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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2019 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Mitotane induces mitochondrial membrane depolarization and apoptosis in thyroid cancer cells

Athanasios Bikas, Kirk Jensen, Aneeta Patel, John Costello, Gregory Kaltsas, Victoria Hoperia, Leonard Wartofsky, Kenneth Burman, Vasyl Vasko
Pages: 7-20
Published online on: 16 May 2019

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Article Open Access

Downregulated LRRK2 gene expression inhibits proliferation and migration while promoting the apoptosis of thyroid cancer cells by inhibiting activation of the JNK signaling pathway

Zheng‑Cai Jiang, Xiao‑Jun Chen, Qi Zhou, Xiao‑Hua Gong, Xiong Chen, Wen‑Jun Wu
Pages: 21-34
Published online on: 29 May 2019

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Article Open Access

S100A9 promotes the proliferation and migration of cervical cancer cells by inducing epithelial‑mesenchymal transition and activating the Wnt/β‑catenin pathway

He Zha, Xueru Li, Hui Sun, Liang Duan, Shimei Yuan, Huan Li, Aifang Li, Yue Gu, Jiali Zhao, Jiaqing Xie, Lan Zhou
Pages: 35-44
Published online on: 02 May 2019

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Article Open Access

lnc-PKD2-2-3, identified by long non-coding RNA expression profiling, is associated with pejorative tumor features and poor prognosis, enhances cancer stemness and may serve as cancer stem-cell marker in cholangiocarcinoma

Gongcai Qiu, Donglai Ma, Fujun Li, Dongsheng Sun, Zhaolin Zeng
Pages: 45-58
Published online on: 06 May 2019

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Article Open Access

Targeting miR‑155‑5p and miR‑221‑3p by peptide nucleic acids induces caspase‑3 activation and apoptosis in temozolomide‑resistant T98G glioma cells

Roberta Milani, Eleonora Brognara, Enrica Fabbri, Alex Manicardi, Roberto Corradini, Alessia Finotti, Jessica Gasparello, Monica Borgatti, Lucia Carmela Cosenza, Ilaria Lampronti, Maria Cristina Dechecchi, Giulio Cabrini, Roberto Gambari
Pages: 59-68
Published online on: 23 May 2019

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Article Open Access

Extracellular RNAs from lung cancer cells activate epithelial cells and induce neutrophil extracellular traps

Yan Li, Yonglin Yang, Tingting Gan, Jiawei Zhou, Fan Hu, Nannan Hao, Baorui Yuan, Yu Chen, Mingshun Zhang
Pages: 69-80
Published online on: 21 May 2019

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Article Open Access

PLEKHO1 knockdown inhibits RCC cell viability in vitro and in vivo, potentially by the Hippo and MAPK/JNK pathways

Zi Yu, Qiang Li, Gejun Zhang, Chengcheng Lv, Qingzhuo Dong, Cheng Fu, Chuize Kong, Yu Zeng
Pages: 81-92
Published online on: 30 May 2019

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Article Open Access

lncRNA SNHG16 is associated with proliferation and poor prognosis of pediatric neuroblastoma

Yongbo Yu, Feng Chen, Yeran Yang, Yaqiong Jin, Jin Shi, Shujing Han, Ping Chu, Jie Lu, Jun Tai, Shengcai Wang, Wei Yang, Huanmin Wang, Yongli Guo, Xin Ni
Pages: 93-102
Published online on: 24 May 2019

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Article Open Access

Overexpression of Sirt6 promotes M2 macrophage transformation, alleviating renal injury in diabetic nephropathy

Liqiang Ji, Yifang Chen, Hongqiang Wang, Wei Zhang, Lanxiang He, Jingmin Wu, Yinghui Liu
Pages: 103-115
Published online on: 14 May 2019

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Article Open Access

Class I histone deacetylase inhibitor suppresses vasculogenic mimicry by enhancing the expression of tumor suppressor and anti-angiogenesis genes in aggressive human TNBC cells

Aparna Maiti, Qianya Qi, Xuan Peng, Li Yan, Kazuaki Takabe, Nitai C. Hait
Pages: 116-130
Published online on: 06 May 2019

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Article Open Access

Serum bradykinin levels as a diagnostic marker in cervical cancer with a potential mechanism to promote VEGF expression via BDKRB2

Ying Zhou, Wei Wang, Rui Wei, Guiying Jiang, Fei Li, Xi Chen, Xueqian Wang, Sixiang Long, Ding Ma, Ling Xi
Pages: 131-141
Published online on: 02 May 2019

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Article Open Access

MicroRNA hsa-miR-623 directly suppresses MMP1 and attenuates IL-8-induced metastasis in pancreatic cancer

Yutong Chen, Siqi Peng, Hong Cen, Yujing Lin, Chumei Huang, Yinting Chen, Hong Shan, Yonghui Su, Linjuan Zeng
Pages: 142-156
Published online on: 17 May 2019

