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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2019 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Mitotane induces mitochondrial membrane depolarization and apoptosis in thyroid cancer cells

Athanasios Bikas, Kirk Jensen, Aneeta Patel, John Costello, Gregory Kaltsas, Victoria Hoperia, Leonard Wartofsky, Kenneth Burman, Vasyl Vasko
Pages: 7-20
Published online on: 16 May 2019

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Article Open Access

Downregulated LRRK2 gene expression inhibits proliferation and migration while promoting the apoptosis of thyroid cancer cells by inhibiting activation of the JNK signaling pathway

Zheng‑Cai Jiang, Xiao‑Jun Chen, Qi Zhou, Xiao‑Hua Gong, Xiong Chen, Wen‑Jun Wu
Pages: 21-34
Published online on: 29 May 2019

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Article Open Access

S100A9 promotes the proliferation and migration of cervical cancer cells by inducing epithelial‑mesenchymal transition and activating the Wnt/β‑catenin pathway

He Zha, Xueru Li, Hui Sun, Liang Duan, Shimei Yuan, Huan Li, Aifang Li, Yue Gu, Jiali Zhao, Jiaqing Xie, Lan Zhou
Pages: 35-44
Published online on: 02 May 2019

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Article Open Access

lnc-PKD2-2-3, identified by long non-coding RNA expression profiling, is associated with pejorative tumor features and poor prognosis, enhances cancer stemness and may serve as cancer stem-cell marker in cholangiocarcinoma

Gongcai Qiu, Donglai Ma, Fujun Li, Dongsheng Sun, Zhaolin Zeng
Pages: 45-58
Published online on: 06 May 2019

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Article Open Access

Targeting miR‑155‑5p and miR‑221‑3p by peptide nucleic acids induces caspase‑3 activation and apoptosis in temozolomide‑resistant T98G glioma cells

Roberta Milani, Eleonora Brognara, Enrica Fabbri, Alex Manicardi, Roberto Corradini, Alessia Finotti, Jessica Gasparello, Monica Borgatti, Lucia Carmela Cosenza, Ilaria Lampronti, Maria Cristina Dechecchi, Giulio Cabrini, Roberto Gambari
Pages: 59-68
Published online on: 23 May 2019

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Article Open Access

Extracellular RNAs from lung cancer cells activate epithelial cells and induce neutrophil extracellular traps

Yan Li, Yonglin Yang, Tingting Gan, Jiawei Zhou, Fan Hu, Nannan Hao, Baorui Yuan, Yu Chen, Mingshun Zhang
Pages: 69-80
Published online on: 21 May 2019

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Article Open Access

PLEKHO1 knockdown inhibits RCC cell viability in vitro and in vivo, potentially by the Hippo and MAPK/JNK pathways

Zi Yu, Qiang Li, Gejun Zhang, Chengcheng Lv, Qingzhuo Dong, Cheng Fu, Chuize Kong, Yu Zeng
Pages: 81-92
Published online on: 30 May 2019

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Article Open Access

lncRNA SNHG16 is associated with proliferation and poor prognosis of pediatric neuroblastoma

Yongbo Yu, Feng Chen, Yeran Yang, Yaqiong Jin, Jin Shi, Shujing Han, Ping Chu, Jie Lu, Jun Tai, Shengcai Wang, Wei Yang, Huanmin Wang, Yongli Guo, Xin Ni
Pages: 93-102
Published online on: 24 May 2019

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Article Open Access

Overexpression of Sirt6 promotes M2 macrophage transformation, alleviating renal injury in diabetic nephropathy

Liqiang Ji, Yifang Chen, Hongqiang Wang, Wei Zhang, Lanxiang He, Jingmin Wu, Yinghui Liu
Pages: 103-115
Published online on: 14 May 2019

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Article Open Access

Class I histone deacetylase inhibitor suppresses vasculogenic mimicry by enhancing the expression of tumor suppressor and anti-angiogenesis genes in aggressive human TNBC cells

Aparna Maiti, Qianya Qi, Xuan Peng, Li Yan, Kazuaki Takabe, Nitai C. Hait
Pages: 116-130
Published online on: 06 May 2019

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Article Open Access

Serum bradykinin levels as a diagnostic marker in cervical cancer with a potential mechanism to promote VEGF expression via BDKRB2

