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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-June 2009 Volume 2 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

Correlation of the plasma level of insulin-like growth factor-1 with the number of aberrant crypt foci in male individuals

Hirokazu Takahashi, Tetsuji Takayama, Kunihiro Hosono, Kyoko Yoneda, Hiroki Endo, Yuichi Nozaki, Koji Fujita, Masato Yoneda, Masahiko Inamori, Yasunobu Abe, Noritoshi Kobayashi, Hiroyuki Kirikoshi, Kensuke Kubota, Satoru Saito, Hitoshi Nakagama, Atsushi Nakajima
Pages: 339-343
Published online on: 01 May 2009

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Article

Extracellular matrix metabolism-related gene expression in bile duct-ligated rats

Takaaki Sugihara, Masahiko Koda, Tomomitsu Matono, Kazunori Maeda, Satoru Yamamoto, Masaru Ueki, Yoshikazu Murawaki
Pages: 345-351
Published online on: 01 May 2009

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Article

Reduced expression of catenin subtypes is a potential indicator of unfavorable prognosis in esophageal squamous cell carcinoma

Tadahiro Nozoe, Tsunehiro Oyama, Hidetaka Uramoto, Mistuhiro Takenoyama, Takeshi Hanagiri, Kenji Sugio, Kosei Yasumoto
Pages: 353-357
Published online on: 01 May 2009

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Article Open Access

IL-1β stimulates IL-8 production, including prostaglandin E2 receptor EP4-triggered pathways, in synoviocyte MH7A cells

Yasuko Shibata, Hideo Kasai, Masaaki Shimada, Tohru Koitabashi, Toshiaki Arai, Rika Sai, Hiroko Terao, Masafumi Horikiri, Hideyuki Negishi, Keiji Miyazawa, Yoshimitsu Abiko
Pages: 359-363
Published online on: 01 May 2009

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Article

Genome-wide gene expression profiles of ovarian carcinoma: Identification of molecular targets for the treatment of ovarian carcinoma

Dragomira Nikolaeva Nikolova, Nikolai Doganov, Rumen Dimitrov, Krasimir Angelov, Siew-Kee Low, Ivanka Dimova, Draga Toncheva, Yusuke Nakamura, Hitoshi Zembutsu
Pages: 365-384
Published online on: 01 May 2009

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Article

Localization and characterization of γ-glutamyl cyclotransferase in cancer cells

Kaoru Azumi, Youhei Ikeda, Tomoharu Takeuchi, Tsuyoshi Nomura, Sorin V. Sabau, Jun-Ichi Hamada, Futoshi Okada, Masuo Hosokawa, Hideyoshi Yokosawa
Pages: 385-391
Published online on: 01 May 2009

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Article Open Access

Oral fluoropyrimidine S-1 combined with leucovorin is a promising therapy for colorectal cancer: Evidence from a xenograft model of folate-depleted mice

Sayaka Tsukioka, Junji Uchida, Hiroaki Tsujimoto, Fumio Nakagawa, Yoshikazu Sugimoto, Toshinori Oka, Mamoru Kiniwa
Pages: 393-398
Published online on: 01 May 2009

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Article

In vivo targeted killing of prostate tumor cells by a synthetic amoebapore helix 3 peptide modified with two γ-linked glutamate residues at the COOH terminus

Lori Holle, Wen Song, Eric Holle, Jennifer Nilsson, Yangzhang Wei, Jinhua Li, Thomas E. Wagner, Xianzhong Yu
Pages: 399-403
Published online on: 01 May 2009

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Article

Evaluation of the individual 50% inhibitory area under the concentration curve of 5-fluorouracil based on the collagen gel droplet embedded culture drug sensitivity test in colorectal cancer

Takumi Ochiai, Kazuhiko Nishimura, Tomoo Watanabe, Masayuki Kitajima, Masataka Tsuji, Akinori Nakatani, Noboru Nakayama, Takashi Marusasa, Satomi Mashiko, Isao Nagaoka, Shunji Futagawa
Pages: 405-409
Published online on: 01 May 2009

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Article

Combining anti-tumor drugs with mild hyperthermia increases the cytotoxic effects of drugs on human leukemia cells in vitro

