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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-April 2009 Volume 2 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Copy number variation and susceptibility to human disorders (Review)

Barkur S. Shastry
Pages: 143-147
Published online on: 01 March 2009

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Article

Site-specific induction of intestinal hypoxia-inducible factor-1α after hemorrhagic shock

Hiroyuki Nishie, Toru Takahashi, Kazuyoshi Inoue, Hiroko Shimizu, Hiroshi Morimatsu, Yuichiro Toda, Emiko Omori, Reiko Akagi, Hiroshi Katayama, Kiyoshi Morita
Pages: 149-152
Published online on: 01 March 2009

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Article

MEK1 gene mutation in Japanese lung adenocarcinoma patients

Hidefumi Sasaki, Yu Hikosaka, Katsuhiro Okuda, Osamu Kawano, Haruhiro Yukiue, Motoki Yano, Yoshitaka Fujii
Pages: 153-155
Published online on: 01 March 2009

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Positive emotion-specific changes in the gene expression profile of tickled rats

Miyo Hori, Takashi Hayashi, Yoshimi Nakagawa, Shigeko Sakamoto, Osamu Urayama, Kazuo Murakami
Pages: 157-161
Published online on: 01 March 2009

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Article

Expression of cysteinylLT1 receptor in human testicular cancer and growth reduction by its antagonist through apoptosis

Masahide Matsuyama, Kiyoaki Funao, Yutaka Kawahito, Hajime Sano, Jamel Chargui, Jean-Louis Touraine, Tatsuya Nakatani, Rikio Yoshimura
Pages: 163-167
Published online on: 01 March 2009

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Article

Expression of cytoplasmic p16 and anion exchanger 1 is associated with the invasion and absence of lymph metastasis in gastric carcinoma

Qiang Liu, Ling-Jun Song, Wei-Qing Xu, Lei Zhao, Lin Zheng, Zhao-Wen Yan, Guo-Hui Fu
Pages: 169-174
Published online on: 01 March 2009

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Article

Raman spectral signatures of human liver perfusates correlate with oxidation reduction potential

Raphael Bar-Or, Leonard T. Rael, C. Gerald Curtis, Charles W. Mains, Denetta S. Slone, David Bar-Or
Pages: 175-180
Published online on: 01 March 2009

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Article

Activation of the PI3K-AKT pathway in human malignant mesothelioma cells

Yutaro Suzuki, Hideki Murakami, Koji Kawaguchi, Tetsuo Tanigushi, Makiko Fujii, Keiko Shinjo, Yutaka Kondo, Hirotaka Osada, Kaoru Shimokata, Yoshitsugu Horio, Yoshinori Hasegawa, Toyoaki Hida, Yoshitaka Sekido
Pages: 181-188
Published online on: 01 March 2009

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Article

Direct effects of CPT-11 and SN38 on ovarian granulosa cells

Tomoko Utsunomiya, Tetsuji Tanaka, Hirotoshi Utsunomiya, Naohiko Umesaki
Pages: 189-192
Published online on: 01 March 2009

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Article

Telmisartan as a peroxisome proliferator-activated receptor-γ ligand is a new target in the treatment of human renal cell carcinoma

Kiyoaki Funao, Masahide Matsuyama, Yutaka Kawahito, Hajime Sano, Jamel Chargui, Jean-Louis Touraine, Tatsuya Nakatani, Rikio Yoshimura
Pages: 193-198
Published online on: 01 March 2009

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Mitochondrial depolarization and apoptosis associated with sustained activation of c-jun-N-terminal kinasein the human multiple myeloma cell line U266 induced by 2-aminophenoxazine-3-one

Akira Takasaki, Haruo Hanyu, Toshihiko Iwamoto, Ken Shirato, Ryutaro Izumi, Hiroko Toyota, Junichiro Mizuguchi, Keisuke Miyazawa, Akio Tomoda
Pages: 199-203
Published online on: 01 March 2009

