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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-April 2011 Volume 4 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Role of genetic polymorphisms and mutations in colorectal cancer therapy (Review)

Marco Aiello, Nadia Vella, Calogero Cannavò, Aurora Scalisi, Demetrios A. Spandidos, Giuseppe Toffoli, Angela Buonadonna, Massimo Libra, Franca Stivala
Pages: 203-208
Published online on: 16 December 2010

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Antibodies against swine influenza virus neutralize the pandemic influenza virus A/H1N1

Masaya Tsukamoto, Satoshi Hiroi, Kazuhide Adachi, Hidenori Kato, Marie Inai, Itsuro Konishi, Masaru Tanaka, Ryouhei Yamamoto, Masaki  Sawa, Ekowati Handharyani, Yasuhiro Tsukamoto
Pages: 209-214
Published online on: 03 January 2011

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Article

Estrogen receptor α induces down-regulation of PTEN through PI3-kinase activation in breast cancer cells

Eun-Mi Noh, Young-Rae Lee, Kee-Oh Chay, Eun-Yong Chung, Sung Hoo Jung, Jong-Suk Kim, Hyun Jo Youn
Pages: 215-219
Published online on: 03 January 2011

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Emodin potentiates the antitumor effects of gemcitabine in pancreatic cancer cells via inhibition of nuclear factor-κB

An Liu, Hui Chen, Hongfei Tong, Sheng Ye, Maixuan Qiu, Zhaohong Wang, Wei Tan, Jinxiang Liu, Shengzhang Lin
Pages: 221-227
Published online on: 03 January 2011

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Article

Skeletal muscle tissue from the Goto-Kakizaki rat model of type-2 diabetes exhibits increased levels of the small heat shock protein Hsp27

Edel Mullen, Elaine O’Reilly, Kay Ohlendieck
Pages: 229-236
Published online on: 25 January 2011

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Article

Novel IRF6 mutations in Honduran Van Der Woude syndrome patients

Andrew C. Birkeland, Yuna Larrabee, David T. Kent, Carlos  Flores, Gloria H. Su, Joseph H. Lee, Joseph Haddad
Pages: 237-241
Published online on: 11 January 2011

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Unbalanced MMP/TIMP-1 expression during the development of experimental pulmonary fibrosis with acute paraquat poisoning

Bo-Liang Wang, Yan-Yang Tu, Jian-Fang Fu, Yue-Xia Zhong, Guo‑Qiang Fu, Xiao-Xi Tian, Li-He Wang, Li Gong, Qin-You Ren
Pages: 243-248
Published online on: 14 January 2011

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Overexpression of angiotensin II type 2 receptor suppresses neointimal hyperplasia in a rat carotid arterial balloon injury model

Bing Tang, Shuangtao Ma, Yongjian Yang, Dachun Yang, Jinsong Chen, Xiaohua Su, Yan Tan, Meiqin Sun, De Li
Pages: 249-254
Published online on: 25 January 2011

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Change of telomere length in angiotensin ii-induced human glomerular mesangial cell senescence and the protective role of losartan

Xin Feng, Lining Wang, Yao Li
Pages: 255-260
Published online on: 25 January 2011

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Article

A novel adriamycin analogue derived from marine microbes induces apoptosis by blocking Akt activation in human breast cancer cells

Jie Yuan, Zhenjian He, Jueheng Wu, Yongcheng Lin, Xun Zhu
Pages: 261-265
Published online on: 25 January 2011

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Detection of human metapneumovirus in infants with acute respiratory tract infection

Ioannis N. Mammas, Chryssie Koutsaftiki, Elisabeth Nika, Fotini Vagia, Apostolos Zaravinos, Kostas N. Priftis, Aliki Voyatzi, Maria Theodoridou, Nikolaos Myriokefalitakis, Demetrios A. Spandidos
Pages: 267-271
Published online on: 03 January 2011

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Myricetin induces G2/M phase arrest in HepG2 cells by inhibiting the activity of the cyclin B/Cdc2 complex

Xiao-Hong Zhang, Zu-Quan Zou, Chen-Wei Xu, Ying-Zhuo Shen, Duo Li
Pages: 273-277
Published online on: 05 January 2011