Youko Itoh, Yoshiaki Kazaoka, Masakazu Nitta, Yoshiaki Yamada, Nobuaki Honda
Pages: 411-415
Published online on: 01 May 2009

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Article

Salvage therapy with temozolomide for recurrent or progressive high-grade gliomas refractory to ACNU [1-(4-amino-2-methyl-5-pyrimidynyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride]

Mizuhiko Terasaki, Takashi Tokutomi, Minoru Shigemori
Pages: 417-421
Published online on: 01 May 2009

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Article

A potential novel combination therapy targeting survivin in renal cancer cells: Inhibition of survivin expression by topotecan and hexamethylene bisacetamide

Akinori Sato, Takako Asano, Keichi Ito, Makoto Sumitomo, Tomohiko Asano, Masamichi Hayakawa
Pages: 423-428
Published online on: 01 May 2009

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Article

High dietary protein intake induces endothelial dysfunction in uninephrectomized rats

Tamehachi Namikoshi, Naruya Tomita, Minoru Satoh, Takeo Sakuta, Atsunori Kuwabara, Hajime Nagasu, Daisuke Yorimitsu, Tamaki Sasaki, Naoki Kashihara
Pages: 429-434
Published online on: 01 May 2009

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Article

Analysis of VEGF polymorphisms, tumor expression of VEGF mRNA and colorectal cancer susceptibility in a Swedish population

Jonas Ungerbäck, Nils Elander, Jan Dimberg, Peter Söderkvist
Pages: 435-439
Published online on: 01 May 2009

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Article

Effect of estradiol, progesterone and testosterone on apoptosis- and proliferation-induced MAPK signaling in human umbilical vein endothelial cells

Yanina Powazniak, Ana Catalina Kempfer, María de la Paz Dominguez, Cristina Farias, Leticia Keller, Julio Cesar Calderazzo, Maria Angela Lazzari
Pages: 441-447
Published online on: 01 May 2009

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Article

Comparative analysis of proliferative and genetic alterations in a primary chordoid meningioma and its recurrence using locus-specific probes and AgNOR

Ana Patrícia Barros Cordeiro, Fábio P.E. da Silva, Julio Cesar Pieczarka, Cleusa Yoshiko Nagamachi, Nilson Praia Anselmo, José Reginaldo Brito, Douglas S. Vasconcelos, Thomas Liehr, Anja Weise, Edivaldo H.C. de Oliveira
Pages: 449-454
Published online on: 01 May 2009

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Article

Secondary resistance to imatinib in patients with gastrointestinal stromal tumors through an acquired KIT exon 17 mutation

C. M. Wang, H. Fu, G. F. Zhao, X. Y. Zhou, C. Y. Du, R. Z. Dong, Y. Zhou, Y. Q. Shi
Pages: 455-460
Published online on: 01 May 2009

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Article

Hepatitis C virus F protein: A double-edged sword in the potential contribution of chronic inflammation to carcinogenesis

Jing Kong, Xiaozhao Deng, Zhongchan Wang, Jingjing Yang, Yun Zhang, Juan Yu
Pages: 461-469
Published online on: 01 May 2009

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Article

Blockade of NF-κB activation by IκBα gene therapy enhances radiation sensitivity and abolishes acquired resistance to radiation

Choon-Taek Lee, Mi Young Park, Dal Rae Kim, Eun Kyung Choi, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Young-Soo Shim, Yeon-Soo Kim
Pages: 471-475
Published online on: 01 May 2009

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Article

Titration of serum CEA, p53 antibodies and CEA-IgM complexes in patients with colorectal cancer

Taiki Kojima, Kazuhiro Yoshikawa, Takanori Matsui, Yasuhiro Kodera, Hiroshi Kojima
Pages: 477-480
Published online on: 01 May 2009

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Article

Increased concentrations of soluble vascular cell adhesion molecule-1 and soluble CD40L in subjects with metabolic syndrome

Iván G. Palomo, Julio C. Jaramillo, Marcelo L. Alarcón, César L. Gutiérrez, Rodrigo Moore-Carrasco, Fabián M. Segovia, Elba M. Leiva, Verónica E. Mujica, Gloria Icaza, Nora S. Dí
Pages: 481-485
Published online on: 01 May 2009

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Article

Induction of resistance to murine tumor development is associated with alterations in the glycosylation of blood serum proteins

