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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2011 Volume 28 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Beyond neurological disease: New targets for edaravone (Review)

Kiyoshi Kikuchi, Hisaaki Uchikado, Naohisa Miyagi, Yoko Morimoto, Takashi Ito, Salunya Tancharoen, Naoki Miura, Kei Miyata, Rokudai Sakamoto, Chiemi Kikuchi, Narumi Iida, Naoto Shiomi, Terukazu Kuramoto, Ko-Ichi Kawahara
Pages: 899-906
Published online on: 15 September 2011

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Article

Impact of static magnetic fields on human myoblast cell cultures

Jens Stern-Straeter, Gabriel Alejandro Bonaterra, Stefan S. Kassner, Anne Faber, Alexander Sauter, Johannes D. Schulz, Karl Hörmann, Ralf Kinscherf, Ulrich Reinhart Goessler
Pages: 907-917
Published online on: 11 August 2011

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Article

Sodium valproate blocks the transforming growth factor (TGF)-β1 autocrine loop and attenuates the TGF-β1-induced collagen synthesis in a human hepatic stellate cell line

Toshifumi Watanabe, Hidehiro Tajima, Hayashi Hironori, Hisatoshi Nakagawara, Ichiro Ohnishi, Hiroyuki Takamura, Itasu Ninomiya, Hirohisa Kitagawa, Sachio Fushida, Takashi Tani, Takashi Fujimura, Tetsuo Ota, Tomohiko Wakayama, Shoichi Iseki, Shinichi Harada
Pages: 919-925
Published online on: 05 August 2011

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Article

Zanthoxylum avicennae extracts induce cell apoptosis through protein phosphatase 2A activation in HA22T human hepatocellular carcinoma cells and block tumor growth in xenografted nude mice

Tran Duc Dung, Hsien-Cheh Chang, Chung-Yu Chen, Wen-Huang Peng, Chang-Hai Tsai, Fuu-Jen Tsai, Wei-Wen Kuo, Li-Mien Chen, Chih-Yang Huang
Pages: 927-936
Published online on: 19 August 2011

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Article

Inhibitory effects of vitamin K3 derivatives on DNA polymerase and inflammatory activity

Aoganghua Aoganghua, Shin Nishiumi, Kazuki Kobayashi, Masayuki Nishida, Kouji Kuramochi, Kazunori Tsubaki, Midori Hirai, Shinwa Tanaka, Takeshi Azuma, Hiromi Yoshida, Yoshiyuki Mizushina, Masaru Yoshida
Pages: 937-945
Published online on: 11 August 2011

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Article

ECM-based triple layered scaffolds for vascular tissue engineering

Claudio Grandi, Francesca Martorina, Silvano Lora, Daniele Dalzoppo, Pietro Amistà, Leonardo Sartore, Rosa Di Liddo, Maria Teresa Conconi, Pier Paolo Parnigotto
Pages: 947-952
Published online on: 11 August 2011

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Article

Multidrug resistance-associated protein 3 and Bcl-2 contribute to multidrug resistance by vinorelbine in lung adenocarcinoma

Xuan Hong, Zhao-Yang Yang, Meng Wang, Lu Lu, Ying-Hong Li, Xishan Hao, Gong-Yan Chen
Pages: 953-960
Published online on: 19 August 2011

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Article

Pen-2 overexpression induces Aβ-42 production, memory defect, motor activity enhancement and feeding behavior dysfunction in NSE/Pen-2 transgenic mice

So Hee Nam, Su Jin Seo, Jun Seo Goo, Jee Eun Kim, Sun Il Choi, Hae Ryun Lee, In Sik Hwang, Seung Wan Jee, Su Hae Lee, Chang Jun Bae, Jung Youn Park, Hye Sung Kim, Sun Bo Shim, Dae Youn Hwang
Pages: 961-971
Published online on: 05 August 2011

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Article

KIF21A novel deletion and recurrent mutation in patients with congenital fibrosis of the extraocular muscles-1

Panfeng Wang, Shiqiang Li, Xueshan Xiao, Xiangming Guo, Qingjiong Zhang
Pages: 973-975
Published online on: 26 July 2011

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Article

HDAC inhibitor 4-phenylbutyrate preserves immature phenotype of human embryonic midbrain stem cells: Implications for the involvement of DNA methyltransferase

Zahidul Khan, Monira Akhtar, Tomas J. Ekström
Pages: 977-983
Published online on: 05 September 2011

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Article

Trastuzumab enhances the anti-tumor effects of the histone deacetylase inhibitor sodium butyrate on a HER2-overexpressing breast cancer cell line

Weiwei Chen, Feng Wei, Jing Xu, Yucai Wang, Longbang Chen, Jinghua Wang, Xiaoxiang Guan
Pages: 985-991
Published online on: 01 September 2011