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Association of polymorphisms of THBS2 and HSPA8 with hypertension in Japanese individuals with chronic kidney disease

Mitsutoshi Oguri, Kimihiko Kato, Kiyoshi Yokoi, Sachiro Watanabe, Norifumi Metoki, Hidemi Yoshida, Kei Satoh, Yukitoshi Aoyagi, Yutaka Nishigaki, Hideyo Yoshida, Yoshinori Nozawa, Yoshiji Yamada
Pages: 205-211
Published online on: 01 March 2009

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Article

Biphasic effect of short-term pregnancy hormone treatment on N-methyl-N-nitrosourea-induced mammary carcinogenesis in young and old rats

Yen-Chang Lai, Takashi Yuri, Norihisa Uehara, Yoichiro Matsuoka, Sayaka Kanematsu, Airo Tsubura
Pages: 213-220
Published online on: 01 March 2009

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Article

Euphorbiae humifusae induces apoptosis in Hep3B hepatocarcinoma cells via simultaneous activation of the death receptor-mediated and mitochondrial pathways

Sang Ho Seo, Dong Yeok Shin, Su Hyun Hong, Sang Eun Park, Yung Hyun Choi, Sang Hoon Hong
Pages: 221-227
Published online on: 01 March 2009

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Article

Mechanical stress up-regulates RANKL expression via the VEGF autocrine pathway in osteoblastic MC3T3-E1 cells

Takeshi Nakai, Yoshitaka Yoshimura, Yoshiaki Deyama, Kuniaki Suzuki, Junichiro Iida
Pages: 229-234
Published online on: 01 March 2009

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Article

MicroRNA-21 induces cell proliferation and invasion in esophageal squamous cell carcinoma

Yoichiro Mori, Hideyuki Ishiguro, Yoshiyuki Kuwabara, Masahiro Kimura, Akira Mitsui, Ryo Ogawa, Takeyasu Katada, Koshiro Harata, Tatsuya Tanaka, Midori Shiozaki, Yoshitaka Fujii
Pages: 235-239
Published online on: 01 March 2009

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Article

Down-regulation of HOXA4, HOXA7, HOXA10, HOXA11 and MEIS1 during monocyte-macrophage differentiation in THP-1 cells

Vincenzo Martino, Annalisa Bianchera, Laura Reia, Ovidio Bussolati, Raffaella Fazzina, Flora Marino, Luca Montemurro, Roberto Tonelli, Andrea Pession, Gian Carlo Gazzola, Roberto Sala
Pages: 241-244
Published online on: 01 March 2009

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Diallyl trisulfide reverses drug resistance and lowers the ratio of CD133+ cells in conjunction with methotrexate in a human osteosarcoma drug-resistant cell subline

Ji Li, Wei Liu, Kongbo Zhao, Yongkui Zhang, Xin Li, Qiang Yang, Zhenfeng Li, Jianmin Li
Pages: 245-252
Published online on: 01 March 2009

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Article

Increased concentration of plasminogen activator inhibitor-1 and fibrinogen in individuals with metabolic syndrome

Iván G. Palomo, César L. Gutiérrez, Marcelo L. Alarcón, Julio C. Jaramillo, Fabián M. Segovia, Elba M. Leiva, Verónica E. Mujica, Gloria N. Icaza, Nora S. Díaz, Rodrigo Moore-Carrasco
Pages: 253-257
Published online on: 01 March 2009

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Article

Genotype <21CAs/≥21CAs and allele <21CAs of the MANBA gene in melanoma risk and progression in a Swedish population

H. Bu, I. Rosdahl, X.-F. Sun, H. Zhang
Pages: 259-263
Published online on: 01 March 2009

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Article

Is the RET proto-oncogene involved in the pathogenesis of intestinal neuronal dysplasia type B?