Ying Zhou, Wei Wang, Rui Wei, Guiying Jiang, Fei Li, Xi Chen, Xueqian Wang, Sixiang Long, Ding Ma, Ling Xi
Pages: 131-141
Published online on: 02 May 2019

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Article Open Access

MicroRNA hsa-miR-623 directly suppresses MMP1 and attenuates IL-8-induced metastasis in pancreatic cancer

Yutong Chen, Siqi Peng, Hong Cen, Yujing Lin, Chumei Huang, Yinting Chen, Hong Shan, Yonghui Su, Linjuan Zeng
Pages: 142-156
Published online on: 17 May 2019

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Article

Activated androgen receptor accelerates angiogenesis in cutaneous neurofibroma by regulating VEGFA transcription

Jing Jia, Haibao Zhang, Hongke Zhang, Huicong Du, Wenbo Liu, Maoguo Shu
Pages: 157-166
Published online on: 06 May 2019

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Article

Epigenetic modulators hydralazine and sodium valproate act synergistically in VEGI-mediated anti-angiogenesis and VEGF interference in human osteosarcoma and vascular endothelial cells

Shunsuke Kumanishi, Koji Yamanegi, Hiroshi Nishiura, Yuki Fujihara, Kenta Kobayashi, Keiji Nakasho, Hiroyuki Futani, Shinichi Yoshiya
Pages: 167-178
Published online on: 23 May 2019

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Article

Epithelial ovarian cancer stem‑like cells are resistant to the cellular lysis of cytokine‑induced killer cells via HIF1A‑mediated downregulation of ICAM‑1

Shixia Bu, Boning Li, Qian Wang, Tingting Gu, Qianggang Dong, Xiaofei Miao, Dongmei Lai
Pages: 179-190
Published online on: 03 May 2019

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Article

The XIAP inhibitor embelin sensitises malignant rhabdoid tumour cells to TRAIL treatment via enhanced activation of the extrinsic apoptotic pathway

Rachel Coyle, Karen Slattery, Leanne Ennis, Maureen J. O'sullivan, Daniela M. Zisterer
Pages: 191-202
Published online on: 20 May 2019

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Article

Inhibition of JAK2/STAT3 and activation of caspase‑9/3 are involved in KYS05090S‑induced apoptosis in ovarian cancer cells

Bo‑Im Kim, Ju‑Ha Kim, Deok Yong Sim, Minho Nam, Ji Hoon Jung, Bumsang Shim, Jaeyeol Lee, Sung‑Hoon Kim
Pages: 203-210
Published online on: 03 May 2019

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Article

S100P regulates the collective invasion of pancreatic cancer cells into the lymphatic endothelial monolayer

Hiromichi Nakayama, Kenoki Ohuchida, Akiko Yonenaga, Akiko Sagara, Yohei Ando, Shin Kibe, Shin Takesue, Toshiya Abe, Sho Endo, Kazuhiro Koikawa, Takashi Okumura, Koji Shido, Kei Miyoshi, Kohei Nakata, Taiki Moriyama, Yoshihiro Miyasaka, Shigetaka Inoue, Takao Ohtsuka, Kazuhiro Mizumoto, Masafumi Nakamura
Pages: 211-222
Published online on: 24 May 2019

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Article

Effects of 5-FU and anti-EGFR antibody in combination with ASA on the spherical culture system of HCT116 and HT29 colorectal cancer cell lines

Agata Olejniczak-Kęder, Magdalena Szaryńska, Agata Wrońska, Kamila Siedlecka-Kroplewska, Zbigniew Kmieć
Pages: 223-242
Published online on: 23 May 2019

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Article Open Access

Establishment and characterization of a novel cell line (cc‑006cpm8) of moderately/poorly differentiated colorectal adenocarcinoma derived from a primary tumor of a patient

Xia Chu, Yiqi Xue, Xinying Huo, Jingsun Wei, Yuetong Chen, Rongbo Han, Hong Chen, Xinyu Su, Honghong Zhang, Yang Gong, Jinfei Chen
Pages: 243-256
Published online on: 21 May 2019

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Article

CENPE promotes lung adenocarcinoma proliferation and is directly regulated by FOXM1 Corrigendum in /10.3892/ijo.2019.4872

