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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-June 2009 Volume 2 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

Correlation of the plasma level of insulin-like growth factor-1 with the number of aberrant crypt foci in male individuals

Hirokazu Takahashi, Tetsuji Takayama, Kunihiro Hosono, Kyoko Yoneda, Hiroki Endo, Yuichi Nozaki, Koji Fujita, Masato Yoneda, Masahiko Inamori, Yasunobu Abe, Noritoshi Kobayashi, Hiroyuki Kirikoshi, Kensuke Kubota, Satoru Saito, Hitoshi Nakagama, Atsushi Nakajima
Pages: 339-343
Published online on: 01 May 2009

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Article

Extracellular matrix metabolism-related gene expression in bile duct-ligated rats

Takaaki Sugihara, Masahiko Koda, Tomomitsu Matono, Kazunori Maeda, Satoru Yamamoto, Masaru Ueki, Yoshikazu Murawaki
Pages: 345-351
Published online on: 01 May 2009

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Article

Reduced expression of catenin subtypes is a potential indicator of unfavorable prognosis in esophageal squamous cell carcinoma

Tadahiro Nozoe, Tsunehiro Oyama, Hidetaka Uramoto, Mistuhiro Takenoyama, Takeshi Hanagiri, Kenji Sugio, Kosei Yasumoto
Pages: 353-357
Published online on: 01 May 2009

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Article Open Access

IL-1β stimulates IL-8 production, including prostaglandin E2 receptor EP4-triggered pathways, in synoviocyte MH7A cells

Yasuko Shibata, Hideo Kasai, Masaaki Shimada, Tohru Koitabashi, Toshiaki Arai, Rika Sai, Hiroko Terao, Masafumi Horikiri, Hideyuki Negishi, Keiji Miyazawa, Yoshimitsu Abiko
Pages: 359-363
Published online on: 01 May 2009

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Article

Genome-wide gene expression profiles of ovarian carcinoma: Identification of molecular targets for the treatment of ovarian carcinoma

Dragomira Nikolaeva Nikolova, Nikolai Doganov, Rumen Dimitrov, Krasimir Angelov, Siew-Kee Low, Ivanka Dimova, Draga Toncheva, Yusuke Nakamura, Hitoshi Zembutsu
Pages: 365-384
Published online on: 01 May 2009

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Article

Localization and characterization of γ-glutamyl cyclotransferase in cancer cells

Kaoru Azumi, Youhei Ikeda, Tomoharu Takeuchi, Tsuyoshi Nomura, Sorin V. Sabau, Jun-Ichi Hamada, Futoshi Okada, Masuo Hosokawa, Hideyoshi Yokosawa
Pages: 385-391
Published online on: 01 May 2009

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Article Open Access

Oral fluoropyrimidine S-1 combined with leucovorin is a promising therapy for colorectal cancer: Evidence from a xenograft model of folate-depleted mice

Sayaka Tsukioka, Junji Uchida, Hiroaki Tsujimoto, Fumio Nakagawa, Yoshikazu Sugimoto, Toshinori Oka, Mamoru Kiniwa
Pages: 393-398
Published online on: 01 May 2009

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Article

In vivo targeted killing of prostate tumor cells by a synthetic amoebapore helix 3 peptide modified with two γ-linked glutamate residues at the COOH terminus

Lori Holle, Wen Song, Eric Holle, Jennifer Nilsson, Yangzhang Wei, Jinhua Li, Thomas E. Wagner, Xianzhong Yu
Pages: 399-403
Published online on: 01 May 2009

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Article

Evaluation of the individual 50% inhibitory area under the concentration curve of 5-fluorouracil based on the collagen gel droplet embedded culture drug sensitivity test in colorectal cancer

Takumi Ochiai, Kazuhiko Nishimura, Tomoo Watanabe, Masayuki Kitajima, Masataka Tsuji, Akinori Nakatani, Noboru Nakayama, Takashi Marusasa, Satomi Mashiko, Isao Nagaoka, Shunji Futagawa
Pages: 405-409
Published online on: 01 May 2009

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Article

Combining anti-tumor drugs with mild hyperthermia increases the cytotoxic effects of drugs on human leukemia cells in vitro

Youko Itoh, Yoshiaki Kazaoka, Masakazu Nitta, Yoshiaki Yamada, Nobuaki Honda
Pages: 411-415
Published online on: 01 May 2009

