbeke, Alan Anthoney, Argyro Daoukopoulou, Christos N. Papandreou, Nikolaos Sakellaridis, George Vassilopoulos, Spyros P. Potamianos, Vasiliki Liakouli, Gemma Migneco, Francesco Del Galdo, Konstantinos Dimas
Pages: 537-549
Published online on: 21 November 2018

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Article Open Access

Phosphorylation of cortactin by cyclin-dependent kinase 5 modulates actin bundling by the dynamin 1-cortactin ring-like complex and formation of filopodia and lamellipodia in NG108-15 glioma-derived cells Corrigendum in /10.3892/ijo.2020.4962

Tadashi Abe, The Mon La, Yuuzi Miyagaki, Eri Oya, Fan-Yan Wei, Kento Sumida, Kenshiro Fujise, Tetsuya Takeda, Kazuhito Tomizawa, Kohji Takei, Hiroshi Yamada
Pages: 550-558
Published online on: 11 December 2018

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Article Open Access

miR‑122 promotes proliferation and invasion of clear cell renal cell carcinoma by suppressing Forkhead box O3 Corrigendum in /10.3892/ijo.2019.4694

Wenyuan Nie, Dong Ni, Xin Ma, Yu Zhang, Yu Gao, Cheng Peng, Xu Zhang
Pages: 559-571
Published online on: 19 November 2018

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Article Open Access

OxLDL promotes lymphangiogenesis and lymphatic metastasis in gastric cancer by upregulating VEGF‑C expression and secretion

Caiqi Ma, Jinye Xie, Chuanghua Luo, Haofan Yin, Ruopu Li, Xi Wang, Wenjun Xiong, Ting Zhang, Ping Jiang, Weiwei Qi, Ti Zhou, Zhonghan Yang, Wei Wang, Jianxing Ma, Guoquan Gao, Xia Yang
Pages: 572-584
Published online on: 26 November 2018

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Article Open Access

CD38 affects the biological behavior and energy metabolism of nasopharyngeal carcinoma cells

Yanshan Ge, Yuehua Long, Songshu Xiao, Lin Liang, Zhengxi He, Chunxue Yue, Xiong Wei, Yanhong Zhou
Pages: 585-599
Published online on: 03 December 2018

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Article Open Access

Potential ceRNA networks involved in autophagy suppression of pancreatic cancer caused by chloroquine diphosphate: A study based on differentially‑expressed circRNAs, lncRNAs, miRNAs and mRNAs

Dan‑Ming Wei, Meng‑Tong Jiang, Peng Lin, Hong Yang, Yi‑Wu Dang, Qiao Yu, Dan‑Yu Liao, Dian‑Zhong Luo, Gang Chen
Pages: 600-626
Published online on: 10 December 2018

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Article Open Access

Oncological hyperthermia: The correct dosing in clinical applications

Sun-Young Lee, Gyula Peter Szigeti, Attila Marcell Szasz
Pages: 627-643
Published online on: 23 November 2018

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Article

Methylation‑associated silencing of miR‑128 promotes the development of esophageal cancer by targeting COX‑2 in areas with a high incidence of esophageal cancer

Jing Jin, Tiantian Guo, Yongdong Guo, Jianghui Liu, Feng Qu, Yutong He
Pages: 644-654
Published online on: 04 December 2018

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Article

Evaluation of chemotherapeutic and cancer-protective properties of sphingosine and C2-ceramide in a human breast stem cell derived carcinogenesis model

Eun Hyun Ahn, Hong Yang, Ching-Yi Hsieh, Wei Sun, Chia-Cheng Chang, Joseph J. Schroeder
Pages: 655-664
Published online on: 22 November 2018

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Article

Luteolin sensitizes human liver cancer cells to TRAIL‑induced apoptosis via autophagy and JNK‑mediated death receptor 5 upregulation

Uddin Md. Nazim, Sang‑Youel Park
Pages: 665-672
Published online on: 14 November 2018

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Article

Molecular pathogenesis of esophageal squamous cell carcinoma: Identification of the antitumor effects of miR‑145‑3p on gene regulation

Masataka Shimonosono, Tetsuya Idichi, Naohiko Seki, Yasutaka Yamada, Takayuki Arai, Takaaki Arigami, Ken Sasaki, Itaru Omoto, Yasuto Uchikado, Yoshiaki Kita, Hiroshi Kurahara, Kosei Maemura, Shoji Natsugoe
Pages: 673-688
Published online on: 06 December 2018

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Article

MicroRNA‑143‑3p suppresses cell growth and invasion in laryngeal squamous cell carcinoma via targeting the k‑Ras/Raf/MEK/ERK signaling pathway

Feng Zhang, Hua Cao
Pages: 689-701
Published online on: 06 December 2018

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Article

Inhibitory role of AMP‑activated protein kinase in necroptosis of HCT116 colon cancer cells with p53 null mutation under nutrient starvation

Dan‑Diem Thi Le, Samil Jung, Nguyen Thi Ngoc Quynh, Zolzaya Sandag, Beom Suk Lee, Subeen Kim, Hyegyeong Lee, Hyojeong Lee, Myeong‑Sok Lee
Pages: 702-712
Published online on: 14 November 2018

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Article

Exosomal lncRNA‑ATB activates astrocytes that promote glioma cell invasion

Er‑Bao Bian, Er‑Feng Chen, Ya‑Di Xu, Zhi‑Hao Yang, Feng Tang, Chun‑Chun Ma, Hong‑Liang Wang, Bing Zhao
Pages: 713-721
Published online on: 23 November 2018

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Article

EphA3 inhibits migration and invasion of esophageal cancer cells by activating the mesenchymal‑epithelial transition process

Xia Chen, Bin Lu, Qian Ma, Cheng‑Dong Ji, Jian‑Zhong Li
Pages: 722-732
Published online on: 21 November 2018

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Article

miR‑381 and miR‑489 suppress cell proliferation and invasion by targeting CUL4B via the Wnt/β‑catenin pathway in gastric cancer

Ziling Fang, Min Zhong, Yi Wang, Xiang Yuan, Hui Guo, Yangyang Yao, Miao Feng, Jun Chen, Jianping Xiong, Xiaojun Xiang
Pages: 733-743
Published online on: 26 November 2018

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Article

The association of changes in RAD51 and survivin expression levels with the proton beam sensitivity of Capan‑1 and Panc‑1 human pancreatic cancer cells

Min‑Gu Lee, Kyu‑Shik Lee, Kyung‑Soo Nam
Pages: 744-752
Published online on: 22 November 2018

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Article

The oncometabolite d‑2‑hydroxyglutarate induces angiogenic activity through the vascular endothelial growth factor receptor 2 signaling pathway

Jiyoon Seok, Soo‑Hyun Yoon, Sun‑Hee Lee, Jong Hwa Jung, You Mie Lee
Pages: 753-763
Published online on: 27 November 2018

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Article

Mechanisms of metformin's anti‑tumor activity against gemcitabine‑resistant pancreatic adenocarcinoma

Keiichi Suzuki, Osamu Takeuchi, Yukio Suzuki, Yuko Kitagawa
Pages: 764-772
Published online on: 10 December 2018

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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