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Article

Activated androgen receptor accelerates angiogenesis in cutaneous neurofibroma by regulating VEGFA transcription

Jing Jia, Haibao Zhang, Hongke Zhang, Huicong Du, Wenbo Liu, Maoguo Shu
Pages: 157-166
Published online on: 06 May 2019

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Article

Epigenetic modulators hydralazine and sodium valproate act synergistically in VEGI-mediated anti-angiogenesis and VEGF interference in human osteosarcoma and vascular endothelial cells

Shunsuke Kumanishi, Koji Yamanegi, Hiroshi Nishiura, Yuki Fujihara, Kenta Kobayashi, Keiji Nakasho, Hiroyuki Futani, Shinichi Yoshiya
Pages: 167-178
Published online on: 23 May 2019

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Article

Epithelial ovarian cancer stem‑like cells are resistant to the cellular lysis of cytokine‑induced killer cells via HIF1A‑mediated downregulation of ICAM‑1

Shixia Bu, Boning Li, Qian Wang, Tingting Gu, Qianggang Dong, Xiaofei Miao, Dongmei Lai
Pages: 179-190
Published online on: 03 May 2019

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Article

The XIAP inhibitor embelin sensitises malignant rhabdoid tumour cells to TRAIL treatment via enhanced activation of the extrinsic apoptotic pathway

Rachel Coyle, Karen Slattery, Leanne Ennis, Maureen J. O'sullivan, Daniela M. Zisterer
Pages: 191-202
Published online on: 20 May 2019

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Article

Inhibition of JAK2/STAT3 and activation of caspase‑9/3 are involved in KYS05090S‑induced apoptosis in ovarian cancer cells

Bo‑Im Kim, Ju‑Ha Kim, Deok Yong Sim, Minho Nam, Ji Hoon Jung, Bumsang Shim, Jaeyeol Lee, Sung‑Hoon Kim
Pages: 203-210
Published online on: 03 May 2019

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Article

S100P regulates the collective invasion of pancreatic cancer cells into the lymphatic endothelial monolayer

Hiromichi Nakayama, Kenoki Ohuchida, Akiko Yonenaga, Akiko Sagara, Yohei Ando, Shin Kibe, Shin Takesue, Toshiya Abe, Sho Endo, Kazuhiro Koikawa, Takashi Okumura, Koji Shido, Kei Miyoshi, Kohei Nakata, Taiki Moriyama, Yoshihiro Miyasaka, Shigetaka Inoue, Takao Ohtsuka, Kazuhiro Mizumoto, Masafumi Nakamura
Pages: 211-222
Published online on: 24 May 2019

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Article

Effects of 5-FU and anti-EGFR antibody in combination with ASA on the spherical culture system of HCT116 and HT29 colorectal cancer cell lines

Agata Olejniczak-Kęder, Magdalena Szaryńska, Agata Wrońska, Kamila Siedlecka-Kroplewska, Zbigniew Kmieć
Pages: 223-242
Published online on: 23 May 2019

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Article Open Access

Establishment and characterization of a novel cell line (cc‑006cpm8) of moderately/poorly differentiated colorectal adenocarcinoma derived from a primary tumor of a patient

Xia Chu, Yiqi Xue, Xinying Huo, Jingsun Wei, Yuetong Chen, Rongbo Han, Hong Chen, Xinyu Su, Honghong Zhang, Yang Gong, Jinfei Chen
Pages: 243-256
Published online on: 21 May 2019

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Article

CENPE promotes lung adenocarcinoma proliferation and is directly regulated by FOXM1 Corrigendum in /10.3892/ijo.2019.4872

Lina Shan, Minjie Zhao, Ya Lu, Hongjuan Ning, Shuman Yang, Yonggui Song, Wenshu Chai, Xianbao Shi
Pages: 257-266
Published online on: 20 May 2019

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Article

Transforming growth factor‑β/miR‑143‑3p/cystatin B axis is a therapeutic target in human ovarian cancer

Wencai Guan, Xingxing Wang, Qunbo Lin, Jinguo Zhang, Weimin Ren, Guoxiong Xu
Pages: 267-276
Published online on: 28 May 2019

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Article

USP39 promotes ovarian cancer malignant phenotypes and carboplatin chemoresistance

Lingzhi Wang, Tanxiu Chen, Xukun Li, Wei Yan, Yanhui Lou, Zhihua Liu, Hongyan Chen, Zhumei Cui
Pages: 277-288
Published online on: 29 May 2019

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Article

PF‑114, a novel selective inhibitor of BCR‑ABL tyrosine kinase, is a potent inducer of apoptosis in chronic myelogenous leukemia cells

Ekaterina S. Ivanova, Victor V. Tatarskiy, Margarita A. Yastrebova, Alvina I. Khamidullina, Alexei V. Shunaev, Anastasia A. Kalinina, Alexei A. Zeifman, Fedor N. Novikov, Yulia V. Dutikova, Ghermes G. Chilov, Alexander A. Shtil
Pages: 289-297
Published online on: 14 May 2019