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Article

Salvage therapy with temozolomide for recurrent or progressive high-grade gliomas refractory to ACNU [1-(4-amino-2-methyl-5-pyrimidynyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride]

Mizuhiko Terasaki, Takashi Tokutomi, Minoru Shigemori
Pages: 417-421
Published online on: 01 May 2009

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Article

A potential novel combination therapy targeting survivin in renal cancer cells: Inhibition of survivin expression by topotecan and hexamethylene bisacetamide

Akinori Sato, Takako Asano, Keichi Ito, Makoto Sumitomo, Tomohiko Asano, Masamichi Hayakawa
Pages: 423-428
Published online on: 01 May 2009

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Article

High dietary protein intake induces endothelial dysfunction in uninephrectomized rats

Tamehachi Namikoshi, Naruya Tomita, Minoru Satoh, Takeo Sakuta, Atsunori Kuwabara, Hajime Nagasu, Daisuke Yorimitsu, Tamaki Sasaki, Naoki Kashihara
Pages: 429-434
Published online on: 01 May 2009

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Article

Analysis of VEGF polymorphisms, tumor expression of VEGF mRNA and colorectal cancer susceptibility in a Swedish population

Jonas Ungerbäck, Nils Elander, Jan Dimberg, Peter Söderkvist
Pages: 435-439
Published online on: 01 May 2009

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Article

Effect of estradiol, progesterone and testosterone on apoptosis- and proliferation-induced MAPK signaling in human umbilical vein endothelial cells

Yanina Powazniak, Ana Catalina Kempfer, María de la Paz Dominguez, Cristina Farias, Leticia Keller, Julio Cesar Calderazzo, Maria Angela Lazzari
Pages: 441-447
Published online on: 01 May 2009

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Article

Comparative analysis of proliferative and genetic alterations in a primary chordoid meningioma and its recurrence using locus-specific probes and AgNOR

Ana Patrícia Barros Cordeiro, Fábio P.E. da Silva, Julio Cesar Pieczarka, Cleusa Yoshiko Nagamachi, Nilson Praia Anselmo, José Reginaldo Brito, Douglas S. Vasconcelos, Thomas Liehr, Anja Weise, Edivaldo H.C. de Oliveira
Pages: 449-454
Published online on: 01 May 2009

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Article

Secondary resistance to imatinib in patients with gastrointestinal stromal tumors through an acquired KIT exon 17 mutation

C. M. Wang, H. Fu, G. F. Zhao, X. Y. Zhou, C. Y. Du, R. Z. Dong, Y. Zhou, Y. Q. Shi
Pages: 455-460
Published online on: 01 May 2009

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Article

Hepatitis C virus F protein: A double-edged sword in the potential contribution of chronic inflammation to carcinogenesis

Jing Kong, Xiaozhao Deng, Zhongchan Wang, Jingjing Yang, Yun Zhang, Juan Yu
Pages: 461-469
Published online on: 01 May 2009

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Article

Blockade of NF-κB activation by IκBα gene therapy enhances radiation sensitivity and abolishes acquired resistance to radiation

Choon-Taek Lee, Mi Young Park, Dal Rae Kim, Eun Kyung Choi, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Young-Soo Shim, Yeon-Soo Kim
Pages: 471-475
Published online on: 01 May 2009

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Article

Titration of serum CEA, p53 antibodies and CEA-IgM complexes in patients with colorectal cancer

Taiki Kojima, Kazuhiro Yoshikawa, Takanori Matsui, Yasuhiro Kodera, Hiroshi Kojima
Pages: 477-480
Published online on: 01 May 2009

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Article

Increased concentrations of soluble vascular cell adhesion molecule-1 and soluble CD40L in subjects with metabolic syndrome

Iván G. Palomo, Julio C. Jaramillo, Marcelo L. Alarcón, César L. Gutiérrez, Rodrigo Moore-Carrasco, Fabián M. Segovia, Elba M. Leiva, Verónica E. Mujica, Gloria Icaza, Nora S. Dí
Pages: 481-485
Published online on: 01 May 2009

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Article

Induction of resistance to murine tumor development is associated with alterations in the glycosylation of blood serum proteins

F. V. Donenko, R. K. Ziganshin, S. M. Sitdikova, B. S. Amandzholov, M. V. Kiselevskii, T. Efferth
Pages: 487-495
Published online on: 01 May 2009

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Article

Effect of butyrate on the heregulin/ErbB-mediated proliferation of human colorectal cancer cells

