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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-June 2009 Volume 2 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

Correlation of the plasma level of insulin-like growth factor-1 with the number of aberrant crypt foci in male individuals

Hirokazu Takahashi, Tetsuji Takayama, Kunihiro Hosono, Kyoko Yoneda, Hiroki Endo, Yuichi Nozaki, Koji Fujita, Masato Yoneda, Masahiko Inamori, Yasunobu Abe, Noritoshi Kobayashi, Hiroyuki Kirikoshi, Kensuke Kubota, Satoru Saito, Hitoshi Nakagama, Atsushi Nakajima
Pages: 339-343
Published online on: 01 May 2009

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Article

Extracellular matrix metabolism-related gene expression in bile duct-ligated rats

Takaaki Sugihara, Masahiko Koda, Tomomitsu Matono, Kazunori Maeda, Satoru Yamamoto, Masaru Ueki, Yoshikazu Murawaki
Pages: 345-351
Published online on: 01 May 2009

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Article

Reduced expression of catenin subtypes is a potential indicator of unfavorable prognosis in esophageal squamous cell carcinoma

Tadahiro Nozoe, Tsunehiro Oyama, Hidetaka Uramoto, Mistuhiro Takenoyama, Takeshi Hanagiri, Kenji Sugio, Kosei Yasumoto
Pages: 353-357
Published online on: 01 May 2009

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Article Open Access

IL-1β stimulates IL-8 production, including prostaglandin E2 receptor EP4-triggered pathways, in synoviocyte MH7A cells

Yasuko Shibata, Hideo Kasai, Masaaki Shimada, Tohru Koitabashi, Toshiaki Arai, Rika Sai, Hiroko Terao, Masafumi Horikiri, Hideyuki Negishi, Keiji Miyazawa, Yoshimitsu Abiko
Pages: 359-363
Published online on: 01 May 2009

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Article

Genome-wide gene expression profiles of ovarian carcinoma: Identification of molecular targets for the treatment of ovarian carcinoma

Dragomira Nikolaeva Nikolova, Nikolai Doganov, Rumen Dimitrov, Krasimir Angelov, Siew-Kee Low, Ivanka Dimova, Draga Toncheva, Yusuke Nakamura, Hitoshi Zembutsu
Pages: 365-384
Published online on: 01 May 2009

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Article

Localization and characterization of γ-glutamyl cyclotransferase in cancer cells

Kaoru Azumi, Youhei Ikeda, Tomoharu Takeuchi, Tsuyoshi Nomura, Sorin V. Sabau, Jun-Ichi Hamada, Futoshi Okada, Masuo Hosokawa, Hideyoshi Yokosawa
Pages: 385-391
Published online on: 01 May 2009

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Article Open Access

Oral fluoropyrimidine S-1 combined with leucovorin is a promising therapy for colorectal cancer: Evidence from a xenograft model of folate-depleted mice

Sayaka Tsukioka, Junji Uchida, Hiroaki Tsujimoto, Fumio Nakagawa, Yoshikazu Sugimoto, Toshinori Oka, Mamoru Kiniwa
Pages: 393-398
Published online on: 01 May 2009

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Article

In vivo targeted killing of prostate tumor cells by a synthetic amoebapore helix 3 peptide modified with two γ-linked glutamate residues at the COOH terminus

Lori Holle, Wen Song, Eric Holle, Jennifer Nilsson, Yangzhang Wei, Jinhua Li, Thomas E. Wagner, Xianzhong Yu
Pages: 399-403
Published online on: 01 May 2009

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Article

Evaluation of the individual 50% inhibitory area under the concentration curve of 5-fluorouracil based on the collagen gel droplet embedded culture drug sensitivity test in colorectal cancer

Takumi Ochiai, Kazuhiko Nishimura, Tomoo Watanabe, Masayuki Kitajima, Masataka Tsuji, Akinori Nakatani, Noboru Nakayama, Takashi Marusasa, Satomi Mashiko, Isao Nagaoka, Shunji Futagawa
Pages: 405-409
Published online on: 01 May 2009

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Article

Combining anti-tumor drugs with mild hyperthermia increases the cytotoxic effects of drugs on human leukemia cells in vitro

Youko Itoh, Yoshiaki Kazaoka, Masakazu Nitta, Yoshiaki Yamada, Nobuaki Honda
Pages: 411-415
Published online on: 01 May 2009

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Article

Salvage therapy with temozolomide for recurrent or progressive high-grade gliomas refractory to ACNU [1-(4-amino-2-methyl-5-pyrimidynyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride]

Mizuhiko Terasaki, Takashi Tokutomi, Minoru Shigemori
Pages: 417-421
Published online on: 01 May 2009

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Article

A potential novel combination therapy targeting survivin in renal cancer cells: Inhibition of survivin expression by topotecan and hexamethylene bisacetamide

Akinori Sato, Takako Asano, Keichi Ito, Makoto Sumitomo, Tomohiko Asano, Masamichi Hayakawa
Pages: 423-428
Published online on: 01 May 2009

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Article

High dietary protein intake induces endothelial dysfunction in uninephrectomized rats

Tamehachi Namikoshi, Naruya Tomita, Minoru Satoh, Takeo Sakuta, Atsunori Kuwabara, Hajime Nagasu, Daisuke Yorimitsu, Tamaki Sasaki, Naoki Kashihara
Pages: 429-434
Published online on: 01 May 2009

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Article

Analysis of VEGF polymorphisms, tumor expression of VEGF mRNA and colorectal cancer susceptibility in a Swedish population

Jonas Ungerbäck, Nils Elander, Jan Dimberg, Peter Söderkvist
Pages: 435-439
Published online on: 01 May 2009

