Journal Articles
Article
Mitotane induces mitochondrial membrane depolarization and apoptosis in thyroid cancer cells
Athanasios Bikas, Kirk Jensen, Aneeta Patel, John Costello, Gregory Kaltsas, Victoria Hoperia, Leonard Wartofsky, Kenneth Burman, Vasyl Vasko
Pages: 7-20 Published online on: 16 May 2019
Article
Downregulated LRRK2 gene expression inhibits proliferation and migration while promoting the apoptosis of thyroid cancer cells by inhibiting activation of the JNK signaling pathway
Zheng‑Cai Jiang, Xiao‑Jun Chen, Qi Zhou, Xiao‑Hua Gong, Xiong Chen, Wen‑Jun Wu
Pages: 21-34 Published online on: 29 May 2019
Article
S100A9 promotes the proliferation and migration of cervical cancer cells by inducing epithelial‑mesenchymal transition and activating the Wnt/β‑catenin pathway
He Zha, Xueru Li, Hui Sun, Liang Duan, Shimei Yuan, Huan Li, Aifang Li, Yue Gu, Jiali Zhao, Jiaqing Xie, Lan Zhou
Pages: 35-44 Published online on: 02 May 2019
Article
lnc-PKD2-2-3, identified by long non-coding RNA expression profiling, is associated with pejorative tumor features and poor prognosis, enhances cancer stemness and may serve as cancer stem-cell marker in cholangiocarcinoma
Gongcai Qiu, Donglai Ma, Fujun Li, Dongsheng Sun, Zhaolin Zeng
Pages: 45-58 Published online on: 06 May 2019
Article
Targeting miR‑155‑5p and miR‑221‑3p by peptide nucleic acids induces caspase‑3 activation and apoptosis in temozolomide‑resistant T98G glioma cells
Roberta Milani, Eleonora Brognara, Enrica Fabbri, Alex Manicardi, Roberto Corradini, Alessia Finotti, Jessica Gasparello, Monica Borgatti, Lucia Carmela Cosenza, Ilaria Lampronti, Maria Cristina Dechecchi, Giulio Cabrini, Roberto Gambari
Pages: 59-68 Published online on: 23 May 2019
Article
Extracellular RNAs from lung cancer cells activate epithelial cells and induce neutrophil extracellular traps
Yan Li, Yonglin Yang, Tingting Gan, Jiawei Zhou, Fan Hu, Nannan Hao, Baorui Yuan, Yu Chen, Mingshun Zhang
Pages: 69-80 Published online on: 21 May 2019
Article
PLEKHO1 knockdown inhibits RCC cell viability in vitro and in vivo, potentially by the Hippo and MAPK/JNK pathways
Zi Yu, Qiang Li, Gejun Zhang, Chengcheng Lv, Qingzhuo Dong, Cheng Fu, Chuize Kong, Yu Zeng
Pages: 81-92 Published online on: 30 May 2019
Article
lncRNA SNHG16 is associated with proliferation and poor prognosis of pediatric neuroblastoma
Yongbo Yu, Feng Chen, Yeran Yang, Yaqiong Jin, Jin Shi, Shujing Han, Ping Chu, Jie Lu, Jun Tai, Shengcai Wang, Wei Yang, Huanmin Wang, Yongli Guo, Xin Ni
Pages: 93-102 Published online on: 24 May 2019
Article
Overexpression of Sirt6 promotes M2 macrophage transformation, alleviating renal injury in diabetic nephropathy
Liqiang Ji, Yifang Chen, Hongqiang Wang, Wei Zhang, Lanxiang He, Jingmin Wu, Yinghui Liu
Pages: 103-115 Published online on: 14 May 2019
Article
Class I histone deacetylase inhibitor suppresses vasculogenic mimicry by enhancing the expression of tumor suppressor and anti-angiogenesis genes in aggressive human TNBC cells
Aparna Maiti, Qianya Qi, Xuan Peng, Li Yan, Kazuaki Takabe, Nitai C. Hait
Pages: 116-130 Published online on: 06 May 2019
Article
Serum bradykinin levels as a diagnostic marker in cervical cancer with a potential mechanism to promote VEGF expression via BDKRB2
Ying Zhou, Wei Wang, Rui Wei, Guiying Jiang, Fei Li, Xi Chen, Xueqian Wang, Sixiang Long, Ding Ma, Ling Xi
Pages: 131-141 Published online on: 02 May 2019
Article
MicroRNA hsa-miR-623 directly suppresses MMP1 and attenuates IL-8-induced metastasis in pancreatic cancer
Yutong Chen, Siqi Peng, Hong Cen, Yujing Lin, Chumei Huang, Yinting Chen, Hong Shan, Yonghui Su, Linjuan Zeng
Pages: 142-156 Published online on: 17 May 2019
Article
Activated androgen receptor accelerates angiogenesis in cutaneous neurofibroma by regulating VEGFA transcription
Jing Jia, Haibao Zhang, Hongke Zhang, Huicong Du, Wenbo Liu, Maoguo Shu
Pages: 157-166 Published online on: 06 May 2019
Article
Epigenetic modulators hydralazine and sodium valproate act synergistically in VEGI-mediated anti-angiogenesis and VEGF interference in human osteosarcoma and vascular endothelial cells
Shunsuke Kumanishi, Koji Yamanegi, Hiroshi Nishiura, Yuki Fujihara, Kenta Kobayashi, Keiji Nakasho, Hiroyuki Futani, Shinichi Yoshiya
Pages: 167-178 Published online on: 23 May 2019
Article