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Three cases of Hb Q-H disease found in a Cantonese family

Chaohui Hu, Ling Zhang, Jianghu Pan, Zengyu Zeng, Saixiang Zhen, Ju Fang, Qingyi Zhu
Pages: 279-281
Published online on: 05 January 2011

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Interleukin-6 -634C>G polymorphism in hypertensive patients with and without left ventricular hypertrophy

Feng Chen, Jing Guo, Shu-Ping Gao, Chu Chen, Yun-Feng Guo, Le Gui, Hai-Hua Geng, Li-Jun Ge, Jian-Hua Zhu, Min Pan
Pages: 283-289
Published online on: 03 January 2011

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Activity of 5-HT1A receptor is involved in neuronal apoptosis of the amygdala in a rat model of post-traumatic stress disorder

Hong Liu, Hai-Tao Wang, Fang Han, Yu-Xiu Shi
Pages: 291-295
Published online on: 03 January 2011

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(-)-Epigallocatechin gallate inhibits thyroid hormone‑stimulated osteocalcin synthesis in osteoblasts

Kenji Kato, Takanobu Otsuka, Seiji Adachi, Rie Matsushima-Nishiwaki, Hideo Natsume, Osamu Kozawa, Haruhiko Tokuda
Pages: 297-300
Published online on: 11 January 2011

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Differentially expressed genes in Men1 knockout and wild‑type embryoid bodies for pancreatic islet development

Hong-Li Zhang, Wen-Yi Li, Cui-Ping Zhang, Ya-Xin Zhu, Ling Wu, Hong-Mei Long, Guo Li, Min Luo
Pages: 301-305
Published online on: 03 January 2011

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STAT3 enhances intracellular Fas-mediated apoptotic signals in HHUA human endometrial epithelial cells

Tetsuji Tanaka, Tao Bai, Hirotoshi Utsunomiya, Takahiro Fukumoto, Kazunori Yukawa
Pages: 307-312
Published online on: 12 January 2011

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Patrinia scabiosaefolia extract suppresses proliferation and promotes apoptosis by inhibiting the STAT3 pathway in human multiple myeloma cells

Jun Peng, Youqin Chen, Jiumao Lin, Qunchuan Zhuang, Wei Xu, Zhenfeng Hong, Thomas J. Sferra
Pages: 313-318
Published online on: 03 January 2011

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Progesterone inhibits inflammatory response pathways after permanent middle cerebral artery occlusion in rats

Jianping Wang, Yuanzheng Zhao, Chunling Liu, Chao Jiang, Chunyan Zhao, Zhongjun Zhu
Pages: 319-324
Published online on: 05 January 2011

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Sulforaphane blocks hypoxia-mediated resistance to TRAIL-induced tumor cell death

Jae-Kyo Jeong, Myung-Hee Moon, Jae-Suk Seo, Jae-Won Seol, You-Jin Lee, Sang-Youel Park
Pages: 325-330
Published online on: 11 January 2011

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Mutations of the Connexin 26 gene in families with non-syndromic hearing loss

Walid Al-Achkar, Faten Moassass, Bassel Al-Halabi, Ayman Al-Ablog
Pages: 331-335
Published online on: 25 January 2011

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Inhibitory effect of esculetin on migration, invasion and matrix metalloproteinase-9 expression in TNF-α-induced vascular smooth muscle cells

Se-Jung Lee, Ung-Soo Lee, Wun-Jae Kim, Sung-Kwon Moon
Pages: 337-341
Published online on: 05 January 2011

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Knockdown of c-Met inhibits cell proliferation and invasion and increases chemosensitivity to doxorubicin in human multiple myeloma U266 cells in vitro

Wenzhong Que, Junmin Chen
Pages: 343-349
Published online on: 14 January 2011

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Article

Preventive role of Propofol in hypoxia/reoxygenation‑induced apoptotic H9c2 rat cardiac myoblast cell death

Seonmin Lee, Kiyoon Kim, Yun Hong Kim, Min Hyung Chung, Insug Kang, Joohun Ha, Wonchae Choe
Pages: 351-356
Published online on: 25 January 2011