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Article

Effect of estradiol, progesterone and testosterone on apoptosis- and proliferation-induced MAPK signaling in human umbilical vein endothelial cells

Yanina Powazniak, Ana Catalina Kempfer, María de la Paz Dominguez, Cristina Farias, Leticia Keller, Julio Cesar Calderazzo, Maria Angela Lazzari
Pages: 441-447
Published online on: 01 May 2009

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Article

Comparative analysis of proliferative and genetic alterations in a primary chordoid meningioma and its recurrence using locus-specific probes and AgNOR

Ana Patrícia Barros Cordeiro, Fábio P.E. da Silva, Julio Cesar Pieczarka, Cleusa Yoshiko Nagamachi, Nilson Praia Anselmo, José Reginaldo Brito, Douglas S. Vasconcelos, Thomas Liehr, Anja Weise, Edivaldo H.C. de Oliveira
Pages: 449-454
Published online on: 01 May 2009

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Article

Secondary resistance to imatinib in patients with gastrointestinal stromal tumors through an acquired KIT exon 17 mutation

C. M. Wang, H. Fu, G. F. Zhao, X. Y. Zhou, C. Y. Du, R. Z. Dong, Y. Zhou, Y. Q. Shi
Pages: 455-460
Published online on: 01 May 2009

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Article

Hepatitis C virus F protein: A double-edged sword in the potential contribution of chronic inflammation to carcinogenesis

Jing Kong, Xiaozhao Deng, Zhongchan Wang, Jingjing Yang, Yun Zhang, Juan Yu
Pages: 461-469
Published online on: 01 May 2009

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Article

Blockade of NF-κB activation by IκBα gene therapy enhances radiation sensitivity and abolishes acquired resistance to radiation

Choon-Taek Lee, Mi Young Park, Dal Rae Kim, Eun Kyung Choi, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Young-Soo Shim, Yeon-Soo Kim
Pages: 471-475
Published online on: 01 May 2009

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Article

Titration of serum CEA, p53 antibodies and CEA-IgM complexes in patients with colorectal cancer

Taiki Kojima, Kazuhiro Yoshikawa, Takanori Matsui, Yasuhiro Kodera, Hiroshi Kojima
Pages: 477-480
Published online on: 01 May 2009

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Article

Increased concentrations of soluble vascular cell adhesion molecule-1 and soluble CD40L in subjects with metabolic syndrome

Iván G. Palomo, Julio C. Jaramillo, Marcelo L. Alarcón, César L. Gutiérrez, Rodrigo Moore-Carrasco, Fabián M. Segovia, Elba M. Leiva, Verónica E. Mujica, Gloria Icaza, Nora S. Dí
Pages: 481-485
Published online on: 01 May 2009

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Article

Induction of resistance to murine tumor development is associated with alterations in the glycosylation of blood serum proteins

F. V. Donenko, R. K. Ziganshin, S. M. Sitdikova, B. S. Amandzholov, M. V. Kiselevskii, T. Efferth
Pages: 487-495
Published online on: 01 May 2009

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Article

Effect of butyrate on the heregulin/ErbB-mediated proliferation of human colorectal cancer cells

Soo-Jeong Lim, Moon-Kyung Choi, Min Jung Kim, Chang-Hun Lee
Pages: 497-502
Published online on: 01 May 2009

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Article

Tumor-enhancing activity of Basigin expression in gallbladder carcinoma and its prognostic role

Guang-Fa Xiao, Hui-Huan Tang
Pages: 503-508
Published online on: 01 May 2009

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Article

Hesperetin inhibits the maturation and function of monocyte-derived dendritic cells from patients with asthma

Xiaouan Gu, Linfu Zhou, Qiang Du, Desheng Jiang, Xiaofan Yang, Xiaohui Ji, Kaisheng Yin
Pages: 509-513
Published online on: 01 May 2009

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Article

Antitumor efficacy of human telomerase reverse transcriptase gene antisense oligonucleotide in pancreatic cancer cells

Yongping Liu, Yang Ling, Yuedi Hu, Yingze Kong, Peng Li, Zhiwu Zhou, Baorui Liu
Pages: 515-521
Published online on: 01 May 2009

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

CTRP4 ameliorates dexamethasone‑induced insulin resistance through the IRS‑1/PI3K/AKT pathway in 3T3‑L1 adipocytes

Maireyanmu Rouzi, Xi Sun, Luguang Sheng, Bilin Xu, Tao Lei, Jun Lu, Jie Gao
Article Number: 101
Published online on: 27 January 2026

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Article Open Access

PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity

Hevna Dhulkifle, Lubna Therachiyil, Maram H. Hasan, Shahd M. Younis, Nizar A. Al‑Shar'i, Huseyin C. Yalcin, Zaid H. Maayah
Article Number: 100
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression

Jianwen Long, Jing Luo, Xuwen Yin
Article Number: 99
Published online on: 26 January 2026

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Review Open Access

Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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Article Open Access

HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Article Open Access

Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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Review

PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Article Open Access

Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Review Open Access

Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Article Open Access

Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Review Open Access

Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Article Open Access

Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Article Open Access

Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Article Open Access

Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Article Open Access

Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Review Open Access

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Review Open Access

Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Research status and molecular mechanisms of disulfidptosis in cardiovascular diseases (Review)

Xiao Jin, Zelin Cheng, Xinyue Ding, Zongjun Liu
Article Number: 106
Published online on: 03 February 2026

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Article Open Access

Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats

Caifen Guo, Jian Li
Article Number: 105
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 104
Published online on: 02 February 2026

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Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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