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Article

Leptin stimulates the epithelial‑mesenchymal transition and pro‑angiogenic capability of cholangiocarcinoma cells through the miR‑122/PKM2 axis

Chuang Peng, Zengpeng Sun, Ou Li, Chao Guo, Weimin Yi, Zhaoxia Tan, Bo Jiang
Pages: 298-308
Published online on: 21 May 2019

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Article

Potent and specific fusion toxins consisting of a HER2‑binding, ABD‑derived affinity protein, fused to truncated versions of Pseudomonas exotoxin A

Hao Liu, Sarah Lindbo, Haozhong Ding, Mohamed Altai, Javad Garousi, Anna Orlova, Vladimir Tolmachev, Sophia Hober, Torbjörn Gräslund
Pages: 309-319
Published online on: 28 May 2019

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Article

Suppression of EGFR/STAT3 activity by lupeol contributes to the induction of the apoptosis of human non‑small cell lung cancer cells

Tae‑Rin Min, Hyun‑Ji Park, Ki‑Tae Ha, Gyoo‑Yong Chi, Yung‑Hyun Choi, Shin‑Hyung Park
Pages: 320-330
Published online on: 07 May 2019

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Article

Metformin induces TPC-1 cell apoptosis through endoplasmic reticulum stress-associated pathways in vitro and in vivo

Jianwen Ye, Lei Qi, Kunlun Chen, Renfeng Li, Shengping Song, Chuang Zhou, Wenlong Zhai
Pages: 331-339
Published online on: 31 May 2019

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Correction Open Access

[Corrigendum] Overexpression of lncRNA EGFR‑AS1 is associated with a poor prognosis and promotes chemotherapy resistance in non‑small cell lung cancer

Yu-Hua Xu, Jian-Ren Tu, Tian-Tian Zhao, Shi-Guang Xie, Sheng-Bo Tang
Pages: 340-340
Published online on: 14 January 2019

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Targeted therapies for urothelial carcinoma: From FGFR inhibitors to next‑generation antibody-drug conjugates (Review)

Jinping Du, Hao Shen, Tongwei Zeng, Wei Liu, Yongqiang Xie
Article Number: 28
Published online on: 22 December 2025

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Expression of Concern Open Access

[Expression of Concern] Establishment and evaluation of a new highly metastatic tumor cell line 5a‑D‑Luc‑ZsGreen expressing both luciferase and green fluorescent protein

Hitomi Sudo, Atsushi B. Tsuji, Aya Sugyo, Hiroyuki Takuwa, Kazuto Masamoto, Yutaka Tomita, Norihiro Suzuki, Takeshi Imamura, Mitsuru Koizumi, Tsuneo Saga
Article Number: 27
Published online on: 17 December 2025

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Review Open Access

Exosomal circRNAs in hepatocellular carcinoma: Implications for the development and therapeutic resistance of hepatocellular carcinoma (Review)

Zhiyao Liu, Yuqiao Wang, Yali Wang, Yucheng Zhang
Article Number: 26
Published online on: 16 December 2025

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Review Open Access

Advancements on the synergistic application of oncolytic viruses and molecularly targeted therapies for the treatment of solid tumors (Review)

Shiwen Bi, Tiyan Shan, Yong Tang, Qi Wang
Article Number: 25
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] Epigenetic high regulation of ATAD2 regulates the Hh pathway in human hepatocellular carcinoma

Gang Wu, Xiaojun Lu, Yawei Wang, Hui He, Xiangyu Meng, Shuguan Xia, Kunming Zhen, Yongfeng Liu
Article Number: 24
Published online on: 16 December 2025

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Review

CCDC137: A key hub for RNA and epigenetic regulation in cancer research (Review)

Xiaoying Zhao, Wenjing Zhang, Xiang Yu, Xiaohan Zhao, Xu Dai, Sirui Chen, Yan Wang, Jiang Cheng, Weiwei Zheng
Article Number: 23
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] Characterization of side population cells isolated from the colon cancer cell line SW480

Binghong Xiong, Li Ma, Xiang Hu, Caiquan Zhang, Yong Cheng
Article Number: 22
Published online on: 10 December 2025

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Review Open Access

mTOR in radiotherapy of lung cancer: Mechanisms of radiation resistance and therapeutic implications (Review)

Xiao Pang, Huai Liu, Ying Long, Hui Wang
Article Number: 21
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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Journal Cover
March-2026 Volume 68 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Suppression of the death gene BIK is a critical factor for resistance to tamoxifen in MCF‑7 breast cancer cells

Rubí Viedma-Rodriguez, Luis Arturo Baiza-Gutman, Alejandro García-Carrancá, Leticia Moreno-Fierros, Fabio Salamanca-Gómez, Diego Arenas-Aranda
Article Number: 29
Published online on: 23 December 2025

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