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Article

Gefitinib induces mitochondrial-dependent apoptosis in Saccharomyces cerevisiae

Jing Wu, Rou Min, Minchen Wu, Wei Chen
Pages: 357-362
Published online on: 18 January 2011

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Article

Chondroitin synthases I, II, III and chondroitin sulfate glucuronyltransferase expression in colorectal cancer

Dimitrios Kalathas, Dimitrios A. Theocharis, Dimitrios Bounias, Dora Kyriakopoulou, Nikoletta Papageorgakopoulou, Michael S. Stavropoulos, Demitrios H. Vynios
Pages: 363-368
Published online on: 25 January 2011

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Article

IL-10 expression is regulated by HPV E2 protein in cervical cancer cells

V. H. Bermúdez-Morales, O. Peralta-Zaragoza, J. M. Alcocer‑González, J. Moreno, V. Madrid-Marina
Pages: 369-375
Published online on: 25 January 2011

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Expression of β-catenin and cyclin D1 in epidermal stem cells of diabetic rats

Qing-Ling Zhong, Fan-Rong Liu, De-Wu Liu, Yan Peng, Xiang-Rong Zhang
Pages: 377-381
Published online on: 25 January 2011

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Aberrant expression of let-7a miRNA in the blood of non-small cell lung cancer patients

Hye Cheol Jeong, Eun Kyung Kim, Ji Hyun Lee, Han Na Yoo, Jin Kyeoung Kim
Pages: 383-387
Published online on: 25 January 2011

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Journal Cover
May-2026 Volume 33 Issue 5

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Identification of STMN1 as a lactylation‑related driver of lung cancer progression using Mendelian randomization

Yifan Cai, Yucheng Zhong, Honglin Wang, Shuang Zhu, Fang Huang, Qiuyue Zhang, Shaobo Hu
Article Number: 156
Published online on: 30 March 2026

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Advances in the mechanisms of extracellular vesicles and circulating tumor cells in hepatocellular carcinoma metastasis (Review)

Sitong Yi, Wenxin Liu, Zhaohui Wang
Article Number: 155
Published online on: 30 March 2026

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Diagnostic importance of serum markers in lung cancer

Qichen Liang, Jianmei Song, Haixiang Wei, Lu Ning, Baoyu He, Ziteng Zhang
Article Number: 154
Published online on: 30 March 2026

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VSNL1 attenuates hypoxia‑induced myocardial apoptosis by regulating the CNP/NPRB pathway

Xing Yang, Wenjuan Fang, Rui Chang, Linlin Ma, Xiaoyan Chen, Yanfei Li
Article Number: 153
Published online on: 30 March 2026

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Stabilin‑1: An immunoregulatory scavenger receptor in inflammation and tissue homeostasis (Review)

Xiao-Lei Xiang, Xin-Tong Ye, Yu-Tong Wu, Chen Chen, Chu-Ying Yu, Su-Ting Qian, Dan-Li Cai
Article Number: 152
Published online on: 26 March 2026

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Mechanism and therapeutic prospects of adipose tissue B lymphocytes in obesity and obesity‑associated metabolic diseases (Review)

Hong Wang, Hongyuan Lv, Xiaolin Zhang, Meifang Liu, Liyuan Wang
Article Number: 151
Published online on: 26 March 2026

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Tonsil‑derived mesenchymal stem cell‑derived extracellular vesicles suppress MAPK‑NF‑κB signaling and restore osteogenic differentiation in LPS‑stimulated periodontal ligament fibroblasts

Won-Jung Bae, Su Kang Kim, Han-Soo Kim, Sang Wook Kang, Ju Yeon Ban
Article Number: 150
Published online on: 26 March 2026

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Succinylation modification in diabetes and diabetic complications: Mechanisms and functions (Review)

Yeteng Xiong, Fei Luo, Bingnan Li, Qinfeng Yang
Article Number: 149
Published online on: 26 March 2026

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Polyphyllin II regulates ROS levels and promotes ferroptosis in bladder cancer cells

Quanlai Qiao, Ruifang Guo, Zhonghua Sun, Yaxin Shi, Yuning Xie, Zhiyong Liu
Article Number: 148
Published online on: 26 March 2026