Lina Shan, Minjie Zhao, Ya Lu, Hongjuan Ning, Shuman Yang, Yonggui Song, Wenshu Chai, Xianbao Shi
Pages: 257-266
Published online on: 20 May 2019

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Article

Transforming growth factor‑β/miR‑143‑3p/cystatin B axis is a therapeutic target in human ovarian cancer

Wencai Guan, Xingxing Wang, Qunbo Lin, Jinguo Zhang, Weimin Ren, Guoxiong Xu
Pages: 267-276
Published online on: 28 May 2019

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Article

USP39 promotes ovarian cancer malignant phenotypes and carboplatin chemoresistance

Lingzhi Wang, Tanxiu Chen, Xukun Li, Wei Yan, Yanhui Lou, Zhihua Liu, Hongyan Chen, Zhumei Cui
Pages: 277-288
Published online on: 29 May 2019

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Article

PF‑114, a novel selective inhibitor of BCR‑ABL tyrosine kinase, is a potent inducer of apoptosis in chronic myelogenous leukemia cells

Ekaterina S. Ivanova, Victor V. Tatarskiy, Margarita A. Yastrebova, Alvina I. Khamidullina, Alexei V. Shunaev, Anastasia A. Kalinina, Alexei A. Zeifman, Fedor N. Novikov, Yulia V. Dutikova, Ghermes G. Chilov, Alexander A. Shtil
Pages: 289-297
Published online on: 14 May 2019

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Article

Leptin stimulates the epithelial‑mesenchymal transition and pro‑angiogenic capability of cholangiocarcinoma cells through the miR‑122/PKM2 axis

Chuang Peng, Zengpeng Sun, Ou Li, Chao Guo, Weimin Yi, Zhaoxia Tan, Bo Jiang
Pages: 298-308
Published online on: 21 May 2019

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Article

Potent and specific fusion toxins consisting of a HER2‑binding, ABD‑derived affinity protein, fused to truncated versions of Pseudomonas exotoxin A

Hao Liu, Sarah Lindbo, Haozhong Ding, Mohamed Altai, Javad Garousi, Anna Orlova, Vladimir Tolmachev, Sophia Hober, Torbjörn Gräslund
Pages: 309-319
Published online on: 28 May 2019

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Article

Suppression of EGFR/STAT3 activity by lupeol contributes to the induction of the apoptosis of human non‑small cell lung cancer cells

Tae‑Rin Min, Hyun‑Ji Park, Ki‑Tae Ha, Gyoo‑Yong Chi, Yung‑Hyun Choi, Shin‑Hyung Park
Pages: 320-330
Published online on: 07 May 2019

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Article

Metformin induces TPC-1 cell apoptosis through endoplasmic reticulum stress-associated pathways in vitro and in vivo

Jianwen Ye, Lei Qi, Kunlun Chen, Renfeng Li, Shengping Song, Chuang Zhou, Wenlong Zhai
Pages: 331-339
Published online on: 31 May 2019

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Correction Open Access

[Corrigendum] Overexpression of lncRNA EGFR‑AS1 is associated with a poor prognosis and promotes chemotherapy resistance in non‑small cell lung cancer

Yu-Hua Xu, Jian-Ren Tu, Tian-Tian Zhao, Shi-Guang Xie, Sheng-Bo Tang
Pages: 340-340
Published online on: 14 January 2019

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Journal Cover
September-2026 Volume 69 Issue 3

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

The role of deubiquitinating enzymes and their inhibitors in esophageal carcinoma (Review)

Yu Zhao, Chenghai He, Kexin Chen, Nanting Sun, Ruonan He, Guodong Li
Article Number: 108
Published online on: 16 July 2026

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Correction Open Access

[Corrigendum] AHIF promotes glioblastoma progression and radioresistance via exosomes

Xuejun Dai, Keman Liao, Zhijun Zhuang, Binghong Chen, Zhiyi Zhou, Sunhai Zhou, Guoshi Lin, Feifei Zhang, Yingying Lin, Yifeng Miao, Zhiqiang Li, Renhua Huang, Yongming Qiu, Ruisheng Lin
Article Number: 107
Published online on: 15 July 2026