Soo-Jeong Lim, Moon-Kyung Choi, Min Jung Kim, Chang-Hun Lee
Pages: 497-502
Published online on: 01 May 2009

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Article

Tumor-enhancing activity of Basigin expression in gallbladder carcinoma and its prognostic role

Guang-Fa Xiao, Hui-Huan Tang
Pages: 503-508
Published online on: 01 May 2009

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Article

Hesperetin inhibits the maturation and function of monocyte-derived dendritic cells from patients with asthma

Xiaouan Gu, Linfu Zhou, Qiang Du, Desheng Jiang, Xiaofan Yang, Xiaohui Ji, Kaisheng Yin
Pages: 509-513
Published online on: 01 May 2009

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Article

Antitumor efficacy of human telomerase reverse transcriptase gene antisense oligonucleotide in pancreatic cancer cells

Yongping Liu, Yang Ling, Yuedi Hu, Yingze Kong, Peng Li, Zhiwu Zhou, Baorui Liu
Pages: 515-521
Published online on: 01 May 2009

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Journal Cover
May-2026 Volume 33 Issue 5

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Identification of STMN1 as a lactylation‑related driver of lung cancer progression using Mendelian randomization

Yifan Cai, Yucheng Zhong, Honglin Wang, Shuang Zhu, Fang Huang, Qiuyue Zhang, Shaobo Hu
Article Number: 156
Published online on: 30 March 2026

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Review Open Access

Advances in the mechanisms of extracellular vesicles and circulating tumor cells in hepatocellular carcinoma metastasis (Review)

Sitong Yi, Wenxin Liu, Zhaohui Wang
Article Number: 155
Published online on: 30 March 2026

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Article Open Access

Diagnostic importance of serum markers in lung cancer

Qichen Liang, Jianmei Song, Haixiang Wei, Lu Ning, Baoyu He, Ziteng Zhang
Article Number: 154
Published online on: 30 March 2026

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VSNL1 attenuates hypoxia‑induced myocardial apoptosis by regulating the CNP/NPRB pathway

Xing Yang, Wenjuan Fang, Rui Chang, Linlin Ma, Xiaoyan Chen, Yanfei Li
Article Number: 153
Published online on: 30 March 2026

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Review Open Access

Stabilin‑1: An immunoregulatory scavenger receptor in inflammation and tissue homeostasis (Review)

Xiao-Lei Xiang, Xin-Tong Ye, Yu-Tong Wu, Chen Chen, Chu-Ying Yu, Su-Ting Qian, Dan-Li Cai
Article Number: 152
Published online on: 26 March 2026

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Mechanism and therapeutic prospects of adipose tissue B lymphocytes in obesity and obesity‑associated metabolic diseases (Review)

Hong Wang, Hongyuan Lv, Xiaolin Zhang, Meifang Liu, Liyuan Wang
Article Number: 151
Published online on: 26 March 2026

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Tonsil‑derived mesenchymal stem cell‑derived extracellular vesicles suppress MAPK‑NF‑κB signaling and restore osteogenic differentiation in LPS‑stimulated periodontal ligament fibroblasts

Won-Jung Bae, Su Kang Kim, Han-Soo Kim, Sang Wook Kang, Ju Yeon Ban
Article Number: 150
Published online on: 26 March 2026

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Succinylation modification in diabetes and diabetic complications: Mechanisms and functions (Review)

Yeteng Xiong, Fei Luo, Bingnan Li, Qinfeng Yang
Article Number: 149
Published online on: 26 March 2026

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Polyphyllin II regulates ROS levels and promotes ferroptosis in bladder cancer cells

Quanlai Qiao, Ruifang Guo, Zhonghua Sun, Yaxin Shi, Yuning Xie, Zhiyong Liu
Article Number: 148
Published online on: 26 March 2026

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Veronicastrum sibiricum (L.) Pennell extract alleviates inflammation‑induced muscle atrophy through NLRP3 inflammasome regulation and mitochondrial function restoration

Eunhye Lee, Minjeong Kwon, Ju-Ock Nam
Article Number: 147
Published online on: 26 March 2026

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Role and clinical importance of lactylation in tumors (Review)

Chaowei Zhang, Xinyu Tang, Yuxuan Han, Weiyi Yao, Qing Hong, Yanan Zhu, Na Chen
Article Number: 146
Published online on: 26 March 2026