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Veronicastrum sibiricum (L.) Pennell extract alleviates inflammation‑induced muscle atrophy through NLRP3 inflammasome regulation and mitochondrial function restoration

Eunhye Lee, Minjeong Kwon, Ju-Ock Nam
Article Number: 147
Published online on: 26 March 2026

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Role and clinical importance of lactylation in tumors (Review)

Chaowei Zhang, Xinyu Tang, Yuxuan Han, Weiyi Yao, Qing Hong, Yanan Zhu, Na Chen
Article Number: 146
Published online on: 26 March 2026

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Photodynamic therapy: A paradigm shift in overcoming drug‑resistant tuberculosis (Review)

Shuhao Cheng, Yuqing Wang, Jie Yao, Guodong Cheng, Gengzhi Ye, Fapeng Shi, Xiaolei Ma
Article Number: 145
Published online on: 26 March 2026

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Heterogeneous nuclear ribonucleoprotein K in cancer biology and its therapeutic applications (Review)

Yiyu Qin, Yang Zhou
Article Number: 144
Published online on: 26 March 2026

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Retraction Open Access

[Retracted] Na+/K+‑ATPase DR region‑specific antibody protects U251 cells against hypoxia reperfusion‑induced injury via the PI3K/AKT and ERK pathways

Huilin Gong, Pengbiao Lü, Jiangwei Zhang, Dandong Li, Jin Zheng, Jinning Song
Article Number: 143
Published online on: 23 March 2026

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Multi‑omics and their integration in psoriasis research (Review)

Hengyan Zhang, Danping Li, Lijuan Zhu, Heguo Yan, Licong Yang, Xuesong Yang, Ye Zhou
Article Number: 142
Published online on: 23 March 2026

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LDHA protects vascular endothelial cells from oxidative stress‑induced mitochondrial damage via HIF‑1α activation and glycolytic reprogramming

Beibei Dai, Lili Yang, Yu Zhang, Aiyong Yu
Article Number: 141
Published online on: 23 March 2026

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Article

Mechanism of BRCC36 affecting cardiac rupture after acute infarction through the Wnt‑JNK signaling pathway

Yongzhe Guo, Linyan Chen, Shumei Li, Xintao Zhang, Huizhong Lin
Article Number: 140
Published online on: 20 March 2026

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Correction Open Access

[Corrigendum] Puerarin alleviates the ototoxicity of gentamicin by inhibiting the mitochondria‑dependent apoptosis pathway

Ping Niu, Yuxuan Sun, Shiyi Wang, Guang Li, Xiaomin Tang, Jiaqiang Sun, Chunchen Pan, Jingwu Sun
Article Number: 139
Published online on: 19 March 2026

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Role of liver X receptors in the pathogenesis and treatment of chronic liver disease (Review)

Honghui You, Xiangjun Tang, Xiaoyan Fu, Jiaqi Zhou, Liyuan Wang, Hongxia Zhang, Xianhong Du, Shujuan Liang, Meifang Liu
Article Number: 138
Published online on: 19 March 2026

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Mechanistic insights and therapeutic potential of sphingosine‑1‑phosphate in the development of pulmonary fibrosis (Review)

Yanling Qin, Chenqi Tang, Sen Tan, Guangnan Liu
Article Number: 137
Published online on: 18 March 2026

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Review Open Access

Advances in the biological functions of miR‑205 in various diseases (Review)

Dandan Chai, Hua Du, Yingxu Shi
Article Number: 136
Published online on: 18 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑25‑3p regulates human nucleus pulposus cell proliferation and apoptosis in intervertebral disc degeneration by targeting Bim

Zhifang Zhao, Jie Zheng, Youchen Ye, Kefeng Zhao, Ruozhang Wang, Ran Wang
Article Number: 135
Published online on: 16 March 2026

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Precision medicine approach to coronary artery disease: Haptoglobin phenotype‑guided risk assessment

Zhengxin He, Hong Liu, Keran Jia, Daxin Lei, Liyun An, Jia Wang, Fukun Wang
Article Number: 134
Published online on: 12 March 2026

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Expression of Concern Open Access

[Expression of Concern] Dexmedetomidine protects against sepsis‑associated encephalopathy through Hsp90/AKT signaling