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Article Open Access

Triptonide enhances DNA damage by inhibiting TRIP13‑mediated DNA repair and synergizes with bortezomib to suppress multiple myeloma

Fen He, Junjun Li, Lijun Peng, Hongyan Zhao, Maoyou Lu, Ruixin Gao, Siqi Wang, Yu Chen, Ruihan Tang, Zhengguo Li, Linlin Zhang, Xinyu Zhang, Qianhao Li, Weihui Chen, Jiayu Liu, Cong Luo, Xi Zeng, Jiliang Xia
Article Number: 106
Published online on: 14 July 2026

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Article Open Access

YAP1‑mediated cytoplasmic‑nuclear translocation of SREBP2 promotes colorectal cancer via regulation of cholesterol metabolism

Luhui Zhong, Min Sun, Di Wu, Yulan Zeng, Min Zhou, Rui Gong, Feifei Gu, Kai Zhang, Xiaoyan Hu, Yue Hu
Article Number: 105
Published online on: 13 July 2026

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Review Open Access

Immunoediting and precision biomarkers in prostate cancer: The emerging role of liquid biopsy, immune contexture and HLA genotype (Review)

Constantin N. Baxevanis, Savvas Stokidis, Sotirios P. Fortis, Maria Goulielmaki, Ourania E. Tsitsilonis, Angelos D. Gritzapis
Article Number: 104
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples

Giovanni Luca Gravina, Andrea Mancini, Guido Ranieri, Boris Di Pasquale, Francesco Marampon, Luigi Di Clemente, Enrico Ricevuto, Claudio Festuccia
Article Number: 103
Published online on: 13 July 2026

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Review Open Access

The neural stem cell‑NSCLC axis: Molecular drivers, microenvironment crosstalk and emerging therapies (Review)

Yanling Xu, Hanmei Duan, Peng Lu, Feng Liu
Article Number: 102
Published online on: 10 July 2026

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Review Open Access

TGF‑β1 in cancer: From tumour suppressor to promoter, molecular mechanisms, and precision therapeutic strategies (Review)

Chao Huang
Article Number: 101
Published online on: 10 July 2026

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Article Open Access

T‑box transcription factor 15 regulated by methyltransferase‑like 3‑mediated N6‑methyladenosine modification promotes immune escape and progression of gastric cancer by activating matrix metalloproteinase 14 transcription

Hongsai Hu, Rong He, Minji Liu, Xuli Liu, Qiongjia Ai, Min Chen, Qian Wang, Wenhui Chen, Weiming Qu
Article Number: 100
Published online on: 09 July 2026

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Review Open Access

Glycolysis‑driven immunosuppression in gastric cancer: Metabolic crosstalk between tumor cells and the immune microenvironment (Review)

Bo Zhang, Lihan Shang, Ziyu Kuang, Chaoran Wang, Bingsheng Sun, Fanming Kong
Article Number: 99
Published online on: 09 July 2026

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Review Open Access

New insights into the physiological, pathological and pharmacological roles of voltage‑gated potassium channel Kv10.1 in cancer (Review)

Yuxiao Zhen, Weibo Hu, Shanshan Dong, Bochang Wang, Jian Shen, Leyuan Ding, Lifeng Li, Hailong An, Xuzhao Wang, Yafei Chen
Article Number: 98
Published online on: 09 July 2026

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Retraction Open Access

[Retracted] Glycyrrhetinic acid induces G1‑phase cell cycle arrest in human non‑small cell lung cancer cells through endoplasmic reticulum stress pathway

Jie Zhu, Meijuan Chen, Ning Chen, Aizhen Ma, Chunyan Zhu, Ruolin Zhao, Miao Jiang, Jing Zhou, Lihong Ye, Haian Fu, Xu Zhang
Article Number: 97
Published online on: 06 July 2026

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Journal Cover
October-2026 Volume 69 Issue 4

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Correction Open Access

[Corrigendum] Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines

Nesstor Pilco‑Ferreto, Gloria   M. Calaf
Article Number: 110
Published online on: 20 July 2026

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Article Open Access

Evaluation of Punicalagin as a multi‑targeted therapeutic agent against endometrial cancer

Zeeshan Ahmad Bhutta, Dohee Ahn, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 109
Published online on: 17 July 2026

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