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Photodynamic therapy: A paradigm shift in overcoming drug‑resistant tuberculosis (Review)

Shuhao Cheng, Yuqing Wang, Jie Yao, Guodong Cheng, Gengzhi Ye, Fapeng Shi, Xiaolei Ma
Article Number: 145
Published online on: 26 March 2026

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Heterogeneous nuclear ribonucleoprotein K in cancer biology and its therapeutic applications (Review)

Yiyu Qin, Yang Zhou
Article Number: 144
Published online on: 26 March 2026

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Retraction Open Access

[Retracted] Na+/K+‑ATPase DR region‑specific antibody protects U251 cells against hypoxia reperfusion‑induced injury via the PI3K/AKT and ERK pathways

Huilin Gong, Pengbiao Lü, Jiangwei Zhang, Dandong Li, Jin Zheng, Jinning Song
Article Number: 143
Published online on: 23 March 2026

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Multi‑omics and their integration in psoriasis research (Review)

Hengyan Zhang, Danping Li, Lijuan Zhu, Heguo Yan, Licong Yang, Xuesong Yang, Ye Zhou
Article Number: 142
Published online on: 23 March 2026

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Article Open Access

LDHA protects vascular endothelial cells from oxidative stress‑induced mitochondrial damage via HIF‑1α activation and glycolytic reprogramming

Beibei Dai, Lili Yang, Yu Zhang, Aiyong Yu
Article Number: 141
Published online on: 23 March 2026

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Article

Mechanism of BRCC36 affecting cardiac rupture after acute infarction through the Wnt‑JNK signaling pathway

Yongzhe Guo, Linyan Chen, Shumei Li, Xintao Zhang, Huizhong Lin
Article Number: 140
Published online on: 20 March 2026

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Correction Open Access

[Corrigendum] Puerarin alleviates the ototoxicity of gentamicin by inhibiting the mitochondria‑dependent apoptosis pathway

Ping Niu, Yuxuan Sun, Shiyi Wang, Guang Li, Xiaomin Tang, Jiaqiang Sun, Chunchen Pan, Jingwu Sun
Article Number: 139
Published online on: 19 March 2026

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Role of liver X receptors in the pathogenesis and treatment of chronic liver disease (Review)

Honghui You, Xiangjun Tang, Xiaoyan Fu, Jiaqi Zhou, Liyuan Wang, Hongxia Zhang, Xianhong Du, Shujuan Liang, Meifang Liu
Article Number: 138
Published online on: 19 March 2026

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Mechanistic insights and therapeutic potential of sphingosine‑1‑phosphate in the development of pulmonary fibrosis (Review)

Yanling Qin, Chenqi Tang, Sen Tan, Guangnan Liu
Article Number: 137
Published online on: 18 March 2026

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Review Open Access

Advances in the biological functions of miR‑205 in various diseases (Review)

Dandan Chai, Hua Du, Yingxu Shi
Article Number: 136
Published online on: 18 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑25‑3p regulates human nucleus pulposus cell proliferation and apoptosis in intervertebral disc degeneration by targeting Bim

Zhifang Zhao, Jie Zheng, Youchen Ye, Kefeng Zhao, Ruozhang Wang, Ran Wang
Article Number: 135
Published online on: 16 March 2026

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Article Open Access

Precision medicine approach to coronary artery disease: Haptoglobin phenotype‑guided risk assessment

Zhengxin He, Hong Liu, Keran Jia, Daxin Lei, Liyun An, Jia Wang, Fukun Wang
Article Number: 134
Published online on: 12 March 2026

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Expression of Concern Open Access

[Expression of Concern] Dexmedetomidine protects against sepsis‑associated encephalopathy through Hsp90/AKT signaling

Lijun Yin, Xuejun Chen, Hongbo Ji, Shunli Gao
Article Number: 133
Published online on: 11 March 2026

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Article Open Access

Glucose‑driven TRIB3 enhances the tumorigenic potential of colon cancer via the PI3K/AKT pathway

Yunting Bai, Xuying Huang, Guangyu An, Yang Ge, Rui Yan, Dan Yu
Article Number: 132
Published online on: 10 March 2026

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Retraction Open Access

[Retracted] miR‑222 regulates brain injury and inflammation following intracerebral hemorrhage by targeting ITGB8