F. V. Donenko, R. K. Ziganshin, S. M. Sitdikova, B. S. Amandzholov, M. V. Kiselevskii, T. Efferth
Pages: 487-495
Published online on: 01 May 2009

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Article

Effect of butyrate on the heregulin/ErbB-mediated proliferation of human colorectal cancer cells

Soo-Jeong Lim, Moon-Kyung Choi, Min Jung Kim, Chang-Hun Lee
Pages: 497-502
Published online on: 01 May 2009

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Article

Tumor-enhancing activity of Basigin expression in gallbladder carcinoma and its prognostic role

Guang-Fa Xiao, Hui-Huan Tang
Pages: 503-508
Published online on: 01 May 2009

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Article

Hesperetin inhibits the maturation and function of monocyte-derived dendritic cells from patients with asthma

Xiaouan Gu, Linfu Zhou, Qiang Du, Desheng Jiang, Xiaofan Yang, Xiaohui Ji, Kaisheng Yin
Pages: 509-513
Published online on: 01 May 2009

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Article

Antitumor efficacy of human telomerase reverse transcriptase gene antisense oligonucleotide in pancreatic cancer cells

Yongping Liu, Yang Ling, Yuedi Hu, Yingze Kong, Peng Li, Zhiwu Zhou, Baorui Liu
Pages: 515-521
Published online on: 01 May 2009

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Journal Cover
September-2026 Volume 34 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Chronic kidney disease‑associated encephalopathy: Clinical features, pathomechanisms and emerging therapeutic strategies (Review)

Nanling Zeng, Ling Jiang, Yang Zhang, Jian Liu, Qiong Zhang, Lishang Liao, Qiongdan Hu
Article Number: 259
Published online on: 21 July 2026

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Retraction Open Access

[Retracted] Emodin promotes the arrest of human lymphoma Raji cell proliferation through the UHRF1‑DNMT3A‑∆Np73 pathways

Yun Lin, Weiming Chen, Zhihong Wang, Pengwei Cai
Article Number: 258
Published online on: 20 July 2026

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Article Open Access

Sedanolide alleviates LPS‑induced depressive‑like behaviors by modulating the C3a/C3aR signaling axis and microglial glycolysis

Shaocong Lu, Fangla Luo, Niqi Chen, Gongde Shi, Yeru Chen
Article Number: 257
Published online on: 16 July 2026

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Expression of Concern Open Access

[Expression of Concern] Chrysophanol inhibits proliferation and induces apoptosis through NF‑κB/cyclin D1 and NF‑κB/Bcl‑2 signaling cascade in breast cancer cell lines

Li Ren, Zhouping Li, Chunmei Dai, Danyu Zhao, Yanjie Wang, Chunyu Ma, Chun Liu
Article Number: 256
Published online on: 15 July 2026

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Article Open Access

PCSK9 alleviates doxorubicin‑induced pyroptosis of cardiomyocytes

Chaochu Cui, Jinyu Zhao, Xiaoqian Li, Shengming Huang, Gang Liu, Xinhui Xu, Can Guo, Tiesuo Zhao, Jiang Du, Shipeng Li, Xianwei Wang, Jianbo Yang
Article Number: 255
Published online on: 14 July 2026

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Review Open Access

From cell to disease: Regulatory networks and mechanisms of super‑enhancers in aging (Review)

Xiaodan Wang, Weiqian Deng, Shuangxi Tu, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 254
Published online on: 14 July 2026

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Retraction Open Access

[Retracted] Matrine‑induced apoptosis in Hep3B cells via the inhibition of MDM2

Ning Zhou, Jiequn Li, Ting Li, Guangshun Chen, Zhongqiang Zhang, Zhongzhou Si
Article Number: 253
Published online on: 13 July 2026

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Review Open Access

Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review)

Lan Wang, Zhiyuan Ma, Bei Ji, Shuhui Liu, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 252
Published online on: 09 July 2026

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Article

Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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Correction Open Access

[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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Review Open Access

A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
Published online on: 07 July 2026

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Review Open Access

Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Article Open Access

Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Review Open Access

Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Review Open Access

Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Article Open Access

Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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Review Open Access

TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Article Open Access

Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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Retraction Open Access

[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Article Open Access

Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Article Open Access

Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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Journal Cover
October-2026 Volume 34 Issue 4

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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