Epithelial ovarian cancer stem‑like cells are resistant to the cellular lysis of cytokine‑induced killer cells via HIF1A‑mediated downregulation of ICAM‑1
Shixia Bu, Boning Li, Qian Wang, Tingting Gu, Qianggang Dong, Xiaofei Miao, Dongmei Lai
Pages: 179-190 Published online on: 03 May 2019
Article
The XIAP inhibitor embelin sensitises malignant rhabdoid tumour cells to TRAIL treatment via enhanced activation of the extrinsic apoptotic pathway
Rachel Coyle, Karen Slattery, Leanne Ennis, Maureen J. O'sullivan, Daniela M. Zisterer
Pages: 191-202 Published online on: 20 May 2019
Article
Inhibition of JAK2/STAT3 and activation of caspase‑9/3 are involved in KYS05090S‑induced apoptosis in ovarian cancer cells
Bo‑Im Kim, Ju‑Ha Kim, Deok Yong Sim, Minho Nam, Ji Hoon Jung, Bumsang Shim, Jaeyeol Lee, Sung‑Hoon Kim
Pages: 203-210 Published online on: 03 May 2019
Article
S100P regulates the collective invasion of pancreatic cancer cells into the lymphatic endothelial monolayer
Hiromichi Nakayama, Kenoki Ohuchida, Akiko Yonenaga, Akiko Sagara, Yohei Ando, Shin Kibe, Shin Takesue, Toshiya Abe, Sho Endo, Kazuhiro Koikawa, Takashi Okumura, Koji Shido, Kei Miyoshi, Kohei Nakata, Taiki Moriyama, Yoshihiro Miyasaka, Shigetaka Inoue, Takao Ohtsuka, Kazuhiro Mizumoto, Masafumi Nakamura
Pages: 211-222 Published online on: 24 May 2019
Article
Effects of 5-FU and anti-EGFR antibody in combination with ASA on the spherical culture system of HCT116 and HT29 colorectal cancer cell lines
Agata Olejniczak-Kęder, Magdalena Szaryńska, Agata Wrońska, Kamila Siedlecka-Kroplewska, Zbigniew Kmieć
Pages: 223-242 Published online on: 23 May 2019
Article
Establishment and characterization of a novel cell line (cc‑006cpm8) of moderately/poorly differentiated colorectal adenocarcinoma derived from a primary tumor of a patient
Xia Chu, Yiqi Xue, Xinying Huo, Jingsun Wei, Yuetong Chen, Rongbo Han, Hong Chen, Xinyu Su, Honghong Zhang, Yang Gong, Jinfei Chen
Pages: 243-256 Published online on: 21 May 2019
Article
CENPE promotes lung adenocarcinoma proliferation and is directly regulated by FOXM1 Corrigendum in /10.3892/ijo.2019.4872
Lina Shan, Minjie Zhao, Ya Lu, Hongjuan Ning, Shuman Yang, Yonggui Song, Wenshu Chai, Xianbao Shi
Pages: 257-266 Published online on: 20 May 2019
Article
Transforming growth factor‑β/miR‑143‑3p/cystatin B axis is a therapeutic target in human ovarian cancer
Wencai Guan, Xingxing Wang, Qunbo Lin, Jinguo Zhang, Weimin Ren, Guoxiong Xu
Pages: 267-276 Published online on: 28 May 2019
Article
USP39 promotes ovarian cancer malignant phenotypes and carboplatin chemoresistance
Lingzhi Wang, Tanxiu Chen, Xukun Li, Wei Yan, Yanhui Lou, Zhihua Liu, Hongyan Chen, Zhumei Cui
Pages: 277-288 Published online on: 29 May 2019
Article
PF‑114, a novel selective inhibitor of BCR‑ABL tyrosine kinase, is a potent inducer of apoptosis in chronic myelogenous leukemia cells
Ekaterina S. Ivanova, Victor V. Tatarskiy, Margarita A. Yastrebova, Alvina I. Khamidullina, Alexei V. Shunaev, Anastasia A. Kalinina, Alexei A. Zeifman, Fedor N. Novikov, Yulia V. Dutikova, Ghermes G. Chilov, Alexander A. Shtil
Pages: 289-297 Published online on: 14 May 2019
Article
Leptin stimulates the epithelial‑mesenchymal transition and pro‑angiogenic capability of cholangiocarcinoma cells through the miR‑122/PKM2 axis
Chuang Peng, Zengpeng Sun, Ou Li, Chao Guo, Weimin Yi, Zhaoxia Tan, Bo Jiang
Pages: 298-308 Published online on: 21 May 2019
Article
Potent and specific fusion toxins consisting of a HER2‑binding, ABD‑derived affinity protein, fused to truncated versions of Pseudomonas exotoxin A
Hao Liu, Sarah Lindbo, Haozhong Ding, Mohamed Altai, Javad Garousi, Anna Orlova, Vladimir Tolmachev, Sophia Hober, Torbjörn Gräslund
Pages: 309-319 Published online on: 28 May 2019
Article
Suppression of EGFR/STAT3 activity by lupeol contributes to the induction of the apoptosis of human non‑small cell lung cancer cells
Tae‑Rin Min, Hyun‑Ji Park, Ki‑Tae Ha, Gyoo‑Yong Chi, Yung‑Hyun Choi, Shin‑Hyung Park
Pages: 320-330 Published online on: 07 May 2019
Article
Metformin induces TPC-1 cell apoptosis through endoplasmic reticulum stress-associated pathways in vitro and in vivo
Jianwen Ye, Lei Qi, Kunlun Chen, Renfeng Li, Shengping Song, Chuang Zhou, Wenlong Zhai
Pages: 331-339 Published online on: 31 May 2019
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