Raquel María Fernández, Avencia Sánchez-Mejías, Maria Macarena Ruiz-Ferrer, Manuel López-Alonso, Guillermo Antiñolo, Salud Borrego
Pages: 265-270
Published online on: 01 March 2009

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Article

Betulinic acid does not modulate the activity of P-gp/ABCB1 or MRP1/ABCC1 in a non-tumoral renal cell line: Possible utility in multidrug resistance cancer chemotherapy

João Marcos Delou, Márcia Alves Marques Capella, Cerli Rocha Gattass
Pages: 271-275
Published online on: 01 March 2009

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Article

Common variants of the TLR9 gene influence the clinical course of HBV infection

Nina Jia, Qing Xie, Lanyi Lin, Honglian Gui, Hui Wang, Shan Jiang, Hong Yu, Qing Guo
Pages: 277-281
Published online on: 01 March 2009

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Article

Effect of the methylenetetrahydrofolate reductase gene C677T polymorphism on C-erbB-2 methylation status and its association with cancer

Zhonggan Jin, Qing Lu, Danhong Ge, Ming Zong, Qinghui Zhu
Pages: 283-289
Published online on: 01 March 2009

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Article

MUC1, MUC2 and MUC5AC expression in hepatocellular carcinoma with cardiac metastasis

Yu-Sheng Lin, Shih-Ming Jung, Chun-Nan Yeh, Yung-Chang Chen, Feng-Chun Tsai, Tzu-Fang Shiu, Hsueh-Hua Wu, Pyng-Jing Lin, Pao-Hsien Chu
Pages: 291-294
Published online on: 01 March 2009

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Article

Leptin promotes the immune escape of lung cancer by inducing proinflammatory cytokines and resistance to apoptosis

Yihong Shen, Qing Wang, Qiong Zhao, Jianying Zhou
Pages: 295-299
Published online on: 01 March 2009

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Article

Inhibitory effects of chemically modified heparin on the P-selectin-mediated adhesion of breast cancer cells in vitro

Donghui Mi, Yanguang Gao, Sheng Zheng, Xueqing Ba, Xianlu Zeng
Pages: 301-306
Published online on: 01 March 2009

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Article

Anti-apoptotic effects of pan-caspase inhibitor (Z-VAD), SOD or catalase on antimycin A-induced HeLa cell death

Yong Hwan Han, Suhn Hee Kim, Sung Zoo Kim, Woo Hyun Park
Pages: 307-311
Published online on: 01 March 2009

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Article

Pim-1 activation of cell motility induces the malignant phenotype of tongue carcinoma

Souichi Tanaka, Tetsuya Kitamura, Fumihiro Higashino, Kyoko Hida, Yoichi Ohiro, Mitsunobu Ono, Masanobu Kobayashi, Yasunori Totsuka, Masanobu Shindoh
Pages: 313-318
Published online on: 01 March 2009

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Article

Radiotherapy-induced decreases in substance P levels may potentiate melanoma growth

Aylin Fidan Korcum, Salih Sanlioglu, Gamze Aksu, Nina Tuncel, Nuray Erin
Pages: 319-326
Published online on: 01 March 2009

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Article

Clinical relevance of heparanase mRNA expression in bladder cancer and its usefulness as a detection marker in voided urine

Wei Zhao, Xin-Sheng Wang, Hai-Tao Niu, Li-Li Wang, Bang-Min Han, Shu-Jie Xia
Pages: 327-331
Published online on: 01 March 2009

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Journal Cover
April-2026 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Prostate‑specific membrane antigen: Molecular functions and emerging roles as a therapeutic target (Review)

Ryuta Watanabe, Tomohisa Sakaue, Noriyoshi Miura, Tadahiko Kikugawa, Takashi Saika
Article Number: 122
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑486‑5p inhibits the growth of human hypertrophic scar fibroblasts by regulating Smad2 expression

Yingying Shi, Luping Wang, Pijun Yu, Yi Liu, Wei Chen
Article Number: 121
Published online on: 25 February 2026