Lijun Yin, Xuejun Chen, Hongbo Ji, Shunli Gao
Article Number: 133
Published online on: 11 March 2026

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Glucose‑driven TRIB3 enhances the tumorigenic potential of colon cancer via the PI3K/AKT pathway

Yunting Bai, Xuying Huang, Guangyu An, Yang Ge, Rui Yan, Dan Yu
Article Number: 132
Published online on: 10 March 2026

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Retraction Open Access

[Retracted] miR‑222 regulates brain injury and inflammation following intracerebral hemorrhage by targeting ITGB8

Yan-Yan Bai, Jun-Zhi Niu
Article Number: 131
Published online on: 09 March 2026

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Dexmedetomidine protects against myocardial ischemia reperfusion injury by inhibiting the TLR2‑NF‑κB pathway in diabetic mice

Zhengjie Chen, Liangyu Zheng, Gang Chen
Article Number: 130
Published online on: 06 March 2026

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Long non‑coding RNA NKILA regulates the JAK2/STAT3 pathway to exacerbate TGF‑β1‑mediated renal fibrosis

Yu Han, Siqi Yang, Jing Zhang, Yaoguang Wang, Xi Zhao, Huan Liu
Article Number: 129
Published online on: 05 March 2026

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Retraction Open Access

[Retracted] Combination of HSP90 and autophagy inhibitors promotes hepatocellular carcinoma apoptosis following incomplete thermal ablation

Fen Chen, Haiyang Xie, Haiwei Bao, Laurencia Violetta, Shusen Zheng
Article Number: 128
Published online on: 05 March 2026

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Review Open Access

Advances regarding physiological functions and mechanisms of theaflavin‑3,3'‑digallate (Review)

Teng Ma, Siwei Zhang, Miaomiao Xiao, Zhijian Ma, Junhong Guan
Article Number: 127
Published online on: 04 March 2026

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Mechanisms and therapeutic potential of glycyrrhizic acid: Insights into key signaling pathways and disease modulation (Review)

Jinjin Yu, Huiheng Qu, Weicheng Xu, Yiming Fang, Nan Wang, Wei Shi
Article Number: 126
Published online on: 04 March 2026

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Pyroptosis in cerebral ischemia‑reperfusion injury: Molecular mechanisms and therapeutic implications (Review)

Ze Li, Qiuli Ming, Tianyu Yang, Mengna Liu, Linpeng Fu, Jingshuang Yang, Zhaofeng Lu
Article Number: 125
Published online on: 04 March 2026

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Characteristics of chromosomal instability‑related lncRNAs associated with progression and prognosis in breast cancer

Qi Chen, Hui Chen, Hui Yang, Yin Tao, Xiaolan Zhu
Article Number: 124
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Associations between Huwe1 and autophagy in rat cerebral neuron oxygen‑glucose deprivation and reperfusion injury 

Guo-Qian He, Yan Chen, Hui-Juan Liao, Wen-Ming Xu, Wei Zhang, Guo-Lin He
Article Number: 123
Published online on: 26 February 2026

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Journal Cover
June-2026 Volume 33 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Emerging roles of POLR2L of RNA polymerase II dynamics and disease mechanisms (Review)

Beomwoo Lee, Changgyu Son, Sunho Eom, Yuwen Li, Seon-Hwan Kim, Jongsun Park
Article Number: 159
Published online on: 30 March 2026

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Article Open Access

Combining bioinformatics prediction with experimental validation to explore the ameliorative effect of Psoralea corylifolia on vitiligo

Chen Zhang, Zhanhong Cao, Mengyang Wei, Xuanxuan Zhu, Yan Yan, Zhenhua Wang, Meng Zhang
Article Number: 158
Published online on: 30 March 2026

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Retraction Open Access

[Retracted] All‑trans‑retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud mesenchymal cells by down­regulating p53 expression

Tao-Gen Zhang, Xue-Dong Li, Guo-Yong Yu, Peng Xie, Yun-Guo Wang, Zhao-Yong Liu, Quan Hong, De-Zhong Liu, Shi-Xin Du
Article Number: 157
Published online on: 30 March 2026

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