Yan-Yan Bai, Jun-Zhi Niu
Article Number: 131
Published online on: 09 March 2026

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Dexmedetomidine protects against myocardial ischemia reperfusion injury by inhibiting the TLR2‑NF‑κB pathway in diabetic mice

Zhengjie Chen, Liangyu Zheng, Gang Chen
Article Number: 130
Published online on: 06 March 2026

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Article Open Access

Long non‑coding RNA NKILA regulates the JAK2/STAT3 pathway to exacerbate TGF‑β1‑mediated renal fibrosis

Yu Han, Siqi Yang, Jing Zhang, Yaoguang Wang, Xi Zhao, Huan Liu
Article Number: 129
Published online on: 05 March 2026

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Retraction Open Access

[Retracted] Combination of HSP90 and autophagy inhibitors promotes hepatocellular carcinoma apoptosis following incomplete thermal ablation

Fen Chen, Haiyang Xie, Haiwei Bao, Laurencia Violetta, Shusen Zheng
Article Number: 128
Published online on: 05 March 2026

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Review Open Access

Advances regarding physiological functions and mechanisms of theaflavin‑3,3'‑digallate (Review)

Teng Ma, Siwei Zhang, Miaomiao Xiao, Zhijian Ma, Junhong Guan
Article Number: 127
Published online on: 04 March 2026

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Mechanisms and therapeutic potential of glycyrrhizic acid: Insights into key signaling pathways and disease modulation (Review)

Jinjin Yu, Huiheng Qu, Weicheng Xu, Yiming Fang, Nan Wang, Wei Shi
Article Number: 126
Published online on: 04 March 2026

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Pyroptosis in cerebral ischemia‑reperfusion injury: Molecular mechanisms and therapeutic implications (Review)

Ze Li, Qiuli Ming, Tianyu Yang, Mengna Liu, Linpeng Fu, Jingshuang Yang, Zhaofeng Lu
Article Number: 125
Published online on: 04 March 2026

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Characteristics of chromosomal instability‑related lncRNAs associated with progression and prognosis in breast cancer

Qi Chen, Hui Chen, Hui Yang, Yin Tao, Xiaolan Zhu
Article Number: 124
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Associations between Huwe1 and autophagy in rat cerebral neuron oxygen‑glucose deprivation and reperfusion injury 

Guo-Qian He, Yan Chen, Hui-Juan Liao, Wen-Ming Xu, Wei Zhang, Guo-Lin He
Article Number: 123
Published online on: 26 February 2026

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Journal Cover
June-2026 Volume 33 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Current research progress on extracellular vesicles derived from mesenchymal stem cells in tuberculosis treatment (Review)

Dejun Fan, Yan Yang, Li Yang
Article Number: 163
Published online on: 01 April 2026

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Article Open Access

Uremic toxin p‑cresyl sulfate enhances the calcification of aortic valvular interstitial cells via klotho/sirtuin‑1 signaling

Shao-Jung Li, Tzu-Yu Cheng, Yu-Hsun Kao, Wei-Yu Chen, Cheng-Chih Chung, Nguyen Ngoc Trang, Pao-Huan Chen, Yi-Jen Chen
Article Number: 162
Published online on: 01 April 2026

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Review Open Access

Exercise‑induced extracellular vesicle microRNA regulates physiological function (Review)

Zhonglei Wang, Wenjue Guo, Haojia He, Yi Zhang, Na Li
Article Number: 161
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 160
Published online on: 01 April 2026

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Article Open Access

Emerging roles of POLR2L of RNA polymerase II dynamics and disease mechanisms (Review)

Beomwoo Lee, Changgyu Son, Sunho Eom, Yuwen Li, Seon-Hwan Kim, Jongsun Park
Article Number: 159
Published online on: 30 March 2026

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Article Open Access

Combining bioinformatics prediction with experimental validation to explore the ameliorative effect of Psoralea corylifolia on vitiligo

Chen Zhang, Zhanhong Cao, Mengyang Wei, Xuanxuan Zhu, Yan Yan, Zhenhua Wang, Meng Zhang
Article Number: 158
Published online on: 30 March 2026

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Retraction Open Access

[Retracted] All‑trans‑retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud mesenchymal cells by down­regulating p53 expression

Tao-Gen Zhang, Xue-Dong Li, Guo-Yong Yu, Peng Xie, Yun-Guo Wang, Zhao-Yong Liu, Quan Hong, De-Zhong Liu, Shi-Xin Du
Article Number: 157
Published online on: 30 March 2026

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