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Prenatal lipopolysaccharide exposure programs cardiac fibrosis via dysregulating of connexin 43 in offspring rats

Yan Wen, Yao Yuan, Haigang Zhang, Ya Liu
Article Number: 120
Published online on: 24 February 2026

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Retraction Open Access

[Retracted] Upregulated microRNA‑671‑3p promotes tumor progression by suppressing forkhead box P2 expression in non‑small‑cell lung cancer

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 119
Published online on: 16 February 2026

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Article Open Access

STAT1 accelerates cutaneous melanoma progression through TUBB4A expression regulation

Rongxin Zhao, Kexin Fang, Xiaofei Zhang, Hongchao Li
Article Number: 118
Published online on: 13 February 2026

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Review Open Access

Research progress on long non‑coding RNAs in lung cancer (Review)

Renjie Pan, Chaohui Wang, Yan Tang, Fengzhou Zhong, Yan Zhuang, Qiuxia Zhao
Article Number: 117
Published online on: 12 February 2026

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Article Open Access

ULK1 activates NCOA4‑mediated ferritinophagy via the Beclin1/VPS34 complex in cardiomyocyte hypertrophy

Qianhui Zhang, Meitian Zhang, Yongsheng Liu, Pilong Shi, Hanping Qi, Man Jiang, Yonggang Cao, Hongli Sun
Article Number: 116
Published online on: 12 February 2026

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Article Open Access

miRNA‑29a inhibits the proliferation of HUVECs by regulating the ITGB1/β‑catenin/c‑Myc pathway

Qi Sun, Wenting Chen, Shan Zhang, Xinni Zhong, Yafen Wu, Yingying Qian, Lei Zhu, Ting Zhang, Wei Li
Article Number: 115
Published online on: 12 February 2026

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Article Open Access

Puerarin attenuates myocardial ischemia‑reperfusion injury by inhibiting myocardium pyroptosis via the NRF2/HO‑1 signaling pathway

Xiaoyu Zheng, Jinping Li, Tianyang Hu, Li Tan, Ding Lan, Ying Deng
Article Number: 114
Published online on: 11 February 2026

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Review Open Access

Epigenetic crossroads in intervertebral disc degeneration: Unlocking novel therapeutic avenues (Review)

Yang Hou, Lei Liu, Yongfei Guo, Jiangang Shi
Article Number: 113
Published online on: 11 February 2026

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Retraction Open Access

[Retracted] miRNA‑30a‑3p inhibits metastasis and enhances radiosensitivity in esophageal carcinoma by targeting insulin‑like growth factor 1 receptor

Yanxin Fan, Xiuhua Bian, Pudong Qian, Jing Wen, Pengwei Yan, Yanhong Luo, Jing Wu, Qian Zhang
Article Number: 112
Published online on: 09 February 2026

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Review Open Access

Circular RNAs in intervertebral disc degeneration: Current insights into mechanisms and therapeutic potentials (Review)

Luyan Wang, Ke Yang, Houjun Zhu, Dachuan Wang, Feng Wang, Xianfa Du
Article Number: 111
Published online on: 05 February 2026

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Review Open Access

T‑cadherin and its impact on human diseases (Review)

Yan Song, Xinyi Wang, Yunfei Bian
Article Number: 110
Published online on: 05 February 2026

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Review

CD20 monoclonal antibody‑rituximab for the treatment of diffuse alveolar hemorrhage in children (Review)

Xiaobo Zhang, Xiao Wu, Yan Li, Guangmin Nong
Article Number: 109
Published online on: 05 February 2026

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Article Open Access

N6‑methyladenosine reader insulin‑like growth factor 2 mRNA‑binding protein 2 promotes abnormal proliferation of colonic epithelial cells in type 2 diabetes mellitus by regulating midkine

Jieyao Li, Qingsheng Xie, Jihao Xu
Article Number: 108
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin‑induced VEGF expression