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Article

Expression of interleukin-24 and its receptor in human pancreatic myofibroblasts

Hirotsugu Imaeda, Atsushi Nishida, Osamu Inatomi, Yoshihide Fujiyama, Akira Andoh
Pages: 993-999
Published online on: 12 September 2011

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Article

The potential of mouse skin-derived precursors to differentiate into mesenchymal and neural lineages and their application to osteogenic induction in vivo

Hyun Ki Kang, Seung-Ki Min, Sung Youn Jung, Kyoungsuk Jung, Da Hyun Jang, O Bok Kim, Gae-Sig Chun, Zang Hee Lee, Byung-Moo Min
Pages: 1001-1011
Published online on: 29 August 2011

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Article

Mitigation of 2,4-dinitrofluorobenzene-induced atopic dermatitis-related symptoms by Terminalia chebula Retzius

Dong-Yoon Nam, Jin-Man Lee, Jin-Chul Heo, Sang-Han Lee
Pages: 1013-1018
Published online on: 07 September 2011

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Article

Differentiation of PDX1 gene-modified human umbilical cord mesenchymal stem cells into insulin-producing cells in vitro

Dongmei He, Juan Wang, Yangjun Gao, Yuan Zhang
Pages: 1019-1024
Published online on: 11 August 2011

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Article

Novel GATA4 mutations in lone atrial fibrillation

Jin-Qi Jiang, Fang-Fang Shen, Wei-Yi Fang, Xu Liu, Yi-Qing Yang
Pages: 1025-1032
Published online on: 26 August 2011

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Article

Thermosensitization and induction of apoptosis or cell-cycle arrest via the MAPK cascade by parthenolide, an NF-κB inhibitor, in human prostate cancer androgen-independent cell lines

Sachiko Hayashi, Ken Koshiba, Masanori Hatashita, Takefumi Sato, Yutaka Jujo, Ryuta Suzuki, Yukie Tanaka, Hiroki Shioura
Pages: 1033-1042
Published online on: 29 July 2011

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Article

Benzyl isothiocyanate sensitizes human pancreatic cancer cells to radiation by inducing apoptosis

Maki Ohara, Shinichi Kimura, Aya Tanaka, Ken Ohnishi, Ryuichi Okayasu, Nobuo Kubota
Pages: 1043-1047
Published online on: 10 August 2011

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Article

Honokiol stimulates osteoblastogenesis by suppressing NF-κB activation

Masayoshi Yamaguchi, Jack L. Arbiser, M. Neale Weitzmann
Pages: 1049-1053
Published online on: 31 August 2011

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Article

The potential role of human osteoblasts for periprosthetic osteolysis following exposure to wear particles

Katrin Lochner, Andreas Fritsche, Anika Jonitz, Doris Hansmann, Petra Mueller, Brigitte Mueller-Hilke, Rainer Bader
Pages: 1055-1063
Published online on: 17 August 2011

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Article

Suppression of proliferation and oxidative stress by extracts of Ganoderma lucidum in the ovarian cancer cell line OVCAR-3

Tze-Chen Hsieh, Joseph M. Wu
Pages: 1065-1069
Published online on: 01 September 2011

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Article

Expression and characterization of recombinant human milk fat globule-EGF factor VIII

Xiaoling Qiang, Jianhua Li, Rongqian Wu, Youxin Ji, Wayne Chaung, Weifeng Dong, Ping Wang
Pages: 1071-1076
Published online on: 26 August 2011

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Article

Activation of the δ-opioid receptor inhibits serum deprivation-induced apoptosis of human liver cells via the activation of PKC and the mitochondrial pathway Retraction in /10.3892/ijmm.2023.5254

Bo Tang, Yi Zhang, Rui Liang, Peng Yuan, Jian Du, Hongxin Wang, Liming Wang
Pages: 1077-1085
Published online on: 26 August 2011

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Article

The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. I. Intraperitoneal glucose tolerance test

Zoheir Mellouk, Tarek Hachimi Idrissi, Karim Louchami, Emeline Hupkens, Willy J. Malaisse, Dalila Ait Yahia, Abdullah Sener
Pages: 1087-1092
Published online on: 24 August 2011

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Article

Influence of CYP3A5 and ABCB1 gene polymorphisms and other factors on tacrolimus dosing in Caucasian liver and kidney transplant patients

Alessio Provenzani, Monica Notarbartolo, Manuela Labbozzetta, Paola Poma, Giovanni Vizzini, Paola Salis, Chiara Caccamo, Tullio Bertani, Ugo Palazzo, Piera Polidori, Bruno Gridelli, Natale D'Alessandro
Pages: 1093-1102
Published online on: 12 September 2011

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Review Open Access

Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Review Open Access

Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

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