Goutam Chakraborty, Shalini Jain, Smita Kale, Remya Raja, Santosh Kumar, Rosalin Mishra, Gopal C. Kundu
Article Number: 107
Published online on: 04 February 2026

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Review Open Access

Research status and molecular mechanisms of disulfidptosis in cardiovascular diseases (Review)

Xiao Jin, Zelin Cheng, Xinyue Ding, Zongjun Liu
Article Number: 106
Published online on: 03 February 2026

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Article Open Access

Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats

Caifen Guo, Jian Li
Article Number: 105
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 104
Published online on: 02 February 2026

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Article Open Access

Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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Journal Cover
May-2026 Volume 33 Issue 5

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Expression of Concern Open Access

[Expression of Concern] Dexmedetomidine protects against sepsis‑associated encephalopathy through Hsp90/AKT signaling

Lijun Yin, Xuejun Chen, Hongbo Ji, Shunli Gao
Article Number: 133
Published online on: 11 March 2026

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Glucose‑driven TRIB3 enhances the tumorigenic potential of colon cancer via the PI3K/AKT pathway

Yunting Bai, Xuying Huang, Guangyu An, Yang Ge, Rui Yan, Dan Yu
Article Number: 132
Published online on: 10 March 2026

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Retraction Open Access

[Retracted] miR‑222 regulates brain injury and inflammation following intracerebral hemorrhage by targeting ITGB8

Yan-Yan Bai, Jun-Zhi Niu
Article Number: 131
Published online on: 09 March 2026

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Dexmedetomidine protects against myocardial ischemia reperfusion injury by inhibiting the TLR2‑NF‑κB pathway in diabetic mice

Zhengjie Chen, Liangyu Zheng, Gang Chen
Article Number: 130
Published online on: 06 March 2026

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Long non‑coding RNA NKILA regulates the JAK2/STAT3 pathway to exacerbate TGF‑β1‑mediated renal fibrosis

Yu Han, Siqi Yang, Jing Zhang, Yaoguang Wang, Xi Zhao, Huan Liu
Article Number: 129
Published online on: 05 March 2026

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Retraction Open Access

[Retracted] Combination of HSP90 and autophagy inhibitors promotes hepatocellular carcinoma apoptosis following incomplete thermal ablation

Fen Chen, Haiyang Xie, Haiwei Bao, Laurencia Violetta, Shusen Zheng
Article Number: 128
Published online on: 05 March 2026

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Review Open Access

Advances regarding physiological functions and mechanisms of theaflavin‑3,3'‑digallate (Review)

Teng Ma, Siwei Zhang, Miaomiao Xiao, Zhijian Ma, Junhong Guan
Article Number: 127
Published online on: 04 March 2026

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Review Open Access

Mechanisms and therapeutic potential of glycyrrhizic acid: Insights into key signaling pathways and disease modulation (Review)

Jinjin Yu, Huiheng Qu, Weicheng Xu, Yiming Fang, Nan Wang, Wei Shi
Article Number: 126
Published online on: 04 March 2026

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Pyroptosis in cerebral ischemia‑reperfusion injury: Molecular mechanisms and therapeutic implications (Review)

Ze Li, Qiuli Ming, Tianyu Yang, Mengna Liu, Linpeng Fu, Jingshuang Yang, Zhaofeng Lu
Article Number: 125
Published online on: 04 March 2026

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Characteristics of chromosomal instability‑related lncRNAs associated with progression and prognosis in breast cancer

Qi Chen, Hui Chen, Hui Yang, Yin Tao, Xiaolan Zhu
Article Number: 124
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Associations between Huwe1 and autophagy in rat cerebral neuron oxygen‑glucose deprivation and reperfusion injury 

Guo-Qian He, Yan Chen, Hui-Juan Liao, Wen-Ming Xu, Wei Zhang, Guo-Lin He
Article Number: 123
Published online on: 26 February 2026

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